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12. Development of aeronautical epoxy nanocomposites having an integrated self-healing ability

Author

Guadagno, Liberata, Vertuccio, Luigi, Naddeo, Carlo, Calabrese, Elisa, Barra, Giuseppina, Raimondo, Marialuigia, Sorrentino, Andrea, Binder, W. H., Michael, Philipp, and Rana, Sravendra

Abstract

Functionalized multi-wall carbon nanotubes (MWCNTs) have been embedded in a rubber-toughened epoxy formulation in order to explore the possibility to impart an auto-repair function to the epoxy matrix. The nanofiller has been covalently functionalized with hydrogen bonding moieties able to act as donor and acceptor of hydrogen bondings. Healing efficiencies have been evaluated for nano charged epoxy formulations at a loading of 0.5% wt/wt of functionalized MWCNTs bearing barbituric acid and thymine-based ligands. For both the performed functionalizations, a self-healing efficiency higher than 50% has been found. Dynamic Mechanical Analysis (DMA) highlights that the inclusion of nanofiller increases the storage moduli. Furthermore, DMA analysis evidences the presence of a phase characterized by a greater mobility of the epoxy chains, which promotes the activation of self-healing mechanisms.

Published
2018

15. 4D-Flussmessung in der kardialen MRT: Validierung bei Patienten mit angeborenem Herzfehler

Author

Binder, W, Hornung, A, Martirosian, P, Kramer, U, Schäfer, J, Hofbeck, M, and Sieverding, L

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Neben der Darstellung anatomischer Strukturen liegt eine Stärke der Kardio-MRT in der Funktionsanalyse des Herzens. Hierbei spielen Phasenkontrast-Flussmessungen eine große Rolle, die im Unterschied zur Echokardiographie auch die Quantifizierung von Flussvolumina ermöglichen.[zum vollständigen Text gelangen Sie über die oben angegebene URL], Süddeutscher Kongress für Kinder- und Jugendmedizin; 65. Jahrestagung der Süddeutschen Gesellschaft für Kinder- und Jugendmedizin gemeinsam mit der Süddeutschen Gesellschaft für Kinderchirurgie und dem Berufsverband der Kinder- und Jugendärzte e.V. – Landesverband Hessen

Published
2016
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16. Kardiale MRT bei Herzschrittmacherträgern?!

Author

Binder, W., Hornung, A., Frische, C., Kerst, G., Martirosian, P., Kramer, U., and Sieverding, L.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Fragestellung: Bis vor wenigen Jahren galt das Vorhandensein eines Herzschrittmachers als absolute Kontraindikation für die Durchführung einer Magnetresonanztomographie (MRT). Mittlerweile werden verschiedene MRT-taugliche Schrittmachersysteme angeboten. Auch bei diesen Systemen bestehen unter[zum vollständigen Text gelangen Sie über die oben angegebene URL], Süddeutscher Kongress für Kinder- und Jugendmedizin; 65. Jahrestagung der Süddeutschen Gesellschaft für Kinder- und Jugendmedizin gemeinsam mit der Süddeutschen Gesellschaft für Kinderchirurgie und dem Berufsverband der Kinder- und Jugendärzte e.V. – Landesverband Hessen

Published
2016

21. Supramolecular materials based on hydrogen-bonded polymers

Author

ten Brinke, Gerrit, Ruokolainen, Janne, Ikkala, Olli, Binder, W, and Polymer Chemistry and Bioengineering

Subjects
Materials science, ORDER-DISORDER TRANSITION, Supramolecular chemistry, Nanotechnology, Conductivity, LIQUID-CRYSTAL POLYMERS, POLYELECTROLYTE-SURFACTANT COMPLEXES, SIDE-CHAIN POLYMERS, Polymer chemistry, Copolymer, polymers, chemistry.chemical_classification, Hydrogen bond, responsivity, COMB-SHAPED SUPRAMOLECULES, ALTERNATING MULTILAYER FILM, Polymer, self-assembly, INDUCED MESOMORPHIC STRUCTURES, hydrogen bonding, Supramolecular polymers, block copolymers, chemistry, DIBLOCK COPOLYMER TEMPLATES, PSEUDO-BLOCK-COPOLYMERS, Self-assembly, tunability, END-FUNCTIONALIZED OLIGOMERS, Material properties
Abstract

Combining supramolecular principles with block copolymer self-assembly offers unique possibilities to create materials with responsive and/or tunable properties. The present chapter focuses on supramolecular materials based on hydrogen bonding and (block co-) polymers. Several cases will be discussed where the self-assembled nanostructured morphology can be easily tuned using composition as the natural variable. A large body of the material reviewed concerns hydrogen-bonded side-chain (block co-) polymers. Side chains both with and without mesogenic units are discussed. Frequently the thermoreversibility of the hydrogen bonds allows for responsiveness of material properties to external stimuli such as temperature, pH, and electromagnetic fields. Temperature-dependent photonic bandgap, temperature-dependent proton conductivity, pH-erasable multilayers, temperature-induced volume transitions, and fast AC electric field-induced orientational switching of microdomains are the main examples.

Published
2007

22. Kardiale MRT bei Herzschrittmacherträgern?!

Author

Binder, W, Hornung, A, Frische, C, Kerst, G, Martirosian, P, Kramer, U, Sieverding, L, Binder, W, Hornung, A, Frische, C, Kerst, G, Martirosian, P, Kramer, U, and Sieverding, L

Published
2016

25. HANDLING AND USES OF THE ALKALI METALS

Author

MARSHALL SITTIG, JOHN W. COLTON, H. C. MEYER, WALTER M. FENTON, DONALD L. ESMAY, RONALD L. LARSEN, HERBERT H. SCHROEDER, FREDERICK C. FOSTER, JOHN L. BINDER, W. H. HOWLAND, L. F. EPSTEIN, F. A. SMITH, J. F. CAGE, W. H. BRUGGEMAN, F. C. HANNY, H. F. KARNES, E. E. HOFFMAN, W. D. MANLY, D. D. ADAMS, G.

Published
1957

38. Evaluation of different immunoassays for the detection of antiphospholipid antibodies: Report of a wet workshop during the 13th International Congress on Antiphospholipid Antibodies

Author

Forastiero, R., primary, Papalardo, E., additional, Watkins, M., additional, Nguyen, H., additional, Quirbach, C., additional, Jaskal, K., additional, Kast, M., additional, Teodorescu, M., additional, Lakos, G., additional, Binder, W., additional, Shums, Z., additional, Nelson, V., additional, Norman, G., additional, Puig, J., additional, Cox, A., additional, Vandam, W., additional, Hardy, J., additional, and Pierangeli, S., additional

Published
2014
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40. Performance evaluation of a novel chemiluminescence assay for detection of anti-GBM antibodies: An international multicenter study

Author

Mahler, M, Radice, A, Sinico, R, Damoiseaux, J, Seaman, A, Buckmelter, K, Vizjak, A, Buchner, C, Binder, W, Fritzler, M, Cui, Z, Cui, Z., SINICO, RENATO ALBERTO, Mahler, M, Radice, A, Sinico, R, Damoiseaux, J, Seaman, A, Buckmelter, K, Vizjak, A, Buchner, C, Binder, W, Fritzler, M, Cui, Z, Cui, Z., and SINICO, RENATO ALBERTO

Abstract

Background.Autoantibodies to the non-collagen region (NC1) of the alpha-3 subunit of collagen IV represent a serological hallmark in the diagnosis of Goodpasture's syndrome (GPS). The objective of our study was to carefully analyze the performance characteristics of a novel anti-glomerular basement membrane (GBM) chemiluminescence immunoassay (CIA). Methods.Sera from patients with GPS (n = 90) were collected from four clinical centers. Samples from different disease groups (n = 397) and healthy individuals (n = 400) were used as controls. All samples were tested for anti-GBM antibodies by a rapid, random access CIA (QUANTA FlashTM GBM). Most of the samples were also tested using other methods including different commercial anti-GBM IgG assays and research assays for anti-GBM IgA and IgM. Results.The sensitivity and specificity of the novel CIA was 95.6% [95% confidence interval (CI) 89.0-98.8%] and 99.6% (95% CI 98.9-99.9%), respectively. Receiver operating characteristic analysis showed good discrimination between GPS patients and controls. The area under the curve was 0.98 (CI 0.96-1.0). The three anti-GBM antibody-positive samples from the control group were from two healthy individuals and one human immunodeficiency virus (HIV)-infected patient. All three individuals had low levels of anti-GBM antibodies [20, 24 and 25 chemiluminescent unit (CU), cutoff 20 CU]. When the results of the new CIA were compared to other methods, good agreement was observed: 95.8% (kappa = 0.92) versus EliATM GBM, 97.4% (kappa = 0.95) versus both BINDAZYMETM Anti-GBM and QUANTA Lite® GBM. Anti-GBM IgA was detectable in low concentrations in patients with GPS and was associated with anti-GBM IgG but was less useful in discriminating GPS patients and controls. No discrimination was found for anti-GBM IgM. Conclusion.The novel QUANTA FlashTM GBM CIA demonstrated good sensitivity and specificity and had good agreement with other methods. Our data confirm that ∼5% of patients with GPS do n

Published
2012

47. Anti- 2-glycoprotein I IgG antibodies from 1-year-old healthy children born to mothers with systemic autoimmune diseases preferentially target domain 4/5: might it be the reason for their 'innocent' profile?

Author

Andreoli, L., primary, Nalli, C., additional, Motta, M., additional, Norman, G. L., additional, Shums, Z., additional, Encabo, S., additional, Binder, W. L., additional, Nuzzo, M., additional, Frassi, M., additional, Lojacono, A., additional, Avcin, T., additional, Meroni, P.-L., additional, and Tincani, A., additional

Published
2010
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