408 results on '"Bowie, Andrew G."'
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2. SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms
3. Regulation of type I and type III interferon induction in response to pathogen sensing
4. SARM1 regulates NAD+-linked metabolism and select immune genes in macrophages
5. Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores
6. PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
7. Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles
8. Recent insights into innate immune nucleic acid sensing during viral infection
9. Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7
10. Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E.
11. Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration
12. Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO
13. A novel anti-viral role for STAT3 in IFN-α signalling responses
14. Reactive Centre Loop Mutagenesis of SerpinB3 to Target TMPRSS2 and Furin: Inhibition of SARS-CoV-2 Cell Entry and Replication
15. Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
16. Innate immune activation of NFκB and its antagonism by poxviruses
17. A Coding IRAK2 Protein Variant Compromises Toll-like receptor (TLR) Signaling and Is Associated with Colorectal Cancer Survival
18. Innate antiviral signalling in the central nervous system
19. Modulation of Innate Immune Signalling Pathways by Viral Proteins
20. Toll-like receptors as key sensors of viral infection
21. Innate immune detection of microbial nucleic acids
22. SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration
23. Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
24. Self-RNA sentinels signal viral invasion
25. SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration
26. PYHIN Protein Ifi207 Regulates RNA Polymerase II Activity at the Tnf Gene and Contributes to the Establishment of Klebsiella pneumoniae Infection
27. Non‐Canonical Inflammasome Activation Mediates the Adjuvanticity of Nanoparticles
28. CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages
29. Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca 2+ signaling during T cell activation
30. The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons
31. Innate immune sensing of nucleic acids in airway epithelial cells compared to monocytic cells: ID: 103
32. A Frequent Hypofunctional IRAK2 Variant Is Associated With Reduced Spontaneous Hepatitis C Virus Clearance
33. Klebsiella pneumoniaehijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity
34. Next generation SARM1 knockout and epitope tagged CRISPR-Cas9-generated isogenic mice reveal that SARM1 does not participate in regulating nuclear transcription, despite confirmation of protein expression in macrophages
35. DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease
36. The emerging role of human PYHIN proteins in innate immunity: Implications for health and disease
37. The history of Toll-like receptors — redefining innate immunity
38. Role of Toll-Like Receptors in the Innate Immune Response to RNA Viruses
39. List of Contributors
40. Viral Infections and the DNA Sensing Pathway: Lessons from Herpesviruses and Beyond
41. Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration
42. Viral immune modulators perturb the human molecular network by common and unique strategies
43. Rad50 and CARD9, missing links in cytosolic DNA–stimulated inflammation
44. IFI16 is an innate immune sensor for intracellular DNA
45. Viral evasion and subversion of pattern-recognition receptor signalling
46. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
47. The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling
48. RIG-I: tri-ing to discriminate between self and non-self RNA
49. Detection of Viral Infections by Innate Immunity
50. Removing the TREX1 Safety Net: Oxidized DNA Overcomes Immune Silencing by Exonuclease TREX1
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