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4. Human Neonatal Rotavirus Vaccine (RV3-BB) to Target Rotavirus from Birth

Author

Bines, Julie E., At Thobari, Jarir, Satria, Cahya Dewi, Handley, Amanda, Watts, Emma, Cowley, Daniel, Nirwati, Hera, Ackland, James, Standish, Jane, Justice, Frances, Byars, Gabrielle, Lee, Katherine J., Barnes, Graeme L., Bachtiar, Novilia S., Icanervilia, Ajeng Viska, Boniface, Karen, Bogdanovic-Sakran, Nada, Pavlic, Daniel, Bishop, Ruth F., Kirkwood, Carl D., Buttery, Jim P., and Soenarto, Yati

Published
2018
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15. Cost effectiveness of rotavirus vaccination in Australia

Author

Carlin, John B., Jackson, Terri, Lane, Lisa, Bishop, Ruth F., and Barnes, Graeme L.

Subjects
Rotavirus infections -- Prevention, Vaccination of children -- Economic aspects, Health
Abstract

Objective: Rotavirus gastroenteritis causes substantial morbidity, including hospital admission, in young children. In the context of recent vaccine developments, this study aimed to estimate the cost-effectiveness of a rotavirus vaccination program in Australia. Method: Standard methods of health economic evaluation were used to assess the total cost of rotavirus immunisation (as the difference between estimated vaccination program costs and the cost of disease that would be avoided by immunisation) and relate this to the number of cases of disease that would be prevented. Estimates were made from both societal and health care systems perspectives. Results: Based on Australian data on disease incidence and cost of hospitalisation, the current annual cost of rotavirus disease is about $26.0 million. Using conservative vaccine efficacy estimates, current immunisation uptake rates and a cost of $30 per dose of vaccine, rotavirus immunisation would incur a net societal cost of $2.9 million ($11 per child), at a gross program cost of $21.6 million. These estimates are sensitive to two sources of uncertainty in the estimation of program delivery costs: vaccine price and whether separate immunisation visits would be required. Conclusion: A rotavirus immunisation program would be cost-neutral to Australian society at a vaccine price of $26 per dose (or $19 when health care system costs only are considered). Implications: Rotavirus immunisation may be cost-effective in Australia, but considerable uncertainty remains. Policy decisions will depend heavily on pricing of the vaccine and may also need to consider intangible costs not accounted for in this analysis.

Published
1999

24. Rotavirus gastroenteritis: impact on young children, their families and the health care system

Author

Liddle, Jeannine L.M., Burgess, Margaret A., Gilbert, Gwendolyn L., Hanson, Ralph M., McIntyre, Peter B., Bishop, Ruth F., and Ferson, Mark J.

Subjects
Physicians (General practice) -- Practice, Family medicine -- Practice, Rotavirus infections -- Economic aspects, Immunization -- Economic aspects, Gastroenteritis in children -- Economic aspects, Medical care -- Economic aspects, Diarrhea in children -- Prevention, Health
Abstract

Rotavirus gastroenteritis and its impact on the Australian healthcare system and on young children and their families are discussed based on a cross-sectional descriptive survey involving 280 children under three years of age presenting with acute diarrhea at an emergency department of a large-city children's hospital. Findings indicate rotavirus gastroenteritis has significant economic impact on young children, their families and the healthcare system and routine infant vaccination would potentially be cost-effective.

Published
1997

29. ENTERIC VIRUSES

Author

Bishop, Ruth F.

Subjects
Article
Published
2004

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