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1. Severe postoperative morbidity after left colectomy for sigmoid diverticulitis without splenic flexure mobilization. Results of a multicenter cohort study with propensity score analysis

Author

Barraud, Alexis, Sabbagh, Charles, Beyer-Berjot, Laura, Ouaissi, Mehdi, Zerbib, Philippe, Bridoux, Valérie, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, Godet, Camille, Eid, Yassine, Duchalais, Emilie, Lakkis, Zaher, Cotte, Eddy, Laforest, Anaïs, Defourneaux, Véronique, Maggiori, Léon, Rebibo, Lionel, Christou, Niki, Talal, Ali, Mege, Diane, Bonnamy, Cécile, Germain, Adeline, Mauvais, François, Tresallet, Christophe, Roudie, Jean, Laurent, Alexis, Trilling, Bertrand, Bertrand, Martin, Massalou, Damien, Romain, Benoit, Tranchart, Hadrien, Pellegrin, Alexandra, Briant, Anais R., Parienti, Jean Jacques, and Alves, Arnaud

Published
2024
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2. Risk factors for emergency surgery for diverticulitis: A retrospective multicentric French study at 41 hospitals

Author

Jeanne, Dembinski, Gillet, Julien, Hamy, Antoine, Lahmidi, Amine, Sebbagh, Mohamed, Bres, Antoine, Girard, Nicolas, Desjouis, Aurélie, Ainseba, Nadjib, Epailly, Julien, Huysman, Fabienne, Dezeustre, Maud, Doussot, Alexandre, Turco, Célia, Bourrhis, Diane, Godet, Camille, Finocchi, Morgane, Marion, Yoan, Lebreton, Gil, Benard, Flavie, Pineau, Elodie, Bouvier, Véronique, Ortega-Deballon, Pablo, Moreno-Lopez, Nathan, Rat, Patrick, Makar, Bassem, Fara, Paola, Pompilio, Marc, Hertault, Hugo, Guezennec, Corentin, Saida, Habchi, Brinza, Alexandre, Plard, Laurent, Ailhaud, Antoine, Gutierrez, Léa, Venchiarutti, Vincent, Faucheron, Jean-Luc, Morin, Bertrand, Pech de la Clause, Bertrand, Voitellier, Eglantine, Gagnat, Guillaume, Noiret, Barbara, Laroye, Constance, Piessen, Guillaume, Lécolle, Katia, Robert, Jean, Nzamushelepanmabla, Engel, Perrine, Mathonnet, Muriel, Rodriguez, Cyprien, Makki, Ammar, Couchard, Anne-Cécile, Duramé, François, Marceau, Cécile, Paquet, Jean-Christophe, Kepenekian, Vahan, Passot, Guillaume, Glehen ; Ninon Wallach, Olivier, Mohkam, Kayvan, Blanc, Marie-Caroline, Berdah, Stéphane, Aubert, Mathilde, Ayav, Ahmet, Chanty, Hervé, Didier, Alexandre, Vigneron, Estelle, Périard, Noémie, Thaumoux, Marie, Grenouilloux, Océane, Fall, Seila, Thomareis, Sophoclis, Marsollier, Chloé, Prud’homme, Michel, Antonopulos, Christos, Msika, Simon, Monsinjon, Marie, Giacca, Massimo, Cazelles, Antoine, Karoui, Mehdi, Malerba, Valentina, Dagher, Ibrahim, de Angelis, Nicola, Brunetti, Francesco, Ahmed, Omar, Ferraz, Jean-Marc, Ramjaun, Yassir, Denet, Christine, Fuchs, Basile, Pietrasz, Daniel, Raimbert, Pénélope, Benedetti, Juliette, Coton, Chloé, Corte, Hélène, Medrignac, Aude, Chavrier, Daphné, Girard, Robin, Berthelot, Julia, Monge, Matthieu, Papet, Eloïse, Pinson, Jean, Dolbeau, Elise, Tuech, Jean-Jacques, Chautard, Julien, Boullier, Mathilde, Goujard, François, Perrot, Laurent, Loge, Ludovic, Petiot, Jean-Michel, Manfredelli, Simone, Charleux-Muller, Diane, Sauvinet, Guillaume, Bertin, Jean-Baptiste, Vincent, Louis, Simeu, Blandine, Delhorme, Jean-Baptiste, Brigand, Cécile, Rohr, Serge, Bouchet, Manon, Duffas, Jean-Pierre, Ghouti, Laurent, Philis, Antoine, Portier, Guillaume, Karam, Elias, Michot, Nicolas, Artus, Alice, Mauny, Emilien, Bourbao-Tournois, Céline, Barbin, Hugo, Thiery, Julien, Sabbagh, Charles, Beyer-Berjot, Laura, Ouaissi, Mehdi, Zerbib, Philippe, Valérie, Bridoux, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, Eid, Yassine, Duchalais, Emilie, Lakkis, Zaher, Cotte, Eddy, Laforest, Anaïs, Desfourneaux-Denis, Véronique, Maggiori, Léon, Rebibo, Lionel, Niki, Christou, Talal, Ali, Mege, Diane, Bonnamy, Cécile, Germain, Adeline, Mauvais, François, Tresallet, Christophe, Roudie, Jean, Laurent, Alexis, Trilling, Bertrand, Bertrand, Martin, Massalou, Damien, Romain, Benoit, Tranchart, Hadrien, Pellegrin, Alexandra, Dejardin, Olivier, and Alves, Arnaud

Published
2024
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3. Impact of the first wave of COVID-19 epidemy on the surgical management of sigmoid diverticular disease in France: National French retrospective study

Author

Gil, Camille, Beyer-Bergeot, Laura, Sabbagh, Charles, Zerbib, Philippe, Bridoux, Valérie, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bodgan, Godet, Camille, Eid, Yassine, Duchalais, Emilie, Lakkis, Zaher, Cotte, Eddy, Laforest, Anais, Defourneaux, Véronique, Maggiori, Léon, Rebibo, Lionel, Christou, Niki, Talal, Ali, Mege, Diane, Bonnamy, Cécile, Germain, Adeline, Mauvais, François, Tresallet, Christophe, Roudie, Jean, Laurent, Alexis, Trilling, Bertrand, Bertrand, Martin, Massalou, Damien, Romain, Benoit, Tranchart, Hadrien, Giger, Urs, Alves, Arnaud, and Ouaissi, Mehdi

Published
2023
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4. Influence of Socioeconomic Deprivation on Surgical Outcomes for Patients With Sigmoid Diverticulitis in France: A Multicenter Retrospective Study.

Author

Alves, Arnaud, Sabbagh, Charles, Ouaissi, Mehdi, Zerbib, Philippe, Bridoux, Valérie, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, Godet, Camille, and Eid, Yassine

Abstract

Objectives: To evaluate the relationship between socioeconomic deprivation and postoperative outcomes in patients who underwent colonic resection for sigmoid diverticulitis (SD). Background: The potential impact of socioeconomic inequalities on the management of SD has been scarcely studied in the literature. Considering other gastrointestinal pathologies for which lesser access to optimal treatment and poorer survival have been shown, we hypothesize that deprivation could be associated with outcomes for SD. Methods: This multicenter retrospective study was conducted at 41 French hospitals between January 1, 2010, and August 31, 2021. The main outcome was the occurrence of severe postoperative complications on postoperative day 90, according to the Clavien- Dindo scale (≥3). The European Deprivation Index was used to approximate deprivation for each patient. Multiple imputations by a chained equation were performed to consider the influence of missing data on the results. Results: Twenty percent of the 6415 patients operated on had severe postoperative complications at 90 days. In the multivariate regression analysis, increasing age, male sex, American Society of Anesthesiologists score ≥3, conversion to laparotomy or upfront open approach, surgical procedures, and perioperative transfusion were independent risk factors for severe postoperative complications. After adjusting for age, sex, body mass index, American Society of Anesthesiologists score, emergent setting, blood transfusion, indications for surgery, surgical approach, and procedures, the probability of severe postoperative complications increased with socioeconomic deprivation (P=0.026) by day 90. Conclusions: This study highlights the potential influence of socioeconomic deprivation on the surgical outcomes of SD. Socioeconomic deprivation should be considered as a risk factor for severe postoperative complications during the preoperative assessment of the patient's medical conditions. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Stenosis of the colorectal anastomosis after surgery for diverticulitis: A national retrospective cohort study.

Author

Hamel, Jean‐Francois, Alves, Arnaud, Beyer‐Bergot, Laura, Zerbib, Philippe, Bridoux, Valérie, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean‐Yves, Badic, Bodgan, Godet, Camille, Eid, Yassine, and Duchalais, Emilie

Subjects
DIVERTICULITIS, STENOSIS, SURGICAL anastomosis, SURGICAL emergencies, MESENTERIC artery, ILEOSTOMY
Abstract

Aim: The aim of this work was to investigate the association between early postoperative anastomotic leakage or pelvic abscess (AL/PA) and symptomatic anastomotic stenosis (SAS) in patients after surgery for left colonic diverticulitis. Method: This is a retrospective study based on a national cohort of diverticulitis surgery patients carried out by the Association Française de Chirurgie. The assessment was performed using path analyses. The database included 7053 patients operated on for colonic diverticulitis, with surgery performed electively or in an emergency, by open access or laparoscopically. Patients were excluded from the study analysis where there was (i) right‐sided diverticulitis (the initial database included all consecutive patients operated on for colonic diverticulitis), (ii) no anastomosis was performed during the first procedure or (iii) missing information about stenosis, postoperative abscess or anastomotic leakage. Results: Of the 4441 patients who were included in the final analysis, AL/PA occurred in 327 (4.6%) and SAS occurred in 82 (1.8%). AL/PA was a significant independent factor associated with a risk for occurrence of SAS (OR = 3.41, 95% CI = 1.75–6.66), as was the case for diverting stoma for ≥100 days (OR = 2.77, 95% CI = 1.32–5.82), while central vessel ligation proximal to the inferior mesenteric artery was associated with a reduced risk (OR = 0.41; 95% CI = 0.19–0.88). Diverting stoma created for <100 days or ≥100 days was also a factor associated with a risk for AL/PA (OR = 3.08, 95% CI = 2–4.75 and OR = 12.95, 95% CI = 9.11–18.50). Interestingly, no significant association between radiological drainage or surgical management of AL/PA and SAS could be highlighted. Conclusion: AL/PA was an independent factor associated with the risk for SAS. The treatment of AL/PA was not associated with the occurrence of anastomotic stenosis. Diverting stoma was associated with an increased risk of both AL/PA and SAS, especially if it was left for ≥100 days. Physicians must be aware of this information in order to decide on the best course of action when creating a stoma during elective or emergency surgery. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Risk factors for emergency surgery for diverticulitis: A retrospective multicentric French study at 41 hospitals.

Author

Godet, Camille, Sabbagh, Charles, Beyer-Berjot, Laura, Ouaissi, Mehdi, Zerbib, Philippe, Valérie, Bridoux, Manceau, Gilles, Panis, Yves, Buscail, Etienne, Venara, Aurélien, Khaoudy, Iman, Gaillard, Martin, Viennet, Manon, Thobie, Alexandre, Menahem, Benjamin, Eveno, Clarisse, Bonnel, Catherine, Mabrut, Jean-Yves, Badic, Bogdan, and Chautard, Julien

Abstract

The observed increase in the incidence of complicated diverticulitis may lead to the performance of more emergency surgeries. This study aimed to assess the rate and risk factors of emergency surgery for sigmoid diverticulitis. The primary outcomes were the rate of emergency surgery for sigmoid diverticulitis and its associated risk factors. The urgent or elective nature of the surgical intervention was provided by the surgeon and in accordance with the indication for surgical treatment. A mixed logistic regression with a random intercept after multiple imputations by the chained equation was performed to consider the influence of missing data on the results. Between 2010 and 2021, 6,867 patients underwent surgery for sigmoid diverticulitis in the participating centers, of which one-third (n = 2317) were emergency cases. In multivariate regression analysis with multiple imputation by chained equation, increasing age, body mass index <18.5 kg/m2, neurologic and pulmonary comorbidities, use of anticoagulant drugs, immunocompromised status, and first attack of sigmoid diverticulitis were independent risk factors for emergency surgery. The likelihood of emergency surgery was significantly more frequent after national guidelines, which were implemented in 2017, only in patients with a history of sigmoid diverticulitis attacks. The present study highlights a high rate (33%) of emergency surgery for sigmoid diverticulitis in France, which was significantly associated with patient features and the first attack of diverticulitis. [ABSTRACT FROM AUTHOR]

Published
2024
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12. A Randomized Study of Bolus Fluorouracil Plus Folinic Acid Versus 21-Day Fluorouracil Infusion Alone or in Association with Cyclophosphamide and Mitomycin C in Advanced Colorectal Carcinoma

Author

Caudry, Michel, primary, Bonnel, Catherine, additional, Floquet, Anne, additional, Marsault, Claude, additional, Quétin, Philippe, additional, Pujol, José, additional, Maton, Olivier, additional, Dujols, Jean-Pierre, additional, Caudry, Yolande, additional, Skawinski, Philippe, additional, Carenco, Jacques, additional, Mokhtari, Fatma, additional, Célérier, Denis, additional, Quinton, Andre, additional, Demeaux, Hélène, additional, and Maire, Jean-Philippe, additional

Published
1995
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