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15. PSA et obésité: mythes et réalités

Author

Neuzillet, Y., primary, Dreyfus, J., additional, Rouanne, M., additional, Raynaud, J., additional, Schneider, M., additional, Rouprêt, M., additional, Drouin, S., additional, Galiano, M., additional, Cathelineau, X., additional, Lebret, T., additional, and Botto, H., additional

Published
2019
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27. Association entre l’agressivité histologique du cancer de la prostate localisé et les stéroïdes sexuel : résultats de l’étude ANDROCAN

Author

Neuzillet, Y., primary, Botto, H., additional, Schneider, M., additional, Rouprêt, M., additional, Drouin, S., additional, Galiano, M., additional, Cathelineau, X., additional, Taouil, T., additional, Molinie, V., additional, Radulescu, C., additional, Comperat, E., additional, Giton, F., additional, Fiet, J., additional, Raynaud, J., additional, and Lebret, T., additional

Published
2017
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28. Les profils hormonaux préopératoires et les caractéristiques pathologiques du cancer de la prostate localisé sont liés à la testostérone totale et biodisponible

Author

Neuzillet, Y., primary, Botto, H., additional, Schneider, M., additional, Rouprêt, M., additional, Drouin, S., additional, Galiano, M., additional, Cathelineau, X., additional, Taouil, T., additional, Molinie, V., additional, Radulescu, C., additional, Comperat, E., additional, Giton, F., additional, Fiet, J., additional, Raynaud, J., additional, and Lebret, T., additional

Published
2017
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33. [Foreign bodies in esophagus in children: case series]

Author

Rodríguez, H, Cuestas, G, Botto, H, Nieto, M, Cocciaglia, A, and Gregori, Dario

Subjects
Male, Esophagus, Adolescent, Child, Preschool, Humans, Infant, Female, Child, Foreign Bodies
Abstract

Ingestion of foreign bodies is an avoidable accident that is seen mainly in children under 3 years-old. Most of them pass through the digestive tract without causing clinical manifestations or complications, but a significant percentage is impacted in the esophagus causing vomiting, sore throat, dysphagia and drooling. The most common foreign bodies are coins. Complications usually occur when there is a delay in diagnosis or with large, sharp or potentially toxic objects, as the button battery. It is essential to make differential diagnosis between coin and button battery, since the latter requires urgent removal due to the earliness of the injury caused. We report 115 cases of foreign bodies in the esophagus, and we alert the pediatrician in recognizing and preventing this problem.

Published
2012

39. Chapter 11

Author

Johansen, Truls Erik B., Grabe, M, Bishop, MC, Botto, H, Cek, M, Lobel, B, Naber, KG, Palou, J, and Tenke, P

Published
2008

46. EAU guidelines for the management of urinary and male genital tract infections. Urinary Tract Infection (UTI) Working Group of the Health Care Office (HCO) of the European Association of Urology (EAU)

Author

Naber, K G, Bergman, B, Bishop, M C, Johansen, Truls Erik Berklund, Botto, H, Lobel, B, Jinenez Cruz, F, and Selvaggi, F P

Subjects
Male, Bacteriuria, Urethritis, Anti-Infective Agents, Urinary, Antibiotic Prophylaxis, Prostatitis, Diabetes Complications, Postmenopause, Pregnancy, Sepsis, Urinary Tract Infections, Humans, Female, Renal Insufficiency, Genital Diseases, Male, Child, Pyuria
Published
2001

47. Management of foreign bodies in the airway and oesophagus

Author

Rodríguez, H, Passali, Giulio Cesare, Gregori, D, Chinski, A, Tiscornia, C, Botto, H, Nieto, M, Zanetta, A, Passali, D, Cuestas, G., Passali, Giulio Cesare (ORCID:0000-0002-8176-0962), Rodríguez, H, Passali, Giulio Cesare, Gregori, D, Chinski, A, Tiscornia, C, Botto, H, Nieto, M, Zanetta, A, Passali, D, Cuestas, G., and Passali, Giulio Cesare (ORCID:0000-0002-8176-0962)

Abstract

Ingestion and/or aspiration of foreign bodies (FB) are avoidable incidents. Children between 1 and 3 years are common victims for many reasons: exploration of the environment through the mouth, lack of molars which decreases their ability to properly chew food, lack of cognitive capacity to distinguish between edible and inedible objects, and tendency to distraction and to perform other activities, like playing, whilst eating. Most FBs are expelled spontaneously, but a significant percentage impacts the upper aerodigestive tract. Approximately 80% of children's choking episodes are evaluated by pediatricians. The symptoms of aspiration or ingestion of FBs can simulate different paediatric diseases such as asthma, croup or pneumonia, delaying the correct diagnosis.

Published
2012

48. Effects of ρ-Da1a a peptidic α(1) (A) -adrenoceptor antagonist in human isolated prostatic adenoma and anaesthetized rats.

Author

Palea S, Maiga A, Guilloteau V, Rekik M, Guérard M, Rouget C, Rischmann P, Botto H, Camparo P, Lluel P, Gilles N, Palea, S, Maiga, A, Guilloteau, V, Rekik, M, Guérard, M, Rouget, C, Rischmann, P, Botto, H, and Camparo, P

Abstract

Background and Purpose: ρ-Da1a, a 65 amino-acid peptide, has subnanomolar affinity and high selectivity for the human α(1) (A) -adrenoceptor subtype. The purpose of this study was to characterize the pharmacological effects of ρ-Da1a on prostatic function, both in vivo and in vitro.Experimental Approach: ρ-Da1a was tested as an antagonist of adrenaline-induced effects on COS cells transfected with the human α(1) (A) -adrenoceptor as well as on human isolated prostatic adenoma obtained from patients suffering from benign prostatic hyperplasia. Moreover, we compared the effects of ρ-Da1a and tamsulosin on phenylephrine (PHE)-induced increases in intra-urethral (IUP) and arterial pressures (AP) in anaesthetized rats, following i.v. or p.o. administration.Key Results: On COS cells expressing human α(1) (A) -adrenoceptors and on human prostatic strips, ρ-Da1a inhibited adrenaline- and noradrenaline-induced effects. In anaesthetized rats, ρ-Da1a and tamsulosin administered i.v. 30 min before PHE significantly antagonized the effects of PHE on IUP. The pK(B) values for tamsulosin and ρ-Da1a for this effect were similar. With regards to AP, ρ-Da1a only reduced the effect of PHE on AP at the lowest dose tested (10 μg·kg(-1) ), whereas tamsulosin significantly reduced PHE effects at doses between 10 and 150 μg·kg(-1) .Conclusions and Implications: ρ-Da1a exhibited a relevant effect on IUP and a small effect on AP. In contrast, tamsulosin antagonized the effects of PHE on both IUP and AP. We conclude that ρ-Da1a is more uroselective than tamsulosin. ρ-Da1a is the most selective peptidic antagonist for α(1A) -adenoceptors identified to date and could be a new treatment for various urological diseases. [ABSTRACT FROM AUTHOR]

Published
2013
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