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183 results on '"Boull, Christina"'

1. Mucocutaneous toxicities from MEK inhibitors: a scoping review of the literature

Author

Iriarte, Christopher, Yeh, Jennifer E., Alloo, Allireza, Boull, Christina, Carlberg, Valerie M., Coughlin, Carrie C., Lara-Corrales, Irene, Levy, Rebecca, Nguyen, Cuong V., Oza, Vikash S., Patel, Anisha B., Rotemberg, Veronica, Shah, Sonal D., Zheng, Lida, Miller, Corinne H., Hlobik, Madeline, Daigneault, Jaclyn, Choi, Jennifer N., Huang, Jennifer T., and Vivar, Karina L.

Published
2024
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4. Surgery in Dermatology

Author

Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, Boull, Christina, Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, and Boull, Christina

Published
2021
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5. Cosmetic Dermatology

Author

Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, Boull, Christina, Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, and Boull, Christina

Published
2021
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6. Pharmacotherapy

Author

Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, Boull, Christina, Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, and Boull, Christina

Published
2021
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7. Pediatric Dermatology

Author

Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, Boull, Christina, Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, and Boull, Christina

Published
2021
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8. General Dermatology

Author

Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, Boull, Christina, Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, and Boull, Christina

Published
2021
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9. Anatomy

Author

Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, Boull, Christina, Hylwa, Sara, Hurliman, Elisabeth, Liu, Jing, Luxenberg, Erin, and Boull, Christina

Published
2021
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16. Improvement in Atopic Dermatitis and Recurrent Infection With Dupilumab in Children With Distinct Genetic Types of Hyper‐IgE Syndrome: A Case Series and Literature Review.

Author

Dick, Jenna K., Boull, Christina, Pozos, Tamara C., and Maguiness, Sheilagh M.

Subjects
*ATOPIC dermatitis, *GENETIC disorders, *DISEASE relapse, *LUNG infections, *CHILD patients
Abstract

ABSTRACT Hyperimmunoglobulin E syndrome (HIES) is a group of rare genetic disorders characterized by severe atopic dermatitis and recurrent skin and pulmonary infections. The efficacy of dupilumab in pediatric patients with HIES‐associated severe atopic dermatitis is relatively understudied. Here, we present a series of three children with HIES, two with AD‐HIES caused by STAT3 mutations, and one with AR‐HIES caused by biallelic mutations in ZNF341. In all cases, dupilumab treatment led to sustained clearance of severe atopic dermatitis over multiple years, as well as improvements in systemic symptoms of HIES. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Pocket Dermatology

Author

Hylwa, Sara, primary, Hurliman, Elisabeth, additional, Liu, Jing, additional, Luxenberg, Erin, additional, and Boull, Christina, additional

Published
2021
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21. Stigmatization and Mental Health Impact of Chronic Pediatric Skin Disorders

Author

Paller, Amy S., Rangel, Stephanie M., Chamlin, Sarah L., Hajek, Aleena, Phan, Sheshanna, Hogeling, Marcia, Castelo-Soccio, Leslie, Lara-Corrales, Irene, Arkin, Lisa, Lawley, Leslie P., Funk, Tracy, Castro Porto Silva Lopes, Fabiana, Antaya, Richard J., Ramien, Michele L., Vivar, Karina L., Teng, Joyce, Coughlin, Carrie C., Rehmus, Wingfield, Gupta, Deepti, Bercovitch, Lionel, Stein, Sarah L., Boull, Christina, Tom, Wynnis L., Liang, Marilyn G., Hunt, Raegan, Luu, Minnelly, Holland, Kristen E., Schoch, Jennifer J., Cella, David, Lai, Jin-Shei, and Griffith, James W.

Abstract

IMPORTANCE: Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic skin disease and association with mental health needs further study. OBJECTIVE: To examine the extent of stigma, dependence on disease visibility and severity, and association with mental health and quality of life (QOL) in chronic pediatric skin disease. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional, single-visit study was conducted at 32 pediatric dermatology centers in the US and Canada from November 14, 2018, to November 17, 2021. Participants included patients aged 8 to 17 years with chronic skin disease and 1 parent. MAIN OUTCOMES AND MEASURES: Using the Patient-Reported Outcomes Measurement Instrumentation System (PROMIS) Stigma-Skin, the extent of stigma with child-, caregiver-, and physician-assessed disease visibility (primary outcome) and severity was compared, as well as reduced QOL (assessed by Skindex-Teen), depression, anxiety, and poor peer relationships (PROMIS child and proxy tools) (secondary outcomes). RESULTS: The study included 1671 children (57.9% female; mean [SD] age, 13.7 [2.7] years). A total of 56.4% participants had self-reported high disease visibility and 50.5% had moderate disease severity. Stigma scores significantly differed by level of physician-assessed and child/proxy-assessed disease visibility and severity. Among children with chronic skin disorders, predominantly acne, atopic dermatitis, alopecia areata, and vitiligo, only 27.0% had T scores less than 40 (minimal or no stigma) and 43.8% had at least moderate stigma (T score ≥45) compared with children with a range of chronic diseases. Stigma scores correlated strongly with reduced QOL (Spearman ρ = 0.73), depression (ρ = 0.61), anxiety (ρ = 0.54), and poor peer relationships (ρ = −0.49). Overall, 29.4% of parents were aware of bullying of their child, which was strongly associated with stigma (Cohen d = −0.79, with children who were not bullied experiencing lower levels of stigma). Girls reported more stigma than boys (Cohen d = 0.26). Children with hyperhidrosis and hidradenitis suppurativa were most likely to have increased depression and anxiety. CONCLUSIONS AND RELEVANCE: The findings of this study suggest that physician assessment of disease severity and visibility is insufficient to evaluate the disease impact in the patient/caregiver. Identifying stigmatization, including bullying, and tracking improvement through medical and psychosocial interventions may be a key role for practitioners.

Published
2024
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22. Arteriovenous malformations as a presenting sign of PTEN hamartoma tumor syndrome: A case series.

Author

Dykman, Morgan, Pillai, Nishitha R., Lenhart, Kelsey, Nicholson, Cynthia, Boull, Christina, Fritz, Erin, Flanagan, Siobhan, and Maguiness, Sheilagh

Subjects
HEREDITARY hemorrhagic telangiectasia, ARTERIOVENOUS malformation, PTEN protein, HAMARTOMA, DELAYED diagnosis, SYNDROMES
Abstract

High‐flow vascular malformations have been associated with multiple syndromes including capillary malformation–arteriovenous malformation (CM–AVM) syndrome, hereditary hemorrhagic telangiectasia syndrome, and less commonly, phosphatase and tensin homolog hamartoma tumor syndrome (PHTS). We present a series of three patients with clinically challenging complex AVMs who were found to have underlying PHTS. In all patients, diagnosis was delayed, and the presence of the AVM prompted sampling and genetic testing for PHTS in the absence of other clinical features of the condition. This series highlights the importance of screening for PHTS in the setting of high‐flow vascular malformations. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Transition of care in patients with epidermolysis bullosa: A survey study.

Author

Han, Joohee, Dykman, Morgan, Lunos, Scott, Nguyen, Audrey, Hook, Kristen P., Lara‐Corrales, Irene, Price, Harper N., Diaz, Lucia, Levy, Moise, and Boull, Christina

Subjects
EPIDERMOLYSIS bullosa, MEDICAL personnel, PEDIATRIC dermatology, PEDIATRIC therapy
Abstract

There are little published data on the transition of care in EB. We conducted a survey study recruiting EB patients from the Dystrophic EB Research Association (debra) website and centers caring for high numbers of EB patients in the United States and internationally from Sept 17, 2019 to Nov 3, 2021. The majority of participants had not discussed the transition of care with their healthcare providers, nor the healthcare needs to be required as an adult. Ongoing pediatric subspecialty care was reported by 12% of adults, most commonly in pediatric dermatology. Identified barriers to transition included the perceived lack of adult providers' knowledge about EB patient healthcare needs. The results suggest the need for transition guidelines, early discussions with families about transition, and practical information for the adult providers accepting care. [ABSTRACT FROM AUTHOR]

Published
2023
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