142 results on '"Bogossian H"'
Search Results
2. Sachkunde ICD-Therapie
- Author
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Eckardt, L., Sommer, P., Bogossian, H., Butter, C., Hansen, C., Steven, D., Tilz, R., Veltmann, C., and Böcker, D.
- Published
- 2021
- Full Text
- View/download PDF
3. Akute Bradykardien
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Hasan, F., Bogossian, H., and Lemke, B.
- Published
- 2020
- Full Text
- View/download PDF
4. Notfallmanagement supraventrikulärer regelmäßiger Tachykardien
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Höltgen, R., Bandorski, D., Bogossian, H., Brück, M., and Wieczorek, M.
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- 2020
- Full Text
- View/download PDF
5. Tachykardien bei pulmonalarterieller Hypertonie
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Bandorski, D., Bogossian, H., Ghofrani, A., Schmitt, J., and Höltgen, R.
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- 2020
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6. Application of the Bogossian formula for evaluation of the QT interval in pacemaker patients with stimulated left bundle branch block
- Author
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Weipert, K. F., Bogossian, H., Conzen, P., Frommeyer, G., Gemein, C., Helmig, I., Chasan, R., Eckardt, L., Seyfarth, M., Lemke, B., Zarse, M., Hamm, C. W., Schmitt, J., and Erkapic, D.
- Published
- 2018
- Full Text
- View/download PDF
7. Expertise in ICD therapy
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Eckardt, L., Sommer, P., Bogossian, H., Butter, C., Hansen, C., Steven, D., Tilz, R., Veltmann, C., Bocker, D., Eckardt, L., Sommer, P., Bogossian, H., Butter, C., Hansen, C., Steven, D., Tilz, R., Veltmann, C., and Bocker, D.
- Abstract
The use of active implants is regulated in Germany by law and the associated ordinances. Medical devices may only be operated or used by people who have the necessary training and experience. This means that physicians who use implantable cardioverter defibrillator (ICD) treatment need to acquire basic technical knowledge in addition to in-depth knowledge of rhythmology. This expertise in ICD treatment summarizes the contents for acquiring the necessary expertise and the theoretical knowledge imparted. The expertise covers new techniques, such as the subcutaneous ICD as well as the current guidelines, new studies on the indications and studies on intraoperative testing and programming recommendations. In the follow-up care, particular attention is paid to telemedical aspects and the legal basis as well as the current study situation. Together with the practical experience gained in clinical training and further education, the contents presented are the prerequisite for high-quality ICD treatment.
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- 2021
8. Do induced tachycardias within the scope of electrophysiological studies lead to elevated plasma troponin I levels?
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Bandorski, D., Bogossian, H., Lemke, B., Höltgen, R., Wieczorek, M., and Brück, M.
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- 2011
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9. Impending total AV-block in chronic bifascicular block -Risk assessment via symptoms and 12 lead ECG
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Zarse, M., Goebbert, K., Bogossian, H., Karossiene, Z., Stegelmeyer, J., Ninios, I., Kloppe, A., and Lemke, B.
- Published
- 2011
10. The transseptal acces increases safety and efficacy of substrate modification for ventricular tachycardia
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Zarse, M., Suleimann, H., Bogossian, H., Stegelmeyer, J., Ninios, I., Karosienne, Z., Kloppe, A., and Lemke, B.
- Published
- 2011
11. A new combined stylet/guide wire-tool for left ventricular lead placement for cardiac resynchronisation therapy
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Kloppe, A., Mijic, D., Bogossian, H., Ninios, I., Zarse, M., and Lemke, B.
- Published
- 2011
12. Long-term follow-up of single coil right ventricular ICD electrodes in high septal, mid septal and apical position: An evaluation in 293 patients
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Kloppe, A., Mijic, D., Bogossian, H., Zarse, M., and Lemke, B.
- Published
- 2011
13. P1133Acute and longterm safety of cephalic vein access for CRT-D implantation in comparison to subclavian vein access
- Author
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Kloppe, A, primary, Schiedat, F, additional, Kolbe, J, additional, Zimmermann, A, additional, Bogossian, H, additional, Zarse, M, additional, Mijic, D, additional, Karosiene, Z, additional, Muegge, A, additional, and Lemke, B, additional
- Published
- 2018
- Full Text
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14. P806Real World Data: Improvement of echocardiographic parameters, response and quality of life to Cardiac Resynchronization Therapy (CRT) continues up to 12 months after implantation
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Schiedat, F, primary, Kloppe, A, additional, Kolbe, J, additional, Zimmermann, A, additional, Bogossian, H, additional, Zarse, M, additional, Mijic, D, additional, Karosiene, Z, additional, Muegge, A, additional, and Lemke, B, additional
- Published
- 2018
- Full Text
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15. 1075Single chamber implantable cardioverter defibrillator compared to dual chamber implantable cardioverter defibrillator. Less is more. Data from the German Device Registry
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Bogossian, H, primary, Hochadel, M, additional, Ince, H, additional, Spitzer, S G, additional, Eckardt, L, additional, Maier, S, additional, Kleemann, T, additional, Brachmann, J, additional, Stellbrink, C, additional, Gonska, B D, additional, Kaab, S, additional, Senges, J, additional, and Lemke, B, additional
- Published
- 2018
- Full Text
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16. Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: Insights from the first prospective population-based study in rural Greece
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Ninios, I. Bogossian, H. Zarse, M. Lazaridou, F. Dimitriadis, K. Ninios, V. Lemke, B. Louridas, G.
- Abstract
To investigate the prevalence of permanent atrial fibrillation (AF), its clinical associated conditions and treatment status in the elderly population in rural Greece. 720 people (46.1% males) older than 65 years (mean age: 72.5 ± 5.7 years) living in four villages in rural Greece were screened with an electrocardiogram (response rate: 90.5%) for the presence of permanent AF. They underwent a physical examination, including blood pressure (BP) measurement, and body mass index (BMI) calculation, in addition to an interview about their medical history, physical activity, smoking habits, alcohol consumption and medication use. Subjects with AF for whom anticoagulants were contraindicated were identified and stroke risk stratification was performed using the CHADS2 algorithm. The prevalence of permanent AF was 5% (6.6% among men and 3.6% among women) and it increased with age. In the entire population, ECG evidence of myocardial ischaemia and ventricular premature beats were independently associated with the presence of permanent AF (OR 5.266; 95% CI 2.22-12.49, P = 0.0001 and OR 2.61; 95% CI 1.059-6.432, P = 0.037, respectively), while female sex was independently associated with the absence of the AF (OR 0.327; CI 0.147-0.729, P = 0.006). From those patients who were eligible for anticoagulation, 40.6% were treated with anticoagulants, 34.3% were given antiplatelets therapy and the rest received no antithrombotic treatment. This is the first prospective study demonstrating the prevalence, clinical correlates and treatment status of permanent AF in Greece. These results confirm the high prevalence of permanent AF among the elderly and underscore the issue regarding anticoagulants underutilization. © 2009 Springer Science+Business Media, LLC.
- Published
- 2010
17. Poster Session 3
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Fabbri, G. M. T., primary, Baldasseroni, S., additional, Panuccio, D., additional, Zoni Berisso, M., additional, Scherillo, M., additional, Lucci, D., additional, Di Pasquale, G., additional, Mathieu, G., additional, Burazor, I., additional, Burazor, M., additional, Perisic, Z., additional, Atanaskovic, V., additional, Erakovic, V., additional, Stojkovic, A., additional, Vogtmann, T., additional, Schoebel, C., additional, Sogorski, S., additional, Sebert, M., additional, Schaarschmidt, J., additional, Fietze, I., additional, Baumann, G., additional, Penzel, T., additional, Mornos, C., additional, Ionac, A., additional, Cozma, D., additional, Dragulescu, D., additional, Mornos, A., additional, Petrescu, L., additional, Pescariu, L., additional, Brembilla-Perrot, B., additional, Khachab, H., additional, Lamberti, F., additional, Bellini, C., additional, Remoli, R., additional, Cogliandro, T., additional, Nardo, R., additional, Bellusci, F., additional, Mazzuca, V., additional, Gaspardone, A., additional, Aguinaga Arrascue, L. E., additional, Bravo, A., additional, Garcia Freire, P., additional, Gallardo, P., additional, Hasbani, E., additional, Quintana, R., additional, Dantur, J., additional, Inoue, K., additional, Ueoka, A., additional, Tsubakimoto, Y., additional, Sakatani, T., additional, Matsuo, A., additional, Fujita, H., additional, Kitamura, M., additional, Wegrzynowska, M., additional, Konduracka, E., additional, Pietrucha, A. Z., additional, Mroczek-Czernecka, D., additional, Paradowski, A., additional, Bzukala, I., additional, Nessler, J., additional, Igawa, O., additional, Adachi, M., additional, Atarashi, H., additional, Kusama, Y., additional, Kodani, E., additional, Okazaki, R., additional, Nakagomi, A., additional, Endoh, Y., additional, Baez-Escudero, J. L., additional, Dave, A. S., additional, Sasaridis, C. M., additional, Valderrabano, M., additional, Tilz, R., additional, Bai, R., additional, Di Biase, L., additional, Gallinghouse, G. J., additional, Gibson, D., additional, Pisapia, A., additional, Wazni, O., additional, Natale, A., additional, Arujuna, A., additional, Karim, R., additional, Rinaldi, A., additional, Cooklin, M., additional, Rhode, K., additional, Razavi, R., additional, O'neill, M., additional, Gill, J., additional, Kusa, S., additional, Komatsu, Y., additional, Kakita, K., additional, Takayama, K., additional, Taniguchi, H., additional, Otomo, K., additional, Iesaka, Y., additional, Ammar, S., additional, Reents, T., additional, Fichtner, S., additional, Wu, J., additional, Zhu, P., additional, Kolb, C., additional, Hessling, G., additional, Deisenhofer, I., additional, Gilbert, G., additional, Mohanty, P., additional, Cunningham, J., additional, Metz, T., additional, Horton, R., additional, Tao, S., additional, Yamauchi, Y., additional, Okada, H., additional, Maeda, S., additional, Obayashi, T., additional, Isobe, M., additional, Chan, J., additional, Johar, S., additional, Wong, T., additional, Markides, V., additional, Hussain, W., additional, Konstantinidou, M., additional, Wissner, E., additional, Fuernkranz, A., additional, Yoshiga, Y., additional, Metzner, A., additional, Kuck, K.- H., additional, Ouyang, F., additional, Kettering, K., additional, Gramley, F., additional, Mollnau, H., additional, Weiss, C., additional, Bardeleben, S., additional, Biasco, L., additional, Scaglione, M., additional, Caponi, D., additional, Di Donna, P., additional, Sergi, D., additional, Cerrato, N., additional, Blandino, A., additional, Gaita, F., additional, Fiala, M., additional, Wichterle, D., additional, Sknouril, L., additional, Bulkova, V., additional, Chovancik, J., additional, Nevralova, R., additional, Pindor, J., additional, Januska, J., additional, Choi, J. I., additional, Ban, J. E., additional, Yasutsugu, N., additional, Park, J. S., additional, Jung, J. S., additional, Lim, H. E., additional, Park, S. W., additional, Kim, Y. H., additional, Kuhne, M., additional, Reichlin, T., additional, Ammann, P., additional, Schaer, B., additional, Osswald, S., additional, Sticherling, C., additional, Ohe, M., additional, Goya, M., additional, Hiroshima, K., additional, Hayashi, K., additional, Makihara, Y., additional, Nagashima, M., additional, Fukunaga, M., additional, An, Y., additional, Dorwarth, U., additional, Schmidt, M., additional, Wankerl, M., additional, Krieg, J., additional, Straube, F., additional, Hoffmann, E., additional, Kathan, S., additional, Defaye, P., additional, Mbaye, A., additional, Cassagneau, R., additional, Gagniere, V., additional, Jacon, P., additional, Pokushalov, E., additional, Romanov, A., additional, Artemenko, S., additional, Shabanov, V., additional, Elesin, D., additional, Stenin, I., additional, Turov, A., additional, Losik, D., additional, Kondo, K., additional, Miake, J., additional, Yano, A., additional, Ogura, K., additional, Kato, M., additional, Shigemasa, C., additional, Sekiguchi, Y., additional, Tada, H., additional, Yoshida, K., additional, Naruse, Y., additional, Yamasaki, H., additional, Igarashi, M., additional, Machino, T., additional, Aonuma, K., additional, Chen, S., additional, Liu, S., additional, Chen, G., additional, Meng, W., additional, Zhang, F., additional, Yan, Y., additional, Sciarra, L., additional, Dottori, S., additional, Lanzillo, C., additional, De Ruvo, E., additional, De Luca, L., additional, Minati, M., additional, Lioy, E., additional, Calo', L., additional, Lin, J., additional, Nie, Z., additional, Zhu, M., additional, Wang, X., additional, Zhao, J., additional, Hu, W., additional, Tao, H., additional, Ge, J., additional, Johansson, B., additional, Houltz, B., additional, Edvardsson, N., additional, Schersten, H., additional, Karlsson, T., additional, Wandt, B., additional, Berglin, E., additional, Hoyt, R. H., additional, Jenson, B. P., additional, Trines, S. A. I. P., additional, Braun, J., additional, Tjon Joek Tjien, A., additional, Zeppenfeld, K., additional, Tavilla, G., additional, Klautz, R. J. M., additional, Schalij, M. J., additional, Krausova, R., additional, Cihak, R., additional, Peichl, P., additional, Kautzner, J., additional, Pirk, J., additional, Skalsky, I., additional, Maly, J., additional, Imai, K., additional, Sueda, T., additional, Orihashi, K., additional, Picarra, B. C., additional, Santos, A. R., additional, Dionisio, P., additional, Semedo, P., additional, Matos, R., additional, Leitao, M., additional, Banha, M., additional, Trinca, M., additional, Elder, D. H. J., additional, George, J., additional, Jain, R., additional, Lang, C. C., additional, Choy, A. M., additional, Konert, M., additional, Loescher, S., additional, Hartmann, A., additional, Aversa, E., additional, Chirife, R., additional, Sztyglic, E., additional, Mazzetti, H., additional, Mascheroni, O., additional, Tentori, M. C., additional, Pop, R. M., additional, Margulescu, A. D., additional, Dulgheru, R., additional, Enescu, O., additional, Siliste, C., additional, Vinereanu, D., additional, Menezes Junior, A., additional, Castro Carneiro, A. R., additional, De Oliveira, B. L., additional, Shah, A. N., additional, Kantharia, B., additional, De Lucia, R., additional, Soldati, E., additional, Segreti, L., additional, Di Cori, A., additional, Zucchelli, G., additional, Viani, S., additional, Paperini, L., additional, Bongiorni, M. G., additional, Kutarski, A., additional, Czajkowski, M., additional, Pietura, R., additional, Malecka, B., additional, Heintze, J., additional, Eckardt, L., additional, Bauer, A., additional, Meine, M., additional, Van Erven, L., additional, Bloch Thomsen, P. E., additional, Lopez Chicharro, M. P., additional, Merhi, O., additional, Soga, Y., additional, Andou, K., additional, Nobuyoshi, M., additional, Gonzalez-Mansilla, A., additional, Martin-Asenjo, R., additional, Unzue, L., additional, Torres, J., additional, Garralda, E., additional, Coma, R. R., additional, Rodriguez Garcia, J. E., additional, Yaegashi, T., additional, Furusho, H., additional, Kato, T., additional, Chikata, A., additional, Takashima, S., additional, Usui, S., additional, Takamura, M., additional, Kaneko, S., additional, Chudzik, M., additional, Mitkowski, P., additional, Przybylski, A., additional, Lewek, J., additional, Smukowski, T., additional, Maciag, A., additional, Castrejon Castrejon, S., additional, Perez-Silva, A., additional, Estrada, A., additional, Doiny, D., additional, Ortega, M., additional, Lopez-Sendon, J. L., additional, Merino, J. L., additional, O'mahony, C., additional, Coats, C., additional, Cardona, M., additional, Garcia, A., additional, Calcagnino, M., additional, Lachmann, R., additional, Hughes, D., additional, Elliott, P. M., additional, Conti, S., additional, Pruiti, G. P., additional, Puzzangara, E., additional, Romano, S. A., additional, Di Grazia, A., additional, Ussia, G. P., additional, Tamburino, C., additional, Calvi, V., additional, Radinovic, A., additional, Sala, S., additional, Latib, A., additional, Mussardo, M., additional, Sora, S., additional, Paglino, G., additional, Gullace, M., additional, Colombo, A., additional, Ohlow, M.- A. G., additional, Lauer, B., additional, Wagner, A., additional, Schreiber, M., additional, Buchter, B., additional, Farah, A., additional, Fuhrmann, J. T., additional, Geller, J. C., additional, Nascimento Cardoso, R. M., additional, Batista Sa, L. A., additional, Campos Filho, L. F. C., additional, Rodrigues, S. V., additional, Dutra, M. V. F., additional, Borges, T. R. S. A., additional, Portilho, D. R., additional, Deering, T., additional, Bernardes, A., additional, Veiga, A., additional, Gartenlaub, O., additional, Goncalves, A., additional, Jimenez, A., additional, Rousseauplasse, A., additional, Deharo, J. C., additional, Striekwold, H., additional, Gosselin, G., additional, Sitbon, H., additional, Martins, V., additional, Molon, G., additional, Ayala-Paredes, F., additional, Sancho-Tello, M. J., additional, Fazal, I. A., additional, Brady, S., additional, Cronin, J., additional, Mcnally, S., additional, Tynan, M., additional, Plummer, C. J., additional, Mccomb, J. M., additional, Val-Mejias, J. E., additional, Oliveira, R. M., additional, Costa, R., additional, Martinelli Filho, M., additional, Silva, K. R., additional, Menezes, L. M., additional, Tamaki, W. T., additional, Mathias, W., additional, Stolf, N. A. G., additional, Misawa, T., additional, Ohta, I., additional, Shishido, T., additional, Miyasita, T., additional, Miyamoto, T., additional, Nitobe, J., additional, Watanabe, T., additional, Kubota, I., additional, Thibault, B., additional, Ducharme, A., additional, Simpson, C., additional, Stuglin, C., additional, Gagne, C. E., additional, Williams, R., additional, Mcnicoll, S., additional, Silvetti, M. S., additional, Drago, F., additional, Penela, D., additional, Bijnens, B., additional, Doltra, A., additional, Silva, E., additional, Berruezo, A., additional, Mont, L., additional, Sitges, M., additional, Mcintosh, R., additional, Baumann, O., additional, Raju, P., additional, Gurunathan, S., additional, Furniss, S., additional, Patel, N., additional, Sulke, N., additional, Lloyd, G., additional, Mor, M., additional, Dror, S., additional, Tsadok, Y., additional, Bachner-Hinenzon, N., additional, Katz, A., additional, Liel-Cohen, N., additional, Etzion, Y., additional, Mlynarski, R., additional, Mlynarska, A., additional, Wilczek, J., additional, Sosnowski, M., additional, Sinha, A. M., additional, Sinha, D., additional, Noelker, G., additional, Brachmann, J., additional, Weidemann, F., additional, Ertl, G., additional, Jones, M., additional, Searle, N., additional, Cocker, M., additional, Ilsley, E., additional, Foley, P., additional, Khiani, R., additional, Nelson, K. E., additional, Turley, A. J., additional, Owens, W. A., additional, James, S. A., additional, Linker, N. J., additional, Velagic, V., additional, Cikes, M., additional, Pezo Nikolic, B., additional, Puljevic, D., additional, Separovic-Hanzevacki, J., additional, Lovric-Bencic, M., additional, Biocina, B., additional, Milicic, D., additional, Kawata, H., additional, Chen, L., additional, Phan, H., additional, Anand, K., additional, Feld, G., additional, Birgesdotter-Green, U., additional, Fernandez Lozano, I., additional, Mitroi, C., additional, Toquero Ramos, J., additional, Castro Urda, V., additional, Monivas Palomero, V., additional, Corona Figueroa, A., additional, Hernandez Reina, L., additional, Alonso Pulpon, L., additional, Gate-Martinet, A., additional, Da Costa, A., additional, Rouffiange, P., additional, Cerisier, A., additional, Bisch, L., additional, Romeyer-Bouchard, C., additional, Isaaz, K., additional, Morales, M.- A., additional, Bianchini, E., additional, Startari, U., additional, Faita, F., additional, Bombardini, T., additional, Gemignani, V., additional, Piacenti, M., additional, Adhya, S., additional, Kamdar, R. H., additional, Millar, L. M., additional, Burchardt, C., additional, Murgatroyd, F. D., additional, Klug, D., additional, Kouakam, C., additional, Guedon-Moreau, L., additional, Marquie, C., additional, Benard, S., additional, Kacet, S., additional, Cortez-Dias, N., additional, Carrilho-Ferreira, P., additional, Silva, D., additional, Goncalves, S., additional, Valente, M., additional, Marques, P., additional, Carpinteiro, L., additional, Sousa, J., additional, Keida, T., additional, Nishikido, T., additional, Fujita, M., additional, Chinen, T., additional, Kikuchi, T., additional, Nakamura, K., additional, Ohira, H., additional, Takami, M., additional, Anjo, D., additional, Meireles, A., additional, Gomes, C., additional, Roque, C., additional, Pinheiro Vieira, A., additional, Lagarto, V., additional, Reis, H., additional, Torres, S., additional, Ortega, D. F., additional, Barja, L. D., additional, Montes, J. P., additional, Logarzo, E., additional, Bonomini, P., additional, Mangani, N., additional, Paladino, C., additional, Chwyczko, T., additional, Smolis-Bak, E., additional, Sterlinski, M., additional, Pytkowski, M., additional, Firek, B., additional, Jankowska, A., additional, Szwed, H., additional, Nakajima, I., additional, Noda, T., additional, Okamura, H., additional, Satomi, K., additional, Aiba, T., additional, Shimizu, W., additional, Aihara, N., additional, Kamakura, S., additional, Brzozowski, W., additional, Tomaszewski, A., additional, Wysokinski, A., additional, Bertoldi, E. G., additional, Rohde, L. E., additional, Zimerman, L. I., additional, Pimentel, M., additional, Polanczyk, C. A., additional, Boriani, G., additional, Lunati, M., additional, Gasparini, M., additional, Landolina, M., additional, Lonardi, G., additional, Pecora, D., additional, Santini, M., additional, Valsecchi, S., additional, Rubinstein, B. J., additional, Wang, D. Y., additional, Cabreriza, S. E., additional, Richmond, M. E., additional, Rusanov, A., additional, Quinn, T. A., additional, Cheng, B., additional, Spotnitz, H. M., additional, Kristiansen, H. M., additional, Vollan, G., additional, Hovstad, T., additional, Keilegavlen, H., additional, Faerestrand, S., additional, Brigesdotter-Green, U., additional, Nawar, A. M. R., additional, Ragab, D. A. L. I. A., additional, Eluhsseiny, R. A. N. I. A., additional, Abdelaziz, A. H. M. E. D., additional, Nof, E., additional, Abu Shama, R., additional, Buber, J., additional, Kuperstein, R., additional, Feinberg, M. S., additional, Barlev, D., additional, Eldar, M., additional, Glikson, M., additional, Badran, H., additional, Samir, R., additional, Tawfik, M., additional, Amin, M., additional, Eldamnhoury, H., additional, Khaled, S., additional, Tolosana, J. M., additional, Martin, A. M., additional, Hernandez-Madrid, A., additional, Macias, A., additional, Fernandez-Lozano, I., additional, Osca, J., additional, Quesada, A., additional, Padeletti, L., additional, Botto, G. L., additional, De Santo, T., additional, Szwed, A., additional, Martinez, J. G., additional, Degand, B., additional, Villani, G. Q., additional, Leclercq, C., additional, Ritter, P., additional, Watanabe, I., additional, Nagashima, K., additional, Okumura, Y., additional, Kofune, M., additional, Ohkubo, K., additional, Nakai, T., additional, Hirayama, A., additional, Mikhaylov, E., additional, Vander, M., additional, Lebedev, D., additional, Zarse, M., additional, Suleimann, H., additional, Bogossian, H., additional, Stegelmeyer, J., additional, Ninios, I., additional, Karosienne, Z., additional, Kloppe, A., additional, Lemke, B., additional, John, S., additional, Gaspar, T., additional, Rolf, S., additional, Sommer, P., additional, Hindricks, G., additional, Piorkowski, C., additional, Fernandez-Armenta, J., additional, Mont, L. L., additional, Zeljko, H., additional, Andreu, D., additional, Herzcku, C., additional, Boussy, T., additional, Brugada, J., additional, Obayahi, T., additional, Hegrenes, J., additional, Lim, E., additional, Mediratta, V., additional, Bautista, R., additional, Teplitsky, L., additional, Van Huls Van Taxis, C. F. B., additional, Wijnmaalen, A. P., additional, Gawrysiak, M., additional, Schuijf, J. D., additional, Bax, J. J., additional, Huo, Y., additional, Richter, S., additional, Arya, A., additional, Bollmann, A., additional, Akca, F., additional, Bauernfeind, T., additional, Schwagten, B., additional, De Groot, N. M. S., additional, Jordaens, L., additional, Szili-Torok, T., additional, Miller, S., additional, Kastner, G., additional, Maury, P., additional, Della Bella, P., additional, Delacretaz, E., additional, Sacher, F., additional, Maccabelli, G., additional, Brenner, R., additional, Rollin, A., additional, Jais, P., additional, Vergara, P., additional, Trevisi, N., additional, Ricco, A., additional, Petracca, F., additional, Bisceglia, C., additional, Baratto, F., additional, Salguero Bodes, R., additional, Fontenla Cerezuela, A., additional, De Riva Silva, M., additional, Lopez Gil, M., additional, Mejia Martinez, E., additional, Jurado Roman, A., additional, Montero Alvarez, M., additional, Arribas Ynsaurriaga, F., additional, Baszko, A., additional, Krzyzanowski, K., additional, Bobkowski, W., additional, Surmacz, R., additional, Zinka, E., additional, Siwinska, A., additional, Szyszka, A., additional, Perez Silva, A., additional, Estrada Mucci, A., additional, Ortega Molina, M., additional, Lopez Sendon, J. 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H., additional, Hero, M., additional, Mizobuchi, M., additional, Enjoji, Y., additional, Yazaki, Y., additional, Shibata, K., additional, Funatsu, A., additional, Kobayashi, T., additional, Nakamura, S., additional, Amit, G., additional, Pertzov, B., additional, Zahger, D., additional, Medesani, L., additional, Rana, R., additional, Albano, F., additional, Fraguas, H., additional, Pedersen, S. S., additional, Hoogwegt, M. T., additional, Theuns, D. A. M. J., additional, Van Den Broek, K. C., additional, Tekle, F. B., additional, Habibovic, M., additional, Alings, M., additional, Van Der Voort, P., additional, Denollet, J., additional, Vrazic, H., additional, Jilek, C., additional, Lesevic, H., additional, Tzeis, S., additional, Semmler, V., additional, Gold, M. R., additional, Burke, M. C., additional, Bardy, G. H., additional, Varma, N., additional, Pavri, B., additional, Stambler, B., additional, Michalski, J., additional, Investigators, T. R. U. S. 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A., additional, Iitsuka, K., additional, Kondo, T., additional, Goebbert, K., additional, Karossiene, Z., additional, Goldman, D., additional, Kallen, B., additional, Kerpi, E., additional, Sardo, J., additional, Arsenos, P., additional, Gatzoulis, K., additional, Manis, G., additional, Dilaveris, P., additional, Tsiachris, D., additional, Mytas, D., additional, Asimakopoulos, S., additional, Stefanadis, C., additional, Sideris, S., additional, Kartsagoulis, E., additional, Barbosa, O., additional, Marocolo Junior, M., additional, Silva Cortes, R., additional, Moraes Brandolis, R. A., additional, Oliveira, L. F., additional, Pertili Rodrigues De Resende, L. A., additional, Vieira Da Silva, M. A., additional, Dias Da Silva, V. J., additional, Hegazy, R. A., additional, Sharaf, I. A., additional, Fadel, F., additional, Bazaraa, H., additional, Esam, R., additional, Deshko, M. S., additional, Snezhitsky, V. A., additional, Stempen, T. P., additional, Kuroki, K., additional, Igawa, M., additional, Kuga, K., additional, Ferreira Santos, L., additional, Dionisio, T., additional, Nunes, L., additional, Machado, J., additional, Castedo, S., additional, Henriques, C., additional, Matos, A., additional, Oliveira Santos, J., additional, Kraaier, K., additional, Olimulder, M. A. G. M., additional, Galjee, M. A., additional, Van Dessel, P. F. H. M., additional, Van Der Palen, J., additional, Wilde, A. A. M., additional, Scholten, M. F., additional, Chouchou, F., additional, Poupard, L., additional, Philippe, C., additional, Court-Fortune, I., additional, Barthelemy, J.- C., additional, Roche, F., additional, Dolgoshey, T. S., additional, Madekina, G. A., additional, Sugiura, S., additional, Fujii, E., additional, Senga, M., additional, Dohi, K., additional, Sugiura, E., additional, Nakamura, M., additional, Ito, M., additional, Eitel, C., additional, Mendell, J., additional, Lasseter, K., additional, Shi, M., additional, Urban, L., additional, Hatala, R., additional, Hlivak, P., additional, De Melis, M., additional, Garutti, C., additional, Corbucci, G., additional, Mlcochova, H., additional, Maxian, R., additional, Arbelo, E., additional, Dogac, A., additional, Luepkes, C., additional, Ploessnig, M., additional, Chronaki, C., additional, Hinterbuchner, L., additional, Guillen, A., additional, Bun, S. S., additional, Latcu, D. G., additional, Franceschi, F., additional, Prevot, S., additional, Koutbi, L., additional, Ricard, P., additional, Saoudi, N., additional, Nazari, N., additional, Alizadeh, A., additional, Sayah, S., additional, Hekmat, M., additional, Assadian, M., additional, Ahmadzadeh, A., additional, Wnuk, M., additional, Jedrzejczyk-Spaho, J., additional, Kruszelnicka, O., additional, Piwowarska, W., additional, Fedorowski, A., additional, Burri, P., additional, Juul-Moller, S., additional, Melander, O., additional, Mitro, P., additional, Murin, P., additional, Kirsch, P., additional, Habalova, V., additional, Slaba, E., additional, Matyasova, E., additional, Barlow, M. A., additional, Blake, R. J., additional, Rostoff, P., additional, Wojewodka Zak, E., additional, Froidevaux, L., additional, Sarasin, F. P., additional, Louis-Simonet, M., additional, Hugli, O., additional, Yersin, B., additional, Schlaepfer, J., additional, Mischler, C., additional, Pruvot, E., additional, Occhetta, E., additional, Frascarelli, F., additional, Burali, A., additional, and Dovellini, E., additional
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Andersson, T., primary, Magnusson, A., additional, Bryngelsson, I.- L., additional, Frobert, O., additional, Henriksson, K. M., additional, Edvardsson, N., additional, Poci, D., additional, Polovina, M., additional, Potpara, T., additional, Licina, M., additional, Mujovic, N., additional, Kocijancic, A., additional, Simic, D., additional, Ostojic, M. C., additional, Providencia, R. A., additional, Botelho, A., additional, Trigo, J., additional, Nascimento, J., additional, Quintal, N., additional, Mota, P., additional, Leitao-Marques, A. M., additional, Bosch, R. F., additional, Kirch, W., additional, Rosin, L., additional, Willich, S. N., additional, Pittrow, D., additional, Bonnemeier, H., additional, Valenza, M. C., additional, Martin, L., additional, Munoz Casaubon, T., additional, Valenza, G., additional, Botella, M., additional, Serrano, M., additional, Valenza, B., additional, Cabrera, I., additional, Anderson, K., additional, Benzaquen, B. S., additional, Koziolova, N., additional, Nikonova, J., additional, Shilova, Y., additional, Scherr, D., additional, Narayan, S., additional, Wright, M., additional, Krummen, D., additional, Jadidi, A., additional, Jais, P., additional, Haissaguerre, M., additional, Hocini, M., additional, Hunter, R., additional, Liu, Y., additional, Lu, Y., additional, Wang, W., additional, Schilling, R. J., additional, Bernstein, S., additional, Wong, B., additional, Rooke, R., additional, Vasquez, C., additional, Shah, R., additional, Rosenberg, S., additional, Chinitz, L., additional, Morley, G., additional, Bashir Choudhary, M., additional, Holmqvist, F., additional, Carlson, J., additional, Nilsson, H.- J., additional, Platonov, P. G., additional, Jadidi, A. S., additional, Cochet, H., additional, Miyazaki, S., additional, Shah, A. J., additional, Marrouche, N., additional, Calvo, N., additional, Nadal, M., additional, Andreu, D., additional, Tamborero, D., additional, Diaz, F. 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F., additional, Ouali, S., additional, Hammemi, R., additional, Hammas, S., additional, Kacem, S., additional, Gribaa, R., additional, Neffeti, E., additional, Remedi, F., additional, Boughzela, E., additional, Korantzopoulos, P., additional, Letsas, K., additional, Christogiannis, Z., additional, Kalantzi, K., additional, Ntorkos, A., additional, Goudevenos, J., additional, Foley, P. W. X., additional, Yung, L., additional, Barnes, E., additional, Kikuchi, M., additional, Ito, H., additional, Miyoshi, F., additional, Pecini, R., additional, Marott, J. M., additional, Jensen, G. B., additional, Theilade, J., additional, Mine, T., additional, Kodani, T., additional, Masuyama, T., additional, Mozos, I. M., additional, Serban, C., additional, Costea, C., additional, Susan, L., additional, Barthel, P., additional, Mueller, A., additional, Malik, M., additional, Schmidt, G., additional, Karakurt, O., additional, Kilic, H., additional, Munevver Sari, D. R., additional, Mroczek-Czernecka, D., additional, Pietrucha, A. Z., additional, Borowiec, A., additional, Wnuk, M., additional, Bzukala, I., additional, Kruszelnicka, O., additional, Konduracka, E., additional, Nessler, J., additional, Kikuchi, Y., additional, Meireles, A., additional, Gomes, C., additional, Anjo, D., additional, Roque, C., additional, Pinheiro Vieira, A., additional, Lagarto, V., additional, Hipolito Reis, A., additional, Torres, S., additional, Miller, L., additional, Vedrenne, G., additional, Bruguiere, E., additional, Redheuil, A., additional, Lavergne, T., additional, Le Heuzey, J. Y., additional, Mousseaux, E., additional, Hersi, A., additional, Alhabib, K., additional, Alfaleh, H., additional, Sulaiman, K., additional, Almahmeed, W., additional, Alsuwidi, J., additional, Amin, H., additional, Almotarreb, A., additional, Pang, H. W. K., additional, Michael, K., additional, Pereira, E. J., additional, Munt, P. W., additional, Fitzpatrick, M. 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M., additional, Daba, L., additional, Liebrecht, K., additional, Piwowarska, W., additional, Toquero Ramos, J., additional, Perez Pereira, E., additional, Mitroi, C., additional, Castro Urda, V., additional, Fernandez Villanueva, J. M., additional, Corona Figueroa, A., additional, Hernandez Reina, L., additional, Fernandez Lozano, I., additional, Bartoletti, A., additional, Bocconcelli, P., additional, Giuli, S., additional, Massa, R., additional, Svetlich, C., additional, Tarsi, G., additional, Tronconi, F., additional, Vitale, E., additional, Stryjewski, P., additional, Wegrzynowska, M., additional, Lousinha, A., additional, Labandeiro, J., additional, Antunes, E., additional, Silva, S., additional, Alves, S., additional, Timoteo, A., additional, Oliveira, M., additional, Cruz Ferreira, R., additional, and Jedrzejczyk-Spaho, J., additional
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Deshmukh, A., primary, Sharma, S. S., additional, Gobal, F. G., additional, Singla, S. S., additional, Hebbar, P. H., additional, Paydak, H. P., additional, Igarashi, M., additional, Tada, H., additional, Sekiguchi, Y., additional, Yamasaki, H., additional, Kuroki, K., additional, Machino, T., additional, Yoshida, K., additional, Aonuma, K., additional, Shavadia, J., additional, Otieno, H., additional, Yonga, G., additional, Jinah, A., additional, Qvist, J. F., additional, Soerensen, P. H., additional, Dixen, U., additional, Ramirez-Marrero, M. A., additional, Perez-Villardon, B., additional, Gaitan-Roman, D., additional, Jimenez-Navarro, M., additional, Delgado-Prieto, J. L., additional, De Teresa-Galvan, E., additional, De Mora-Martin, M., additional, Deshmukh, A., additional, Hebbar, P. B., additional, Wei, W. X., additional, Bardari, S., additional, Zecchin, M., additional, Salame', R., additional, Vitali Serdoz, L., additional, Di Lenarda, A., additional, Guerrini, N., additional, Barbati, G., additional, Sinagra, G., additional, Hanazawa, K., additional, Kaitani, K., additional, Nakagawa, Y., additional, Lenaerts, I., additional, Driesen, R., additional, Hermida, N., additional, Heidbuchel, H., additional, Janssens, S., additional, Balligand, J. L., additional, Sipido, K. R., additional, Willems, R., additional, Sehra, R., additional, Krummen, D., additional, Briggs, C., additional, Narayan, S., additional, Tanaka, Y., additional, Hirao, K., additional, Nakamura, T., additional, Inaba, O., additional, Yagishita, A., additional, Higuchi, K., additional, Hachiya, H., additional, Isobe, M., additional, Kallergis, E., additional, Kanoupakis, E. M., additional, Mavrakis, H. E., additional, Goudis, C. A., additional, Maliaraki, N. E., additional, Vardas, P. 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S., additional, Scherr, D., additional, Derval, N., additional, Hocini, M., additional, Haissaguerre, M., additional, Castrejon Castrejon, S., additional, Largo-Aramburu, C., additional, Sachar, J., additional, Gang, E., additional, Estrada, A., additional, Doiny, D., additional, De Miguel, E., additional, Merino, J. L., additional, Trevisi, N., additional, Ricco, A., additional, Petracca, F., additional, Baratto, F., additional, Bisceglie, A., additional, Maccabelli, G., additional, El-Damaty, A., additional, Sapp, J., additional, Warren, J., additional, Macinnis, P., additional, Horacek, M., additional, Dinov, B., additional, Schoenbauer, R., additional, Braunschweig, F., additional, Arya, A., additional, Andreu, D., additional, Berruezo, A., additional, Ortiz, J. T., additional, Silva, E., additional, De Caralt, T. M., additional, Fernandez-Armenta, J., additional, Perez-Silva, A., additional, Ortega, M., additional, Lopez-Sendon, J. L., additional, Regoli, F., additional, Faletra, F., additional, Nucifora, G., additional, Pasotti, E., additional, Moccetti, T., additional, Klersy, C., additional, Casella, M., additional, Dello Russo, A., additional, Moltrasio, M., additional, Zucchetti, M., additional, Fassini, G., additional, Di Biase, L., additional, Natale, A., additional, Tondo, C., additional, Matsuhashi, N., additional, Weig, H. J., additional, Kerst, G., additional, Weretk, S., additional, Seizer, P., additional, Gawaz, M. P., additional, Schreieck, J., additional, Sarquella-Brugada, G., additional, Prada, F., additional, Salling, C. 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B., additional, Jenni, R., additional, Brugada, P., additional, Bakos, Z., additional, Medvedev M, M. M., additional, Jonas Carlsson, J. C., additional, Fredrik Holmqvist, F. H., additional, Pyotr Platonov, P. P., additional, Nurbaev, T., additional, Pirnazarov, M., additional, Nikishin, A., additional, Aagaard, P., additional, Sahlen, A., additional, Bergfeldt, L., additional, Simeonidou, E., additional, Kastellanos, S., additional, Varounis, C., additional, Michalakeas, C., additional, Koniari, C., additional, Nikolopoulou, A., additional, Anastasiou-Nana, M., additional, Furukawa, Y., additional, Yamada, T., additional, Morita, T., additional, Tanaka, K., additional, Iwasaki, Y., additional, Kawasaki, M., additional, Kuramoto, Y., additional, Fukunami, M., additional, Blanche, C., additional, Tran, N., additional, Rigamonti, F., additional, Zimmermann, M., additional, Okisheva, E., additional, Tsaregorodtsev, D., additional, Sulimov, V., additional, Novikova, D., additional, Popkova, T., additional, Udachkina, E., additional, Korsakova, Y., additional, Volkov, A., additional, Novikov, A., additional, Alexandrova, E., additional, Nasonov, E., additional, Arsenos, P., additional, Gatzoulis, K., additional, Manis, G., additional, Dilaveris, P., additional, Gialernios, T., additional, Kartsagoulis, E., additional, Asimakopoulos, S., additional, Stefanadis, C., additional, Marocolo, M., additional, Barbosa Neto, O., additional, Carvalho, A. 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E., additional, Iacoviello, M., additional, Nacci, F., additional, Luzzi, G., additional, Puzzovivo, A., additional, Memeo, M., additional, Quadrini, F., additional, Favale, S., additional, Trucco, M. E., additional, Arce, M., additional, Palazzolo, J., additional, Uribe, W., additional, Maggi, R., additional, Furukawa, T., additional, Croci, F., additional, Solano, A., additional, Brignole, M., additional, Lebreiro, A., additional, Sousa, A., additional, Correia, A. S., additional, Lourenco, P., additional, Oliveira, S., additional, Paiva, M., additional, Freitas, J., additional, Maciel, M. J., additional, Linker, N., additional, Rieger, G., additional, Garutti, C., additional, Edvardsson, N., additional, Salguero Bodes, R., additional, De Riva Silva, M., additional, Fontenla Cerezuela, A., additional, Lopez Gil, M., additional, Mejia Martinez, E., additional, Jurado Roman, A., additional, Garcia Alvarez, S., additional, Arribas Ynsaurriaga, F., additional, Petix, N. R., additional, Del Rosso, A., additional, Guarnaccia, V., additional, Zipoli, A., additional, Rabajoli, F., additional, Foglia Manzillo, G., additional, Tolardo, C., additional, Checchinato, C., additional, Chiaravallotti, S., additional, Santarone, M., additional, Spinnler, M. T., additional, Podoleanu, C., additional, Frigy, A., additional, Dobreanu, D., additional, Ginghina, C., additional, and Carasca, E., additional
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- 2011
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20. [SVT in the EP lab: electrograms don't always show the reentry circuit].
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Bogossian H, Robl S, Bimpong-Buta NY, and Iliodromitis K
- Abstract
Competing Interests: Einhaltung ethischer Richtlinien. Interessenkonflikt: H. Bogossian, S. Robl, N.-Y. Bimpong-Buta und K. Iliodromitis geben an, dass kein Interessenkonflikt besteht. Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.
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- 2024
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21. [The challenge: specialization meets general medicine].
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Bogossian H and Busch S
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- Germany, Humans, Forecasting, General Practice trends, Specialization trends
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- 2024
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22. Arrhythmias in oncological patients: a compact overview for the clinician.
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Iliodromitis K, Hoiczyk M, Bimpong-Buta NY, Seyfarth M, and Bogossian H
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- Humans, Cardiotoxicity etiology, Cancer Survivors, Risk Factors, Arrhythmias, Cardiac chemically induced, Arrhythmias, Cardiac diagnosis, Antineoplastic Agents adverse effects, Neoplasms drug therapy, Neoplasms complications
- Abstract
Chemotherapy is the cornerstone of antineoplastic treatment in patients with malignancies. The cardiotoxic effect of antineoplastic therapy has been known for many decades. Part of chemotherapy-induced cardiotoxicity is the development of heart rhythm disturbances. This short review aims to provide a compact overview for the clinical cardiologist of the dysrhythmic potential created by antineoplastic agents in cancer survivors., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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23. Prognostic Implications of Coronary Artery Sclerosis in Troponin-Positive Patients with Non-Obstructive Coronary Arteries.
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Kreimer F, Schlettert C, Abumayyaleh M, Akin I, Materzok D, Gotzmann M, Schiedat F, Bogossian H, Hijazi MM, Hamdani N, Mügge A, El-Battrawy I, Hemetsberger R, and Aweimer A
- Abstract
Introduction: Coronary sclerosis is a risk factor for the progression to obstructive coronary artery disease (CAD). However, understanding its impact on the outcomes of patients with myocardial infarction and non-obstructive coronary arteries is limited. This study aimed to explore the prognostic influence of coronary sclerosis on in- and out-of-hospital events in troponin-positive patients with non-obstructive coronary arteries., Methods: This study was a retrospective cohort analysis based on prospectively collected data. A total of 24,775 patients who underwent coronary angiography from 2010 to 2021 in a German university hospital were screened, resulting in a final study cohort of 373 troponin-positive patients with non-obstructive coronary arteries and a follow-up period of 6.2 ± 3.1 years. Coronary sclerosis was defined as coronary plaques without angiographically detectable stenotic lesions of 50% or more in the large epicardial coronary arteries. The primary study endpoint was the occurrence of in-hospital events. Secondary endpoints included events during follow-up., Results: Patients with coronary sclerosis were significantly older (70 ± 12 vs. 58 ± 16 years, p < 0.001), had ST-segment elevation less frequently on electrocardiogram (9.4% vs. 18.7%, p = 0.013), and suffered more often from diabetes mellitus (23.3% vs. 13.1%, p = 0.009), arterial hypertension (79.6% vs. 59.8%, p < 0.001), chronic obstructive pulmonary disease (17.1% vs. 9.4%, p = 0.028), chronic kidney disease (22.2% vs. 8.4%, p < 0.001), atrial fibrillation (19.8% vs. 12.2%, p = 0.045), and valvular diseases than patients without CAD. Patients with coronary sclerosis were more likely to receive medication for primary/secondary prevention on admission and at discharge. The incidence of in- and out-of-hospital events was significantly higher in patients with coronary sclerosis (in-hospital: 42.8% vs. 29.9%, p = 0.010; out-of-hospital: 46.0% vs. 26.1%, p < 0.001). Mortality rates tended to be higher in the coronary sclerosis group (29.4% vs. 20.0%, p = 0.066)., Conclusion: Patients diagnosed with coronary sclerosis presented a higher incidence of comorbidities and increased medication use, and experienced higher rates of both in-hospital and out-of-hospital events, primarily due to the clustering of cardiovascular risk factors., (© 2024. The Author(s).)
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- 2024
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24. Prevention of cerebral thromboembolism by oral anticoagulation with dabigatran after pulmonary vein isolation for atrial fibrillation: the ODIn-AF trial.
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Schrickel JW, Beiert T, Linhart M, Luetkens JA, Schmitz J, Schmid M, Hindricks G, Arentz T, Stellbrink C, Deneke T, Bogossian H, Sause A, Steven D, Gonska BD, Rudic B, Lewalter T, Zabel M, Geisler T, Schumacher B, Jung W, Kleemann T, Luik A, Veltmann C, Coenen M, and Nickenig G
- Subjects
- Humans, Male, Female, Prospective Studies, Middle Aged, Administration, Oral, Aged, Treatment Outcome, Intracranial Embolism prevention & control, Intracranial Embolism etiology, Intracranial Embolism epidemiology, Antithrombins administration & dosage, Antithrombins adverse effects, Incidence, Follow-Up Studies, Time Factors, Anticoagulants administration & dosage, Anticoagulants adverse effects, Atrial Fibrillation complications, Atrial Fibrillation diagnosis, Atrial Fibrillation surgery, Dabigatran administration & dosage, Dabigatran adverse effects, Pulmonary Veins surgery, Catheter Ablation methods, Catheter Ablation adverse effects
- Abstract
Background and Objectives: Long-term oral anticoagulation (OAC) following successful catheter ablation of atrial fibrillation (AF) remains controversial. Prospective data are missing. The ODIn-AF study aimed to evaluate the effect of OAC on the incidence of silent cerebral embolic events and clinically relevant cardioembolic events in patients at intermediate to high risk for embolic events, free from AF after pulmonary vein isolation (PVI)., Methods: This prospective, randomized, multicenter, open-label, blinded endpoint interventional trial enrolled patients who were scheduled for PVI to treat paroxysmal or persistent AF. Six months after PVI, AF-free patients were randomized to receive either continued OAC with dabigatran or no OAC. The primary endpoint was the incidence of new silent micro- and macro-embolic lesions detected on brain MRI at 12 months of follow-up compared to baseline. Safety analysis included bleedings, clinically evident cardioembolic, and serious adverse events (SAE)., Results: Between 2015 and 2021, 200 patients were randomized into 2 study arms (on OAC: n = 99, off OAC: n = 101). There was no significant difference in the occurrence of new cerebral microlesions between the on OAC and off OAC arm [2 (2%) versus 0 (0%); P = 0.1517] after 12 months. MRI showed no new macro-embolic lesion, no clinical apparent strokes were present in both groups. SAE were more frequent in the OAC arm [on OAC n = 34 (31.8%), off OAC n = 18 (19.4%); P = 0.0460]; bleedings did not differ., Conclusion: Discontinuation of OAC after successful PVI was not found to be associated with an elevated risk of cerebral embolic events compared with continued OAC after a follow-up of 12 months., (© 2023. The Author(s).)
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- 2024
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25. Interrogating a biventricular pacemaker: the importance of 12-lead electrocardiogram.
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Iliodromitis K, Lemke B, Robl S, and Bogossian H
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- Humans, Male, Pacemaker, Artificial, Aged, Cardiac Resynchronization Therapy methods, Cardiac Resynchronization Therapy Devices, Electrocardiography
- Published
- 2024
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26. [Electrophysiological study with a dual chamber pacemaker].
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Bogossian H, Bimpong-Buta NY, Robl S, and Iliodromitis K
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- Humans, Cardiac Pacing, Artificial, Pacemaker, Artificial
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- 2024
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27. Cephalic Vein Cutdown Is Superior to Subclavian Puncture as Venous Access for Patients with Cardiac Implantable Devices after Long-Term Follow-Up.
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Knorr D, Bandorski D, Bogossian H, Iliodromitis K, Schiedat F, Karosiene Z, Mijic D, Lemke B, Seyfarth M, Voß S, Knippschild S, Aweimer A, Zarse M, Kloppe A, and Botsios S
- Abstract
Background: Cephalic vein cutdown (CVC) and subclavian vein puncture (SVP) are the most commonly used access sites for transvenous lead placement of cardiac implantable electronic devices (CIEDs). Limited knowledge exists about the long-term patency of the vascular lumen housing the leads., Methods: Among the 2703 patients who underwent CIED procedures between 2005 and 2013, we evaluated the phlebographies of 162 patients scheduled for an elective CIED replacement (median of 6.4 years after the first operation). The phlebographies were divided into four stenosis types: Type I = 0%, Type II = 1-69%, Type III = 70-99%, and Type IV = occlusion. Due to the fact that no standardized stenosis categorization exists, experienced physicians in consensus with the involved team made the applied distribution. The primary endpoint was the occurrence of stenosis Type III or IV in the CVC group and in the SVP group., Results: In total, 162 patients with venography were enrolled in this study. The prevalence of high-degree stenosis was significantly lower in the CVC group (7/89, 7.8%) than in the SVP group (15/73, 20.5%, p = 0.023). In the CVC group, venographies showed a lower median stenosis (33%) than in the SVP group (median 42%)., Conclusions: The present study showed that the long-term patency of the subclavian vein is higher after CVC than after SVP for venous access in patients with CIED.
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- 2024
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28. Evaluation of troponin I serum levels in patients with arrhythmias with and without coronary artery disease.
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Bandorski D, Höltgen R, Wieczorek M, Ghofrani HA, Bogossian H, and Iliodromitis K
- Subjects
- Humans, Troponin I, Arrhythmias, Cardiac, Tachycardia, Coronary Angiography, Coronary Artery Disease complications, Coronary Artery Disease diagnosis
- Abstract
Background: Elevated levels of cardiac enzymes in the blood are an indicator of ongoing cardiac ischemia. Persistent tachycardia may lead to myocardial ischemia due to oxygen supply-demand mismatch., Objectives: We sought to evaluate the probability of underlying coronary artery disease (CAD) in patients with symptomatic supraventricular (SVT) or ventricular tachyarrhythmias (VT) based on cardiac enzyme level fluctuation., Materials and Methods: Troponin I (TNI) levels were measured twice and coronary angiography was also performed in patients without a history of cardiovascular disease and symptomatic SVT or VT., Results: Of the 114 (group A: CAD (n = 40), group B: no CAD (n = 74)) patients eligible for the study, 34 patients in group A and 64 patients in group B had SVT, while 6 patients in group A and 10 patients in group B had VT. All patients with underlying CAD developed a significantly elevated TNI level compared to baseline, irrespective of arrhythmia type (2.02 ± 7.98 ng/ml vs. 5.64 ± 13.38, p = 0.031). In patients without CAD, TNI level was not significantly elevated compared to the baseline level, irrespective of arrhythmia type (0.34 ± 1.38 ng/ml vs. 0.48 ± 1.48 ng/ml, p = 0.158). Most patients with normal TNI levels (46 of 47 patients; 98 %) had SVT. CAD was present in 13 of 47 patients (27 %) with tachycardia, despite normal TNI levels., Conclusions: Elevated TNI levels are not helpful to discriminate between SVT and VT. An increase in TNI level in repeated blood sampling can help identify patients with higher probability of underlying CAD. Patients with VT demonstrated higher increases in TNI levels, compared to patients with SVT., (© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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29. Conduction system pacing: how far are we from the "electrical" bypass?
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Sdogkos E, Iliodromitis K, Xanthopoulos A, Triposkiadis F, Skoularigis J, Bogossian H, and Vogiatzis I
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- Humans, Electrocardiography methods, Heart Conduction System, Heart Ventricles surgery, Treatment Outcome, Bundle of His, Cardiac Pacing, Artificial methods
- Abstract
Conduction system pacing is an alternative practice to conventional right ventricular apical pacing. It is a method that maintains physiologic ventricular activation, based on a correct pathophysiological basis, in which the pacing lead bypasses the lesion of the electrical fibers and the electrical impulse transmits through the intact adjacent conduction system. For this reason, it might be reasonably characterized by the term "electrical bypass" compared to the coronary artery bypass in revascularization therapy. In this review, reference is made to the sequence of events in which conventional right ventricular pacing may cause adverse outcomes. Furthermore, there is a reference to alternative strategies and pacing sites. Interest focuses on the modalities for which there are data from the literature, namely for the right ventricular (RV) septal pacing, the His bundle pacing (HBP), and the left bundle branch pacing (LBBP). A more extensive reference is about the HBP, for which there are the most updated data. We analyze the considerations that limit HBP-wide application in three axes, and we also present the data for the implantation and follow-up of these patients. The indications with their most important studies to date are then described in detail, not only in their undoubtedly positive findings but also in their weak aspects, because of which this pacing mode has not yet received a strong recommendation for implementation. Finally, there is a report on LBBP, focusing mainly on its points of differentiation from HBP., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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30. [Manifest accessory pathway: localization and ablation with open window].
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Bogossian H, Robl S, Iliodromitis K, and Bimpong-Buta NY
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- Humans, Heart Conduction System surgery, Bundle of His surgery, Electrocardiography, Accessory Atrioventricular Bundle diagnosis, Accessory Atrioventricular Bundle surgery, Catheter Ablation, Wolff-Parkinson-White Syndrome surgery
- Published
- 2023
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31. [Stress testing: a relevant examination in rhythmology].
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Bogossian H, Alhanafi D, Kloppe A, Höltgen R, and Mijic D
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- Humans, Exercise Test, Arrhythmias, Cardiac diagnosis, Tachycardia, Electrocardiography, Coronary Artery Disease
- Abstract
In recent years, imaging techniques have improved enormously. This leads to a decrease in stress testing indication for diagnosis and management of coronary artery diseases. However, stress testing remains an indispensable diagnostic tool for assessing patients' physical activity and their circulatory behavior during exercise. Using stress testing helps to assess patients' heart rate behavior or even to detect or trigger cardiac arrhythmias, for example, assessment of chronotropic competency, tachycardia-triggering or detection of a sudden heart rate drop with relevant bradycardia. The present review focuses on the assessment of stress testing in rhythmology. Since abnormal findings, which may indicate the presence of coronary heart disease, may occur during exercise testing, relevant ischemic criteria are also briefly addressed., (© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2023
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32. [Electrical cardioversion in pacemaker patients with atrial fibrillation].
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Bogossian H, Robl S, Bimpong-Buta NY, and Iliodromitis K
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- Humans, Electric Countershock, Atrial Fibrillation therapy, Pacemaker, Artificial
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- 2023
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33. Editorial: Innovative strategies for the management of life threatening ventricular tachyarrhythmias-from substrate analysis to differential therapy.
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Höltgen R, Bogossian H, and Bandorski D
- Abstract
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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- 2023
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34. Electrocardiogram in patients with pulmonary hypertension.
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Ley L, Höltgen R, Bogossian H, Ghofrani HA, and Bandorski D
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- Humans, Electrocardiography, Heart, Cardiomegaly, Arrhythmias, Cardiac, Bundle-Branch Block, Hypertension, Pulmonary diagnosis, Long QT Syndrome
- Abstract
Introduction: Pulmonary hypertension (PH) is a potentially life-threatening cardiovascular disease defined by a mean pulmonary arterial pressure (mPAP) > 20 mmHg. Due to non-specific symptoms, PH is often diagnosed late and at advanced stage. In addition to other diagnostic modalities, the electrocardiogram (ECG) can help in establishing the diagnosis. Knowledge of typical ECG signs could help to detect PH earlier., Methods: A non-systematic literature review on the typical electrocardiographic patterns of PH was performed., Results: Characteristic signs of PH include right axis deviation, SIQIIITIII and SISIISIII patterns, P pulmonale, right bundle branch block, deep R waves in V1 and V2, deep S waves in V5 and V6, and right ventricular hypertrophy (R in V1 + S in V5, V6 > 1,05 mV). Repolarisation abnormalities such as ST segment depressions or T wave inversions in leads II, III, aVF, and V1 to V3 are common as well. Furthermore, a prolonged QT/QTc interval, an increased heart rate, or supraventricular tachyarrhythmias can be observed. Some parameters may even provide information about the patient's prognosis., Conclusion: Not every PH patient shows electrocardiographic PH signs, especially in mild PH. Thus, the ECG is not useful to completely rule out PH, but provides important clues to PH when symptoms are present. The combination of typical ECG signs and the co-occurrence of electrocardiographic signs with clinical symptoms and elevated BNP levels are particularly suspicious. Diagnosing PH earlier could prevent further right heart strain and improve patient prognosis., (Copyright © 2023 Elsevier Inc. All rights reserved.)
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- 2023
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35. [How to manage asymptomatic arrhythmias in the digital era].
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Busch S and Bogossian H
- Subjects
- Humans, Arrhythmias, Cardiac diagnosis, Arrhythmias, Cardiac therapy, Electrocardiography, Ambulatory
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- 2023
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36. Perioperative complications after pacemaker implantation: higher complication rates with subclavian vein puncture than with cephalic vein cutdown.
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Hasan F, Nedios S, Karosiene Z, Scholten M, Lemke B, Tulka S, Knippschild S, Macher-Heidrich S, Adomeit HJ, Zarse M, and Bogossian H
- Subjects
- Humans, Aged, Venous Cutdown methods, Retrospective Studies, Punctures, Subclavian Vein, Pacemaker, Artificial
- Abstract
Purpose: The cephalic vein cutdown (CVC) and the subclavian puncture (SP) is the most common access for pacemaker implantation. The purpose of this study was to compare the peri-/postoperative complications of these approaches., Methods: A retrospective analysis of the quality assurance data of the state of North Rhine-Westphalia was performed to evaluate the peri-/postoperative complications of first pacemaker implantation according to the venous access. The primary endpoint was defined as the occurrence of one of the following: asystole, ventricular fibrillation, pneumothorax, hemothorax, pericardial effusion, pocket hematoma, lead dislocation, lead dysfunction, postoperative wound infection or other complication requiring intervention. Descriptive analysis was done via absolute, relative frequencies and Odds Ratio. Fisher's exact test was used for comparison of the both study groups., Results: From 139,176 pacemaker implantations from 2010 to 2014, 15,483 cases were excluded due to other/double access. The median age was 78 years and the access used was CVC for 75,251 cases (60.8%) and SP for 48,442 cases (39.2%). The implanted devices were mainly dual-chamber pacemakers (73.9% in the CVC group and 78.4% in the SP group), followed by single-chamber pacemakers VVI (24.9% and 19.9% in the CVC and SP group respectively). There were significantly fewer peri/postoperative complications in the CVC group compared to the SP group (2.49% vs. 3.64%, p = 0.0001, OR 1.47; 95% CI 1.38-1.57)., Conclusions: CVC as venous access for pacemaker implantation has significantly fewer peri/postoperative complications than SP and appears to be an advantageous technique., (© 2022. The Author(s).)
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- 2023
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37. [Asymptomatic bradycardia and pacemaker : To implant, or not to implant?]
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Bogossian H, Steinfurt J, Robl S, Bimpong-Buta NY, Iliodromitis K, and Lemke B
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- Humans, Bradycardia diagnosis, Bradycardia etiology, Bradycardia therapy, Treatment Outcome, Retrospective Studies, Defibrillators, Implantable, Pacemaker, Artificial adverse effects, Heart Diseases
- Abstract
The cardiac implantable electronic device (CIED) is the therapy of choice for management of symptomatic bradyarrhythmias. However, the indication for CIED implantation in the cases of asymptomatic bradycardias should be carefully individualized. Incidental electrocardiographic findings in asymptomatic patients (e.g., low baseline heart rates, higher than first-degree atrioventricular block or longer pauses) may complicate the physician's decision regarding the necessity of CIED implantation. The main reason is the inherit risk of short- and long-term complications with every CIED implantation, i.e., peri-operative complications, risk of CIED infection, lead fractures, and the necessity for lead extraction. Therefore, before opting for, or against, CIED implantation, several factors should be considered in the subset of asymptomatic patients., (© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2023
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38. [Initiation and maintenance of atrial fibrillation].
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Bogossian H, Robl S, Bimpong-Buta NY, and Iliodromitis K
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- Humans, Atrial Fibrillation diagnosis, Atrial Fibrillation therapy, Catheter Ablation
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- 2023
- Full Text
- View/download PDF
39. Assessing physical activity with the wearable cardioverter defibrillator in patients with newly diagnosed heart failure.
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Iliodromitis K, Balogh Z, Triposkiadis F, Deftereos S, Vrachatis D, Bimpong-Buta NY, Schiedat F, and Bogossian H
- Abstract
Background: The wearable cardioverter defibrillator (WCD), (LifeVest, ZOLL, Pittsburgh, PA, USA) is a medical device designed for the temporary detection and treatment of malignant ventricular tachyarrhythmias. WCD telemonitoring features enable the evaluation of the physical activity (PhA) of the patients. We sought to assess with the WCD the PhA of patients with newly diagnosed heart failure., Methods: We collected and analyzed the data of all patients treated with the WCD in our clinic. Patients with newly diagnosed ischemic, or non-ischemic cardiomyopathy and severely reduced ejection fraction, who were treated with the WCD for at least 28 consecutive days and had a compliance of at least 18 h the day were included., Results: Seventy-seven patients were eligible for analysis. Thirty-seven patients suffered from ischemic and 40 from non-ischemic heart disease. The average days the WCD was carried was 77.3 ± 44.6 days and the mean wearing time was 22.8 ± 2.1 h. The patients showed significantly increased PhA measured by daily steps between the first two and the last two weeks (Mean steps in the first 2 weeks: 4,952.6 ± 3,052.7 vs. mean steps in the last 2 weeks: 6,119.6 ± 3,776.2, p -value: < 0.001). In the end of the surveillance period an increase of the ejection fraction was observed (LVEF-before: 25.8 ± 6.6% vs. LVEF-after: 37.5 ± 10.6%, p < 0.001). Improvement of the EF did not correlate with the improvement of PhA., Conclusion: The WCD provides useful information regarding patient PhA and may be additionally utilized for early heart failure treatment adjustment., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor DD declared a past co-authorship with the author HB., (© 2023 Iliodromitis, Balogh, Triposkiadis, Deftereos, Vrachatis, Bimpong-Buta, Schiedat and Bogossian.)
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- 2023
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40. Analysis of the effect of cortisone on the QT interval.
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Bandorski D, Bogossian H, Ghofrani HA, Zarse M, Allendörfer J, and Höltgen R
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- Humans, Adult, Middle Aged, Electrocardiography, Pilot Projects, Arrhythmias, Cardiac chemically induced, Arrhythmias, Cardiac drug therapy, Heart Rate, Cortisone, Long QT Syndrome chemically induced, Long QT Syndrome diagnosis, Long QT Syndrome drug therapy
- Abstract
Background: Cardiac death caused by malignant arrhythmias is very prevalent. Prolongation of the QT interval is a relevant aspect in arrhythmia mechanisms. Prior studies have revealed that the QTc interval could be shortened by cortisone. Moreover, in an animal model of long QT syndrome, cortisone treatment shortens the ventricular action potential duration. The present study investigated the effect of methylprednisolone (MPS) on the QTc interval in cardiovascularly healthy humans., Methods: Patients who had just been diagnosed with multiple sclerosis receiving MPS therapy were analysed prospectively. Demographic data, laboratory values, anti-arrhythmic medication and baseline and follow-up ECGs were extracted from the patients' medical records., Results: Seventy-eight patients were included. The mean ± standard deviation age was 47 ± 15 years. The values of the electrolytes were normal. All patients were treated with MPS for 3 or 5 days. The heart rate increased at the beginning of MPS therapy and decreased during the subsequent period. ECG measurements showed that the QTc interval was prolonged at the beginning of MPS therapy and shortened over the course of treatment. The longest QTc intervals were obtained by calculation with Bazett's formula., Conclusions: In humans, cortisone shortens the QTc interval over time. The analysis indicates a cumulative effect of cortisone that lasts longer. The results of our pilot study reveal that cortisone might be added to therapeutic strategies in patients with long QT syndromes. Further clinical studies have to be carried out to analyze potential clinical options., (Copyright © 2023 Elsevier Inc. All rights reserved.)
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- 2023
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41. Incidence and prognostic significance of malignant arrhythmias during (repetitive) Holter electrocardiograms in patients with pulmonary hypertension.
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Bandorski D, Heibel S, Höltgen R, Bogossian H, Ghofrani HA, Zarse M, and Gall H
- Abstract
Background: In patients with pulmonary hypertension (PH), increased pulmonary vascular resistance (PVR) may lead to increased right ventricular afterload and cardiac remodelling, potentially providing the substrate for ventricular arrhythmias. Studies dealing with long term monitoring of patients with PH are rare. The present study evaluated the incidence and the types of arrhythmias retrospectively recorded by Holter ECG in patients with newly detected PH during a long-term Holter ECG follow-up. Moreover, their impact on patient survival was evaluated., Patients and Methods: Medical records were screened for demographic data, aetiology of PH, incidence of coronary heart disease, level of brain natriuretic peptide (BNP), results from Holter ECG monitoring, 6-minute walk test distance, echocardiographic data and hemodynamic data derived from right heart catheterization. Two subgroups were analyzed: 1. patients ( n = 65) with PH (group 1 + 4) and derivation of at least 1 Holter ECG within 12 months from initial detection of PH and 2. patients (all PH etiologies, n = 59) with 3 follow-up Holter ECGs. The frequency and complexity of premature ventricular contractions (PVC) was classified into "lower" and "higher" (=non sustained ventricular tachycardia, nsVT) burden., Results: Holter ECG revealed sinus rhythm (SR) in most of the patients ( n = 60). Incidence of atrial fibrillation (AFib) was low ( n = 4). Patients with premature atrial contractions (PAC) tend to have a shorter period of survival ( p = 0.098), PVC were not correlated with significant survival differences. During follow-up PAC and PVC were common in all PH groups. Holter ECG revealed non sustained ventricular tachycardia in 19/59 patients [(32.2%); n = 6 during first Holter-ECG, n = 13 during second/third Holter-ECG]. In all patients suffering from nsVT during follow-up previous Holter ECG revealed multiform/repetitive PVC. PVC burden was not linked to differences in systolic pulmonary arterial pressure, right atrial pressure, brain natriuretic peptide and results of six-minute walk test., Conclusion: Patients with PAC tend to have a shortened survival. None of the evaluated parameters (BNP, TAPSE, sPAP) was correlated with the development of arrhythmias. Patients with multiform/repetitive PVC seem to be at risk for ventricular arrhythmias., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2023 Bandorski, Heibel, Höltgen, Bogossian, Ghofrani, Zarse and Gall.)
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- 2023
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42. Efficacy, Safety and Feasibility of Superior Vena Cava Isolation in Patients Undergoing Atrial Fibrillation Catheter Ablation: An Up-to-Date Review.
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Vrachatis DA, Papathanasiou KA, Kossyvakis C, Giotaki SG, Deftereos G, Kousta MS, Iliodromitis KE, Bogossian H, Avramides D, Giannopoulos G, Lambadiari V, Siasos G, Papaioannou TG, and Deftereos S
- Abstract
Pulmonary vein isolation (PVI) is the cornerstone in atrial fibrillation (AF) ablation; yet, the role of arrhythmogenic superior vena cava (SVC) is increasingly recognized and different ablation strategies have been employed in this context. SVC can act as a trigger or perpetuator of AF, and its significance might be more pronounced in patients undergoing repeated ablation. Several cohorts have examined efficacy, safety and feasibility of SVC isolation (SVCI) among AF patients. The majority of these studies explored as-needed SVCI during index PVI, and only a minority of them included repeated ablation subjects and non-radiofrequency energy sources. Studies of heterogeneous design and intent have explored both empiric and as-needed SVCI on top of PVI and reported inconclusive results. These studies have largely failed to demonstrate any clinical benefit in terms of arrhythmia recurrence, although safety and feasibility are undisputable. Mixed population demographics, small number of enrollees and short follow-up are the main limitations. Procedural and safety data are comparable between empiric SVCI and as-needed SVCI, and some studies suggested that empiric SVCI might be associated with reduced AF recurrences in paroxysmal AF patients. Currently, no study has compared different ablation energy sources in the setting of SVCI, and no randomized study has addressed as-needed SVCI on top of PVI. Furthermore, data regarding cryoablation are still in their infancy, and regarding SVCI in patients with cardiac devices more safety and feasibility data are needed. PVI non-responders, patients undergoing repeated ablation and patients with long SVC sleeves could be potential candidates for SVCI, especially via an empiric approach. Although many technical aspects remain unsettled, the major question to answer is which clinical phenotype of AF patients might benefit from SVCI?
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- 2023
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43. [Ventricular tachyarrhythmic event: One-lead ECG diagnosis].
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Iliodromitis K, Robl S, Bimpong-Buta NY, and Bogossian H
- Subjects
- Humans, Electrocardiography, Tachycardia, Ventricular diagnosis
- Published
- 2023
- Full Text
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44. Cardiac Resynchronization Therapy: Current Guidelines and Recent Advances Beyond Drug Treatment.
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Butter C, Seifert M, Georgi C, Iliodromitis K, and Bogossian H
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- Humans, Stroke Volume, Ventricular Function, Left, Bundle-Branch Block therapy, Heart Ventricles, Treatment Outcome, Cardiac Resynchronization Therapy methods, Heart Failure therapy
- Abstract
Cardiac resynchronization therapy (CRT) is the therapy of choice for patients with symptomatic systolic heart failure (HF) and left bundle branch block (LBBB), despite optimal medical therapy (OMT). The recently published 2021 European Society of Cardiology (ESC) Guidelines on cardiac pacing and cardiac resynchronization therapy highlight the importance of CRT on top of OMT in HF patients with left ventricular ejection fraction (LVEF) ≤ 35%, sinus rhythm and typical LBBB with QRS duration ≥ 150 ms. In the presence of medically intractable or recurrent after catheter ablation atrial fibrillation (AF), AV nodal ablation as an adjuvant therapy becomes more relevant in patients qualifying for the implantation of a biventricular system. Furthermore, CRT may be considered in cases when increased pacing of the right ventricle is not desirable. However, alternative pacing sites and strategies are currently available, if the CRT is not feasible and effective in patients. However, strategies targeting "multi-sides" or using "multi-leads" have shown superiority over classic CRT. On the other hand, conduction system pacing seems to be a promising technique. Although early results are positive, consistency during the long term is pending. The indication for additional defibrillation therapy (ICD) may occasionally be unnecessary and has to be considered individually. Due to the great development and success of heart failure drug therapy, its positive effect on LV function can lead to enormous improvement. Physicians must await these effects and findings, which hopefully could lead to a relevant LV improvement resulting in a definitive decision against an ICD., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
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- 2023
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45. [Fast and irregular wide-complex tachycardia].
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Bogossian H, Iliodromitis K, Tsianakas N, and Bimpong-Buta NY
- Subjects
- Humans, Tachycardia diagnosis, Electrocardiography
- Published
- 2022
- Full Text
- View/download PDF
46. [Effects of electrical cardioversion on pulmonary veins].
- Author
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Bogossian H, Tsianakas N, Bandorski D, and Iliodromitis K
- Subjects
- Electric Countershock, Humans, Atrial Fibrillation therapy, Pulmonary Veins surgery
- Published
- 2022
- Full Text
- View/download PDF
47. Long-term prognosis of successful left ventricular substrate modification of electrical storm.
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Margkarian A, Bogossian H, Bandorski D, Khan A, Hasan F, Fortmann T, Jahaj K, Lemke B, and Zarse M
- Abstract
Introduction: The Electrical storm (ES) subsumes a state of electrical instability of the heart, which manifests itself in repeated and potentially fatal ventricular arrhythmias (VA). We examine the long-term effects of substrate modification with regards to mortality, ventricular tachycardia (VT) recurrences and hospitalization depending on age, gender, heart function, scare location, VT documentation, postprocedural electrical stimulation (PES) and induced VTs., Methods: From 08/2008 and 09/2019 160 consecutive patients admitted for ES ablation via electroanatomical mapping were followed up until 04/2021., Results: 50/160 patients showed VT recurrences after 13.8 ± 21.7 (0.0-80.3) months, with a characteristic steep curve directly after ES and then a rapid decline leading to a plateau (first month 10/50 (20%), first year 35/50 VT recurrences (70%) Mortality rates followed a similar pattern also the initial decline was not as steep. 42 patients died during the observation period (26%) after 16.6 ± 16.1 (0.0-67.9) months after ablation day (first month ( n = 7, 16.7%) first year ( n = 21, 50%). Gender, age, scare localization, missing VT documentation did not worsen outcome. Induction of >3 VTs and lack of PES due to hemodynamic instability significantly decreased effectiveness. Finding the entry significantly increased long-term effects., Conclusion: Ablation of ES is safe and feasible independent of a variety of factors. Employing more sophisticated tools to understand the reentry mechanism will further improve the long-term outcome., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Margkarian, Bogossian, Bandorski, Khan, Hasan, Fortmann, Jahaj, Lemke and Zarse.)
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- 2022
- Full Text
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48. Erratum to: Big Data in electrophysiology.
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Nedios S, Iliodromitis K, Kowalewski C, Bollmann A, Hindricks G, Dagres N, and Bogossian H
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- 2022
- Full Text
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49. [Electrophysiologic study to define the underlying heart rhythm].
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Robl S, Bimpong-Buta NY, Iliodromitis K, and Bogossian H
- Subjects
- Electrocardiography, Humans, Electrophysiologic Techniques, Cardiac, Heart Conduction System
- Published
- 2022
- Full Text
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50. Catheter ablation of short-coupled variant of torsade de pointes.
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Steinfurt J, Nazer B, Aguilar M, Moss J, Higuchi S, Zarse M, Trolese L, Gressler A, Faber TS, Odening KE, Zehender M, Bode C, Scheinman MM, Tedrow UB, and Bogossian H
- Subjects
- Humans, DNA-Binding Proteins, Electrocardiography, Retrospective Studies, Ventricular Fibrillation, Catheter Ablation methods, Torsades de Pointes diagnosis, Torsades de Pointes etiology, Ventricular Premature Complexes diagnosis, Ventricular Premature Complexes surgery
- Abstract
Background: The short-coupled variant of torsade de pointes (sc-TdP) is a malignant arrhythmia that frequently presents with ventricular fibrillation (VF) electrical storm. Verapamil is considered the first-line therapy of sc-TdP while catheter ablation is not widely adopted. The aim of this study was to determine the origin of sc-TdP and to assess the outcome of catheter ablation using 3D-mapping., Methods and Results: We retrospectively analyzed five patients with sc-TdP who underwent 3D-mapping and ablation of sc-TdP at five different institutions. Four patients initially presented with sudden cardiac arrest, one patient experienced recurrent syncope as the first manifestation. All patients demonstrated a monomorphic premature ventricular contraction (PVC) with late transition left bundle branch block pattern, superior axis, and a coupling interval of less than 300 ms. triggering recurrent TdP and VF. In four patients, the culprit PVC was mapped to the free wall insertion of the moderator band (MB) with a preceding Purkinje potential in two patients. Catheter ablation using 3D-mapping and intracardiac echocardiography eliminated sc-TdP in all patients, with no recurrence at mean 2.7 years (range 6 months to 8 years) of follow-up., Conclusion: 3D-mapping and intracardiac echocardiography demonstrate that sc-TdP predominantly originates from the MB free wall insertion and its Purkinje network. Catheter ablation of the culprit PVC at the MB free wall junction leads to excellent short- and long-term results and should be considered as first-line therapy in recurrent sc-TdP or electrical storm., (© 2021. The Author(s).)
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- 2022
- Full Text
- View/download PDF
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