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5. Interpreting HIV seroprevalence data from pregnant women

Author

Boisson, Eldonna, Nicoll, Angus, Zaba, Basia, and Rodrigues, Laura C.

Subjects
HIV infection -- Demographic aspects, Pregnant women -- Testing, Prevalence studies (Epidemiology) -- Models, Health
Abstract

Researchers are working on a mathematical model that will allow them to predict the prevalence of HIV infection in women by analyzing the prevalence in pregnant women. Pregnant women are often used in surveys of HIV infection because they receive regular check-ups. However, the prevalence of HIV infection in women may not be the same as in pregnant women because each group has different risk factors and social behaviors. The model can take these differences into account.

Published
1996

9. Human papillomavirus genotypes and their prevalence in a cohort of women in Trinidad.

Author

Andall-Brereton, Glennis M., Hosein, Felicia, Salas, Rosa A., Mohammed, Wayne, Monteil, Michele A., Goleski, Vanessa, Severini, Alberto, Quesnel, Sarah M. M., Carrington, Christine V. F., Boodram, Laura Lee, Boisson, Eldonna, Akpaka, Patrick E., and Paul, Rosemarie C.

Subjects
*PAPILLOMAVIRUSES, *COHORT analysis, *DISEASES in women, *PAPILLOMAVIRUS diseases, *DISEASE prevalence, *CANCER prevention, *CERVICAL cancer, CERVIX uteri tumors
Published
2011

10. Human papillomavirus genotypes and their prevalence in a cohort of women in Trinidad.

Author

Andall-Brereton GM, Hosein F, Salas RA, Mohammed W, Monteil MA, Goleski V, Severini A, Quesnel SM, Carrington CV, Boodram LL, Boisson E, Akpaka PE, and Paul RC

Subjects
Adolescent, Adult, Aged, Female, Genotype, Humans, Middle Aged, Prevalence, Risk Factors, Trinidad and Tobago epidemiology, Young Adult, Papillomaviridae genetics, Papillomavirus Infections epidemiology, Papillomavirus Infections virology
Abstract

Objective: Human papillomavirus (HPV) genotypes and their relative prevalences were determined in a cohort of 310 sexually active women in Trinidad, West Indies., Methods: Cervical samples were collected with Ayre's spatulas and endocervical brushes. Samples were used for the conventional Papanicolaou test and for determining HPV genotypes by amplification of a section of the viral L1 gene, followed by DNA sequencing and probe hybridization., Results: HPV infections were identified in 126 of 310 (40.6%) women. Of them, 83 (65.8%) were infected with high-risk HPV, 16 (12.7%) with low-risk HPV, and 27 (21.4%) with HPV types of unknown risk. HPV 52 (12.7%) was the most frequently occurring high-risk type, followed by HPV 66 (10.3%), HPV 16 (9.5%), and HPV 18 (8.6%). High-risk types HPV 16 and HPV 66 were each found in 3 (20.0%) and HPV 18 was found in 1 (6.6%) of the 15 women with abnormal cytology., Conclusions: Cervical HPV prevalence and heterogeneity of HPV genotypes are high in this Trinidad cohort. The relative importance of HPV genotypes in the development of cervical lesions needs further investigation in Trinidad in order to better understand the epidemiology of HPV infections as well as to determine the role of HPV testing in the screening, prevention, and control of cervical cancer. This pilot study provided important information on the prevalence of HPV genotypes, which will be used in future nationwide studies.

Published
2011

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