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232 results on '"Brady, Samuel W."'

1. Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

Author

Islam, SM Ashiqul, Díaz-Gay, Marcos, Wu, Yang, Barnes, Mark, Vangara, Raviteja, Bergstrom, Erik N, He, Yudou, Vella, Mike, Wang, Jingwei, Teague, Jon W, Clapham, Peter, Moody, Sarah, Senkin, Sergey, Li, Yun Rose, Riva, Laura, Zhang, Tongwu, Gruber, Andreas J, Steele, Christopher D, Otlu, Burçak, Khandekar, Azhar, Abbasi, Ammal, Humphreys, Laura, Syulyukina, Natalia, Brady, Samuel W, Alexandrov, Boian S, Pillay, Nischalan, Zhang, Jinghui, Adams, David J, Martincorena, Iñigo, Wedge, David C, Landi, Maria Teresa, Brennan, Paul, Stratton, Michael R, Rozen, Steven G, and Alexandrov, Ludmil B

Subjects
Biological Sciences, Bioinformatics and Computational Biology, Genetics, Biotechnology, Tobacco Smoke and Health, Human Genome, Cancer, Prevention, Tobacco, Good Health and Well Being, cancer genomics, genomics, mutagenesis, mutational signatures
Abstract

Mutational signature analysis is commonly performed in cancer genomic studies. Here, we present SigProfilerExtractor, an automated tool for de novo extraction of mutational signatures, and benchmark it against another 13 bioinformatics tools by using 34 scenarios encompassing 2,500 simulated signatures found in 60,000 synthetic genomes and 20,000 synthetic exomes. For simulations with 5% noise, reflecting high-quality datasets, SigProfilerExtractor outperforms other approaches by elucidating between 20% and 50% more true-positive signatures while yielding 5-fold less false-positive signatures. Applying SigProfilerExtractor to 4,643 whole-genome- and 19,184 whole-exome-sequenced cancers reveals four novel signatures. Two of the signatures are confirmed in independent cohorts, and one of these signatures is associated with tobacco smoking. In summary, this report provides a reference tool for analysis of mutational signatures, a comprehensive benchmarking of bioinformatics tools for extracting signatures, and several novel mutational signatures, including one putatively attributed to direct tobacco smoking mutagenesis in bladder tissues.

Published
2022

4. The genomic landscape of pediatric acute lymphoblastic leukemia

Author

Brady, Samuel W., Roberts, Kathryn G., Gu, Zhaohui, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Dai, Yunfeng, Devidas, Meenakshi, Qu, Chunxu, Hill, Ashley N., Payne-Turner, Debbie, Ma, Xiaotu, Iacobucci, Ilaria, Baviskar, Pradyuamna, Wei, Lei, Arunachalam, Sasi, Hagiwara, Kohei, Liu, Yanling, Flasch, Diane A., Liu, Yu, Parker, Matthew, Chen, Xiaolong, Elsayed, Abdelrahman H., Pathak, Omkar, Li, Yongjin, Fan, Yiping, Michael, J. Robert, Rusch, Michael, Wilkinson, Mark R., Foy, Scott, Hedges, Dale J., Newman, Scott, Zhou, Xin, Wang, Jian, Reilly, Colleen, Sioson, Edgar, Rice, Stephen V., Pastor Loyola, Victor, Wu, Gang, Rampersaud, Evadnie, Reshmi, Shalini C., Gastier-Foster, Julie, Guidry Auvil, Jaime M., Gesuwan, Patee, Smith, Malcolm A., Winick, Naomi, Carroll, Andrew J., Heerema, Nyla A., Harvey, Richard C., Willman, Cheryl L., Larsen, Eric, Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Carroll, William L., Zweidler-McKay, Patrick A., Rabin, Karen R., Mattano, Leonard A., Maloney, Kelly W., Winter, Stuart S., Burke, Michael J., Salzer, Wanda, Dunsmore, Kimberly P., Angiolillo, Anne L., Crews, Kristine R., Downing, James R., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Yang, Jun J., Relling, Mary V., Gerhard, Daniela S., Loh, Mignon L., Hunger, Stephen P., Zhang, Jinghui, and Mullighan, Charles G.

Published
2022
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6. Chemotherapy and mismatch repair deficiency cooperate to fuel TP53 mutagenesis and ALL relapse

Author

Yang, Fan, Brady, Samuel W., Tang, Chao, Sun, Huiying, Du, Lijuan, Barz, Malwine J., Ma, Xiaotu, Chen, Yao, Fang, Houshun, Li, Xiaomeng, Kolekar, Pandurang, Pathak, Omkar, Cai, Jiaoyang, Ding, Lixia, Wang, Tianyi, von Stackelberg, Arend, Shen, Shuhong, Eckert, Cornelia, Klco, Jeffery M., Chen, Hongzhuan, Duan, Caiwen, Liu, Yu, Li, Hui, Li, Benshang, Kirschner-Schwabe, Renate, Zhang, Jinghui, and Zhou, Bin-Bing S.

Published
2021
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9. The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

Author

Pan, Min, Wright, William C., Chapple, Richard H., Zubair, Asif, Sandhu, Manbir, Batchelder, Jake E., Huddle, Brandt C., Low, Jonathan, Blankenship, Kaley B., Wang, Yingzhe, Gordon, Brittney, Archer, Payton, Brady, Samuel W., Natarajan, Sivaraman, Posgai, Matthew J., Schuetz, John, Miller, Darcie, Kalathur, Ravi, Chen, Siquan, Connelly, Jon Patrick, Babu, M. Madan, Dyer, Michael A., Pruett-Miller, Shondra M., Freeman, III, Burgess B., Chen, Taosheng, Godley, Lucy A., Blanchard, Scott C., Stewart, Elizabeth, Easton, John, and Geeleher, Paul

Published
2021
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10. The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms

Author

Schwartz, Jason R., Ma, Jing, Kamens, Jennifer, Westover, Tamara, Walsh, Michael P., Brady, Samuel W., Robert Michael, J., Chen, Xiaolong, Montefiori, Lindsey, Song, Guangchun, Wu, Gang, Wu, Huiyun, Branstetter, Cristyn, Hiltenbrand, Ryan, Walsh, Michael F., Nichols, Kim E., Maciaszek, Jamie L., Liu, Yanling, Kumar, Priyadarshini, Easton, John, Newman, Scott, Rubnitz, Jeffrey E., Mullighan, Charles G., Pounds, Stanley, Zhang, Jinghui, Gruber, Tanja, Ma, Xiaotu, and Klco, Jeffery M.

Published
2021
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11. Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

Author

Brady, Samuel W., Liu, Yanling, Ma, Xiaotu, Gout, Alexander M., Hagiwara, Kohei, Zhou, Xin, Wang, Jian, Macias, Michael, Chen, Xiaolong, Easton, John, Mulder, Heather L., Rusch, Michael, Wang, Lu, Nakitandwe, Joy, Lei, Shaohua, Davis, Eric M., Naranjo, Arlene, Cheng, Cheng, Maris, John M., Downing, James R., Cheung, Nai-Kong V., Hogarty, Michael D., Dyer, Michael A., and Zhang, Jinghui

Published
2020
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12. Table S6 from Clinical Significance of Novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease–Directed Therapy

Author

Jeha, Sima, primary, Choi, John, primary, Roberts, Kathryn G., primary, Pei, Deqing, primary, Coustan-Smith, Elaine, primary, Inaba, Hiroto, primary, Rubnitz, Jeffrey E., primary, Ribeiro, Raul C., primary, Gruber, Tanja A., primary, Raimondi, Susana C., primary, Karol, Seth E., primary, Qu, Chunxu, primary, Brady, Samuel W., primary, Gu, Zhaohui, primary, Yang, Jun J., primary, Cheng, Cheng, primary, Downing, James R., primary, Evans, Williams E., primary, Relling, Mary V., primary, Campana, Dario, primary, Mullighan, Charles G., primary, and Pui, Ching-Hon, primary

Published
2023
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13. Tables S1-S5 from Clinical Significance of Novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease–Directed Therapy

Author

Jeha, Sima, primary, Choi, John, primary, Roberts, Kathryn G., primary, Pei, Deqing, primary, Coustan-Smith, Elaine, primary, Inaba, Hiroto, primary, Rubnitz, Jeffrey E., primary, Ribeiro, Raul C., primary, Gruber, Tanja A., primary, Raimondi, Susana C., primary, Karol, Seth E., primary, Qu, Chunxu, primary, Brady, Samuel W., primary, Gu, Zhaohui, primary, Yang, Jun J., primary, Cheng, Cheng, primary, Downing, James R., primary, Evans, Williams E., primary, Relling, Mary V., primary, Campana, Dario, primary, Mullighan, Charles G., primary, and Pui, Ching-Hon, primary

Published
2023
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14. Data from Clinical Significance of Novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease–Directed Therapy

Author

Jeha, Sima, primary, Choi, John, primary, Roberts, Kathryn G., primary, Pei, Deqing, primary, Coustan-Smith, Elaine, primary, Inaba, Hiroto, primary, Rubnitz, Jeffrey E., primary, Ribeiro, Raul C., primary, Gruber, Tanja A., primary, Raimondi, Susana C., primary, Karol, Seth E., primary, Qu, Chunxu, primary, Brady, Samuel W., primary, Gu, Zhaohui, primary, Yang, Jun J., primary, Cheng, Cheng, primary, Downing, James R., primary, Evans, Williams E., primary, Relling, Mary V., primary, Campana, Dario, primary, Mullighan, Charles G., primary, and Pui, Ching-Hon, primary

Published
2023
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15. Supplementary Data-1 from Clinical Significance of Novel Subtypes of Acute Lymphoblastic Leukemia in the Context of Minimal Residual Disease–Directed Therapy

Author

Jeha, Sima, primary, Choi, John, primary, Roberts, Kathryn G., primary, Pei, Deqing, primary, Coustan-Smith, Elaine, primary, Inaba, Hiroto, primary, Rubnitz, Jeffrey E., primary, Ribeiro, Raul C., primary, Gruber, Tanja A., primary, Raimondi, Susana C., primary, Karol, Seth E., primary, Qu, Chunxu, primary, Brady, Samuel W., primary, Gu, Zhaohui, primary, Yang, Jun J., primary, Cheng, Cheng, primary, Downing, James R., primary, Evans, Williams E., primary, Relling, Mary V., primary, Campana, Dario, primary, Mullighan, Charles G., primary, and Pui, Ching-Hon, primary

Published
2023
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18. Data from Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing

Author

Newman, Scott, primary, Nakitandwe, Joy, primary, Kesserwan, Chimene A., primary, Azzato, Elizabeth M., primary, Wheeler, David A., primary, Rusch, Michael, primary, Shurtleff, Sheila, primary, Hedges, Dale J., primary, Hamilton, Kayla V., primary, Foy, Scott G., primary, Edmonson, Michael N., primary, Thrasher, Andrew, primary, Bahrami, Armita, primary, Orr, Brent A., primary, Klco, Jeffery M., primary, Gu, Jiali, primary, Harrison, Lynn W., primary, Wang, Lu, primary, Clay, Michael R., primary, Ouma, Annastasia, primary, Silkov, Antonina, primary, Liu, Yanling, primary, Zhang, Zhaojie, primary, Liu, Yu, primary, Brady, Samuel W., primary, Zhou, Xin, primary, Chang, Ti-Cheng, primary, Pande, Manjusha, primary, Davis, Eric, primary, Becksfort, Jared, primary, Patel, Aman, primary, Wilkinson, Mark R., primary, Rahbarinia, Delaram, primary, Kubal, Manish, primary, Maciaszek, Jamie L., primary, Pastor, Victor, primary, Knight, Jay, primary, Gout, Alexander M., primary, Wang, Jian, primary, Gu, Zhaohui, primary, Mullighan, Charles G., primary, McGee, Rose B., primary, Quinn, Emily A., primary, Nuccio, Regina, primary, Mostafavi, Roya, primary, Gerhardt, Elsie L., primary, Taylor, Leslie M., primary, Valdez, Jessica M., primary, Hines-Dowell, Stacy J., primary, Pappo, Alberto S., primary, Robinson, Giles, primary, Johnson, Liza-Marie, primary, Pui, Ching-Hon, primary, Ellison, David W., primary, Downing, James R., primary, Zhang, Jinghui, primary, and Nichols, Kim E., primary

Published
2023
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19. Supplementary Tables S1-S5 from The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment

Author

Brady, Samuel W., primary, Ma, Xiaotu, primary, Bahrami, Armita, primary, Satas, Gryte, primary, Wu, Gang, primary, Newman, Scott, primary, Rusch, Michael, primary, Putnam, Daniel K., primary, Mulder, Heather L., primary, Yergeau, Donald A., primary, Edmonson, Michael N., primary, Easton, John, primary, Alexandrov, Ludmil B., primary, Chen, Xiang, primary, Mardis, Elaine R., primary, Wilson, Richard K., primary, Downing, James R., primary, Pappo, Alberto S., primary, Raphael, Benjamin J., primary, Dyer, Michael A., primary, and Zhang, Jinghui, primary

Published
2023
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20. Supplementary Figure S2 from Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing

Author

Newman, Scott, primary, Nakitandwe, Joy, primary, Kesserwan, Chimene A., primary, Azzato, Elizabeth M., primary, Wheeler, David A., primary, Rusch, Michael, primary, Shurtleff, Sheila, primary, Hedges, Dale J., primary, Hamilton, Kayla V., primary, Foy, Scott G., primary, Edmonson, Michael N., primary, Thrasher, Andrew, primary, Bahrami, Armita, primary, Orr, Brent A., primary, Klco, Jeffery M., primary, Gu, Jiali, primary, Harrison, Lynn W., primary, Wang, Lu, primary, Clay, Michael R., primary, Ouma, Annastasia, primary, Silkov, Antonina, primary, Liu, Yanling, primary, Zhang, Zhaojie, primary, Liu, Yu, primary, Brady, Samuel W., primary, Zhou, Xin, primary, Chang, Ti-Cheng, primary, Pande, Manjusha, primary, Davis, Eric, primary, Becksfort, Jared, primary, Patel, Aman, primary, Wilkinson, Mark R., primary, Rahbarinia, Delaram, primary, Kubal, Manish, primary, Maciaszek, Jamie L., primary, Pastor, Victor, primary, Knight, Jay, primary, Gout, Alexander M., primary, Wang, Jian, primary, Gu, Zhaohui, primary, Mullighan, Charles G., primary, McGee, Rose B., primary, Quinn, Emily A., primary, Nuccio, Regina, primary, Mostafavi, Roya, primary, Gerhardt, Elsie L., primary, Taylor, Leslie M., primary, Valdez, Jessica M., primary, Hines-Dowell, Stacy J., primary, Pappo, Alberto S., primary, Robinson, Giles, primary, Johnson, Liza-Marie, primary, Pui, Ching-Hon, primary, Ellison, David W., primary, Downing, James R., primary, Zhang, Jinghui, primary, and Nichols, Kim E., primary

Published
2023
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21. Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem

Author

McLeod, Clay, primary, Gout, Alexander M., primary, Zhou, Xin, primary, Thrasher, Andrew, primary, Rahbarinia, Delaram, primary, Brady, Samuel W., primary, Macias, Michael, primary, Birch, Kirby, primary, Finkelstein, David, primary, Sunny, Jobin, primary, Mudunuri, Rahul, primary, Orr, Brent A., primary, Treadway, Madison, primary, Davidson, Bob, primary, Ard, Tracy K., primary, Chiao, Arthur, primary, Swistak, Andrew, primary, Wiggins, Stephanie, primary, Foy, Scott, primary, Wang, Jian, primary, Sioson, Edgar, primary, Wang, Shuoguo, primary, Michael, J. Robert, primary, Liu, Yu, primary, Ma, Xiaotu, primary, Patel, Aman, primary, Edmonson, Michael N., primary, Wilkinson, Mark R., primary, Frantz, Andrew M., primary, Chang, Ti-Cheng, primary, Tian, Liqing, primary, Lei, Shaohua, primary, Islam, S.M. Ashiqul, primary, Meyer, Christopher, primary, Thangaraj, Naina, primary, Tater, Pamella, primary, Kandali, Vijay, primary, Ma, Singer, primary, Nguyen, Tuan, primary, Serang, Omar, primary, McGuire, Irina, primary, Robison, Nedra, primary, Gentry, Darrell, primary, Tang, Xing, primary, Palmer, Lance E., primary, Wu, Gang, primary, Suh, Ed, primary, Tanner, Leigh, primary, McMurry, James, primary, Lear, Matthew, primary, Pappo, Alberto S., primary, Wang, Zhaoming, primary, Wilson, Carmen L., primary, Cheng, Yong, primary, Meshinchi, Soheil, primary, Alexandrov, Ludmil B., primary, Weiss, Mitchell J., primary, Armstrong, Gregory T., primary, Robison, Leslie L., primary, Yasui, Yutaka, primary, Nichols, Kim E., primary, Ellison, David W., primary, Bangur, Chaitanya, primary, Mullighan, Charles G., primary, Baker, Suzanne J., primary, Dyer, Michael A., primary, Miller, Geralyn, primary, Newman, Scott, primary, Rusch, Michael, primary, Daly, Richard, primary, Perry, Keith, primary, Downing, James R., primary, and Zhang, Jinghui, primary

Published
2023
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23. Supplementary Figures S1-S11 from The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment

Author

Brady, Samuel W., primary, Ma, Xiaotu, primary, Bahrami, Armita, primary, Satas, Gryte, primary, Wu, Gang, primary, Newman, Scott, primary, Rusch, Michael, primary, Putnam, Daniel K., primary, Mulder, Heather L., primary, Yergeau, Donald A., primary, Edmonson, Michael N., primary, Easton, John, primary, Alexandrov, Ludmil B., primary, Chen, Xiang, primary, Mardis, Elaine R., primary, Wilson, Richard K., primary, Downing, James R., primary, Pappo, Alberto S., primary, Raphael, Benjamin J., primary, Dyer, Michael A., primary, and Zhang, Jinghui, primary

Published
2023
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25. Data from The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment

Author

Brady, Samuel W., primary, Ma, Xiaotu, primary, Bahrami, Armita, primary, Satas, Gryte, primary, Wu, Gang, primary, Newman, Scott, primary, Rusch, Michael, primary, Putnam, Daniel K., primary, Mulder, Heather L., primary, Yergeau, Donald A., primary, Edmonson, Michael N., primary, Easton, John, primary, Alexandrov, Ludmil B., primary, Chen, Xiang, primary, Mardis, Elaine R., primary, Wilson, Richard K., primary, Downing, James R., primary, Pappo, Alberto S., primary, Raphael, Benjamin J., primary, Dyer, Michael A., primary, and Zhang, Jinghui, primary

Published
2023
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26. Supplementary Tables from Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing

Author

Newman, Scott, primary, Nakitandwe, Joy, primary, Kesserwan, Chimene A., primary, Azzato, Elizabeth M., primary, Wheeler, David A., primary, Rusch, Michael, primary, Shurtleff, Sheila, primary, Hedges, Dale J., primary, Hamilton, Kayla V., primary, Foy, Scott G., primary, Edmonson, Michael N., primary, Thrasher, Andrew, primary, Bahrami, Armita, primary, Orr, Brent A., primary, Klco, Jeffery M., primary, Gu, Jiali, primary, Harrison, Lynn W., primary, Wang, Lu, primary, Clay, Michael R., primary, Ouma, Annastasia, primary, Silkov, Antonina, primary, Liu, Yanling, primary, Zhang, Zhaojie, primary, Liu, Yu, primary, Brady, Samuel W., primary, Zhou, Xin, primary, Chang, Ti-Cheng, primary, Pande, Manjusha, primary, Davis, Eric, primary, Becksfort, Jared, primary, Patel, Aman, primary, Wilkinson, Mark R., primary, Rahbarinia, Delaram, primary, Kubal, Manish, primary, Maciaszek, Jamie L., primary, Pastor, Victor, primary, Knight, Jay, primary, Gout, Alexander M., primary, Wang, Jian, primary, Gu, Zhaohui, primary, Mullighan, Charles G., primary, McGee, Rose B., primary, Quinn, Emily A., primary, Nuccio, Regina, primary, Mostafavi, Roya, primary, Gerhardt, Elsie L., primary, Taylor, Leslie M., primary, Valdez, Jessica M., primary, Hines-Dowell, Stacy J., primary, Pappo, Alberto S., primary, Robinson, Giles, primary, Johnson, Liza-Marie, primary, Pui, Ching-Hon, primary, Ellison, David W., primary, Downing, James R., primary, Zhang, Jinghui, primary, and Nichols, Kim E., primary

Published
2023
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27. Supplementary Tables from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem

Author

McLeod, Clay, primary, Gout, Alexander M., primary, Zhou, Xin, primary, Thrasher, Andrew, primary, Rahbarinia, Delaram, primary, Brady, Samuel W., primary, Macias, Michael, primary, Birch, Kirby, primary, Finkelstein, David, primary, Sunny, Jobin, primary, Mudunuri, Rahul, primary, Orr, Brent A., primary, Treadway, Madison, primary, Davidson, Bob, primary, Ard, Tracy K., primary, Chiao, Arthur, primary, Swistak, Andrew, primary, Wiggins, Stephanie, primary, Foy, Scott, primary, Wang, Jian, primary, Sioson, Edgar, primary, Wang, Shuoguo, primary, Michael, J. Robert, primary, Liu, Yu, primary, Ma, Xiaotu, primary, Patel, Aman, primary, Edmonson, Michael N., primary, Wilkinson, Mark R., primary, Frantz, Andrew M., primary, Chang, Ti-Cheng, primary, Tian, Liqing, primary, Lei, Shaohua, primary, Islam, S.M. Ashiqul, primary, Meyer, Christopher, primary, Thangaraj, Naina, primary, Tater, Pamella, primary, Kandali, Vijay, primary, Ma, Singer, primary, Nguyen, Tuan, primary, Serang, Omar, primary, McGuire, Irina, primary, Robison, Nedra, primary, Gentry, Darrell, primary, Tang, Xing, primary, Palmer, Lance E., primary, Wu, Gang, primary, Suh, Ed, primary, Tanner, Leigh, primary, McMurry, James, primary, Lear, Matthew, primary, Pappo, Alberto S., primary, Wang, Zhaoming, primary, Wilson, Carmen L., primary, Cheng, Yong, primary, Meshinchi, Soheil, primary, Alexandrov, Ludmil B., primary, Weiss, Mitchell J., primary, Armstrong, Gregory T., primary, Robison, Leslie L., primary, Yasui, Yutaka, primary, Nichols, Kim E., primary, Ellison, David W., primary, Bangur, Chaitanya, primary, Mullighan, Charles G., primary, Baker, Suzanne J., primary, Dyer, Michael A., primary, Miller, Geralyn, primary, Newman, Scott, primary, Rusch, Michael, primary, Daly, Richard, primary, Perry, Keith, primary, Downing, James R., primary, and Zhang, Jinghui, primary

Published
2023
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28. Supplementary Data from St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem

Author

McLeod, Clay, primary, Gout, Alexander M., primary, Zhou, Xin, primary, Thrasher, Andrew, primary, Rahbarinia, Delaram, primary, Brady, Samuel W., primary, Macias, Michael, primary, Birch, Kirby, primary, Finkelstein, David, primary, Sunny, Jobin, primary, Mudunuri, Rahul, primary, Orr, Brent A., primary, Treadway, Madison, primary, Davidson, Bob, primary, Ard, Tracy K., primary, Chiao, Arthur, primary, Swistak, Andrew, primary, Wiggins, Stephanie, primary, Foy, Scott, primary, Wang, Jian, primary, Sioson, Edgar, primary, Wang, Shuoguo, primary, Michael, J. Robert, primary, Liu, Yu, primary, Ma, Xiaotu, primary, Patel, Aman, primary, Edmonson, Michael N., primary, Wilkinson, Mark R., primary, Frantz, Andrew M., primary, Chang, Ti-Cheng, primary, Tian, Liqing, primary, Lei, Shaohua, primary, Islam, S.M. Ashiqul, primary, Meyer, Christopher, primary, Thangaraj, Naina, primary, Tater, Pamella, primary, Kandali, Vijay, primary, Ma, Singer, primary, Nguyen, Tuan, primary, Serang, Omar, primary, McGuire, Irina, primary, Robison, Nedra, primary, Gentry, Darrell, primary, Tang, Xing, primary, Palmer, Lance E., primary, Wu, Gang, primary, Suh, Ed, primary, Tanner, Leigh, primary, McMurry, James, primary, Lear, Matthew, primary, Pappo, Alberto S., primary, Wang, Zhaoming, primary, Wilson, Carmen L., primary, Cheng, Yong, primary, Meshinchi, Soheil, primary, Alexandrov, Ludmil B., primary, Weiss, Mitchell J., primary, Armstrong, Gregory T., primary, Robison, Leslie L., primary, Yasui, Yutaka, primary, Nichols, Kim E., primary, Ellison, David W., primary, Bangur, Chaitanya, primary, Mullighan, Charles G., primary, Baker, Suzanne J., primary, Dyer, Michael A., primary, Miller, Geralyn, primary, Newman, Scott, primary, Rusch, Michael, primary, Daly, Richard, primary, Perry, Keith, primary, Downing, James R., primary, and Zhang, Jinghui, primary

Published
2023
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29. Data from The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State

Author

Yoo, Jae Hyuk, primary, Brady, Samuel W., primary, Acosta-Alvarez, Lehi, primary, Rogers, Aaron, primary, Peng, Jingfu, primary, Sorensen, Lise K., primary, Wolff, Roger K., primary, Mleynek, Tara, primary, Shin, Donghan, primary, Rich, Coulson P., primary, Kircher, David A., primary, Bild, Andrea, primary, Odelberg, Shannon J., primary, Li, Dean Y., primary, Holmen, Sheri L., primary, and Grossmann, Allie H., primary

Published
2023
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30. Figure S2 from The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State

Author

Yoo, Jae Hyuk, primary, Brady, Samuel W., primary, Acosta-Alvarez, Lehi, primary, Rogers, Aaron, primary, Peng, Jingfu, primary, Sorensen, Lise K., primary, Wolff, Roger K., primary, Mleynek, Tara, primary, Shin, Donghan, primary, Rich, Coulson P., primary, Kircher, David A., primary, Bild, Andrea, primary, Odelberg, Shannon J., primary, Li, Dean Y., primary, Holmen, Sheri L., primary, and Grossmann, Allie H., primary

Published
2023
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31. Supplementary Figure S5 from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer

Author

Jain, Shalini, primary, Wang, Xiao, primary, Chang, Chia-Chi, primary, Ibarra-Drendall, Catherine, primary, Wang, Hai, primary, Zhang, Qingling, primary, Brady, Samuel W., primary, Li, Ping, primary, Zhao, Hong, primary, Dobbs, Jessica, primary, Kyrish, Matt, primary, Tkaczyk, Tomasz S., primary, Ambrose, Adrian, primary, Sistrunk, Christopher, primary, Arun, Banu K., primary, Richards-Kortum, Rebecca, primary, Jia, Wei, primary, Seewaldt, Victoria L., primary, and Yu, Dihua, primary

Published
2023
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32. Data from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer

Author

Jain, Shalini, primary, Wang, Xiao, primary, Chang, Chia-Chi, primary, Ibarra-Drendall, Catherine, primary, Wang, Hai, primary, Zhang, Qingling, primary, Brady, Samuel W., primary, Li, Ping, primary, Zhao, Hong, primary, Dobbs, Jessica, primary, Kyrish, Matt, primary, Tkaczyk, Tomasz S., primary, Ambrose, Adrian, primary, Sistrunk, Christopher, primary, Arun, Banu K., primary, Richards-Kortum, Rebecca, primary, Jia, Wei, primary, Seewaldt, Victoria L., primary, and Yu, Dihua, primary

Published
2023
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33. Supplementary Table and Figure Legends from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer

Author

Jain, Shalini, primary, Wang, Xiao, primary, Chang, Chia-Chi, primary, Ibarra-Drendall, Catherine, primary, Wang, Hai, primary, Zhang, Qingling, primary, Brady, Samuel W., primary, Li, Ping, primary, Zhao, Hong, primary, Dobbs, Jessica, primary, Kyrish, Matt, primary, Tkaczyk, Tomasz S., primary, Ambrose, Adrian, primary, Sistrunk, Christopher, primary, Arun, Banu K., primary, Richards-Kortum, Rebecca, primary, Jia, Wei, primary, Seewaldt, Victoria L., primary, and Yu, Dihua, primary

Published
2023
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34. Table S1 from The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State

Author

Yoo, Jae Hyuk, primary, Brady, Samuel W., primary, Acosta-Alvarez, Lehi, primary, Rogers, Aaron, primary, Peng, Jingfu, primary, Sorensen, Lise K., primary, Wolff, Roger K., primary, Mleynek, Tara, primary, Shin, Donghan, primary, Rich, Coulson P., primary, Kircher, David A., primary, Bild, Andrea, primary, Odelberg, Shannon J., primary, Li, Dean Y., primary, Holmen, Sheri L., primary, and Grossmann, Allie H., primary

Published
2023
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35. Supplementary Methods and References from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer

Author

Jain, Shalini, primary, Wang, Xiao, primary, Chang, Chia-Chi, primary, Ibarra-Drendall, Catherine, primary, Wang, Hai, primary, Zhang, Qingling, primary, Brady, Samuel W., primary, Li, Ping, primary, Zhao, Hong, primary, Dobbs, Jessica, primary, Kyrish, Matt, primary, Tkaczyk, Tomasz S., primary, Ambrose, Adrian, primary, Sistrunk, Christopher, primary, Arun, Banu K., primary, Richards-Kortum, Rebecca, primary, Jia, Wei, primary, Seewaldt, Victoria L., primary, and Yu, Dihua, primary

Published
2023
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36. Supplementary Table S1 from Src Inhibition Blocks c-Myc Translation and Glucose Metabolism to Prevent the Development of Breast Cancer

Author

Jain, Shalini, primary, Wang, Xiao, primary, Chang, Chia-Chi, primary, Ibarra-Drendall, Catherine, primary, Wang, Hai, primary, Zhang, Qingling, primary, Brady, Samuel W., primary, Li, Ping, primary, Zhao, Hong, primary, Dobbs, Jessica, primary, Kyrish, Matt, primary, Tkaczyk, Tomasz S., primary, Ambrose, Adrian, primary, Sistrunk, Christopher, primary, Arun, Banu K., primary, Richards-Kortum, Rebecca, primary, Jia, Wei, primary, Seewaldt, Victoria L., primary, and Yu, Dihua, primary

Published
2023
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37. Supplementary Figure 2 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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38. Supplementary Figure 7 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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39. Supplementary Figure 3 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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40. Supplementary Figure 4 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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41. Supplementary Figure 9 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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42. Supplementary Figure 1 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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43. Supplementary Figure 8 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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44. Supplementary Table 1 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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45. Supplementary Figure Legends 1-9 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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46. Supplementary Figure 5 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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47. Supplementary Figure 6 from Concomitant Targeting of Tumor Cells and Induction of T-cell Response Synergizes to Effectively Inhibit Trastuzumab-Resistant Breast Cancer

Author

Wang, Qingfei, primary, Li, Shau-Hsuan, primary, Wang, Hai, primary, Xiao, Yi, primary, Sahin, Ozgur, primary, Brady, Samuel W., primary, Li, Ping, primary, Ge, Hailiang, primary, Jaffee, Elizabeth M., primary, Muller, William J., primary, Hortobagyi, Gabriel N., primary, and Yu, Dihua, primary

Published
2023
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49. Additional file 1 of Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor

Author

Arunachalam, Sasi, Szlachta, Karol, Brady, Samuel W., Ma, Xiaotu, Ju, Bensheng, Shaner, Bridget, Mulder, Heather L., Easton, John, Raphael, Benjamin J., Myers, Matthew, Tinkle, Christopher, Allen, Sariah J., Orr, Brent A., Wetmore, Cynthia J., Baker, Suzanne J., and Zhang, Jinghui

Abstract

Additional file1. Supplementary methods.

Published
2022
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50. Additional file 2 of Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor

Author

Arunachalam, Sasi, Szlachta, Karol, Brady, Samuel W., Ma, Xiaotu, Ju, Bensheng, Shaner, Bridget, Mulder, Heather L., Easton, John, Raphael, Benjamin J., Myers, Matthew, Tinkle, Christopher, Allen, Sariah J., Orr, Brent A., Wetmore, Cynthia J., Baker, Suzanne J., and Zhang, Jinghui

Abstract

Additional file2. Supplementary figures.

Published
2022
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