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1. A Transcriptomic Comparative Study of Cranial Vasculature

Author

Zhang, Jianing, Ryu, Jee-Yeon, Tirado, Selena-Rae, Dickinson, Lawrence D., Abosch, Aviva, Aziz-Sultan, M. Ali, Boulos, Alan S., Barrow, Daniel L., Batjer, H. Hunt, Binyamin, Tamar R., Blackburn, Spiros L., Chang, Edward F., Chen, P. Roc, Colby, Geoffrey P., Cosgrove, G. Rees, David, Carlos A., Day, Arthur L., Folkerth, Rebecca D., Frerichs, Kai U., Howard, Brian M., Jahromi, Behnam R., Niemela, Mika, Ojemann, Steven G., Patel, Nirav J., Richardson, R. Mark, Shi, Xiangen, Valle-Giler, Edison P., Wang, Anthony C., Welch, Babu G., Williams, Ziv, Zusman, Edie E., Weiss, Scott T., and Du, Rose

Published
2024
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2. Somatic Variants in SVIL in Cerebral Aneurysms

Author

Lai, Pui Man Rosalind, Ryu, Jee-Yeon, Park, Sang-Cheol, Gross, Bradley A, Dickinson, Lawrence D, Dagen, Sarajune, Aziz-Sultan, Mohammad Ali, Boulos, Alan S, Barrow, Daniel L, Batjer, H Hunt, Blackburn, Spiros, Chang, Edward F, Chen, P Roc, Colby, Geoffrey P, Cosgrove, Garth Rees, David, Carlos A, Day, Arthur L, Frerichs, Kai U, Niemela, Mika, Ojemann, Steven G, Patel, Nirav J, Shi, Xiangen, Valle-Giler, Edison P, Wang, Anthony C, Welch, Babu G, Zusman, Edie E, Weiss, Scott T, and Du, Rose

Subjects
Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Genetics, Biological Sciences, Brain Disorders, Biotechnology, Cardiovascular, Stroke, Neurosciences, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Clinical sciences
Abstract

Background and objectivesWhile somatic mutations have been well-studied in cancer, their roles in other complex traits are much less understood. Our goal is to identify somatic variants that may contribute to the formation of saccular cerebral aneurysms.MethodsWe performed whole-exome sequencing on aneurysm tissues and paired peripheral blood. RNA sequencing and the CRISPR/Cas9 system were then used to perform functional validation of our results.ResultsSomatic variants involved in supervillin (SVIL) or its regulation were found in 17% of aneurysm tissues. In the presence of a mutation in the SVIL gene, the expression level of SVIL was downregulated in the aneurysm tissue compared with normal control vessels. Downstream signaling pathways that were induced by knockdown of SVIL via the CRISPR/Cas9 system in vascular smooth muscle cells (vSMCs) were determined by evaluating changes in gene expression and protein kinase phosphorylation. We found that SVIL regulated the phenotypic modulation of vSMCs to the synthetic phenotype via Krüppel-like factor 4 and platelet-derived growth factor and affected cell migration of vSMCs via the RhoA/ROCK pathway.DiscussionWe propose that somatic variants form a novel mechanism for the development of cerebral aneurysms. Specifically, somatic variants in SVIL result in the phenotypic modulation of vSMCs, which increases the susceptibility to aneurysm formation. This finding suggests a new avenue for the therapeutic intervention and prevention of cerebral aneurysms.

Published
2022

3. Safety and efficacy results of the Flow Redirection Endoluminal Device (FRED) stent system in the treatment of intracranial aneurysms: US pivotal trial.

Author

McDougall, Cameron G, Diaz, Orlando, Boulos, Alan, Siddiqui, Adnan H, Caplan, Justin, Fifi, Johanna T, Turk, Aquilla S, Kayan, Yasha, Jabbour, Pascal, Kim, Louis J, Hetts, Steven W, Cooke, Daniel L, and Dowd, Christopher F

Subjects
Humans, Intracranial Aneurysm, Treatment Outcome, Embolization, Therapeutic, Prospective Studies, Stents, Stroke, Endovascular Procedures, aneurysm, flow diverter, intervention, technology, Comparative Effectiveness Research, Neurosciences, Clinical Research, Clinical Trials and Supportive Activities, Bioengineering, Cardiovascular
Abstract

ObjectiveTo evaluate the safety and effectiveness of the Flow Redirection Endoluminal Device (FRED) flow diverter in support of an application for Food and Drug Administration approval in the USA.Methods145 patients were enrolled in a prospective, single-arm multicenter trial. Patients with aneurysms of unfavorable morphology for traditional endovascular therapies (large, wide-necked, fusiform, etc) were included. The trial was designed to demonstrate non-inferiority in both safety and effectiveness, comparing trial results with performance goals (PGs) established from peer-reviewed published literature. The primary safety endpoint was death or major stroke (National Institutes of Health Stroke Scale score ≥4 points) within 30 days of the procedure, or any major ipsilateral stroke or neurological death within the first year. The primary effectiveness endpoint was complete occlusion of the target aneurysm with ≤50% stenosis of the parent artery at 12 months after treatment, and in which an alternative treatment of the target intracranial aneurysm had not been performed.Results145 patients underwent attempted placement of a FRED device, and one or more devices were placed in all 145 patients. 135/145 (93%) had a single device placed. Core laboratory adjudication deemed 106 (73.1%) of the aneurysms large or giant. A safety endpoint was experienced by 9/145 (6.2%) patients, successfully achieving the safety PG of 46% aneurysm occlusion was also achieved, with the effectiveness endpoint being met in 80/139 (57.6%) CONCLUSION: As compared with historically derived performance benchmarks, the FRED flow diverter is both safe and effective for the treatment of appropriately selected intracranial aneurysms.Clinical registration numberNCT01801007.

Published
2022

4. Rationale and Design for the BLOCK-SAH Study (Pterygopalatine Fossa Block as an Opioid-Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage): A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial with a Sequential Parallel Comparison Design

Author

Busl, Katharina M., Smith, Cameron R., Troxel, Andrea B., Fava, Maurizio, Illenberger, Nicholas, Pop, Ralisa, Yang, Wenqing, Frota, Luciola Martins, Gao, Hanzhi, Shan, Guogen, Hoh, Brian L., Maciel, Carolina B., Boulos, Alan, Laufer, Andras, Argoff, Charles E., Figueroa, Christopher, Barnes, Erin, Lee, James, Sheikh, Mahtab, and Bughrara, Nibras

Subjects
CLINICAL trials, SALINE solutions, PAIN management, NERVE block, SUBARACHNOID hemorrhage
Abstract

Background: Acute post-subarachnoid hemorrhage (SAH) headaches are common and severe. Management strategies for post-SAH headaches are limited, with heavy reliance on opioids, and pain control is overall poor. Pterygopalatine fossa (PPF) nerve blocks have shown promising results in treatment of acute headache, including our preliminary and published experience with PPF-blocks for refractory post-SAH headache during hospitalization. The BLOCK-SAH trial was designed to assess the efficacy and safety of bilateral PPF-blocks in awake patients with severe headaches from aneurysmal SAH who require opioids for pain control and are able to verbalize pain scores. Methods: BLOCK-SAH is a phase II, multicenter, randomized, double-blinded, placebo-controlled clinical trial using the sequential parallel comparison design (SPCD), followed by an open-label phase. Results: Across 12 sites in the United States, 195 eligible study participants will be randomized into three groups to receive bilateral active or placebo PPF-injections for 2 consecutive days with periprocedural monitoring of intracranial arterial mean flow velocities with transcranial Doppler, according to SPCD (group 1: active block followed by placebo; group 2: placebo followed by active block; group 3: placebo followed by placebo). PPF-injections will be delivered under ultrasound guidance and will comprise 5-mL injectates of 20 mg of ropivacaine plus 4 mg of dexamethasone (active PPF-block) or saline solution (placebo PPF-injection). Conclusions: The trial has a primary efficacy end point (oral morphine equivalent/day use within 24 h after each PPF-injection), a primary safety end point (incidence of radiographic vasospasm at 48 h from first PPF-injection), and a primary tolerability end point (rate of acceptance of second PPF-injection following the first PPF-injection). BLOCK-SAH will inform the design of a phase III trial to establish the efficacy of PPF-block, accounting for different headache phenotypes. [ABSTRACT FROM AUTHOR]

Published
2025
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5. Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke)

Author

Froehler, Michael T, Saver, Jeffrey L, Zaidat, Osama O, Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P, Haussen, Diogo C, Hellinger, Frank R, Yavagal, Dileep R, Yao, Tom L, Liebeskind, David S, Jadhav, Ashutosh P, Gupta, Rishi, Hassan, Ameer E, Martin, Coleman O, Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G, Gandhi, Ravi H, Peterson, Eric C, Dashti, Shervin R, Given, Curtis A, Mehta, Brijesh P, Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H, Kvamme, Peter, Grobelny, Thomas J, Hussain, Muhammad S, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J, Ecker, Robert D, Schirmer, Clemens M, Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P, Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H, Dumont, Travis M, Alhajeri, Abdulnasser, Taqi, M Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S, Chitale, Rohan, Deshaies, Eric M, Robinson, David H, Kallmes, David F, Baxter, Blaise W, Jumaa, Mouhammad A, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D, Suzuki, Shuichi, Fessler, Richard D, Almandoz, Josser E Delgado, Martin, Jerry C, and Mueller-Kronast, Nils H

Subjects
Stroke, Clinical Research, Brain Disorders, Endovascular Procedures, Hospitals, Humans, Ischemia, Patient Transfer, Prospective Studies, Registries, Survival Analysis, Thrombectomy, Time Factors, Treatment Outcome, emergency medical services, endovascular treatment, ischemic stroke, stent retriever, systems of care, STRATIS Investigators, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology
Abstract

BackgroundEndovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.MethodsSTRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or without intravenous tissue plasminogen activator and were admitted to endovascular-capable centers via either interhospital transfer or direct presentation. The primary clinical outcome was functional independence (modified Rankin Score 0-2) at 90 days. We assessed (1) real-world time metrics of stroke care delivery, (2) outcome differences between direct and transfer patients undergoing MT, and (3) the potential impact of local hospital bypass.ResultsA total of 984 patients were analyzed. Median onset-to-revascularization time was 202.0 minutes for direct versus 311.5 minutes for transfer patients (P

Published
2017

6. 692 Impact of Dual Antiplatelet Therapy After Stent-assisted Coiling of Unruptured Aneurysms on Risk of Complications

Author

Ringer, Andrew J., primary, Hanel, Ricardo, additional, Baig, Ammad, additional, Siddiqui, Adnan Hussain, additional, Lopes, Demetrius K., additional, Levitt, Michael Robert, additional, Naylor, Ryan M., additional, Lanzino, Giuseppe, additional, Crowley, R. Webster, additional, Serrone, Joseph, additional, Kan, Peter T., additional, Binning, Mandy Jo, additional, Veznedaroglu, Erol, additional, Boulos, Alan S., additional, and Tawk, Rabih G., additional

Published
2024
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9. Developing a fast-track discharge protocol for patients with cerebral aneurysms treated via neuroendovascular techniques.

Author

Entezami, Pouya, Rock, Andrew K., Topp, Gregory P., Heydari, Ehsaun S., Field, Nicholas C., Boulos, Alan S., Dalfino, John C., Yamamoto, Junichi, Pilitsis, Julie G., Cherukupalli, Divya, McCallum, Sarah E., and Paul, Alexandra R.

Subjects
INTRACRANIAL aneurysms, HOSPITAL admission & discharge, HOSPITAL utilization, LOGISTIC regression analysis, PATIENT readmissions, THERAPEUTIC embolization
Abstract

Introduction: As we emerge from the current pandemic, hospitals, staff, and resources will need to continue to adjust to meet ongoing healthcare demands. Lessons learned during past shortages can be used to optimize peri-procedural protocols to safely improve the utilization of hospital resources. Methods: Retrospective review of patients who underwent elective endovascular intracranial aneurysm treatment was performed. Multivariable logistic regression was used to identify factors associated with patients who were able to be discharged within 24 h of elective procedures. Rates of complications (particularly readmission) were determined. Results: 330 patients underwent elective endovascular aneurysm treatment with 86 (26.1%) discharged within 24 h. Factors associated with earlier discharge included procedure years (2019–2021) and male sex. Patients were more likely to be discharged later (after 24 h) if they underwent stent-coil embolization or flow-diversion. There was no association between discharge timing and likelihood of readmission. Discussion: Our review highlights the safety of earlier discharge and allowed us to prepare a fast-track protocol for same-day discharge in these patients. This protocol will be studied prospectively in the next phase of this study. As we gain more comfort with emerging, minimally invasive endovascular therapies, we hope to safely achieve same-day discharge on a protocolized and routine basis, reducing the demand of elective aneurysm treatments on our healthcare system. Conclusion: We retrospectively demonstrate that early discharge following elective aneurysm treatment is safe in our cohort and provide a fast-track pathway based on these findings for other centers developing similar protocols. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Unruptured Intracranial Aneurysms

Author

Deshaies, Eric M., Singla, Amit, Gandhi, Ravi H., Boulos, Alan S., Tarsy, Daniel, Series editor, Edgell, Randall C., editor, Savitz, Sean I., editor, and Dalfino, John, editor

Published
2015
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14. Impact of Balloon Guide Catheter Use on Clinical and Angiographic Outcomes in the STRATIS Stroke Thrombectomy Registry

Author

Zaidat, Osama O., Mueller-Kronast, Nils H., Hassan, Ameer E., Haussen, Diogo C., Jadhav, Ashutosh P., Froehler, Michael T., Jahan, Reza, Ali Aziz-Sultan, Mohammad, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Gupta, Rishi, Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin, Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad Shazam, Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Chebl, Alex Bou, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, Muhammad A., Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David, Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammed, Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado-Almandoz, Josser, Martin, Jerry C., and Liebeskind, David S.

Published
2019
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15. Contributors

Author

Abecassis, Isaac J., primary, Abruzzo, Todd A., additional, Adel, Joseph G., additional, Aghaebrahim, Amin, additional, Aguilar-Salinas, Pedro, additional, Alimi, Marjan, additional, Aljuboori, Zaid S., additional, Andaluz, Norberto O., additional, Arthur, Adam S., additional, Babadjouni, Robin, additional, Batjer, H. Hunt, additional, Bhambri, Ankur, additional, Binning, Mandy J., additional, Boulos, Alan S., additional, Brasiliense, Leonardo B.C., additional, Brinjikji, Waleed, additional, Carroll, Christopher P., additional, Cheema, Ahmed, additional, Chen, Stephen R., additional, Cherian, Jacob, additional, Cheung, Vincent, additional, Colon, Nathan L., additional, Dalfino, John C., additional, de Oliveira Sillero, Rafael, additional, Dieppa, David S., additional, Effendi, Sabih T., additional, Elwood, Adam, additional, Fargen, Kyle M., additional, Fennell, Vernard S., additional, Fessler, Richard D., additional, Fortuny, Enzo S., additional, Galarza-Paez, Laura, additional, Reid Gooch, M., additional, Gopakumar, Sricharan, additional, Goyal, Nitin, additional, Greenberg, Karen, additional, Griessenauer, Christoph J., additional, Gupta, Vivek, additional, Hanel, Ricardo A., additional, Hamm, Carman Wayne, additional, Hedayat, Hirad S., additional, Hoit, Daniel, additional, Howington, Jay U., additional, James, Robert F., additional, Janjua, Rashid M., additional, Jimenez, Lincoln, additional, Kan, Peter, additional, Khalessi, Alexander, additional, Khan, Usman A., additional, Khattar, Nicolas K., additional, Kim, Louis J., additional, Langer, David J., additional, Lanzino, Giuseppe, additional, Levitt, Michael R., additional, Levy, Elad I., additional, Liebman, Kenneth, additional, Lodi, Yahia M., additional, Mack, William J., additional, Mascitelli, Justin, additional, Mehta, Nikhil, additional, Moore, Kenneth A., additional, Mejia Munne, Juan C., additional, Nickele, Christopher, additional, Obiora, Jeffrey C., additional, Adam Oliver, Thomas, additional, Palma, Atilio, additional, Pandey, Aditya S., additional, Pannell, Jeffrey S., additional, Patel, Maunik, additional, Pollock, Glenn, additional, Rahman, Syed A., additional, Rahme, Ralph, additional, Rennert, Robert C., additional, Ringer, Andrew J., additional, Santos, Roberta, additional, Sauvageau, Eric, additional, Savastano, Luis E., additional, Schirmer, Clemens M., additional, Serrone, Joseph C., additional, Siddiqui, Adnan H., additional, Singh, Jasmeet, additional, Spiotta, Alejandro M., additional, Srinivasan, Visish M., additional, Starke, Robert, additional, Steinberg, Jeffrey A., additional, Stofko, Douglas L., additional, Sudhakar, Tejaswi D., additional, Tackla, Ryan D., additional, Thomas, Justin G., additional, Turner, Raymond D., additional, Vargas, Jan, additional, Veznedaroglu, Erol, additional, Vibhute, Prasanna, additional, Vuong, Shawn M., additional, Walcott, Brian P., additional, Wali, Arvin R., additional, Welch, Babu G., additional, White, Andrew C., additional, White, Jonathan A., additional, White, Timothy G., additional, Wicks, Robert T., additional, Andrew Wilkinson, David, additional, Wilson, John A., additional, Wolfe, Stacey Q., additional, Yamamoto, Junichi, additional, Yim, Benjamin, additional, and Young, Christopher C., additional

Published
2018
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17. Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry

Author

Mueller-Kronast, Nils H., Zaidat, Osama O., Froehler, Michael T., Jahan, Reza, Aziz-Sultan, Mohammad Ali, Klucznik, Richard P., Saver, Jeffrey L., Hellinger, Frank R., Jr, Yavagal, Dileep R., Yao, Tom L., Liebeskind, David S., Jadhav, Ashutosh P., Gupta, Rishi, Hassan, Ameer E., Martin, Coleman O., Bozorgchami, Hormozd, Kaushal, Ritesh, Nogueira, Raul G., Gandhi, Ravi H., Peterson, Eric C., Dashti, Shervin R., Given, Curtis A., II, Mehta, Brijesh P., Deshmukh, Vivek, Starkman, Sidney, Linfante, Italo, McPherson, Scott H., Kvamme, Peter, Grobelny, Thomas J., Hussain, Muhammad S., Thacker, Ike, Vora, Nirav, Chen, Peng Roc, Monteith, Stephen J., Ecker, Robert D., Schirmer, Clemens M., Sauvageau, Eric, Abou-Chebl, Alex, Derdeyn, Colin P., Maidan, Lucian, Badruddin, Aamir, Siddiqui, Adnan H., Dumont, Travis M., Alhajeri, Abdulnasser, Taqi, M. Asif, Asi, Khaled, Carpenter, Jeffrey, Boulos, Alan, Jindal, Gaurav, Puri, Ajit S., Chitale, Rohan, Deshaies, Eric M., Robinson, David H., Kallmes, David F., Baxter, Blaise W., Jumaa, Mouhammad A., Sunenshine, Peter, Majjhoo, Aniel, English, Joey D., Suzuki, Shuichi, Fessler, Richard D., Delgado Almandoz, Josser E., Martin, Jerry C., and Haussen, Diogo C.

Published
2017
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18. Use of intravenous cangrelor in the treatment of ruptured and unruptured cerebral aneurysms: an updated single-center analysis and pooled analysis of current studies.

Author

Entezami, Pouya, Dalfino, John C., Boulos, Alan S., Junichi Yamamoto, Holden, Devin N., Field, Nicholas C., Rock, Andrew K., Najera, Edinson, and Paul, Alexandra R.

Subjects
DRUG efficacy, CEREBRAL embolism & thrombosis, INTRAVENOUS therapy, HEMATOMA, PERITONEUM diseases, INTRACRANIAL hemorrhage, GASTROINTESTINAL hemorrhage, ISCHEMIC stroke, THERAPEUTIC embolization, SURGICAL stents, PLATELET aggregation inhibitors, THROMBOEMBOLISM, DESCRIPTIVE statistics, INTRACRANIAL aneurysms, PATIENT safety, LONGITUDINAL method, EVALUATION, SYMPTOMS
Abstract

Background Intracranial stent placement for the treatment of cerebral aneurysms is increasingly utilized in both ruptured and unruptured scenarios. Intravenous (IV) cangrelor is a relatively new antiplatelet agent that was initially approved for coronary interventions. In addition to our institution, five other centers have published their results using IV cangrelor in neurointerventional procedures. This article combines the aneurysm treatment data from all prior studies to provide insight into the safety and efficacy of cangrelor for intracranial aneurysm treatment. Methods A prospectively maintained database was reviewed to identify all cases of IV cangrelor administration during aneurysm embolization. 20 additional patients were identified who had not been previously published. In addition, a literature search was performed to identify prior publications regarding cangrelor in neurointervention. The data from these were combined with our institutional results in a pooled-analysis. Results Overall, 85 patients who received IV cangrelor during aneurysm embolization were identified, including 46 ruptured and 39 unruptured cases. The asymptomatic and symptomatic intracranial hemorrhage rates were 4% (2/46) for ruptured cases and 2.6% (1/39) for unruptured cases. The rate of retroperitoneal hematoma and gastrointestinal bleeding was 0%. There were no incidents of intraprocedural thromboembolic complication or intraprocedural in-stent thrombosis in either cohort. One subject suffered an ischemic stroke at 24 hours secondary to in-stent thrombosis in a ruptured case. Conclusions IV cangrelor during aneurysm embolization appears to be safe, with a symptomatic intracranial hemorrhage rate of 4% in ruptured cases and 2.6% in unruptured cases. More research is needed to determine the ideal dosing regimen. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Developing a fast-track discharge protocol for patients with cerebral aneurysms treated via neuroendovascular techniques

Author

Entezami, Pouya, primary, Rock, Andrew K., additional, Topp, Gregory P., additional, Heydari, Ehsaun S., additional, Field, Nicholas C., additional, Boulos, Alan S., additional, Dalfino, John C., additional, Yamamoto, Junichi, additional, Pilitsis, Julie G., additional, Cherukupalli, Divya, additional, McCallum, Sarah E., additional, and Paul, Alexandra R., additional

Published
2022
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25. Pipeline Embolization Device for Treatment of Extracranial Internal Carotid Artery Pseudoaneurysms: A Multicenter Evaluation of Safety and Efficacy

Author

Akinduro, Oluwaseun O, primary, Gopal, Neethu, additional, Hasan, Tasneem F, additional, Nourollah-Zadeh, Emad, additional, Vakharia, Kunal, additional, De Leacy, Reade, additional, Burkhardt, Jan-Karl, additional, Yamamoto, Junichi, additional, Mocco, J, additional, Castilla, Leonardo Rangel, additional, Kan, Peter Tze Man, additional, Boulos, Alan, additional, Levy, Elad, additional, and Tawk, Rabih G, additional

Published
2021
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26. Mechanical Thrombectomy of Carotid Terminus Occlusion Using Direct Aspiration Technique—Video Illustration

Author

Al Kasab, Sami, primary, Sattur, Mithun, additional, Porto, Guilherme, additional, Spiotta, Alejandro M, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Jo Binning, Mandy, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad I, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan H, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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27. Treatment of Vertebral Artery Origin Stenosis with Anti-Proliferative Drug-Eluting Stents

Author

Edgell, Randall C., Yavagal, Dileep R., Drazin, Doniel, Olivera, Raul, and Boulos, Alan S.

Subjects
Stenosis -- Care and treatment, Stent (Surgery), Health
Abstract

To authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1552-6569.2008.00330.x Byline: Randall C. Edgell (1), Dileep R. Yavagal (1), Doniel Drazin (1), Raul Olivera (1), Alan S. Boulos (1) Keywords: Vertebral artery origin; stenosis; drug-eluting; stent; stroke Abstract: ABSTRACT BACKGROUND Vertebral artery origin stenosis is a known cause of stroke that is treatable with angioplasty and stenting. Previous studies have demonstrated that this technique is safe but is limited by high rates of in-stent stenosis. Anti-proliferative drug-eluting stents are an alternative for reducing in-stent stenosis at the vertebral artery origin. METHODS This retrospective study included five consecutive patients treated with anti-proliferative drug-eluting stents. The patients' demographics, indications for treatment, procedural technique, and clinical and radiographic follow-up are presented along with a review of the literature. RESULTS No peri-procedural complications occurred. One patient had a transient ischemic attack (TIA) during the follow-up period. No patients had hemodynamically significant (>50%) in-stent stenosis at follow-up. Among the 287 cases reported in the literature, there were two strokes (.7%), four TIAs (1.4%), and no procedurally related deaths. Among patients undergoing angiographic follow-up, 26% were found to have >50% in-stent stenosis. CONCLUSIONS Anti-proliferative drug-eluting stents hold promise for reducing in-stent stenosis at the vertebral artery origin. Author Affiliation: (1)From the Department of Surgery, Division of Neurosurgery, St. Louis University, St. Louis, MO (RCE, RO); Department of Neurology and Psychiatry, St. Louis University, St. Louis, MO (RCE); Department of Neurology, University of Miami, Miami, FL (DRY); Department of Surgery, Division of Neurosurgery, Albany Medical Center, Albany, NY (DD, ASB). Article History: Acceptance: Received September 2, 2008, and in revised from August 7, 2008. Accepted for publication September 24, 2008. Article note: Correspondence: Address correspondence to Randall C. Edgell, MD, Division of Neurosurgery, 3635 Vista Avenue at Grand, St. Louis, MO 63110. E-mail: randall.edgell@gmail.com

Published
2010

28. sj-pdf-1-ine-10.1177_15910199211014417 - Supplemental material for Use of intravenous cangrelor and stenting in acute ischemic stroke interventions: a new single center analysis and pooled-analysis of current studies

Author

Paul, Alexandra R, Pouya Entezami, Holden, Devin, Field, Nicholas, Dalfino, John, and Boulos, Alan

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-pdf-1-ine-10.1177_15910199211014417 for Use of intravenous cangrelor and stenting in acute ischemic stroke interventions: a new single center analysis and pooled-analysis of current studies by Alexandra R Paul, Pouya Entezami, Devin Holden, Nicholas Field, John Dalfino and Alan Boulos in Interventional Neuroradiology

Published
2021
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30. Neuroendovascular Management of Acute Ischemic Basilar Strokes

Author

Porto, Guilherme B F, primary, Sattur, Mithun G, additional, Al Kasab, Sami, additional, Spiotta, Alejandro M, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Jo Binning, Mandy, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad I, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan H, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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31. Ulnar Artery Access

Author

Dossani, Rimal H, primary, Waqas, Muhammad, additional, Cappuzzo, Justin M, additional, Sonig, Ashish, additional, Almayman, Faisal, additional, Siddiqui, Adnan H, additional, Levy, Elad I, additional, Davies, Jason M, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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32. Management of Mobile Thrombus With Distal Protection Devices During Carotid Artery Angioplasty

Author

Cohen-Cohen, Salomon, primary, Lanzino, Giuseppe, additional, Brinjikji, Waleed, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Levitt, Michael, additional, Levy, Elad I, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan H, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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33. Safety and efficacy results of the Flow Redirection Endoluminal Device (FRED) stent system in the treatment of intracranial aneurysms: US pivotal trial

Author

McDougall, Cameron G, primary, Diaz, Orlando, additional, Boulos, Alan, additional, Siddiqui, Adnan H, additional, Caplan, Justin, additional, Fifi, Johanna T, additional, Turk, Aquilla S, additional, Kayan, Yasha, additional, Jabbour, Pascal, additional, Kim, Louis J, additional, Hetts, Steven W, additional, Cooke, Daniel L, additional, and Dowd, Christopher F, additional

Published
2021
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34. Middle Cerebral Artery Thrombectomy

Author

Rangwala, Shivani D, primary, Selvan, Pradeep, additional, Tenser, Matthew, additional, Mack, William, additional, Arthur, Adam, additional, Mark, Bain, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad I, additional, Lopes, Demetrius, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan H, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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35. Endovascular Treatment of Basilar Bifurcation Aneurysms With PulseRider-Assisted Coiling

Author

Sattur, Mithun G, primary, Al Kasab, Sami, additional, Porto, Guilherme B, additional, Spiotta, Alejandro M, additional, Arthur, Adam, additional, Mark, Bain, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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36. Intracranial Access

Author

Domingo, Ricardo A, primary, Ravindran, Krishnan, additional, Kulakova, Katya, additional, Tawk, Rabih G, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad I, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan H, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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37. Intracranial Stenting

Author

Dossani, Rimal H, primary, Waqas, Muhammad, additional, Cappuzzo, Justin M, additional, Sonig, Ashish, additional, Siddiqui, Adnan H, additional, Levy, Elad I, additional, Davies, Jason M, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Jo Binning, Mandy, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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38. Carotid Stenting

Author

Domingo, Ricardo A, primary, Ravindran, Krishnan, additional, Tawk, Rabih G, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Jo Binning, Mandy, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad I, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan H, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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39. Multicenter analysis of the incidence of in-stent stenosis following the deployment of flow-redirection endoluminal device in the treatment of intracranial aneurysms

Author

Gajjar, Avi A., Sioutas, Georgios S., Custozzo, Amanda, Salem, Mohamed M., Field, Nicholas C., Shekhtman, Oleg, Davis, Pierce, Prabhala, Tarun, Jankowitz, Brian T., Dalfino, John C., Boulos, Alan S., Burkhardt, Jan-Karl, Paul, Alexandra R., and Srinivasan, Visish M.

Abstract

Introduction The Flow Re-direction Endoluminal Device (FRED) is a novel flow diverter with a unique double stent design, with an inner stent composed of 48 nitinol wires, and an outer stent with 16 nitinol wires. It is designed for endovascular cerebral aneurysm treatment, although, limited data exist regarding in-stent stenosis (ISS) rates associated with FRED devices.Methods A registry encompassing two North American comprehensive stroke centers was the base of this study. We longitudinally assessed patients implanted with FRED devices, emphasizing baseline demographics, aneurysmal characteristics, procedural data, aneurysmal occlusion, and the incidence of ISS.Results In our cohort of 87 patients receiving 88 FRED devices, ISS occurred in 10.4% (9) of cases. Mild ISS (<50%) was noted in 8.0% (7) of patients, moderate ISS (50–75%) in 1.1% (1), and severe ISS (>75%) in 1.1% (1). Analysis indicated ISS in 17.0% (8) of patients with the FRED device and 5.7% (2) with the FRED-X device; all ISS cases in the FRED-X group were mild. Differences in ISS rates between device types were not significant (p= 0.122). Delayed thrombotic events were documented in 6.9% (6) of patients. Aneurysm occlusion rates, measured via the Raymond–Roy Scale (RRS), showed adequate occlusion (RRS 1 or 2) in 68.8% at 3 months, 74.6% at 6 months, and 89.3% at 12 months.Conclusions The study elucidates the efficacy and safety profile of FRED devices, presenting favorable aneurysm occlusion rates and low retreatment needs while underscoring the manageability of ISS.

Published
2025
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41. Crossing the Carotid Siphon

Author

Hadley, Caroline, primary, Burkhardt, Jan-Karl, additional, Johnson, Jeremiah N, additional, Kan, Peter, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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43. The Role of Angioplasty Alone in Intracranial Atherosclerosis

Author

Cohen-Cohen, Salomon, primary, Lanzino, Giuseppe, additional, Brinjikji, Waleed, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Jo Binning, Mandy, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Levitt, Michael, additional, Levy, Elad, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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44. Management of Thromboembolic Complications During Aneurysm Coiling

Author

Domingo, Ricardo A, primary, Martinez Santos, Jaime L, additional, Ravindran, Krishnan, additional, Tawk, Rabih G, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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46. Contributors

Author

Abe, Takato, primary, Adams, Harold P., additional, Adeoye, Opeolu, additional, Agarwal, Sachin, additional, Aguilar, Maria I., additional, Al-Khoury, Lama, additional, Arboix, Adrià, additional, Auer, Roland N., additional, Awad, Issam A., additional, Baird, Alison E., additional, Baltan, Selva, additional, Barnett, Henry J.M., additional, Batjer, H. Hunt, additional, Benavente, Oscar R., additional, Bendok, Bernard R., additional, Bershad, Eric M., additional, Binder, Jeffrey R., additional, Boulos, Alan S., additional, Bousser, Marie-Germaine, additional, Bova, Frank J., additional, Brainin, Michael, additional, Brisman, Jonathan L., additional, Brown, Wendy, additional, Brust, John C.M., additional, Canhão, Patrícia, additional, Caplan, Louis R., additional, Castellanos, Mar, additional, Chabriat, Hugues, additional, Chamorro, Angel, additional, Choi, Jae H., additional, Chopp, Michael, additional, Connolly, E. Sander, additional, Coull, Bruce M., additional, Cucchiara, Brett L., additional, Dalkara, Turgay, additional, Dani, Krishna A., additional, Dannenbaum, Mark J., additional, Dashti, Shervin R., additional, Davis, Patricia H., additional, Dawson, Ted M., additional, Dawson, Valina L., additional, Day, Arthur L., additional, De Leo, Michael J., additional, del Zoppo, Gregory J., additional, Diedler, Jennifer, additional, Diener, Hans-Christoph, additional, Di Tullio, Marco R., additional, Dobkin, Bruce H., additional, Drake, Kendra, additional, Du, Rose, additional, Ducros, Anne, additional, Dzialowski, Imanuel, additional, Eddleman, Christopher S., additional, Elhammady, Mohamed Samy, additional, Elkind, Mitchell S.V., additional, Elliott, J. Paul, additional, Ferro, José M., additional, Findlay, J. Max, additional, Friedman, William A., additional, Furie, Karen L., additional, Furlan, Anthony J., additional, Geibprasert, Sasikhan, additional, Gobin, Y. Pierre, additional, Goldberg, Mark P., additional, Goldstein, Larry B., additional, Gonzales, Nicole R., additional, Gounis, Matthew J., additional, Greenberg, Steven M., additional, Greer, David M., additional, Grotta, James C., additional, Hacke, Werner, additional, Hallenbeck, John, additional, Hamann, Gerhard F., additional, Hartmann, Andreas, additional, Hennerici, Michael, additional, Heros, Roberto C., additional, Higashida, Randall, additional, Homma, Shunichi, additional, Hongo, Kazuhiro, additional, Hopkins, L. Nelson, additional, Horiuchi, Tetsuyoshi, additional, Howard, George, additional, Howard, Virginia J., additional, Huddle, Daniel, additional, Iadecola, Costantino, additional, Joutel, Anne, additional, Jüttler, Eric, additional, Kakarla, Udaya K., additional, Kalafut, Mary A., additional, Kannel, William B., additional, Kase, Carlos S., additional, Kasner, Scott E., additional, Kaste, Markku, additional, Khaw, Alexander, additional, Kidwell, Chelsea S., additional, Kim, Helen, additional, Kim, Louis J., additional, Kim, Stanley H., additional, Klijn, Catharina J.M. (Karin), additional, Kobayashi, Shigeaki, additional, Komotar, Ricardo J., additional, Krings, Timo, additional, Kunz, Alexander, additional, Kurth, Tobias, additional, Lamy, Catherine, additional, Lazar, Ronald M., additional, Levy, Elad I., additional, Liebeskind, David S., additional, Lyden, Patrick D., additional, Markham, Joanne, additional, Marshall, Randolph S., additional, Martí-Vilalta, J.L., additional, Mas, Jean-Louis, additional, Mast, Henning, additional, Masuda, Junichi, additional, Mathers, Colin D., additional, Mayberg, Marc R., additional, Meairs, Stephen, additional, Mendelow, Alexander David, additional, Meschia, James F., additional, Miller, Alyson A., additional, Miyawaki, Takahiro, additional, Mocco, J, additional, Mohr, J.P., additional, Morcos, Jacques J., additional, Morgenstern, Lewis B., additional, Moskowitz, Michael A., additional, Nahed, Brian V., additional, Newell, David W., additional, Ofengeim, Dimitry, additional, Ogata, Jun, additional, Ogilvy, Christopher S., additional, Palesch, Yuko Y., additional, Pancioli, Arthur, additional, Park, Min S., additional, Pawlikowska, Ludmila, additional, Pile-Spellman, John, additional, Powers, William J., additional, Puetz, Volker, additional, Ransom, Bruce R., additional, Roine, Risto O., additional, Ruigrok, Ynte M., additional, Rundek, Tatjana, additional, Sacco, Ralph L., additional, Sattenberg, Ronald J., additional, Saver, Jeffrey L., additional, Savitz, Sean I., additional, Seshadri, Sudha, additional, Sharma, Jitendra, additional, Silverboard, Gerald, additional, Singhal, Aneesh B., additional, Sobey, Christopher G., additional, Spetzler, Robert F., additional, Stapf, Christian, additional, Starke, Robert M., additional, Stiefel, Michael F., additional, Strong, Kathleen, additional, Suarez, José I., additional, Sykora, Marek, additional, Tafreshi, Gilda, additional, Brugge, Karel ter, additional, Tilley, Barbara C., additional, Toni, Danilo, additional, Tournier-Lasserve, Elisabeth, additional, Vilela, Marcelo D., additional, von Kummer, Rüdiger, additional, Wakhloo, Ajay K., additional, Warach, Steven, additional, Weksler, Babette B., additional, Willey, Joshua Z., additional, Wintermark, Max, additional, Wolf, Philip A., additional, Woo, Daniel, additional, Yamaguchi, Takenori, additional, Yasaka, Masahiro, additional, Young, William L., additional, Zahuranec, Darin B., additional, Zazulia, Allyson R., additional, Zhang, Zheng Gang, additional, Zukin, R. Suzanne, additional, and Zweifler, Richard M., additional

Published
2011
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49. Aspiration Thrombectomy

Author

Turner, Raymond, primary, Turk, Aquilla, additional, Chaudry, Imran, additional, Vargas, Jan, additional, Arthur, Adam, additional, Bain, Mark, additional, Bendock, Bernard, additional, Binning, Mandy Jo, additional, Boulos, Alan S, additional, Crowley, Webster, additional, Fessler, Richard, additional, Grande, Andrew, additional, Guterman, Lee, additional, Hanel, Ricardo, additional, Hoit, Daniel, additional, Hopkins, L Nelson, additional, Howington, Jay, additional, James, Robert, additional, Jankowitz, Brian, additional, Kan, Peter, additional, Khalessi, Alex A, additional, Kim, Louis, additional, Langer, David, additional, Lanzino, Giuseppe, additional, Levitt, Michael, additional, Levy, Elad, additional, Lopes, Demetrius, additional, Mack, William, additional, Mericle, Robert, additional, Mocco, J, additional, Ogilvy, Chris, additional, Pandey, Aditya, additional, Replogle, Robert, additional, Riina, Howard, additional, Ringer, Andrew, additional, Rodriguez, Rafael, additional, Saugaveau, Eric, additional, Schirmer, Clemens, additional, Siddiqui, Adnan, additional, Spiotta, Alex, additional, Sultan, Ali, additional, Tawk, Rabih, additional, Thomas, Ajith, additional, Turner, Raymond, additional, Veznedaroglu, Erol, additional, Welch, Babu, additional, and White, Jonathan, additional

Published
2021
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