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3. Problems With Temporary Cardiac Pacing

Author

Jefferson, Paul, Perkins, Vincent, Richardson, Tristan, Risebero, Sophie, Cormican, Liam, Baker, Emma, Clarke, Nigel, Davey, Patrick, Springings, David, and Birkhead, John

Published
2002

4. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Author

Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Najafov, Ruslan, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Sobhy, Mohamed, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, DʼAngeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, and Sokolov, Yuriy

Published
2014
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7. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries

Author

Widimsky, Petr, Wijns, William, Fajadet, Jean, de Belder, Mark, Knot, Jiri, Aaberge, Lars, Andrikopoulos, George, Baz, Jose Antonio, Betriu, Amadeo, Claeys, Marc, Danchin, Nicholas, Djambazov, Slaveyko, Erne, Paul, Hartikainen, Juha, Huber, Kurt, Kala, Petr, Klinčeva, Milka, Kristensen, Steen Dalby, Ludman, Peter, Ferre, Josephina Mauri, Merkely, Bela, Miličić, Davor, Morais, Joao, Noč, Marko, Opolski, Grzegorz, Ostojić, Miodrag, Radovanovič, Dragana, De Servi, Stefano, Stenestrand, Ulf, Studenčan, Martin, Tubaro, Marco, Vasiljević, Zorana, Weidinger, Franz, Witkowski, Adam, Zeymer, Uwe, Legrand, Victor, Velchev, Vasil, Heiztler, Vjeran Nikolić, Babić, Zdravko, Bergovec, Mijo, Žerjavić, Vlasta Hrabak, Kralj, Verica, Zelizko, Michael, Aschermann, Michael, Jansky, Petr, Tousek, Frantisek, Holm, Frantisek, Junker, Anders, Marandi, Toomas, Gilard, Martine, Blanchard, Didier, Schaechinger, Volker, Gitt, Anselm, Boehm, Michael, Papaioannou, Georgios, Becker, David, Battler, Alexander, Lewis, Basil, Behar, Shlomo, Erglis, Andrejs, Navickas, Ramunas, Koch, Karel T., ter Burg, Willem J., Polonski, Lech, Deleanu, Dan, Tatu-Chitoiu, Gabriel, Baráková, Anna, Hlava, Peter, Murín, Ján, Kamenský, Gabriel, Kaliská, Gabriela, Albarrang, Agustin, Hernandez, Felipe, Windecker, Stephan, Eeckhout, Eric, Kozan, Omer, Enar, Rasim, and Birkhead, John

Published
2010
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11. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Author

Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, Sokolov, Yuriy, Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, and Sokolov, Yuriy

Abstract

Aims Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged

Published
2017

14. Euro Heart Survey 2009 Snapshot:regional variations in presentation and management of patients with AMI in 47 countries

Author

Puymirat, Etienne, Battler, Alex, Birkhead, John, Bueno, Hector, Clemmensen, Peter, Cottin, Yves, Fox, Keith Aa, Gorenek, Bulent, Hamm, Christian, Huber, Kurt, Lettino, Maddalena, Lindahl, Bertil, Müller, Christian, Parkhomenko, Alexander, Price, Susanna, Quinn, Tom, Schiele, Francois, Simoons, Maarten, Tatu-Chitoiu, Gabriel, Tubaro, Marco, Vrints, Christiaan, Zahger, Doron, Zeymer, Uwe, Danchin, Nicolas, participants, EHS 2009 snapshot, Puymirat, Etienne, Battler, Alex, Birkhead, John, Bueno, Hector, Clemmensen, Peter, Cottin, Yves, Fox, Keith Aa, Gorenek, Bulent, Hamm, Christian, Huber, Kurt, Lettino, Maddalena, Lindahl, Bertil, Müller, Christian, Parkhomenko, Alexander, Price, Susanna, Quinn, Tom, Schiele, Francois, Simoons, Maarten, Tatu-Chitoiu, Gabriel, Tubaro, Marco, Vrints, Christiaan, Zahger, Doron, Zeymer, Uwe, Danchin, Nicolas, and participants, EHS 2009 snapshot

Published
2013

21. The effects of intravenous insulin infusions on early mortality for patients with acute coronary syndromes who present with hyperglycaemia: A matched propensity analysis using data from the MINAP database 2008–2012

Author

Birkhead, John, Weston, Clive, Timmis, Adam, and Chen, Ruoling

Abstract

Background: In acute coronary syndrome, the use of intravenous insulin infusions (IVII) to control hyperglycaemia is based on limited evidence of survival benefit.Aims: To compare 7 day survival for patients receiving IVII compared with those receiving routine care to control admission hyperglycaemia (>=11 mmol/l) in acute coronary syndrome.Methods and results: We used matched propensity analysis to examine observational data from the MINAP database between 2008 and 2012. We matched 5974 pairs of patients. We separately examined outcomes for ST elevation (STEMI) and non ST segment elevation (NSTEMI) infarctions, and those without known diabetes and those with type 2 diabetes. Survival benefit from the use of IVII was seen only in patients with STEMI not known to have diabetes at admission (adjusted hazard ratio (HR) 0.77 (95% confidence interval (CI) 0.64–0.92), p=0.005). Those with STEMI and existing type 2 diabetes who received IVII showed similar outcomes to routine care (HR 0.99 (95% CI 0.80–1.23), p=0.931). In patients with NSTEMI IVII was associated with significantly worse adjusted 7 day survival outcome than routine care, regardless of diabetes status; for those without known diabetes, HR 1.50 (95% CI 1.04–2.16), p=0.029, and for those with type 2 diabetes, HR 1.35 (95% CI 1.08–1.70), p=0.010.Conclusion: As used in current clinical practice to treat hyperglycaemia in acute coronary syndromes, IVII appears to be of benefit only for patients with STEMI who are not known to have diabetes. IVII is associated with adverse early outcomes in patients with NSTEMI.

Published
2015
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22. Euro Heart Survey 2009 Snapshot: regional variations in presentation and management of patients with AMI in 47 countries

Author

Puymirat, Etienne, Battler, Alex, Birkhead, John, Bueno, Hector, Clemmensen, Peter, Cottin, Yves, Fox, Keith AA, Gorenek, Bulent, Hamm, Christian, Huber, Kurt, Lettino, Maddalena, Lindahl, Bertil, Müller, Christian, Parkhomenko, Alexander, Price, Susanna, Quinn, Tom, Schiele, Francois, Simoons, Maarten, Tatu-Chitoiu, Gabriel, Tubaro, Marco, Vrints, Christiaan, Zahger, Doron, Zeymer, Uwe, and Danchin, Nicolas

Abstract

Aims: Detailed data on patients admitted for acute myocardial infarction (AMI) on a European-wide basis are lacking. The Euro Heart Survey 2009 Snapshot was designed to assess characteristics, management, and hospital outcomes of AMI patients throughout European Society of Cardiology (ESC) member countries in a contemporary ‘real-world’ setting, using a methodology designed to improve the representativeness of the survey.Methods: Member countries of the ESC were invited to participate in a 1-week survey of all patients admitted for documented AMI in December 2009. Data on baseline characteristics, type of AMI, management, and complications were recorded using a dedicated electronic form. In addition, we used data collected during the same time period in national registries in Sweden, England, and Wales. Data were centralized at the European Heart House.Results: Overall, 4236 patients (mean age 66±13 years; 31% women) were included in the study in 47 countries. Sixty per cent of patients had ST-segment elevation myocardial infarction, with 50% having primary percutaneous coronary intervention and 21% fibrinolysis. Aspirin and thienopyridines were used in >90%. Unfractionated and low-molecular-weight heparins were the most commonly used anticoagulants. Statins, beta-blockers, and angiotensin-converting enzyme inhibitors were used in >80% of the patients. In-hospital mortality was 6.2%. Regional differences were observed, both in terms of population characteristics, management, and outcomes.Conclusions: In-hospital mortality of patients admitted for AMI in Europe is low. Although regional variations exist in their presentation and management, differences are limited and have only moderate impact on early outcomes.

Published
2013
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23. Notes & Queries.

Author

Piggott, Lance, Brook, Stephen, MacDonogh, Giles, Raynor, M., Baxter, David, Birkhead, John, Harding, Julia, Longfield, Isabelle, Foster, George, Sabine, C., and Lees, Geoffrey

Published
2015

24. Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries

Author

Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, Sokolov, Yuriy, Kristensen, Steen D., Laut, Kristina G., Fajadet, Jean, Kaifoszova, Zuzana, Kala, Petr, Di Mario, Carlo, Wijns, William, Clemmensen, Peter, Agladze, Vaja, Antoniades, Loizos, Alhabib, Khalid F., De Boer, Menko-Jan, Claeys, Marc J., Deleanu, Dan, Dudek, Dariusz, Erglis, Andrejs, Gilard, Martine, Goktekin, Omer, Guagliumi, Giulio, Gudnason, Thorarinn, Hansen, Kim Wadt, Huber, Kurt, James, Stefan, Janota, Tomáš, Jennings, Siobhan, Kajander, Olli, Kanakakis, John, Karamfiloff, Kiril K., Kedev, Sasko, Kornowski, Ran, Ludman, Peter F., Merkely, Béla, Milicic, Davor, Najafov, Ruslan, Nicolini, Francesca A., Noč, Marko, Ostojic, Miodrag, Pereira, Hélder, Radovanovic, Dragana, Sabaté, Manel, Sobhy, Mohamed, Sokolov, Maxim, Studencan, Martin, Terzic, Ibrahim, Wahler, Steffen, Widimsky, Petr, Mühlberger, Volker, Legrand, V., Spuzic, M., Hajric, R., Markota, D., Srdic, S., Jorgova, Julia, Velchev, Vassil, Petrov, Ivo, Nikolic Heitzler, V., Babic, Z., Nicolaides, Evagoras, Christodulides, Theodoros, Georgiou, Panagiota, Jansky, Petr, Stasek, Josef, Terkelsen, Christian Juhl, Galatius, Søren, Sørensen, Rikke, Shal, Ahmed El, Romppanen, Hannu, Müller, Alfred, Rustige, Jörg, Alexopoulos, Dimitrios, Kallikazaros, Ioannis, Papaioannou, Georgios, Becker, David, Ungi, Imre, Kiss, Robert Gabor, Skuladottir, Frida Bjork, Bjornsdottir, Thora K., Cavanagh, Brendan, Twomey, Kathleen, Daly, Kieran, Matetzky, Shlomi, De Luca, Leonardo, Cremonesi, Alberto, Bovenzi, Francesco, Zakke, IIja, Maca, Aija, Narbute, Inga, Antov, S., Koch, Karel T., Mimoso, Jorge, Almeida, Manuel, Pereira, Ernesto, Tatu, Gabriel, Vinereanu, Dragos, D'Angeli, Cinzia, Nedeljkovic, Milan, Vukcevic, Vladan, Dobric, Milan, Hricak, V., Kovař, F., Kurray, P., Peral, Vincente, Tresserras, Ricard, Regueiro, Ander, Erne, Paul, Rickli, Hans, Windecker, Stephan, Kozan, Omer, Ertas, Gokhan, Kervan, Umit, Birkhead, John, and Sokolov, Yuriy

Abstract

Aims Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion therapy in ST-elevation myocardial infarction (STEMI). We conducted this study to evaluate the contemporary status on the use and type of reperfusion therapy in patients admitted with STEMI in the European Society of Cardiology (ESC) member countries. Methods and results A cross-sectional descriptive study based on aggregated country-level data on the use of reperfusion therapy in patients admitted with STEMI during 2010 or 2011. Thirty-seven ESC countries were able to provide data from existing national or regional registries. In countries where no such registries exist, data were based on best expert estimates. Data were collected on the use of STEMI reperfusion treatment and mortality, the numbers of cardiologists, and the availability of PPCI facilities in each country. Our survey provides a brief data summary of the degree of variation in reperfusion therapy across Europe. The number of PPCI procedures varied between countries, ranging from 23 to 884 per million inhabitants. Primary percutaneous coronary intervention and thrombolysis were the dominant reperfusion strategy in 33 and 4 countries, respectively. The mean population served by a single PPCI centre with a 24-h service 7 days a week ranged from 31 300 inhabitants per centre to 6 533 000 inhabitants per centre. Twenty-seven of the total 37 countries participated in a former survey from 2007, and major increases in PPCI utilization were observed in 13 of these countries. Conclusion Large variations in reperfusion treatment are still present across Europe. Countries in Eastern and Southern Europe reported that a substantial number of STEMI patients are not receiving any reperfusion therapy. Implementation of the best reperfusion therapy as recommended in the guidelines should be encouraged

29. Letters.

Author

Merwin, Charlie, Tissot, Matthieu, Jefferys, Richard, Birkhead, John, and Tye, James

Published
2017

30. National Audit of Myocardial Infarction (MINAP): a project in evolution

Author

Birkhead, John and Walker, Lynne

Abstract

The National Audit of Myocardial Infarction (MINAP) is a national online electronic reporting and analysis system developed to monitor the process of care of patients with acute coronary syndromes (Birkhead et al, 2002). This project differs from a simple prospective registry of coronary heart disease, as it is designed primarily to provide hospitals with continuously updated contemporary analyses of the care of their patients.

Published
2004
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31. Hospitals in UK meet targets on MI therapy.

Author

Birkhead, John

Abstract

Presents a letter to the editor in response to the article "Quality Results Patchy in 'Weary' Health Service," which focused on the treatment of myocardial infarction, published in the December 4, 2003 issue of "Hospital Doctor."

Published
2004

32. LETTERS.

Author

BIRKHEAD, JOHN, NICHOLSON Jr., ROLAND, DRIESEN, JENNIE, AL QUTOB, MUNJED FARID, ROSSBACH, ANN, SCHNEIDERMAN, JASON, FERRARO, MARIANNE, SCHREINER, PHOEBE, LEIBOWITZ, MATT, and MARTÍNEZ, HUGO

Subjects
*MASS murder, *RAPE prevention, *CLIMATE change
Abstract

Several letters to the editor are presented in response to articles in the previous issues including "Charleston Massacre Suspect Held as City Grieves" in the June 19, 2015 issue, "Pope Offers Radical Vision to Address Climate Change" in the June 19, 2015 issue, and "College Rape Prevention Program Proves a Rare Success" in the June 11, 2015 issue.

Published
2015

34. The effects of intravenous insulin infusions on early mortality for patients with acute coronary syndromes who present with hyperglycaemia: A matched propensity analysis using data from the MINAP database 2008-2012.

Author

Birkhead J, Weston C, Timmis A, and Chen R

Subjects
Aged, Aged, 80 and over, Female, Humans, Infusions, Intravenous, Insulin adverse effects, Male, Middle Aged, Observational Studies as Topic, Propensity Score, Registries, Survival Analysis, Treatment Outcome, Acute Coronary Syndrome mortality, Diabetes Mellitus, Type 2 drug therapy, Insulin administration & dosage, ST Elevation Myocardial Infarction mortality
Abstract

Background: In acute coronary syndrome, the use of intravenous insulin infusions (IVII) to control hyperglycaemia is based on limited evidence of survival benefit., Aims: To compare 7 day survival for patients receiving IVII compared with those receiving routine care to control admission hyperglycaemia (>=11 mmol/l) in acute coronary syndrome., Methods and Results: We used matched propensity analysis to examine observational data from the MINAP database between 2008 and 2012. We matched 5974 pairs of patients. We separately examined outcomes for ST elevation (STEMI) and non ST segment elevation (NSTEMI) infarctions, and those without known diabetes and those with type 2 diabetes. Survival benefit from the use of IVII was seen only in patients with STEMI not known to have diabetes at admission (adjusted hazard ratio (HR) 0.77 (95% confidence interval (CI) 0.64-0.92), p=0.005). Those with STEMI and existing type 2 diabetes who received IVII showed similar outcomes to routine care (HR 0.99 (95% CI 0.80-1.23), p=0.931). In patients with NSTEMI IVII was associated with significantly worse adjusted 7 day survival outcome than routine care, regardless of diabetes status; for those without known diabetes, HR 1.50 (95% CI 1.04-2.16), p=0.029, and for those with type 2 diabetes, HR 1.35 (95% CI 1.08-1.70), p=0.010., Conclusion: As used in current clinical practice to treat hyperglycaemia in acute coronary syndromes, IVII appears to be of benefit only for patients with STEMI who are not known to have diabetes. IVII is associated with adverse early outcomes in patients with NSTEMI., (© The European Society of Cardiology 2014.)

Published
2015
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35. Euro Heart Survey 2009 Snapshot: regional variations in presentation and management of patients with AMI in 47 countries.

Author

Puymirat E, Battler A, Birkhead J, Bueno H, Clemmensen P, Cottin Y, Fox KA, Gorenek B, Hamm C, Huber K, Lettino M, Lindahl B, Müller C, Parkhomenko A, Price S, Quinn T, Schiele F, Simoons M, Tatu-Chitoiu G, Tubaro M, Vrints C, Zahger D, Zeymer U, and Danchin N

Subjects
Aged, Female, Follow-Up Studies, Global Health, Humans, Male, Morbidity trends, Prospective Studies, Survival Rate trends, Disease Management, Myocardial Infarction epidemiology, Myocardial Infarction therapy, Outcome Assessment, Health Care methods, Population Surveillance methods, Registries
Abstract

Aims: Detailed data on patients admitted for acute myocardial infarction (AMI) on a European-wide basis are lacking. The Euro Heart Survey 2009 Snapshot was designed to assess characteristics, management, and hospital outcomes of AMI patients throughout European Society of Cardiology (ESC) member countries in a contemporary 'real-world' setting, using a methodology designed to improve the representativeness of the survey., Methods: Member countries of the ESC were invited to participate in a 1-week survey of all patients admitted for documented AMI in December 2009. Data on baseline characteristics, type of AMI, management, and complications were recorded using a dedicated electronic form. In addition, we used data collected during the same time period in national registries in Sweden, England, and Wales. Data were centralized at the European Heart House., Results: Overall, 4236 patients (mean age 66±13 years; 31% women) were included in the study in 47 countries. Sixty per cent of patients had ST-segment elevation myocardial infarction, with 50% having primary percutaneous coronary intervention and 21% fibrinolysis. Aspirin and thienopyridines were used in >90%. Unfractionated and low-molecular-weight heparins were the most commonly used anticoagulants. Statins, beta-blockers, and angiotensin-converting enzyme inhibitors were used in >80% of the patients. In-hospital mortality was 6.2%. Regional differences were observed, both in terms of population characteristics, management, and outcomes., Conclusions: In-hospital mortality of patients admitted for AMI in Europe is low. Although regional variations exist in their presentation and management, differences are limited and have only moderate impact on early outcomes.

Published
2013
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