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4. Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract

Author

Frank, Thomas, Janssen, Marlies, Netzel, Michael, Strass, Gabriele, Kler, Adolf, Kriesl, Erwin, and Bitsch, Irmgard

Subjects
Medicine, Botanic -- Health aspects -- Nutritional aspects, Hibiscus -- Nutritional aspects -- Health aspects, Anthocyanin -- Health aspects -- Nutritional aspects, Medicine, Herbal -- Health aspects -- Nutritional aspects, Health, Nutritional aspects, Health aspects
Abstract

Pharmacokinetic parameters of several dietary anthocyanins following consumption of Hibiscus sabdariffa L. extract were determined in 6 healthy volunteers. Subjects were given a single oral dose of 150 mL of [...]

Published
2005

12. Lebensmittel - Grundlage der Ernährung

Author

Bitsch, Irmgard, Fortmann,Bettina, Klapp-Kunsemüller, Eva, Netzel, Michael, Shahrzad, Siranoush, Steinmetz, Thomas, Wenisch, Sabine, Ziems, Michaela, and Institut für Ernährungswissenschaft

Subjects
ddc:640, Home economics & family living
Published
1996

26. Intrauterine Vitamin B2Uptake of Preterm and Full-Term Infants

Author

Zempleni, Janos, Link, Gerold, and Bitsch, Irmgard

Abstract

Intrauterine uptake of vitamin B2in preterm and full-term infants was examined. Factors of influence on vitamin supply were considered. Forty-four women and their infants were included in the study. Fetal vitamin uptake was calculated as arteriovenous concentration gradient in cord plasma times umbilical plasma flow. Concentration of vitamin B2(free riboflavin and flavocoenzymes) was determined by high performance liquid chromatography of placental tissue and blood plasma (maternal vein, umbilical artery, umbilical vein). Flavocoenzymes were analyzed as flavin mononucleotide after acid hydrolysis of flavin adenine dinucleotide. Umbilical plasma flow was measured using pulsed Doppler sonography. Both free riboflavin and flavocoenzymes were transferred from the maternal plasma to the umbilical vein, but only free riboflavin was accumulated (~1:4 for preterm and full-term infants, respectively). Flavocoenzyme concentration was higher in the umbilical vein than in the umbilical artery (p < 0.05). This indicated a median uptake of flavocoenzymes of 1.5 nmol/min-kg in preterm infants and 0.4 nmol/ min-kg in full-term infants (preterm versus full-term, p < 0.01). Fetal vitamin supply depended on umbilical plasma flow and on maternal vitamin status (the latter was shown only in full-term infants). No dependence on placental vitamin concentration was observed (p > 0.05). Concentration of free riboflavin was higher in umbilical artery than in umbilical vein (p < 0.05). This indicated a release of free riboflavin from fetal tissues independent of gestational age (0.4 nmol/murkg, preterm; 0.2 nmol/ min-kg, full-term; p > 0.05).

Published
1995
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