663 results on '"Borlak, Jürgen"'
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2. The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
3. Correction: A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence
4. Sex differences in the tumor promoting effects of tobacco smoke in a cRaf transgenic lung cancer disease model
5. Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary nonfunction of fatty liver allografts
6. A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence
7. Combined inhibition of histone deacetylase and cytidine deaminase improves epigenetic potency of decitabine in colorectal adenocarcinomas
8. Sex disparities in non-small cell lung cancer: mechanistic insights from a cRaf transgenic disease model
9. Genomics of human NAFLD: Lack of data reproducibility and high interpatient variability in drug target expression as major causes of drug failures.
10. Comprehensive transcriptome, miRNA and kinome profiling and its clinical translation for personalized lung cancer therapy
11. miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer
12. Advances in Liver Cancer Stem Cell Isolation and their Characterization
13. miR‐106b‐5p protects against drug‐induced liver injury by targeting vimentin to stimulate liver regeneration.
14. Predicting the Risks of Drug-Induced Liver Injury in Humans Utilizing Computational Modeling
15. Clinical validation of miRNA biomarkers to predict risk of primary non-function of fatty allografts following liver transplantation
16. An adverse outcome pathway for immune-mediated and allergic hepatitis: a case study with the NSAID diclofenac
17. The landscape of hepatobiliary adverse reactions across 53 herbal and dietary supplements reveals immune-mediated injury as a common cause of hepatitis
18. Treatment of cyclosporine induced hypertension: Results from a long-term observational study using different antihypertensive medications
19. Serum proteome mapping of EGF transgenic mice reveal mechanistic biomarkers of lung cancer precursor lesions with clinical significance for human adenocarcinomas
20. Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary nonfunction of fatty liver allografts
21. Cancer genomics predicts disease relapse and therapeutic response to neoadjuvant chemotherapy of hormone sensitive breast cancers
22. miR-106b-5p protects against drug-induced liver injury by targeting vimentin to stimulate liver regeneration
23. Supplementary Methods, Figures 1 - 4, Tables 1 - 2 from Targeted Inactivation of HDAC2 Restores p16INK4a Activity and Exerts Antitumor Effects on Human Gastric Cancer
24. Supplementary Figures S1-S3 from Cross-talk between Aryl Hydrocarbon Receptor and Mitogen-Activated Protein Kinase Signaling Pathway in Liver Cancer through c-raf Transcriptional Regulation
25. Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects
26. Genomics of human fatty liver disease reveal mechanistically linked lipid droplet–associated gene regulations in bland steatosis and nonalcoholic steatohepatitis
27. Mechanistic insight into sex differences in lung cancer induced by cRaf
28. A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescence
29. Diclofenac Disrupts the Circadian Clock and through Complex Cross-Talks Aggravates Immune-Mediated Liver Injury—A Repeated Dose Study in Minipigs for 28 Days
30. miR-106b-5p Stimulates Liver Regeneration and Protects Against Drug-Induced Liver Injury by Targeting Vimentin
31. Decoding Molecular Circuits of the Tumor Promoting Effects of Tobacco Smoke in a cRAF Transgenic Lung Cancer Disease Model
32. Drug-induced liver injury: Interactions between drug properties and host factors
33. Complement Depletion with Humanized Cobra Venom Factor in a Mouse Model of Age-Related Macular Degeneration
34. Isolation and cultivation of metabolically competent alveolar epithelial cells from A/J mice
35. How useful are clinical liver function tests in in vitro human hepatotoxicity assays?
36. A rat toxicogenomics study with the calcium sensitizer EMD82571 reveals a pleiotropic cause of teratogenicity
37. N‐acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury
38. Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease
39. Application of Kernel Method to Reveal Subtypes of TF Binding Motifs : Causal Analysis of Gene Expression Data
40. A Unifying Ontology to Integrate Histological and Clinical Observations for Drug-Induced Liver Injury
41. A unifying mathematical model of lipid droplet metabolism reveals key molecular players in the development of hepatic steatosis
42. Petasites for Migraine Prevention: New Data on Mode of Action, Pharmacology and Safety. A Narrative Review
43. Petasites for Migraine Prevention : New Data on Mode of Action, Pharmacology and Safety. A Narrative Review
44. A systematic comparison of hepatobiliary adverse drug reactions in FDA and EMA drug labeling reveals discrepancies
45. A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the ‘rule-of-two’ model
46. Reliable miRNA biomarker quantification in clinical practice – are we there yet?
47. Handbook of Toxicogenomics: A Strategic View of Current Research and Applications
48. Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1
49. Pathology of flupirtine-induced liver injury:: a histological and clinical study of six cases
50. Predicting idiosyncratic drug-induced liver injury – some recent advances
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