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4. Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study

Author

Abdallah, A, Abentroth, AL, Acheimastos, V, Agunaoun, M, Al Bisher, HM, Al Ghuzlan, A, Alakus, H, Alkan, M, Almaraz Almaraz, MC, Amram, K, Anesidis, S, Anestiadou, E, Angelucci, D, Ansaldo, GL, Antonopoulou, MI, Arciniegas, M, Armellin, C, Arredondo Saldaña, G, Astl, J, Athanasakis, E, Avenia, S, Aydın, H, Baba, B, Babala, J, Banús, MV, Barba-Valadez, LA, Barcons, SV, Battafarano, F, Bayat, A, Bella, RMC, Benariba, F, Bernardi, S, Bignami, EG, Bitenc, M, Bitsianis, S, Bolaños de la Torre, JDD, Bonati, E, Bonetti, T, Borges, FA, Bouchagier, K, Boudina, M, Bourial, A, Breuskin, I, Brock, P, Bruns, C, Burlacu, MC, Burton, T, Buta, M, Buzanakov, D, Caliseo, C, Callanan, D, Calu, V, Cameselle-Teijeiro, JM, Camilo-Junior, DJ, Canberk, S, Candalise, V, Candanedo-Gonzalez, F, Carrillo Lizarazo, LJ, Carvalho, GB, Casallas, D, Casolino, C, Castellani, L, Castillo Morales, C, Chambon, G, Chatzipavlidou, V, Chernikov, R, Chorti, A, Chow, TCM, Chrisoulidou, A, Chrysos, E, Conrado-Neto, S, Cordova García, D, Corigliano, A, Crocco, A, Cuesta, A, Čukman, M, Curto, LS, Damilano, RA, D'Anna, R, De, M, De Virgilio, A, Dellaportas, D, Demarquet, L, Devresse, A, Di Meo, G, Diaz Pedrero, R, Dimitrov, D, Dmitry, Z, Domínguez Garijo, P, Dulgeroglu, O, Dural, AC, Eksi, A, El Hammoumi, M, El Kaoui, H, Eleni, G, Elliyanti, A, Ersöz, Ş, Escobar-Jiménez, M, Fedorova, L, Feeley, L, Fernández Rodríguez, E, Ferreli, F, Filoia, A, Fingeret, A, Francescato, A, Gaino, F, Galiandro, F, Gallegos-Hernández, JF, Garas, G, García Lorenzo, F, García-Chávez, JP, Gaudiello, M, Gay, S, Gerasimos, S, Gerek, M, Gervasi, R, Giordano, A, Gjeloshi, B, Gocký, L, Golubinskaya, E, González Romero, S, González-Mínguez, C, Goran, M, Gosman, A, Granados Garcia, M, Greco, E, Grünbart, M, Grützmann, R, Guerlain, J, Guirao, XG, Guzey, D, Hajjij, A, Hamdy, O, Hameed, MS, Hauth, LA, Hernández-Acevedo, JD, Hernandez-Carrillo, JF, Hevilla Sánchez, F, Hoi, H, Hongkwon, K, Hu Zhu, R, Huang, E, Hyeung Kyoo, K, Ignjatovic, V, Ioannidis, A, Iossa, A, Işık, A, James, D, Jung Hoon, L, Kara, H, Karajovic, J, Kartini, D, Khambri, D, Kholová, I, Kisiel, M, Knežević, M, Koh, YQ, Konca, C, Kosmidis, C, Kotsovolis, G, Kowalski, LP, Kralik, R, Kuczma, P, Kuravi, BG, Kurnia, A, Kyriaki, V, Lai, CM, Lallemant, B, Lardhi, AA, Leboulleux, S, Lee, JW, Lelli, G, Leutner, M, Lim, MY, Lim, CM, Llanos, A, Lo, X, Loderer, T, López-Corrales, MA, Ludwig, M, Magnabosco, FF, Maheo, C, Maia, AL, Makay, O, Maksimova, P, Mallick, S, Mallouk, C, Mamani, Z, Mandal, S, Manyalich Blasi, M, Marincola, G, Marulanda, M, Mavromati, M, Mayilvaganan, S, Metso, S, Micalizzi, A, Michalopoulos, A, Min-Su, K, Miron, A, Mishra, AK, Misso, C, Mittermair, C, Morosán Allo, Y, Mourad, M, Moysidis, M, Nabhan, F, Nasiri, R, Nastos, C, Ngiam, KY, Nomine-Criqui, C, Ntziovara, AM, Nuño Vázquez-Garza, JM, Nutautiene, V, Obtulovičová, K, O'Keeffe, L, Okudur, NO, Ossola, P, Ovejero Merino, E, Ozdemir, M, Pangonis, A, Panigoro, SS, Panuzi, A, Papaconstantinou, D, Pardo Matamoros, N, Paschou, S, Pasculli, A, Paterakis, K, Peiris, K, Pennestrì, F, Peppa, M, Perdikaris, P, Perdikaris, I, Pérez-Soto, RH, Piana, S, Piccoli, M, Pietrasanta, D, Placentino, G, Pliakos, I, Polistena, A, Pongtippan, A, Potard, G, Quinn, V, Rahul, P, Ramos, T, Rankin, A, Ratnayake, P, Reuto-Castillo, J, Ridolfo, A, Rios-Valencia, J, Riss, P, Rival, E, Rivillas, J, Roi, D, Rollo, EM, Romanchishen, A, Romito, M, Rotnagl, J, Rovcanin, B, Russo, G, Sabol, M, Saki, S, Saleh, S, Salih, A, Saltiki, A, Salvador-Camarmo, G, Samal, DK, Sánchez-Flores, S, Sapalidis, K, Sarin, D, Sarin, H, Savkovic, N, Scheffel, RS, Scheinpflug, AL, Scheuba, C, Scheyer, N, Schmidt, M, Senashova, O, Serafini, E, Serrano Arévalo, ML, Shank, J, Shindo, ML, Shoshkova, M, Shvan, M, Sičák, M, Silva, TG, Simó Guerrero, O, Skuletic, V, Slijepcevic, N, Slovic, Z, Soares, P, Somova, A, Soto, S, Spiezia, S, Stankovic, V, Stephenson, KJ, Straub, E, Summa, M, Surani, S, Syed, AA, Symeonidis, S, Taciak, A, Tarallo, M, Tarle, A, Tasis, N, Tausanovic, K, Tchabashvili, L, Thierry, M, Tokarczyk, U, Toma, EA, Topuz, S, Torresan, F, Uras, C, Vaccaro, C, Valdés de Anca, Á, Valentini, M, Varaldo, E, Vartanian, JG, Verras, GI, Vithanage, A, Wijayalathge, H, Wiriyaamornchai, P, Wong, YLC, Wongwattana, P, Xenaki, S, Xie, S, Xu, M, Yang, W, Yilmaz, S, Yılmaz, YF, Yotsov, T, Zahid, MT, Zielke, A, Medas, Fabio, Dobrinja, Chiara, Al-Suhaimi, Ebtesam Abdullah, Altmeier, Julia, Anajar, Said, Arikan, Akif Enes, Azaryan, Irina, Bains, Lovenish, Basili, Giancarlo, Bolukbasi, Hakan, Bononi, Marco, Borumandi, Farzad, Bozan, Mehmet Buğra, Brenta, Gabriela, Brunaud, Laurent, Brunner, Maximilian, Buemi, Antoine, Canu, Gian Luigi, Cappellacci, Federico, Cartwright, Sara Burchfield, Castells Fusté, Ignasi, Cavalheiro, Beatriz, Cavallaro, Giuseppe, Chala, Andres, Chan, Shun Yan Bryant, Chaplin, John, Cheema, Mustafa Sajjad, Chiapponi, Costanza, Chiofalo, Maria Grazia, Chrysos, Emmanuel, D'Amore, Annamaria, de Cillia, Michael, De Crea, Carmela, de Manzini, Nicolò, de Matos, Leandro Luongo, De Pasquale, Loredana, Del Rio, Paolo, Demarchi, Marco Stefano, Dhiwakar, Muthuswamy, Donatini, Gianluca, Dora, Jose Miguel, D'Orazi, Valerio, Doulatram Gamgaram, Viyey Kishore, Eismontas, Vitalijus, Kabiri, El Hassane, El Malki, Hadj Omar, Elzahaby, Islam, Enciu, Octavian, Eskander, Antoine, Feroci, Francesco, Figueroa-Bohorquez, David, Filis, Dimitrios, Gorostidi, François, Frías-Fernández, Pedro, Gamboa-Dominguez, Armando, Genc, Volkan, Giordano, Davide, Gómez-Pedraza, Antonio, Graceffa, Giuseppa, Griffin, James, Guerreiro, Sofia Cuco, Gupta, Karan, Gupta, Keshav Kumar, Gurrado, Angela, Hajiioannou, Jiannis, Hakala, Tommi, Harahap, Wirsma Arif, Hargitai, Lindsay, Hartl, Dana, Hellmann, Andrzej, Hlozek, Jiri, Hoang, Van Trung, Iacobone, Maurizio, Innaro, Nadia, Ioannidis, Orestis, Jang, J H Isabelle, Xavier-Junior, Jose Candido, Jovanovic, Milan, Kaderli, Reto Martin, Kakamad, Fahmi, Kaliszewski, Krzysztof, Karamanliev, Martin, Katoh, Hiroshi, Košec, Andro, Kovacevic, Bozidar, Kowalski, Luiz Paulo, Králik, Robert, Yadav, Sanjay Kumar, Kumorová, Adriána, Lampridis, Savvas, Lasithiotakis, Konstantinos, Leclere, Jean-Christophe, Leong, Eugene Kwong Fei, Leow, Melvin Khee-Shing, Lim, James Y, Lino-Silva, Leonardo S, Liu, Shirley Yuk Wah, Llorach, Núria Perucho, Lombardi, Celestino Pio, López-Gómez, Javier, Lori, Eleonora, Quintanilla-Dieck, Lourdes, Lucchini, Roberta, Madani, Amin, Manatakis, Dimitrios, Markovic, Ivan, Materazzi, Gabriele, Mazeh, Haggi, Mercante, Giuseppe, Meyer-Rochow, Goswin Yason, Mihaljevic, Olgica, Miller, Julie A, Minuto, Michele, Monacelli, Massimo, Mulita, Francesk, Mullineris, Barbara, Muñoz-de-Nova, José Luis, Muradás Girardi, Fábio, Nader, Saki, Napadon, Tangjaturonrasme, Nastos, Constantinos, Offi, Chiara, Ronen, Ohad, Oragano, Luigi, Orois, Aida, Pan, Yongqin, Panagiotidis, Emmanouil, Panchangam, Ramakanth Bhargav, Papavramidis, Theodosios, Parida, Pradipta Kumar, Paspala, Anna, Pérez, Òscar Vidal, Petrovic, Sabrina, Raffaelli, Marco, Ramacciotti, Constanza Fernanda, Ratia Gimenez, Tomas, Rivo Vázquez, Ángel, Roh, Jong-Lyel, Rossi, Leonardo, Sanabria, Alvaro, Santeerapharp, Alena, Semenov, Arseny, Seneviratne, Sanjeewa, Serdar, Altinay, Sheahan, Patrick, Sheppard, Sean C, Slotcavage, Rachel L, Smaxwil, Constantin, Kim, Soo Young, Sorrenti, Salvatore, Spartalis, Eleftherios, Sriphrapradang, Chutintorn, Testini, Mario, Turk, Yigit, Tzikos, George, Vabalayte, Kristina, Vargas-Osorio, Kelly, Vázquez Rentería, Rafael Sebastián, Velázquez-Fernández, David, Vithana, Sanura Malinda Pallegoda, Yücel, Levent, Yulian, Erwin Danil, Zahradnikova, Petra, Zarogoulidis, Paul, Ziablitskaia, Evgeniia, Zolotoukho, Anna, and Calò, Pietro Giorgio

Published
2023
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5. 5-year Follow-up of Reimplanted Parathyroid Glands in Forearm Subcutaneous Tissue During Thyroidectomy. A Confirmation of Graft Vitality in a Large Series of Patients

Author

Lelli, Giulio, primary, Micalizzi, Alessandra, additional, Gurrado, Angela, additional, Bononi, Marco, additional, Iossa, Angelo, additional, De Angelis, Francesco, additional, Di Meo, Diletta, additional, Fassari, Alessia, additional, Testini, Mario, additional, and Cavallaro, Giuseppe, additional

Published
2024
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6. Early Parathyroid Hormone (PTH) level as a predictor of post-surgical hypoparathyroidism.

Author

Ossola, Paolo, primary, Borasi, Andrea, additional, Barberis, Andrea, additional, Marola, Silvia, additional, Ghiglione, Francesco, additional, Pentassuglia, Giuseppe, additional, Puligheddu, Barbara, additional, Brustio, Paolo Riccardo, additional, Messuti, Ilaria, additional, Bononi, Marco, additional, Leli, Renzo, additional, and Lanfranco, Fabio, additional

Published
2024
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9. Computer-aided diagnostic system for thyroid nodule sonographic evaluation outperforms the specificity of less experienced examiners

Author

Fresilli, Daniele, Grani, Giorgio, De Pascali, Maria Luna, Alagna, Gregorio, Tassone, Eleonora, Ramundo, Valeria, Ascoli, Valeria, Bosco, Daniela, Biffoni, Marco, Bononi, Marco, D’Andrea, Vito, Frattaroli, Fabrizio, Giacomelli, Laura, Solskaya, Yana, Polti, Giorgia, Pacini, Patrizia, Guiban, Olga, Gallo Curcio, Raffaele, Caratozzolo, Marcello, and Cantisani, Vito

Published
2020
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12. Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study

Author

Medas, Fabio, primary, Dobrinja, Chiara, additional, Al-Suhaimi, Ebtesam Abdullah, additional, Altmeier, Julia, additional, Anajar, Said, additional, Arikan, Akif Enes, additional, Azaryan, Irina, additional, Bains, Lovenish, additional, Basili, Giancarlo, additional, Bolukbasi, Hakan, additional, Bononi, Marco, additional, Borumandi, Farzad, additional, Bozan, Mehmet Buğra, additional, Brenta, Gabriela, additional, Brunaud, Laurent, additional, Brunner, Maximilian, additional, Buemi, Antoine, additional, Canu, Gian Luigi, additional, Cappellacci, Federico, additional, Cartwright, Sara Burchfield, additional, Castells Fusté, Ignasi, additional, Cavalheiro, Beatriz, additional, Cavallaro, Giuseppe, additional, Chala, Andres, additional, Chan, Shun Yan Bryant, additional, Chaplin, John, additional, Cheema, Mustafa Sajjad, additional, Chiapponi, Costanza, additional, Chiofalo, Maria Grazia, additional, Chrysos, Emmanuel, additional, D'Amore, Annamaria, additional, de Cillia, Michael, additional, De Crea, Carmela, additional, de Manzini, Nicolò, additional, de Matos, Leandro Luongo, additional, De Pasquale, Loredana, additional, Del Rio, Paolo, additional, Demarchi, Marco Stefano, additional, Dhiwakar, Muthuswamy, additional, Donatini, Gianluca, additional, Dora, Jose Miguel, additional, D'Orazi, Valerio, additional, Doulatram Gamgaram, Viyey Kishore, additional, Eismontas, Vitalijus, additional, Kabiri, El Hassane, additional, El Malki, Hadj Omar, additional, Elzahaby, Islam, additional, Enciu, Octavian, additional, Eskander, Antoine, additional, Feroci, Francesco, additional, Figueroa-Bohorquez, David, additional, Filis, Dimitrios, additional, Gorostidi, François, additional, Frías-Fernández, Pedro, additional, Gamboa-Dominguez, Armando, additional, Genc, Volkan, additional, Giordano, Davide, additional, Gómez-Pedraza, Antonio, additional, Graceffa, Giuseppa, additional, Griffin, James, additional, Guerreiro, Sofia Cuco, additional, Gupta, Karan, additional, Gupta, Keshav Kumar, additional, Gurrado, Angela, additional, Hajiioannou, Jiannis, additional, Hakala, Tommi, additional, Harahap, Wirsma Arif, additional, Hargitai, Lindsay, additional, Hartl, Dana, additional, Hellmann, Andrzej, additional, Hlozek, Jiri, additional, Hoang, Van Trung, additional, Iacobone, Maurizio, additional, Innaro, Nadia, additional, Ioannidis, Orestis, additional, Jang, J H Isabelle, additional, Xavier-Junior, Jose Candido, additional, Jovanovic, Milan, additional, Kaderli, Reto Martin, additional, Kakamad, Fahmi, additional, Kaliszewski, Krzysztof, additional, Karamanliev, Martin, additional, Katoh, Hiroshi, additional, Košec, Andro, additional, Kovacevic, Bozidar, additional, Kowalski, Luiz Paulo, additional, Králik, Robert, additional, Yadav, Sanjay Kumar, additional, Kumorová, Adriána, additional, Lampridis, Savvas, additional, Lasithiotakis, Konstantinos, additional, Leclere, Jean-Christophe, additional, Leong, Eugene Kwong Fei, additional, Leow, Melvin Khee-Shing, additional, Lim, James Y, additional, Lino-Silva, Leonardo S, additional, Liu, Shirley Yuk Wah, additional, Llorach, Núria Perucho, additional, Lombardi, Celestino Pio, additional, López-Gómez, Javier, additional, Lori, Eleonora, additional, Quintanilla-Dieck, Lourdes, additional, Lucchini, Roberta, additional, Madani, Amin, additional, Manatakis, Dimitrios, additional, Markovic, Ivan, additional, Materazzi, Gabriele, additional, Mazeh, Haggi, additional, Mercante, Giuseppe, additional, Meyer-Rochow, Goswin Yason, additional, Mihaljevic, Olgica, additional, Miller, Julie A, additional, Minuto, Michele, additional, Monacelli, Massimo, additional, Mulita, Francesk, additional, Mullineris, Barbara, additional, Muñoz-de-Nova, José Luis, additional, Muradás Girardi, Fábio, additional, Nader, Saki, additional, Napadon, Tangjaturonrasme, additional, Nastos, Constantinos, additional, Offi, Chiara, additional, Ronen, Ohad, additional, Oragano, Luigi, additional, Orois, Aida, additional, Pan, Yongqin, additional, Panagiotidis, Emmanouil, additional, Panchangam, Ramakanth Bhargav, additional, Papavramidis, Theodosios, additional, Parida, Pradipta Kumar, additional, Paspala, Anna, additional, Pérez, Òscar Vidal, additional, Petrovic, Sabrina, additional, Raffaelli, Marco, additional, Ramacciotti, Constanza Fernanda, additional, Ratia Gimenez, Tomas, additional, Rivo Vázquez, Ángel, additional, Roh, Jong-Lyel, additional, Rossi, Leonardo, additional, Sanabria, Alvaro, additional, Santeerapharp, Alena, additional, Semenov, Arseny, additional, Seneviratne, Sanjeewa, additional, Serdar, Altinay, additional, Sheahan, Patrick, additional, Sheppard, Sean C, additional, Slotcavage, Rachel L, additional, Smaxwil, Constantin, additional, Kim, Soo Young, additional, Sorrenti, Salvatore, additional, Spartalis, Eleftherios, additional, Sriphrapradang, Chutintorn, additional, Testini, Mario, additional, Turk, Yigit, additional, Tzikos, George, additional, Vabalayte, Kristina, additional, Vargas-Osorio, Kelly, additional, Vázquez Rentería, Rafael Sebastián, additional, Velázquez-Fernández, David, additional, Vithana, Sanura Malinda Pallegoda, additional, Yücel, Levent, additional, Yulian, Erwin Danil, additional, Zahradnikova, Petra, additional, Zarogoulidis, Paul, additional, Ziablitskaia, Evgeniia, additional, Zolotoukho, Anna, additional, Calò, Pietro Giorgio, additional, Abdallah, A, additional, Abentroth, AL, additional, Acheimastos, V, additional, Agunaoun, M, additional, Al Bisher, HM, additional, Al Ghuzlan, A, additional, Alakus, H, additional, Alkan, M, additional, Almaraz Almaraz, MC, additional, Amram, K, additional, Anesidis, S, additional, Anestiadou, E, additional, Angelucci, D, additional, Ansaldo, GL, additional, Antonopoulou, MI, additional, Arciniegas, M, additional, Armellin, C, additional, Arredondo Saldaña, G, additional, Astl, J, additional, Athanasakis, E, additional, Avenia, S, additional, Aydın, H, additional, Baba, B, additional, Babala, J, additional, Banús, MV, additional, Barba-Valadez, LA, additional, Barcons, SV, additional, Battafarano, F, additional, Bayat, A, additional, Bella, RMC, additional, Benariba, F, additional, Bernardi, S, additional, Bignami, EG, additional, Bitenc, M, additional, Bitsianis, S, additional, Bolaños de la Torre, JDD, additional, Bonati, E, additional, Bonetti, T, additional, Borges, FA, additional, Bouchagier, K, additional, Boudina, M, additional, Bourial, A, additional, Breuskin, I, additional, Brock, P, additional, Bruns, C, additional, Burlacu, MC, additional, Burton, T, additional, Buta, M, additional, Buzanakov, D, additional, Caliseo, C, additional, Callanan, D, additional, Calu, V, additional, Cameselle-Teijeiro, JM, additional, Camilo-Junior, DJ, additional, Canberk, S, additional, Candalise, V, additional, Candanedo-Gonzalez, F, additional, Carrillo Lizarazo, LJ, additional, Carvalho, GB, additional, Casallas, D, additional, Casolino, C, additional, Castellani, L, additional, Castillo Morales, C, additional, Chambon, G, additional, Chatzipavlidou, V, additional, Chernikov, R, additional, Chorti, A, additional, Chow, TCM, additional, Chrisoulidou, A, additional, Chrysos, E, additional, Conrado-Neto, S, additional, Cordova García, D, additional, Corigliano, A, additional, Crocco, A, additional, Cuesta, A, additional, Čukman, M, additional, Curto, LS, additional, Damilano, RA, additional, D'Anna, R, additional, De, M, additional, De Virgilio, A, additional, Dellaportas, D, additional, Demarquet, L, additional, Devresse, A, additional, Di Meo, G, additional, Diaz Pedrero, R, additional, Dimitrov, D, additional, Dmitry, Z, additional, Domínguez Garijo, P, additional, Dulgeroglu, O, additional, Dural, AC, additional, Eksi, A, additional, El Hammoumi, M, additional, El Kaoui, H, additional, Eleni, G, additional, Elliyanti, A, additional, Ersöz, Ş, additional, Escobar-Jiménez, M, additional, Fedorova, L, additional, Feeley, L, additional, Fernández Rodríguez, E, additional, Ferreli, F, additional, Filoia, A, additional, Fingeret, A, additional, Francescato, A, additional, Gaino, F, additional, Galiandro, F, additional, Gallegos-Hernández, JF, additional, Garas, G, additional, García Lorenzo, F, additional, García-Chávez, JP, additional, Gaudiello, M, additional, Gay, S, additional, Gerasimos, S, additional, Gerek, M, additional, Gervasi, R, additional, Giordano, A, additional, Gjeloshi, B, additional, Gocký, L, additional, Golubinskaya, E, additional, González Romero, S, additional, González-Mínguez, C, additional, Goran, M, additional, Gosman, A, additional, Granados Garcia, M, additional, Greco, E, additional, Grünbart, M, additional, Grützmann, R, additional, Guerlain, J, additional, Guirao, XG, additional, Guzey, D, additional, Hajjij, A, additional, Hamdy, O, additional, Hameed, MS, additional, Hauth, LA, additional, Hernández-Acevedo, JD, additional, Hernandez-Carrillo, JF, additional, Hevilla Sánchez, F, additional, Hoi, H, additional, Hongkwon, K, additional, Hu Zhu, R, additional, Huang, E, additional, Hyeung Kyoo, K, additional, Ignjatovic, V, additional, Ioannidis, A, additional, Iossa, A, additional, Işık, A, additional, James, D, additional, Jung Hoon, L, additional, Kara, H, additional, Karajovic, J, additional, Kartini, D, additional, Khambri, D, additional, Kholová, I, additional, Kisiel, M, additional, Knežević, M, additional, Koh, YQ, additional, Konca, C, additional, Kosmidis, C, additional, Kotsovolis, G, additional, Kowalski, LP, additional, Kralik, R, additional, Kuczma, P, additional, Kuravi, BG, additional, Kurnia, A, additional, Kyriaki, V, additional, Lai, CM, additional, Lallemant, B, additional, Lardhi, AA, additional, Leboulleux, S, additional, Lee, JW, additional, Lelli, G, additional, Leutner, M, additional, Lim, MY, additional, Lim, CM, additional, Llanos, A, additional, Lo, X, additional, Loderer, T, additional, López-Corrales, MA, additional, Ludwig, M, additional, Magnabosco, FF, additional, Maheo, C, additional, Maia, AL, additional, Makay, O, additional, Maksimova, P, additional, Mallick, S, additional, Mallouk, C, additional, Mamani, Z, additional, Mandal, S, additional, Manyalich Blasi, M, additional, Marincola, G, additional, Marulanda, M, additional, Mavromati, M, additional, Mayilvaganan, S, additional, Metso, S, additional, Micalizzi, A, additional, Michalopoulos, A, additional, Min-Su, K, additional, Miron, A, additional, Mishra, AK, additional, Misso, C, additional, Mittermair, C, additional, Morosán Allo, Y, additional, Mourad, M, additional, Moysidis, M, additional, Nabhan, F, additional, Nasiri, R, additional, Nastos, C, additional, Ngiam, KY, additional, Nomine-Criqui, C, additional, Ntziovara, AM, additional, Nuño Vázquez-Garza, JM, additional, Nutautiene, V, additional, Obtulovičová, K, additional, O'Keeffe, L, additional, Okudur, NO, additional, Ossola, P, additional, Ovejero Merino, E, additional, Ozdemir, M, additional, Pangonis, A, additional, Panigoro, SS, additional, Panuzi, A, additional, Papaconstantinou, D, additional, Pardo Matamoros, N, additional, Paschou, S, additional, Pasculli, A, additional, Paterakis, K, additional, Peiris, K, additional, Pennestrì, F, additional, Peppa, M, additional, Perdikaris, P, additional, Perdikaris, I, additional, Pérez-Soto, RH, additional, Piana, S, additional, Piccoli, M, additional, Pietrasanta, D, additional, Placentino, G, additional, Pliakos, I, additional, Polistena, A, additional, Pongtippan, A, additional, Potard, G, additional, Quinn, V, additional, Rahul, P, additional, Ramos, T, additional, Rankin, A, additional, Ratnayake, P, additional, Reuto-Castillo, J, additional, Ridolfo, A, additional, Rios-Valencia, J, additional, Riss, P, additional, Rival, E, additional, Rivillas, J, additional, Roi, D, additional, Rollo, EM, additional, Romanchishen, A, additional, Romito, M, additional, Rotnagl, J, additional, Rovcanin, B, additional, Russo, G, additional, Sabol, M, additional, Saki, S, additional, Saleh, S, additional, Salih, A, additional, Saltiki, A, additional, Salvador-Camarmo, G, additional, Samal, DK, additional, Sánchez-Flores, S, additional, Sapalidis, K, additional, Sarin, D, additional, Sarin, H, additional, Savkovic, N, additional, Scheffel, RS, additional, Scheinpflug, AL, additional, Scheuba, C, additional, Scheyer, N, additional, Schmidt, M, additional, Senashova, O, additional, Serafini, E, additional, Serrano Arévalo, ML, additional, Shank, J, additional, Shindo, ML, additional, Shoshkova, M, additional, Shvan, M, additional, Sičák, M, additional, Silva, TG, additional, Simó Guerrero, O, additional, Skuletic, V, additional, Slijepcevic, N, additional, Slovic, Z, additional, Soares, P, additional, Somova, A, additional, Soto, S, additional, Spiezia, S, additional, Stankovic, V, additional, Stephenson, KJ, additional, Straub, E, additional, Summa, M, additional, Surani, S, additional, Syed, AA, additional, Symeonidis, S, additional, Taciak, A, additional, Tarallo, M, additional, Tarle, A, additional, Tasis, N, additional, Tausanovic, K, additional, Tchabashvili, L, additional, Thierry, M, additional, Tokarczyk, U, additional, Toma, EA, additional, Topuz, S, additional, Torresan, F, additional, Uras, C, additional, Vaccaro, C, additional, Valdés de Anca, Á, additional, Valentini, M, additional, Varaldo, E, additional, Vartanian, JG, additional, Verras, GI, additional, Vithanage, A, additional, Wijayalathge, H, additional, Wiriyaamornchai, P, additional, Wong, YLC, additional, Wongwattana, P, additional, Xenaki, S, additional, Xie, S, additional, Xu, M, additional, Yang, W, additional, Yilmaz, S, additional, Yılmaz, YF, additional, Yotsov, T, additional, Zahid, MT, additional, and Zielke, A, additional

Published
2023
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14. Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study

Author

Medas, Fabio, Dobrinja, Chiara, Al-Suhaimi, Ebtesam Abdullah, Altmeier, Julia, Anajar, Said, Arikan, Akif Enes, Azaryan, Irina, Bains, Lovenish, Basili, Giancarlo, Bolukbasi, Hakan, Bononi, Marco, Borumandi, Farzad, Bozan, Mehmet Buğra, Brenta, Gabriela, Brunaud, Laurent, Brunner, Maximilian, Buemi, Antoine, Canu, Gian Luigi, Cappellacci, Federico, Cartwright, Sara Burchfield, Castells Fusté, Ignasi, Cavalheiro, Beatriz, Cavallaro, Giuseppe, Chala, Andres, Chan, Shun Yan Bryant, Chaplin, John, Cheema, Mustafa Sajjad, Chiapponi, Costanza, Chiofalo, Maria Grazia, Chrysos, Emmanuel, D'Amore, Annamaria, de Cillia, Michael, De Crea, Carmela, de Manzini, Nicolò, de Matos, Leandro Luongo, De Pasquale, Loredana, Del Rio, Paolo, Demarchi, Marco Stefano, Dhiwakar, Muthuswamy, Donatini, Gianluca, Dora, Jose Miguel, D'Orazi, Valerio, Doulatram Gamgaram, Viyey Kishore, Eismontas, Vitalijus, Kabiri, El Hassane, El Malki, Hadj Omar, Elzahaby, Islam, Enciu, Octavian, Eskander, Antoine, Feroci, Francesco, Figueroa-Bohorquez, David, Filis, Dimitrios, François, Gorostidi, Frías-Fernández, Pedro, Gamboa-Dominguez, Armando, Genc, Volkan, Giordano, Davide, Gómez-Pedraza, Antonio, Graceffa, Giuseppa, Griffin, James, Guerreiro, Sofia Cuco, Gupta, Karan, Gupta, Keshav Kumar, Gurrado, Angela, Hajiioannou, Jiannis, Hakala, Tommi, Harahap, Wirsma Arif, Hargitai, Lindsay, Hartl, Dana, Hellmann, Andrzej, Hlozek, Jiri, Hoang, Van Trung, Iacobone, Maurizio, Innaro, Nadia, Ioannidis, Orestis, Jang, J H Isabelle, Xavier-Junior, Jose Candido, Jovanovic, Milan, Kaderli, Reto Martin, Kakamad, Fahmi, Kaliszewski, Krzysztof, Karamanliev, Martin, Katoh, Hiroshi, Košec, Andro, Kovacevic, Bozidar, Kowalski, Luiz Paulo, Králik, Robert, Yadav, Sanjay Kumar, Kumorová, Adriána, Lampridis, Savvas, Lasithiotakis, Konstantinos, Leclere, Jean-Christophe, Leong, Eugene Kwong Fei, Leow, Melvin Khee-Shing, Lim, James Y, Lino-Silva, Leonardo S, Liu, Shirley Yuk Wah, Llorach, Núria Perucho, Lombardi, Celestino Pio, López-Gómez, Javier, Lori, Eleonora, Quintanilla-Dieck, Lourdes, Lucchini, Roberta, Madani, Amin, Manatakis, Dimitrios, Markovic, Ivan, Materazzi, Gabriele, Mazeh, Haggi, Mercante, Giuseppe, Meyer-Rochow, Goswin Yason, Mihaljevic, Olgica, Miller, Julie A, Minuto, Michele, Monacelli, Massimo, Mulita, Francesk, Mullineris, Barbara, Muñoz-de-Nova, José Luis, Muradás Girardi, Fábio, Nader, Saki, Napadon, Tangjaturonrasme, Nastos, Constantinos, Offi, Chiara, Ronen, Ohad, Oragano, Luigi, Orois, Aida, Pan, Yongqin, Panagiotidis, Emmanouil, Panchangam, Ramakanth Bhargav, Papavramidis, Theodosios, Parida, Pradipta Kumar, Paspala, Anna, Pérez, Òscar Vidal, Petrovic, Sabrina, Raffaelli, Marco, Ramacciotti, Constanza Fernanda, Ratia Gimenez, Tomas, Rivo Vázquez, Ángel, Roh, Jong-Lyel, Rossi, Leonardo, Sanabria, Alvaro, Santeerapharp, Alena, Semenov, Arseny, Seneviratne, Sanjeewa, Serdar, Altinay, Sheahan, Patrick, Sheppard, Sean C, Slotcavage, Rachel L, Smaxwil, Constantin, Kim, Soo Young, Sorrenti, Salvatore, Spartalis, Eleftherios, Sriphrapradang, Chutintorn, Testini, Mario, Turk, Yigit, Tzikos, George, Vabalayte, Kristina, Vargas-Osorio, Kelly, Vázquez Rentería, Rafael Sebastián, Velázquez-Fernández, David, Vithana, Sanura Malinda Pallegoda, Yücel, Levent, Yulian, Erwin Danil, Zahradnikova, Petra, Zarogoulidis, Paul, Ziablitskaia, Evgeniia, Zolotoukho, Anna, and Calò, Pietro Giorgio

Subjects
610 Medicine & health
Abstract

BACKGROUND Since its outbreak in early 2020, the COVID-19 pandemic has diverted resources from non-urgent and elective procedures, leading to diagnosis and treatment delays, with an increased number of neoplasms at advanced stages worldwide. The aims of this study were to quantify the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic; and to evaluate whether delays in surgery led to an increased occurrence of aggressive tumours. METHODS In this retrospective, international, cross-sectional study, centres were invited to participate in June 22, 2022; each centre joining the study was asked to provide data from medical records on all surgical thyroidectomies consecutively performed from Jan 1, 2019, to Dec 31, 2021. Patients with indeterminate thyroid nodules were divided into three groups according to when they underwent surgery: from Jan 1, 2019, to Feb 29, 2020 (global prepandemic phase), from March 1, 2020, to May 31, 2021 (pandemic escalation phase), and from June 1 to Dec 31, 2021 (pandemic decrease phase). The main outcomes were, for each phase, the number of surgeries for indeterminate thyroid nodules, and in patients with a postoperative diagnosis of thyroid cancers, the occurrence of tumours larger than 10 mm, extrathyroidal extension, lymph node metastases, vascular invasion, distant metastases, and tumours at high risk of structural disease recurrence. Univariate analysis was used to compare the probability of aggressive thyroid features between the first and third study phases. The study was registered on ClinicalTrials.gov, NCT05178186. FINDINGS Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease were collected, of whom 22 974 patients (18 052 [78·6%] female patients and 4922 [21·4%] male patients) received surgery for indeterminate thyroid nodules. We observed a significant reduction in surgery for indeterminate thyroid nodules during the pandemic escalation phase (median monthly surgeries per centre, 1·4 [IQR 0·6-3·4]) compared with the prepandemic phase (2·0 [0·9-3·7]; p

Published
2023
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22. Gonioprobe, an innovative Gamma-probe to guide parathyroid radio-guided surgery: first clinical experiences with Navigator and Lock-on-target functions

Author

Bononi, Marco, primary, Viviana, Frantellizzi, additional, De Feo, Maria Silvia, additional, Sollaku, Saadi, additional, Pani, Arianna, additional, Falconi, Rita, additional, Pani, Roberto, additional, Cavallaro, Giuseppe, additional, Brozzetti, Stefania, additional, and De Vincentis, Giuseppe, additional

Published
2020
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24. Indications and results for transduodenal sphincteroplasty in the era of endoscopic sphincterotomy

Author

Miccini, Michelangelo, Bonapasta, Stefano Amore, Gregori, Matteo, Bononi, Marco, Fornasari, Vittorio, and Tocchi, Adriano

Subjects
Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjsurg.2009.08.048 Byline: Michelangelo Miccini, Stefano Amore Bonapasta, Matteo Gregori, Marco Bononi, Vittorio Fornasari, Adriano Tocchi Keywords: Oddi's papilla disorders; Sphincteroplasty; Surgical treatment Abstract: Transduodenal sphincterotomy (TS) has fallen into disuse since endoscopists developed techniques to treat sphincter problems nonsurgically. However, some patients experience recurrent sphincter strictures after endoscopic sphincterotomy (ES), with the ampulla endoscopically inaccessible, and pancreas divisum (PD); these patients are referred to a surgeon because they are unsuitable for ES. Author Affiliation: First Department of Surgery, Medical School, University of Rome 'Sapienza,' Viale del Policlinico 155, 00161 Rome, Italy Article History: Received 26 May 2009; Revised 22 July 2009

Published
2010

25. Expression and prognostic value of the cell polarity PAR complex members in thyroid cancer

Author

Tuccilli, Chiara, Baldini, Enke, Arlot Bonnemains, Yannick, Chesnel, Frank, Sorrenti, Salvatore, De Vito, Corrado, D'Armiento, Eleonora, Antonelli, Alessandro, Fallahi, Poupak, Watutantrige, Sara, Tartaglia, Francesco, Barollo, Susi, Mian, Caterina, Arcieri, Stefano, Mascagni, Domenico, Pironi, Daniele, Bononi, Marco, Vergine, Massimo, Monti, Massimo, Filippini, Angelo, Ulisse, Salvatore, WATUTANTRIGE FERNANDO, Sara, Department of Experimental Medicine, Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome] (UNIROMA), Department of Surgical Sciences, Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Department of Internal Medicine, University of Pisa - Università di Pisa, Department of Medical and Surgical Sciences, Università degli Studi di Padova = University of Padua (Unipd), Sapienza University of Rome [C26A14RNFY, C26N145E4T], Università degli Studi di Roma 'La Sapienza' = Sapienza University [Rome], Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Universita degli Studi di Padova, Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), and Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)

Subjects
0301 basic medicine, Cancer Research, medicine.medical_specialty, Cell, Anaplastic thyroid carcinoma, Apico-basal polarity, APKC, Papillary thyroid carcinoma, PAR complex, PARD3, PARD6, Thyroid, Biology, Apico-basal polarity, 03 medical and health sciences, Internal medicine, Cell polarity, Gene expression, medicine, Anaplastic thyroid carcinoma, APKC, Papillary thyroid carcinoma, PAR complex, PARD3, PARD6, Thyroid, Oncology, Thyroid cancer, [SDV.GEN]Life Sciences [q-bio]/Genetics, Oncogene, Cancer, Cell cycle, medicine.disease, Molecular medicine, 3. Good health, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Cancer research
Abstract

International audience; Establishment and maintenance of the apical basal cell polarity, required for proper replication, migration, specialized functions and tissue morphogenesis, relies on three evolutionary conserved complexes: PAR, CRUMBS and SCRIBBLE. Loss of cell polarity/cohesiveness (LOP/C) is implicated in cancer progression, and members of the polarity complex have been described as either oncogenes or oncosuppressors. However, no information on their role in thyroid cancer (TC) progression is available. In the present study, we evaluated the gene expression of the PAR complex members aPKCt, PARD3 alpha/beta and PARD6 alpha/beta/gamma in 95 papillary TC (PTC), compared to their normal matched tissues and in 12 anaplastic TC (ATC). The mRNA and protein levels of investigated genes were altered in the majority of PTC and ATC tissues. In PTC, univariate analysis showed that reduced expression of aPKCt, PARD3 beta and PARD6 gamma mRNAs is associated with increased tumor size, and the reduced expression of PARD3 beta mRNA is associated also with recurrences. Multivariate analysis demonstrated that the presence of lymph node metastasis at diagnosis and the reduced expression of PARD3 beta are independent risk factors for recurrences, with hazard ratio, respectively, of 8.21 (P=0.006) and 3.04 (P=0.029). The latter result was confirmed by the Kaplan-Meier analysis, which evidenced the association between decreased PARD3 beta mRNA levels and shorter disease-free interval. In conclusion, we demonstrated that the expression of PAR complex components is deregulated in the majority of PTC and there is a general trend towards their reduction in ATC tissues. Moreover, a prognostic value for the PARD3 beta gene in PTCs is suggested.

Published
2017

26. The THYCOVIT (Thyroid Surgery during COVID-19 pandemic in Italy) study: results from a nationwide, multicentric, case-controlled study.

Author

Medas, Fabio, Ansaldo, Gian Luca, Avenia, Nicola, Basili, Giancarlo, Boniardi, Marco, Bononi, Marco, Bove, Aldo, Carcoforo, Paolo, Casaril, Andrea, Cavallaro, Giuseppe, Chiofalo, Maria Grazia, Conzo, Giovanni, De Pasquale, Loredana, Del Rio, Paolo, Dionigi, Gianlorenzo, Dobrinja, Chiara, Docimo, Giovanni, Graceffa, Giuseppa, Iacobone, Maurizio, and Innaro, Nadia

Abstract

The outbreak of the COVID-19 pandemic has led to a disruption of surgical care. The aim of this multi-centric, retrospective study was to evaluate the impact of the pandemic on surgical activity for thyroid disease among the Italian Units of Endocrine Surgery. Three phases of the pandemic were identified based on the epidemiological situation and the public measures adopted from the Italian Government (1st phase: from 9th March to 3rd May 2020; 2nd phase: from 4th May to 14th June; 3rd phase: from 15th June to 31st). The patients operated upon during these phases were compared to those who underwent surgery during the same period of the previous year. Overall, 3892 patients from 28 Italian endocrine surgical units were included in the study, 1478 (38%) operated upon during COVID-19 pandemic, and 2414 (62%) during the corresponding period of 2019. The decrease in the number of operations was by 64.8%, 44.7% and 5.1% during the three phases of COVID-19 pandemic, compared to 2019, respectively. During the first and the second phases, the surgical activity was dedicated mainly to oncological patients. No differences in post-operative complications were noted between the two periods. Oncological activity for thyroid cancer was adequately maintained during the COVID-19 pandemic. [ABSTRACT FROM AUTHOR]

Published
2021
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27. Total Versus Completion Thyroidectomy: A Multidimensional Evaluation of Long-Term Vocal Alterations

Author

Minni, Antonio, Rosati, Davide, Cavaliere, Carlo, Ralli, Massimo, Sementilli, Giulio, Gallo, Andrea, Brozzetti, Stefania, Ossola, Paolo, Cavallaro, Giuseppe, and Bononi, Marco

Abstract

Background: Total thyroidectomy (TT) and completion thyroidectomy (CT) are two common surgical operations that are frequently followed by vocal symptoms despite preservation of the recurrent laryngeal nerve (RLN) and of the external branch of superior laryngeal nerve (EBSLN). The aim of this study was to analyze vocal alterations through endoscopic findings, videolaryngostroboscopy (VLS), acoustic vocal parameters and impact on patients’ quality of life after surgery in the absence of laryngeal nerve injury.Methods: We enrolled 198 patients who underwent thyroidectomy by the same surgeon. One hundred twenty-six patients underwent TT (group TT) while 72 underwent CT (group CT). All patients underwent preoperative VLS and Voice Handicap Index (VHI) assessment and postoperative VHI, VLS and Acoustic Voice Analysis with Multidimensional Voice Program Analysis 12 to 18 months after surgery.Results: We observed a statistically significant higher rate of EBSLN injury in CT compared to TT. Even in the absence of RLN and EBSLN injury, patients who underwent TT and CT presented slightly worse acoustic vocal parameters and VHI scores compared to healthy controls. Interestingly, some acoustic vocal parameters and VHI scores were significantly worse in group CT compared to group TT.Conclusions: The higher rate of EBSLN injury in CT rather than in TT suggests a higher surgical risk in CT. The vocal parameters of loudness and self-perception of voice were significantly worse after CT, suggesting a larger trauma in patients’ vocal outcome in CT if compared to TT, although these alterations were not reported as psychologically limiting daily life of patients. Nevertheless, the existence of multiple factors contributing to vocal alterations after thyroidectomy highlight the importance of a routine comprehensive functional voice analysis before and after surgery.

Published
2021
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28. Parathyroid Autotransplantation During thyroid Surgery. Where we are? A Systematic Review on Indications and Results.

Author

Iorio, Olga, Petrozza, Vincenzo, De Gori, Antonietta, Bononi, Marco, Porta, Natale, De Toma, Giorgio, and Cavallaro, Giuseppe

Subjects
AUTOTRANSPLANTATION, META-analysis, PARATHYROID glands, SURGERY, HYPOPARATHYROIDISM, THYROIDECTOMY
Abstract

Introduction: Hypoparathyroidism still represents an important concern in thyroid surgery. Careful dissection with identification and preservation of parathyroid glands in situ remains the best way to maintain gland vitality and avoid post-operative failure. Nevertheless, parathyroid glands are still inadvertently removed in up to 11% of cases. Parathyroid autotransplantation may represent the only way to restore parathyroid gland functionality in case of inadvertent removal or devascularization during thyroid surgery. Despite this, there is still no agreement on the effectiveness of this procedure. The present systematic review is focused on the mainly debated matters regarding the procedure, indications, technique and results. Methods: This review has been carried out according to PRISMA statement and checklist. The research item was: (((parathyroid autotransplantation[Title]) OR parathyroid reimplantation[Title]) NOT hyperparathyroidism[Title]) AND english[Language]. Results: A total of 31 studies have been found according to limitations already described, reporting from 4 to 890 procedures, with a total amount of 4088 PA. Among these studies, there are only 7 prospective case-series evaluations, 2 prospective randomized trials, while the other 22 studies are retrospective evaluations. The main concerns are: when and how to perform autotransplantation; in which anatomical site; which result to be expected, and how to manage and control the graft. Conslusions: Parathyroid autotransplantatin is an important tool to avoid or minimize the risk for hypoparathyroidism following thyroid surgery in selected cases. Parathormone assay can help the surgeon to determine when reimplantation is indicated or not. Further studies could theoretically give definitive results. [ABSTRACT FROM AUTHOR]

Published
2019
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30. Sonographic Presentation of Metastases to the Thyroid Gland: A Case Series

Author

Falcone, Rosa, primary, Ramundo, Valeria, additional, Lamartina, Livia, additional, Ascoli, Valeria, additional, Bosco, Daniela, additional, Di Gioia, Cira, additional, Montesano, Teresa, additional, Biffoni, Marco, additional, Bononi, Marco, additional, Giacomelli, Laura, additional, Minni, Antonio, additional, Segni, Maria, additional, Maranghi, Marianna, additional, Cantisani, Vito, additional, Durante, Cosimo, additional, and Grani, Giorgio, additional

Published
2018
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32. Gonioprobe, an Innovative Gamma-probe to Guide Parathyroid Radioguided Surgery: First Clinical Experiences with Navigator and Lock-ontarget Functions

Author

Bononi, Marco, Viviana, Frantellizzi, De Feo, Maria Silvia, Sollaku, Saadi, Pani, Arianna, Falconi, Rita, Pani, Roberto, Cavallaro, Giuseppe, Brozzetti, Stefania, and De Vincentis, Giuseppe

Abstract

Background: Radioguided surgery represents a validated technique for the detection and the excision of abnormal parathyroid glands responsible for primary hyperparathyroidism (PHPT). To date little attention has been paid as to how the characteristics of gamma-probes can influence surgical procedure and time, thus having an impact on postoperative morbidity, hospitalization and costs. Methods: We designed a new prototype of gamma-probe, the Gonioprobe, and tested its clinical utility in the operating room. Gonioprobe, thanks to its 5 scintillating independent crystals, performs the dual function of Navigator and Lock-on-target. These characteristics allow the immediate guidance of the surgeon’s hand towards the source with very high precision, and with a much higher spatial resolution than commercial probes. Gonioprobe was used during intervention to detect abnormal parathyroid tissue, and to ensure no radioactivity in surgery bed after adenoma removal. Results: We tested our gamma-probe on parathyroid adenomas particularly difficult to identify at a visual inspection due to anatomy modifications from previous neck surgery and/or characterized by uncommon localization. Moreover, parathyroid adenomas were hardly removable due to the proximity to the esophagus, neck vessels and/or recurrent laryngeal nerve (RLN). An intraoperative nerve monitoring system was used to protect the recurrent laryngeal nerve from injuries. Parathyroid hormone (PTH) assay and frozen biopsy confirmed the successful excision of the adenomas. Conclusion: The intraoperative use of the innovative Gonioprobe along with the nerve monitoring system allowed an accurate and safe removal of parathyroid adenomas and offered a significant advantage by reducing surgical time and postoperative complications, as well as hospitalization and costs.

Published
2021
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33. Deregulated expression of VHL mRNA variants in papillary thyroid cancer

Author

Baldini, Enke, primary, Tuccilli, Chiara, additional, Arlot-Bonnemains, Yannick, additional, Chesnel, Frank, additional, Sorrenti, Salvatore, additional, De Vito, Corrado, additional, Catania, Antonio, additional, D'Armiento, Eleonora, additional, Antonelli, Alessandro, additional, Fallahi, Poupak, additional, Watutantrige-Fernando, Sara, additional, Tartaglia, Francesco, additional, Barollo, Susi, additional, Mian, Caterina, additional, Bononi, Marco, additional, Arceri, Stefano, additional, Mascagni, Domenico, additional, Vergine, Massimo, additional, Pironi, Daniele, additional, Monti, Massimo, additional, Filippini, Angelo, additional, and Ulisse, Salvatore, additional

Published
2017
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34. [Hormone replacement therapy after total thyroidectomy. Can the combined treatment be considered effective to get metabolic adequacy? Preliminary results]

Author

Bononi, Marco, DE TOMA, Giorgio, Scarpini, Massimo, Miccini, Michelangelo, DE CESARE, Alessandro, Meucci, Massimo, AMORE BONAPASTA, Stefano, Celotto, A, and Tocchi, Adriano

Subjects
Adult, Male, Adolescent, Hormone Replacement Therapy, Middle Aged, Thyroid Diseases, Thyroxine, Treatment Outcome, Hypothyroidism, Thyroidectomy, Humans, Triiodothyronine, Drug Therapy, Combination, Female, Aged
Abstract

Even if T4 is standard treatment for hypothyroidism after thyroidectomy, a treatment with T4 plus T3 has been proposed as an alternative reproducing carefully the physiology of the thyroid. We performed an observational study about the effects of the combined replacement therapy with T4 and T3 in patients who underwent total thyroidectomy.Fifty thyroidectomized patients (not for cancer), in T4 replacement therapy, were included in the study. Such a therapy has been changed by administering T3 and T4 in proportion 1/16. Adverse effects, clinical parameters and general health perceptions (SF36 Questionnaire) have been considered at the time of enrollment (T0), after 30 days (T1) and after 60 days (T2).No differences in weight, cardiac frequency and blood pression have been found between T0 and T2. A not statistically significant reduction has been found in total cholesterol (3 mg/dL) and triglycerides (3.29 mg/dL) levels. A reduction of complaints referred by the patients at T0 has been revealed in T2: anxiety from 21 to 13 patients; headache from 22 to 13; tiredness from 17 to 8 (p0.05); sleepiness from 25 to 15 (p0.05). About the questionnaire, in the General Health Perception sub-score has been found a not significant increase of the parameter.T4 replacement therapy is of proved efficacy, notwithstanding some complaints afflict a share of patients. To improve the quality of life of these patients, we consider relevant the reduction of complaints and the improvement of well-being and cognitive function obtained by the combined T4 and T3 treatment. Moreover, even if the production of T3 from T4 usually ensures euthyroidism in all tissues, contemporary pathologies and alterations determined by the oldness can disturb the enzymatic activity, which is the essential requirement of T4 therapy. These preliminary findings in a small group of patients encourage further studies on a larger patient population.

Published
2010

37. Considerations

Author

Borghese, Ottavia, primary, Sapienza, Paolo, additional, Venturini, Luigi, additional, Bononi, Marco, additional, and di Marzo, Luca, additional

Published
2014
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45. Fine needle aspiration and core needle biopsy techniques in the diagnosis of nodular thyroid pathologies

Author

Tiziana, Pisani, Bononi, Marco, Nagar, C., Marta, Angelini, Bezzi, Mario, and Vecchione, Aldo

Subjects
Adenoma, Adult, Goiter, Biopsy, Needle, Reproducibility of Results, Middle Aged, core biopsy thyroid, fnab, thyroid nodules, Carcinoma, Papillary, Diagnosis, Differential, Adenocarcinoma, Follicular, Humans, Thyroid Neoplasms, Thyroid Nodule, False Negative Reactions, Aged, Ultrasonography
Abstract

It is widly accepted that Fine Needle Aspiration Biopsy (FNAB) is the main test to distinguish benign from malignant thyroid lesions. Nevertheless, this technique presents some limits such as the possibility of false-negative or inadequate samples and it is unable to cytologically discriminate among adenomathosus goiter, follicular adenoma and well-differentiated follicular carcinoma. The aim of this study was to evaluate the possibility of restricting these limitations using Core Needle biopsy (CN) technique. Therefore we selected for CN, 40 out of 136 patients who underwent FNAB during a one year period; among these patients only 32 agreed a to this technique. Forty-two out of 136 patients underwent surgery; 29 of them were subjected to both biopsies. Sixteen of the diagnostic microbiopsies have been histologically confirmed. We had no discordant cases between cytological and microhistological diagnosis, except for one case which appeared cytologically colloid goiter, microhistologically follicular neoplasm and histologically follicular adenoma. In this case it was not possible to microhistologically discriminate benign from malign follicular lesion. In our experience not all patients accepted CN biopsy as well as FNAB and, moreover, this technique showed no advantage over FNAB diagnosis. On this base we think that actually FNAB should be the main procedure in the diagnosis of the thyroid lesions. It is easily performed, accepted by the patients and has a low cost-benefit ratio. If the sample is not diagnostic it can be easily repeated and false-negative cases could be discovered thanks to an adequate clinical and ultrasonographical follow-up of the patients.

Published
2001

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