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34 results on '"Boulygina, Eugenia S."'

1. Genetic contribution of domestic European common carp (Cyprinus carpio carpio) and Amur carp (Cyprinus carpio haematopterus) to the wild Vietnamese carp population as revealed by ddRAD sequencing

Author

Nedoluzhko, Artem V., Gladysheva-Azgari, Maria V., Shalgimbayeva, Gulmira M., Volkov, Alexander A., Slobodova, Natalia V., Tsygankova, Svetlana V., Boulygina, Eugenia S., Nguyen, Van Q., Pham, The T., Nguyen, Duc T., Sharko, Fedor S., and Rastorguev, Sergey M.

Published
2021
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2. Koban culture genome-wide and archeological data open the bridge between Bronze and Iron Ages in the North Caucasus

Author

Sharko, Fedor S., primary, Boulygina, Eugenia S., additional, Tsygankova, Svetlana V., additional, Slobodova, Natalia V., additional, Rastorguev, Sergey M., additional, Krasivskaya, Anna A., additional, Belinsky, Andrej B., additional, Härke, Heinrich, additional, Kadieva, Anna A., additional, Demidenko, Sergej V., additional, Malashev, Vladimir Yu., additional, Shvedchikova, Tatiana Yu., additional, Dobrovolskaya, Maria V., additional, Reshetova, Irina K., additional, Korobov, Dmitry S., additional, and Nedoluzhko, Artem V., additional

Published
2024
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8. A new strain group of common carp: The genetic differences and admixture events between Cyprinus carpio breeds

Author

Nedoluzhko, Artem V., primary, Slobodova, Natalia V., additional, Sharko, Fedor, additional, Shalgimbayeva, Gulmira M., additional, Tsygankova, Svetlana V., additional, Boulygina, Eugenia S., additional, Jeney, Zsigmond, additional, Nguyen, Van Q., additional, Pham, Thế T., additional, Nguyen, Đức T., additional, Volkov, Alexander A., additional, Fernandes, Jorge M.O., additional, and Rastorguev, Sergey M., additional

Published
2020
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9. A partial genome assembly of the miniature parasitoid wasp, Megaphragma amalphitanum

Author

Sharko, Fedor S., primary, Nedoluzhko, Artem V., additional, Lê, Brandon M., additional, Tsygankova, Svetlana V., additional, Boulygina, Eugenia S., additional, Rastorguev, Sergey M., additional, Sokolov, Alexey S., additional, Rodriguez, Fernando, additional, Mazur, Alexander M., additional, Polilov, Alexey A., additional, Benton, Richard, additional, Evgen'ev, Michael B., additional, Arkhipova, Irina R., additional, Prokhortchouk, Egor B., additional, and Skryabin, Konstantin G., additional

Published
2019
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10. The complete mitochondrial genome of the extinct Pleistocene horse (Equus cf. lenensis) from Kotelny Island (New Siberian Islands, Russia) and its phylogenetic assessment

Author

Nedoluzhko, Artem V., primary, Sharko, Fedor S., additional, Boulygina, Eugenia S., additional, Tsygankova, Svetlana V., additional, Slobodova, Natalia V., additional, Gruzdeva, Natalia M., additional, Rastorguev, Sergey M., additional, Spasskaya, Natalia N., additional, and Maschenko, Evgeny N., additional

Published
2019
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12. Phylogenetic position of the presumably extinct slender-billed curlew, Numenius tenuirostris

Author

Sharko, Fedor S., Boulygina, Eugenia S., Rastorguev, Sergey M., Tsygankova, Svetlana V., Tomkovich, Pavel S., and Nedoluzhko, Artem V.

Abstract

The high-capacity DNA analysis of museum samples opens new opportunities, associated with the investigation of extinct species evolution. Here, the complete mitochondrial genome of the presumably extinct bird species, the slender-billed curlew Numenius tenuirostris (Charadriiformes: Scolopacidae) is presented. Our results showed that mitochondrial DNA (mtDNA) is 16,705 base pairs (bp) in length and contain 13 protein-coding genes, two rRNA genes, and 22 tRNA genes. The overall base composition of the genome is 30.8% – A, 29.8% – C, 25.4% – T, 14.0% – G, and without a significant GC bias of 43.7%. Phylogenetic analyses based on the cytochrome B (cytB) gene and the whole mtDNA sequences revealed that N. tenuirostris had a close genetic relationship to Eurasian curlew (N. arquata), Far Eastern curlew (N. madagascariensis), and long-billed curlew – N. americanus. Besides, it reveals that Numenius genus is genetically distant from other Scolopacidae taxons. Together, these results provide a clear genetic perspective into the speciation process among the curlew genus members and points to a clear taxonomic position of N. tenuirostris.

Published
2019
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14. A draft genome sequence of the miniature parasitoid wasp, Megaphragma amalphitanum

Author

Nedoluzhko, Artem V., primary, Sharko, Fedor S., additional, Lê, Brandon M., additional, Tsygankova, Svetlana V., additional, Boulygina, Eugenia S., additional, Rastorguev, Sergey M., additional, Sokolov, Alexey S., additional, Rodriguez, Fernando, additional, Mazur, Alexander M., additional, Polilov, Alexey A., additional, Benton, Richard, additional, Evgen’ev, Michael B., additional, Arkhipova, Irina R., additional, Prokhortchouk, Egor B., additional, and Skryabin, Konstantin G., additional

Published
2019
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15. Common colorectal cancer risk alleles contribute to the multiple colorectal adenoma phenotype, but do not influence colonic polyposis in FAP

Author

Cheng, Timothy H. T, Gorman, Maggie, Martin, Lynn, Barclay, Ella, Casey, Graham, Newcomb, Polly A., Conti, David V., Schumacher, Fred, Gallinger, Steve, Lindor, Noralane M., Hopper, John, Jenkins, Mark, Hunter, David J., Kraft, Peter, Jacobs, Kevin B., Cox, David G., Yeager, Meredith, Hankinson, Susan E., Wacholder, Sholom, Wang, Zhaoming, Welch, Robert, Hutchinson, Amy, Wang, Junwen, Yu, Kai, Chatterjee, Nilanjan, Orr, Nick, Willett, Walter C., Colditz, Graham A., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., Mccarty, Catherine A., Feigelson, Heather Spencer, Calle, Eugenia E., Thun, Michael J., Hayes, Richard B., Tucker, Margaret, Gerhard, Daniela S., Fraumeni, Joseph F., Hoover, Robert N., Thomas, Gilles, Chanock, Stephen J., Ciampa, Julia, Gonzalez Bosquet, Jesus, Berndt, Sonja, Amundadottir, Laufey, Diver, W. Ryan, Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie, Schumacher, Fredrick R., Cancel Tassin, Geraldine, Cussenot, Olivier, Valeri, Antoine, Andriole, Gerald L., Crawford, E. David, Haiman, Christopher A., Henderson, Brian, Kolonel, Laurence, Marchand, Loic Le, Siddiq, Afshan, Riboli, Elio, Key, Timothy J., Kaaks, Rudolf, Isaacs, William, Isaacs, Sarah, Wiley, Kathleen E., Gronberg, Henrik, Wiklund, Fredrik, Stattin, Pär, Xu, Jianfeng, Zheng, S. Lilly, Sun, Jielin, Vatten, Lars J., Hveem, Kristian, Kumle, Merethe, Purdue, Mark P., Johansson, Mattias, Zelenika, Diana, Toro, Jorge R., Scelo, Ghislaine, Moore, Lee E., Prokhortchouk, Egor, Wu, Xifeng, Kiemeney, Lambertus A., Gaborieau, Valerie, Chow, Wong Ho, Zaridze, David, Matveev, Vsevolod, Lubinski, Jan, Trubicka, Joanna, Szeszenia Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Péter, Fabianova, Eleonora, Bucur, Alexandru, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Colt, Joanne S., Davis, Faith G., Schwartz, Kendra L., Banks, Rosamonde E., Selby, Peter J., Harnden, Patricia, Hsing, Ann W., Grubb, Robert L., Boeing, Heiner, Vineis, Paolo, Clavel Chapelon, Franc¸oise, Palli, Domenico, Tumino, Rosario, Krogh, Vittorio, Duell, Eric J., Quirós, José Ramón, Sanchez, Maria José, Navarro, Carmen, Ardanaz, Eva, Dorronsoro, Miren, Khaw, Kay Tee, Allen, Naomi E., Bueno de Mesquita, H. Bas, Peeters, Petra H. M., Trichopoulos, Dimitrios, Linseisen, Jakob, Ljungberg, Börje, Overvad, Kim, Tjønneland, Anne, Romieu, Isabelle, Mukeria, Anush, Shangina, Oxana, Stevens, Victoria L., Gapstur, Susan M., Pharoah, Paul D., Easton, Douglas F., Weinstein, Stephanie J., Njølstad, Inger, Tell, Grethe S., Stoltenberg, Camilla, Kumar, Rajiv, Koppova, Kvetoslava, Benhamou, Simone, Oosterwijk, Egbert, Vermeulen, Sita H., Aben, Katja K. H., Van Der Marel, Saskia L., Ye, Yuanqing, Wood, Christopher G., Pu, Xia, Mazur, Alexander M., Boulygina, Eugenia S., Chekanov, Nikolai N., Foglio, Mario, Lechner, Doris, Gut, Ivo, Heath, Simon, Blanche, Hélène, Skryabin, Konstantin G., Mckay, James D., Rothman, Nathaniel, Lathrop, Mark, Brennan, Paul, Saunders, Brian, Thomas, Huw, Clark, Sue, Tomlinson, Ian, PANICO, SALVATORE, Cheng, Timothy H. T, Gorman, Maggie, Martin, Lynn, Barclay, Ella, Casey, Graham, Newcomb, Polly A., Conti, David V., Schumacher, Fred, Gallinger, Steve, Lindor, Noralane M., Hopper, John, Jenkins, Mark, Hunter, David J., Kraft, Peter, Jacobs, Kevin B., Cox, David G., Yeager, Meredith, Hankinson, Susan E., Wacholder, Sholom, Wang, Zhaoming, Welch, Robert, Hutchinson, Amy, Wang, Junwen, Yu, Kai, Chatterjee, Nilanjan, Orr, Nick, Willett, Walter C., Colditz, Graham A., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., Mccarty, Catherine A., Feigelson, Heather Spencer, Calle, Eugenia E., Thun, Michael J., Hayes, Richard B., Tucker, Margaret, Gerhard, Daniela S., Fraumeni, Joseph F., Hoover, Robert N., Thomas, Gille, Chanock, Stephen J., Ciampa, Julia, Gonzalez Bosquet, Jesu, Berndt, Sonja, Amundadottir, Laufey, Diver, W. Ryan, Albanes, Demetriu, Virtamo, Jarmo, Weinstein, Stephanie, Schumacher, Fredrick R., Cancel Tassin, Geraldine, Cussenot, Olivier, Valeri, Antoine, Andriole, Gerald L., Crawford, E. David, Haiman, Christopher A., Henderson, Brian, Kolonel, Laurence, Marchand, Loic Le, Siddiq, Afshan, Riboli, Elio, Key, Timothy J., Kaaks, Rudolf, Isaacs, William, Isaacs, Sarah, Wiley, Kathleen E., Gronberg, Henrik, Wiklund, Fredrik, Stattin, Pär, Xu, Jianfeng, Zheng, S. Lilly, Sun, Jielin, Vatten, Lars J., Hveem, Kristian, Kumle, Merethe, Purdue, Mark P., Johansson, Mattia, Zelenika, Diana, Toro, Jorge R., Scelo, Ghislaine, Moore, Lee E., Prokhortchouk, Egor, Wu, Xifeng, Kiemeney, Lambertus A., Gaborieau, Valerie, Chow, Wong Ho, Zaridze, David, Matveev, Vsevolod, Lubinski, Jan, Trubicka, Joanna, Szeszenia Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Péter, Fabianova, Eleonora, Bucur, Alexandru, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Colt, Joanne S., Davis, Faith G., Schwartz, Kendra L., Banks, Rosamonde E., Selby, Peter J., Harnden, Patricia, Hsing, Ann W., Grubb, Robert L., Boeing, Heiner, Vineis, Paolo, Clavel Chapelon, Franc¸oise, Palli, Domenico, Tumino, Rosario, Krogh, Vittorio, Panico, Salvatore, Duell, Eric J., Quirós, José Ramón, Sanchez, Maria José, Navarro, Carmen, Ardanaz, Eva, Dorronsoro, Miren, Khaw, Kay Tee, Allen, Naomi E., Bueno de Mesquita, H. Ba, Peeters, Petra H. M., Trichopoulos, Dimitrio, Linseisen, Jakob, Ljungberg, Börje, Overvad, Kim, Tjønneland, Anne, Romieu, Isabelle, Mukeria, Anush, Shangina, Oxana, Stevens, Victoria L., Gapstur, Susan M., Pharoah, Paul D., Easton, Douglas F., Weinstein, Stephanie J., Njølstad, Inger, Tell, Grethe S., Stoltenberg, Camilla, Kumar, Rajiv, Koppova, Kvetoslava, Benhamou, Simone, Oosterwijk, Egbert, Vermeulen, Sita H., Aben, Katja K. H., Van Der Marel, Saskia L., Ye, Yuanqing, Wood, Christopher G., Pu, Xia, Mazur, Alexander M., Boulygina, Eugenia S., Chekanov, Nikolai N., Foglio, Mario, Lechner, Dori, Gut, Ivo, Heath, Simon, Blanche, Hélène, Skryabin, Konstantin G., Mckay, James D., Rothman, Nathaniel, Lathrop, Mark, Brennan, Paul, Saunders, Brian, Thomas, Huw, Clark, Sue, and Tomlinson, Ian

Subjects
Adenoma, Allele, Male, Genes, Modifier, Adenomatous Polyposis Coli Protein, Colorectal Neoplasm, Middle Aged, Polymorphism, Single Nucleotide, Phenotype, Adenomatous Polyposis Coli, Genetics, Female, Genetic Predisposition to Disease, DNA Glycosylase, Germ-Line Mutation, Genetics (clinical), Aged, Human
Abstract

The presence of multiple (5-100) colorectal adenomas suggests an inherited predisposition, but the genetic aetiology of this phenotype is undetermined if patients test negative for Mendelian polyposis syndromes such as familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP). We investigated whether 18 common colorectal cancer (CRC) predisposition single-nucleotide polymorphisms (SNPs) could help to explain some cases with multiple adenomas who phenocopied FAP or MAP, but had no pathogenic APC or MUTYH variant. No multiple adenoma case had an outlying number of CRC SNP risk alleles, but multiple adenoma patients did have a significantly higher number of risk alleles than population controls (P=5.7 × 10(-7)). The association was stronger in those with ≥10 adenomas. The CRC SNPs accounted for 4.3% of the variation in multiple adenoma risk, with three SNPs (rs6983267, rs10795668, rs3802842) explaining 3.0% of the variation. In FAP patients, the CRC risk score did not differ significantly from the controls, as we expected given the overwhelming effect of pathogenic germline APC variants on the phenotype of these cases. More unexpectedly, we found no evidence that the CRC SNPs act as modifier genes for the number of colorectal adenomas in FAP patients. In conclusion, common colorectal tumour risk alleles contribute to the development of multiple adenomas in patients without pathogenic germline APC or MUTYH variants. This phenotype may have 'polygenic' or monogenic origins. The risk of CRC in relatives of multiple adenoma cases is probably much lower for cases with polygenic disease, and this should be taken into account when counselling such patients.

Published
2015

19. Radioisotopic, culture-based, and oligonucleotide microchip analyses of thermophilic microbial communities in a continental high-temperature petroleum reservoir

Author

Bonch-Osmolovskaya, Elizaveta A., Miroshnichenko, Margarita, Lebedinsky, Alexander V., Chernyh, Nikolai A., Nazima, Tamara N., Ivoilov, Valery S., Belyaev, Sergey S., Boulygina, Eugenia S., Lysov, Yury P., Perov, Alexander N., Mirzabekov, Andrei D., Hippe, Hans, Stackebrandt, erko, L'Haridon, Stephane, and Jeanthon, Christian

Subjects
Statistics, Biotic communities -- Analysis, Bacteria, Thermophilic -- Environmental aspects, Biological sciences
Abstract

Research reveals that diverse physiological groups of aerobic and anaerobic thermophiles and hyperthermophiles, with fermentative organotrops predominating, occur in formation waters of the high-temperaure oil reservoir.

Published
2003

20. Draft Genome Sequence of “ Halomonas chromatireducens ” Strain AGD 8-3, a Haloalkaliphilic Chromate- and Selenite-Reducing Gammaproteobacterium

Author

Sharko, Fedor S., primary, Shapovalova, Anna A., additional, Tsygankova, Svetlana V., additional, Komova, Anastasia V., additional, Boulygina, Eugenia S., additional, Teslyuk, Anton B., additional, Gotovtsev, Pavel M., additional, Namsaraev, Zorigto B., additional, Khijniak, Tatiana V., additional, Nedoluzhko, Artem V., additional, and Vasilov, Raif G., additional

Published
2016
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21. The complete mitochondrial genome of the extinct Pleistocene horse (Equus cf. lenensis) from Kotelny Island (New Siberian Islands, Russia) and its phylogenetic assessment.

Author

Nedoluzhko, Artem V., Sharko, Fedor S., Boulygina, Eugenia S., Tsygankova, Svetlana V., Slobodova, Natalia V., Gruzdeva, Natalia M., Rastorguev, Sergey M., Spasskaya, Natalia N., and Maschenko, Evgeny N.

Subjects
EQUUS, PERCIFORMES, BASE pairs, HORSES, GENOMES, ISLANDS, MITOCHONDRIAL DNA
Abstract

The complete mitochondrial genome from the Pleistocene stallion horse (Equus cf. lenensis) which complete skull was found in 1901 on Kotelny Island (New Siberian Archipelago, Sakha Republic, Russia) is published in this paper. The mitochondrial DNA (mtDNA) is 16,584 base pairs (bp) in length and contained 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes. The overall base composition of the genome in descending order was 32.3% – A, 28.5% – C, 13.4% – G, 25.8% - T without a significant AT bias of 58.2%. [ABSTRACT FROM AUTHOR]

Published
2020
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23. Study of Alzheimer family case reveals hemochromotosis-associated HFE mutation

Author

Artemov, Artem V, primary, Boulygina, Eugenia S, additional, Tsygankova, Svetlana V, additional, Nedoluzhko, Artem V, additional, Chekanov, Nikolay N, additional, Gruzdeva, Natalia M, additional, Selezneva, Natalia D, additional, Roshchina, Irina F, additional, Gavrilova, Svetlana I, additional, Velichkovsky, Boris B, additional, Skryabin, Konstantin G, additional, and Prokhortchouk, Egor B, additional

Published
2014
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24. Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

Author

Purdue, Mark P, primary, Johansson, Mattias, additional, Zelenika, Diana, additional, Toro, Jorge R, additional, Scelo, Ghislaine, additional, Moore, Lee E, additional, Prokhortchouk, Egor, additional, Wu, Xifeng, additional, Kiemeney, Lambertus A, additional, Gaborieau, Valerie, additional, Jacobs, Kevin B, additional, Chow, Wong-Ho, additional, Zaridze, David, additional, Matveev, Vsevolod, additional, Lubinski, Jan, additional, Trubicka, Joanna, additional, Szeszenia-Dabrowska, Neonila, additional, Lissowska, Jolanta, additional, Rudnai, Péter, additional, Fabianova, Eleonora, additional, Bucur, Alexandru, additional, Bencko, Vladimir, additional, Foretova, Lenka, additional, Janout, Vladimir, additional, Boffetta, Paolo, additional, Colt, Joanne S, additional, Davis, Faith G, additional, Schwartz, Kendra L, additional, Banks, Rosamonde E, additional, Selby, Peter J, additional, Harnden, Patricia, additional, Berg, Christine D, additional, Hsing, Ann W, additional, Grubb, Robert L, additional, Boeing, Heiner, additional, Vineis, Paolo, additional, Clavel-Chapelon, Françoise, additional, Palli, Domenico, additional, Tumino, Rosario, additional, Krogh, Vittorio, additional, Panico, Salvatore, additional, Duell, Eric J, additional, Quirós, José Ramón, additional, Sanchez, Maria-José, additional, Navarro, Carmen, additional, Ardanaz, Eva, additional, Dorronsoro, Miren, additional, Khaw, Kay-Tee, additional, Allen, Naomi E, additional, Bueno-de-Mesquita, H Bas, additional, Peeters, Petra H M, additional, Trichopoulos, Dimitrios, additional, Linseisen, Jakob, additional, Ljungberg, Börje, additional, Overvad, Kim, additional, Tjønneland, Anne, additional, Romieu, Isabelle, additional, Riboli, Elio, additional, Mukeria, Anush, additional, Shangina, Oxana, additional, Stevens, Victoria L, additional, Thun, Michael J, additional, Diver, W Ryan, additional, Gapstur, Susan M, additional, Pharoah, Paul D, additional, Easton, Douglas F, additional, Albanes, Demetrius, additional, Weinstein, Stephanie J, additional, Virtamo, Jarmo, additional, Vatten, Lars, additional, Hveem, Kristian, additional, Njølstad, Inger, additional, Tell, Grethe S, additional, Stoltenberg, Camilla, additional, Kumar, Rajiv, additional, Koppova, Kvetoslava, additional, Cussenot, Olivier, additional, Benhamou, Simone, additional, Oosterwijk, Egbert, additional, Vermeulen, Sita H, additional, Aben, Katja K H, additional, van der Marel, Saskia L, additional, Ye, Yuanqing, additional, Wood, Christopher G, additional, Pu, Xia, additional, Mazur, Alexander M, additional, Boulygina, Eugenia S, additional, Chekanov, Nikolai N, additional, Foglio, Mario, additional, Lechner, Doris, additional, Gut, Ivo, additional, Heath, Simon, additional, Blanche, Hélène, additional, Hutchinson, Amy, additional, Thomas, Gilles, additional, Wang, Zhaoming, additional, Yeager, Meredith, additional, Fraumeni, Joseph F, additional, Skryabin, Konstantin G, additional, McKay, James D, additional, Rothman, Nathaniel, additional, Chanock, Stephen J, additional, Lathrop, Mark, additional, and Brennan, Paul, additional

Published
2010
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29. Two complete mitochondrial genomes of extinct form of the Sevan trout <italic>Salmo ischchan danilewskii</italic>.

Author

Nedoluzhko, Artem V., Rastorguev, Sergey M., Simonov, Evgeniy, Boulygina, Eugenia S., Sharko, Fedor S., Tsygankova, Svetlana V., Gabrielyan, Bardukh K., Roubenyan, Haikaz R., and Levin, Boris A.

Subjects
SALMO, FISHES, MITOCHONDRIAL DNA, FISH genomes, EXTINCT fishes, BASE pairs
Abstract

The mitochondrial genomes from two individuals of the extinct subspecies of the Sevan trout Salmo ischchan danilewskii are published in this paper. The mitochondrial DNA (mtDNA) is 16,665 base pairs (bp) in length and contained 13 protein-coding genes, 2 rRNA genes, and 22 tRNA genes. The overall base composition of the genome in descending order was 27.9% of A, 29.4% of C, 16.7% of G, and 26.0% of T without a significant AT bias of 53.9%. [ABSTRACT FROM AUTHOR]

Published
2018
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30. First description of a mummified Middle Holocene brown bear from the New Siberian Islands, Russia.

Author

Cheprasov, Maksim Yu., Boeskorov, Gennady G., Novgorodov, Gavril P., Tikhonov, Alexei N., Grigorieva, Lena V., Boulygina, Eugenia S., Slobodova, Natalia V., Sharko, Fedor S., Protopopov, Albert V., and Nedoluzhko, Artem V.

Subjects
*BROWN bear, *HOLOCENE Epoch, *ISLANDS, *DNA sequencing, *PLEISTOCENE Epoch, *DNA fingerprinting, *TUNDRAS
Abstract

The brown bear (Ursus arctos L., 1758) is a widespread bear species inhabiting the forest zone of Eurasia, including the Republic of Yakutia. The association with forest habitats explains why the Pleistocene findings of U. arctos fossils are rare in the northern part of Eastern Siberia, where open steppe-tundra and steppefied landscapes prevailed during the Pleistocene. Fossils of U. arctos that have been found on the territory of Yakutia are dated since the beginning of the Middle Pleistocene. These are mainly the skulls and bones of the postcranial skeleton. In the present study, using comparative morphological analysis, computed tomography, and DNA sequencing, we describe a first mummified carcass of a brown bear individual that inhabited the New Siberian Islands (Northeast Siberia) in the Middle Holocene, approximately 3,500 years BP, which was found in the permafrost of Bolshoy Lyakhovsky Island, Russia, in 2020. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Mitochondrial genome of Megaphragma amalphitanum (Hymenoptera: Trichogrammatidae).

Author

Nedoluzhko, Artem V., Sharko, Fedor S., Boulygina, Eugenia S., Tsygankova, Svetlana V., Sokolov, Alexey S., Mazur, Alexander M., Polilov, Alexey A., Prokhortchouk, Egor B., and Skryabin, Konstantin G.

Subjects
TRICHOGRAMMATIDAE, INSECTS, MITOCHONDRIAL DNA, INSECT phylogeny, TRANSFER RNA, RIBOSOMAL RNA
Abstract

The mitochondrial genome of the parasitic waspMegaphragma amalphitanumis published in this paper. The mitochondrial DNA (mtDNA) is 15 041 base pairs (bp) in length and contained 13 protein-coding genes, 2 rRNA genes and 22 tRNA genes. The overall base composition of the genome in descending order was 45.67% A, 8.71% C, 39.63% T and 5.99% G, with a significant AT bias of 85.30%. [ABSTRACT FROM AUTHOR]

Published
2016
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32. Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

Author

Purdue, Mark P., Johansson, Mattias, Zelenika, Diana, Toro, Jorge R., Scelo, Ghislaine, Moore, Lee E., Prokhortchouk, Egor, Wu, Xifeng, Kiemeney, Lambertus A., Gaborieau, Valerie, Jacobs, Kevin B., Allen, Naomi E., Bueno de Mesquita, H. Bas, Peeters, Petra H. M., Trichopoulos, Dimitrios, Linseisen, Jakob, Ljungberg, Börje, Overvad, Kim, Tjønneland, Anne, Romieu, Isabelle, Riboli, Elio, Mukeria, Anush, Shangina, Oxana, Stevens, Victoria L., Thun, Michael J., Diver, W. Ryan, Gapstur, Susan M., Pharoah, Paul D. P., Easton, Douglas F., Albanes, Demetrius, Weinstein, Stephanie J., Virtamo, Jarmo, Vatten, Lars, Hveem, Kristian, Njølstad, Inger, Tell, Grethe, Stoltenberg, Camilla, Kumar, Rajiv, Koppova, Kvetoslava, Cussenot, Olivier, Benhamou, Simone, Oosterwijk, Egbert, Vermeulen, Sita H., Aben, Katja K., van der Marel, Saskia L., Ye, Yuanqing, Wood, Christopher G., Pu, Xia, Mazur, Alexander M., Boulygina, Eugenia S., Chekanov, Nikolai N., Foglio, Mario, Lechner, Doris, Gut, Ivo, Heath, Simon, Blanche, Hélène, Hutchinson, Amy, Thomas, Gilles, Wang, Zhaoming, Yeager, Meredith, Fraumeni, Joseph F., Skryabin, Konstantin G., McKay, James D., Rothman, Nathaniel, Chanock, Stephen J., Lathrop, Mark, Brennan, Paul, Chow, Wong-Ho, Zaridze, David, Matveev, Vsevolod, Lubinski, Jan, Trubicka, Joanna, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Rudnai, Péter, Fabianova, Eleonora, Bucur, Alexandru, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Boffetta, Paolo, Colt, Joanne S., Davis, Faith G., Schwartz, Kendra L., Banks, Rosamonde E., Selby, Peter J., Harnden, Patricia, Berg, Christine D., Hsing, Ann W., Grubb III, Robert L., Boeing, Heiner, Vineis, Paolo, Clavel-Chapelon, Françoise, Palli, Domenico, Tumino, Rosario, Krogh, Vittorio, Panico, Salvatore, Duell, Eric J., Quirós, J. Ramón, Sánchez, María José, Navarro, Carmen, Ardanaz, Eva, Dorronsoro, Miren, and Khaw, Kay-Tee

Subjects
Genòmica, Kidney cancer, Genomics, Càncer de ronyó
Abstract

We conducted a two-stage genome-wide association study of renal cell carcinoma (RCC) in 3,772 affected individuals (cases) and 8,505 controls of European background from 11 studies and followed up 6 SNPs in 3 replication studies of 2,198 cases and 4,918 controls. Two loci on the regions of 2p21 and 11q13.3 were associated with RCC susceptibility below genome-wide significance. Two correlated variants (r(2) = 0.99 in controls), rs11894252 (P = 1.8 x 10(-8)) and rs7579899 (P = 2.3 x 10(-9)), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC. The second locus, rs7105934, at 11q13.3, contains no characterized genes (P = 7.8 x 10(-14)). In addition, we observed a promising association on 12q24.31 for rs4765623, which maps to SCARB1, the scavenger receptor class B, member 1 gene (P = 2.6 x 10(-8)). Our study reports previously unidentified genomic regions associated with RCC risk that may lead to new etiological insights.

33. Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

Author

Purdue MP, Johansson M, Zelenika D, Toro JR, Scelo G, Moore LE, Prokhortchouk E, Wu X, Kiemeney LA, Gaborieau V, Jacobs KB, Chow WH, Zaridze D, Matveev V, Lubinski J, Trubicka J, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Bucur A, Bencko V, Foretova L, Janout V, Boffetta P, Colt JS, Davis FG, Schwartz KL, Banks RE, Selby PJ, Harnden P, Berg CD, Hsing AW, Grubb RL 3rd, Boeing H, Vineis P, Clavel-Chapelon F, Palli D, Tumino R, Krogh V, Panico S, Duell EJ, Quirós JR, Sanchez MJ, Navarro C, Ardanaz E, Dorronsoro M, Khaw KT, Allen NE, Bueno-de-Mesquita HB, Peeters PH, Trichopoulos D, Linseisen J, Ljungberg B, Overvad K, Tjønneland A, Romieu I, Riboli E, Mukeria A, Shangina O, Stevens VL, Thun MJ, Diver WR, Gapstur SM, Pharoah PD, Easton DF, Albanes D, Weinstein SJ, Virtamo J, Vatten L, Hveem K, Njølstad I, Tell GS, Stoltenberg C, Kumar R, Koppova K, Cussenot O, Benhamou S, Oosterwijk E, Vermeulen SH, Aben KK, van der Marel SL, Ye Y, Wood CG, Pu X, Mazur AM, Boulygina ES, Chekanov NN, Foglio M, Lechner D, Gut I, Heath S, Blanche H, Hutchinson A, Thomas G, Wang Z, Yeager M, Fraumeni JF Jr, Skryabin KG, McKay JD, Rothman N, Chanock SJ, Lathrop M, and Brennan P

Subjects
Case-Control Studies, Genome, Human, Humans, Polymorphism, Single Nucleotide, Risk Factors, Carcinoma, Renal Cell genetics, Chromosomes, Human, Pair 11 genetics, Chromosomes, Human, Pair 2 genetics, Genetic Predisposition to Disease genetics, Genome-Wide Association Study, Kidney Neoplasms genetics
Abstract

We conducted a two-stage genome-wide association study of renal cell carcinoma (RCC) in 3,772 affected individuals (cases) and 8,505 controls of European background from 11 studies and followed up 6 SNPs in 3 replication studies of 2,198 cases and 4,918 controls. Two loci on the regions of 2p21 and 11q13.3 were associated with RCC susceptibility below genome-wide significance. Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC. The second locus, rs7105934, at 11q13.3, contains no characterized genes (P = 7.8 × 10⁻¹⁴). In addition, we observed a promising association on 12q24.31 for rs4765623, which maps to SCARB1, the scavenger receptor class B, member 1 gene (P = 2.6 × 10⁻⁸). Our study reports previously unidentified genomic regions associated with RCC risk that may lead to new etiological insights.

Published
2011
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34. Bacillus alkalidiazotrophicus sp. nov., a diazotrophic, low salt-tolerant alkaliphile isolated from Mongolian soda soil.

Author

Sorokin ID, Kravchenko IK, Tourova TP, Kolganova TV, Boulygina ES, and Sorokin DY

Subjects
Bacillus chemistry, Bacillus isolation & purification, Bacterial Proteins genetics, DNA, Bacterial genetics, Diaminopimelic Acid chemistry, Fatty Acids chemistry, Genes, Bacterial, Genes, rRNA, Molecular Sequence Data, Mongolia, Nitrogen Fixation, Oxidoreductases genetics, Phenotype, Phylogeny, RNA, Ribosomal, 16S genetics, Sequence Analysis, DNA, Sodium Bicarbonate, Bacillus classification, Bacillus genetics, Soil Microbiology
Abstract

Strain MS 6(T) was obtained from a microoxic enrichment with a soda soil sample from north-eastern Mongolia in nitrogen-free alkaline medium at pH 10. The isolate had clostridia-like motile cells and formed ellipsoid endospores. It was able to fix dinitrogen gas growing on nitrogen-free alkaline medium. Strain MS 6(T) was a strictly fermentative bacterium without a respiratory chain, although it had a high catalase activity and tolerated aerobic conditions. It was an obligate alkaliphile with a pH range for growth between 7.5 and 10.6 (optimum at 9.0-9.5). Growth and nitrogen fixation at pH 10 were possible at a total salt content of up to 1.2 M Na(+) (optimum at 0.2-0.3 M). The dominant cellular fatty acids included C(16 : 0), C(16 : 1)omega7, anteiso-C(15 : 0) and C(14 : 0). The dominant isoprenoid quinone was MK-7. The cell-wall peptidoglycan contained meso-diaminopimelic acid as the diagnostic diamino acid. 16S rRNA gene sequencing identified strain MS 6(T) as a member of the genus Bacillus. Its closest relative was Bacillus arseniciselenatis E1H(T). The key functional nitrogenase gene nifH was detected in both strain MS 6(T) and its close relative and these strains formed a novel lineage in the nifH gene family. On the basis of these phenotypic and genetic comparisons, strain MS 6(T) is proposed to represent a novel species of the genus Bacillus, Bacillus alkalidiazotrophicus sp. nov. with the type strain MS 6(T) (=NCCB 100213(T)=UNIQEM U377(T)).

Published
2008
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