372 results on '"Bignell, Elaine"'
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2. Author Correction: Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging
3. Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging
4. Conserved and Divergent Features of pH Sensing in Major Fungal Pathogens
5. Dynamics of interaction and internalisation of the antifungal protein PeAfpA into Penicillium digitatum morphotypes
6. Epithelial uptake leads to fungal killing in vivo and is aberrant in COPD-derived epithelial cells
7. Tackling the emerging threat of antifungal resistance to human health
8. Bayesian detection of piecewise linear trends in replicated time-series with application to growth data modelling
9. The sulfur-related metabolic status ofAspergillus fumigatusduring infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target
10. Inferring fungal growth rates from optical density data
11. Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis.
12. The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis.
13. Inferring fungal growth rates from optical density data.
14. Heightened Efficacy of Anidulafungin When Used in Combination with Manogepix or 5-Flucytosine against Candida auris In Vitro
15. Secondary metabolite arsenal of an opportunistic pathogenic fungus
16. The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
17. Functional analysis of the Aspergillus fumigatus kinome reveals a DYRK kinase involved in septal plugging is a novel antifungal drug target
18. Developing novel antifungals: lessons from G protein-coupled receptors
19. 2 Aspergillus fumigatus: Saprotroph to Pathogen
20. Subtelomeres of Aspergillus Species
21. Aspergillus fumigatus Drives Tissue Damage via Iterative Assaults upon Mucosal Integrity and Immune Homeostasis
22. Heightened efficacy of anidulafungin when used in combination with manogepix or 5-flucytosine againstCandida auris in vitro
23. Mutual independence of alkaline‐ and calcium‐mediated signalling in Aspergillus fumigatus refutes the existence of a conserved druggable signalling nexus
24. Distinct Cohorts of Aspergillus fumigatus Transcription Factors Are Required for Epithelial Damage Occurring via Contact- or Soluble Effector-Mediated Mechanisms
25. Tackling the emerging threat of antifungal resistance to human health
26. Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus
27. Exploring a novel genomic safe-haven site in the human pathogenic mould Aspergillus fumigatus
28. Impaired Interferon-γ Responses, Increased Interleukin-17 Expression, and a Tumor Necrosis Factor–α Transcriptional Program in Invasive Aspergillosis
29. Pathogenesis of Respiratory Viral and Fungal Coinfections
30. Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein
31. Complete nucleotide sequences of four dsRNAs associated with a new chrysovirus infecting Aspergillus fumigatus
32. Aspergillus fumigatus drives tissue damage via iterative assaults upon mucosal integrity and immune homeostasis
33. Reactive Oxygen Intermediates, pH, and Calcium
34. Live-cell imaging of rapid calcium dynamics using fluorescent, genetically-encoded GCaMP probes with Aspergillus fumigatus
35. Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response
36. Subtelomeres of Aspergillus Species
37. Incidence of dsRNA Mycoviruses in a Collection of Aspergillus fumigatus Isolates
38. Complete nucleotide sequences of two dsRNAs associated with a new partitivirus infecting Aspergillus fumigatus
39. Ambient pH gene regulation in fungi: making connections
40. 2 Aspergillus fumigatus: Saprotroph to Pathogen
41. Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence
42. Development of a marker-free mutagenesis system using CRISPR-Cas9 in the pathogenic mould Aspergillus fumigatus
43. The Molecular Basis of pH Sensing, Signaling, and Homeostasis in Fungi
44. Conservation in Aspergillus fumigatus of pH-signaling seven transmembrane domain and arrestin proteins, and implications for drug discovery
45. On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction
46. Host–fungal interactions: key players of antifungal immunity
47. Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence
48. Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence
49. On the lineage of Aspergillus fumigatus isolates in common laboratory use
50. Therapeutic jackpots lie within the reach of multiscale and integrated mycological research
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