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Your search keyword '"Bortolazzi, F"' showing total 4 results
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4 results on '"Bortolazzi, F"'

2. Valutazione dell'effetto delle variabili socio-ambientali sul carico percepito dai familiari dei pazienti psicotici

Author

MAGLIANO, Lorenza, MALANGONE C, MARASCO C, ADINOLFI L, AGUGLIA V, AIROLDI D, ALETTI A, BENZI SL, BERTELLI M, BOINE G, BONDI E, BORTOLAZZI F, BRIGIDI E, CANGIANO C, CARNIANI A, CESANO S, CUCCINIELLO A, DEL VECCHIO B, DI FAZIO L, FAZI S, FEDERICI M, GRECO E, LACRIMINI G, LA DELFA E, LOMBARDI B, MARCONE G, MARTINO A, MODESTI V, NURRA M, PIEMONTESE G, POLETTI F, SAMBUCO A, SCUTO C, THEI P, TRISOLINI A, TULIGI F, ZANUS P, MAJ M., FIORILLO, Andrea, Magliano, Lorenza, Fiorillo, Andrea, Malangone, C, Marasco, C, Adinolfi, L, Aguglia, V, Airoldi, D, Aletti, A, Benzi, Sl, Bertelli, M, Boine, G, Bondi, E, Bortolazzi, F, Brigidi, E, Cangiano, C, Carniani, A, Cesano, S, Cucciniello, A, DEL VECCHIO, B, DI FAZIO, L, Fazi, S, Federici, M, Greco, E, Lacrimini, G, LA DELFA, E, Lombardi, B, Marcone, G, Martino, A, Modesti, V, Nurra, M, Piemontese, G, Poletti, F, Sambuco, A, Scuto, C, Thei, P, Trisolini, A, Tuligi, F, Zanus, P, and Maj, M.

Published
2000

3. Sviluppo di un questionario autocompilato per la valutazione delle opinioni dei familiari sulle cause e le conseguenze psicosociali della schizofrenia (QOF)

Author

MALANGONE C., FIORILLO, Andrea, GUARNERI M., MARASCO C., ADINOLFI, Luigi Elio, AGUGLIA V., AIROLDI D., BOINE G., BONDI E., BORTOLAZZI F., CARNIANI A., CUCCINIELLO A., DEL VECCHIO B., DI FAZIO L., LA DELFA E., LOMBARDI B., MARCONE G., PIEMONTESE G., POLETTI F., SAMBUCO A., TULIGI F., MAJ M., MAGLIANO, Lorenza, Malangone, C., Fiorillo, Andrea, Guarneri, M., Marasco, C., Magliano, Lorenza, Adinolfi, Luigi Elio, Aguglia, V., Airoldi, D., Boine, G., Bondi, E., Bortolazzi, F., Carniani, A., Cucciniello, A., DEL VECCHIO, B., DI FAZIO, L., LA DELFA, E., Lombardi, B., Marcone, G., Piemontese, G., Poletti, F., Sambuco, A., Tuligi, F., and Maj, M.

Published
2000

4. Induction of humoral and enhanced cellular immune responses by novel core-shell nanosphere- and microsphere-based vaccine formulations following systemic and mucosal administration.

Author

Caputo A, Castaldello A, Brocca-Cofano E, Voltan R, Bortolazzi F, Altavilla G, Sparnacci K, Laus M, Tondelli L, Gavioli R, and Ensoli B

Subjects
AIDS Vaccines administration & dosage, AIDS Vaccines immunology, Animals, Female, HIV Antibodies blood, Immunity, Mucosal, Immunization, Interferon-gamma biosynthesis, Interleukin-4 biosynthesis, Mice, Mice, Inbred BALB C, Microspheres, Nanospheres administration & dosage
Abstract

Anionic surfactant-free polymeric core-shell nanospheres and microspheres were previously described with an inner core constituted by poly(methylmethacrylate) (PMMA) and a highly hydrophilic outer shell composed of a hydrosoluble co-polymer (Eudragit L100-55). The outer shell is tightly linked to the core and bears carboxylic groups capable of adsorbing high amounts (antigen loading ability of up to 20%, w/w) of native basic proteins, mainly by electrostatic interactions, while preserving their activity. In the present study we have evaluated in mice the safety and immunogenicity of new vaccine formulations composed of these nano- and microspheres and the HIV-1 Tat protein. Vaccines were administered by different routes, including intramuscular, subcutaneous or intranasal and the results were compared to immunization with Tat alone or with Tat delivered with the alum adjuvant. The data demonstrate that the nano- and microspheres/Tat formulations are safe and induce robust and long-lasting cellular and humoral responses in mice after systemic and/or mucosal immunization. These delivery systems may have great potential for novel Tat protein-based vaccines against HIV-1 and hold promise for other protein-based vaccines.

Published
2009
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