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428 results on '"Bommelaer G"'

2. Long-term outcome of patients with steroid-refractory acute severe UC treated with ciclosporin or infliximab

Author

Laharie, D, Bourreille, A, Branche, J, Allez, M, Bouhnik, Y, Filippi, J, Zerbib, F, Savoye, G, Vuitton, L, Moreau, J, Amiot, A, Cosnes, J, Ricart, E, Dewit, O, Lopez-Sanroman, A, Fumery, M, Carbonnel, F, Bommelaer, G, Coffin, B, Roblin, X, van Assche, G, Esteve, M, Farkkila, M, Gisbert, JP, Marteau, P, Nahon, S, de Vos, M, Lambert, J, Mary, JY, and Louis, E

Published
2018
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17. Early Transmural Response Assessed Using Magnetic Resonance Imaging Could Predict Sustained Clinical Remission and Prevent Bowel Damage in Patients with Crohn’s Disease Treated with Anti-Tumour Necrosis Factor Therapy

Author

Messadeg, L, primary, Hordonneau, C, additional, Bouguen, G, additional, Goutorbe, F, additional, Reimund, J M, additional, Goutte, M, additional, Boucher, A L, additional, Scanzi, J, additional, Reymond, M, additional, Allimant, C, additional, Dapoigny, M, additional, Pereira, B, additional, Bommelaer, G, additional, and Buisson, A, additional

Published
2020
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25. Leucine kinetics are different during feeding with whole protein or oligopeptides

Author

Collin-Vidal, C., Cayol, M., Obled, C., Ziegler, F., Bommelaer, G., and Beaufrere B.

Subjects
Artificial feeding -- Physiological aspects, Leucine -- Research, Protein metabolism -- Research, Biological sciences
Abstract

A study of healthy human volunteers during feeding by nasogastric infusion, a protein or a peptide-bases diet shows that the molecular form of nitrogen intake alters the response of leucine kinetics to feeding. Oxidation and protein synthesis are enhanced upon nitrogen administration and with oligopeptides which minimally inhibit protein breakdown. The oligopeptide lowers leucine balance, increasing leucine concentration and nonoxidative disposal.

Published
1994

28. Efficacy of infliximab after failure of subcutaneous anti-TNF agents in patients with ulcerative colitis: A multicentre study

Author

Streichenberger, A., Benjamin Pariente, Bozon, A., Arab, N., Amiot, A., Vuitton, L., Tilmant, M., Nachury, M., Altwegg, R., Delasalle, T., Gagniere, C., Gregoire, B., Fumery, M., Wils, P., Chambrun, G. P., Hebuterne, X., Pereira, B., Bommelaer, G., Buisson, A., Département Gastroentérologie, CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP), Université de Poitiers-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Universitaire de Montpellier (CHU Montpellier ), Département de Gastroentérologie, Hôpital de l'Archet 2, CHU Henri Mondor, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), CHU Amiens-Picardie, Unité de Biostatistique, CRLCC René Gauducheau, Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de la Recherche Agronomique (INRA), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), CHU Henri Mondor [Créteil], and Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)

Subjects
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

34. C01/042 IS INTERFERON ALPHA ATHEROGENIC?

Author

Kuder, P., Abergel, A., Jouanel, P., Bonny, C., Boulant, J., Henquell, C., Brun, H., Lafeuille, H., Dapoigny, M., and Bommelaer, G.

Published
1996

36. The variation of faecal calprotectin after 3 months of anti-TNF therapy is a predictor of sustained clinical remission in patients with Crohn's disease

Author

Sollelis, E., Quinard, R. Minet, Bouguen, G., Goutte, Marion, Goutorbe, F., Bouvier, D., Pereira, B., Bommelaer, G., Buisson, A., CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand, Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), CHU Gabriel Montpied [Clermont-Ferrand], CHU Pontchaillou [Rennes], Centre Hospitalier de la Côte Basque, Unité de Biostatistique, CRLCC René Gauducheau, and Centre Hospitalier de la Côte Basque (CHCB)

Subjects
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

37. Faecal calprotectin as surrogate marker of transmural healing assessed using MRI in patients with Crohn's disease

Author

Allimant, C., Messadeg, L., Quinard, R. Minet, Goutte, Marion, Bouvier, D., Goutorbe, F., Pereira, B., Bommelaer, G., Hordonneau, C., Buisson, A., Département Gastroentérologie, CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Département de Radiologie (LYON - Radio), CHU Lyon, Laboratoire de Biochimie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Centre Hospitalier de la Côte Basque (CHCB), Unité de Biostatistique, CRLCC René Gauducheau, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), and Centre Hospitalier de la Côte Basque

Subjects
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

38. Comparison between faecal chitinase 3-like 1, matrix metalloprotease 9, and calprotectin to assess mucosal healing in Crohn's disease: a multicentre prospective study

Author

Buisson, A., Fumery, M., Hebuterne, X., Benjamin Pariente, Nancey, S., Quinard, R. M., Peyrin-Biroulet, L., Seksik, P., Allez, M., Lambert, C., Dupas, J. L., Filippi, J., Nachury, M., Boschetti, G., Goutte, M., Pereira, B., Bouvier, D., Bommelaer, G., Barnich, N., Vazeille, E., Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de la Recherche Agronomique (INRA), CHU Amiens-Picardie, Département de Gastroentérologie, Hôpital de l'Archet 2, Institut de Chimie des Milieux et Matériaux de Poitiers (IC2MP), Université de Poitiers-Institut national des sciences de l'Univers (INSU - CNRS)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Hospices Civils de Lyon (HCL), Laboratoire de Biochimie, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Hopital Saint-Louis [AP-HP] (AP-HP), Unité de Biostatistique, CRLCC René Gauducheau, Département Gastroentérologie, CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, and Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)

Subjects
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

39. MRI remission after therapeutic intervention is associated with more time spent in clinical corticosteroids-free remission and decreased risk of surgery in Crohn's disease

Author

Buisson, A., Hordonneau, C., Goutorbe, F., Allimant, C., Goutte, Marion, Reymond, M., Pereira, B., Bommelaer, G., Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Département Gastroentérologie, CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Département de Radiologie (LYON - Radio), CHU Lyon, Centre Hospitalier de la Côte Basque (CHCB), Délégation à la Recherche Clinique et à l'Innovation (DRCI), and Centre Hospitalier de la Côte Basque

Subjects
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2017

40. Macrophages from Crohn's disease patients showed a defect to control adherent-invasive Escherichia coli replication influenced by genetic host factors

Author

Buisson, A., Vazeille, Emilie, Ouchchane, L., Goutte, Marion, Hugot, J. -P., Dubois, André, Quinard, R. Minet, Bouvier, D., Bommelaer, G., Barnich, Nicolas, Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne), Département Gastroentérologie, CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Unité de biostatistique, CRLC Val d'Aurelle, Université Paris Diderot - Paris 7 (UPD7), Hôpital Ambroise Paré [AP-HP], CHU Gabriel Montpied [Clermont-Ferrand], and CHU Clermont-Ferrand

Subjects
[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2017

42. P167 The variation of faecal calprotectin level within the first months after bowel resection is predictive of endoscopic postoperative recurrence in patients with Crohn’s disease

Author

Boube, M, primary, Laharie, D, additional, Nancey, S, additional, Hébuterne, X, additional, Fumery, M, additional, Pariente, B, additional, Roblin, X, additional, Peyrin-Biroulet, L, additional, Reymond, M, additional, Allimant, C, additional, Minet-Quinard, R, additional, Pereira, B, additional, Bommelaer, G, additional, and Buisson, A, additional

Published
2019
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43. DOP80 Oral curcumin is not more effective than placebo to prevent endoscopic postoperative recurrence in patients with Crohn's disease treated with concomitant thiopurines: the POPCUR trial

Author

Buisson, A, primary, Laharie, D, additional, Nancey, S, additional, Hébuterne, X, additional, Roblin, X, additional, Nachury, M, additional, Peyrin-Biroulet, L, additional, Fumery, M, additional, Goutorbe, F, additional, Coban, D, additional, Allimant, C, additional, Reymond, M, additional, Vazeille, E, additional, Pereira, B, additional, Goutte, M, additional, and Bommelaer, G, additional

Published
2019
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44. Long-term outcome of patients with steroid-refractory acute severe UC treated with ciclosporin or infliximab.

Author

UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie, Laharie, D, Bourreille, A, Branche, J, Allez, M, Bouhnik, Y, Filippi, J, Zerbib, F, Savoye, G, Vuitton, L, Moreau, J, Amiot, A, Cosnes, J, Ricart, E, Dewit, Olivier, Lopez-Sanroman, A, Fumery, M, Carbonnel, F, Bommelaer, G, Coffin, B, Roblin, X, van Assche, G, Esteve, M, Farkkila, M, Gisbert, J P, Marteau, P, Nahon, S, de Vos, M, Lambert, J, Mary, J Y, Louis, E, Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - (SLuc) Service de gastro-entérologie, Laharie, D, Bourreille, A, Branche, J, Allez, M, Bouhnik, Y, Filippi, J, Zerbib, F, Savoye, G, Vuitton, L, Moreau, J, Amiot, A, Cosnes, J, Ricart, E, Dewit, Olivier, Lopez-Sanroman, A, Fumery, M, Carbonnel, F, Bommelaer, G, Coffin, B, Roblin, X, van Assche, G, Esteve, M, Farkkila, M, Gisbert, J P, Marteau, P, Nahon, S, de Vos, M, Lambert, J, Mary, J Y, Louis, E, and Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives

Abstract

OBJECTIVE: Ciclosporin and infliximab have demonstrated short-term similar efficacy as second-line therapies in patients with acute severe UC (ASUC) refractory to intravenous steroids. The aim of this study was to assess long-term outcome of patients included in a randomised trial comparing ciclosporin and infliximab. DESIGN: Between 2007 and 2010, 115 patients with steroid-refractory ASUC were randomised in 29 European centres to receive ciclosporin or infliximab in association with azathioprine. Patients were followed until death or last news up to January 2015. Colectomy-free survival rates at 1 and 5 years and changes in therapy were estimated through Kaplan-Meier method and compared between initial treatment groups through log-rank test. RESULTS: After a median follow-up of 5.4 years, colectomy-free survival rates (95% CI) at 1 and 5 years were, respectively, 70.9% (59.2% to 82.6%) and 61.5% (48.7% to 74.2%) in patients who received ciclosporin and 69.1% (56.9% to 81.3%) and 65.1% (52.4% to 77.8%) in those who received infliximab (p=0.97). Cumulative incidence of first infliximab use at 1 and 5 years in patients initially treated with ciclosporin was, respectively, 45.7% (32.6% to 57.9%) and 57.1% (43.0% to 69.0%). Only four patients from the infliximab group were subsequently switched to ciclosporin. Three patients died during the follow-up, none directly related to UC or its treatment. CONCLUSIONS: In this cohort of patients with steroid-refractory ASUC initially treated by ciclosporin or infliximab, long-term colectomy-free survival was independent from initial treatment. These long-term results further confirm a similar efficacy and good safety profiles of both drugs and do not favour one drug over the other. TRIAL REGISTRATION NUMBER: EudraCT: 2006-005299-42; ClinicalTrials.gouv number: NCT00542152; post-results.

Published
2018

45. Methotrexate for Corticosteroid- Dependent Ulcerative Colitis: Results of a Placebo Randomized Controlled Trial

Author

Carbonnel F, Colombel JF, Filippi J, Katsanos K, Peyrin-Biroulet L, Allez M, Nachury M, Novacek G, Danese S, Abitbol V, Bossa F, Moreau J, Bommelaer G, Bourreille A, Dupas JL, Roblin X, Bouhnik Y, Reinisch W, Farkkila MA, Brixi H, Seksik P, Malamut G, Coulibaly B, Dewit O, Louis E, Deplanque D, Michetti PF, Sarter H, Laharie D, Carbonnel, F, Colombel, Jf, Filippi, J, Katsanos, K, Peyrin-Biroulet, L, Allez, M, Nachury, M, Novacek, G, Danese, S, Abitbol, V, Bossa, F, Moreau, J, Bommelaer, G, Bourreille, A, Dupas, Jl, Roblin, X, Bouhnik, Y, Reinisch, W, Farkkila, Ma, Brixi, H, Seksik, P, Malamut, G, Coulibaly, B, Dewit, O, Louis, E, Deplanque, D, Michetti, Pf, Sarter, H, and Laharie, D

Published
2015

47. A negative screening does not eliminate tuberculosis risk under anti-TNF treatment in inflammatory bowel disease: a descriptive study

Author

Abitbol, Y., Laharie, D., Cosnes, J., Allez, M., Nancey, S., Amiot, Audrey, Aubourg, A., Fumery, Mathurin, Altwegg, R., Michetti, P., Chanteloup, E., Seksik, P., Abitbol, V., Baudry, C., Flamant, M., Bouguen, G., Stefanescu, C., Bourrier, A., Bommelaer, G., Dib, N., Bigard, M. A., Viennot, S., Hébuterne, X., Gornet, J. M., Marteau, P., Bouhnik, Y., Nahon, S, Service de Gastroentérologie et nutrition [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Service d’hépatogastroenterologie, CHU Amiens-Picardie, Département de gastroentérologie, Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Foie, métabolismes et cancer, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Service de gastroentérologie, MICI et assistance nutritive, pôle des maladies de l’appareil digestif, Université Paris Diderot - Paris 7 (UPD7)-Hôpital Beaujon [AP-HP], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Centre Hospitalier Universitaire de Nice (CHU de Nice), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), AP-HP, Hôpital Lariboisière, Hôpital Lariboisière-Fernand-Widal [APHP], CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7)-Hôpital Beaujon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre Hospitalier Universitaire de Nice (CHU Nice), and Université Nice Sophia Antipolis (1965 - 2019) (UNS)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience; Meeting abstract Sa1949

Published
2016
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48. P369 Efficacy of infliximab after failure of subcutaneous anti-TNF agents in patients with ulcerative colitis: A multicentre study

Author

Streichenberger, A, primary, Pariente, B, additional, Bozon, A, additional, Arab, N, additional, Amiot, A, additional, Vuitton, L, additional, Tilmant, M, additional, Nachury, M, additional, Altwegg, R, additional, Delasalle, T, additional, Gagnière, C, additional, Grégoire, B, additional, Fumery, M, additional, Wils, P, additional, Pineton de Chambrun, G, additional, Hébuterne, X, additional, Pereira, B, additional, Bommelaer, G, additional, and Buisson, A, additional

Published
2018
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