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1. Unprescribed cannabinoids and multiple sclerosis: a multicenter, cross-sectional, epidemiological study in Lombardy, Italy

Author

Giossi, Riccardo, Mercenari, Martina, Filippi, Massimo, Zanetta, Chiara, Antozzi, Carlo Giuseppe, Brambilla, Laura, Confalonieri, Paolo, Crisafulli, Sebastiano Giuseppe, Tomas Roldan, Eugenia, Annovazzi, Pietro, Conti, Marta Zaffira, Barrilà, Caterina, Ronzoni, Marco, Grobberio, Monica, Negri, Attilio, Gustavsen, Stefan, and Torri Clerici, Valentina

Published
2024
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3. Correction to: Unprescribed cannabinoids and multiple sclerosis: a multicenter, cross-sectional, epidemiological study in Lombardy, Italy

Author

Giossi, Riccardo, Mercenari, Martina, Filippi, Massimo, Zanetta, Chiara, Antozzi, Carlo Giuseppe, Brambilla, Laura, Confalonieri, Paolo, Crisafulli, Sebastiano Giuseppe, Tomas Roldan, Eugenia, Annovazzi, Pietro, Conti, Marta Zaffira, Barrilà, Caterina, Ronzoni, Marco, Grobberio, Monica, Negri, Attilio, Gustavsen, Stefan, and Torri Clerici, Valentina

Published
2024
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4. Signs and symptoms of COVID‐19 in patients with multiple sclerosis

Author

Schiavetti, Irene, Carmisciano, Luca, Ponzano, Marta, Cordioli, Cinzia, Cocco, Eleonora, Marfia, Girolama Alessandra, Inglese, Matilde, Filippi, Massimo, Radaelli, Marta, Bergamaschi, Roberto, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Confalonieri, Paolo, Perini, Paola, Trojano, Maria, Lanzillo, Roberta, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria Pia, Group, MuSC‐19 Study, Abbadessa, Gianmarco, Aguglia, Umberto, Allegorico, Lia, Allegri, Beatrice Maria Rossi, Alteno, Anastasia, Amato, Maria Pia, Annovazzi, Pietro, Antozzi, Carlo, Appendino, Lucia, Arena, Sebastiano, Baione, Viola, Balgera, Roberto, Barcella, Valeria, Baroncini, Damiano, Barrilà, Caterina, Bellacosa, Alessandra, Bellucci, Gianmarco, Bergamaschi, Valeria, Bezzini, Daiana, Biolzi, Beatrice, Bisecco, Alvino, Bonavita, Simona, Borriello, Giovanna, Bosa, Chiara, Bosco, Antonio, Bovis, Francesca, Bozzali, Marco, Brambilla, Laura, Morra, Vincenzo Brescia, Buccafusca, Maria, Bucciantini, Elisabetta, Bucello, Sebastiano, Buscarinu, Maria Chiara, Cabboi, Maria Paola, Calabrese, Massimiliano, Calabria, Francesca, Caleri, Francesca, Camilli, Federico, Caniatti, Luisa Maria, Cantello, Roberto, Capra, Ruggero, Capuano, Rocco, Carta, Patrizia, Celani, Maria Grazia, Cellerino, Maria, Cerqua, Raffaella, Chisari, Clara, Clerici, Raffaella, Clerico, Marinella, Cola, Gaia, Conte, Antonella, Conti, Marta Zaffira, Cordano, Christian, Cordera, Susanna, Corea, Francesco, Correale, Claudio, Cottone, Salvatore, Crescenzo, Francesco, Curti, Erica, d’Ambrosio, Alessandro, D’Amico, Emanuele, Danni, Maura Chiara, d’Arma, Alessia, Dattola, Vincenzo, de Biase, Stefano, De Luca, Giovanna, De Mercanti, Stefania Federica, De Mitri, Paolo, De Stefano, Nicola, Della Cava, Fabio Maria, Della Cava, Marco, and Di Lemme, Sonia

Subjects
Neurosciences, Multiple Sclerosis, Brain Disorders, Pain Research, Neurodegenerative, Good Health and Well Being, Humans, Aged, COVID-19, Ageusia, SARS-CoV-2, Anosmia, MuSC-19 Study Group, demyelinating diseases, disease-modifying treatment, multiple sclerosis, neurological disorders, Clinical Sciences, Neurology & Neurosurgery
Abstract

Background and purposeClinical outcomes of multiple sclerosis (MS) patients affected by coronavirus disease 2019 (COVID-19) have been thoroughly investigated, but a further analysis on main signs and symptoms and their risk factors still needs attention. The objective of this study was to group together and describe based on similarity the most common signs and symptoms of COVID-19 in MS patients and identify all factors associated with their manifestation.MethodLogistic and linear regression models were run to recognize factors associated with each pooled group of symptoms and their total number.ResultsFrom March 2020 to November 2021, data were collected from 1354 MS patients with confirmed infection of COVID-19. Ageusia and anosmia was less frequent in older people (odds ratio [OR] 0.98; p = 0.005) and more in smoker patients (OR 1.39; p = 0.049). Smoke was also associated with an incremental number of symptoms (OR 1.24; p = 0.031), substance abuse (drugs or alcohol), conjunctivitis and rash (OR 5.20; p = 0.042) and the presence of at least one comorbidity with shortness of breath, tachycardia or chest pain (OR 1.24; p = 0.008). Some disease-modifying therapies were associated with greater frequencies of certain COVID-19 symptoms (association between anti-CD20 therapies and increment in the number of concomitant symptoms: OR 1.29; p = 0.05). Differences in frequencies between the three waves were found for flu-like symptoms (G1, p = 0.024), joint or muscle pain (G2, p = 0.013) and ageusia and anosmia (G5, p

Published
2022

7. The effect of air pollution on COVID‐19 severity in a sample of patients with multiple sclerosis

Author

Bergamaschi, Roberto, Ponzano, Marta, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Morra, Vincenzo Brescia, Pisoni, Enrico, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Sormani, Maria Pia, Abbadessa, Gianmarco, Aguglia, Umberto, Allegorico, Lia, Allegri, Rossi Beatrice Maria, Alteno, Anastasia, Amato, Maria Pia, Annovazzi, Pietro, Antozzi, Carlo, Appendino, Lucia, Arena, Sebastiano, Baione, Viola, Balgera, Roberto, Barcella, Valeria, Baroncini, Damiano, Barrilà, Caterina, Battaglia, Mario A, Bellacosa, Alessandra, Bellucci, Gianmarco, Bergamaschi, Valeria, Bezzini, Daiana, Biolzi, Beatrice, Bisecco, Alvino, Bonavita, Simona, Borriello, Giovanna, Bosa, Chiara, Bosco, Antonio, Bovis, Francesca, Bozzali, Marco, Brambilla, Laura, Brescia, Morra Vincenzo, Buccafusca, Maria, Bucciantini, Elisabetta, Bucello, Sebastiano, Buscarinu, Maria Chiara, Cabboi, Maria Paola, Calabrese, Massimiliano, Calabria, Francesca, Caleri, Francesca, Camilli, Federico, Caniatti, Luisa Maria, Cantello, Roberto, Capra, Ruggero, Capuano, Rocco, Carta, Patrizia, Celani, Maria Grazia, Cellerino, Maria, Cerqua, Raffaella, Chisari, Clara, Clerici, Raffaella, Clerico, Marinella, Cola, Gaia, Conte, Antonella, Conti, Marta Zaffira, Cordano, Christian, Cordera, Susanna, Corea, Francesco, Correale, Claudio, Cottone, Salvatore, Crescenzo, Francesco, Curti, Erica, d'Ambrosio, Alessandro, and D'Amico, Emanuele

Subjects
Clinical Research, Neurosciences, Multiple Sclerosis, Brain Disorders, Autoimmune Disease, Neurodegenerative, Climate-Related Exposures and Conditions, Good Health and Well Being, Sustainable Cities and Communities, Air Pollution, COVID-19, Humans, Particulate Matter, SARS-CoV-2, MuSC-19 study group, air pollution, coronavirus, multiple sclerosis, Clinical Sciences, Neurology & Neurosurgery
Abstract

Background and purposeSome studies have shown that air pollution, often assessed by thin particulate matter with diameter below 2.5 µg/m3 (PM2.5), may contribute to severe COVID-19 courses, as well as play a role in the onset and evolution of multiple sclerosis (MS). However, the impact of air pollution on COVID-19 has never been explored specifically amongst patients with MS (PwMS). This retrospective observational study aims to explore associations between PM2.5 and COVID-19 severity amongst PwMS.MethodsData were retrieved from an Italian web-based platform (MuSC-19) which includes PwMS with COVID-19. PM2.5 2016-2018 average concentrations were provided by the Copernicus Atmospheric Monitoring Service. Italian patients inserted in the platform from 15 January 2020 to 9 April 2021 with a COVID-19 positive test were included. Ordered logistic regression models were used to study associations between PM2.5 and COVID-19 severity.ResultsIn all, 1087 patients, of whom 13% required hospitalization and 2% were admitted to an intensive care unit or died, were included. Based on the multivariate analysis, higher concentrations of PM2.5 increased the risk of worse COVID-19 course (odds ratio 1.90; p = 0.009).ConclusionsEven if several other factors explain the unfavourable course of COVID-19 in PwMS, the role of air pollutants must be considered and further investigated.

Published
2022

8. Disease‐Modifying Therapies and Coronavirus Disease 2019 Severity in Multiple Sclerosis

Author

Sormani, Maria P, De Rossi, Nicola, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Moiola, Lucia, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, Trojano, Maria, Zaratin, Paola, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario A, Patti, Francesco, Salvetti, Marco, Nozzolillo, Agostino, Bellacosa, Alessandra, Protti, Alessandra, Di Sapio, Alessia, Signori, Alessio, Petrone, Alfredo, Bisecco, Alvino, Iovino, Aniello, Dutto, Anna, Repice, Anna Maria, Conte, Antonella, Bertolotto, Antonio, Bosco, Antonio, Gallo, Antonio, Zito, Antonio, Sartori, Arianna, Giometto, Bruno, Tortorella, Carla, Antozzi, Carlo, Pozzilli, Carlo, Mancinelli, Chiara Rosa, Zanetta, Chiara, Cordano, Christian, Scandellari, Cinzia, Guaschino, Clara, Gasperini, Claudio, Solaro, Claudio, Fioretti, Cristina, Bezzini, Daiana, Marastoni, Damiano, Paolicelli, Damiano, Vecchio, Domizia, Landi, Doriana, Bucciantini, Elisabetta, Pedrazzoli, Elisabetta, Signoriello, Elisabetta, Sbragia, Elvira, Susani, Emanuela Laura, Curti, Erica, Milano, Eva, Marinelli, Fabiana, Camilli, Federico, Boneschi, Filippo Martinelli, Govone, Flora, Bovis, Francesca, Calabria, Francesca, Caleri, Francesca, Rinaldi, Francesca, Vitetta, Francesca, Corea, Francesco, Crescenzo, Francesco, Teatini, Francesco, Tabiadon, Giulietta, Granella, Franco, Boffa, Giacomo, Lus, Giacomo, Brichetto, Giampaolo, Maniscalco, Giorgia Teresa, Borriello, Giovanna, De Luca, Giovanna, Konrad, Giovanna, Vaula, Giovanna, Marfia, Girolama Alessandra, Mallucci, Giulia, Liberatore, Giuseppe, Salemi, Giuseppe, Miele, Giuseppina, Sibilia, Grazia, Pesci, Ilaria, Brambilla, Laura, Lopiano, Leonardo, Sinisi, Leonardo, Pasquali, Livia, Saraceno, Lorenzo, Chiveri, Luca, Mancinelli, Luca, and Grimaldi, Luigi ME

Subjects
Pneumonia & Influenza, Neurodegenerative, Clinical Research, Autoimmune Disease, Brain Disorders, Lung, Multiple Sclerosis, Pneumonia, Neurosciences, Neurological, Good Health and Well Being, Adolescent, Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, Humanized, COVID-19, Dimethyl Fumarate, Female, Fingolimod Hydrochloride, Hospitalization, Humans, Immunologic Factors, Immunosuppressive Agents, Intensive Care Units, Interferons, Male, Middle Aged, Mortality, Natalizumab, SARS-CoV-2, Severity of Illness Index, Young Adult, Musc-19 Study Group, Clinical Sciences, Neurology & Neurosurgery
Abstract

ObjectiveThis study was undertaken to assess the impact of immunosuppressive and immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID-19) in people with multiple sclerosis (PwMS).MethodsWe retrospectively collected data of PwMS with suspected or confirmed COVID-19. All the patients had complete follow-up to death or recovery. Severe COVID-19 was defined by a 3-level variable: mild disease not requiring hospitalization versus pneumonia or hospitalization versus intensive care unit (ICU) admission or death. We evaluated baseline characteristics and MS therapies associated with severe COVID-19 by multivariate and propensity score (PS)-weighted ordinal logistic models. Sensitivity analyses were run to confirm the results.ResultsOf 844 PwMS with suspected (n = 565) or confirmed (n = 279) COVID-19, 13 (1.54%) died; 11 of them were in a progressive MS phase, and 8 were without any therapy. Thirty-eight (4.5%) were admitted to an ICU; 99 (11.7%) had radiologically documented pneumonia; 96 (11.4%) were hospitalized. After adjusting for region, age, sex, progressive MS course, Expanded Disability Status Scale, disease duration, body mass index, comorbidities, and recent methylprednisolone use, therapy with an anti-CD20 agent (ocrelizumab or rituximab) was significantly associated (odds ratio [OR] = 2.37, 95% confidence interval [CI] = 1.18-4.74, p = 0.015) with increased risk of severe COVID-19. Recent use (

Published
2021

12. Clinical relevance of thymic and bone marrow outputs in multiple sclerosis patients treated with alemtuzumab

Author

Sottini, Alessandra, Quaresima, Virginia, Barbaro, Mosè, Moiola, Lucia, Filippi, Massimo, Malentacchi, Maria, Capobianco, Marco, Puthenparampil, Marco, Gallo, Paolo, Cocco, Eleonora, Frau, Jessica, Zaffaroni, Mauro, Guaschino, Clara, Stampatori, Chiara, Mancinelli, Chiara, Brambilla, Laura, Clerici, Valentina Torri, Vianello, Marika, Vitetta, Francesca, Ferraro, Diana, Rosettani, Pamela, Danni, Maura Chiara, Conti, Marta, Grimoldi, Maria, Capra, Ruggero, and Imberti, Luisa

Published
2023
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15. Non Clinical Model to Assess the Mechanism of Action of a Combined Hyaluronic Acid, Chondroitin Sulfate and Calcium Chloride: HA+CS+CaCl2 Solution on a 3D Human Reconstructed Bladder Epithelium

Author

Brambilla,Laura, Frangione,Valeria, Meloni,Marisa, Brambilla,Laura, Frangione,Valeria, and Meloni,Marisa

Abstract

Laura Brambilla,1 Valeria Frangione,2 Marisa Meloni1 1VitroScreen, in vitro Research Laboratory, Milan, Italy; 2IBSA Institut Biochimique SA, Pambio-Noranco, SwitzerlandCorrespondence: Marisa Meloni, VitroScreen, Via Mosè Bianchi, 103, Milan, 20149, Italy, Tel +39 02 89077608, Email marisa.meloni@vitroscreen.comPurpose: Medical Device Regulation (EU) 2017/745 requires the principal mode of action (MoA) to be demonstrated by experimental data. The MoA of Ialuril® Prefill (combined as HA+CS+CaCl2: sodium hyaluronate 1.6%, sodium chondroitin sulphate 2% w/v and calcium chloride 0.87%) Class III medical device, indicated for intravesical instillation to reduce urinary tract infections, has been evaluated on a 3D reconstructed human bladder epithelium (HBE).Methods: Three experimental designs; i) E. coli strain selection (DSM 103538, DSM 1103) to investigate the HA+CS+CaCl2 properties in modifying bacterial growth in liquid broth (CFU 4h and 24h) at 80%, 50% and 25% concentrations; ii) evaluation of film forming properties on HBE after 15 min exposure by quantifying caffeine permeation across the epithelium; iii) capacity to counteract E. coli adhesion and biofilm formation on colonized HBE by viable counts and ultrastructural analysis by scanning electron microscopy (SEM) using ciprofloxacin as the reference antimicrobial molecule.Results: No significant differences were observed in bacterial viability for both the E. coli strains. HA+CS+CaCl2 reduced caffeine permeation of 51.7% and 38.1% at 1h and 2h, respectively and determined a significant decrease in caffeine permeation rate at both timepoints supporting HA+CS+CaCl2 capacity to firmly adhere to the bladder epithelium creating a physical barrier on the surface. The viable counts in HBE treated tissues then infected with E. coli resulted not different from the negative control suggesting that the device did not inhibit E. coli growth. SEM images showed homogenous product distribution over the HBE surface and confi

Published
2024

17. Risk of Getting COVID-19 in People With Multiple Sclerosis: A Case-Control Study

Author

Iaffaldano, Pietro, Lucisano, Giuseppe, Manni, Alessia, Paolicelli, Damiano, Patti, Francesco, Capobianco, Marco, Brescia Morra, Vincenzo, Sola, Patrizia, Pesci, Ilaria, Lus, Giacomo, De Luca, Giovanna, Lugaresi, Alessandra, Cavalla, Paola, Montepietra, Sara, Maniscalco, Giorgia Teresa, Granella, Franco, Ragonese, Paolo, Vianello, Marika, Brambilla, Laura, Totaro, Rocco, Toscano, Simona, Malucchi, Simona, Petracca, Maria, Moiola, Lucia, Ferraro, Diana, Lepore, Vito, Mosconi, Paola, Ponzio, Michela, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Filippi, Massimo, Amato, Maria Pia, and Trojano, Maria

Published
2022
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18. Efficacy of different rituximab therapeutic strategies in patients with neuromyelitis optica spectrum disorders

Author

Novi, Giovanni, Bovis, Francesca, Capobianco, Marco, Frau, Jessica, Mataluni, Giorgia, Curti, Erica, Zuliani, Luigi, Cavalla, Paola, Brambilla, Laura, Annovazzi, Pietro, Repice, Anna Maria, Lanzillo, Roberta, Esposito, Sabrina, Benedetti, Luana, Maietta, Ilaria, Sica, Francesco, Buttari, Fabio, Malucchi, Simona, Fenu, Giuseppe, Landi, Doriana, Bosa, Chiara, Realmuto, Sabrina, Malentacchi, Maria, Granella, Franco, Signori, Alessio, Bonavita, Simona, Uccelli, Antonio, and Sormani, Maria Pia

Published
2019
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19. COVID-19 Severity in Multiple Sclerosis: Putting Data Into Context

Author

Sormani, Maria Pia, Schiavetti, Irene, Carmisciano, Luca, Cordioli, Cinzia, Filippi, Massimo, Radaelli, Marta, Immovilli, Paolo, Capobianco, Marco, De Rossi, Nicola, Brichetto, Giampaolo, Cocco, Eleonora, Scandellari, Cinzia, Cavalla, Paola, Pesci, Ilaria, Zito, Antonio, Confalonieri, Paolo, Marfia, Girolama Alessandra, Perini, Paola, Inglese, Matilde, Trojano, Maria, Brescia Morra, Vincenzo, Tedeschi, Gioacchino, Comi, Giancarlo, Battaglia, Mario Alberto, Patti, Francesco, Salvetti, Marco, Abbadessa, Gianmarco, Aguglia, Umberto, Allegorico, Lia, Allegri Rossi, Beatrice Maria, Amato, Maria Pia, Annovazzi, Pietro, Antozzi, Carlo, Appendino, Lucia, Arena, Sebastiano, Baione, Viola, Balgera, Roberto, Barcella, Valeria, Baroncini, Damiano, Barrilà, Caterina, Bellacosa, Alessandra, Bellucci, Gianmarco, Bergamaschi, Roberto, Bergamaschi, Valeria, Bezzini, Daiana, Biolzi, Beatrice, Bisecco, Alvino, Bonavita, Simona, Borriello, Giovanna, Bosa, Chiara, Bosco, Antonio, Bovis, Francesca, Bozzali, Marco, Brambilla, Laura, Buccafusca, Maria, Bucciantini, Elisabetta, Bucello, Sebastiano, Buscarinu, Maria Chiara, Cabboi, Maria Paola, Calabrese, Massimiliano, Calabria, Francesca, Caleri, Francesca, Camilli, Federico, Caniatti, Luisa Maria, Cantello, Roberto, Capra, Ruggero, Capuano, Rocco, Carta, Patrizia, Celani, Maria Grazia, Cellerino, Maria, Cerqua, Raffaella, Chisari, Clara, Clerici, Raffaella, Clerico, Marinella, Cola, Gaia, Conte, Antonella, Conti, Marta Zaffira, Cordano, Christian, Cordera, Susanna, Corea, Francesco, Correale, Claudio, Cottone, Salvatore, Crescenzo, Francesco, Curti, Erica, dʼAmbrosio, Alessandro, DʼAmico, Emanuele, Danni, Maura Chiara, dʼArma, Alessia, Dattola, Vincenzo, de Biase, Stefano, Luca, Giovanna De, Mercanti, Stefania Federica De, De Mitri, Paolo, De Stefano, Nicola, Cava, Marco Della, Napoli, Mario di, Sapio, Alessia Di, Docimo, Renato, Dutto, Anna, Evangelista, Luana, Fanara, Salvatore, Diana, Ferraro, Ferrò, Maria Teresa, Fioretti, Cristina, Fratta, Mario, Frau, Jessica, Fronza, Marzia, Furlan, Roberto, Gajofatto, Alberto, Gallo, Antonio, Gallo, Paolo, Gasperini, Claudio, Ghazaryan, Anna, Giometto, Bruno, Gobbin, Francesca, Govone, Flora, Granella, Franco, Grange, Erica, Grasso, Maria Grazia, Guareschi, Angelica, Guaschino, Clara, Guerrieri, Simone, Guidetti, Donata, Iaffaldano, Pietro, Ianniello, Antonio, Iasevoli, Luigi, Imperiale, Daniele, Infante, Maria Teresa, Iodice, Rosa, Iovino, Aniello, Konrad, Giovanna, Landi, Doriana, Lanzillo, Roberta, Lapucci, Caterina, Lavorgna, Luigi, LʼEpiscopo, Maria Rita, Leva, Serena, Liberatore, Giuseppe, Lo Re, Marianna, Longoni, Marco, Lopiano, Leonardo, Lorefice, Lorena, Lucchini, Matteo, Lus, Giacomo, Maimone, Davide, Malentacchi, Maria, Mallucci, Giulia, Malucchi, Simona, Mancinelli, Chiara Rosa, Mancinelli, Luca, Manganotti, Paolo, Maniscalco, Giorgia Teresa, Mantero, Vittorio, Marangoni, Sabrina, Marastoni, Damiano, Marinelli, Fabiana, Marti, Alessandro, Boneschi, Filippo Martinelli, Masserano Zoli, Federco, Matta, Francesca, Mendozzi, Laura, Meucci, Giuseppe, Miante, Silvia, Miele, Giuseppina, Milano, Eva, Mirabella, Massimiliano, Missione, Rosanna, Moccia, Marcello, Moiola, Lucia, Montepietra, Sara, MontiBragadin, Margherita, Montini, Federico, Motta, Roberta, Nardone, Raffaele, Nicoletti, Carolina Gabri, Nobile-Orazio, Eduardo, Nozzolillo, Agostino, Onofrj, Marco, Orlandi, Riccardo, Palmieri, Anna, Paolicelli, Damiano, Pasquali, Livia, Pastò, Luisa, Pedrazzoli, Elisabetta, Petracca, Maria, Petrone, Alfredo, Piantadosi, Carlo, Pietroboni, Anna M, Pinardi, Federica, Ponzano, Marta, Portaccio, Emilio, Pozzato, Mattia, Pozzilli, Carlo, Prosperini, Luca, Protti, Alessandra, Ragonese, Paolo, Rasia, Sarah, Realmuto, Sabrina, Repice, Anna, Rigoni, Eleonora, Rilla, Maria Teresa, Rinaldi, Francesca, Romano, Calogero Marcello, Ronzoni, Marco, Rovaris, Marco, Ruscica, Francesca, Sabattini, Loredana, Salemi, Giuseppe, Saraceno, Lorenzo, Sartori, Alessia, Sartori, Arianna, Sbragia, Elvira, Scarano, Giuditta Ilaria, Scarano, Valentina, Schillaci, Valentina, Sessa, Maria, Sgarito, Caterina, Sibilia, Grazia, Siciliano, Gabriele, Signori, Alessio, Signoriello, Elisabetta, Sinisi, Leonardo, Sireci, Francesca, Sola, Patrizia, Solaro, Claudio, Sotgiu, Stefano, Sparaco, Maddalena, Stromillo, Maria Laura, Strumia, Silvia, Susani, Emanuela Laura, Tabiadon, Giulietta, Teatini, Francesco, Tomassini, Valentina, Tonietti, Simone, Torri, Clerici Valentina, Tortorella, Carla, Toscano, Simona, Totaro, Rocco, Trotta, Maria, Turano, Gabriella, Ulivelli, Monica, Valentino, Manzo, Vaula, Giovanna, Vecchio, Domizia, Vercellino, Marco, Verrengia, Elena Pinuccia, Vianello, Marika, Virgilio, Eleonora, Vitetta, Francesca, Vollaro, Stefano, Zaffaroni, Mauro, Zampolini, Mauro, Zarbo, Ignazio Roberto, and Zuliani, Luigi

Published
2022
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24. Acoustic Emission Monitoring as a Non-invasive Tool to Assist the Conservator in the Reactivation and Maintenance of Historical Vehicle Engines.

Author

Chalançon, Brice, Roda-Buch, Alejandro, Cornet, Emilie, Rapp, Guillaume, Weisser, Thomas, and Brambilla, Laura

Subjects
ACOUSTIC emission, AUTOMOBILE museums, ENGINES, INTERNAL combustion engines
Abstract

Historical cars are an important part of the cultural heritage of the last 150 years. Their preservation in technical museums raises the question of how to preserve their primary functionality, namely their mobility. This implies being able to reactivate and to maintain their thermal engines, which are the source of their motion. However, the diversity and complexity of these engines generally require the presence of highly qualified personnel as well as detailed condition reports to assist the conservators. This study proposes to use acoustic emission techniques to facilitate these conservation procedures by objectifying the evaluation of the state of the engines and by providing systematic quantitative indicators for their health monitoring. To illustrate the implementation and the potentialities of this approach, different tests have been carried out at the National Automobile Museum of Mulhouse, on a Renault Type AG1. A dedicated experimental setup and the associated measurement protocol are presented in this paper. The derived results show the ability of this method to detect specific types of engine malfunctions, both during bench test and in situ measurement conditions. A critical discussion is finally proposed to highlight the feasibility and the possibilities of such laboratory techniques in the context of conservation assistance. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Non Clinical Model to Assess the Mechanism of Action of a Combined Hyaluronic Acid, Chondroitin Sulfate and Calcium Chloride: HA+CS+CaCl2 Solution on a 3D Human Reconstructed Bladder Epithelium.

Author

Brambilla, Laura, Frangione, Valeria, and Meloni, Marisa

Subjects
PERMEATION tubes, INTRAVESICAL administration, CHONDROITIN sulfates, CALCIUM chloride, ESCHERICHIA coli, CALCIUM sulfate, HYALURONIC acid
Abstract

Purpose: Medical Device Regulation (EU) 2017/745 requires the principal mode of action (MoA) to be demonstrated by experimental data. The MoA of Ialuril® Prefill (combined as HA+CS+CaCl2: sodium hyaluronate 1.6%, sodium chondroitin sulphate 2% w/v and calcium chloride 0.87%) Class III medical device, indicated for intravesical instillation to reduce urinary tract infections, has been evaluated on a 3D reconstructed human bladder epithelium (HBE).Methods: Three experimental designs; i) E. coli strain selection (DSM 103538, DSM 1103) to investigate the HA+CS+CaCl2 properties in modifying bacterial growth in liquid broth (CFU 4h and 24h) at 80%, 50% and 25% concentrations; ii) evaluation of film forming properties on HBE after 15 min exposure by quantifying caffeine permeation across the epithelium; iii) capacity to counteract E. coli adhesion and biofilm formation on colonized HBE by viable counts and ultrastructural analysis by scanning electron microscopy (SEM) using ciprofloxacin as the reference antimicrobial molecule.Results: No significant differences were observed in bacterial viability for both the E. coli strains. HA+CS+CaCl2 reduced caffeine permeation of 51.7% and 38.1% at 1h and 2h, respectively and determined a significant decrease in caffeine permeation rate at both timepoints supporting HA+CS+CaCl2 capacity to firmly adhere to the bladder epithelium creating a physical barrier on the surface. The viable counts in HBE treated tissues then infected with E. coli resulted not different from the negative control suggesting that the device did not inhibit E. coli growth. SEM images showed homogenous product distribution over the HBE surface and confirmed the capacity of HA+CS+CaCl2 to adhere to the bladder epithelium, counteracting biofilm formation.Conclusion: The results support the capacity of HA+CS+CaCl2 to counteract bacterial invasion by using a physico-mechanical mode of action: this medical device represents a valid alternative to antibiotics in the treatment of recurrent UTIs. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Clinical characteristics and outcomes of inpatients with neurologic disease and COVID-19 in Brescia, Lombardy, Italy

Author

Benussi, Alberto, Pilotto, Andrea, Premi, Enrico, Libri, Ilenia, Giunta, Marcello, Agosti, Chiara, Alberici, Antonella, Baldelli, Enrico, Benini, Matteo, Bonacina, Sonia, Brambilla, Laura, Caratozzolo, Salvatore, Cortinovis, Matteo, Costa, Angelo, Cotti Piccinelli, Stefano, Cottini, Elisabetta, Cristillo, Viviana, Delrio, Ilenia, Filosto, Massimiliano, Gamba, Massimo, Gazzina, Stefano, Gilberti, Nicola, Gipponi, Stefano, Imarisio, Alberto, Invernizzi, Paolo, Leggio, Ugo, Leonardi, Matilde, Liberini, Paolo, Locatelli, Martina, Masciocchi, Stefano, Poli, Loris, Rao, Renata, Risi, Barbara, Rozzini, Luca, Scalvini, Andrea, Schiano di Cola, Francesca, Spezi, Raffaella, Vergani, Veronica, Volonghi, Irene, Zoppi, Nicola, Borroni, Barbara, Magoni, Mauro, Pezzini, Alessandro, and Padovani, Alessandro

Published
2020
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27. Investigating five totalizing counters manufactured by the Alphonse Darras company of the CNAM collections in Paris

Author

Schröter, Julie, Foasso, Cyrille, Bellot-Gurlet, Ludovic, and Brambilla, Laura

Subjects
Transparent lacquers, Fluorescência UV, Copper alloys, Non-invasive methods, Lacas transparentes, FTIR, Métodos não invasivos, Séculos XIX-XX, Ligas de cobre, UV fluorescence, 19th-20th century
Abstract

The paper reports the study of five totalizing counters preserved in the collections of the CNAM (museum of the French National Conservatory of Arts and Crafts) in Paris. These artefacts are part of a corpus of over forty counters attributed to the Darras company founded by engineer Alphonse Darras (1860-1936). In the framework of the LacCA project at Haute Ecole Arc, Neuchâtel (Switzerland), dedicated to the characterization of lacquered copper-alloys, our attention was drawn to the different aspects of the object’s coatings. Lacquers were frequently applied to technical objects to both protect them from corrosion and provide an esthetical appearance. Five totalizing counters showing various typologies and surface colours were chosen from the set and explored by a non-invasive multi analytical approach. The comparative study – investigating lacquering processes and materials - contributes to the historical study of these artefacts., Este artigo descreve o estudo de cinco contadores totalizadores conservados nas coleções do CNAM (museu do Conservatoire National des Arts et Métiers) em Paris. Estes artefactos fazem parte de um corpus de mais de 40 contadores atribuídos à empresa Darras, fundada pelo engenheiro Alphonse Darras (1860-1936). O estudo desenvolvido no âmbito do projecto LacCA da Haute Ecole Arc, Neuchâtel (Suíça) sobre caracterização de ligas de cobre lacadas, incidiu sobre as diferentes características dos revestimentos dos objetos. As lacas eram frequentemente aplicadas em objetos técnicos com o duplo intuito de proteção contra a corrosão e decoração. Cinco contadores totalizadores com diferentes formas e cores, foram selecionados e examinados através de diferentes técnicas analíticas não invasivas. O estudo comparativo – investigando os processos e os materiais de lacagem – contribui para o estudo histórico destes artefactos.

Published
2023

29. Prognostic relevance of quantitative and longitudinal MOG antibody testing in patients with MOGAD: a multicentre retrospective study

Author

Gastaldi, Matteo, Foiadelli, Thoma, Greco, Giacomo, Scaranzin, Silvia, Rigoni, Eleonora, Masciocchi, Stefano, Ferrari, Sergio, Mancinelli, Chiara, Brambilla, Laura, Mancardi, Margherita, Giacomini, Thea, Ferraro, Diana, Della Corte, Marida, Gallo, Antonio, Di Filippo, Massimiliano, Benedetti, Luana, Novi, Giovanni, Versino, Maurizio, Banfi, Paola, Iorio, Raffaele, Moiola, Lucia, Turco, Emanuela, Sartori, Stefano, Nosadini, Margherita, Ruggieri, Martino, Savasta, Salvatore, Colombo, Elena, Ballante, Elena, Jarius, Sven, Mariotto, Sara, Franciotta, Diego, Iorio, Raffaele (ORCID:0000-0002-6270-0956), Gastaldi, Matteo, Foiadelli, Thoma, Greco, Giacomo, Scaranzin, Silvia, Rigoni, Eleonora, Masciocchi, Stefano, Ferrari, Sergio, Mancinelli, Chiara, Brambilla, Laura, Mancardi, Margherita, Giacomini, Thea, Ferraro, Diana, Della Corte, Marida, Gallo, Antonio, Di Filippo, Massimiliano, Benedetti, Luana, Novi, Giovanni, Versino, Maurizio, Banfi, Paola, Iorio, Raffaele, Moiola, Lucia, Turco, Emanuela, Sartori, Stefano, Nosadini, Margherita, Ruggieri, Martino, Savasta, Salvatore, Colombo, Elena, Ballante, Elena, Jarius, Sven, Mariotto, Sara, Franciotta, Diego, and Iorio, Raffaele (ORCID:0000-0002-6270-0956)

Abstract

Background IgG antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) define a subset of associated disorders (myelin oligodendrocyte glycoprotein associated disorders (MOGAD)) that can have a relapsing course. However, information on relapse predictors is scarce. The utility of retesting MOG-IgG over time and measuring their titres is uncertain. We aimed to evaluate the clinical relevance of longitudinal MOG-IgG titre measurement to predict relapses in patients with MOGAD. Methods In this retrospective multicentre Italian cohort study, we recruited patients with MOGAD and available longitudinal samples (at least one >3 months after disease onset) and tested them with a live cell-based assay with endpoint titration (1:160 cut-off). Samples were classified as € attack' (within 30 days since a disease attack (n=59, 17%)) and € remission' (≥31 days after attack (n=295, 83%)). Results We included 102 patients with MOGAD (57% adult and 43% paediatric) with a total of 354 samples (83% from remission and 17% from attack). Median titres were higher during attacks (1:1280 vs 1:640, p=0.001). Median onset titres did not correlate with attack-related disability, age or relapses. Remission titres were higher in relapsing patients (p=0.02). When considering the first remission sample available for each patient, titres >1:2560 were predictors of relapsing course in survival (log rank, p<0.001) and multivariate analysis (p<0.001, HR: 10.9, 95% CI 3.4 to 35.2). MOG-IgG seroconversion to negative was associated with a 95% relapse incidence rate reduction (incidence rate ratio: 0.05, p<0.001). Conclusions Persistent MOG-IgG positivity and high remission titres are associated with an increased relapse risk. Longitudinal MOG-IgG titres could be useful to stratify patients to be treated with long term immunosuppression. © 2023 Authors. All rights reserved

Published
2023

33. Prognostic relevance of quantitative and longitudinal MOG antibody testing in patients with MOGAD: a multicentre retrospective study

Author

Gastaldi, Matteo, primary, Foiadelli, Thomas, additional, Greco, Giacomo, additional, Scaranzin, Silvia, additional, Rigoni, Eleonora, additional, Masciocchi, Stefano, additional, Ferrari, Sergio, additional, Mancinelli, Chiara, additional, Brambilla, Laura, additional, Mancardi, Margherita, additional, Giacomini, Thea, additional, Ferraro, Diana, additional, Della Corte, Marida, additional, Gallo, Antonio, additional, Di Filippo, Massimiliano, additional, Benedetti, Luana, additional, Novi, Giovanni, additional, Versino, Maurizio, additional, Banfi, Paola, additional, Iorio, Raffaele, additional, Moiola, Lucia, additional, Turco, Emanuela, additional, Sartori, Stefano, additional, Nosadini, Margherita, additional, Ruggieri, Martino, additional, Savasta, Salvatore, additional, Colombo, Elena, additional, Ballante, Elena, additional, Jarius, Sven, additional, Mariotto, Sara, additional, and Franciotta, Diego, additional

Published
2022
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34. Revealing Degradation Patterns: Imaging Techniques for the Study of Metal Soap Formation on Painted Metal Objects

Author

Russo, Silvia, Joseph, Edith, Thomas, Jean Baptiste, and Brambilla, Laura

Subjects
imaging, painted metals, metal conservation, metal carboxylates, metal soaps
Abstract

In attempting to document the degradation processes occurring on cultural heritage objects, imaging-based analytical techniques present many advantages, as they provide spatial and spectral information and allow the simultaneous investigation of the chemical and morphological characteristics of a sample. This study presents a protocol based on chemical imaging – Fourier transform infrared microspectroscopy (μ-FTIR) and hyperspectral imaging (HSI) – aimed at monitoring the formation of metal soaps on model metal coupons. Oil-painted metal supports are in fact not immune to degradation due to metal soaps formation, a phenomenon that affects all oil-painted surfaces from the initial curing of the paint film. Copper and zinc sheets were coated with cold-pressed linseed oil and artificially aged for one month in order to instigate the formation of metal soaps. Their reaction was then monitored by means of µ-FTIR. The chemical maps showed an increasing trend over time, elucidating some aspects and differences in the mechanism of formation of the organic salts for the two metal substrates. Additionally, the samples were analysed using two hyperspectral cameras, operating in the visible-near infrared and short-wave infrared spectral range. The appropriateness of the two cameras in the investigation of metal soaps, and the effect of the thickness of the coating on the data obtained, is discussed here.

Published
2022
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35. Reflectance Transformation Imaging Feature Maps for Visual Documentation of Metal Objects

Author

Siatou, Amalia, Alamin Mansouri, Degrigny, Christian, Le Goïc, Gaëtan, Brambilla, Laura, and Nurit, Marvin

Subjects
feature maps, condition assessment, monitoring cleaning, reflectance transformation imaging (RTI), surface documentation
Abstract

Visual documentation plays a key role in cultural heritage preservation, especially in condition assessment, recording, and monitoring of objects. This research aims at detecting and documenting surface changes on cultural heritage metal objects by employing reflectance transformation imaging (RTI). The objective is to use technological advances in the application of RTI for automated visual documentation of historical metal surfaces. The proposed methodology examines how new algorithms developed to process raw RTI data can be applied to study surface appearance attributes as a function of their angular reflectance. Through visualization of geometric or statistical surface features, global characterization of the appearance attributes and isolation of information are possible. As an illustration of the methodology developed, zinc printing plates exhibiting localized corrosion were examined in terms of condition assessment and surface cleaning monitoring. Data were acquired by employing monochromatic acquisitions using a dome with fully calibrated and motorized functions. Selected features of the surface parameters were then visualized as feature maps. These maps were compared to common RTI visualization methods based on relighting and studying the surface normal. Examination and interpretation of the results indicated that feature maps can provide an enhanced visualization of surface information in comparison to commonly used methods. Geometric maps mainly contain information about the surface topography, whereas statistical maps principally provide information related to changes in the surface reflectance response and thus can separate differences in the light reflection between a metal substrate and its corrosion products. The combination of the extracted information enhances the visualization of an object’s condition and allows the creation of accurate cartographies.&nbsp

Published
2022
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36. A Methodological Approach for Multi-Temporal Tracking of Silver Tarnishing

Author

Siatou, Amalia, Yuly Castro, Nurit, Marvin, Chatoux, Hermine, Le Goïc, Gaetan, Degrigny, Christian, Brambilla, Laura, and Mansouri, Alamin

Subjects
reflectance transformation imaging, silver tarnishing, multi-temporal data, colourimetry
Abstract

Silver tarnish manifests by changes in the optical properties of the material. Documenting these changes creates many challenges for imaging techniques. This paper proposes a methodological approach based on processing Reflectance Transformation Imaging (RTI) data for tracking multi-temporal changes on such surfaces. Through the statistical analysis of the surface's angular reflectance, information related to the appearance attributes can be evaluated and visualized by maps. Thus, this paper explores the global surface change of the reflectance response of silver tarnishing as a function of time. A qualitative and semi-quantitative evaluation is based on multivariate distance measurements at different time intervals. The results are compared to surface change evaluation by visual inspection, photographic documentation, and colourimetry, practices traditionally used in conservation documentation to monitor surface changes over time. The outcome of this research illustrates the possibilities of RTI data analysis as a tool for accurate multi-temporal documentation of the optical properties changes on specular surfaces.

Published
2022

41. Significance and clinical suggestions for the Somatosensory Evoked Potentials increased in amplitude revealed by a large sample of neurological patients

Author

Rossi Sebastiano, Davide, primary, Cazzato, Daniele, additional, Visani, Elisa, additional, Dalla Bella, Eleonora, additional, Brambilla, Laura, additional, Devigili, Grazia, additional, Caroppo, Paola, additional, Maggi, Lorenzo, additional, Nanetti, Lorenzo, additional, Salsano, Ettore, additional, Canafoglia, Laura, additional, Canavero, Isabella, additional, Anghileri, Elena, additional, Bonfoco, Deborah, additional, and Lanteri, Paola, additional

Published
2022
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43. Anti-Spike IgG in multiple sclerosis patients after BNT162b2 vaccine: An exploratory case-control study in Italy

Author

Giossi, Riccardo, primary, Consonni, Alessandra, additional, Torri Clerici, Valentina, additional, Zito, Antonio, additional, Rigoni, Eleonora, additional, Antozzi, Carlo, additional, Brambilla, Laura, additional, Crisafulli, Sebastiano Giuseppe, additional, Bellino, Antonella, additional, Frangiamore, Rita, additional, Bonanno, Silvia, additional, Vanoli, Fiammetta, additional, Ciusani, Emilio, additional, Corsini, Elena, additional, Andreetta, Francesca, additional, Baggi, Fulvio, additional, Tramacere, Irene, additional, Mantegazza, Renato, additional, Conte, Antonella, additional, Bergamaschi, Roberto, additional, and Confalonieri, Paolo, additional

Published
2022
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44. Italian multicenter observational study on real-life experience with alemtuzumab in naïve patients with aggressive multiple sclerosis

Author

Moiola, Lucia, Zanetta, Chiara, Di Cristinzi, Maria, Nozzolillo, Agostino, Rinaldi, Francesca, Brambilla, Laura, Annovazzi, Pietro, Lus, Giacomo, Puorro, Giorgia, Frau, Jessica, Malucchi, Simona, Bianco, Assunta, Lapucci, Caterina, Marfia, Girolama, Gallo, Antonio, Cerqua, Raffaella, Cavalla, Paola, and Filippi, Massimo

Published
2021
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46. A real‐world study of alemtuzumab in a cohort of Italian patients

Author

Russo, Cinzia Valeria, primary, Saccà, Francesco, additional, Frau, Jessica, additional, Annovazzi, Pietro, additional, Signoriello, Elisabetta, additional, Bonavita, Simona, additional, Grasso, Roberta, additional, Clerico, Marinella, additional, Cordioli, Cinzia, additional, Laroni, Alice, additional, Capobianco, Marco, additional, Torri Clerici, Valentina, additional, Sartori, Arianna, additional, Cavalla, Paola, additional, Maniscalco, Giorgia Teresa, additional, La Gioia, Sara, additional, Caleri, Francesca, additional, Giugno, Alessia, additional, Iodice, Rosa, additional, Carotenuto, Antonio, additional, Cocco, Eleonora, additional, Fenu, Giuseppe, additional, Zaffaroni, Mauro, additional, Baroncini, Damiano, additional, Lus, Giacomo, additional, Gallo, Antonio, additional, De Mercanti, Stefania Federica, additional, Lapucci, Caterina, additional, Di Francescantonio, Valeria, additional, Brambilla, Laura, additional, Sormani, Maria Pia, additional, and Signori, Alessio, additional

Published
2021
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47. SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study

Author

Sormani, Maria Pia, primary, Schiavetti, Irene, additional, Landi, Doriana, additional, Carmisciano, Luca, additional, De Rossi, Nicola, additional, Cordioli, Cinzia, additional, Moiola, Lucia, additional, Radaelli, Marta, additional, Immovilli, Paolo, additional, Capobianco, Marco, additional, Brescia Morra, Vincenzo, additional, Trojano, Maria, additional, Tedeschi, Gioacchino, additional, Comi, Giancarlo, additional, Battaglia, Mario Alberto, additional, Patti, Francesco, additional, Fragoso, Yara Dadalti, additional, Sen, Sedat, additional, Siva, Aksel, additional, Furlan, Roberto, additional, Salvetti, Marco, additional, Abbadessa, Gianmarco, additional, Aguglia, Umberto, additional, Allegorico, Lia, additional, Allegri, Rossi Beatrice Maria, additional, Amato, Maria Pia, additional, Annovazzi, Pietro, additional, Antozzi, Carlo, additional, Appendino, Lucia, additional, Arena, Sebastiano, additional, Baione, Viola, additional, Balgera, Roberto, additional, Barcella, Valeria, additional, Baroncini, Damiano, additional, Barrilà, Caterina, additional, Battaglia, Mario A., additional, Bellacosa, Alessandra, additional, Bellucci, Gianmarco, additional, Bergamaschi, Roberto, additional, Bergamaschi, Valeria, additional, Bezzini, Daiana, additional, Biolzi, Beatrice, additional, Bisecco, Alvino, additional, Bonavita, Simona, additional, Borriello, Giovanna, additional, Bosa, Chiara, additional, Bosco, Antonio, additional, Bovis, Francesca, additional, Bozzali, Marco, additional, Brambilla, Laura, additional, Brescia, Morra Vincenzo, additional, Brichetto, Giampaolo, additional, Buccafusca, Maria, additional, Bucciantini, Elisabetta, additional, Bucello, Sebastiano, additional, Buscarinu, Maria Chiara, additional, Cabboi, Maria Paola, additional, Calabrese, Massimiliano, additional, Calabria, Francesca, additional, Caleri, Francesca, additional, Camilli, Federico, additional, Caniatti, Luisa Maria, additional, Cantello, Roberto, additional, Capra, Ruggero, additional, Capuano, Rocco, additional, Carta, Patrizia, additional, Cavalla, Paola, additional, Celani, Maria Grazia, additional, Cellerino, Maria, additional, Cerqua, Raffaella, additional, Chisari, Clara, additional, Clerici, Raffaella, additional, Clerico, Marinella, additional, Cocco, Eleonora, additional, Cola, Gaia, additional, Confalonieri, Paolo, additional, Conte, Antonella, additional, Conti, Marta Zaffira, additional, Cordano, Christian, additional, Cordera, Susanna, additional, Corea, Francesco, additional, Correale, Claudio, additional, Cottone, Salvatore, additional, Crescenzo, Francesco, additional, Curti, Erica, additional, d’Ambrosio, Alessandro, additional, D’Amico, Emanuele, additional, Danni, Maura Chiara, additional, d’Arma, Alessia, additional, Dattola, Vincenzo, additional, de Biase, Stefano, additional, De Luca, Giovanna, additional, De Mercanti, Stefania Federica, additional, De Mitri, Paolo, additional, De Stefano, Nicola, additional, Della Cava, Marco, additional, di Napoli, Mario, additional, Di Sapio, Alessia, additional, Docimo, Renato, additional, Dutto, Anna, additional, Evangelista, Luana, additional, Fanara, Salvatore, additional, Ferraro, Diana, additional, Ferrò, Maria Teresa, additional, Filippi, Massimo, additional, Fioretti, Cristina, additional, Fratta, Mario, additional, Frau, Jessica, additional, Fronza, Marzia, additional, Gajofatto, Alberto, additional, Gallo, Antonio, additional, Gallo, Paolo, additional, Gasperini, Claudio, additional, Ghazaryan, Anna, additional, Giometto, Bruno, additional, Gobbin, Francesca, additional, Govone, Flora, additional, Granella, Franco, additional, Grange, Erica, additional, Grasso, Maria Grazia, additional, Guareschi, Angelica, additional, Guaschino, Clara, additional, Guerrieri, Simone, additional, Guidetti, Donata, additional, Iaffaldano, Pietro, additional, Ianniello, Antonio, additional, Iasevoli, Luigi, additional, Imperiale, Daniele, additional, Infante, Maria Teresa, additional, Inglese, Matilde, additional, Iodice, Rosa, additional, Iovino, Aniello, additional, Konrad, Giovanna, additional, Lanzillo, Roberta, additional, Lapucci, Caterina, additional, Lavorgna, Luigi, additional, L’Episcopo Maria, Rita, additional, Leva, Serena, additional, Liberatore, Giuseppe, additional, Lo Re, Marianna, additional, Longoni, Marco, additional, Lopiano, Leonardo, additional, Lorefice, Lorena, additional, Lucchini, Matteo, additional, Lus, Giacomo, additional, Maimone, Davide, additional, Malentacchi, Maria, additional, Mallucci, Giulia, additional, Malucchi, Simona, additional, Mancinelli, Chiara Rosa, additional, Mancinelli, Luca, additional, Manganotti, Paolo, additional, Maniscalco, Teresa Giorgia, additional, Mantero, Vittorio, additional, Marangoni, Sabrina, additional, Marastoni, Damiano, additional, Marfia, Alessandra Girolama, additional, Marinelli, Fabiana, additional, Marti, Alessandro, additional, Martinelli Boneschi, Filippo, additional, Masserano Zoli, Federco, additional, Matta, Francesca, additional, Mendozzi, Laura, additional, Meucci, Giuseppe, additional, Miante, Silvia, additional, Miele, Giuseppina, additional, Milano, Eva, additional, Mirabella, Massimiliano, additional, Missione, Rosanna, additional, Moccia, Marcello, additional, Montepietra, Sara, additional, Monti Bragadin, Margherita, additional, Montini, Federico, additional, Motta, Roberta, additional, Nardone, Raffaele, additional, Nicoletti, Carolina Gabri, additional, Nobile-Orazio, Eduardo, additional, Nozzolillo, Agostino, additional, Onofrj, Marco, additional, Orlandi, Riccardo, additional, Palmieri, Anna, additional, Paolicelli, Damiano, additional, Pasquali, Livia, additional, Pastò, Luisa, additional, Pedrazzoli, Elisabetta, additional, Perini, Paola, additional, Pesci, Ilaria, additional, Petracca, Maria, additional, Petrone, Alfredo, additional, Piantadosi, Carlo, additional, Pietroboni, Anna M., additional, Pinardi, Federica, additional, Ponzano, Marta, additional, Portaccio, Emilio, additional, Pozzato, Mattia, additional, Pozzilli, Carlo, additional, Prosperini, Luca, additional, Protti, Alessandra, additional, Ragonese, Paolo, additional, Rasia, Sarah, additional, Realmuto, Sabrina, additional, Repice, Anna, additional, Rigoni, Eleonora, additional, Rilla, Maria Teresa, additional, Rinaldi, Francesca, additional, Romano, Calogero Marcello, additional, Ronzoni, Marco, additional, Rovaris, Marco, additional, Ruscica, Francesca, additional, Sabattini, Loredana, additional, Salemi, Giuseppe, additional, Saraceno, Lorenzo, additional, Sartori, Alessia, additional, Sartori, Arianna, additional, Sbragia, Elvira, additional, Scandellari, Cinzia, additional, Scarano Giuditta, Ilaria, additional, Scarano, Valentina, additional, Schillaci, Valentina, additional, Sessa, Maria, additional, Sgarito, Caterina, additional, Sibilia, Grazia, additional, Siciliano, Gabriele, additional, Signori, Alessio, additional, Signoriello, Elisabetta, additional, Sinisi, Leonardo, additional, Sireci, Francesca, additional, Sola, Patrizia, additional, Solaro, Claudio, additional, Sormani, Maria Pia, additional, Sotgiu, Stefano, additional, Sparaco, Maddalena, additional, Stromillo, Maria Laura, additional, Strumia, Silvia, additional, Susani, Laura Emanuela, additional, Tabiadon, Giulietta, additional, Teatini, Francesco, additional, Tomassini, Valentina, additional, Tonietti, Simone, additional, Torri, Clerici Valentina, additional, Tortorella, Carla, additional, Toscano, Simona, additional, Totaro, Rocco, additional, Trotta, Maria, additional, Turano, Gabriella, additional, Ulivelli, Monica, additional, Valentino, Manzo, additional, Vaula, Giovanna, additional, Vecchio, Domizia, additional, Vercellino, Marco, additional, Verrengia, Elena Pinuccia, additional, Vianello, Marika, additional, Virgilio, Eleonora, additional, Vitetta, Francesca, additional, Vollaro, Stefano, additional, Zaffaroni, Mauro, additional, Zampolini, Mauro, additional, Zarbo, Ignazio Roberto, additional, Zito, Antonio, additional, and Zuliani, Luigi, additional

Published
2021
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