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326 results on '"Billeter, Adrian T."'

2. Defining and Predicting Early Recurrence for Optimal Treatment Strategies for Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: An International Multicenter Study

Author

Habib, Joseph R., Javed, Ammar A., Rompen, Ingmar F., Hidalgo Salinas, Camila, Sorrentino, Anthony, Campbell, Brady A., Andel, Paul C. M., Groot, Vincent P., Lafaro, Kelly J., Sacks, Greg D., Billeter, Adrian T., Molenaar, I. Quintus, Müller-Stich, Beat P., Besselink, Marc G., He, Jin, Wolfgang, Christopher L., and Daamen, Lois A.

Published
2025
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8. ASO Visual Abstract: Defining and Predicting Early Recurrence for Optimal Treatment Strategies in Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer––An International Multicenter Study: Early Recurrence in IPMN-Derived Pancreatic Cancer

Author

Habib, Joseph R., Javed, Ammar A., Rompen, Ingmar F., Salinas, Camila Hidalgo, Sorrentino, Anthony, Campbell, Brady A., Andel, Paul C. M., Groot, Vincent P., Lafaro, Kelly J., Sacks, Greg D., Billeter, Adrian T., Molenaar, I. Quintus, Müller-Stich, Beat P., Besselink, Marc G., He, Jin, Wolfgang, Christopher L., and Daamen, Lois A.

Published
2025
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15. Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia

Author

Taylor, Jacqueline, Uhl, Leonie, Moll, Iris, Hasan, Sana Safatul, Wiedmann, Lena, Morgenstern, Jakob, Giaimo, Benedetto Daniele, Friedrich, Tobias, Alsina-Sanchis, Elisenda, De Angelis Rigotti, Francesca, Mülfarth, Ronja, Kaltenbach, Sarah, Schenk, Darius, Nickel, Felix, Fleming, Thomas, Sprinzak, David, Mogler, Carolin, Korff, Thomas, Billeter, Adrian T., Müller-Stich, Beat P., Berriel Diaz, Mauricio, Borggrefe, Tilman, Herzig, Stephan, Rohm, Maria, Rodriguez-Vita, Juan, and Fischer, Andreas

Published
2023
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19. Toward a Standardization of Learning Curve Assessment in Minimally Invasive Liver Surgery.

Author

Kuemmerli, Christoph, Toti, Johannes M.A., Haak, Fabian, Billeter, Adrian T., Nickel, Felix, Guidetti, Cristiano, Santibanes, Martin, Vigano, Luca, Lavanchy, Joël L., Kollmar, Otto, Seehofer, Daniel, Abu Hilal, Mohammed, Di Benedetto, Fabrizio, Clavien, Pierre-Alain, Dutkowski, Philipp, Müller, Beat P., and Müller, Philip C.

Abstract

Objective: The aim was to analyze the learning curves of minimal invasive liver surgery (MILS) and propose standardized reporting. Background: MILS offers benefits compared with open resections. For a safe introduction along the learning curve, formal training is recommended. However, definitions of learning curves and methods to assess it lack standardization. Methods: A systematic review of PubMed, Web of Science, and CENTRAL databases identified studies on learning curves in MILS. The primary outcome was the number needed to overcome the learning curve. Secondary outcomes included endpoints defining learning curves and characterization of different learning phases (competency, proficiency, and mastery). Results: Sixty articles with 12,241 patients and 102 learning curve analyses were included. The laparoscopic and robotic approach was evaluated in 71 and 18 analyses and both approaches combined in 13 analyses. Sixty-one analyses (60%) based the learning curve on statistical calculations. The most often used parameters to define learning curves were operative time (n=64), blood loss (n=54), conversion (n=42), and postoperative complications (n=38). Overall competency, proficiency, and mastery were reached after 34 [interquartile range (IQR) 19–56], 50 (IQR 24–74), and 58 (IQR 24–100) procedures, respectively. Intraoperative parameters improved earlier (operative time: competency to proficiency to mastery: −13%, 2%; blood loss: competency to proficiency to mastery: –33%, 0%; conversion rate (competency to proficiency to mastery; −21%, −29%), whereas postoperative complications improved later (competency to proficiency to mastery: −25%, −41%). Conclusions: This review summarizes the highest evidence on learning curves in MILS taking into account different definitions and confounding factors. A standardized 3-phase reporting of learning phases (competency, proficiency, and mastery) is proposed and should be followed. [ABSTRACT FROM AUTHOR]

Published
2025
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25. Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH

Author

Dudek, Michael, Pfister, Dominik, Donakonda, Sainitin, Filpe, Pamela, Schneider, Annika, Laschinger, Melanie, Hartmann, Daniel, Hüser, Norbert, Meiser, Philippa, Bayerl, Felix, Inverso, Donato, Wigger, Jennifer, Sebode, Marcial, Öllinger, Rupert, Rad, Roland, Hegenbarth, Silke, Anton, Martina, Guillot, Adrien, Bowman, Andrew, Heide, Danijela, Müller, Florian, Ramadori, Pierluigi, Leone, Valentina, Garcia-Caceres, Cristina, Gruber, Tim, Seifert, Gabriel, Kabat, Agnieszka M., Mallm, Jan-Philipp, Reider, Simon, Effenberger, Maria, Roth, Susanne, Billeter, Adrian T., Müller-Stich, Beat, Pearce, Edward J., Koch-Nolte, Friedrich, Käser, Rafael, Tilg, Herbert, Thimme, Robert, Boettler, Tobias, Tacke, Frank, Dufour, Jean-Francois, Haller, Dirk, Murray, Peter J., Heeren, Ron, Zehn, Dietmar, Böttcher, Jan P., Heikenwälder, Mathias, and Knolle, Percy A.

Published
2021
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31. Evidence mapping on how to perform an optimal surgical repair of large hiatal hernias.

Author

Nickel, Felix, Müller, Philip C., Cizmic, Amila, Häberle, Frida, Muller, Markus K., Billeter, Adrian T., Linke, Georg R., Mann, Oliver, Hackert, Thilo, Gutschow, Christian A., and Müller-Stich, Beat P.

Subjects
HIATAL hernia, MINIMALLY invasive procedures, VAGUS nerve, GASTROESOPHAGEAL reflux, EVIDENCE-based medicine, FUNDOPLICATION
Abstract

Background: Symptomatic and large hiatal hernia (HH) is a common disorder requiring surgical management. However, there is a lack of systematic, evidence-based recommendations summarizing recent reviews on surgical treatment of symptomatic HH. Therefore, this systematic review aimed to create evidence mapping on the key technical issues of HH repair based on the highest available evidence. Methods: A systematic review identified studies on eight key issues of large symptomatic HH repair. The literature was screened for the highest level of evidence (LE from level 1 to 5) according to the Oxford Center for evidence-based medicine's scale. For each topic, only studies of the highest available level of evidence were considered. Results: Out of the 28.783 studies matching the keyword algorithm, 47 were considered. The following recommendations could be deduced: minimally invasive surgery is the recommended approach (LE 1a); a complete hernia sac dissection should be considered (LE 3b); extensive division of short gastric vessels cannot be recommended; however, limited dissection of the most upper vessels may be helpful for a floppy fundoplication (LE 1a); vagus nerve should be preserved (LE 3b); a dorso-ventral cruroplasty is recommended (LE 1b); routine fundoplication should be considered to prevent postoperative gastroesophageal reflux (LE 2b); posterior partial fundoplication should be favored over other forms of fundoplication (LE 1a); mesh augmentation is indicated in large HH with paraesophageal involvement (LE 1a). Conclusion: The current evidence mapping is a reasonable instrument based on the best evidence available to guide surgeons in determining optimal symptomatic and large HH repair. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Semaphorin 3C exacerbates liver fibrosis

Author

De Angelis Rigotti, Francesca, primary, Wiedmann, Lena, additional, Hubert, Max Ole, additional, Vacca, Margherita, additional, Hasan, Sana S., additional, Moll, Iris, additional, Carvajal, Silvia, additional, Jiménez, Wladimiro, additional, Starostecka, Maja, additional, Billeter, Adrian T., additional, Müller-Stich, Beat, additional, Wolff, Gretchen, additional, Ekim-Üstünel, Bilgen, additional, Herzig, Stephan, additional, Fandos-Ramo, Cristina, additional, Krätzner, Ralph, additional, Reich, Maria, additional, Keitel-Anselmino, Verena, additional, Heikenwälder, Mathias, additional, Mogler, Carolin, additional, Fischer, Andreas, additional, and Rodriguez-Vita, Juan, additional

Published
2023
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33. Author Correction: Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH

Author

Dudek, Michael, Pfister, Dominik, Donakonda, Sainitin, Filpe, Pamela, Schneider, Annika, Laschinger, Melanie, Hartmann, Daniel, Hüser, Norbert, Meiser, Philippa, Bayerl, Felix, Inverso, Donato, Wigger, Jennifer, Sebode, Marcial, Öllinger, Rupert, Rad, Roland, Hegenbarth, Silke, Anton, Martina, Guillot, Adrien, Bowman, Andrew, Heide, Danijela, Müller, Florian, Ramadori, Pierluigi, Leone, Valentina, Garcia-Caceres, Cristina, Gruber, Tim, Seifert, Gabriel, Kabat, Agnieszka M., Mallm, Jan-Philipp, Reider, Simon, Effenberger, Maria, Roth, Susanne, Billeter, Adrian T., Müller-Stich, Beat, Pearce, Edward J., Koch-Nolte, Friedrich, Käser, Rafael, Tilg, Herbert, Thimme, Robert, Boettler, Tobias, Tacke, Frank, Dufour, Jean-Francois, Haller, Dirk, Murray, Peter J., Heeren, Ron, Zehn, Dietmar, Böttcher, Jan P., Heikenwälder, Mathias, and Knolle, Percy A.

Published
2021
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43. Cited4 is a sex‐biased mediator of the antidiabetic glitazone response in adipocyte progenitors

Author

Bayindir‐Buchhalter, Irem, Wolff, Gretchen, Lerch, Sarah, Sijmonsma, Tjeerd, Schuster, Maximilian, Gronych, Jan, Billeter, Adrian T, Babaei, Rohollah, Krunic, Damir, Ketscher, Lars, Spielmann, Nadine, Hrabe de Angelis, Martin, Ruas, Jorge L, Müller‐Stich, Beat P, Heikenwalder, Mathias, Lichter, Peter, Herzig, Stephan, and Vegiopoulos, Alexandros

Published
2018
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