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10 results on '"Boue-Vaysse, C."'

3. Un régime hyperlipidique/hypercalorique réduit la synthèse protéique musculaire chez le rat âgé : implication de l’insulino-résistance, de la lipotoxicité et de l’inflammation

Author

Salles, Jérôme, Tardif, Nicolas, Guillet, Christelle, Landrier, Jean-Francois, Mothe-Satney, I., Boue-Vaysse, C., Giraudet, Christophe, Patrac, Véronique, Bertrand-Michel, J., Chardigny, Jean-Michel, Boirie, Yves, Walrand, Stéphane, Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université, Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Dysfonctions métaboliques et diabètes: Mécanismes et approches thérapeutiques, Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-IFR50-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut des corps gras (ITERG), Centre de Physiopathologie Toulouse Purpan ex IFR 30 et IFR 150 (CPTP), Université Toulouse III - Paul Sabatier (UT3), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV]Life Sciences [q-bio]
Published
2012

4. Differential impact of milk fatty acid profiles on cardiovascular risk biomarkers in healthy men and women

Author

Boue-Vaysse C, Mouriot J, Béatrice Morio, J.L. Peyraud, Jean Michel Chardigny, Nicole Combe, Corinne Malpuech-Brugère, P. Leruyet, G. Chesneau, Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Clermont Université, ANR-Agence Nationale de la Recherche - The French National Research Agency (ANR-05-PNRA 5.E.24), and Clermont Université-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Recherche Agronomique (INRA)

Subjects
Male, cardiovascular risk factors, Calorie, 030309 nutrition & dietetics, [SDV]Life Sciences [q-bio], Medicine (miscellaneous), 030204 cardiovascular system & hematology, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, 2. Zero hunger, chemistry.chemical_classification, 0303 health sciences, Nutrition and Dietetics, milk fat, Fatty Acids, food and beverages, Middle Aged, Lipids, Milk, Cardiovascular Diseases, Female, trans fatty acids, Vitamin, Adult, medicine.medical_specialty, Adolescent, 03 medical and health sciences, Young Adult, Animal science, Double-Blind Method, Internal medicine, medicine, Animals, Humans, [INFO]Computer Science [cs], Risk factor, Nutrition, Cholesterol, business.industry, Fatty acid, cholesterol, medicine.disease, Obesity, Dietary Fats, Endocrinology, Human nutrition, chemistry, Cattle, Dairy Products, business, Biomarkers, Lipoprotein
Abstract

The objective of this study was to evaluate the impact of three specific ruminant (R) milk fats resulting from modification of the cow's diet on cardiovascular risk factors in healthy volunteers. R-milk fats were characterized by increased content in total trans fatty acids (R-TFAs) and parallel decrease in saturated fatty acids (SFAs).A total of 111 healthy, normolipemic men and women have been recruited for a monocentric, randomized, double-blind and parallel intervention, 4-week controlled study. Volunteers consumed three experimental products (butter, dessert cream and cookies) made with one of the three specific milk fats (55 g fat per day). During the first week (run-in period), the subjects consumed on a daily basis dairy products containing 72% SFA/2.85% R-TFA (called 'L0'). For the next 3 weeks of the study (intervention period), the first group continued to consume L0 products. The second group received dairy products containing 63.3% SFA/4.06% R-TFA (called 'L4'), and the third group received dairy products containing 56.6% SFA/12.16% R-TFA (called 'L9').Plasma concentrations of high-density lipoprotein (HDL)-cholesterol were not significantly altered by either diet (P=0.38). Compared to L0 diet, L4 diet contributed to reduce low-density lipoprotein (LDL)-cholesterol (-0.14+/-0.38 mmol/l, P=0.04), total cholesterol (-0.13+/-0.50 mmol/l, P=0.04), LDL-cholesterol/HDL-cholesterol (-0.14+/-0.36, P=0.03) and total cholesterol/HDL-cholesterol (-0.18+/-0.44, P=0.02).Different milk fat profiles can change cardiovascular plasma parameters in human healthy volunteers. A limited increase of the R-TFA/SFA ratio in dairy products is associated with an improvement in some cardiovascular risk factors. However, a further increase in R-TFA/SFA ratio has no additional benefit.

Published
2010
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5. N-3 fatty acids affected glial morphometry during aging in fat-1 mice

Author

Joffre, Corinne, Costes, Laurence, Lalanne, J., Boue-Vaysse, C., Buaud, B., Layé, Sophie, Psychoneuroimmunologie, nutrition et génétique, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS), and Institut des corps gras (ITERG)

Subjects
[SDV]Life Sciences [q-bio], ComputingMethodologies_GENERAL, ComputingMilieux_MISCELLANEOUS
Abstract

Poster n°491; International audience

Published
2009

6. PO33 Un régime hyperlipidique/hypercalorique réduit la synthèse protéique musculaire chez le rat âgé : implication de l’insulino-résistance, de la lipotoxicité et de l’inflammation

Author

Salles, J., primary, Tardif, N., additional, Guillet, C., additional, Landrier, J.F., additional, Mothe-Satney, I., additional, Boue-Vaysse, C., additional, Giraudet, C., additional, Patrac, V., additional, Bertrand-Michel, J., additional, Chardigny, J.M., additional, Boirie, Y., additional, and Walrand, S., additional

Published
2012
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10. Oleate-enriched diet improves insulin sensitivity and restores muscle protein synthesis in old rats.

Author

Tardif N, Salles J, Landrier JF, Mothe-Satney I, Guillet C, Boue-Vaysse C, Combaret L, Giraudet C, Patrac V, Bertrand-Michel J, Migné C, Chardigny JM, Boirie Y, and Walrand S

Subjects
Acyl-CoA Dehydrogenase biosynthesis, Acyl-CoA Dehydrogenase genetics, Adipose Tissue metabolism, Age Factors, Animals, Carnitine O-Palmitoyltransferase biosynthesis, Carnitine O-Palmitoyltransferase genetics, Interleukin-1beta metabolism, Male, Peroxisome Proliferator-Activated Receptors biosynthesis, Peroxisome Proliferator-Activated Receptors genetics, RNA, Messenger chemistry, RNA, Messenger genetics, Random Allocation, Rats, Rats, Wistar, Reverse Transcriptase Polymerase Chain Reaction, Tumor Necrosis Factor-alpha metabolism, Insulin Resistance, Muscle Proteins metabolism, Muscle, Skeletal metabolism, Oleic Acid administration & dosage
Abstract

Background & Aims: Age-related inflammation and insulin resistance (IR) have been implicated in the inability of old muscles to properly respond to anabolic stimuli such as amino acids (AA) or insulin. Since fatty acids can modulate inflammation and IR in muscle cells, we investigated the effect of palmitate-enriched diet and oleate-enriched diet on inflammation, IR and muscle protein synthesis (MPS) rate in old rats., Methods: Twenty-four 25-month-old rats were fed either a control diet (OC), an oleate-enriched diet (HFO) or a palmitate-enriched diet (HFP) for 16 weeks. MPS using labeled amino acids and mTOR activation were assessed after AA and insulin anabolic stimulation to mimic postprandial state., Results: IR and systemic and adipose tissue inflammation (TNFα and IL1β) were improved in the HFO group. Muscle genes controlling mitochondrial β-oxidation (PPARs, MCAD and CPT-1b) were up-regulated in the HFO group. AA and insulin-stimulated MPS in the HFO group only, and this stimulation was related to activation of the Akt/mTOR pathway., Conclusions: The age-related MPS response to anabolic signals was improved in rats fed an oleate-enriched diet. This effect was related to activation of muscle oxidative pathways, lower IR, and a decrease in inflammation., (2011 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.)

Published
2011
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