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1. Results of the COVID-19 mental health international for the health professionals (COMET-HP) study: depression, suicidal tendencies and conspiracism.

Author

Fountoulakis, Konstantinos N, N. Karakatsoulis, Grigorios, Abraham, Seri, Adorjan, Kristina, Ahmed, Helal Uddin, Alarcón, Renato D, Arai, Kiyomi, Auwal, Sani Salihu, Bobes, Julio, Bobes-Bascaran, Teresa, Bourgin-Duchesnay, Julie, Bredicean, Cristina Ana, Bukelskis, Laurynas, Burkadze, Akaki, Cabrera Abud, Indira Indiana, Castilla-Puentes, Ruby, Cetkovich, Marcelo, Colon-Rivera, Hector, Corral, Ricardo, Cortez-Vergara, Carla, Crepin, Piirika, de Berardis, Domenico, Zamora Delgado, Sergio, de Lucena, David, de Sousa, Avinash, di Stefano, Ramona, Dodd, Seetal, Elek, Livia Priyanka, Elissa, Anna, Erdelyi-Hamza, Berta, Erzin, Gamze, Etchevers, Martin J, Falkai, Peter, Farcas, Adriana, Fedotov, Ilya, Filatova, Viktoriia, Fountoulakis, Nikolaos K, Frankova, Iryna, Franza, Francesco, Frias, Pedro, Galako, Tatiana, Garay, Cristian J, Garcia-Álvarez, Leticia, García-Portilla, Paz, Gonda, Xenia, Gondek, Tomasz M, Morera González, Daniela, Gould, Hilary, Grandinetti, Paolo, Grau, Arturo, Groudeva, Violeta, Hagin, Michal, Harada, Takayuki, Hasan, Tasdik M, Azreen Hashim, Nurul, Hilbig, Jan, Hossain, Sahadat, Iakimova, Rossitza, Ibrahim, Mona, Iftene, Felicia, Ignatenko, Yulia, Irarrazaval, Matias, Ismail, Zaliha, Ismayilova, Jamila, Jacobs, Asaf, Jakovljević, Miro, Jakšić, Nenad, Javed, Afzal, Yilmaz Kafali, Helin, Karia, Sagar, Kazakova, Olga, Khalifa, Doaa, Khaustova, Olena, Koh, Steve, Kopishinskaia, Svetlana, Kosenko, Korneliia, Koupidis, Sotirios A, Kovacs, Illes, Kulig, Barbara, Lalljee, Alisha, Liewig, Justine, Majid, Abdul, Malashonkova, Evgeniia, Malik, Khamelia, Iqbal Malik, Najma, Mammadzada, Gulay, Mandalia, Bilvesh, Marazziti, Donatella, Marčinko, Darko, Martinez, Stephanie, Matiekus, Eimantas, Mejia, Gabriela, Memon, Roha Saeed, Meza Martínez, Xarah Elenne, Mickevičiūtė, Dalia, Milev, Roumen, Mohammed, Muftau, Molina-López, Alejandro, and Morozov, Petr

Subjects
Anxiety, COVID-19, Conspiracy theories, Depression, Health professionals, Mental disorders, Mental health, Psychiatry, Suicidality, Humans, Female, Male, Mental Health, Suicidal Ideation, Health Personnel, Brain Disorders, Behavioral and Social Science, Serious Mental Illness, Mind and Body, Prevention, Good Health and Well Being, Clinical Sciences, Psychology, Cognitive Sciences
Abstract

IntroductionThe current study aimed to investigate the rates of anxiety, clinical depression, and suicidality and their changes in health professionals during the COVID-19 outbreak.Materials and methodsThe data came from the larger COMET-G study. The study sample includes 12,792 health professionals from 40 countries (62.40% women aged 39.76 ± 11.70; 36.81% men aged 35.91 ± 11.00 and 0.78% non-binary gender aged 35.15 ± 13.03). Distress and clinical depression were identified with the use of a previously developed cut-off and algorithm, respectively.Statistical analysisDescriptive statistics were calculated. Chi-square tests, multiple forward stepwise linear regression analyses, and Factorial Analysis of Variance (ANOVA) tested relations among variables.ResultsClinical depression was detected in 13.16% with male doctors and 'non-binary genders' having the lowest rates (7.89 and 5.88% respectively) and 'non-binary gender' nurses and administrative staff had the highest (37.50%); distress was present in 15.19%. A significant percentage reported a deterioration in mental state, family dynamics, and everyday lifestyle. Persons with a history of mental disorders had higher rates of current depression (24.64% vs. 9.62%; p

Published
2023

2. The effect of different degrees of lockdown and self-identified gender on anxiety, depression and suicidality during the COVID-19 pandemic: Data from the international COMET-G study.

Author

Fountoulakis, Konstantinos N, Karakatsoulis, Grigorios N, Abraham, Seri, Adorjan, Kristina, Ahmed, Helal Uddin, Alarcón, Renato D, Arai, Kiyomi, Auwal, Sani Salihu, Berk, Michael, Bjedov, Sarah, Bobes, Julio, Bobes-Bascaran, Teresa, Bourgin-Duchesnay, Julie, Bredicean, Cristina Ana, Bukelskis, Laurynas, Burkadze, Akaki, Abud, Indira Indiana Cabrera, Castilla-Puentes, Ruby, Cetkovich, Marcelo, Colon-Rivera, Hector, Corral, Ricardo, Cortez-Vergara, Carla, Crepin, Piirika, De Berardis, Domenico, Delgado, Sergio Zamora, De Lucena, David, De Sousa, Avinash, Stefano, Ramona Di, Dodd, Seetal, Elek, Livia Priyanka, Elissa, Anna, Erdelyi-Hamza, Berta, Erzin, Gamze, Etchevers, Martin J, Falkai, Peter, Farcas, Adriana, Fedotov, Ilya, Filatova, Viktoriia, Fountoulakis, Nikolaos K, Frankova, Iryna, Franza, Francesco, Frias, Pedro, Galako, Tatiana, Garay, Cristian J, Garcia-Álvarez, Leticia, García-Portilla, Maria Paz, Gonda, Xenia, Gondek, Tomasz M, González, Daniela Morera, Gould, Hilary, Grandinetti, Paolo, Grau, Arturo, Groudeva, Violeta, Hagin, Michal, Harada, Takayuki, Hasan, Tasdik M, Hashim, Nurul Azreen, Hilbig, Jan, Hossain, Sahadat, Iakimova, Rossitza, Ibrahim, Mona, Iftene, Felicia, Ignatenko, Yulia, Irarrazaval, Matias, Ismail, Zaliha, Ismayilova, Jamila, Jacobs, Asaf, Jakovljević, Miro, Jakšić, Nenad, Javed, Afzal, Kafali, Helin Yilmaz, Karia, Sagar, Kazakova, Olga, Khalifa, Doaa, Khaustova, Olena, Koh, Steve, Kopishinskaia, Svetlana, Kosenko, Korneliia, Koupidis, Sotirios A, Kovacs, Illes, Kulig, Barbara, Lalljee, Alisha, Liewig, Justine, Majid, Abdul, Malashonkova, Evgeniia, Malik, Khamelia, Malik, Najma Iqbal, Mammadzada, Gulay, Mandalia, Bilvesh, Marazziti, Donatella, Marčinko, Darko, Martinez, Stephanie, Matiekus, Eimantas, Mejia, Gabriela, Memon, Roha Saeed, Martínez, Xarah Elenne Meza, Mickevičiūtė, Dalia, Milev, Roumen, Mohammed, Muftau, and Molina-López, Alejandro

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Prevention, Mental Health, Depression, Brain Disorders, Serious Mental Illness, Mental health, Good Health and Well Being, Anxiety, COVID-19, Communicable Disease Control, Female, Humans, Male, Pandemics, Suicide, Suicidality, lockdown, anxiety, mental health history, Mental health, lockdown, anxiety, mental health history, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Clinical sciences, Clinical and health psychology
Abstract

IntroductionDuring the COVID-19 pandemic various degrees of lockdown were applied by countries around the world. It is considered that such measures have an adverse effect on mental health but the relationship of measure intensity with the mental health effect has not been thoroughly studied. Here we report data from the larger COMET-G study pertaining to this question.Material and methodsDuring the COVID-19 pandemic, data were gathered with an online questionnaire from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.61; 34.05% males aged 34.90±13.29 and 1.10% other aged 31.64±13.15). Anxiety was measured with the STAI, depression with the CES-D and suicidality with the RASS. Distress and probable depression were identified with the use of a previously developed cut-off and algorithm respectively.Statistical analysisIt included the calculation of Relative Risk (RR), Factorial ANOVA and Multiple backwards stepwise linear regression analysis RESULTS: Approximately two-thirds were currently living under significant restrictions due to lockdown. For both males and females the risk to develop clinical depression correlated significantly with each and every level of increasing lockdown degree (RR 1.72 and 1.90 respectively). The combined lockdown and psychiatric history increased RR to 6.88 The overall relationship of lockdown with severity of depression, though significant was small.ConclusionsThe current study is the first which reports an almost linear relationship between lockdown degree and effect in mental health. Our findings, support previous suggestions concerning the need for a proactive targeted intervention to protect mental health more specifically in vulnerable groups.

Published
2022

3. Results of the COVID-19 mental health international for the health professionals (COMET-HP) study: depression, suicidal tendencies and conspiracism

Author

N. Fountoulakis, Konstantinos, N. Karakatsoulis, Grigorios, Abraham, Seri, Adorjan, Kristina, Ahmed, Helal Uddin, Alarcón, Renato D., Arai, Kiyomi, Auwal, Sani Salihu, Bobes, Julio, Bobes-Bascaran, Teresa, Bourgin-Duchesnay, Julie, Bredicean, Cristina Ana, Bukelskis, Laurynas, Burkadze, Akaki, Cabrera Abud, Indira Indiana, Castilla-Puentes, Ruby, Cetkovich, Marcelo, Colon-Rivera, Hector, Corral, Ricardo, Cortez-Vergara, Carla, Crepin, Piirika, de Berardis, Domenico, Zamora Delgado, Sergio, de Lucena, David, de Sousa, Avinash, di Stefano, Ramona, Dodd, Seetal, Elek, Livia Priyanka, Elissa, Anna, Erdelyi-Hamza, Berta, Erzin, Gamze, Etchevers, Martin J., Falkai, Peter, Farcas, Adriana, Fedotov, Ilya, Filatova, Viktoriia, Fountoulakis, Nikolaos K., Frankova, Iryna, Franza, Francesco, Frias, Pedro, Galako, Tatiana, Garay, Cristian J., Garcia-Álvarez, Leticia, García-Portilla, Paz, Gonda, Xenia, Gondek, Tomasz M., Morera González, Daniela, Gould, Hilary, Grandinetti, Paolo, Grau, Arturo, Groudeva, Violeta, Hagin, Michal, Harada, Takayuki, Hasan, Tasdik M., Azreen Hashim, Nurul, Hilbig, Jan, Hossain, Sahadat, Iakimova, Rossitza, Ibrahim, Mona, Iftene, Felicia, Ignatenko, Yulia, Irarrazaval, Matias, Ismail, Zaliha, Ismayilova, Jamila, Jacobs, Asaf, Jakovljević, Miro, Jakšić, Nenad, Javed, Afzal, Yilmaz Kafali, Helin, Karia, Sagar, Kazakova, Olga, Khalifa, Doaa, Khaustova, Olena, Koh, Steve, Kopishinskaia, Svetlana, Kosenko, Korneliia, Koupidis, Sotirios A., Kovacs, Illes, Kulig, Barbara, Lalljee, Alisha, Liewig, Justine, Majid, Abdul, Malashonkova, Evgeniia, Malik, Khamelia, Iqbal Malik, Najma, Mammadzada, Gulay, Mandalia, Bilvesh, Marazziti, Donatella, Marčinko, Darko, Martinez, Stephanie, Matiekus, Eimantas, Mejia, Gabriela, Memon, Roha Saeed, Meza Martínez, Xarah Elenne, Mickevičiūtė, Dalia, Milev, Roumen, Mohammed, Muftau, Molina-López, Alejandro, Morozov, Petr, Muhammad, Nuru Suleiman, Mustač, Filip, Naor, Mika S., Nassieb, Amira, Navickas, Alvydas, Okasha, Tarek, Pandova, Milena, Panfil, Anca-Livia, Panteleeva, Liliya, Papava, Ion, Patsali, Mikaella E., Pavlichenko, Alexey, Pejuskovic, Bojana, Pinto da Costa, Mariana, Popkov, Mikhail, Popovic, Dina, Raduan, Nor Jannah Nasution, Vargas Ramírez, Francisca, Rancans, Elmars, Razali, Salmi, Rebok, Federico, Rewekant, Anna, Reyes Flores, Elena Ninoska, Rivera-Encinas, María Teresa, Saiz, Pilar A., Sánchez de Carmona, Manuel, Saucedo Martínez, David, Saw, Jo Anne, Saygili, Görkem, Schneidereit, Patricia, Shah, Bhumika, Shirasaka, Tomohiro, Silagadze, Ketevan, Sitanggang, Satti, Skugarevsky, Oleg, Spikina, Anna, Mahalingappa, Sridevi Sira, Stoyanova, Maria, Szczegielniak, Anna, Tamasan, Simona Claudia, Tavormina, Giuseppe, Tavormina, Maurilio Giuseppe Maria, Theodorakis, Pavlos N., Tohen, Mauricio, Tsapakis, Eva-Maria, Tukhvatullina, Dina, Ullah, Irfan, Vaidya, Ratnaraj, Vega-Dienstmaier, Johann M., Vrublevska, Jelena, Vukovic, Olivera, Vysotska, Olga, Widiasih, Natalia, Yashikhina, Anna, Prezerakos, Panagiotis E., Berk, Michael, Levaj, Sarah, and Smirnova, Daria

Published
2023
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4. Results of the COVID-19 mental health international for the general population (COMET-G) study

Author

Fountoulakis, Konstantinos N, Karakatsoulis, Grigorios, Abraham, Seri, Adorjan, Kristina, Ahmed, Helal Uddin, Alarcón, Renato D, Arai, Kiyomi, Auwal, Sani Salihu, Berk, Michael, Bjedov, Sarah, Bobes, Julio, Bobes-Bascaran, Teresa, Bourgin-Duchesnay, Julie, Bredicean, Cristina Ana, Bukelskis, Laurynas, Burkadze, Akaki, Abud, Indira Indiana Cabrera, Castilla-Puentes, Ruby, Cetkovich, Marcelo, Colon-Rivera, Hector, Corral, Ricardo, Cortez-Vergara, Carla, Crepin, Piirika, De Berardis, Domenico, Zamora Delgado, Sergio, De Lucena, David, De Sousa, Avinash, Stefano, Ramona Di, Dodd, Seetal, Elek, Livia Priyanka, Elissa, Anna, Erdelyi-Hamza, Berta, Erzin, Gamze, Etchevers, Martin J, Falkai, Peter, Farcas, Adriana, Fedotov, Ilya, Filatova, Viktoriia, Fountoulakis, Nikolaos K, Frankova, Iryna, Franza, Francesco, Frias, Pedro, Galako, Tatiana, Garay, Cristian J, Garcia-Álvarez, Leticia, García-Portilla, Maria Paz, Gonda, Xenia, Gondek, Tomasz M, González, Daniela Morera, Gould, Hilary, Grandinetti, Paolo, Grau, Arturo, Groudeva, Violeta, Hagin, Michal, Harada, Takayuki, Hasan, M Tasdik, Hashim, Nurul Azreen, Hilbig, Jan, Hossain, Sahadat, Iakimova, Rossitza, Ibrahim, Mona, Iftene, Felicia, Ignatenko, Yulia, Irarrazaval, Matias, Ismail, Zaliha, Ismayilova, Jamila, Jacobs, Asaf, Jakovljević, Miro, Jakšić, Nenad, Javed, Afzal, Kafali, Helin Yilmaz, Karia, Sagar, Kazakova, Olga, Khalifa, Doaa, Khaustova, Olena, Koh, Steve, Kopishinskaia, Svetlana, Kosenko, Korneliia, Koupidis, Sotirios A, Kovacs, Illes, Kulig, Barbara, Lalljee, Alisha, Liewig, Justine, Majid, Abdul, Malashonkova, Evgeniia, Malik, Khamelia, Malik, Najma Iqbal, Mammadzada, Gulay, Mandalia, Bilvesh, Marazziti, Donatella, Marčinko, Darko, Martinez, Stephanie, Matiekus, Eimantas, Mejia, Gabriela, Memon, Roha Saeed, Martínez, Xarah Elenne Meza, Mickevičiūtė, Dalia, Milev, Roumen, Mohammed, Muftau, and Molina-López, Alejandro

Subjects
Mind and Body, Mental Health, Brain Disorders, Serious Mental Illness, Prevention, Depression, Behavioral and Social Science, Mental health, Good Health and Well Being, Adult, Anxiety, COVID-19, Female, Global Burden of Disease, Humans, Male, Middle Aged, Pandemics, SARS-CoV-2, Stress, Psychological, Suicidal Ideation, Suicidality, Conspiracy theories, Mental disorders, Psychiatry, Medical and Health Sciences, Psychology and Cognitive Sciences
Abstract

IntroductionThere are few published empirical data on the effects of COVID-19 on mental health, and until now, there is no large international study.Material and methodsDuring the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.61; 34.05% males aged 34.90±13.29 and 1.10% other aged 31.64±13.15). Distress and probable depression were identified with the use of a previously developed cut-off and algorithm respectively.Statistical analysisDescriptive statistics were calculated. Chi-square tests, multiple forward stepwise linear regression analyses and Factorial Analysis of Variance (ANOVA) tested relations among variables.ResultsProbable depression was detected in 17.80% and distress in 16.71%. A significant percentage reported a deterioration in mental state, family dynamics and everyday lifestyle. Persons with a history of mental disorders had higher rates of current depression (31.82% vs. 13.07%). At least half of participants were accepting (at least to a moderate degree) a non-bizarre conspiracy. The highest Relative Risk (RR) to develop depression was associated with history of Bipolar disorder and self-harm/attempts (RR = 5.88). Suicidality was not increased in persons without a history of any mental disorder. Based on these results a model was developed.ConclusionsThe final model revealed multiple vulnerabilities and an interplay leading from simple anxiety to probable depression and suicidality through distress. This could be of practical utility since many of these factors are modifiable. Future research and interventions should specifically focus on them.

Published
2022

5. Non-binary gender, vulnerable populations and mental health during the COVID-19 pandemic: Data from the COVID-19 MEntal health inTernational for the general population (COMET-G) study

Author

Fountoulakis, Konstantinos N., Vrublevska, Jelena, Abraham, Seri, Adorjan, Kristina, Ahmed, Helal Uddin, Alarcón, Renato D., Arai, Kiyomi, Auwal, Sani Salihu, Berk, Michael, Bjedov, Sarah, Bobes, Julio, Bobes-Bascaran, Teresa, Bourgin-Duchesnay, Julie, Bredicean, Cristina Ana, Bukelskis, Laurynas, Burkadze, Akaki, Abud, Indira Indiana Cabrera, Castilla-Puentes, Ruby, Cetkovich, Marcelo, Colon-Rivera, Hector, Corral, Ricardo, Cortez-Vergara, Carla, Crepin, Piirika, De Berardis, Domenico, Delgado, Sergio Zamora, De Lucena, David, De Sousa, Avinash, Di Stefano, Ramona, Dodd, Seetal, Elek, Livia Priyanka, Elissa, Anna, Erdelyi-Hamza, Berta, Erzin, Gamze, Etchevers, Martin J., Falkai, Peter, Farcas, Adriana, Fedotov, Ilya, Filatova, Viktoriia, Fountoulakis, Nikolaos K., Frankova, Iryna, Franza, Francesco, Frias, Pedro, Galako, Tatiana, Garay, Cristian J., Garcia-Álvarez, Leticia, García-Portilla, Maria Paz, Gonda, Xenia, Gondek, Tomasz M., González, Daniela Morera, Gould, Hilary, Grandinetti, Paolo, Grau, Arturo, Groudeva, Violeta, Hagin, Michal, Harada, Takayuki, Hasan, Tasdik M., Hashim, Nurul Azreen, Hilbig, Jan, Hossain, Sahadat, Iakimova, Rossitza, Ibrahim, Mona, Iftene, Felicia, Ignatenko, Yulia, Irarrazaval, Matias, Ismail, Zaliha, Ismayilova, Jamila, Jacobs, Asaf, Jakovljević, Miro, Jakšić, Nenad, Javed, Afzal, Kafali, Helin Yilmaz, Karia, Sagar, Kazakova, Olga, Khalifa, Doaa, Khaustova, Olena, Koh, Steve, Kosenko, Korneliia, Koupidis, Sotirios A., Lalljee, Alisha, Liewig, Justine, Majid, Abdul, Malashonkova, Evgeniia, Malik, Khamelia, Malik, Najma Iqbal, Mammadzada, Gulay, Mandalia, Bilvesh, Marazziti, Donatella, Marčinko, Darko, Martinez, Stephanie, Matiekus, Eimantas, Mejia, Gabriela, Memon, Roha Saeed, Martínez, Xarah Elenne Meza, Mickevičiūtė, Dalia, Milev, Roumen, Mohammed, Muftau, Molina-López, Alejandro, Morozov, Petr, Muhammad, Nuru Suleiman, Mustač, Filip, Naor, Mika S., Nassieb, Amira, Navickas, Alvydas, Okasha, Tarek, Pandova, Milena, Panfil, Anca-Livia, Panteleeva, Liliya, Papava, Ion, Patsali, Mikaella E., Pavlichenko, Alexey, Pejuskovic, Bojana, Da Costa, Mariana Pinto, Popkov, Mikhail, Popovic, Dina, Raduan, Nor Jannah Nasution, Ramírez, Francisca Vargas, Rancans, Elmars, Razali, Salmi, Rebok, Federico, Rewekant, Anna, Flores, Elena Ninoska Reyes, Rivera-Encinas, María Teresa, Saiz, Pilar, de Carmona, Manuel Sánchez, Martínez, David Saucedo, Saw, Jo Anne, Saygili, Görkem, Schneidereit, Patricia, Shah, Bhumika, Shirasaka, Tomohiro, Silagadze, Ketevan, Sitanggang, Satti, Skugarevsky, Oleg, Spikina, Anna, Mahalingappa, Sridevi Sira, Stoyanova, Maria, Szczegielniak, Anna, Tamasan, Simona Claudia, Tavormina, Giuseppe, Tavormina, Maurilio Giuseppe Maria, Theodorakis, Pavlos N., Tohen, Mauricio, Tsapakis, Eva Maria, Tukhvatullina, Dina, Ullah, Irfan, Vaidya, Ratnaraj, Vega-Dienstmaier, Johann M., Vukovic, Olivera, Vysotska, Olga, Widiasih, Natalia, Yashikhina, Anna, and Smirnova, Daria

Published
2024
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6. The effect of different degrees of lockdown and self-identified gender on anxiety, depression and suicidality during the COVID-19 pandemic: Data from the international COMET-G study.

Author

Fountoulakis, Konstantinos N., Karakatsoulis, Grigorios N., Abraham, Seri, Adorjan, Kristina, Ahmed, Helal Uddin, Alarcón, Renato D., Arai, Kiyomi, Auwal, Sani Salihu, Berk, Michael, Bjedov, Sarah, Bobes, Julio, Bobes-Bascaran, Teresa, Bourgin-Duchesnay, Julie, Bredicean, Cristina Ana, Bukelskis, Laurynas, Burkadze, Akaki, Abud, Indira Indiana Cabrera, Castilla-Puentes, Ruby, Cetkovich, Marcelo, Colon-Rivera, Hector, Corral, Ricardo, Cortez-Vergara, Carla, Crepin, Piirika, De Berardis, Domenico, Delgado, Sergio Zamora, De Lucena, David, De Sousa, Avinash, Stefano, Ramona Di, Dodd, Seetal, Elek, Livia Priyanka, Elissa, Anna, Erdelyi-Hamza, Berta, Erzin, Gamze, Etchevers, Martin J., Falkai, Peter, Farcas, Adriana, Fedotov, Ilya, Filatova, Viktoriia, Fountoulakis, Nikolaos K., Frankova, Iryna, Franza, Francesco, Frias, Pedro, Galako, Tatiana, Garay, Cristian J., Garcia-Álvarez, Leticia, García-Portilla, Maria Paz, Gonda, Xenia, Gondek, Tomasz M., González, Daniela Morera, Gould, Hilary, Grandinetti, Paolo, Grau, Arturo, Groudeva, Violeta, Hagin, Michal, Harada, Takayuki, Hasan, Tasdik M., Hashim, Nurul Azreen, Hilbig, Jan, Hossain, Sahadat, Iakimova, Rossitza, Ibrahim, Mona, Iftene, Felicia, Ignatenko, Yulia, Irarrazaval, Matias, Ismail, Zaliha, Ismayilova, Jamila, Jacobs, Asaf, Jakovljević, Miro, Jakšić, Nenad, Javed, Afzal, Kafali, Helin Yilmaz, Karia, Sagar, Kazakova, Olga, Khalifa, Doaa, Khaustova, Olena, Koh, Steve, Kopishinskaia, Svetlana, Kosenko, Korneliia, Koupidis, Sotirios A., Kovacs, Illes, Kulig, Barbara, Lalljee, Alisha, Liewig, Justine, Majid, Abdul, Malashonkova, Evgeniia, Malik, Khamelia, Malik, Najma Iqbal, Mammadzada, Gulay, Mandalia, Bilvesh, Marazziti, Donatella, Marčinko, Darko, Martinez, Stephanie, Matiekus, Eimantas, Mejia, Gabriela, Memon, Roha Saeed, Martínez, Xarah Elenne Meza, Mickevičiūtė, Dalia, Milev, Roumen, Mohammed, Muftau, Molina-López, Alejandro, Morozov, Petr, Muhammad, Nuru Suleiman, Mustač, Filip, Naor, Mika S., Nassieb, Amira, Navickas, Alvydas, Okasha, Tarek, Pandova, Milena, Panfil, Anca-Livia, Panteleeva, Liliya, Papava, Ion, Patsali, Mikaella E., Pavlichenko, Alexey, Pejuskovic, Bojana, Da Costa, Mariana Pinto, Popkov, Mikhail, Popovic, Dina, Raduan, Nor Jannah Nasution, Ramírez, Francisca Vargas, Rancans, Elmars, Razali, Salmi, Rebok, Federico, Rewekant, Anna, Flores, Elena Ninoska Reyes, Rivera-Encinas, María Teresa, Saiz, Pilar, de Carmona, Manuel Sánchez, Martínez, David Saucedo, Saw, Jo Anne, Saygili, Görkem, Schneidereit, Patricia, Shah, Bhumika, Shirasaka, Tomohiro, Silagadze, Ketevan, Sitanggang, Satti, Skugarevsky, Oleg, Spikina, Anna, Mahalingappa, Sridevi Sira, Stoyanova, Maria, Szczegielniak, Anna, Tamasan, Simona Claudia, Tavormina, Giuseppe, Tavormina, Maurilio Giuseppe Maria, Theodorakis, Pavlos N., Tohen, Mauricio, Tsapakis, Eva Maria, Tukhvatullina, Dina, Ullah, Irfan, Vaidya, Ratnaraj, Vega-Dienstmaier, Johann M., Vrublevska, Jelena, Vukovic, Olivera, Vysotska, Olga, Widiasih, Natalia, Yashikhina, Anna, Prezerakos, Panagiotis E., and Smirnova, Daria

Published
2022
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7. Cognitive impairment in the schizophrenia spectrum: exploring the relationships of the g-factor with sociodemography, psychopathology, neurodevelopment, and genetics.

Author

Yeh, Delphine, He, Qin, Krebs, Emma, Iftimovici, Anton, Martinez, Gilles, Bourgin-Duchesnay, Julie, Mouaffak, Fayçal, Danset-Alexandre, Charlotte, Gasquet, Marie de, Jantac, Célia, Bendjemaa, Narjes, Chaumette, Boris, Krebs, Marie-Odile, and Scoriels, Linda

Abstract

Background Cognitive impairment constitutes a prevailing issue in the schizophrenia spectrum, severely impacting patients' functional outcomes. A global cognitive score, sensitive to the stages of the spectrum, would benefit the exploration of potential factors involved in the cognitive decline. Methods First, we performed principal component analysis on cognitive scores from 768 individuals across the schizophrenia spectrum, including first-degree relatives of patients, individuals at ultra-high risk, who had a first-episode psychosis, and chronic schizophrenia patients, alongside 124 healthy controls. The analysis provided 10 g-factors as global cognitive scores, validated through correlations with intelligence quotient and assessed for their sensitivity to the stages on the spectrum using analyses of variance. Second, using the g-factors, we explored potential mechanisms underlying cognitive impairment in the schizophrenia spectrum using correlations with sociodemographic, clinical, and developmental data, and linear regressions with genotypic data, pooled through meta-analyses. Results The g-factors were highly correlated with intelligence quotient and with each other, confirming their validity. They presented significant differences between subgroups along the schizophrenia spectrum. They were positively correlated with educational attainment and the polygenic risk score (PRS) for cognitive performance, and negatively correlated with general psychopathology of schizophrenia, neurodevelopmental load, and the PRS for schizophrenia. Conclusions The g-factors appeared as valid estimators of global cognition, enabling discerning cognitive states within the schizophrenia spectrum. Educational attainment and genetics related to cognitive performance may have a positive influence on cognitive functioning, while general psychopathology of schizophrenia, neurodevelopmental load, and genetic liability to schizophrenia may have an adverse impact. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Somatic multicomorbidity and disability in patients with psychiatric disorders in comparison to the general population: a quasi-epidemiological investigation in 54,826 subjects from 40 countries (COMET-G study)

Author

Fountoulakis, Konstantinos N., primary, Karakatsoulis, Grigorios N., additional, Abraham, Seri, additional, Adorjan, Kristina, additional, Ahmed, Helal Uddin, additional, Alarcón, Renato D., additional, Arai, Kiyomi, additional, Auwal, Sani Salihu, additional, Berk, Michael, additional, Bjedov, Sarah, additional, Bobes, Julio, additional, Bobes-Bascaran, Teresa, additional, Bourgin-Duchesnay, Julie, additional, Bredicean, Cristina Ana, additional, Bukelskis, Laurynas, additional, Burkadze, Akaki, additional, Cabrera Abud, Indira Indiana, additional, Castilla-Puentes, Ruby, additional, Cetkovich, Marcelo, additional, Colon-Rivera, Hector, additional, Corral, Ricardo, additional, Cortez-Vergara, Carla, additional, Crepin, Piirika, additional, De Berardis, Domenico, additional, Zamora Delgado, Sergio, additional, Lucena, David De, additional, Sousa, Avinash De, additional, Stefano, Ramona Di, additional, Dodd, Seetal, additional, Priyanka Elek, Livia, additional, Elissa, Anna, additional, Erdelyi-Hamza, Berta, additional, Erzin, Gamze, additional, Etchevers, Martin J., additional, Falkai, Peter, additional, Farcas, Adriana, additional, Fedotov, Ilya, additional, Filatova, Viktoriia, additional, Fountoulakis, Nikolaos K., additional, Frankova, Iryna, additional, Franza, Francesco, additional, Frias, Pedro, additional, Galako, Tatiana, additional, Garay, Cristian J., additional, Garcia-Álvarez, Leticia, additional, García-Portilla, Maria Paz, additional, Gonda, Xenia, additional, Gondek, Tomasz M., additional, Morera González, Daniela, additional, Gould, Hilary, additional, Grandinetti, Paolo, additional, Grau, Arturo, additional, Groudeva, Violeta, additional, Hagin, Michal, additional, Harada, Takayuki, additional, Hasan, Tasdik M., additional, Azreen Hashim, Nurul, additional, Hilbig, Jan, additional, Hossain, Sahadat, additional, Iakimova, Rossitza, additional, Ibrahim, Mona, additional, Iftene, Felicia, additional, Ignatenko, Yulia, additional, Irarrazaval, Matias, additional, Ismail, Zaliha, additional, Ismayilova, Jamila, additional, Jakobs, Asaf, additional, Jakovljević, Miro, additional, Jakšić, Nenad, additional, Javed, Afzal, additional, Kafali, Helin Yilmaz, additional, Karia, Sagar, additional, Kazakova, Olga, additional, Khalifa, Doaa, additional, Khaustova, Olena, additional, Koh, Steve, additional, Kopishinskaia, Svetlana, additional, Kosenko, Korneliia, additional, Koupidis, Sotirios A., additional, Kovacs, Illes, additional, Kulig, Barbara, additional, Lalljee, Alisha, additional, Liewig, Justine, additional, Majid, Abdul, additional, Malashonkova, Evgeniia, additional, Malik, Khamelia, additional, Malik, Najma Iqbal, additional, Mammadzada, Gulay, additional, Mandalia, Bilvesh, additional, Marazziti, Donatella, additional, Marčinko, Darko, additional, Martinez, Stephanie, additional, Matiekus, Eimantas, additional, Mejia, Gabriela, additional, Memon, Roha Saeed, additional, Meza Martínez, Xarah Elenne, additional, Mickevičiūtė, Dalia, additional, Milev, Roumen, additional, Mohammed, Muftau, additional, Molina-López, Alejandro, additional, Morozov, Petr, additional, Muhammad, Nuru Suleiman, additional, Mustač, Filip, additional, Naor, Mika S., additional, Nassieb, Amira, additional, Navickas, Alvydas, additional, Okasha, Tarek, additional, Pandova, Milena, additional, Panfil, Anca-Livia, additional, Panteleeva, Liliya, additional, Papava, Ion, additional, Patsali, Mikaella E., additional, Pavlichenko, Alexey, additional, Pejuskovic, Bojana, additional, Pinto Da Costa, Mariana, additional, Popkov, Mikhail, additional, Popovic, Dina, additional, Raduan, Nor Jannah Nasution, additional, Vargas Ramírez, Francisca, additional, Rancans, Elmars, additional, Razali, Salmi, additional, Rebok, Federico, additional, Rewekant, Anna, additional, Ninoska Reyes Flores, Elena, additional, Rivera-Encinas, María Teresa, additional, Saiz, Pilar, additional, Sánchez de Carmona, Manuel, additional, Saucedo Martínez, David, additional, Saw, Jo Anne, additional, Saygili, Görkem, additional, Schneidereit, Patricia, additional, Shah, Bhumika, additional, Shirasaka, Tomohiro, additional, Silagadze, Ketevan, additional, Sitanggang, Satti, additional, Skugarevsky, Oleg, additional, Spikina, Anna, additional, Mahalingappa, Sridevi Sira, additional, Stoyanova, Maria, additional, Szczegielniak, Anna, additional, Tamasan, Simona Claudia, additional, Tavormina, Giuseppe, additional, Tavormina, Maurilio Giuseppe Maria, additional, Theodorakis, Pavlos N., additional, Tohen, Mauricio, additional, Tsapakis, Eva Maria, additional, Tukhvatullina, Dina, additional, Ullah, Irfan, additional, Vaidya, Ratnaraj, additional, Vega-Dienstmaier, Johann M., additional, Vrublevska, Jelena, additional, Vukovic, Olivera, additional, Vysotska, Olga, additional, Widiasih, Natalia, additional, Yashikhina, Anna, additional, Prezerakos, Panagiotis E., additional, and Smirnova, Daria, additional

Published
2024
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9. Results of the COVID-19 mental health international for the general population (COMET-G) study

Author

Fountoulakis, Konstantinos N, primary, Karakatsoulis, Grigorios, additional, Abraham, Seri, additional, Adorjan, Kristina, additional, Ahmed, Helal Uddin, additional, Alarcón, Renato D., additional, Arai, Kiyomi, additional, Auwal, Sani Salihu, additional, Berk, Michael, additional, Bjedov, Sarah, additional, Bobes, Julio, additional, Bobes-Bascaran, Teresa, additional, Bourgin-Duchesnay, Julie, additional, Bredicean, Cristina Ana, additional, Bukelskis, Laurynas, additional, Burkadze, Akaki, additional, Abud, Indira Indiana Cabrera, additional, Castilla-Puentes, Ruby, additional, Cetkovich, Marcelo, additional, Colon-Rivera, Hector, additional, Corral, Ricardo, additional, Cortez-Vergara, Carla, additional, Crepin, Piirika, additional, De Berardis, Domenico, additional, Zamora Delgado, Sergio, additional, De Lucena, David, additional, De Sousa, Avinash, additional, Stefano, Ramona Di, additional, Dodd, Seetal, additional, Elek, Livia Priyanka, additional, Elissa, Anna, additional, Erdelyi-Hamza, Berta, additional, Erzin, Gamze, additional, Etchevers, Martin J., additional, Falkai, Peter, additional, Farcas, Adriana, additional, Fedotov, Ilya, additional, Filatova, Viktoriia, additional, Fountoulakis, Nikolaos K., additional, Frankova, Iryna, additional, Franza, Francesco, additional, Frias, Pedro, additional, Galako, Tatiana, additional, Garay, Cristian J., additional, Garcia-Álvarez, Leticia, additional, García-Portilla, Maria Paz, additional, Gonda, Xenia, additional, Gondek, Tomasz M., additional, González, Daniela Morera, additional, Gould, Hilary, additional, Grandinetti, Paolo, additional, Grau, Arturo, additional, Groudeva, Violeta, additional, Hagin, Michal, additional, Harada, Takayuki, additional, Hasan, M. Tasdik, additional, Hashim, Nurul Azreen, additional, Hilbig, Jan, additional, Hossain, Sahadat, additional, Iakimova, Rossitza, additional, Ibrahim, Mona, additional, Iftene, Felicia, additional, Ignatenko, Yulia, additional, Irarrazaval, Matias, additional, Ismail, Zaliha, additional, Ismayilova, Jamila, additional, Jacobs, Asaf, additional, Jakovljević, Miro, additional, Jakšić, Nenad, additional, Javed, Afzal, additional, Kafali, Helin Yilmaz, additional, Karia, Sagar, additional, Kazakova, Olga, additional, Khalifa, Doaa, additional, Khaustova, Olena, additional, Koh, Steve, additional, Kopishinskaia, Svetlana, additional, Kosenko, Korneliia, additional, Koupidis, Sotirios A., additional, Kovacs, Illes, additional, Kulig, Barbara, additional, Lalljee, Alisha, additional, Liewig, Justine, additional, Majid, Abdul, additional, Malashonkova, Evgeniia, additional, Malik, Khamelia, additional, Malik, Najma Iqbal, additional, Mammadzada, Gulay, additional, Mandalia, Bilvesh, additional, Marazziti, Donatella, additional, Marčinko, Darko, additional, Martinez, Stephanie, additional, Matiekus, Eimantas, additional, Mejia, Gabriela, additional, Memon, Roha Saeed, additional, Martínez, Xarah Elenne Meza, additional, Mickevičiūtė, Dalia, additional, Milev, Roumen, additional, Mohammed, Muftau, additional, Molina-López, Alejandro, additional, Morozov, Petr, additional, Muhammad, Nuru Suleiman, additional, Mustač, Filip, additional, Naor, Mika S., additional, Nassieb, Amira, additional, Navickas, Alvydas, additional, Okasha, Tarek, additional, Pandova, Milena, additional, Panfil, Anca-Livia, additional, Panteleeva, Liliya, additional, Papava, Ion, additional, Patsali, Mikaella E., additional, Pavlichenko, Alexey, additional, Pejuskovic, Bojana, additional, Pinto Da Costa, Mariana, additional, Popkov, Mikhail, additional, Popovic, Dina, additional, Raduan, Nor Jannah Nasution, additional, Ramírez, Francisca Vargas, additional, Rancans, Elmars, additional, Razali, Salmi, additional, Rebok, Federico, additional, Rewekant, Anna, additional, Flores, Elena Ninoska Reyes, additional, Rivera-Encinas, María Teresa, additional, Saiz, Pilar, additional, de Carmona, Manuel Sánchez, additional, Martínez, David Saucedo, additional, Saw, Jo Anne, additional, Saygili, Görkem, additional, Schneidereit, Patricia, additional, Shah, Bhumika, additional, Shirasaka, Tomohiro, additional, Silagadze, Ketevan, additional, Sitanggang, Satti, additional, Skugarevsky, Oleg, additional, Spikina, Anna, additional, Mahalingappa, Sridevi Sira, additional, Stoyanova, Maria, additional, Szczegielniak, Anna, additional, Tamasan, Simona Claudia, additional, Tavormina, Giuseppe, additional, Tavormina, Maurilio Giuseppe Maria, additional, Theodorakis, Pavlos N., additional, Tohen, Mauricio, additional, Tsapakis, Eva Maria, additional, Tukhvatullina, Dina, additional, Ullah, Irfan, additional, Vaidya, Ratnaraj, additional, Vega-Dienstmaier, Johann M., additional, Vrublevska, Jelena, additional, Vukovic, Olivera, additional, Vysotska, Olga, additional, Widiasih, Natalia, additional, Yashikhina, Anna, additional, Prezerakos, Panagiotis E., additional, and Smirnova, Daria, additional

Published
2022
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10. Dosing antipsychotics in special populations of patients with schizophrenia: severe psychotic agitation, first psychotic episode and elderly patients

Author

Mouaffak, Fayçal, primary, Ferreri, Florian, additional, Bourgin-Duchesnay, Julie, additional, Baloche, Emmanuelle, additional, Blin, Olivier, additional, Vandel, Pierre, additional, Garay, Ricardo P., additional, Vidailhet, Pierre, additional, Corruble, Emmanuelle, additional, and Llorca, Pierre-Michel, additional

Published
2021
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