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2. Corticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data

Author

Lescure, François-Xavier, Tran, Viet-Thi, Mahévas, Matthieu, Bani-Sadr, Firouze, Robineau, Olivier, Perpoint, Thomas, Perrodeau, Elodie, Gallay, Laure, Ravaud, Philippe, Goehringer, François, Ismaël, Sophie, Laouénan, Cédric, Soulier, Jennifer, Puéchal, Oriane, D’Ortenzio, Eric, Yazdanpanah, Yazdan, Maulin, Laurence, Martinez, Stéphanie, Sanderink, Diane, Fialaire, Pascale, Ansart, Séverine, Perez, Lucas, Destrem, Anne - Laure, Moulin, Chloé, Gicquel, Pascal, Rivière, Frédéric, Martinot, Martin, Zadeh, Mahsa Mohseni, Chroboczek, Tomasz, Belval, Thibaut Challan, Piroth, Lionel, Sixt, Thibault, Moretto, Florian, Cabié, André, Pasquier, Jérémie, Cabras, Ornella, Morrier, Marine, Reuter, Jean, Henin, Thomas, Braquet, Pierre, Desmurs-Clavel, Helene, Hot, Arnaud, Bienvenu, Boris, Asselate, Belkacem, Vignier, Nicolas, Nguala, Steve, Diamantis, Sylvain, Frémont, Guillemette, Nivose, Pierre Louis, Thiébaut, Mathilde, Lefevre, Benjamin, Auge, Hélène, le Turnier, Paul, Benkalfate, Naila, Grossi, Olivier, Pineau, Samuel, Demonchy, Elisa, Merindol, Julie, Durand, Claire, Tieulié, Nathalie, Queyrel, Viviane, Laureillard, Didier, Loubet, Paul, Greffe, Ségolène, Dournon, Nathalie, Kassim, Youssouf Mohamed, Gourjault, Cyrille, Lahens, Alexandre, Legendre, Paul, Morbieu, Caroline, Mahevas, Matthieu, Melica, Giovanna, Levièvre, Jean-Daniel, Schlemmer, Frédéric, Tunesi, Simone, Leblanc, Claire, Bourgarit-Durand, Anne, Bleibtreu, Alexandre, Tebano, Gianpiero, Pacanowski, Jérôme, Zabbe, Jean-Benoit, Devaux, Mathilde, Bellec, Laurent, Gosset-Woimant, Marine, Lambert, Céleste, Hentzien, Maxime, Servettaz, Amélie, Alexandre, Kevin, Etienne, Manuel, Leguillon, Romain, Dollat, Marion, Lefrancois, Rémi, Pouvaret, Anne, Ruch, Yvon, Dieudonné, Yannick, Martin-Blondel, Guillaume, Boumaza, Xavier, Lafaurie, Margaux, Tetart, Macha, Lemaignen, Adrien, Ferreira-Maldent, Nicole, Duréault, Amélie, Gousseff, Marie, Chantepie, Claire, Bisio, Francesca, Pommeret, Fanny, Blamble, Emeline Colomba, and Somohano, Claire Ara

Published
2021
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3. Sotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients

Author

Bruel, Timothée, primary, Vrignaud, Lou-Léna, additional, Porrot, Françoise, additional, Staropoli, Isabelle, additional, Planas, Delphine, additional, Guivel-Benhassine, Florence, additional, Puech, Julien, additional, Prot, Matthieu, additional, Munier, Sandie, additional, Bolland, William Henry, additional, Soulié, Cathia, additional, Zafilaza, Karen, additional, Lusivika-Nzinga, Clovis, additional, Meledge, Marie-Laure, additional, Dorival, Céline, additional, Molino, Diana, additional, Péré, Hélène, additional, Yordanov, Youri, additional, Simon-Lorière, Etienne, additional, Veyer, David, additional, Carrat, Fabrice, additional, Schwartz, Olivier, additional, Marcelin, Anne-Geneviève, additional, Martin-Blondel, Guillaume, additional, Garcia, Magalie, additional, Giraud, Valentin, additional, Metais, Agathe, additional, Cazenave-Roblot, Fance, additional, Martellosio Anne-Marie Ronchetti, Jean-Philippe, additional, Gabas, Thomas, additional, Hadjadj, Naima, additional, Salanoubat, Célia, additional, Chabrol, Amélie, additional, Housset, Pierre, additional, Pardon, Agathe, additional, Faucon, Anne-Laure, additional, Caudwell, Valérie, additional, Roland Liblau, Latifa Hanafi, additional, Alric, Laurent, additional, Pugnet, Grégory, additional, Mourguet, Morgane, additional, Bories, Eva, additional, Bonnet, Delphine, additional, Charpentier, Sandrine, additional, Delobel, Pierre, additional, Debard, Alexa, additional, Beck, Colleen, additional, Boumaza, Xavier, additional, Fanny Lanternier, Stella Rousset, additional, Delage, Claire, additional, Pires, Elisabete Gomes, additional, Cheminant, Morgane, additional, Anthony Chauvin, Nathalie Chavarot, additional, Véronique Delcey Simon Bessis, Xavier Eyer, additional, Cresta, Mélanie, additional, Pélagie Thibaut, Romain Gueneau, additional, Nadal, Marine, additional, Siguier, Martin, additional, Bachir, Marwa, additional, Valérie Pourcher, Christia Palacios, additional, Melenotte, Cléa, additional, Faycal, Antoine, additional, Berot, Vincent, additional, Brin, Cécile, additional, Djebara, Siham, additional, Marot, Stéphane, additional, Sayon, Sophie, additional, Leducq, Vincent, additional, Malet, Isabelle, additional, Teyssou, Elisa, additional, Karine Lacombe, Adélie Gothland, additional, Aad, Yasmine Abi, additional, Chiarabini, Thibault, additional, Feliho, Raynald, additional, Valin, Nadia, additional, Brigant, Fabien, additional, Boize, Julien, additional, Thiébaud, Pierre-Clément, additional, Moreau, Marie, additional, Nathalie De Castro, Charlotte Billard, additional, Liégeon, Geoffroy, additional, Denis, Blandine, additional, Molina, Jean-Michel, additional, André Cabié, Lucia Etheve, additional, Abel, Sylvie, additional, Cabras, Ornella, additional, Guitteaud, Karine, additional, François Vincent Dubee, Sandrine Pierre-, additional, Ndiaye, Diama, additional, Pehlivan, Jonathan, additional, Phelippeau, Michael, additional, Alexandre Duvignaud, Rafael Mahieu, additional, Pistone, Thierry, additional, Desclaux, Arnaud, additional, Neau, Didier, additional, Jean-François Faucher, Charles Cazanave, additional, Festou, Benjamin, additional, Dupuy-Grasset, Magali, additional, Loustaud-Ratti, Véronique, additional, Nathan Peiffer- Smadja, Delphine Chainier, additional, Choquet, Christophe, additional, Da Conceicao, Olivia, additional, Thy, Michael, additional, Collas, Lio, additional, Godard, Cindy, additional, Bouzid, Donia, additional, Ing, Vittiaroat, additional, Pereira, Laurent, additional, Pavlowsky, Thomas, additional, RavautAntoine Asquier-Khati, Camille, additional, Boutoille, David, additional, Chauveau, Marie, additional, Deschanvres, Colin, additional, Audrey Le Bot, François Raffi, additional, Cailleaux, Marine, additional, Benezit, François, additional, Maillard, Anne, additional, Hue, Benoit, additional, François Coustilleres, Pierre Tattevin, additional, Carvalho-Schneider, Claudia, additional, Jamard, Simon, additional, Petit, Laeticia, additional, Natacha Mrozek, Karl Stefic, additional, Theis, Clément, additional, Vidal, Magali, additional, Sauvat, Léo, additional, Benjamin Lefèvre, Delphine Martineau, additional, Baronnet, Guillaume, additional, Florence Ader, Agnès Didier, additional, Perpoint, Thomas, additional, Conrad, Anne, additional, Chabert, Paul, additional, Aurélie Martin, Pierre Chauvelot, additional, Loubet, Paul, additional, Mazet, Julien, additional, Larcher, Romaric, additional, Mathilde Devaux Jérôme Frey, Didier Laureillard, additional, Woerlen, Amos, additional, Remillon, Aline, additional, Absensur-Vuillaume, Laure, additional, Albert Trinh-Duc, Pauline Bouquet, additional, Philippe Petua, Patrick Rispal, additional, Aurore Perrot, Julien Carillo, additional, Delavigne, Karen, additional, Cougoul, Pierre, additional, Dion, Jérémie, additional, Mathieu Blot, Odile Rauzy, additional, Sixt, Thibault, additional, Moretto, Florian, additional, Charles, Carole, additional, Sophie Circosta, Lionel Piroth, additional, Leger, Lydia, additional, Arulananthan, Arulvani, additional, Lascoux, Carine, additional, Valérie, Pascaline, additional, Yazdan Yazdanpanah, Leia Becam, additional, Petrov-Sanchez, Ventzislava, additional, Diallo, Alpha, additional, Le Mestre, Soizic, additional, Le Meut Isabelle Goderel, Guillaume, additional, Chau, Frédéric, additional, Soltana, Brahim, additional, Chane Tang, Jessica, additional, Guedj, Jérémie, additional, and Caille, Yvanie, additional

Published
2023
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5. Sotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients

Author

Garcia, Magalie, Giraud, Valentin, Metais, Agathe, Cazenave-Roblot, Fance, Martellosio Anne-Marie Ronchetti, Jean-Philippe, Gabas, Thomas, Hadjadj, Naima, Salanoubat, Célia, Chabrol, Amélie, Housset, Pierre, Pardon, Agathe, Faucon, Anne-Laure, Caudwell, Valérie, Roland Liblau, Latifa Hanafi, Alric, Laurent, Pugnet, Grégory, Mourguet, Morgane, Bories, Eva, Bonnet, Delphine, Charpentier, Sandrine, Delobel, Pierre, Debard, Alexa, Beck, Colleen, Boumaza, Xavier, Fanny Lanternier, Stella Rousset, Delage, Claire, Pires, Elisabete Gomes, Cheminant, Morgane, Anthony Chauvin, Nathalie Chavarot, Véronique Delcey Simon Bessis, Xavier Eyer, Cresta, Mélanie, Pélagie Thibaut, Romain Gueneau, Nadal, Marine, Siguier, Martin, Bachir, Marwa, Valérie Pourcher, Christia Palacios, Melenotte, Cléa, Faycal, Antoine, Berot, Vincent, Brin, Cécile, Djebara, Siham, Zafilaza, Karen, Marot, Stéphane, Sayon, Sophie, Leducq, Vincent, Malet, Isabelle, Teyssou, Elisa, Karine Lacombe, Adélie Gothland, Aad, Yasmine Abi, Chiarabini, Thibault, Feliho, Raynald, Valin, Nadia, Brigant, Fabien, Boize, Julien, Thiébaud, Pierre-Clément, Moreau, Marie, Nathalie De Castro, Charlotte Billard, Liégeon, Geoffroy, Denis, Blandine, Molina, Jean-Michel, André Cabié, Lucia Etheve, Abel, Sylvie, Cabras, Ornella, Guitteaud, Karine, François Vincent Dubee, Sandrine Pierre, Ndiaye, Diama, Pehlivan, Jonathan, Phelippeau, Michael, Alexandre Duvignaud, Rafael Mahieu, Pistone, Thierry, Desclaux, Arnaud, Neau, Didier, Jean-François Faucher, Charles Cazanave, Festou, Benjamin, Dupuy-Grasset, Magali, Loustaud-Ratti, Véronique, Nathan Peiffer- Smadja, Delphine Chainier, Choquet, Christophe, Da Conceicao, Olivia, Thy, Michael, Collas, Lio, Godard, Cindy, Bouzid, Donia, Ing, Vittiaroat, Pereira, Laurent, Pavlowsky, Thomas, RavautAntoine Asquier-Khati, Camille, Boutoille, David, Chauveau, Marie, Deschanvres, Colin, Audrey Le Bot, François Raffi, Cailleaux, Marine, Benezit, François, Maillard, Anne, Hue, Benoit, François Coustilleres, Pierre Tattevin, Carvalho-Schneider, Claudia, Jamard, Simon, Petit, Laeticia, Natacha Mrozek, Karl Stefic, Theis, Clément, Vidal, Magali, Sauvat, Léo, Benjamin Lefèvre, Delphine Martineau, Baronnet, Guillaume, Florence Ader, Agnès Didier, Perpoint, Thomas, Conrad, Anne, Chabert, Paul, Aurélie Martin, Pierre Chauvelot, Loubet, Paul, Mazet, Julien, Larcher, Romaric, Mathilde Devaux Jérôme Frey, Didier Laureillard, Woerlen, Amos, Remillon, Aline, Absensur-Vuillaume, Laure, Albert Trinh-Duc, Pauline Bouquet, Philippe Petua, Patrick Rispal, Aurore Perrot, Julien Carillo, Delavigne, Karen, Cougoul, Pierre, Dion, Jérémie, Mathieu Blot, Odile Rauzy, Sixt, Thibault, Moretto, Florian, Charles, Carole, Sophie Circosta, Lionel Piroth, Leger, Lydia, Arulananthan, Arulvani, Lascoux, Carine, Valérie, Pascaline, Yazdan Yazdanpanah, Leia Becam, Petrov-Sanchez, Ventzislava, Diallo, Alpha, Le Mestre, Soizic, Le Meut Isabelle Goderel, Guillaume, Chau, Frédéric, Soltana, Brahim, Chane Tang, Jessica, Guedj, Jérémie, Caille, Yvanie, Bruel, Timothée, Vrignaud, Lou-Léna, Porrot, Françoise, Staropoli, Isabelle, Planas, Delphine, Guivel-Benhassine, Florence, Puech, Julien, Prot, Matthieu, Munier, Sandie, Bolland, William Henry, Soulié, Cathia, Lusivika-Nzinga, Clovis, Meledge, Marie-Laure, Dorival, Céline, Molino, Diana, Péré, Hélène, Yordanov, Youri, Simon-Lorière, Etienne, Veyer, David, Carrat, Fabrice, Schwartz, Olivier, Marcelin, Anne-Geneviève, and Martin-Blondel, Guillaume

Published
2023
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7. Progressive Multifocal Leukoencephalopathy Treated by Immune Checkpoint Inhibitors.

Author

Boumaza, Xavier, Bonneau, Baptiste, Roos‐Weil, Damien, Pinnetti, Carmela, Rauer, Sebastian, Nitsch, Louisa, Del Bello, Arnaud, Jelcic, Ilijas, Sühs, Kurt‐Wolfram, Gasnault, Jacques, Goreci, Yasemin, Grauer, Oliver, Gnanapavan, Sharmilee, Wicklein, Rebecca, Lambert, Nicolas, Perpoint, Thomas, Beudel, Martijn, Clifford, David, Sommet, Agnès, and Cortese, Irene

Subjects
*PROGRESSIVE multifocal leukoencephalopathy, *IMMUNE checkpoint inhibitors, *IPILIMUMAB, *TERMINATION of treatment, *HIV, *MAGNETIC resonance imaging
Abstract

Objective: Our aim was to assess the real‐world effectiveness of immune checkpoint inhibitors for treatment of patients with progressive multifocal leukoencephalopathy (PML). Methods: We conducted a multicenter survey compiling retrospective data from 79 PML patients, including 38 published cases and 41 unpublished cases, who received immune checkpoint inhibitors as add‐on to standard of care. One‐year follow‐up data were analyzed to determine clinical outcomes and safety profile. Logistic regression was used to identify variables associated with 1‐year survival. Results: Predisposing conditions included hematological malignancy (n = 38, 48.1%), primary immunodeficiency (n = 14, 17.7%), human immunodeficiency virus/acquired immunodeficiency syndrome (n = 12, 15.2%), inflammatory disease (n = 8, 10.1%), neoplasm (n = 5, 6.3%), and transplantation (n = 2, 2.5%). Pembrolizumab was most commonly used (n = 53, 67.1%). One‐year survival was 51.9% (41/79). PML–immune reconstitution inflammatory syndrome (IRIS) was reported in 15 of 79 patients (19%). Pretreatment expression of programmed cell death‐1 on circulating T cells did not differ between survivors and nonsurvivors. Development of contrast enhancement on follow‐up magnetic resonance imaging at least once during follow‐up (OR = 3.16, 95% confidence interval = 1.20–8.72, p = 0.02) was associated with 1‐year survival. Cerebrospinal fluid JC polyomavirus DNA load decreased significantly by 1‐month follow‐up in survivors compared to nonsurvivors (p < 0.0001). Thirty‐two adverse events occurred among 24 of 79 patients (30.4%), and led to treatment discontinuation in 7 of 24 patients (29.1%). Interpretation: In this noncontrolled retrospective study of patients with PML who were treated with immune checkpoint inhibitors, mortality remains high. Development of inflammatory features or overt PML‐IRIS was commonly observed. This study highlights that use of immune checkpoint inhibitors should be strictly personalized toward characteristics of the individual PML patient. ANN NEUROL 2023;93:257–270 [ABSTRACT FROM AUTHOR]

Published
2023
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8. Corticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data

Author

Tran, Viet-Thi, primary, Mahévas, Matthieu, additional, Bani-Sadr, Firouze, additional, Robineau, Olivier, additional, Perpoint, Thomas, additional, Perrodeau, Elodie, additional, Gallay, Laure, additional, Ravaud, Philippe, additional, Goehringer, François, additional, Lescure, François-Xavier, additional, Tran, Viet-Thi, additional, Ismaël, Sophie, additional, Laouénan, Cédric, additional, Soulier, Jennifer, additional, Puéchal, Oriane, additional, D’Ortenzio, Eric, additional, Yazdanpanah, Yazdan, additional, Maulin, Laurence, additional, Martinez, Stéphanie, additional, Sanderink, Diane, additional, Fialaire, Pascale, additional, Ansart, Séverine, additional, Perez, Lucas, additional, Destrem, Anne - Laure, additional, Moulin, Chloé, additional, Gicquel, Pascal, additional, Rivière, Frédéric, additional, Martinot, Martin, additional, Zadeh, Mahsa Mohseni, additional, Chroboczek, Tomasz, additional, Belval, Thibaut Challan, additional, Piroth, Lionel, additional, Sixt, Thibault, additional, Moretto, Florian, additional, Cabié, André, additional, Pasquier, Jérémie, additional, Cabras, Ornella, additional, Morrier, Marine, additional, Reuter, Jean, additional, Henin, Thomas, additional, Braquet, Pierre, additional, Desmurs-Clavel, Helene, additional, Hot, Arnaud, additional, Bienvenu, Boris, additional, Asselate, Belkacem, additional, Vignier, Nicolas, additional, Nguala, Steve, additional, Diamantis, Sylvain, additional, Frémont, Guillemette, additional, Nivose, Pierre Louis, additional, Thiébaut, Mathilde, additional, Lefevre, Benjamin, additional, Auge, Hélène, additional, le Turnier, Paul, additional, Benkalfate, Naila, additional, Grossi, Olivier, additional, Pineau, Samuel, additional, Demonchy, Elisa, additional, Merindol, Julie, additional, Durand, Claire, additional, Tieulié, Nathalie, additional, Queyrel, Viviane, additional, Laureillard, Didier, additional, Loubet, Paul, additional, Greffe, Ségolène, additional, Dournon, Nathalie, additional, Kassim, Youssouf Mohamed, additional, Gourjault, Cyrille, additional, Lahens, Alexandre, additional, Legendre, Paul, additional, Morbieu, Caroline, additional, Mahevas, Matthieu, additional, Melica, Giovanna, additional, Levièvre, Jean-Daniel, additional, Schlemmer, Frédéric, additional, Tunesi, Simone, additional, Leblanc, Claire, additional, Bourgarit-Durand, Anne, additional, Bleibtreu, Alexandre, additional, Tebano, Gianpiero, additional, Pacanowski, Jérôme, additional, Zabbe, Jean-Benoit, additional, Devaux, Mathilde, additional, Bellec, Laurent, additional, Gosset-Woimant, Marine, additional, Lambert, Céleste, additional, Hentzien, Maxime, additional, Servettaz, Amélie, additional, Alexandre, Kevin, additional, Etienne, Manuel, additional, Leguillon, Romain, additional, Dollat, Marion, additional, Lefrancois, Rémi, additional, Pouvaret, Anne, additional, Ruch, Yvon, additional, Dieudonné, Yannick, additional, Martin-Blondel, Guillaume, additional, Boumaza, Xavier, additional, Lafaurie, Margaux, additional, Tetart, Macha, additional, Lemaignen, Adrien, additional, Ferreira-Maldent, Nicole, additional, Duréault, Amélie, additional, Gousseff, Marie, additional, Chantepie, Claire, additional, Bisio, Francesca, additional, Pommeret, Fanny, additional, Blamble, Emeline Colomba, additional, and Somohano, Claire Ara, additional

Published
2021
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9. Brain abscess caused by Listeria monocytogenes and Toxoplasma gondii.

Author

Goudy, Pierre, Vavasseur, Coline, Boumaza, Xavier, Bryant, Sabrina, Fillaux, Judith, Iriart, Xavier, Grare, Marion, Beltaïfa, Mohamed Yassine, Roux, Franck-Emmanuel, Bonneville, Fabrice, Martin-Blondel, Guillaume, and Geeraerts, Thomas

Subjects
*BRAIN abscess, *LISTERIA monocytogenes, *TOXOPLASMA gondii
Published
2024
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