23 results on '"Bianchi ET"'
Search Results
2. Apollinaire soldat, ou l’Aventure. Variations génériques et discursives
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WAHL, Philippe, Passages XX-XXI (XXI), Université Lumière - Lyon 2 (UL2), and Nicolas Bianchi et Toby Garfitt (eds).
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épistolaire ,interdiscours ,[SHS.LITT]Humanities and Social Sciences/Literature ,stylisation ,ethos ,Apollinaire ,Breton ,prose poétique ,syntaxe mimétique ,stylistique ,vers libre ,énonciation ,lyrisme ,[SHS.LANGUE]Humanities and Social Sciences/Linguistics - Abstract
International audience; Comment écrire la Grande Guerre ? Pour Apollinaire, la guerre a d’abord été une expérience nouvelle, offrant des ressorts « fantastiques » à la création poétique. L’accent est ici déplacé vers sa prose épistolaire et journalistique, dont la diversité énonciative et formelle met en jeu un ethos à facettes multiples (soldat, poète, amant). Les variations textuelles sur des scènes topiques (baptême du feu, égarement dans le no man’s land), montrent comment la poéticité de la prose fait lien entre témoignage et formes poétiques. Un travail sensible de stylisation conduit à éviter les registres épique ou pathétique, au profit d’une phénoménologie singulière placée sous le signe de la simplicité. Cette prose parfois réflexive, tissée d’interdiscours (militaire, populaire, littéraire), contribue aussi à situer Apollinaire dans un champ littéraire en mutation. Son imaginaire de « l’Aventure » compose avec « l’Ordre », dans une posture qui portera bientôt la marque d’une époque révolue.
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- 2017
3. Introduction. Deux champs littéraires dans la tourmente de 14-18
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Nicolas Bianchi, des publications scientifiques, Base, Nicolas Bianchi et Toby Garfitt, Représenter, Inventer la Réalité, du Romantisme au XXIe siècle (RIRRA 21), and Université Paul-Valéry - Montpellier 3 (UPVM)
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[SHS.LITT] Humanities and Social Sciences/Literature ,[SHS.LITT]Humanities and Social Sciences/Literature ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2017
4. Des histoires à l’Histoire. L’héritage paradoxal de Montesquieu dans l’œuvre de William Robertson
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Spector, Céline, Sciences, Normes, Décision (SND), Université Paris-Sorbonne (UP4)-Centre National de la Recherche Scientifique (CNRS), and L. Bianchi et R. Minuti
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[SHS.PHIL]Humanities and Social Sciences/Philosophy ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2014
5. 'Le mote ne fait rien à la chose' : des gardes bourgeoises aux gardes nationales à Bruxelles et Namur, 1706-1814
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Denys, Catherine, Institut de Recherches Historiques du Septentrion (IRHiS) - UMR 8529 (IRHiS), Université de Lille-Centre National de la Recherche Scientifique (CNRS), and Serge BIANCHI et Roger DUPUY
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Belgique ,police ,Bruxelles ,Namur ,[SHS.HIST]Humanities and Social Sciences/History ,gardes bourgeoises ,gardes nationales - Published
- 2006
6. Loustics, balourds et picaros. Regards sur le personnage comique romanesque de 14-18
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Nicolas Bianchi, Représenter, Inventer la Réalité, du Romantisme au XXIe siècle (RIRRA 21), Université Paul-Valéry - Montpellier 3 (UPVM), Nicolas Bianchi et Toby Garfitt, and des publications scientifiques, Base
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[SHS.LITT] Humanities and Social Sciences/Literature ,[SHS.LITT]Humanities and Social Sciences/Literature ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
7. MANAGEMENT OF SYMPTOMS RECURRENCE AFTER MYOTOMY FOR ACHALASIA. A PRACTICAL APPROACH.
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Tustumi F, Szachnowicz S, Andreollo NA, Seguro FCBDC, Bianchi ET, Duarte AF, Nasi A, and Sallum RAA
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- Humans, Deglutition Disorders etiology, Endoscopy, Esophageal Sphincter, Lower surgery, Esophagectomy, Natural Orifice Endoscopic Surgery, Treatment Outcome, Esophageal Achalasia diagnosis, Esophageal Achalasia surgery, Myotomy adverse effects, Myotomy methods
- Abstract
Background: Achalasia is an esophageal motility disorder, and myotomy is one of the most used treatment techniques. However, symptom persistence or recurrence occurs in 9 to 20% of cases., Aims: This study aims to provide a practical approach for managing the recurrence or persistence of achalasia symptoms after myotomy., Methods: A critical review was performed to gather evidence for a rational approach for managing the recurrence or persistence of achalasia symptoms after myotomy., Results: To properly manage an achalasia patient with significant symptoms after myotomy, such as dysphagia, regurgitation, thoracic pain, and weight loss, it is necessary to classify symptoms, stratify severity, perform appropriate tests, and define a treatment strategy. A systematic differential diagnosis workup is essential to cover the main etiologies of symptoms recurrence or persistence after myotomy. Upper digestive endoscopy and dynamic digital radiography are the main tests that can be applied for investigation. The treatment options include endoscopic dilation, peroral endoscopic myotomy, redo surgery, and esophagectomy, and the decision should be based on the patient's individual characteristics., Conclusions: A good clinical evaluation and the use of proper tests jointly with a rational assessment, are essential for the management of symptoms recurrence or persistence after achalasia myotomy.
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- 2023
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8. Managing Esophageal-gastric Junction Outflow Obstruction with Hiatal Hernia.
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Arienzo VP, Bianchi ET, Szor DJ, and Tustumi F
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- Humans, Esophagogastric Junction, Hernia, Hiatal complications, Hernia, Hiatal surgery, Gastroesophageal Reflux
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- 2023
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9. Measuring the burden of gastroesophageal reflux after per-oral endoscopic myotomy.
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Tustumi F, Bianchi ET, and Szor DJ
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- Humans, Fundoplication, Treatment Outcome, Esophageal Sphincter, Lower surgery, Gastroesophageal Reflux etiology, Gastroesophageal Reflux surgery, Digestive System Surgical Procedures, Myotomy, Esophageal Achalasia surgery
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- 2023
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10. Laparoscopic total fundoplication is superior to medical treatment for reducing the cancer risk in Barrett's esophagus: a long-term analysis.
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Szachnowicz S, Duarte AF, Nasi A, da Rocha JRM, Seguro FB, Bianchi ET, Tustumi F, de Moura EGH, Sallum RAA, and Cecconello I
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- Humans, Fundoplication, Prospective Studies, Omeprazole, Barrett Esophagus complications, Barrett Esophagus drug therapy, Barrett Esophagus surgery, Esophageal Neoplasms etiology, Esophageal Neoplasms prevention & control, Esophageal Neoplasms diagnosis, Adenocarcinoma etiology, Adenocarcinoma prevention & control, Adenocarcinoma surgery, Laparoscopy
- Abstract
The present study aims to compare the effectiveness of surgical and medical therapy in reducing the risk of cancer in Barrett's esophagus in a long-term evaluation. A prospective cohort was designed that compared Barrett's esophagus patients submitted to medical treatment with omeprazole or laparoscopic Nissen fundoplication. The groups were compared using propensity score matching paired by Barrett's esophagus length. A total of 398 patients met inclusion criteria. There were 207 patients in the omeprazole group (Group A) and 191 in the total fundoplication group (Group B). After applying the propensity score matching paired by Barrett's esophagus length, the groups were 180 (Group A) and 190 (Group B). Median follow-up was 80 months. Group B was significantly superior for controlling GERD symptoms. Group B was more efficient than Group A in promoting Barrett's esophagus regression or blocking its progression. Group B was more efficient than Group A in preventing the development of dysplasia and cancer. Logistic regression was performed for the outcomes of adenocarcinoma and dysplasia. Age and body mass index were used as covariates in the logistic regression models. Even after regression analysis, Group B was still superior to Group A to prevent esophageal adenocarcinoma or dysplasia transformation (odds ratio [OR]: 0.51; 95% confidence interval [CI]: 0.27-0.97, for adenocarcinoma or any dysplasia; and OR: 0.26; 95% CI: 0.08-0.81, for adenocarcinoma or high-grade dysplasia). Surgical treatment is superior to medical management, allowing for better symptom control, less need for reflux medication use, higher regression rate of the columnar epithelium and intestinal metaplasia, and lower risk for progression to dysplasia and cancer., (© The Author(s) 2022. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2022
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11. Abdominal Viscera Migration Performing Hemodynamic Instability after Esophagectomy: A Case Report.
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Torres de Lima I, Bianchi ET, Lunardi Aranha G, Camargo Azevedo B, Naccache Namur G, and Pirola Kruger JA
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Hiatal hernia is a rare postoperative complication of esophagectomy in the treatment of esophageal cancer. Although rare, its incidence increased after the establishment of minimally invasive surgical techniques. The patient is usually oligosymptomatic, and the diagnosis is made in the late postoperative period, during outpatient follow-up. The initial presentation of hiatus hernia with hemodynamic instability is a rare condition that has never been described in the literature before. In the following report, we address the clinical picture, diagnosis, and treatment for this condition, discussing the main nuances of the literature., Competing Interests: The authors have no conflicts of interest to declare., (Copyright © 2021 by S. Karger AG, Basel.)
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- 2021
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12. Surgical management of esophageal stenosis due to ingestion of corrosive substances.
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Tustumi F, Seguro FCBDC, Szachnowicz S, Bianchi ET, Morrell ALG, da Silva MO, Duarte AF, de Sousa JHB, Laureano GG, da Rocha JRM, Sallum RAA, and Cecconello I
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- Behavior Therapy, Burns, Chemical etiology, Burns, Chemical mortality, Burns, Chemical psychology, Depression complications, Depression epidemiology, Depression psychology, Depression therapy, Esophageal Stenosis chemically induced, Esophageal Stenosis mortality, Esophageal Stenosis psychology, Esophagus pathology, Esophagus surgery, Humans, Nutritional Support, Patient Care Team, Risk Factors, Self-Injurious Behavior etiology, Self-Injurious Behavior mortality, Self-Injurious Behavior psychology, Substance-Related Disorders complications, Substance-Related Disorders etiology, Substance-Related Disorders psychology, Substance-Related Disorders therapy, Treatment Outcome, Burns, Chemical therapy, Caustics poisoning, Esophageal Stenosis therapy, Esophagectomy statistics & numerical data, Self-Injurious Behavior therapy
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Background: Corrosive ingestion is a significant challenge for healthcare systems. Limited data are available regarding the best treatments, and there remains a lack of consensus about the optimal surgical approach and its outcomes. This study aims to review the current literature and show a single institution's experience regarding the surgical treatment of esophageal stenosis due to corrosive substance ingestion., Methods: A retrospective review that accounted for demographics, psychiatric profiles, surgical procedures, and outcomes was performed. A systematic review of the literature was performed using PubMed., Results: In total, 27 surgical procedures for esophageal stenosis due to corrosive substance ingestion were performed from 2010 to 2019. Depression and drug abuse were diagnosed in 30% and 22% of the included patients, respectively. Esophagectomies and esophageal bypasses were performed in 13 and 14 patients, respectively. No 30-day mortality was recorded., Conclusion: Surgical intervention either by esophagectomy or esophageal bypass results in durable relief from dysphagia. However, successful clinical outcomes depend on a high-quality multidisciplinary network of esophageal and thoracic surgeons, intensivists, psychologists, psychiatrists, and nutritional teams., (Copyright © 2021. Published by Elsevier Inc.)
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- 2021
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13. The Mechanisms for the Association of Cancer and Esophageal Dysmotility Disorders.
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Tustumi F, de Sousa JHB, Dornelas NM, Rosa GM, Steinman M, and Bianchi ET
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- Humans, Adenocarcinoma complications, Carcinoma, Squamous Cell, Esophageal Achalasia diagnosis, Esophageal Motility Disorders complications, Esophageal Neoplasms diagnosis
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Background: Achalasia and other esophageal dysmotility disorders mimicking achalasia can be associated with cancer. This study aimed to review the main mechanisms for which cancer may develop in esophageal dysmotility disorder patients., Methods: A narrative review was performed., Results: The mechanism for developing squamous cell carcinoma and adenocarcinoma are discussed. Besides, achalasia-like syndromes related to familial KIT-gene mutation and pseudoachalasia are discussed., Conclusions: Knowing the main mechanism for which achalasia can be related to cancer is essential for clinicians to conduct the proper investigation, surveillance, and treatment.
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- 2021
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14. Anti-reflux surgery for controlling respiratory symptoms of gastro-esophageal reflux disease: A systematic review and meta-analysis.
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Tustumi F, Bernardo WM, Mariano da Rocha JR, Szachnowicz S, Bernal da Costa Seguro FC, Bianchi ET, Takeda FR, Afonso de Miranda Neto A, Aissar Sallum RA, and Cecconello I
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- Female, Fundoplication methods, Humans, Male, Treatment Outcome, Cough etiology, Cough therapy, Digestive System Surgical Procedures methods, Gastroesophageal Reflux complications, Gastroesophageal Reflux surgery, Hoarseness etiology, Hoarseness therapy, Pulmonary Disease, Chronic Obstructive etiology, Pulmonary Disease, Chronic Obstructive therapy, Respiratory Sounds etiology
- Abstract
Gastro-esophageal reflux disease (GERD) patients have a higher prevalence of airway symptoms, such as chronic cough, wheezing, and hoarseness. The therapeutic management of patients with these symptoms is controversial. Therefore, this study aims to perform a systematic review and meta-analysis evaluating the efficacy of anti-reflux surgery for controlling respiratory symptoms related to GERD. A systematic review and meta-analysis was performed. Extraction of the data concerning proportions of participants who were not free of respiratory symptoms related to GERD (cough, wheezing, hoarseness) or not substantially improved at follow-ups (failure to cure) was performed. Of the 3,424 initially screened articles, 68 studies were included for systematic review and 61 were included for meta-analysis, with a cumulative sample size of 3,869 patients. Of all the included patients, after anti-reflux surgery, the general symptoms improvement was 80% (95% CI 75.2-84%). The numbers needed to harm (NNH) and the numbers needed to treat (NNT) were 15.21 and 1.23, respectively. Of the included patients, 83.4% (95% CI 78.3-87.5%) patients reported improvement in cough symptoms after surgery. For the wheezing symptom, 71.5% (95% CI 62.9-78.8%) reported improvement after surgery. Moreover, surgery presented better results in improving respiratory symptoms than medical therapy (risk difference: -0.46; 95% CI -0.77, -0.16). Physicians should strongly consider surgical anti-reflux procedures for controlling respiratory symptoms in GERD patients after proper patient selection. Anti-reflux surgery has shown high efficacy in improving respiratory symptoms related to GERD, even when compared to medical therapy., Competing Interests: Declaration of competing interest The authors declare that they have no competing interests., (Copyright © 2020. Published by Elsevier Taiwan LLC.)
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- 2021
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15. Preoperative botulinum toxin type A: A case report of a proposed new strategy for giant hiatal hernia management.
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Tustumi F, Bianchi ET, Szachnowicz S, Cedro RM, de Miranda Neto AA, Morrell ALG, Abdalla RZ, Sallum RAA, and Cecconello I
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The use of preoperative ventral botulinum toxin for giant hiatal hernia management., Competing Interests: Authors have no conflict of interest., (© 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
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- 2020
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16. Impact of fundoplication for gastroesophageal reflux in the outcome of benign tracheal stenosis.
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Bianchi ET, Guerreiro Cardoso PF, Minamoto H, Bibas BJ, Salati M, and Pego-Fernandes PM
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- Adolescent, Adult, Aged, Aged, 80 and over, Female, Fundoplication adverse effects, Gastroesophageal Reflux complications, Gastroesophageal Reflux diagnosis, Humans, Male, Middle Aged, Omeprazole adverse effects, Proton Pump Inhibitors adverse effects, Retrospective Studies, Time Factors, Tracheal Stenosis diagnosis, Tracheal Stenosis etiology, Treatment Outcome, Young Adult, Fundoplication methods, Gastroesophageal Reflux surgery, Laparoscopy adverse effects, Omeprazole therapeutic use, Proton Pump Inhibitors therapeutic use, Tracheal Stenosis surgery, Watchful Waiting
- Abstract
Objective: This study focuses on the impact of antireflux surgery in the outcome of tracheal stenosis., Methods: We performed a retrospective study including patients with benign tracheal stenosis who underwent esophageal manometry and dual-probe 24-hour ambulatory esophageal pH study. Patients with an abnormal pH study were managed with laparoscopic modified Nissen fundoplication or medically (omeprazole 80 mg/d, orally). Patients with normal pH study results were observed. After a 24-month follow-up, the outcome was considered satisfactory if tracheal stenosis could be managed by resection and there was no need for further dilatation or definitive decannulation. The management groups were compared using propensity score matching., Results: A total of 175 patients were included. Abnormal pH study results were found in 74 patients (42.3%), and 12.6% of patients had typical gastroesophageal reflux symptoms. Follow-up was completed in 124 patients (20 had fundoplication, 32 received omeprazole, and 72 were observed). After propensity score matching, the outcome of tracheal stenosis in the fundoplication group was similar to that of the observation group (odds ratio, 1; P = .99) and better than that of the omeprazole group (odds ratio, 5.31; P = .03). The observation (no gastroesophageal reflux) group had a better outcome of stenosis than those treated with omeprazole (odds ratio, 3.54; P = .02)., Conclusions: The outcome of the airway stenosis was superior after laparoscopic fundoplication compared with medical treatment with omeprazole and was similar to the outcome of patients without gastroesophageal reflux. A prospective randomized trial is warranted., (Copyright © 2019 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.)
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- 2019
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17. Surgical treatment of Killian-Jamieson diverticulum: A case report and literature review.
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Jeismann VB, Bianchi ET, Szachnowicz S, Seguro FCBDC, Tustumi F, Duarte AF, Sallum RAA, and Cecconello I
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This study describes a patient with symptomatic Killian-Jamieson, a rare entity, successfully treated by cervical approach with diverticulum resection and esophagomyotomy., Competing Interests: None declared.
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- 2019
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18. Surgical Management of Malignant Intestinal Obstruction: Outcome and Prognostic Factors.
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Bento JH, Bianchi ET, Tustumi F, Leonardi PC, Junior UR, and Ceconello I
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- Colorectal Neoplasms complications, Female, Genital Neoplasms, Female complications, Humans, Intestinal Obstruction etiology, Intestinal Obstruction mortality, Neoplasms complications, Prognosis, Retrospective Studies, Colorectal Neoplasms surgery, Genital Neoplasms, Female surgery, Intestinal Obstruction surgery
- Abstract
Background: Malignant intestinal obstruction is a frequent complication in advanced stages cancer patients. The prognosis is poor, with mean survival rate beneath 3 months. Clinical treatment, endoscopic or surgical procedures are options for malignant intestinal obstruction management. There is no generally accepted management strategy. Objectives: To evaluate prognostic factors of patients with malignant intestinal obstruction who underwent surgical treatment. Methods: A retrospective analysis was performed including patients of a single institution with diagnosis of malignant intestinal obstruction. Demographic data, in-hospital stay, postoperative complications, and overall survival were assessed. Logistic regression was used to evaluate associated prognostic factors. Results: Two hundred thirty-three surgeries were performed due to suspicion for malignant intestinal obstruction over a seven-year period. This diagnosis was confirmed in 210 operations (90.1%). The main causes of malignant obstruction were colorectal (49.5%) and gynecological cancer (21.9%). The rate of severe complications was 11.42%. In-hospital mortality rate was 40.95% (CI 95%: 34.16-47.74%). Functional status impairment,high serum urea, and low albumin levels were associated to higher mortality rate. Conclusion: Malignant intestinal obstruction implies poor prognosis, with high in-hospital mortality rate and severe postoperative complications. The decision regarding management of malignant intestinal obstruction must be multimodal and individualized, according to individual prognostic factors., (Celsius.)
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- 2019
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19. A case report of esophageal heterotopic pancreas presenting as recurrent mediastinal abscess, treated by minimally invasive esophagectomy.
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Bianchi ET, Tustumi F, Fonseca Duarte A, Ortiz ES, Szachnowicz S, da Costa Seguro FCB, Aissar Sallum RA, and Cecconello I
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Introduction: Heterotopic pancreas is a rare congenital anomaly. We report a case of esophageal heterotopic pancreas complicated by recurrent mediastinal abscess and treated by minimally invasive resection., Presentation of Case: A 31-year-old woman was admitted with a history of recurrent chest pain, dysphagia, and heartburn. CT scan revealed focal confined collection in the lower mediastinum surrounding esophagus. Endoscopic ultrasound revealed a subepithelial lesion. The patient was treated by minimally invasive esophagectomy and made an uneventful postoperative recovery., Discussion: The management of subepithelial lesions would depend on their size, ability to exclude other etiologies and their associated symptoms. The patient, in this case, was obviously symptomatic and accurate differentiation from malignant etiologies could not be accurately made., Conclusion: Although pancreatic heterotopia is rare, it should be remembered in the differential diagnosis of various gastrointestinal lesions., (Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
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- 2019
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20. Esophageal achalasia: a risk factor for carcinoma. A systematic review and meta-analysis.
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Tustumi F, Bernardo WM, da Rocha JRM, Szachnowicz S, Seguro FC, Bianchi ET, Sallum RAA, and Cecconello I
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- Humans, Incidence, Prevalence, Risk Assessment, Risk Factors, Survival Rate, Adenocarcinoma epidemiology, Carcinoma, Squamous Cell epidemiology, Esophageal Achalasia epidemiology, Esophageal Neoplasms epidemiology
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Achalasia of the cardia is associated with an increased risk of esophageal carcinoma. The real burden of achalasia at the malignancy genesis is still a controversial issue. Therefore, there are no generally accepted recommendations on follow-up evaluation for achalasia patients. This study aims to estimate the risk of esophageal adenocarcinoma and squamous cell carcinoma in achalasia patients. We searched for association between carcinoma and esophageal achalasia in databases up to January 2017 to perform a systematic review and meta-analysis. A total of 1,046 studies were identified from search strategy, of which 40 were selected for meta-analysis. A cumulative number of 11,978 esophageal achalasia patients were evaluated. The incidence of squamous cell carcinoma was 312.4 (StDev 429.16) cases per 100,000 patient-years at risk. The incidence of adenocarcinoma was 21.23 (StDev 31.6) cases per 100,000 patient-years at risk. The prevalence for esophageal carcinoma was 28 carcinoma cases in 1,000 esophageal achalasia patients (CI 95% 2, 39). The prevalence for squamous cell carcinoma was 26 cases in 1,000 achalasia patients (CI 95% 18, 39) and for adenocarcinoma was 4 cases in 1,000 achalasia patients (CI 95% 3, 6).The absolute risk increase for squamous cell carcinoma was 308.1 and for adenocarcinoma was 18.03 cases per 100,000 patients per year. To the best of our knowledge, this is the first meta-analysis estimating the burden of achalasia as an esophageal cancer risk factor. The high increased risk rate for cancer in achalasia patients points to a strict endoscopic surveillance for these patients. Also, the increased risk for developing adenocarcinoma in achalasia patients suggests fundoplication after myotomy, to avoid esophageal reflux and Barret esophagus, a known risk factor for adenocarcinoma., (© The Authors 2017. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2017
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21. Prevalence of gallstones in 1,229 patients submitted to surgical laparoscopic treatment of GERD and esophageal achalasia: associated cholecystectomy was a safe procedure.
- Author
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Sallum RA, Padrão EM, Szachnowicz S, Seguro FC, Bianchi ET, and Cecconello I
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- Esophageal Achalasia complications, Female, Gallstones complications, Gastroesophageal Reflux complications, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Cholecystectomy, Esophageal Achalasia surgery, Gallstones epidemiology, Gallstones surgery, Gastroesophageal Reflux surgery, Laparoscopy
- Abstract
Background: Association between esophageal achalasia/ gastroesophageal reflux disease (GERD) and cholelithiasis is not clear. Epidemiological data are controversial due to different methodologies applied, the regional differences and the number of patients involved. Results of concomitant cholecistectomy associated to surgical treatment of both diseases regarding safety is poorly understood., Aim: To analyze the prevalence of cholelithiasis in patients with esophageal achalasia and gastroesophageal reflux submitted to cardiomyotomy or fundoplication. Also, to evaluate the safety of concomitant cholecistectomy., Methods: Retrospective analysis of 1410 patients operated from 2000 to 2013. They were divided into two groups: patients with GERD submitted to laparocopic hiatoplasty plus Nissen fundoplication and patients with esophageal achalasia to laparoscopic cardiomyotomy plus partial fundoplication. It was collected epidemiological data, specific diagnosis and subgroups, the presence or absence of gallstones, surgical procedure, operative and clinical complications and mortality. All groups/subgroups were compared., Results: From 1,229 patients with GERD or esophageal achalasia, submitted to laparoscopic cardiomyotomy or fundoplication, 138 (11.43%) had cholelitiasis, occurring more in females (2.38:1) with mean age of 50,27 years old. In 604 patients with GERD, 79 (13,08%) had cholelitiasis. Lower prevalence occurred in Barrett's esophagus patients 7/105 (6.67%) (p=0.037). In 625 with esophageal achalasia, 59 (9.44%) had cholelitiasis, with no difference between chagasic and idiopathic forms (p=0.677). Complications of patients with or without cholecystectomy were similar in fundoplication and cardiomyotomy (p=0.78 and p=1.00).There was no mortality or complications related to cholecystectomy in this series., Conclusions: Prevalence of cholelithiasis was higher in patients submitted to fundoplication (GERD). Patients with chagasic or idiopatic forms of achalasia had the same prevalence of cholelithiasis. Gallstones occurred more in GERD patients without Barrett's esophagus. Simultaneous laparoscopic cholecystectomy was proved safe.
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- 2015
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22. Abnormal visual activation in Parkinson's disease patients.
- Author
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Cardoso EF, Fregni F, Maia FM, Melo LM, Sato JR, Cruz AC Jr, Bianchi ET, Fernandes DB, Monteiro ML, Barbosa ER, and Amaro E Jr
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- Aged, Analysis of Variance, Face, Female, Humans, Image Processing, Computer-Assisted methods, Magnetic Resonance Imaging methods, Male, Middle Aged, Neurologic Examination methods, Neuropsychological Tests, Oxygen blood, Photic Stimulation methods, Statistics as Topic, Visual Cortex blood supply, Visual Pathways blood supply, Visual Pathways physiopathology, Parkinson Disease complications, Parkinson Disease pathology, Pattern Recognition, Visual physiology, Perceptual Disorders etiology, Visual Cortex physiopathology
- Abstract
Among nonmotor symptoms observed in Parkinson's disease (PD) dysfunction in the visual system, including hallucinations, has a significant impact in their quality of life. To further explore the visual system in PD patients we designed two fMRI experiments comparing 18 healthy volunteers with 16 PD patients without visual complaints in two visual fMRI paradigms: the flickering checkerboard task and a facial perception paradigm. PD patients displayed a decreased activity in the primary visual cortex (Broadmann area 17) bilaterally as compared to healthy volunteers during flickering checkerboard task and increased activity in fusiform gyrus (Broadmann area 37) during facial perception paradigm. Our findings confirm the notion that PD patients show significant changes in the visual cortex system even before the visual symptoms are clinically evident. Further studies are necessary to evaluate the contribution of these abnormalities to the development visual symptoms in PD.
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- 2010
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23. Neurohumoral response to volume depletion and central hypovolemia in dialysis patients.
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Mallamaci F, Tripepi G, Panuccio V, Pennisi F, Benedetto F, and Zoccali C
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- Blood Volume physiology, Endothelin-1 physiology, Hemodynamics physiology, Humans, Hypotension physiopathology, Nitric Oxide physiology, Syncope, Vasovagal physiopathology, Uremia physiopathology, Autonomic Nervous System physiology, Hypotension etiology, Renal Dialysis adverse effects
- Published
- 1996
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