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7. Improved diagnostic performance of insertable cardiac monitors by an artificial intelligence-based algorithm.

Author

Crespin, Eliot, Rosier, Arnaud, Ibnouhsein, Issam, Gozlan, Alexandre, Lazarus, Arnaud, Laurent, Gabriel, Menet, Aymeric, Bonnet, Jean-Luc, and Varma, Niraj

Abstract

Aims The increasing use of insertable cardiac monitors (ICM) produces a high rate of false positive (FP) diagnoses. Their verification results in a high workload for caregivers. We evaluated the performance of an artificial intelligence (AI)-based ILR-ECG Analyzer™ (ILR-ECG-A). This machine-learning algorithm reclassifies ICM-transmitted events to minimize the rate of FP diagnoses, while preserving device sensitivity. Methods and results We selected 546 recipients of ICM followed by the Implicity™ monitoring platform. To avoid clusterization, a single episode per ICM abnormal diagnosis (e.g. asystole, bradycardia, atrial tachycardia (AT)/atrial fibrillation (AF), ventricular tachycardia, artefact) was selected per patient, and analyzed by the ILR-ECG-A, applying the same diagnoses as the ICM. All episodes were reviewed by an adjudication committee (AC) and the results were compared. Among 879 episodes classified as abnormal by the ICM, 80 (9.1%) were adjudicated as 'Artefacts', 283 (32.2%) as FP, and 516 (58.7%) as 'abnormal' by the AC. The algorithm reclassified 215 of the 283 FP as normal (76.0%), and confirmed 509 of the 516 episodes as abnormal (98.6%). Seven undiagnosed false negatives were adjudicated as AT or non-specific abnormality. The overall diagnostic specificity was 76.0% and the sensitivity was 98.6%. Conclusion The new AI-based ILR-ECG-A lowered the rate of FP ICM diagnoses significantly while retaining a > 98% sensitivity. This will likely alleviate considerably the clinical burden represented by the review of ICM events. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Sensitivity Analysis of Vagus Nerve Stimulation Parameters on Acute Cardiac Autonomic Responses: Chronotropic, Inotropic and Dromotropic Effects

Author

Ojeda, David, primary, Le Rolle, Virginie, additional, Romero-Ugalde, Hector M., additional, Gallet, Clément, additional, Bonnet, Jean-Luc, additional, Henry, Christine, additional, Bel, Alain, additional, Mabo, Philippe, additional, Carrault, Guy, additional, and Hernández, Alfredo I., additional

Published
2016
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16. Vagus nerve stimulation: state of the art of stimulation and recording strategies to address autonomic function neuromodulation

Author

Guiraud, David, primary, Andreu, David, additional, Bonnet, Stéphane, additional, Carrault, Guy, additional, Couderc, Pascal, additional, Hagège, Albert, additional, Henry, Christine, additional, Hernandez, Alfredo, additional, Karam, Nicole, additional, Le Rolle, Virginie, additional, Mabo, Philippe, additional, Maciejasz, Paweł, additional, Malbert, Charles-Henri, additional, Marijon, Eloi, additional, Maubert, Sandrine, additional, Picq, Chloé, additional, Rossel, Olivier, additional, and Bonnet, Jean-Luc, additional

Published
2016
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18. Characteristics of the right cervical vagal activity during baseline and Valsalva-like manoeuvre

Author

Gallet, Clement, primary, Bonnet, Stephane, additional, Le Rolle, Virgine, additional, Laporte, Laure, additional, Bonnet, Jean-Luc, additional, Karam, Nicole, additional, Hagege, Albert, additional, Malbert, Charles-Henry, additional, Mabo, Philippe, additional, Maubert, Sandrine, additional, Hernandez, Alfredo I., additional, and Carrault, Guy, additional

Published
2015
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19. Model-based design of control modules for neuromodulation devices

Author

Romero Ugalde, Hector M, primary, Ojeda, David, additional, Le Rolle, Virginie, additional, Rossel, Olivier, additional, Bonnet, Jean-Luc, additional, Karam, Nicole, additional, Hagege, Albert, additional, Mabo, Philippe, additional, Carrault, Guy, additional, and Hernandez, Alfredo I., additional

Published
2015
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21. Integration of the End Cap TEC+ of the CMS Silicon Strip Tracker

Author

Adler, Volker, Adolphi, Roman, Ageron, Michel, Agram, Jean-Laurent, Atz, Bernd, Barvich, Tobias, Baulieu, Guillaume, Beaumont, Willem, Beissel, Franz, Bergauer, Thomas, Berst, Jean-Daniel, Blüm, Peter, Bock, E, Bogelsbacher, F, de Boer, Wim, Bonnet, Jean-Luc, Bonnevaux, Alain, Boudoul, Gaelle, Bouhali, Othmane, Braunschweig, Wolfgang, Bremer, R, Brom, Jean-Marie, Butz, Erik, Chabanat, Eric, Chabert, Eric Christian, Clerbaux, Barbara, Contardo, Didier, De Callatay, Bernard, Dehm, Philip, Delaere, Christophe, Della Negra, Rodolphe, Dewulf, Jean-Paul, D'Hondt, Jorgen, Didierjean, Francois, Dierlamm, Alexander, Dirkes, Guido, Dragicevic, Marko, Drouhin, Frédéric, Ernenwein, Jean-Pierre, Esser, Hans, Estre, Nicolas, Fahrer, Manuel, Feld, Lutz, Fernández, J, Florins, Benoit, Flossdorf, Alexander, Flucke, Gero, Flügge, Günter, Fontaine, Jean-Charles, Freudenreich, Klaus, Frey, Martin, Friedl, Markus, Furgeri, Alexander, Giraud, Noël, Goerlach, Ulrich, Goorens, Robert, Graehling, Philippe, Grégoire, Ghislain, Gregoriev, E, Gross, Laurent, Hansel, S, Haroutunian, Roger, Hartmann, Frank, Heier, Stefan, Hermanns, Thomas, Heydhausen, Dirk, Heyninck, Jan, Hosselet, J, Hrubec, Josef, Jahn, Dieter, Juillot, Pierre, Kaminski, Jochen, Karpinski, Waclaw, Kaussen, Gordon, Keutgen, Thomas, Klanner, Robert, Klein, Katja, König, Stefan, Kosbow, M, Krammer, Manfred, Ledermann, Bernhard, Lemaître, Vincent, De Lentdecker, Gilles, Linn, Alexander, Lounis, Abdenour, Lübelsmeyer, Klaus, Lumb, Nicholas, Maazouzi, Chaker, Mahmoud, Tariq, Michotte, Daniel, Militaru, Otilia, Mirabito, Laurent, Müller, Thomas, Neukermans, Lionel, Ollivetto, C, Olzem, Jan, Ostapchuk, Andrey, Pandoulas, Demetrios, Pein, Uwe, Pernicka, Manfred, Perriès, Stephane, Piaseki, C, Pierschel, Gerhard, Piotrzkowski, Krzysztof, Poettgens, Michael, Pooth, Oliver, Rouby, Xavier, Sabellek, Andreas, Schael, Stefan, Schirm, Norbert, Schleper, Peter, Schmitz, Stefan Antonius, Schultz von Dratzig, Arndt, Siedling, Rolf, Simonis, Hans-Jürgen, Stahl, Achim, Steck, Pia, Steinbruck, G, Stoye, Markus, Strub, Roger, Tavernier, Stefaan, Teyssier, Daniel, Theel, Andreas, Trocmé, Benjamin, Udo, Fred, Van der Donckt, M, Van der Velde, C, Van Hove, Pierre, Vanlaer, Pascal, Van Lancker, Luc, Van Staa, Rolf, Vanzetto, Sylvain, Weber, Markus, Weiler, Thomas, Weseler, Siegfried, Wickens, John, Wittmer, Bruno, Wlochal, Michael, De Wolf, Eddi A, Zhukov, Valery, and Zoeller, Marc Henning

Subjects
Detectors and Experimental Techniques
Abstract

The silicon strip tracker of the CMS experiment has been completed and inserted into the CMS detector in late 2007. The largest sub-system of the tracker is its end cap system, comprising two large end caps (TEC) each containing 3200 silicon strip modules. To ease construction, the end caps feature a modular design: groups of about 20 silicon modules are placed on sub-assemblies called petals and these self-contained elements are then mounted into the TEC support structures. Each end cap consists of 144 petals, and the insertion of these petals into the end cap structure is referred to as TEC integration. The two end caps were integrated independently in Aachen (TEC+) and at CERN (TEC--). This note deals with the integration of TEC+, describing procedures for end cap integration and for quality control during testing of integrated sections of the end cap and presenting results from the testing.

Published
2009

22. Reception Test of Petals for the End Cap TEC+ of the CMS Silicon Strip Tracker

Author

Bremer, R, Feld, Lutz, Klein, Katja, Schmitz, Stefan Antonius, Adler, Volker, Adolphi, Roman, Ageron, Michel, Agram, Jean-Laurent, Atz, Bernd, Barvich, Tobias, Baulieu, Guillaume, Beaumont, Willem, Beissel, Franz, Bergauer, Thomas, Berst, Jean-Daniel, Blüm, Peter, Bock, E, Bogelsbacher, F, de Boer, Wim, Bonnet, Jean-Luc, Bonnevaux, Alain, Boudoul, Gaelle, Bouhali, Othmane, Braunschweig, Wolfgang, Brom, Jean-Marie, Butz, Erik, Chabanat, Eric, Chabert, Eric Christian, Clerbaux, Barbara, Contardo, Didier, De Callatay, Bernard, Dehm, Philip, Delaere, Christophe, Della Negra, Rodolphe, Dewulf, Jean-Paul, D'Hondt, Jorgen, Didierjean, Francois, Dierlamm, Alexander, Dirkes, Guido, Dragicevic, Marko, Drouhin, Frédéric, Ernenwein, Jean-Pierre, Esser, Hans, Estre, Nicolas, Fahrer, Manuel, Fernández, J, Florins, Benoit, Flossdorf, Alexander, Flucke, Gero, Flügge, Günter, Fontaine, Jean-Charles, Freudenreich, Klaus, Frey, Martin, Friedl, Markus, Furgeri, Alexander, Giraud, Noël, Goerlach, Ulrich, Goorens, Robert, Graehling, Philippe, Grégoire, Ghislain, Gregoriev, E, Gross, Laurent, Hansel, S, Haroutunian, Roger, Hartmann, Frank, Heier, Stefan, Hermanns, Thomas, Heydhausen, Dirk, Heyninck, Jan, Hosselet, J, Hrubec, Josef, Jahn, Dieter, Juillot, Pierre, Kaminski, Jochen, Karpinski, Waclaw, Kaussen, Gordon, Keutgen, Thomas, Klanner, Robert, König, Stefan, Kosbow, M, Krammer, Manfred, Ledermann, Bernhard, Lemaître, Vincent, De Lentdecker, Gilles, Linn, Alexander, Lounis, Abdenour, Lübelsmeyer, Klaus, Lumb, Nicholas, Maazouzi, Chaker, Mahmoud, Tariq, Michotte, Daniel, Militaru, Otilia, Mirabito, Laurent, Müller, Thomas, Neukermans, Lionel, Ollivetto, C, Olzem, Jan, Ostapchuk, Andrey, Pandoulas, Demetrios, Pein, Uwe, Pernicka, Manfred, Perriès, Stephane, Piaseki, C, Pierschel, Gerhard, Piotrzkowski, Krzysztof, Poettgens, Michael, Pooth, Oliver, Rouby, Xavier, Sabellek, Andreas, Schael, Stefan, Schirm, Norbert, Schleper, Peter, Schultz von Dratzig, Arndt, Siedling, Rolf, Simonis, Hans-Jürgen, Stahl, Achim, Steck, Pia, Steinbruck, G, Stoye, Markus, Strub, Roger, Tavernier, Stefaan, Teyssier, Daniel, Theel, Andreas, Trocmé, Benjamin, Udo, Fred, Van der Donckt, M, Van der Velde, C, Van Hove, Pierre, Vanlaer, Pascal, Van Lancker, Luc, Van Staa, Rolf, Vanzetto, Sylvain, Weber, Markus, Weiler, Thomas, Weseler, Siegfried, Wickens, John, Wittmer, Bruno, Wlochal, Michael, De Wolf, Eddi A, Zhukov, Valery, and Zoeller, Marc Henning

Subjects
Detectors and Experimental Techniques
Abstract

The silicon strip tracker of the CMS experiment has been completed and was inserted into the CMS detector in late 2007. The largest sub system of the tracker are its end caps, comprising two large end caps (TEC) each containing 3200 silicon strip modules. To ease construction, the end caps feature a modular design: groups of about 20 silicon modules are placed on sub-assemblies called petals and these self-contained elements are then mounted onto the TEC support structures. Each end cap consists of 144 such petals, which were built and fully qualified by several institutes across Europe. From

Published
2009

23. Track Reconstruction with Cosmic Ray Data at the Tracker Integration Facility

Author

Adam, Wolfgang, Bergauer, Thomas, Dragicevic, Marko, Friedl, Markus, Fruhwirth, R, Hansel, S, Hrubec, Josef, Krammer, Manfred, Oberegger, Margit, Pernicka, Manfred, Schmid, Siegfried, Stark, Roland, Steininger, Helmut, Uhl, Dieter, Waltenberger, Wolfgang, Widl, Edmund, Van Mechelen, Pierre, Cardaci, Marco, Beaumont, Willem, de Langhe, Eric, de Wolf, Eddi A, Delmeire, Evelyne, Hashemi, Majid, Bouhali, Othmane, Charaf, Otman, Clerbaux, Barbara, Elgammal, J.-P. Dewulf. S, Hammad, Gregory Habib, de Lentdecker, Gilles, Marage, Pierre Edouard, Vander Velde, Catherine, Vanlaer, Pascal, Wickens, John, Adler, Volker, Devroede, Olivier, De Weirdt, Stijn, D'Hondt, Jorgen, Goorens, Robert, Heyninck, Jan, Maes, Joris, Mozer, Matthias Ulrich, Tavernier, Stefaan, Van Lancker, Luc, Van Mulders, Petra, Villella, Ilaria, Wastiels, C, Bonnet, Jean-Luc, Bruno, Giacomo, De Callatay, Bernard, Florins, Benoit, Giammanco, Andrea, Gregoire, Ghislain, Keutgen, Thomas, Kcira, Dorian, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Quertermont, L, Roberfroid, Vincent, Rouby, Xavier, Teyssier, Daniel, Daubie, Evelyne, Anttila, Erkki, Czellar, Sandor, Engstrom, Pauli, Harkonen, J, Karimaki, V, Kostesmaa, J, Kuronen, Auli, Lampen, Tapio, Linden, Tomas, Luukka, Panja-Riina, Maenpaa, T, Michal, Sebastien, Tuominen, Eija, Tuominiemi, Jorma, Ageron, Michel, Baulieu, Guillaume, Bonnevaux, Alain, Boudoul, Gaelle, Chabanat, Eric, Chabert, Eric Christian, Chierici, Roberto, Contardo, Didier, Della Negra, Rodolphe, Dupasquier, Thierry, Gelin, Georges, Giraud, Noël, Guillot, Gérard, Estre, Nicolas, Haroutunian, Roger, Lumb, Nicholas, Perries, Stephane, Schirra, Florent, Trocme, Benjamin, Vanzetto, Sylvain, Agram, Jean-Laurent, Blaes, Reiner, Drouhin, Frédéric, Ernenwein, Jean-Pierre, Fontaine, Jean-Charles, Berst, Jean-Daniel, Brom, Jean-Marie, Didierjean, Francois, Goerlach, Ulrich, Graehling, Philippe, Gross, Laurent, Hosselet, J, Juillot, Pierre, Lounis, Abdenour, Maazouzi, Chaker, Olivetto, Christian, Strub, Roger, Van Hove, Pierre, Anagnostou, Georgios, Brauer, Richard, Esser, Hans, Feld, Lutz, Karpinski, Waclaw, Klein, Katja, Kukulies, Christoph, Olzem, Jan, Ostapchuk, Andrey, Pandoulas, Demetrios, Pierschel, Gerhard, Raupach, Frank, Schael, Stefan, Schwering, Georg, Sprenger, Daniel, Thomas, Maarten, Weber, Markus, Wittmer, Bruno, Wlochal, Michael, Beissel, Franz, Bock, E, Flugge, G, Gillissen, C, Hermanns, Thomas, Heydhausen, Dirk, Jahn, Dieter, Kaussen, Gordon, Linn, Alexander, Perchalla, Lars, Poettgens, Michael, Pooth, Oliver, Stahl, Achim, Zoeller, Marc Henning, Buhmann, Peter, Butz, Erik, Flucke, Gero, Hamdorf, Richard Helmut, Hauk, Johannes, Klanner, Robert, Pein, Uwe, Schleper, Peter, Steinbruck, G, Blum, P, De Boer, Wim, Dierlamm, Alexander, Dirkes, Guido, Fahrer, Manuel, Frey, Martin, Furgeri, Alexander, Hartmann, Frank, Heier, Stefan, Hoffmann, Karl-Heinz, Kaminski, Jochen, Ledermann, Bernhard, Liamsuwan, Thiansin, Muller, S, Muller, Th, Schilling, Frank-Peter, Simonis, Hans-Jürgen, Steck, Pia, Zhukov, Valery, Cariola, P, De Robertis, Giuseppe, Ferorelli, Raffaele, Fiore, Luigi, Preda, M, Sala, Giuliano, Silvestris, Lucia, Tempesta, Paolo, Zito, Giuseppe, Creanza, Donato, De Filippis, Nicola, De Palma, Mauro, Giordano, Domenico, Maggi, Giorgio, Manna, Norman, My, Salvatore, Selvaggi, Giovanna, Albergo, Sebastiano, Chiorboli, Massimiliano, Costa, Salvatore, Galanti, Mario, Giudice, Nunzio, Guardone, Nunzio, Noto, Francesco, Potenza, Renato, Saizu, Mirela Angela, Sparti, V, Sutera, Concetta, Tricomi, Alessia, Tuve, Cristina, Brianzi, Mirko, Civinini, Carlo, Maletta, Fernando, Manolescu, Florentina, Meschini, Marco, Paoletti, Simone, Sguazzoni, Giacomo, Broccolo, B, Ciulli, Vitaliano, Focardi, R. D'Alessandro. E, Frosali, Simone, Genta, Chiara, Landi, Gregorio, Lenzi, Piergiulio, Macchiolo, Anna, Magini, Nicolo, Parrini, Giuliano, Scarlini, Enrico, Cerati, Giuseppe Benedetto, Azzi, Patrizia, Bacchetta, Nicola, Candelori, Andrea, Dorigo, Tommaso, Kaminsky, A, Karaevski, S, Khomenkov, Volodymyr, Reznikov, Sergey, Tessaro, Mario, Bisello, Dario, De Mattia, Marco, Giubilato, Piero, Loreti, Maurizio, Mattiazzo, Serena, Nigro, Massimo, Paccagnella, Alessandro, Pantano, Devis, Pozzobon, Nicola, Tosi, Mia, Bilei, Gian Mario, Checcucci, Bruno, Fano, Livio, Servoli, Leonello, Ambroglini, Filippo, Babucci, Ezio, Benedetti, Daniele, Biasini, Maurizio, Caponeri, Benedetta, Covarelli, Roberto, Giorgi, Marco, Lariccia, Paolo, Mantovani, Giancarlo, Marcantonini, Marta, Postolache, Vasile, Santocchia, Attilio, Spiga, Daniele, Bagliesi, Giuseppe, Balestri, Gabriele, Berretta, Luca, Bianucci, S, Boccali, Tommaso, Bosi, Filippo, Bracci, Fabrizio, Castaldi, Rino, Ceccanti, Marco, Cecchi, Roberto, Cerri, Claudio, Cucoanes, Andi Sebastian, Dell'Orso, Roberto, Dobur, Didar, Dutta, Suchandra, Giassi, Alessandro, Giusti, Simone, Kartashov, Dmitry, Kraan, Aafke, Lomtadze, Teimuraz, Lungu, George-Adrian, Magazzu, Guido, Mammini, Paolo, Mariani, Filippo, Martinelli, Giovanni, Moggi, Andrea, Palla, Fabrizio, Palmonari, Francesco, Petragnani, Giulio, Profeti, Alessandro, Raffaelli, Fabrizio, Rizzi, Domenico, Sanguinetti, Giulio, Sarkar, Subir, Sentenac, Daniel, Serban, Alin Titus, Slav, Adrian, Soldani, A, Spagnolo, Paolo, Tenchini, Roberto, Tolaini, Sergio, Venturi, Andrea, Verdini, Piero Giorgio, Vos, Marcel, Zaccarelli, Luciano, Avanzini, Carlo, Basti, Andrea, Benucci, Leonardo, Bocci, Andrea, Cazzola, Ugo, Fiori, Francesco, Linari, Stefano, Massa, Maurizio, Messineo, Alberto, Segneri, Gabriele, Tonelli, Guido, Azzurri, Paolo, Bernardini, Jacopo, Borrello, Laura, Calzolari, Federico, Foa, Lorenzo, Gennai, Simone, Ligabue, Franco, Petrucciani, Giovanni, Rizzi, Andrea, Yang, Zong-Chang, Benotto, Franco, Demaria, Natale, Dumitrache, Floarea, Farano, R, Borgia, Maria Assunta, Castello, Roberto, Costa, Marco, Migliore, Ernesto, Romero, Alessandra, Abbaneo, Duccio, Abbas, M, Ahmed, Ijaz, Akhtar, I, Albert, Eric, Bloch, Christoph, Breuker, Horst, Butt, Shahid Aleem, Buchmuller, Oliver, Cattai, Ariella, Delaere, Christophe, Delattre, Michel, Edera, Laura Maria, Eppard, Michael, Gateau, Maryline, Gill, Karl, Giolo-Nicollerat, Anne-Sylvie, Grabit, Robert, Honma, Alan, Huhtinen, Mika, Kloukinas, Kostas, Kortesmaa, Jarmo, Kottelat, Luc-Joseph, Leonardo, Nuno, Ljuslin, Christer, Mannelli, Marcello, Masetti, Lorenzo, Marchioro, Alessandro, Mersi, Stefano, Mirabito, Laurent, Muffat-Joly, Jeannine, Onnela, Antti, Paillard, Christian, Pal, Imre, Pernot, Jean-Francois, Petagna, Paolo, Petit, Patrick, Piccut, C, Pioppi, Michele, Postema, Hans, Ranieri, Riccardo, Ricci, Daniel, Rolandi, Gigi, Ronga, Frederic Jean, Sigaud, Christophe, Syed, A, Siegrist, Patrice, Tropea, Paola, Troska, Jan, Tsirou, Andromachi, Vander Donckt, Muriel, Vasey, François, Alagoz, Enver, Amsler, Claude, Chiochia, Vincenzo, Regenfus, Christian, Robmann, Peter, Rochet, Jacky, Rommerskirchen, Tanja, Schmidt, Alexander, Steiner, Stefan, Wilke, Lotte, Church, Ivan, Cole, Joanne, Coughlan, John A, Gay, Arnaud, Taghavi, S, Tomalin, Ian R, Bainbridge, Robert, Cripps, Nicholas, Fulcher, Jonathan, Hall, Geoffrey, Noy, Matthew, Pesaresi, Mark, Radicci, Valeria, Raymond, David Mark, Sharp, Peter, Stoye, Markus, Wingham, Matthew, Zorba, Osman, Goitom, Israel, Hobson, Peter R, Reid, Ivan, Teodorescu, Liliana, Hanson, Gail, Jeng, Geng-Yuan, Liu, Haidong, Pasztor, Gabriella, Satpathy, Asish, Stringer, Robert, Mangano, Boris, Affolder, K, Affolder, T, Allen, Andrea, Barge, Derek, Burke, Samuel, Callahan, D, Campagnari, Claudio, Crook, A, D'Alfonso, Mariarosaria, Dietch, J, Garberson, Jeffrey, Hale, David, Incandela, H, Incandela, Joe, Jaditz, Stephen, Kalavase, Puneeth, Kreyer, Steven Lawrence, Kyre, Susanne, Lamb, James, Mc Guinness, C, Mills, C, Nguyen, Harold, Nikolic, Milan, Lowette, Steven, Rebassoo, Finn, Ribnik, Jacob, Richman, Jeffrey, Rubinstein, Noah, Sanhueza, S, Shah, Yousaf Syed, Simms, L, Staszak, D, Stoner, J, Stuart, David, Swain, Sanjay Kumar, Vlimant, Jean-Roch, White, Dean, Ulmer, Keith, Wagner, Stephen Robert, Bagby, Linda, Bhat, Pushpalatha C, Burkett, Kevin, Cihangir, Selcuk, Gutsche, Oliver, Jensen, Hans, Johnson, Mark, Luzhetskiy, Nikolay, Mason, David, Miao, Ting, Moccia, Stefano, Noeding, Carsten, Ronzhin, Anatoly, Skup, Ewa, Spalding, William J, Spiegel, Leonard, Tkaczyk, Slawek, Yumiceva, Francisco, Zatserklyaniy, Andriy, Zerev, E, Anghel, Ioana Maria, Bazterra, Victor Eduardo, Gerber, Cecilia Elena, Khalatian, S, Shabalina, Elizaveta, Baringer, Philip, Bean, Alice, Chen, Jie, Hinchey, Carl Louis, Martin, Christophe, Moulik, Tania, Robinson, Richard, Gritsan, Andrei, Lae, Chung Khim, Tran, Nhan Viet, Everaerts, Pieter, Hahn, Kristan Allan, Harris, Philip, Nahn, Steve, Rudolph, Matthew, Sung, Kevin, Betchart, Burton, Demina, Regina, Gotra, Yury, Korjenevski, Sergey, Miner, Daniel Carl, Orbaker, Douglas, Christofek, Leonard, Hooper, Ryan, Landsberg, Greg, Nguyen, Duong, Narain, Meenakshi, Speer, Thomas, and Tsang, Ka Vang

Subjects
Physics::Instrumentation and Detectors, Astrophysics::High Energy Astrophysical Phenomena, Astrophysics::Instrumentation and Methods for Astrophysics, Detectors and Experimental Techniques
Abstract

The subsystems of the CMS silicon strip tracker were integrated and commissioned at the Tracker Integration Facility (TIF) in the period from November 2006 to July 2007. As part of the commissioning, large samples of cosmic ray data were recorded under various running conditions in the absence of a magnetic field. Cosmic rays detected by scintillation counters were used to trigger the readout of up to 15\,\% of the final silicon strip detector, and over 4.7~million events were recorded. This document describes the cosmic track reconstruction and presents results on the performance of track and hit reconstruction as from dedicated analyses.

Published
2008

24. Petal Integration for the CMS Tracker End Caps

Author

Bergauer, Thomas, Dragicevic, Marko, Friedl, Markus, Hansel, S, Hrubec, Josef, Krammer, Manfred, Pernicka, Manfred, Beaumont, Willem, De Wolf, Eddi A, Bouhali, Othmane, Clerbaux, Barbara, Dewulf, Jean-Paul, De Lentdecker, Gilles, Mahmoud, Tariq, Neukermans, Lionel, Van der Velde, C, Vanlaer, Pascal, Wickens, John, D'Hondt, Jorgen, Goorens, Robert, Heyninck, Jan, Tavernier, Stefaan, Udo, Fred, Van Lancker, Luc, Bonnet, Jean-Luc, De Callatay, Bernard, Delaere, Christophe, Florins, Benoit, Grégoire, Ghislain, Keutgen, Thomas, Lemaître, Vincent, Michotte, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Rouby, Xavier, Teyssier, Daniel, Van der Donckt, M, Ageron, Michel, Baulieu, Guillaume, Bonnevaux, Alain, Boudoul, Gaelle, Chabanat, Eric, Chabert, Eric Christian, Contardo, Didier, Della Negra, Rodolphe, Estre, Nicolas, Giraud, Noël, Haroutunian, Roger, Lumb, Nicholas, Mirabito, Laurent, Perriès, Stephane, Trocmé, Benjamin, Vanzetto, Sylvain, Agram, Jean-Laurent, Drouhin, Frédéric, Ernenwein, Jean-Pierre, Fontaine, Jean-Charles, Berst, Jean-Daniel, Brom, Jean-Marie, Didierjean, Francois, Hosselet, J, Goerlach, Ulrich, Graehling, Philippe, Gross, Laurent, Juillot, Pierre, Lounis, Abdenour, Maazouzi, Chaker, Ollivetto, C, Strub, Roger, Van Hove, Pierre, Adolphi, Roman, Brauer, Richard, Braunschweig, Wolfgang, Esser, Hans, Feld, Lutz, Karpinski, Waclaw, Klein, Katja, König, Stefan, Kosbow, M, Lübelsmeyer, Klaus, Olzem, Jan, Ostapchuk, Andrey, Pandoulas, Demetrios, Pierschel, Gerhard, Schael, Stefan, Schmitz, Stefan Antonius, Schultz von Dratzig, Arndt, Siedling, Rolf, Weber, Markus, Wittmer, Bruno, Wlochal, Michael, Beissel, Franz, Bock, E, Flossdorf, E, Flügge, Günter, Hermanns, Thomas, Heydhausen, Dirk, Jahn, Dieter, Kaussen, Gordon, Linn, Alexander, Poettgens, Michael, Pooth, Oliver, Stahl, Achim, Zoeller, Marc Henning, Butz, Erik, Flucke, Gero, Klanner, Robert, Pein, Uwe, Schirm, Norbert, Schleper, Peter, Steinbruck, G, Stoye, Markus, Van Staa, Rolf, Atz, Bernd, Blüm, Peter, de Boer, Wim, Bogelsbacher, F, Barvich, Tobias, Dehm, Philip, Dierlamm, Alexander, Dirkes, Guido, Fahrer, Manuel, Fernández, J, Frey, Martin, Furgeri, Alexander, Gregoriev, E, Hartmann, Frank, Heier, Stefan, Kaminski, Jochen, Ledermann, Bernhard, Muller, Th, Piaseki, C, Sabellek, Andreas, Simonis, Hans-Jürgen, Steck, Pia, Theel, Andreas, Weiler, Thomas, Weseler, Siegfried, Zhukov, Valery, and Freudenreich, Klaus

Subjects
Detectors and Experimental Techniques
Abstract

This note describes the assembly and testing of the 292 petals built for the CMS Tracker End Caps from the beginning of 2005 until the summer of 2006. Due to the large number of petals to be assembled and the need to reach a throughput of 10 to 15 petals per week, a distributed integration approach was chosen. This integration was carried out by the following institutes: I. and III. Physikalisches Institut - RWTH Aachen University; IIHE, ULB \& VUB Universities, Brussels; Hamburg University; IEKP, Karlsruhe University; FYNU, Louvain University; IPN, Lyon University; and IPHC, Strasbourg University. Despite the large number of petals which needed to be reworked to cope with a late-discovered module issue, the quality of the petals is excellent with less than 0.2\% bad channels.

Published
2008

25. The Energetic Particle Telescope: First Results

Author

UCL - SST/IRMP - Institut de recherche en mathématique et physique, Pierrard, Viviane, Lopez Rosson, G., Borremans, K., Lemaire, Joseph, Maes, J., Bonnewijn, S., Van Ransbeeck, E., Neefs, E., Cyamukungu, Mathias, Benck, Sylvie, Bonnet, Jean-Luc, Borisov, Stanislav, Cabrera Jamoulle, Juan, Grégoire, G., Semaille, C., Creve, G., De Saedeleer, J., Desoete, B., Preud’homme, F., Anciaux, M., Helderweirt, A., Litefti, K., Brun, N., Pauwels, D., Quevrin, C., Moreau, D., Punkkinen, R., Valtonen, E., Hajdas, W., Nieminen, P., UCL - SST/IRMP - Institut de recherche en mathématique et physique, Pierrard, Viviane, Lopez Rosson, G., Borremans, K., Lemaire, Joseph, Maes, J., Bonnewijn, S., Van Ransbeeck, E., Neefs, E., Cyamukungu, Mathias, Benck, Sylvie, Bonnet, Jean-Luc, Borisov, Stanislav, Cabrera Jamoulle, Juan, Grégoire, G., Semaille, C., Creve, G., De Saedeleer, J., Desoete, B., Preud’homme, F., Anciaux, M., Helderweirt, A., Litefti, K., Brun, N., Pauwels, D., Quevrin, C., Moreau, D., Punkkinen, R., Valtonen, E., Hajdas, W., and Nieminen, P.

Abstract

The Energetic Particle Telescope (EPT) is a new compact and modular ionizing particle spectrometer that was launched on 7 May 2013 to a LEO polar orbit at an altitude of 820 km onboard the ESA satellite PROBA-V. First results show electron, proton and helium ion fluxes in the South Atlantic Anomaly (SAA) and at high latitudes, with high flux increases during SEP (Solar Energetic Particles) events and geomagnetic storms. These observations help to improve the understanding of generation and loss processes associated to the Van Allen radiation belts

Published
2014

26. The Energetic Particle Telescope (EPT) on Board PROBA-V: Description of a New Science-Class Instrument for Particle Detection in Space

Author

Cyamukungu, Mathias, primary, Benck, Sylvie, additional, Borisov, Stanislav, additional, Gregoire, Ghislain, additional, Cabrera, Juan, additional, Bonnet, Jean-Luc, additional, Desoete, Bart, additional, Preudrhomme, Frank, additional, Semaille, Christophe, additional, Creve, Glenn, additional, De Saedeleer, Juergen, additional, Ilsen, Stijn, additional, De Busser, Luc, additional, Pierrard, Viviane, additional, Bonnewijn, Sabrina, additional, Maes, Jeroen, additional, Van Ransbeeck, Emiel, additional, Neefs, Eddy, additional, Lemaire, Joseph, additional, Valtonen, Eino, additional, Punkkinen, Risto, additional, Anciaux, Michel, additional, Litefti, Karim, additional, Brun, Nicolas, additional, Pauwels, Dirk, additional, Quevrin, Cyril, additional, Moreau, Didier, additional, Helderweirt, Anuschka, additional, Hajdas, Wojtek, additional, and Nieminen, Petteri, additional

Published
2014
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29. Alignment of the CMS Silicon Strip Tracker during stand-alone Commissioning

Author

UCL - Autre, Adam, W., Bonnet, Jean-Luc, Bruno, Giacomo, De Callatay, B., Florins, B., Giammanco, Andrea, Gregoire, G., Keutgen, Thomas, Kcira, D., Lemaitre, Vincent, Michotte, D., Militaru, O., Piotrzkowski, Krzysztof, Quertenmont, Loic, Roberfroid, V., Rouby, Xavier, Teyssier, D., UCL - Autre, Adam, W., Bonnet, Jean-Luc, Bruno, Giacomo, De Callatay, B., Florins, B., Giammanco, Andrea, Gregoire, G., Keutgen, Thomas, Kcira, D., Lemaitre, Vincent, Michotte, D., Militaru, O., Piotrzkowski, Krzysztof, Quertenmont, Loic, Roberfroid, V., Rouby, Xavier, and Teyssier, D.

Abstract

The results of the CMS tracker alignment analysis are presented using the data from cosmic tracks, optical survey information, and the laser alignment system at the Tracker Integration Facility at CERN. During several months of operation in the spring and summer of 2007, about five million cosmic track events were collected with a partially active CMS Tracker. This allowed us to perform first alignment of the active silicon modules with the cosmic tracks using three different statistical approaches; validate the survey and laser alignment system performance; and test the stability of Tracker structures under various stresses and temperatures ranging from +15C to -15C. Comparison with simulation shows that the achieved alignment precision in the barrel part of the tracker leads to residual distributions similar to those obtained with a random misalignment of 50 (80) microns in the outer (inner) part of the barrel. Comment: 41 pages, 63 postscript figures, submitted to JINST

Published
2009

30. Stand-alone Cosmic Muon Reconstruction Before Installation of the CMS Silicon Strip Tracker

Author

UCL - Autre, UCL - SST/IRMP - Institut de recherche en mathématique et physique, CMS Tracker Collaboration, Adam, W., Bonnet, Jean-Luc, Bruno, Giacomo Luca, de Callatay, Bernard, Florins, Benoît, Giammanco, Andrea, Grégoire, Ghislain, Keutgen, Thomas, Kcira, Dorian, Lemaitre, Vincent, Michotte de Welle, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Quertenmont, Loic, Roberfroid, Vincent, Rouby, Xavier, Teyssier, Daniel, UCL - Autre, UCL - SST/IRMP - Institut de recherche en mathématique et physique, CMS Tracker Collaboration, Adam, W., Bonnet, Jean-Luc, Bruno, Giacomo Luca, de Callatay, Bernard, Florins, Benoît, Giammanco, Andrea, Grégoire, Ghislain, Keutgen, Thomas, Kcira, Dorian, Lemaitre, Vincent, Michotte de Welle, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Quertenmont, Loic, Roberfroid, Vincent, Rouby, Xavier, and Teyssier, Daniel

Abstract

The subsystems of the CMS silicon strip tracker were integrated and commissioned at the Tracker Integration Facility (TIF) in the period from November 2006 to July 2007. As part of the commissioning, large samples of cosmic ray data were recorded under various running conditions in the absence of a magnetic field. Cosmic rays detected by scintillation counters were used to trigger the readout of up to 15% of the final silicon strip detector, and over 4.7 million events were recorded. This document describes the cosmic track reconstruction and presents results on the performance of track and hit reconstruction as from dedicated analyses. Comment: Added missing LaTex command / no change in contents w.r.t. v1

Published
2009

31. CMS Tracker Alignment at the Integration Facility

Author

UCL - SC/PHYS - Département de physique, UCL - SC/SC - Faculté des sciences, UCL - LS/AULS - Autres services de logistique scientifique générale, Assouak, Samia, Bonnet, Jean-Luc, Bruno, Giacomo, de Callatay, Bernard, Favart, Denis, Florins, Benoît, Forton, Eric, Grégoire, Ghislain, Keutgen, Thomas, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Rouby, Xavier, Teyssier, Daniel, van der Aa, Olivier, Giammanco, Andrea, Kcira, Dorian, Quertenmont, Loic, Roberfroid, Vincent, Vander Donckt, Muriel, Delaere, Christophe, UCL - SC/PHYS - Département de physique, UCL - SC/SC - Faculté des sciences, UCL - LS/AULS - Autres services de logistique scientifique générale, Assouak, Samia, Bonnet, Jean-Luc, Bruno, Giacomo, de Callatay, Bernard, Favart, Denis, Florins, Benoît, Forton, Eric, Grégoire, Ghislain, Keutgen, Thomas, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Rouby, Xavier, Teyssier, Daniel, van der Aa, Olivier, Giammanco, Andrea, Kcira, Dorian, Quertenmont, Loic, Roberfroid, Vincent, Vander Donckt, Muriel, and Delaere, Christophe

Abstract

The results of the CMS tracker alignment analysis are presented using the data from cosmic tracks, optical survey information, and the laser alignment system at the Tracker Integration Facility at CERN. During several months of operation in the spring and summer of 2007, about five million cosmic track events were collected with a partially active CMS Tracker. This allowed us to perform first alignment of the active silicon modules with the cosmic tracks using three different statistical approaches; validate the survey and laser alignment system performance; and test the stability of Tracker structures under various stresses and temperatures ranging from $+15^circ$C to $-15^circ$C. Comparison with simulation shows that the achieved alignment precision in the barrel part of the tracker leads to residual distributions similar to those obtained with a random misalignment of $50$ ($80$)~$mu$m in the outer (inner) part of the barrel.

Published
2009

32. The effect of highly ionising particles on the CMS silicon strip tracker

Author

UCL - SC/PHYS - Département de physique, UCL - SC/SC - Faculté des sciences, Assouak, Samia, Bonnet, Jean-Luc, de Callatay, Bernard, Bruno, Giacomo, de Favereau de Jeneret, Jérôme, Delaere, Christophe, de Visscher, Simon, Favart, Denis, Grégoire, Ghislain, Keutgen, Thomas, Leibenguth, Guillaume, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Ninane, Alain, Ovyn, Séverine, Piotrzkowski, Krzysztof, Roberfroid, Vincent, Rouby, Xavier, van der Aa, Olivier, Vander Donckt, Muriel, UCL - SC/PHYS - Département de physique, UCL - SC/SC - Faculté des sciences, Assouak, Samia, Bonnet, Jean-Luc, de Callatay, Bernard, Bruno, Giacomo, de Favereau de Jeneret, Jérôme, Delaere, Christophe, de Visscher, Simon, Favart, Denis, Grégoire, Ghislain, Keutgen, Thomas, Leibenguth, Guillaume, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Ninane, Alain, Ovyn, Séverine, Piotrzkowski, Krzysztof, Roberfroid, Vincent, Rouby, Xavier, van der Aa, Olivier, and Vander Donckt, Muriel

Abstract

Inelastic nuclear collisions of hadrons incident on silicon sensors can generate secondary highly ionising particles (HIPs) and deposit as much energy within the sensor bulk as several hundred minimum ionising particles. The large signals generated by these ‘HIP events’ can momentarily saturate the APV25 front-end readout chip for the silicon strip tracker (SST) sub-detector of the compact muon solenoid (CMS) experiment, resulting in deadtime in the detector readout system. This paper presents studies of this phenomenon through simulation, laboratory measurements and dedicated beam tests. A proposed change to a front-end component to reduce the APV25 sensitivity to HIP events is also examined. The results are used to infer the expected effect on the performance of the CMS SST at the future large hadron collider. The induced inefficiencies are at the percent level and will have a negligible effect on the physics performance of the SST.

Published
2005

33. Design and test beam performance of substructures of the CMS tracker end caps

Author

UCL - SC/PHYS - Département de physique, UCL - SC/SC - Faculté des sciences, UCL - UCL/UCL - Secteur UCL, Assouak, Samia, Bonnet, Jean-Luc, Bruno, Giacomo Luca, de Callataÿ, Bernard, de Favereau de Jeneret, Jérôme, Delaere, Christophe, de Visscher, Simon, Favart, Denis, Grégoire, Ghislain, Keutgen, Thomas, Leibenguth, Guillaume, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Ninane, Alain, Ovyn, Séverine, Piotrzkowski, Krzysztof, Roberfroid, Vincent, Rouby, Xavier, van der Aa, Olivier, Vander Donckt, M., UCL - SC/PHYS - Département de physique, UCL - SC/SC - Faculté des sciences, UCL - UCL/UCL - Secteur UCL, Assouak, Samia, Bonnet, Jean-Luc, Bruno, Giacomo Luca, de Callataÿ, Bernard, de Favereau de Jeneret, Jérôme, Delaere, Christophe, de Visscher, Simon, Favart, Denis, Grégoire, Ghislain, Keutgen, Thomas, Leibenguth, Guillaume, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Ninane, Alain, Ovyn, Séverine, Piotrzkowski, Krzysztof, Roberfroid, Vincent, Rouby, Xavier, van der Aa, Olivier, and Vander Donckt, M.

Abstract

With its total active silicon area of about 200 squaremetres and more than 15000 silicon modules the silicon strip tracker of the CMS experiment at the LHC will be the largest silicon strip detector ever built. While the performance of single silicon modules has already been tested extensively in various test beam experiments, the performance of larger integrated substructures also had to be studied with a particle beam before launching mass production, in order to ensure the envisaged performance of the overall system. In May/June 2004 the performance of a system of two petals of the tracker end caps (TEC), which represents about 1% of the full TEC and forms an autonomous unit in terms of data acquisition, has been studied in a test beam experiment at CERN. In this document the test beam experiment is described and results are presented.

Published
2005

39. Evaluation of a Dual Sensor Rate Responsive Pacing System Based on a New Concept.

Author

Bonnet, Jean-Luc, Géroux, Laurence, and Cazeau, Serge

Subjects
CARDIAC pacemakers, CARDIAC pacing, HEART beat, EXERCISE tests, IMPLANTED cardiovascular instruments, PULMONARY function tests
Abstract

The minute ventilation is known to be one of the most physiological indicators of exercise. A curvilinear relationship between VE and the normal sinus rhythm (NSR) has been demonstrated in healthy patients. The aim of this study is to show that a pacemaker based on a VE sensor can reproduce such a relationship. Eighty-one patients received a Talent DR 213 (ELA Medical, Montrouge, France) pacemaker with a third-generation rate responsive algorithm. At 1-month follow-up, the patients underwent a treadmill exercise test, after which three groups were defined: group 1 had 6 patients who were 100% paced throughout the exercise test; group 2 had 10 patients who maintained NSR throughout the test; and group 3 had 12 patients who had cardiopulmonary recording during the exercise test. In group 1 patients, the simulation function computed the simulated rate (sim-rate), which was compared to the sensor-driven rate (SDR). In group 2 patients, sim-rate was compared to the NSR. In group 3 patients, cardiac and metabolic reserves were compared to determine the appropriateness of the rate response to exercise (HRR% vs MR%). The results showed that the mean correlation coefficient between sim-rate and SDR was 0.983 ± 0.005 (P < 0.001); the mean correlation coefficient between NSR and SDR was 0.92 ± 0.07 (P < 0.001); and a linear relationship was found between HRR% and MR%, with a mean slope of 1.1 ± 0.2 that was significantly equal to the theoretical value of 1 (P = NS). In conclusion, combining an activity-driven sensor with a physiological sensor allows the preservation of a physiological rate response during exercise. [ABSTRACT FROM AUTHOR]

Published
1998

40. Automatic Adaptation of the Basic Pacing Rate in Response to Minute Ventilation.

Author

Limousin, Marcel, Pioger, Guy, Bonnet, Jean-Luc, and Geroux, Laurence

Subjects
CARDIAC pacing, TACHYCARDIA, HEART beat, ARRHYTHMIA, HEART ventricles, MEDICAL equipment
Abstract

Rate responsive pacing based on minute ventilation (VE) correlates highly with metabolic demand. This type of sensing also recognizes extended periods of rest. The Chorum pacemaker includes a rate responsive algorithm that modulates the basic rate according to phases of activity versus sleep. Forty-six patients (mean age 78 ± 15), received a Chorum pacemaker for atrioventricular block in 17 cases, sick sinus syndrome in 25, and mixed disorders in 4. Holter monitoring was performed to analyze heart rate and to examine the circadian adaptation of the minimal pacing rate. The mean basic rate was programmed at 63 ± 5 beats/min, and the sleep rate at 52 ± 4 beats/mm. Seventeen patients had spontaneous heart rates consistently above the programmed basic rate, and 6 had sustained supraventricular tachyarrhythmias. One-half of the patients had periods of pacing at the programmed sleep rate. The mean diurnal pacing rate was 68 ± 5 beats/mm compared to a mean nocturnal rate of 60 ± 4 beats/mm (P < 0.0001). The average time spent at the basic rate was 37 ± 30 mm (0-110) during daytime (4%), versus 242 ± 153 mm (20-477) at night (45%, P < 0.0001). No adverse effect was observed in this patient population. VE allows a reliable detection of the sleeping periods as well as an adjustment of the basic rate in accordance. Caution is advised in cases of bradycardia dependent tachyarrhythmias. [ABSTRACT FROM AUTHOR]

Published
1998

41. Measurement of Minute Ventilation with Different DDDR Pacemaker Electrode Configurations.

Author

Bonnet, Jean-Luc, Ritter, Philippe, and Pioger, Guy

Subjects
CARDIAC pacemakers, ELECTRODES, IMPLANTED cardiovascular instruments, OXYGEN, BIOMEDICAL engineering, MEDICAL equipment
Abstract

A rate responsive minute ventilation (VE) pacemaker was implanted in 49 patients (70.8 ± 40.0 years). A Chorus RM 7034 pacemaker was implanted in 43 patients and an Opus RM 4534 in six patients. Four sensor configurations were compared: atrial configuration (bipolar atrial lead) in 34 patients; ventricular configuration (bipolar ventricular lead) in 6 patients; unipolar configuration (double unipolar leads) in 6 patients; and floating configuration (VDD single-pass lead) in 3 patients. The patients carried out 57 exercise tests in all with cardiopulmonary recording (CPX). Real VE and oxygen consumption (VO2) were recorded by the CPX, the VE measured by the sensor (VE sensor) was recorded in the pacemaker memory. The mean correlation between VE and VE sensor was 0.90 ± 0.08 (P <0.001) and between VO2 and VE sensor was 0.86 ± 0.10 (P <0.001). The mean correlation between VE and VE sensor by configuration type were as follows: atrial configuration = 0.89 ± 0.08; ventricular configuration = 0.95 ± 0.05; unipolar configuration = 0.87 ± 0.14; and floating configuration = 0.88 ± 0.05. In conclusion, VE may be reliably measured using different electrode configurations. A study conducted in a larger population should allow one to conclude that uniploar electrodes can be used in VDDR, AAIR, VVIR, or DDDR modes to measure VE. [ABSTRACT FROM AUTHOR]

Published
1998

42. Mode Switch Despite Undersensing of Atrial Fibrillation in DDD Pacing.

Author

Bonnet, Jean-Luc, Brusseau, Elisabeth, Limousin, Marcel, and Cazeau, Serge

Subjects
TACHYCARDIA, ARRHYTHMIA, ATRIAL fibrillation, ATRIAL arrhythmias, CARDIAC pacing, ARRHYTHMIA treatment, ELECTRIC stimulation
Abstract

Mode switching algorithms are commonly used to protect the ventricles against high rates induced by atrial tachycardia. In the case of atrial fibrillation (AF), the response of these algorithms depends on the quality of atrial sensing. The Chorum 7234 DDDB pacemaker uses a new mode switching algorithm, based on a statistical analysis of the atrial rhythm. It includes two criteria of diagnosis: ‘high’ if more than 28 of 32 cycles are abnormally accelerated; and ‘low’ if more than 36 of 64 cycles are abnormally accelerated. Methods: From a taped database of electrophysiological studies, episodes of AF lasting more than 2 minutes were selected. A tape recorder replayed the atrial signals into an external Chorum device. Each episode was replayed eight times with a programmed atrial sensitivity increasing from 0.4–2.0 mV. For each criterion of diagnosis and each programmed sensitivity, the percentage of atrial sensing, the time to switching, and the mean ventricular rate were measured. Ten episodes of AF from 10 patients (9 men and 1 woman; ages 62 ± 16 years) were included: 1.95 ± 0.97 m V and 196 ± 64 ms. The sensitivity of the algorithm to diagnose atrial tachycardia reached 100%, for an atrial sensitivity set between 0.4 and 1.0 mV. The mean percentages of atrial sensed events were 74% ± 18% and 46% ± 9% for the ‘high’ and ‘low’ criteria, respectively. The mean diagnostic times were 28 ± 26 seconds and 68 ± 27 seconds, respectively. Sensing of < 23% of AF events resulted in failure to diagnose the arrhythmias by both algorithms. In the event of diagnostic failure, the mean ventricular pacing rate was 79 ± 9 ppm. Conclusion: Up to an atrial sensitivity of 1 mV, 100% of AF episodes were diagnosed. The Chorum mode switching algorithms are 100% reliable if > 45 % of the AF waves are sensed. In the event of switching failure, the ventricle is protected by an average rate remaining below 80 ppm. [ABSTRACT FROM AUTHOR]

Published
1996
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View/download PDF

43. Etude du poinçonnement d'une série stratifiée par le déplacement d'une écaille chevauchante : exemples expérimentaux et naturels

Author

Bonnet, Jean Luc, Laboratoire Interdisciplinaire de Recherche Impliquant la Géologie et la Mécanique (LIRIGM), Université Joseph Fourier - Grenoble 1 (UJF), Université Scientifique et Médicale de Grenoble, Pierre Vialon, and Talour, Pascale

Subjects
[SDU.STU.TE]Sciences of the Universe [physics]/Earth Sciences/Tectonics, Modèle analogique, Alpes occidentales, Schistosité, [SDE.MCG]Environmental Sciences/Global Changes, [SDU.STU.TE] Sciences of the Universe [physics]/Earth Sciences/Tectonics, Essai laboratoire, Chevauchement, Glissement, Plissement, Ecaille, Structures arquées, [SDE.MCG] Environmental Sciences/Global Changes, Orogénie alpine, Déformation superposée, Poinçonnement, Analyse Structurale, Jura, Microtectonique, Décollement, Linéations, Tectonique tangentielle, Réseau de fractures
Abstract

La modélisation analogique effectuée consiste à déformer une couverture stratifiée (représentée par des feuillets de paraffine calibrés : niveaux compétents, séparés par un enduit degraisse aux silicones = niveaux incompétents) qui peut glisser sur son socle rigide, par un poinçon simulant une écaille (représentée par un bloc indéformable) et agissant soit par son déplacement dans le plan des couches, soit par son poids, perpendiculairement à celles-ci. Par nécessité de schématisation le rôle tangentiel du poinçon est séparé de son rôle gravitaire en deux expériences distinctes. Des règles de répartition des structures obtenues sont déduites de ces modèles contrôlés. Les résultats de la modélisation sont ensuite testés sur deux exemples de terrain. L'arc du front pennique valaisan, qui parait, cartographiquement, dû à un ecoulement entre les deux poinçons passifs du Mont Blanc et de l'Aar, ne peut pas en fait être interprété en termes de poinçonnement horizontal. C'est la surrection tardive des massifs bordiers qui provoque la forme arquée du front des nappes. L'arc du Jura correspond mieux aux résultats expérimentaux. Les structures analysées dans cette région semblent tout à fait compatibles avec un glissement et une déformation contrastée en zones concentriques, de la couverture sédimentaire sur son socle. La mise en mouvement serait due à la poussée vers le NW du Bassin molassique suisse, lui-même indéformé et déplacé sous l'influence des schevauchement crustaux alpins plus méridionaux. La confrontation des données expérimentales et de terrain permet de donner les règles utilisables pour déterminer si un ensemble de structures est bien le résultat du déplacement d'une écaille chevauchante agissant par poinçonnement de son avant pays. Les deux tests effectués sur le terrain montrent que ces règles sont réellement pratiques et discriminantes. Il en ressort qu'il est surtout important de distinguer entre les déformations situées au front du poinçon (forte amplitude des plis, déversements et chevauchements, structures imbriquées, extension perpendiculaire aux directions structurales axiales) et celles qui sont situées à son flanc (moindre amplitude des plis, extension parallèle aux axes, décrochement...) ., pas de résumé

Published
1983

44. Performance studies of the CMS Strip Tracker before installation

Author

Adam, Wolfgang, Bergauer, Thomas, Dragicevic, Marko, Friedl, Markus, Fruhwirth, R, Hansel, S, Hrubec, Josef, Krammer, Manfred, Oberegger, Margit, Pernicka, Manfred, Schmid, Siegfried, Stark, Roland, Steininger, Helmut, Uhl, Dieter, Waltenberger, Wolfgang, Widl, Edmund, Van Mechelen, Pierre, Cardaci, Marco, Beaumont, Willem, de Langhe, Eric, de Wolf, Eddi A, Delmeire, Evelyne, Hashemi, Majid, Bouhali, Othmane, Charaf, Otman, Clerbaux, Barbara, Dewulf, Jean-Paul, Elgammal, Sherif, Hammad, Gregory Habib, de Lentdecker, Gilles, Marage, Pierre Edouard, Vander Velde, Catherine, Vanlaer, Pascal, Wickens, John, Adler, Volker, Devroede, Olivier, De Weirdt, Stijn, D'Hondt, Jorgen, Goorens, Robert, Heyninck, Jan, Maes, Joris, Mozer, Matthias Ulrich, Tavernier, Stefaan, Van Lancker, Luc, Van Mulders, Petra, Villella, Ilaria, Wastiels, C, Bonnet, Jean-Luc, Bruno, Giacomo, De Callatay, Bernard, Florins, Benoit, Giammanco, Andrea, Gregoire, Ghislain, Keutgen, Thomas, Kcira, Dorian, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Quertermont, L, Roberfroid, Vincent, Rouby, Xavier, Teyssier, Daniel, Daubie, Evelyne, Anttila, Erkki, Czellar, Sandor, Engstrom, Pauli, Harkonen, J, Karimaki, V, Kostesmaa, J, Kuronen, Auli, Lampen, Tapio, Linden, Tomas, Luukka, Panja-Riina, Maenpaa, T, Michal, Sebastien, Tuominen, Eija, Tuominiemi, Jorma, Ageron, Michel, Baulieu, Guillaume, Bonnevaux, Alain, Boudoul, Gaelle, Chabanat, Eric, Chabert, Eric Christian, Chierici, Roberto, Contardo, Didier, Della Negra, Rodolphe, Dupasquier, Thierry, Gelin, Georges, Giraud, Noël, Guillot, Gérard, Estre, Nicolas, Haroutunian, Roger, Lumb, Nicholas, Perries, Stephane, Schirra, Florent, Trocme, Benjamin, Vanzetto, Sylvain, Agram, Jean-Laurent, Blaes, Reiner, Drouhin, Frédéric, Ernenwein, Jean-Pierre, Fontaine, Jean-Charles, Berst, Jean-Daniel, Brom, Jean-Marie, Didierjean, Francois, Goerlach, Ulrich, Graehling, Philippe, Gross, Laurent, Hosselet, J, Juillot, Pierre, Lounis, Abdenour, Maazouzi, Chaker, Olivetto, Christian, Strub, Roger, Van Hove, Pierre, Anagnostou, Georgios, Brauer, Richard, Esser, Hans, Feld, Lutz, Karpinski, Waclaw, Klein, Katja, Kukulies, Christoph, Olzem, Jan, Ostapchuk, Andrey, Pandoulas, Demetrios, Pierschel, Gerhard, Raupach, Frank, Schael, Stefan, Schwering, Georg, Sprenger, Daniel, Thomas, Maarten, Weber, Markus, Wittmer, Bruno, Wlochal, Michael, Beissel, Franz, Bock, E, Flugge, G, Gillissen, C, Hermanns, Thomas, Heydhausen, Dirk, Jahn, Dieter, Kaussen, Gordon, Linn, Alexander, Perchalla, Lars, Poettgens, Michael, Pooth, Oliver, Stahl, Achim, Zoeller, Marc Henning, Buhmann, Peter, Butz, Erik, Flucke, Gero, Hamdorf, Richard Helmut, Hauk, Johannes, Klanner, Robert, Pein, Uwe, Schleper, Peter, Steinbruck, G, Blum, P, De Boer, Wim, Dierlamm, Alexander, Dirkes, Guido, Fahrer, Manuel, Frey, Martin, Furgeri, Alexander, Hartmann, Frank, Heier, Stefan, Hoffmann, Karl-Heinz, Kaminski, Jochen, Ledermann, Bernhard, Liamsuwan, Thiansin, 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Giammanco, Andrea, Gregoire, Ghislain, Keutgen, Thomas, Kcira, Dorian, Lemaitre, Vincent, Michotte, Daniel, Militaru, Otilia, Piotrzkowski, Krzysztof, Quertermont, L, Roberfroid, Vincent, Rouby, Xavier, Teyssier, Daniel, Daubie, Evelyne, Anttila, Erkki, Czellar, Sandor, Engstrom, Pauli, Harkonen, J, Karimaki, V, Kostesmaa, J, Kuronen, Auli, Lampen, Tapio, Linden, Tomas, Luukka, Panja-Riina, Maenpaa, T, Michal, Sebastien, Tuominen, Eija, Tuominiemi, Jorma, Ageron, Michel, Baulieu, Guillaume, Bonnevaux, Alain, Boudoul, Gaelle, Chabanat, Eric, Chabert, Eric Christian, Chierici, Roberto, Contardo, Didier, Della Negra, Rodolphe, Dupasquier, Thierry, Gelin, Georges, Giraud, Noël, Guillot, Gérard, Estre, Nicolas, Haroutunian, Roger, Lumb, Nicholas, Perries, Stephane, Schirra, Florent, Trocme, Benjamin, Vanzetto, Sylvain, Agram, Jean-Laurent, Blaes, Reiner, Drouhin, Frédéric, Ernenwein, Jean-Pierre, Fontaine, Jean-Charles, Berst, Jean-Daniel, Brom, Jean-Marie, Didierjean, Francois, Goerlach, Ulrich, Graehling, Philippe, Gross, Laurent, Hosselet, J, Juillot, Pierre, Lounis, Abdenour, Maazouzi, Chaker, Olivetto, Christian, Strub, Roger, Van Hove, Pierre, Anagnostou, Georgios, Brauer, Richard, Esser, Hans, Feld, Lutz, Karpinski, Waclaw, Klein, Katja, Kukulies, Christoph, Olzem, Jan, Ostapchuk, Andrey, Pandoulas, Demetrios, Pierschel, Gerhard, Raupach, Frank, Schael, Stefan, Schwering, Georg, Sprenger, Daniel, Thomas, Maarten, Weber, Markus, Wittmer, Bruno, Wlochal, Michael, Beissel, Franz, Bock, E, Flugge, G, Gillissen, C, Hermanns, Thomas, Heydhausen, Dirk, Jahn, Dieter, Kaussen, Gordon, Linn, Alexander, Perchalla, Lars, Poettgens, Michael, Pooth, Oliver, Stahl, Achim, Zoeller, Marc Henning, Buhmann, Peter, Butz, Erik, Flucke, Gero, Hamdorf, Richard Helmut, Hauk, Johannes, Klanner, Robert, Pein, Uwe, Schleper, Peter, Steinbruck, G, Blum, P, De Boer, Wim, Dierlamm, Alexander, Dirkes, Guido, Fahrer, Manuel, Frey, Martin, Furgeri, Alexander, Hartmann, Frank, Heier, Stefan, Hoffmann, Karl-Heinz, Kaminski, Jochen, Ledermann, Bernhard, Liamsuwan, Thiansin, Muller, S, Muller, Th, Schilling, Frank-Peter, Simonis, Hans-Jürgen, Steck, Pia, Zhukov, Valery, Cariola, P, De Robertis, Giuseppe, Ferorelli, Raffaele, Fiore, Luigi, Preda, M, Sala, Giuliano, Silvestris, Lucia, Tempesta, Paolo, Zito, Giuseppe, Creanza, Donato, De Filippis, Nicola, De Palma, Mauro, Giordano, Domenico, Maggi, Giorgio, Manna, Norman, My, Salvatore, Selvaggi, Giovanna, Albergo, Sebastiano, Chiorboli, Massimiliano, Costa, Salvatore, Galanti, Mario, Giudice, Nunzio, Guardone, Nunzio, Noto, Francesco, Potenza, Renato, Saizu, Mirela Angela, Sparti, V, Sutera, Concetta, Tricomi, Alessia, Tuve, Cristina, Brianzi, Mirko, Civinini, Carlo, Maletta, Fernando, Manolescu, Florentina, Meschini, Marco, Paoletti, Simone, Sguazzoni, Giacomo, Broccolo, B, Ciulli, Vitaliano, D'Alessandro, Raffaello, Focardi, Ettore, Frosali, Simone, Genta, Chiara, Landi, Gregorio, Lenzi, Piergiulio, Macchiolo, Anna, Magini, Nicolo, Parrini, Giuliano, Scarlini, Enrico, Cerati, Giuseppe Benedetto, Azzi, Patrizia, Bacchetta, Nicola, Candelori, Andrea, Dorigo, Tommaso, Kaminsky, A, Karaevski, S, Khomenkov, Volodymyr, Reznikov, Sergey, Tessaro, Mario, Bisello, Dario, De Mattia, Marco, Giubilato, Piero, Loreti, Maurizio, Mattiazzo, Serena, Nigro, Massimo, Paccagnella, Alessandro, Pantano, Devis, Pozzobon, Nicola, Tosi, Mia, Bilei, Gian Mario, Checcucci, Bruno, Fano, Livio, Servoli, Leonello, Ambroglini, Filippo, Babucci, Ezio, Benedetti, Daniele, Biasini, Maurizio, Caponeri, Benedetta, Covarelli, Roberto, Giorgi, Marco, Lariccia, Paolo, Mantovani, Giancarlo, Marcantonini, Marta, Postolache, Vasile, Santocchia, Attilio, Spiga, Daniele, Bagliesi, Giuseppe, Balestri, Gabriele, Berretta, Luca, Bianucci, S, Boccali, Tommaso, Bosi, Filippo, Bracci, Fabrizio, Castaldi, Rino, Ceccanti, Marco, Cecchi, Roberto, Cerri, Claudio, Cucoanes, Andi Sebastian, Dell'Orso, Roberto, Dobur, Didar, Dutta, Suchandra, Giassi, Alessandro, Giusti, Simone, Kartashov, Dmitry, Kraan, Aafke, Lomtadze, Teimuraz, Lungu, George-Adrian, Magazzu, Guido, Mammini, Paolo, Mariani, Filippo, Martinelli, Giovanni, Moggi, Andrea, Palla, Fabrizio, Palmonari, Francesco, Petragnani, Giulio, Profeti, Alessandro, Raffaelli, Fabrizio, Rizzi, Domenico, Sanguinetti, Giulio, Sarkar, Subir, Sentenac, Daniel, Serban, Alin Titus, Slav, Adrian, Soldani, A, Spagnolo, Paolo, Tenchini, Roberto, Tolaini, Sergio, Venturi, Andrea, Verdini, Piero Giorgio, Vos, Marcel, Zaccarelli, Luciano, Avanzini, Carlo, Basti, Andrea, Benucci, Leonardo, Bocci, Andrea, Cazzola, Ugo, Fiori, Francesco, Linari, Stefano, Massa, Maurizio, Messineo, Alberto, Segneri, Gabriele, Tonelli, Guido, Azzurri, Paolo, Bernardini, Jacopo, Borrello, Laura, Calzolari, Federico, Foa, Lorenzo, Gennai, Simone, Ligabue, Franco, Petrucciani, Giovanni, Rizzi, Andrea, Yang, Zong-Chang, Benotto, Franco, Demaria, Natale, Dumitrache, Floarea, Farano, R, Borgia, Maria Assunta, Castello, 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Korjenevski, Sergey, Miner, Daniel Carl, Orbaker, Douglas, Christofek, Leonard, Hooper, Ryan, Landsberg, Greg, Nguyen, Duong, Narain, Meenakshi, Speer, Thomas, and Tsang, Ka Vang

Abstract

In March 2007 the assembly of the Silicon Strip Tracker was completed at the Tracker Integration Facility at CERN. Nearly 15% of the detector was instrumented using cables, fiber optics, power supplies, and electronics intended for the operation at the LHC. A local chiller was used to circulate the coolant for low temperature operation. In order to understand the efficiency and alignment of the strip tracker modules, a cosmic ray trigger was implemented. From March through July 4.5 million triggers were recorded. This period, referred to as the Sector Test, provided practical experience with the operation of the Tracker, especially safety, data acquisition, power, and cooling systems. This paper describes the performance of the strip system during the Sector Test, which consisted of five distinct periods defined by the coolant temperature. Significant emphasis is placed on comparisons between the data and results from Monte Carlo studies.

47. On-off closed-loop control of vagus nerve stimulation for the adaptation of heart rate.

Author

Ugalde HR, Le Rolle V, Bel A, Bonnet JL, Andreu D, Mabo P, Carrault G, and Hernández AI

Subjects
Algorithms, Animals, Electricity, Electrocardiography, Sheep, Adaptation, Physiological, Heart Rate physiology, Vagus Nerve physiology, Vagus Nerve Stimulation methods
Abstract

Vagus nerve stimulation (VNS) is a potential therapeutic approach in a number of clinical applications. Although VNS is commonly delivered in an open-loop approach, it is now recognized that closed-loop approaches may be necessary to optimize the therapy and minimize side effects of neuro-stimulation devices. In this paper, we describe a prototype system for real-time control of the instantaneous heart rate, working synchronously with the heart period. As a first step, an on-off control method has been integrated. The system is evaluated on one sheep with induced heart failure, showing the interest of the proposed approach.

Published
2014
Full Text
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48. Influence of Vagus Nerve Stimulation parameters on chronotropism and inotropism in heart failure.

Author

Rousselet L, Le Rolle V, Ojeda D, Guiraud D, Hagége A, Bel A, Bonnet JL, Mabo P, Carrault G, and Hernández AI

Subjects
Animals, Autonomic Nervous System physiopathology, Electrocardiography, Heart Rate physiology, Muscle Contraction, Myocardial Infarction physiopathology, Sheep, Signal Processing, Computer-Assisted, Heart Failure physiopathology, Vagus Nerve physiology, Vagus Nerve Stimulation methods
Abstract

Vagus Nerve Stimulation (VNS) has been shown to be useful in heart failure patients, including antiarrhythmic effects, improvement of cardiac function and reduction of the mortality. However, the optimal configuration of VNS can be a difficult task, since there are several adjustable parameters, such as current amplitude (mA), pulse width (ms), burst frequency (Hz), number of pulses and, in the case of cardiac-triggered VNS, the delay (ms) between the R-wave and the beginning of the stimulation. The objective of this paper is to analyse the effect of these parameters, and their interaction, on the chronotropic and inotropic responses to vagal stimulation. 306 VNS sequences were tested on 12 sheep with induced heart failure. Autonomic markers of the chronotropic (changes in RR interval) and inotropic (changes in dP/dtmax) effects were extracted from the observed data. In order to analyse the influence of stimulation parameters on these markers, a sensitivity analysis method was applied. Results illustrate the strong interaction between the delay and the others parameters. The number of pulses, the current and the frequency seem to be particularly influent on chronotropism and inotropism although the effect of the frequency is highly non-linear or it depends on other parameters.

Published
2014
Full Text
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