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898 results on '"Bogers, Ad J.J.C."'

17. Long-term surgical outcomes of congenital supravalvular aortic stenosis:a systematic review, meta-analysis and microsimulation study

Author

Meccanici, Frederike, Notenboom, Maximiliaan L., Meijssen, Jade, Smit, Vernon, Van De Woestijne, Pieter C., Van Den Bosch, Annemien E., Helbing, Willem A., Bogers, Ad J.J.C., Takkenberg, Johanna J.M., Roos-Hesselink, Jolien W., Meccanici, Frederike, Notenboom, Maximiliaan L., Meijssen, Jade, Smit, Vernon, Van De Woestijne, Pieter C., Van Den Bosch, Annemien E., Helbing, Willem A., Bogers, Ad J.J.C., Takkenberg, Johanna J.M., and Roos-Hesselink, Jolien W.

Abstract

OBJECTIVES: Congenital supravalvular aortic stenosis (SVAS) is a rare form of congenital outflow tract obstruction and long-term outcomes are scarcely reported. This study aims to provide an overview of outcomes after surgical repair for congenital SVAS. METHODS: A systematic review of published literature was conducted, including observational studies reporting long-term clinical outcome (>2 years) after SVAS repair in children or adults considering >20 patients. Early risks, late event rates and time-to-event data were pooled and entered into a microsimulation model to estimate 30-year outcomes. Life expectancy was compared to the age-, sex- and origin-matched general population. RESULTS: Twenty-three publications were included, encompassing a total of 1472 patients (13 125 patient-years; pooled mean follow-up: 9.0 (6.2) years; median follow-up: 6.3 years). Pooled mean age at surgical repair was 4.7 (5.8) years and the most commonly used surgical technique was the single-patch repair (43.6%). Pooled early mortality was 4.2% (95% confidence interval: 3.2-5.5%) and late mortality was 0.61% (95% CI: 0.45-0.83) per patient-year. Based on microsimulation, over a 30-year time horizon, it was estimated that an average patient with SVAS repair (mean age: 4.7 years) had an observed life expectancy that was 90.7% (95% credible interval: 90.0-91.6%) of expected life expectancy in the matched general population. The microsimulation-based 30-year risk of myocardial infarction was 8.1% (95% credible interval: 7.3-9.9%) and reintervention 31.3% (95% credible interval: 29.6-33.4%), of which 27.2% (95% credible interval: 25.8-29.1) due to repair dysfunction. CONCLUSIONS: After surgical repair for SVAS, 30-year survival is lower than the matched-general-population survival and the lifetime risk of reintervention is considerable. Therefore, lifelong monitoring of the cardiovascular system and in particular residual stenosis and coronary obstruction is recommended.

Published
2024

18. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial

Author

Intensive care patientenzorg, Cluster A, Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, Wildschut, Enno D., Intensive care patientenzorg, Cluster A, Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, and Wildschut, Enno D.

Published
2024

19. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery:a multi-center randomized controlled trial

Author

Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, Wildschut, Enno D., Zeilmaker-Roest, Gerdien, de Vries-Rink, Christine, van Rosmalen, Joost, van Dijk, Monique, de Wildt, Saskia N., Knibbe, Catherijne A.J., Koomen, Erik, Jansen, Nicolaas J.G., Kneyber, Martin C.J., Maebe, Sofie, Van den Berghe, Greet, Haghedooren, Renata, Vlasselaers, Dirk, Bogers, Ad J.J.C., Tibboel, Dick, and Wildschut, Enno D.

Abstract

Background: To determine whether intermittent intravenous (IV) paracetamol as primary analgesic would significantly reduce morphine consumption in children aged 0–3 years after cardiac surgery with cardiopulmonary bypass. Methods: Multi-center, randomized, double-blinded, controlled trial in four level-3 Pediatric Intensive Care Units (PICU) in the Netherlands and Belgium. Inclusion period; March 2016–July 2020. Children aged 0–3 years, undergoing cardiac surgery with cardiopulmonary bypass were eligible. Patients were randomized to continuous morphine or intermittent IV paracetamol as primary analgesic after a loading dose of 100 mcg/kg morphine was administered at the end of surgery. Rescue morphine was given if numeric rating scale (NRS) pain scores exceeded predetermined cutoff values. Primary outcome was median weight-adjusted cumulative morphine dose in mcg/kg in the first 48 h postoperative. For the comparison of the primary outcome between groups, the nonparametric Van Elteren test with stratification by center was used. For comparison of the proportion of patients with one or more NRS pain scores of 4 and higher between the two groups, a non-inferiority analysis was performed using a non-inferiority margin of 20%. Results:In total, 828 were screened and finally 208 patients were included; parents of 315 patients did not give consent and 305 were excluded for various reasons. Fourteen of the enrolled 208 children were withdrawn from the study before start of study medication leaving 194 patients for final analysis. One hundred and two patients received intermittent IV paracetamol, 106 received continuous morphine. The median weight-adjusted cumulative morphine consumption in the first 48 h postoperative in the IV paracetamol group was 5 times lower (79%) than that in the morphine group (median, 145.0 (IQR, 115.0–432.5) mcg/kg vs 692.6 (IQR, 532.7–856.1) mcg/kg; P < 0.001). The rescue morphine cons

Published
2024

30. Intermittent intravenous paracetamol versus continuous morphine in infants undergoing cardiothoracic surgery: a multi-center randomized controlled trial

Author

Zeilmaker-Roest, Gerdien, primary, de Vries-Rink, Christine, additional, Rosmalen, Joost van, additional, Dijk, Monique van, additional, de Wildt, Saskia N., additional, Knibbe, Catherijne A. J., additional, Koomen, Erik, additional, Jansen, Nicolaas J. G., additional, Kneyber, Martin C. J., additional, Maebe, Sofie, additional, Berghe, Greet van den, additional, Haghedooren, Renata, additional, Vlasselaers, Dirk, additional, Bogers, Ad J.J.C., additional, Tibboel, Dick, additional, and Wildschut, Enno D., additional

Published
2024
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32. Translobar venous drainage management in (sub)lobar resections

Author

Bakhuis, Wouter, Betser, Lea, Sadeghi, Amir H., Gossot, Dominique, Susa, Denis, Maat, Alexander P.W.M., Siregar, Sabrina, Bogers, Ad J.J.C., Seguin-Givelet, Agathe, Mahtab, Edris A.F., and Cardiothoracic Surgery

Subjects
Pulmonary and Respiratory Medicine, Surgery
Published
2023

38. Long term outcome after surgical ASD-closure at young age: Longitudinal follow-up up to 50 years after surgery

Author

Kauling, Robert M., primary, Pelosi, Chiara, additional, Cuypers, Judith A.A.E., additional, van den Bosch, Annemien E., additional, Hirsch, Alexander, additional, Carvalho, João G., additional, Bowen, Daniel J., additional, Kardys, Isabella, additional, Bogers, Ad J.J.C., additional, Helbing, Wim A., additional, and Roos-Hesselink, Jolien W., additional

Published
2023
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