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1. The geometry of covering codes in the sum-rank metric

Author

Bonini, Matteo, Borello, Martino, and Byrne, Eimear

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory, 05B40, 11T71, 51E20, 52C17, 94B75
Abstract

We introduce the concept of a sum-rank saturating system and outline its correspondence to a covering properties of a sum-rank metric code. We consider the problem of determining the shortest sum-rank-$\rho$-saturating systems of a fixed dimension, which is equivalent to the covering problem in the sum-rank metric. We obtain upper and lower bounds on this quantity. We also give constructions of saturating systems arising from geometrical structures.

Published
2024

2. Minimal codewords in Norm-Trace codes

Author

Bartoli, Daniele, Bonini, Matteo, and Timpanella, Marco

Subjects
Mathematics - Algebraic Geometry, Computer Science - Information Theory
Abstract

In this paper, we consider the affine variety codes obtained evaluating the polynomials $by=a_kx^k+\dots+a_1x+a_0$, $b,a_i\in\mathbb{F}_{q^r}$, at the affine $\F_{q^r}$-rational points of the Norm-Trace curve. In particular, we investigate the weight distribution and the set of minimal codewords. Our approach, which uses tools of algebraic geometry, is based on the study of the absolutely irreducibility of certain algebraic varieties.

Published
2022

5. Saturating systems and the rank covering radius

Author

Bonini, Matteo, Borello, Martino, and Byrne, Eimear

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory, 05B40, 11T71, 51E20, 52C17, 94B75
Abstract

We introduce the concept of a rank saturating system and outline its correspondence to a rank-metric code with a given covering radius. We consider the problem of finding the value of $s_{q^m/q}(k,\rho)$, which is the minimum $\mathbb{F}_q$-dimension of a $q$-system in $\mathbb{F}_{q^m}^k$ which is rank $\rho$-saturating. This is equivalent to the covering problem in the rank metric. We obtain upper and lower bounds on $s_{q^m/q}(k,\rho)$ and evaluate it for certain values of $k$ and $\rho$. We give constructions of rank $\rho$-saturating systems suggested from geometry., Comment: 26 pages, to appear in Journal of Algebraic Combinatorics

Published
2022

6. Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)

Author

Bousquet, Jean, Schünemann, Holger J., Sousa-Pinto, Bernardo, Zuberbier, Torsten, Togias, Alkis, Samolinski, Boleslaw, Bedbrook, Anna, Czarlewski, Wienczyslawa, Hofmann-Apitius, Martin, Litynska, Justyna, Vieira, Rafael José, Anto, Josep M., Fonseca, Joao A., Brozek, Jan, Bognanni, Antonio, Brussino, Luisa, Canonica, G. Walter, Cherrez-Ojeda, Ivan, Cruz, Alvaro A., Vecillas, Leticia de las, Dykewicz, Mark, Gemicioglu, Bilun, Giovannini, Mattia, Haahtela, Tari, Jacobs, Marc, Jacomelli, Cristina, Klimek, Ludger, Kvedariene, Violeta, Larenas-Linnemann, Desiree E., Louis, Gilles, Lourenço, Olga, Leemann, Lucas, Morais-Almeida, Mario, Neves, Ana Luisa, Nadeau, Kari C., Nowak, Artur, Palamarchuk, Yuliia, Palkonen, Susanna, Papadopoulos, Nikolaos G., Parmelli, Elena, Pereira, Ana Margarida, Pfaar, Oliver, Regateiro, Frederico S., Savouré, Marine, Taborda-Barata, Luis, Toppila-Salmi, Sanna K., Torres, Maria J., Valiulis, Arunas, Ventura, Maria Teresa, Williams, Sian, Yepes-Nuñez, Juan J., Yorgancioglu, Arzu, Zhang, Luo, Zuberbier, Jaron, Abdul Latiff, Amir Hamzah, Abdullah, Baharudin, Agache, Ioana, Al-Ahmad, Mona, Al-Nesf, Maryam Ali, Al Shaikh, Nada A., Amaral, Rita, Ansotegui, Ignacio J., Asllani, Julijana, Balotro-Torres, Maria Cristina, Bergmann, Karl-Christian, Bernstein, Jonathan A., Bindslev-Jensen, Carsten, Blaiss, Michael S., Bonaglia, Cristina, Bonini, Matteo, Bossé, Isabelle, Braido, Fulvio, Caballero-Fonseca, Fernan, Camargos, Paulo, Carreiro-Martins, Pedro, Casale, Thomas, Castillo-Vizuete, José-Antonio, Cecchi, Lorenzo, Teixeira, Maria do Ceu, Chang, Yoon-Seok, Loureiro, Claudia Chaves, Christoff, George, Ciprandi, Giorgio, Cirule, Ieva, Correia-de-Sousa, Jaime, Costa, Elisio M., Cvetkovski, Biljana, de Vries, Govert, Del Giacco, Stefano, Devillier, Philippe, Dokic, Dejan, Douagui, Habib, Durham, Stephen R., Enecilla, Maria Lourdes, Fiocchi, Alessandro, Fokkens, Wytske J., Fontaine, Jean-François, Gawlik, Radoslaw, Gereda, Jose E., Gil-Mata, Sara, Giuliano, Antonio F.M., Gotua, Maia, Gradauskiene, Brigita, Guzman, Maria Antonieta, Hossny, Elham, Hrubiško, Martin, Iinuma, Tomohisa, Irani, Carla, Ispayeva, Zhanat, Ivancevich, Juan Carlos, Jartti, Tuomas, Jeseňák, Miloš, Julge, Kaja, Jutel, Marek, Kaidashev, Igor, Bennoor, Kazi S., Khaltaev, Nicolai, Kirenga, Bruce, Kraxner, Helga, Kull, Inger, Kulus, Marek, Kuna, Piotr, Kupczyk, Maciej, Kurchenko, Andriy, La Grutta, Stefania, Lane, Stephen, Miculinic, Neven, Lee, Sang Min, Le Thi Tuyet, Lan, Lkhagvaa, Battur, Louis, Renaud, Mahboub, Bassam, Makela, Mika, Makris, Michael, Maurer, Marcus, Melén, Eric, Milenkovic, Branislava, Mohammad, Yousser, Moniuszko, Marcin, Montefort, Stephen, Moreira, Andre, Moreno, Pablo, Mullol, Joaquim, Nadif, Rachel, Nakonechna, Alla, Navarro-Locsin, Cecilia Gretchen, Neffen, Hugo E., Nekam, Kristof, Niedoszytko, Marek, Nunes, Elizabete, Nyembue, Dieudonné, O’Hehir, Robyn, Ollert, Markus, Ohta, Ken, Okamoto, Yoshitaka, Okubo, Kimihiro, Olze, Heidi, Padukudru, Mahesh Anand, Palomares, Oscar, Pali-Schöll, Isabella, Panzner, Petr, Palosuo, Kati, Park, Hae S., Passalacqua, Giovanni, Patella, Vincenzo, Pawankar, Ruby, Pétré, Benoît, Pitsios, Constantinos, Plavec, Davor, Popov, Todor A., Puggioni, Francesca, Quirce, Santiago, Raciborski, Filip, Ramonaité, Agné, Recto, Marysia, Repka-Ramirez, Susana, Roberts, Graham, Robles-Velasco, Karla, Roche, Nicolas, Rodriguez-Gonzalez, Monica, Romualdez, Joel A., Rottem, Menachem, Rouadi, Philip W., Salapatas, Marianella, Sastre, Joaquin, Serpa, Faradiba S., Sayah, Zineb, Scichilone, Nicola, Senna, Gianenrico, Sisul, Juan Carlos, Solé, Dirceu, Soto-Martinez, Manuel E., Sova, Milan, Sozinova, Olga, Stevanovic, Katarina, Ulrik, Charlotte Suppli, Szylling, Anna, Tan, Frances M., Tantilipikorn, Pongsakorn, Todo-Bom, Ana, Tomic-Spiric, Vesna, Tsaryk, Vladyslav, Tsiligianni, Ioanna, Urrutia-Pereira, Marilyn, Rostan, Marylin Valentin, Sofiev, Mikhail, Valovirta, Erkka, Van Eerd, Michiel, Van Ganse, Eric, Vasankari, Tuula, Vichyanond, Pakit, Viegi, Giovanni, Wallace, Dana, Wang, De Yun, Waserman, Susan, Wong, Gary, Worm, Margitta, Yusuf, Osman M., Zaitoun, Fares, and Zidarn, Mihaela

Published
2024
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8. Rational points on cubic surfaces and AG codes from the Norm-Trace curve

Author

Bonini, Matteo, Sala, Massimiliano, and Vicino, Lara

Subjects
Mathematics - Algebraic Geometry, Computer Science - Information Theory
Abstract

In this paper we give a complete characterization of the intersections between the Norm-Trace curve over $\mathbb{F}_{q^3}$ and the curves of the form $y=ax^3+bx^2+cx+d$, generalizing a previous result by Bonini and Sala, providing more detailed information about the weight spectrum of one-point AG codes arising from such curve. We also derive, with explicit computations, some general bounds for the number of rational points on a cubic surface defined over $\mathbb{F}_{q}$.

Published
2021
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12. On the weight distribution of some minimal codes

Author

Bartoli, Daniele, Bonini, Matteo, and Timpanella, Marco

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory
Abstract

Minimal codes are a class of linear codes which gained interest in the last years, thanks to their connections to secret sharing schemes. In this paper we provide the weight distribution and the parameters of families of minimal codes recently introduced by C. Tang, Y. Qiu, Q. Liao, Z. Zhou, answering some open questions.

Published
2020

13. Severe Asthma Network Italy Definition of Clinical Remission in Severe Asthma: A Delphi Consensus

Author

Canonica, Giorgio Walter, Blasi, Francesco, Carpagnano, Giovanna Elisiana, Guida, Giuseppe, Heffler, Enrico, Paggiaro, Pierluigi, Allegrini, Chiara, Antonelli, Andrea, Aruanno, Arianna, Bacci, Elena, Bagnasco, Diego, Beghè, Bianca, Bonavia, Marco, Bonini, Matteo, Brussino, Luisa, Caiaffa, Maria Filomena, Calabrese, Cecilia, Camiciottoli, Gianna, Caminati, Marco, Caruso, Cristiano, Cavallini, Mirta, Chieco Bianchi, Fulvia, Conte, Maria Elisabetta, Corsico, Angelo Guido, Cosmi, Lorenzo, Costantino, Mariateresa, Costanzo, Giulia, Crivellaro, Mariaangiola, D'Alò, Simona, D'Amato, Mariella, Detoraki, Aikaterini, Di Proietto, Maria Carmela, Facciolongo, Nicola Cosimo, Ferri, Sebastian, Fierro, Vincenzo, Foschino, Maria Pia, Latorre, Manuela, Lombardi, Carlo, Macchia, Luigi, Milanese, Manlio, Montagni, Marcello, Parazzini, Elena Maria, Parente, Roberta, Passalacqua, Giovanni, Patella, Vincenzo, Pelaia, Girolamo, Pini, Laura, Puggioni, Francesca, Ricciardi, Luisa, Ridolo, Erminia, Rolo, Joyce, Scichilone, Nicola, Scioscia, Giulia, Senna, Gianenrico, Solidoro, Paolo, Varricchi, Gilda, Vianello, Andrea, Yacoub, Mona Rita, and Yang, Baoran

Published
2023
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14. Global access and patient safety in the transition to environmentally friendly respiratory inhalers: the Global Initiative for Asthma perspective

Author

Levy, Mark L, Bateman, Eric D, Allan, Keith, Bacharier, Leonard B, Bonini, Matteo, Boulet, Louis-Philippe, Bourdin, Arnaud, Brightling, Chris, Brusselle, Guy, Buhl, Roland, Chakaya, Muhwa Jeremiah, Cruz, Alvaro A, Drazen, Jeffrey, Ducharme, Francine M, Duijts, Liesbeth, Fleming, Louise, Inoue, Hiromasa, Ko, Fanny W S, Krishnan, Jerry A, Masekela, Refiloe, Mortimer, Kevin, Pitrez, Paulo, Salvi, Sundeep, Sheikh, Aziz, Reddel, Helen K, and Yorgancıoğlu, Arzu

Published
2023
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17. An inductive construction of minimal codes

Author

Bartoli, Daniele, Bonini, Matteo, and Güneş, Burçin

Subjects
Computer Science - Information Theory, Mathematics - Combinatorics
Abstract

We provide new families of minimal codes in any characteristic. Also, an inductive construction of minimal codes is presented., Comment: arXiv admin note: text overlap with arXiv:1811.06829

Published
2019

18. On the weights of dual codes arising from the GK curve

Author

Ballico, Edoardo and Bonini, Matteo

Subjects
Computer Science - Information Theory, Mathematics - Algebraic Geometry
Abstract

In this paper we investigate some dual algebraic-geometric codes associated with the Giulietti-Korchm\'aros maximal curve. We compute the minimum distance and the minimum weight codewords of such codes and we investigate the generalized hamming weights of such codes.

Published
2019

19. Minimal linear codes arising from blocking sets

Author

Bonini, Matteo and Borello, Martino

Subjects
Computer Science - Information Theory, Mathematics - Combinatorics
Abstract

Minimal linear codes are algebraic objects which gained interest in the last twenty years, due to their link with Massey's secret sharing schemes. In this context, Ashikhmin and Barg provided a useful and a quite easy to handle sufficient condition for a linear code to be minimal, which has been applied in the construction of many minimal linear codes. In this paper, we generalize some recent constructions of minimal linear codes which are not based on Ashikhmin-Barg's condition. More combinatorial and geometric methods are involved in our proofs. In particular, we present a family of codes arising from particular blocking sets, which are well-studied combinatorial objects. In this context, we will need to define cutting blocking sets and to prove some of their relations with other notions in blocking sets' theory. At the end of the paper, we provide one explicit family of cutting blocking sets and related minimal linear codes, showing that infinitely many of its members do not satisfy the Ashikhmin-Barg's condition., Comment: 13 pages

Published
2019

20. Planar Polynomials arising from Linearized polynomials

Author

Bartoli, Daniele and Bonini, Matteo

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory, 05B10, 05B25, 51A35, 94A60
Abstract

In this paper we construct planar polynomials of the type $f_{A,B}(x)=x(x^{q^2}+Ax^{q}+Bx)\in \mathbb{F}_{q^3}[x]$, with $A,B \in \mathbb{F}_{q}$. In particular we completely classify the pairs $(A,B)\in \mathbb{F}_{q}^2$ such that $f_{A,B}(x)$ is planar using connections with algebraic curves over finite fields.

Published
2019

22. Intersections between the norm-trace curve and some low degree curves

Author

Bonini, Matteo and Sala, Massimiliano

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory, Mathematics - Algebraic Geometry, 14G50 - 11T71 - 94B27
Abstract

In this paper we analyze the intersection between the norm-trace curve over $\mathbb{F}_{q^3}$ and the curves of the form $y=ax^3+bx^2+cx+d$, giving a complete characterization of the intersection between the curve and the parabolas, as well as sharp bounds for the other cases. This information is used for the determination of the weight distribution of some one-point AG codes constructed on the curve.

Published
2018

23. Development and validation of an electronic daily control score for asthma (e-DASTHMA): a real-world direct patient data study

Author

Sousa-Pinto, Bernardo, Jácome, Cristina, Pereira, Ana Margarida, Regateiro, Frederico S, Almeida, Rute, Czarlewski, Wienczyslawa, Kulus, Marek, Shamji, Mohamed H, Boulet, Louis-Philippe, Bonini, Matteo, Brussino, Luisa, Canonica, G Walter, Cruz, Alvaro A, Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée, Louis, Renaud, Niedoszytko, Marek, Pham-Thi, Nhân, Puggioni, Francesca, Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Vieira, Rafael José, Agache, Ioana, Bedbrook, Anna, Bergmann, Karl C, Amaral, Rita, Azevedo, Luís Filipe, Bosnic-Anticevich, Sinthia, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Loureiro, Claudia Chaves, de Blay, Frédéric, Del Giacco, Stefano, Devillier, Philippe, Jassem, Ewa, Joos, Guy, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Luna Pech, Jorge, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Neffen, Hugo E, Ohta, Ken, Papadopoulos, Nikolaos G, Papi, Alberto, Pétré, Benoit, Pfaar, Oliver, Yeverino, Daniela Rivero, Cordeiro, Carlos Robalo, Roche, Nicolas, Sá-Sousa, Ana, Samolinski, Boleslaw, Sheikh, Aziz, Ulrik, Charlotte Suppli, Usmani, Omar S, Valiulis, Arunas, Vandenplas, Olivier, Vieira-Marques, Pedro, Yorgancioglu, Arzu, Zuberbier, Torsten, Anto, Josep M, Fonseca, João A, and Bousquet, Jean

Published
2023
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25. Minimal linear codes in odd characteristic

Author

Bartoli, Daniele and Bonini, Matteo

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory, 94B05, 94C10, 94A60
Abstract

In this paper we generalize constructions in two recent works of Ding, Heng, Zhou to any field $\mathbb{F}_q$, $q$ odd, providing infinite families of minimal codes for which the Ashikhmin-Barg bound does not hold.

Published
2018

26. Minimum weight codewords in dual Algebraic-Geometric codes from the Giulietti-Korchm\'aros curve

Author

Bartoli, Daniele and Bonini, Matteo

Subjects
Mathematics - Combinatorics, Computer Science - Information Theory
Abstract

In this paper we investigate the number of minimum weight codewords of some dual Algebraic-Geometric codes associated with the Giulietti-Korchm\'aros maximal curve, by computing the maximal number of intersections between the Giulietti-Korchm\'aros curve and lines, plane conics and plane cubics.

Published
2018

27. On plane curves given by separated polynomials and their automorphisms

Author

Bonini, Matteo, Montanucci, Maria, and Zini, Giovanni

Subjects
Mathematics - Algebraic Geometry
Abstract

Let $\mathcal{C}$ be a plane curve defined over the algebraic closure $K$ of a prime finite field $\mathbb{F}_p$ by a separated polynomial, that is $\mathcal{C}: A(y)=B(x)$, where $A(y)$ is an additive polynomial of degree $p^n$ and the degree $m$ of $B(X)$ is coprime with $p$. Plane curves given by separated polynomials are well-known and studied in the literature. However just few informations are known on their automorphism groups. In this paper we compute the full automorphism group of $\mathcal{C}$ when $m \not\equiv 1 \pmod {p^n}$ and $B(X)$ has just one root in $K$, that is $B(X)=b_m(X+b_{m-1}/mb_m)^m$ for some $b_m,b_{m-1} \in K$. Moreover, some sufficient conditions for the automorphism group of $\mathcal{C}$ to imply that $B(X)=b_m(X+b_{m-1}/mb_m)^m$ are provided. As a byproduct, the full automorphism group of the Norm-Trace curve $\mathcal{C}: x^{(q^r-1)/(q-1)}=y^{q^{r-1}}+y^{q^{r-2}}+\ldots+y$ is computed. Finally, these results are used to construct multi point AG codes with many automorphisms.

Published
2017

28. Asthma remission one, none and one-hundred thousand: the relevance of the patient's view.

Author

Bonini, Matteo, Barbaglia, Simona, Camiciottoli, Gianna, Del Giacco, Stefano, Di Marco, Fabiano, Matucci, Andrea, Micheletto, Claudio, Papi, Alberto, Pasqualetti, Patrizio, Pelaia, Girolamo, Ricciardolo, Fabio Luigi Massimo, Rogliani, Paola, Senna, Gianenrico, Triggiani, Massimo, Vancheri, Carlo, and Canonica, Giorgio Walter

Subjects
*PATIENTS' attitudes, *THERAPEUTIC alliance, *PATIENT preferences, *DISEASE management, *INDIVIDUALIZED medicine
Abstract

Objective: Achieving remission in severe asthma holds paramount importance in elevating patient quality of life and reducing both individual and societal burdens associated with this chronic condition. This study centers on identifying pivotal patient-relevant endpoints through standardized, reproducible methods, while also developing a patient-centric definition of remission, essential for effective disease management. Methods: A discrete choice experiment (DCE) was conducted to assess patients' perceptions on the four primary criteria for defining severe asthma remission, as outlined by the SANI survey. Additionally, it investigated the correlation between these perceptions and improvements in the doctor-patient therapeutic alliance during treatment decision-making. Results: 249 patients (70% aged between 31–60, 59% women and 82% without other pathologies requiring corticosteroids) prioritize the use of oral corticosteroids (OCS, 48%) and the Asthma Control Test (ACT, 27%) in defining their condition, ranking these above lung function and exacerbations. This preference for OCS stems from its direct role in treatment, tangible tracking, immediate symptom relief, and being a concrete measure of disease severity compared to the less predictable and quantifiable exacerbations. Conclusions: This study explores severe asthma remission from patients' perspectives using clinician-evaluated parameters. The DCE revealed that most patients highly value OCS and the ACT, prefer moderate improvement, and avoid cortisone cycles. No definitive preference was found for lung function status. Integrating patient-reported information with professional insights is crucial for effective management and future research. Personalized treatment plans focusing on patient preferences, adherence, and alternative therapies aim to achieve remission and enhance quality of life. [ABSTRACT FROM AUTHOR]

Published
2024
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29. The Impact of Lung Function on Sleep Monitoring in Obstructive Sleep Apnea Associated with Obstructive Lung Diseases: Insights from a Clinical Study.

Author

Fabozzi, Antonio, Steffanina, Alessia, Nicolai, Ambra, Olmati, Federica, Bonini, Matteo, and Palange, Paolo

Subjects
OBSTRUCTIVE lung diseases, CHRONIC obstructive pulmonary disease, FORCED expiratory volume, SLEEP apnea syndromes, PULMONARY function tests
Abstract

Background/Objectives: Obstructive sleep apnea (OSA) and obstructive lung diseases (OLD) are common and interdependent respiratory disorders, where one condition may contribute to the development and worsening of the other (OLDOSA syndrome). The term OLDOSA syndrome includes two different conditions: Overlap syndrome (OVS: OSA + chronic obstructive pulmonary disease, COPD) and Alternative Overlap syndrome (aOVS: OSA + Asthma). Data on the interactions between lung function and respiratory monitoring during sleep in OLDOSA patients are few and controversial. Our study aims to evaluate the impact of lung function impairment on sleep breathing disorders, paying attention to the lack of literature about comparisons between OVS, aOVS, and the impact of small airways disease (SAD) in these patients. Methods: In total, 101 patients with a diagnosis of OSA and asthma or COPD underwent pulmonary function tests (PFTs) and nocturnal home sleep cardiorespiratory monitoring (HSCM). Exclusion criteria: Obesity hypoventilation syndrome (OHS) and other non-respiratory sleep disorders. Results: Sleep time with oxygen saturation below 90% (T90) was negatively correlated with forced expiratory volume in the first second, % of predicted (%FEV1), forced vital capacity, % of predicted (%FVC), forced expiratory flow at 25–75% of the pulmonary volume, % of predicted (%FEF25–75), and, after multivariable linear regression analysis, %FEF25–75 remained an independent factor for T90 with a negative correlation in mild and moderate OSA. Obstructive apnea index (oAI) and FEV1/FVC were negatively correlated in mild and moderate OSA. OVS presented with more severe OSA (higher AHI, oAI, and T90) and SAD (lower FEF25–75) compared to aOVS. Conclusions: This study highlights a possible interdependence between OLD and OSA; obstruction of the large and small airways at PFTs contributes to the worsening of these patients' nocturnal hypoxemia and obstructive events of the upper airway during sleep. Furthermore, this study shows that patients with OVS should be carefully monitored, as they present worse data at HSCM and have greater small airways involvement compared to aOVS. [ABSTRACT FROM AUTHOR]

Published
2024
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30. Sinonasal Outcomes Obtained after 2 Years of Treatment with Benralizumab in Patients with Severe Eosinophilic Asthma and CRSwNP: A "Real-Life" Observational Study.

Author

De Corso, Eugenio, Mele, Dario Antonio, Rizzi, Angela, Spanu, Camilla, Corbò, Marco, Pisciottano, Serena, Mastrapasqua, Rodolfo Francesco, Baroni, Silvia, Porru, Davide Paolo, De Maio, Gabriele, Rizzuti, Alberta, Di Bella, Giuseppe Alberto, Ortolan, Augusta, Bonini, Matteo, Cefaloni, Francesca, Boccabella, Cristina, Lombardi, Francesco, Chini, Raffaella, Caruso, Cristiano, and Panfili, Marco

Subjects
PARANASAL sinuses, ANTI-inflammatory agents, INTERLEUKIN-5, EOSINOPHILS, QUALITY of life, ENDOSCOPIC surgery, NASAL polyps
Abstract

Background/Objectives: Benralizumab is a monoclonal antibody that targets the interleukin-5 receptor (IL-5Rα), leading to the rapid depletion of blood eosinophils. RCTs have demonstrated efficacy in patients with severe eosinophilic asthma (SEA). The aim of this study was to assess the efficacy of benralizumab on sinonasal outcomes in a real-life setting in patients with SEA and concomitant chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: We included 25 patients (mean age: 57.47 years, range: 35–77, F/M = 12:13) who were prescribed 30 mg benralizumab every month for the first three administrations and then every 2 months. The primary endpoint was to evaluate changes in the SinoNasal Outcome Test-22 (SNOT-22) and nasal polyp score (NPS) over a 24-month treatment period. Secondary endpoints included measuring the effects on nasal obstruction and impaired sense of smell. Results: The mean NPS score decreased significantly from 5.11 ± 1.84 at baseline to 2.37 ± 1.96 at 24 months. The mean SNOT-22 decreased from 57 ± 15.30 at baseline to 26 ± 16.73 at 24 months. The SSIT-16 mean score improved with an increase in olfactory performance from 5.23 ± 2.58 at baseline to 7 ± 3.65 at 24 months. Moreover, 8/25 patients (32%) required rescue treatment with systemic steroids and 2 patients required endoscopic sinus surgery. Conclusions: While the improvement may not seem optimal at 12 months, a progressive enhancement was noted during the second year of treatment. Despite our data showing an improvement in quality of life and a reduction in the size of nasal polyps, no significant improvement in olfactory sensitivity was observed. In addition, in several patients, rescue treatments were required to maintain control of nasal and sinus symptoms. A careful risk–benefit assessment is therefore needed when deciding to continue treatment, weighing the potential for further improvement against the risks of complications. Such decisions should always be made in the context of a multidisciplinary team. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Asthma

Author

Bonini, Matteo, Cogo, Annalisa, editor, Bonini, Matteo, editor, and Onorati, Paolo, editor

Published
2019
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32. Severe asthma: One disease and multiple definitions

Author

Guarnieri, Gabriella, Patella, Vincenzo, Maria Pia, Foschino Barbaro, Carpagnano, Giovanna Elisiana, Colle, Anna del, Scioscia, Giulia, Gerolamo, Pelaia, Puggioni, Francesca, Racca, Francesca, Favero, Elisabetta, Iannacone, Sandra, Savi, Eleonora, Montagni, Marcello, Camiciottoli, Gianna, Allegrini, Chiara, Lombardi, Carlo, Spadaro, Giuseppe, Detoraki, Caterina, Menzella, Francesco, Galeone, Carla, Ruggiero, Patrizia, Yacoub, Monna Rita, Berti, Alvise, Scichilone, Nicola, Durante, Carmen, Costantino, Maria Teresa, Roncallo, Chiara, Braschi, Mariachiara, D’Adda, Alice, Ridolo, Erminia, Triggiani, Massimo, Parente, Roberta, Maria, D’Amato, Verrillo, Maria Vittoria, Rolla, Giovanni, Brussino, Luisa, Frazzetto, Agata Valentina, Cristina, Zappa Maria, Lilli, Marianna, Crimi, Nunzio, Bonavia, Marco, Corsico, Angelo Guido, Grosso, Amelia, Del Giacco, Stefano, Deidda, Margherita, Ricciardi, Luisa, Isola, Stefania, Cicero, Francesca, Amato, Giuliana, Vita, Federica, Spanevello, Antonio, Pignatti, Patrizia, Cherubino, Francesca, Visca, Dina, Massimo Ricciardolo, Fabio Luigi, Anna Carriero, Vitina Maria, Bertolini, Francesca, Santus, Pierachille, Barlassina, Roberta, Airoldi, Andrea, Guida, Giuseppe, Eleonora, Nucera, Aruanno, Arianna, Rizzi, Angela, Caruso, Cristiano, Colantuono, Stefania, Senna, Gianenrico, Caminati, Marco, Arcolaci, Alessandra, Vianello, Andrea, Bianchi, Fulvia Chieco, Marchi, Maria Rita, Centanni, Stefano, Luraschi, Simone, Ruggeri, Silvia, Rinaldo, Rocco, Parazzini, Elena, Calabrese, Cecilia, Flora, Martina, Cosmi, Lorenzo, Di Pietro, Linda, Maggi, Enrico, Pini, Laura, Macchia, Luigi, Di Bona, Danilo, Richeldi, Luca, Condoluci, Carola, Fuso, Leonello, Bonini, Matteo, Farsi, Alessandro, Carli, Giulia, Montuschi, Paolo, Santini, Giuseppe, Conte, Maria Elisabetta, Turchet, Elisa, Barbetta, Carlo, Mazza, Francesco, D’Alo, Simona, Pucci, Stefano, Caiaffa, Maria Filomena, Minenna, Elena, D'Elia, Luciana, Pasculli, Carlo, Viviano, Vittorio, Tarsia, Paolo, Rolo, Joyce, Di Proietto, Mariacarmela, Lo Cicero, Salvatore, Bagnasco, Diego, Paggiaro, Pierluigi, Latorre, Manuela, Folli, Chiara, Testino, Elisa, Bassi, Arianna, Milanese, Manlio, Heffler, Enrico, Manfredi, Andrea, Riccio, Anna Maria, De Ferrari, Laura, Blasi, Francesco, Canevari, Rikki Frank, Canonica, Giorgio Walter, and Passalacqua, Giovanni

Published
2021
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34. Economic impact of mepolizumab in uncontrolled severe eosinophilic asthma, in real life

Author

Guarnieri, Gabriella, Patella, Vincenzo, Maria Pia, Foschino Barbaro, Carpagnano, Elisiana, Colle, Anna del, Scioscia, Giulia, Gerolamo, Pelaia, Paggiaro, Pierluigi, Latorre, Manuela, Puggioni, Francesca, Racca, Francesca, Favero, Elisabetta, Iannacone, Sandra, Savi, Eleonora, Montagni, Marcello, Camiciottoli, Gianna, Allegrini, Chiara, Spadaro, Giuseppe, Detoraki, Caterina, Galeone, Carla, Ruggiero, Patrizia, Yacoub, Monna Rita, Berti, Alvise, Colombo, Gisella, Scichilone, Nicola, Durante, Carmen, Costantino, Maria Teresa, Roncallo, Chiara, Braschi, Mariachiara, Blasi, Francesco, D'Adda, Alice, Ridolo, Erminia, Triggiani, Massimo, Parente, Roberta, Maria, D'Amato, Verrillo, Maria Vittoria, Cristina, Zappa Maria, Lilli, Marianna, Crimi, Nunzio, Bonavia, Marco, Corsico, Angelo Guido, Grosso, Amelia, Del Giacco, Stefano, Deidda, Margherita, Ricciardi, Luisa, Isola, Stefania, Cicero, Francesca, Amato, Giuliana, Vita, Federica, Spanevello, Antonio, Pignatti, Patrizia, Cherubino, Francesca, Visca, Dina, Aletti, Eleonora, Massimo Ricciardolo, Fabio Luigi, Anna Carriero, Vitina Maria, Bertolini, Francesca, Santus, Pierachille, Barlassina, Roberta, Airoldi, Andrea, Guida, Giuseppe, Eleonora, Nucera, Aruanno, Arianna, Rizzi, Angela, Caruso, Cristiano, Colantuono, Stefania, Arcolaci, Alessandra, Vianello, Andrea, Bianchi, Fulvia Chieco, Marchi, Maria Rita, Centanni, Stefano, Luraschi, Simone, Ruggeri, Silvia, Rinaldo, Rocco, Parazzini, Elena, Calabrese, Cecilia, Flora, Martina, Cosmi, Lorenzo, Di Pietro, Linda, Maggi, Enrico, Pini, Laura, Macchia, Luigi, Di Bona, Danilo, Richeldi, Luca, Condoluci, Carola, Fuso, Leonello, Bonini, Matteo, Farsi, Alessandro, Carli, Giulia, Montuschi, Paolo, Santini, Giuseppe, Conte, Maria Elisabetta, Turchet, Elisa, Barbetta, Carlo, Mazza, Francesco, D'Alo, Simona, Pucci, Stefano, Caiaffa, Maria Filomena, Minenna, Elena, D'Elia, Luciana, Pasculli, Carlo, Viviano, Vittorio, Tarsia, Paolo, Rolo, Joyce, Di Proietto, Mariacarmela, Lo Cicero, Salvatore, Bagnasco, Diego, Povero, Massimiliano, Pradelli, Lorenzo, Brussino, Luisa, Rolla, Giovanni, Caminati, Marco, Menzella, Francesco, Heffler, Enrico, Canonica, Giorgio Walter, Senna, Gianenrico, Milanese, Manlio, Lombardi, Carlo, Bucca, Caterina, Manfredi, Andrea, Canevari, Rikki Frank, and Passalacqua, Giovanni

Published
2021
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35. Relevance of individual bronchial symptoms for asthma diagnosis and control in patients with rhinitis:A MASK-air study

Author

Sousa-Pinto, Bernardo, Louis, Gilles, Vieira, Rafael J., Czarlewski, Wienczyslawa, Anto, Josep M., Amaral, Rita, Sá-Sousa, Ana, Brussino, Luisa, Canonica, G. Walter, Loureiro, Claudia Chaves, Cruz, Alvaro A., Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée E., Pham-Thi, Nhân, Puggioni, Francesca, Regateiro, Frederico S., Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Agache, Ioana, Bedbrook, Anna, Benfante, Alida, Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Bonini, Matteo, Boulet, Louis Philippe, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Costa, Elisio M., Del Giacco, Stefano, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Papi, Alberto, Pfaar, Oliver, Rivero-Yeverino, Daniela, Ulrik, Charlotte Suppli, Sousa-Pinto, Bernardo, Louis, Gilles, Vieira, Rafael J., Czarlewski, Wienczyslawa, Anto, Josep M., Amaral, Rita, Sá-Sousa, Ana, Brussino, Luisa, Canonica, G. Walter, Loureiro, Claudia Chaves, Cruz, Alvaro A., Gemicioglu, Bilun, Haahtela, Tari, Kupczyk, Maciej, Kvedariene, Violeta, Larenas-Linnemann, Desirée E., Pham-Thi, Nhân, Puggioni, Francesca, Regateiro, Frederico S., Romantowski, Jan, Sastre, Joaquin, Scichilone, Nicola, Taborda-Barata, Luis, Ventura, Maria Teresa, Agache, Ioana, Bedbrook, Anna, Benfante, Alida, Bergmann, Karl C., Bosnic-Anticevich, Sinthia, Bonini, Matteo, Boulet, Louis Philippe, Brusselle, Guy, Buhl, Roland, Cecchi, Lorenzo, Charpin, Denis, Costa, Elisio M., Del Giacco, Stefano, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Laune, Daniel, Makela, Mika, Morais-Almeida, Mario, Nadif, Rachel, Niedoszytko, Marek, Papadopoulos, Nikolaos G., Papi, Alberto, Pfaar, Oliver, Rivero-Yeverino, Daniela, and Ulrik, Charlotte Suppli

Abstract

Rationale It is unclear how each individual asthma symptom is associated with asthma diagnosis or control. Objectives To assess the performance of individual asthma symptoms in the identification of patients with asthma and their association with asthma control. Methods In this cross-sectional study, we assessed real-world data using the MASK-air® app. We compared the frequency of occurrence of five asthma symptoms (dyspnea, wheezing, chest tightness, fatigue and night symptoms, as assessed by the Control of Allergic Rhinitis and Asthma Test [CARAT] questionnaire) in patients with probable, possible or no current asthma. We calculated the sensitivity, specificity and predictive values of each symptom, and assessed the association between each symptom and asthma control (measured using the e-DASTHMA score). Results were validated in a sample of patients with a physician-established diagnosis of asthma. Measurement and Main Results We included 951 patients (2153 CARAT assessments), with 468 having probable asthma, 166 possible asthma and 317 no evidence of asthma. Wheezing displayed the highest specificity (90.5%) and positive predictive value (90.8%). In patients with probable asthma, dyspnea and chest tightness were more strongly associated with asthma control than other symptoms. Dyspnea was the symptom with the highest sensitivity (76.1%) and the one consistently associated with the control of asthma as assessed by e-DASTHMA. Consistent results were observed when assessing patients with a physician-made diagnosis of asthma. Conclusions Wheezing and chest tightness were the asthma symptoms with the highest specificity for asthma diagnosis, while dyspnea displayed the highest sensitivity and strongest association with asthma control., Rationale: It is unclear how each individual asthma symptom is associated with asthma diagnosis or control. Objectives: To assess the performance of individual asthma symptoms in the identification of patients with asthma and their association with asthma control. Methods: In this cross-sectional study, we assessed real-world data using the MASK-air® app. We compared the frequency of occurrence of five asthma symptoms (dyspnea, wheezing, chest tightness, fatigue and night symptoms, as assessed by the Control of Allergic Rhinitis and Asthma Test [CARAT] questionnaire) in patients with probable, possible or no current asthma. We calculated the sensitivity, specificity and predictive values of each symptom, and assessed the association between each symptom and asthma control (measured using the e-DASTHMA score). Results were validated in a sample of patients with a physician-established diagnosis of asthma. Measurement and Main Results: We included 951 patients (2153 CARAT assessments), with 468 having probable asthma, 166 possible asthma and 317 no evidence of asthma. Wheezing displayed the highest specificity (90.5%) and positive predictive value (90.8%). In patients with probable asthma, dyspnea and chest tightness were more strongly associated with asthma control than other symptoms. Dyspnea was the symptom with the highest sensitivity (76.1%) and the one consistently associated with the control of asthma as assessed by e-DASTHMA. Consistent results were observed when assessing patients with a physician-made diagnosis of asthma. Conclusions: Wheezing and chest tightness were the asthma symptoms with the highest specificity for asthma diagnosis, while dyspnea displayed the highest sensitivity and strongest association with asthma control.

Published
2024

36. Recommendations for asthma monitoring in children:A PeARL document endorsed by APAPARI, EAACI, INTERASMA, REG, and WAO

Author

Papadopoulos, Nikolaos G., Custovic, Adnan, Deschildre, Antoine, Gern, James E., Nieto Garcia, Antonio, Miligkos, Michael, Phipatanakul, Wanda, Wong, Gary, Xepapadaki, Paraskevi, Agache, Ioana, Arasi, Stefania, Awad El-Sayed, Zeinab, Bacharier, Leonard B., Bonini, Matteo, Braido, Fulvio, Caimmi, Davide, Castro-Rodriguez, Jose A., Chen, Zhimin, Clausen, Michael, Craig, Timothy, Diamant, Zuzana, Ducharme, Francine M., Ebisawa, Motohiro, Eigenmann, Philippe, Feleszko, Wojciech, Fierro, Vincezo, Fiocchi, Alessandro, Garcia-Marcos, Luis, Goh, Anne, Gómez, René Maximiliano, Gotua, Maia, Hamelmann, Eckard, Hedlin, Gunilla, Hossny, Elham M., Ispayeva, Zhanat, Jackson, Daniel J., Jartti, Tuomas, Jeseňák, Miloš, Kalayci, Omer, Kaplan, Alan, Konradsen, Jon R., Kuna, Piotr, Lau, Susanne, Le Souef, Peter, Lemanske, Robert F., Levin, Michael, Makela, Mika J., Mathioudakis, Alexander G., Mazulov, Oleksandr, Morais-Almeida, Mário, Murray, Clare, Nagaraju, Karthik, Novak, Zoltan, Pawankar, Ruby, Pijnenburg, Marielle W., Pite, Helena, Pitrez, Paulo M., Pohunek, Petr, Price, David, Priftanji, Alfred, Ramiconi, Valeria, Rivero Yeverino, Daniela, Roberts, Graham, Sheikh, Aziz, Shen, Kun Ling, Szepfalusi, Zsolt, Tsiligianni, Ioanna, Turkalj, Mirjana, Turner, Steve, Umanets, Tetiana, Valiulis, Arunas, Vijveberg, Susanne, Wang, Jiu Yao, Winders, Tonya, Yon, Dong Keon, Yusuf, Osman M., Zar, Heather J., Papadopoulos, Nikolaos G., Custovic, Adnan, Deschildre, Antoine, Gern, James E., Nieto Garcia, Antonio, Miligkos, Michael, Phipatanakul, Wanda, Wong, Gary, Xepapadaki, Paraskevi, Agache, Ioana, Arasi, Stefania, Awad El-Sayed, Zeinab, Bacharier, Leonard B., Bonini, Matteo, Braido, Fulvio, Caimmi, Davide, Castro-Rodriguez, Jose A., Chen, Zhimin, Clausen, Michael, Craig, Timothy, Diamant, Zuzana, Ducharme, Francine M., Ebisawa, Motohiro, Eigenmann, Philippe, Feleszko, Wojciech, Fierro, Vincezo, Fiocchi, Alessandro, Garcia-Marcos, Luis, Goh, Anne, Gómez, René Maximiliano, Gotua, Maia, Hamelmann, Eckard, Hedlin, Gunilla, Hossny, Elham M., Ispayeva, Zhanat, Jackson, Daniel J., Jartti, Tuomas, Jeseňák, Miloš, Kalayci, Omer, Kaplan, Alan, Konradsen, Jon R., Kuna, Piotr, Lau, Susanne, Le Souef, Peter, Lemanske, Robert F., Levin, Michael, Makela, Mika J., Mathioudakis, Alexander G., Mazulov, Oleksandr, Morais-Almeida, Mário, Murray, Clare, Nagaraju, Karthik, Novak, Zoltan, Pawankar, Ruby, Pijnenburg, Marielle W., Pite, Helena, Pitrez, Paulo M., Pohunek, Petr, Price, David, Priftanji, Alfred, Ramiconi, Valeria, Rivero Yeverino, Daniela, Roberts, Graham, Sheikh, Aziz, Shen, Kun Ling, Szepfalusi, Zsolt, Tsiligianni, Ioanna, Turkalj, Mirjana, Turner, Steve, Umanets, Tetiana, Valiulis, Arunas, Vijveberg, Susanne, Wang, Jiu Yao, Winders, Tonya, Yon, Dong Keon, Yusuf, Osman M., and Zar, Heather J.

Abstract

Monitoring is a major component of asthma management in children. Regular monitoring allows for diagnosis confirmation, treatment optimization, and natural history review. Numerous factors that may affect disease activity and patient well-being need to be monitored: response and adherence to treatment, disease control, disease progression, comorbidities, quality of life, medication side-effects, allergen and irritant exposures, diet and more. However, the prioritization of such factors and the selection of relevant assessment tools is an unmet need. Furthermore, rapidly developing technologies promise new opportunities for closer, or even “real-time,” monitoring between visits. Following an approach that included needs assessment, evidence appraisal, and Delphi consensus, the PeARL Think Tank, in collaboration with major international professional and patient organizations, has developed a set of 24 recommendations on pediatric asthma monitoring, to support healthcare professionals in decision-making and care pathway design. (Figure presented.).

Published
2024

37. A survey study on antibiotic prescription practices for acute asthma exacerbations:An European academy of allergy and clinical immunology task force report

Author

Redel, Anne Lotte, Feleszko, Wojciech, Arcolaci, Alessandra, Cefaloni, Francesca, Atanaskovic-Markovic, Marina, Braunstahl, Gert Jan, Boccabella, Cristina, Bonini, Matteo, Karavelia, Aspasia, Louwers, Eefje, Mülleneisen, Norbert, O'Mahony, Liam, Pini, Laura, Rapiejko, Anna, Shehu, Esmeralda, Sokolowska, Milena, Untersmayr, Eva, Tramper-Stranders, Gerdien, Redel, Anne Lotte, Feleszko, Wojciech, Arcolaci, Alessandra, Cefaloni, Francesca, Atanaskovic-Markovic, Marina, Braunstahl, Gert Jan, Boccabella, Cristina, Bonini, Matteo, Karavelia, Aspasia, Louwers, Eefje, Mülleneisen, Norbert, O'Mahony, Liam, Pini, Laura, Rapiejko, Anna, Shehu, Esmeralda, Sokolowska, Milena, Untersmayr, Eva, and Tramper-Stranders, Gerdien

Abstract

Introduction: Guidelines recommend treating asthma exacerbations (AAEs) with bronchodilators combined with inhaled and/or systemic corticosteroids. Indications for antibiotic prescriptions for AAEs are usually not incorporated although the literature shows antibiotics are frequently prescribed. Aim: To investigate the antibiotic prescription rates in AAEs and explore the possible determining factors of those practices. Methods: A digital survey was created to determine the antibiotic prescription rates in AAEs and the influencing factors for the prescription practices. The survey was distributed among European academy of allergy and clinical immunology (EAACI) members by mass emailing and through regional/national societies in the Netherlands, Italy, Greece, and Poland. Furthermore, we retrieved local antibiotic prescription rates. Results: In total, 252 participants completed the survey. Respondents stated that there is a lack of guidelines to prescribe antibiotics in AAEs. The median antibiotic prescription rate in this study was 19% [IQR: 0%–40%] and was significantly different between 4 professions: paediatrics 0% [IQR: 0%–37%], pulmonologists 25% [IQR: 10%–50%], general practitioners 25% [IQR: 0%–50%], and allergologists 17% [IQR: 0%–33%]) (p = 0.046). Additional diagnostic tests were performed in 71.4% of patients before prescription and the most common antibiotic classes prescribed were macrolides (46.0%) and penicillin (42.9%). Important clinical factors for health care providers to prescribe antibiotics were colorised/purulent sputum, abnormal lung sounds during auscultation, fever, and presence of comorbidities. Conclusion:In 19% of patients with AAEs, antibiotics were prescribed in various classes with a broad range among different subspecialities. This study stresses the urgency to compose evidence-based guidelines to aim for more rational antibiotic pres

Published
2024

38. Constant dimension codes from Riemann-Roch spaces

Author

Bartoli, Daniele, Bonini, Matteo, and Giulietti, Massimo

Subjects
Computer Science - Information Theory, Mathematics - Algebraic Geometry, Mathematics - Combinatorics
Abstract

Some families of constant dimension codes arising from Riemann-Roch spaces associated to particular divisors of a curve $\X$ are constructed. These families are generalizations of the one constructed by Hansen, Comment: 10 pages

Published
2015

43. Oral CorticoSteroid sparing with biologics in severe asthma: A remark of the Severe Asthma Network in Italy (SANI)

Author

Canonica, Giorgio Walter, Blasi, Francesco, Paggiaro, Pierluigi, Senna, Gianenrico, Passalacqua, Giovanni, Spanevello, Antonio, Aliberti, Stefano, Bagnasco, Diego, Bonavia, Marco, Bonini, Matteo, Brussino, Luisa, Bucca, Caterina, Caiaffa, Maria F., Calabrese, Cecilia, Camiciottoli, Gianna, Caminati, Marco, Carpagnano, Giovanna E., Caruso, Cristiano, Centanni, Stefano, Conte, Maria E., Corsico, Angelo G., Cosmi, Lorenzo, Costantino, Maria T., Crimi, Nunzio, D’Alò, Simona, D'Amato, Maria, Del Giacco, Stefano, Farsi, Alessandro, Favero, Elisabetta, Foschino Barbaro, Maria P., Guarnieri, Gabriella, Guida, Giuseppe, Latorre, Manuela, Lo Cicero, Salvatore, Lombardi, Carlo, Macchia, Luigi, Mazza, Francesco, Menzella, Francesco, Milanese, Manlio, Montagni, Marcello, Montuschi, Paolo, Nucera, Eleonora, Parente, Roberta, Patella, Vincenzo, Pelaia, Girolamo, Pini, Laura, Puggioni, Francesca, Ricciardi, Luisa, Ricciardolo, Fabio L.M., Richeldi, Luca, Ridolo, Erminia, Rolla, Giovanni, Santus, Pierachille, Scichilone, Nicola, Spadaro, Giuseppe, Vianello, Andrea, Viviano, Vittorio, Yacoub, Mona R., Zappa, Maria C., and Heffler, Enrico

Published
2020
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44. Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden

Author

Taam, Rola Abou, Azuara, Hugo, Brouard, Jacques, Cros, Pierrick, De Lira, Cindy, Dubus, Jean-Christophe, Dunder, Teija, Efendieva, Kamilla, Egron, Carole, Emeryk, Andrzej, Huerta Villalobos, Yunuen R., Karen, Nidia, Le Roux, Pascal, Levina, Julia, Medley, Monica, Najaraju, Major, Yeverino, Daniela Rivero, Ruotsalainen, Marja, Szefler, Stanley, Schweitzer, Cyril, Benhumea, Berenice Velasco, Villarreal, Rosalaura, Weiss, Laurence, Zawadzka-Krajewska, Anna, Papadopoulos, Nikolaos G., Custovic, Adnan, Deschildre, Antoine, Mathioudakis, Alexander G., Phipatanakul, Wanda, Wong, Gary, Xepapadaki, Paraskevi, Agache, Ioana, Bacharier, Leonard, Bonini, Matteo, Castro-Rodriguez, Jose A., Chen, Zhimin, Craig, Timothy, Ducharme, Francine M., El-Sayed, Zeinab Awad, Feleszko, Wojciech, Fiocchi, Alessandro, Garcia-Marcos, Luis, Gern, James E., Goh, Anne, Gómez, René Maximiliano, Hamelmann, Eckard H., Hedlin, Gunilla, Hossny, Elham M., Jartti, Tuomas, Kalayci, Omer, Kaplan, Alan, Konradsen, Jon, Kuna, Piotr, Lau, Susanne, Le Souef, Peter, Lemanske, Robert F., Mäkelä, Mika J., Morais-Almeida, Mário, Murray, Clare, Nagaraju, Karthik, Namazova-Baranova, Leyla, Garcia, Antonio Nieto, Yusuf, Osman M., Pitrez, Paulo M.C., Pohunek, Petr, Pozo Beltrán, Cesar Fireth, Roberts, Graham C., Valiulis, Arunas, and Zar, Heather J.

Published
2020
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45. Effectiveness of myAirCoach: A mHealth Self-Management System in Asthma

Author

Khusial, Rishi J., Honkoop, Persijn J., Usmani, Omar, Soares, Marcia, Simpson, Andrew, Biddiscombe, Martyn, Meah, Sally, Bonini, Matteo, Lalas, Antonios, Polychronidou, Eleftheria, Koopmans, Julia G., Moustakas, Konstantinos, Snoeck-Stroband, Jiska B., Ortmann, Steffen, Votis, Konstantinos, Tzovaras, Dimitrios, Chung, Kian Fan, Fowler, Stephen, and Sont, Jacob K.

Published
2020
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46. Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank

Author

Mathioudakis, Alexander G., Custovic, Adnan, Deschildre, Antoine, Ducharme, Francine M., Kalayci, Omer, Murray, Clare, Garcia, Antonio Nieto, Phipatanakul, Wanda, Price, David, Sheikh, Aziz, Agache, Ioana, Bacharier, Leonard, Bonini, Matteo, Castro-Rodriguez, Jose A., De Carlo, Giuseppe, Craig, Timothy, Diamant, Zuzana, Feleszko, Wojciech, Ierodiakonou, Despo, Gern, James E., Grigg, Jonathan, Hedlin, Gunilla, Hossny, Elham M., Jartti, Tuomas, Kaplan, Alan, Lemanske, Robert F., Le Souef, Peter, Makela, Mika J., Matricardi, Paolo M., Miligkos, Michael, Morais-Almeida, Mário, Pite, Helena, Pitrez, Paulo M.C., Pohunek, Petr, Roberts, Graham, Sanchez-Garcia, Sylvia, Tsiligianni, Ioanna, Turner, Steve, Winders, Tonya A., Wong, Gary, Xepapadaki, Paraskevi, Zar, Heather J., and Papadopoulos, Nikolaos G.

Published
2020
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47. Telemedicine with special focus on allergic diseases and asthma—Status 2022: An EAACI position paper

Author

Smolinska, Sylwia, primary, Popescu, Florin‐Dan, additional, Izquierdo, Elena, additional, Antolín‐Amérigo, Darío, additional, Price, Oliver J., additional, Alvarez‐Perea, Alberto, additional, Eguíluz Gracia, Ibon, additional, Papadopoulos, Nikolaos G., additional, Pfaar, Oliver, additional, Fassio, Filippo, additional, Hoffmann‐Sommergruber, Karin, additional, Dramburg, Stephanie, additional, Agache, Ioana, additional, Jutel, Marek, additional, Brough, Helen A., additional, Fonseca, João A., additional, Angier, Elizabeth, additional, Boccabella, Cristina, additional, Bonini, Matteo, additional, Dunn Galvin, Audrey, additional, Gibson, Peter G., additional, Gawlik, Radoslaw, additional, Hannachi, Farah, additional, Kalayci, Ömer, additional, Klimek, Ludger, additional, Knibb, Rebecca, additional, Matricardi, Paolo, additional, and Chivato, Tomás, additional

Published
2023
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48. The Impact of Telemedicine during Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic and Future Perspectives: A Systematic Review

Author

Monteleone, Giorgio, Terzulli, Giovanni, Cefaloni, Francesca, Bonini, Matteo, Richeldi, Luca, Bonini, Matteo (ORCID:0000-0002-3042-0765), Richeldi, Luca (ORCID:0000-0001-8594-1448), Monteleone, Giorgio, Terzulli, Giovanni, Cefaloni, Francesca, Bonini, Matteo, Richeldi, Luca, Bonini, Matteo (ORCID:0000-0002-3042-0765), and Richeldi, Luca (ORCID:0000-0001-8594-1448)

Abstract

Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread worldwide since December 2019, causing the COVID-19 pandemic. Several measures have taken place in many countries to avoid further spread of the virus and to manage infected people according to disease severity. Notably, telemedicine (TM) was successfully used to manage less severe patients. Our aim was to assess the impact and the edges of using TM in home-isolated or hospitalized patients affected by SARS-CoV-2 infection and its further application. Methods: We performed a systematic review according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, focusing on randomized controlled trials (RCTs) published in English and available on PubMed database. Full texts were blindly reviewed and then assessed according to PICO model. Results: Our research identified a total of 1,959 records, of which 24 were potentially eligible through the articles full-text review. Six papers were included for data extraction and 18 articles were excluded: 10 articles were not RCTs and 8 articles did not involve SARS-CoV-2 patients. The TM application showed an improvement in psychological stress, mental disorders, and a significant reduction of general stress in patients affected by SARS-CoV-2 infection. The effectiveness of using TM in rehabilitative respiratory programs has been also reported. Furthermore, the benefits of TM application in tailored monitoring of vital parameters in home-isolated patients helped clinicians to early identify a deterioration of clinical conditions. Conclusion: The use of TM during COVID-19 pandemic represented a novel, intriguing, versatile, and useful tool to support clinical practice. This evidence suggests considering TM in a wider range of clinical applications.

Published
2023

49. Mobile Technology in Allergic Rhinitis: Evolution in Management or Revolution in Health and Care?

Author

Bousquet, Jean, Ansotegui, Ignacio J., Anto, Josep M., Arnavielhe, Sylvie, Bachert, Claus, Basagaña, Xavier, Bédard, Annabelle, Bedbrook, Anna, Bonini, Matteo, Bosnic-Anticevich, Sinthia, Braido, Fulvio, Cardona, Vicky, Czarlewski, Wienczyslawa, Cruz, Alvaro A., Demoly, Pascal, De Vries, Govert, Dramburg, Stephanie, Mathieu-Dupas, Eve, Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Haahtela, Tari, Hellings, Peter W., Illario, Maddalena, Ivancevich, Juan Carlos, Jormanainen, Vesa, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Laune, Daniel, Larenas-Linnemann, Désirée, Lourenço, Olga, Onorato, Gabrielle L., Matricardi, Paolo M., Melén, Erik, Mullol, Joaquim, Papadopoulos, Nikos G., Pfaar, Oliver, Pham-Thi, Nhân, Sheikh, Aziz, Tan, Rachel, To, Teresa, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tripodi, Salvadore, Wallace, Dana, Valiulis, Arunas, van Eerd, Michiel, Ventura, Maria Teresa, Yorgancioglu, Arzu, and Zuberbier, Torsten

Published
2019
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