1. Advancing HER2-low breast cancer management: enhancing diagnosis and treatment strategies
- Author
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Borstnar Simona, Bozovic-Spasojevic Ivana, Cvetanovic Ana, Plavetic Natalija Dedic, Konsoulova Assia, Matos Erika, Popovic Lazar, Popovska Savelina, Tomic Snjezana, and Vrdoljak Eduard
- Subjects
her2-low ,metastatic breast cancer ,balkans ,testing ,innovative treatment ,access ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Recent evidence brought by novel anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugates is leading to significant changes in HER2-negative breast cancer (BC) best practices. A new targetable category termed ‘HER2-low’ has been identified in tumors previously classified as ‘HER2-negative’. Daily practice in pathology and medical oncology is expected to align to current recommendations, but patient access to novel anticancer drugs across geographies might be impeded due to local challenges.
- Published
- 2024
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