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3. Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients

Author

Oldenburg, Bas, van Wijk, Femke, Brand, Eelco C., Honkoop, Pieter, Jacobs, Rutger J., Ponsioen, Cyriel Y., de Boer, Nanne K.H., Alderlieste, Yasser A., van Herwaarden, Margot A., van Tuyl, Sebastiaan A.C., Lutgens, Maurice W., Janneke van der Woude, C., Mares, Wout G.M., de Koning, Daan B., Bosman, Joukje H., Vecht, Juda, de Schryver, Anneke M.P., van der Meulen-de Jong, Andrea E., Pierik, Marieke J., Boekema, Paul J., Verburg, Robert J., Jharap, Bindia, Willemsen, Gonneke, Boomsma, Dorret I., Jansen, Jeroen M., Stokkers, Pieter C.F., Hoentjen, Frank, Quispel, Rutger, Horjus Talabur Horje, Carmen S., van de Meeberg, Paul C., Mahmmod, Nofel, West, Rachel L., Willems, Marleen, Minderhoud, Itta M., Fidder, Herma H., van Schaik, Fiona D.M., Hirdes, Meike M.C., Boontje, Nynke A., Müskens, Bart L.M., Weersma, Rinse K., Romberg-Camps, Marielle J.L., Klaassen, Marjolein A.Y., Gacesa, Ranko, Vich Vila, Arnau, Ghosh, Hiren, de Zoete, Marcel R., Fu, Jingyuan, Wijmenga, Cisca, and Zhernakova, Alexandra more...

Published
2021
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5. Systematic Review and External Validation of Prediction Models Based on Symptoms and Biomarkers for Identifying Endoscopic Activity in Crohn's Disease

Author

Brand, Eelco C., Elias, Sjoerd G., Minderhoud, Itta M., van der Veen, Julius J., Baert, Filip J., Laharie, David, Bossuyt, Peter, Bouhnik, Yoram, Buisson, Anthony, Lambrecht, Guy, Louis, Edouard, Pariente, Benjamin, Pierik, Marieke J., van der Woude, C. Janneke, D’Haens, Geert R.A. M., Vermeire, Séverine, and Oldenburg, Bas more...

Published
2020
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13. Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor colitis

Author

Cancer, MS Medische Oncologie, CTI Van Wijk, Infection & Immunity, MS MDL 1, CMM, CMM Groep Vercoulen, Pathologie Pathologen staf, CTI Eijkelkamp, CTI Bont, CTI Computational Immunology Core, CTI Research, Child Health, van Eijs, Mick J.M., ter Linde, José J.M., Baars, Matthijs J.D., Amini, Mojtaba, Laclé, Miangela M., Brand, Eelco C., Delemarre, Eveline M., Drylewicz, Julia, Nierkens, Stefan, Verheijden, Rik J., Oldenburg, Bas, Vercoulen, Yvonne, Suijkerbuijk, Karijn P.M., van Wijk, Femke, Cancer, MS Medische Oncologie, CTI Van Wijk, Infection & Immunity, MS MDL 1, CMM, CMM Groep Vercoulen, Pathologie Pathologen staf, CTI Eijkelkamp, CTI Bont, CTI Computational Immunology Core, CTI Research, Child Health, van Eijs, Mick J.M., ter Linde, José J.M., Baars, Matthijs J.D., Amini, Mojtaba, Laclé, Miangela M., Brand, Eelco C., Delemarre, Eveline M., Drylewicz, Julia, Nierkens, Stefan, Verheijden, Rik J., Oldenburg, Bas, Vercoulen, Yvonne, Suijkerbuijk, Karijn P.M., and van Wijk, Femke more...

Published
2023

14. Compartment-driven imprinting of intestinal CD4 T cells in inflammatory bowel disease and homeostasis

Author

Infection & Immunity, CTI Van Wijk, MS MDL 1, Cancer, Child Health, Lutter, Lisanne, Ter Linde, José J M, Brand, Eelco C, Hoytema van Konijnenburg, David P, Roosenboom, Britt, Talabur-Horje, Carmen Horjus, Oldenburg, Bas, van Wijk, Femke, Infection & Immunity, CTI Van Wijk, MS MDL 1, Cancer, Child Health, Lutter, Lisanne, Ter Linde, José J M, Brand, Eelco C, Hoytema van Konijnenburg, David P, Roosenboom, Britt, Talabur-Horje, Carmen Horjus, Oldenburg, Bas, and van Wijk, Femke more...

Published
2023

15. Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor induced colitis

Author

van Eijs, Mick J.M., primary, ter Linde, José J.M., additional, Baars, Matthijs J.D., additional, Amini, Mojtaba, additional, Laclé, Miangela M., additional, Brand, Eelco C., additional, Delemarre, Eveline M., additional, Drylewicz, Julia, additional, Nierkens, Stefan, additional, Verheijden, Rik J., additional, Oldenburg, Bas, additional, Vercoulen, Yvonne, additional, Suijkerbuijk, Karijn P.M., additional, and van Wijk, Femke, additional more...

Published
2023
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17. Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint

Author

Infection & Immunity, CTI Van Wijk, Unit Opleiding Aios, CTI Van Loosdregt, Immuno/reuma onderzoek 1 (Vastert), Immunologie/Reumatologie, Child Health, Immuno/reuma onderzoek 5 (Vastert2), CTI Research, Immuno/reuma onderzoek 3 (Loosdregt), Lutter, Lisanne, van der Wal, M Marlot, Brand, Eelco C, Maschmeyer, Patrick, Vastert, Sebastiaan, Mashreghi, Mir-Farzin, van Loosdregt, Jorg, van Wijk, Femke, Infection & Immunity, CTI Van Wijk, Unit Opleiding Aios, CTI Van Loosdregt, Immuno/reuma onderzoek 1 (Vastert), Immunologie/Reumatologie, Child Health, Immuno/reuma onderzoek 5 (Vastert2), CTI Research, Immuno/reuma onderzoek 3 (Loosdregt), Lutter, Lisanne, van der Wal, M Marlot, Brand, Eelco C, Maschmeyer, Patrick, Vastert, Sebastiaan, Mashreghi, Mir-Farzin, van Loosdregt, Jorg, and van Wijk, Femke more...

Published
2022

20. Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients

Author

Brand, Eelco C., primary, Klaassen, Marjolein A.Y., additional, Gacesa, Ranko, additional, Vich Vila, Arnau, additional, Ghosh, Hiren, additional, de Zoete, Marcel R., additional, Boomsma, Dorret I., additional, Hoentjen, Frank, additional, Horjus Talabur Horje, Carmen S., additional, van de Meeberg, Paul C., additional, Willemsen, Gonneke, additional, Fu, Jingyuan, additional, Wijmenga, Cisca, additional, van Wijk, Femke, additional, Zhernakova, Alexandra, additional, Oldenburg, Bas, additional, Weersma, Rinse K., additional, Brand, Eelco C., additional, Honkoop, Pieter, additional, Jacobs, Rutger J., additional, Ponsioen, Cyriel Y., additional, de Boer, Nanne K.H., additional, Alderlieste, Yasser A., additional, van Herwaarden, Margot A., additional, van Tuyl, Sebastiaan A.C., additional, Lutgens, Maurice W., additional, Janneke van der Woude, C., additional, Mares, Wout G.M., additional, de Koning, Daan B., additional, Bosman, Joukje H., additional, Vecht, Juda, additional, de Schryver, Anneke M.P., additional, van der Meulen-de Jong, Andrea E., additional, Pierik, Marieke J., additional, Boekema, Paul J., additional, Verburg, Robert J., additional, Jharap, Bindia, additional, Jansen, Jeroen M., additional, Stokkers, Pieter C.F., additional, Quispel, Rutger, additional, Mahmmod, Nofel, additional, West, Rachel L., additional, Willems, Marleen, additional, Minderhoud, Itta M., additional, Fidder, Herma H., additional, van Schaik, Fiona D.M., additional, Hirdes, Meike M.C., additional, Boontje, Nynke A., additional, Müskens, Bart L.M., additional, and Romberg-Camps, Marielle J.L., additional more...

Published
2021
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22. Human regulatory T cells locally differentiate and are functionally heterogeneous within the inflamed arthritic joint.

Author

Lutter, Lisanne, van der Wal, M Marlot, Brand, Eelco C, Maschmeyer, Patrick, Vastert, Sebastiaan, Mashreghi, Mir‐Farzin, van Loosdregt, Jorg, and van Wijk, Femke

Subjects
REGULATORY T cells, JOINT pain, JUVENILE idiopathic arthritis, SYNOVIAL fluid, AUTOIMMUNE diseases, EXPERIMENTAL arthritis
Abstract

Objective: Tregs are crucial for immune regulation, and environment‐driven adaptation of effector (e)Tregs is essential for local functioning. However, the extent of human Treg heterogeneity in inflammatory settings is unclear. Methods: We combined single‐cell RNA‐ and TCR‐sequencing on Tregs derived from three to six patients with juvenile idiopathic arthritis (JIA) to investigate the functional heterogeneity of human synovial fluid (SF)‐derived Tregs from inflamed joints. Confirmation and suppressive function of the identified Treg clusters was assessed by flow cytometry. Results: Four Treg clusters were identified; incoming, activated eTregs with either a dominant suppressive or cytotoxic profile, and GPR56+CD161+CXCL13+ Tregs. Pseudotime analysis showed differentiation towards either classical eTreg profiles or GPR56+CD161+CXCL13+ Tregs supported by TCR data. Despite its most differentiated phenotype, GPR56+CD161+CXCL13+ Tregs were shown to be suppressive. Furthermore, BATF was identified as an overarching eTreg regulator, with the novel Treg‐associated regulon BHLHE40 driving differentiation towards GPR56+CD161+CXCL13+ Tregs, and JAZF1 towards classical eTregs. Conclusion: Our study reveals a heterogeneous population of Tregs at the site of inflammation in JIA. SF Treg differentiate to a classical eTreg profile with a more dominant suppressive or cytotoxic profile that share a similar TCR repertoire, or towards GPR56+CD161+CXCL13+ Tregs with a more distinct TCR repertoire. Genes characterising GPR56+CD161+CXCL13+ Tregs were also mirrored in other T‐cell subsets in both the tumor and the autoimmune setting. Finally, the identified key regulators driving SF Treg adaptation may be interesting targets for autoimmunity or tumor interventions. [ABSTRACT FROM AUTHOR] more...

Published
2022
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23. Homeostatic function and inflammatory activation of ileal CD8+ tissue-resident T cells is dependent on mucosal location

Author

Infection & Immunity, CTI Van Wijk, Unit Opleiding Aios, MS MDL 1, Child Health, Lutter, Lisanne, Roosenboom, Britt, Brand, Eelco C, Ter Linde, José J, Oldenburg, Bas, van Lochem, Ellen G, Horje Talabur Horjus, Carmen S, van Wijk, Femke, Infection & Immunity, CTI Van Wijk, Unit Opleiding Aios, MS MDL 1, Child Health, Lutter, Lisanne, Roosenboom, Britt, Brand, Eelco C, Ter Linde, José J, Oldenburg, Bas, van Lochem, Ellen G, Horje Talabur Horjus, Carmen S, and van Wijk, Femke more...

Published
2021

24. Response to the Comment on 'Meta-analysis of Effect of Volume (Hospital and Operator) on Carotid Revascularization Outcomes'

Author

Opleiding Neurologie, Zorgeenheid Vaatchirurgie Medisch, Unit Opleiding Aios, Cardiovasculaire Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Brain, Regenerative Medicine and Stem Cells, Poorthuis, Michiel H.F., Brand, Eelco C., Halliday, Alison, Bulbulia, Richard, Bots, Michiel L., de Borst, Gert J., Opleiding Neurologie, Zorgeenheid Vaatchirurgie Medisch, Unit Opleiding Aios, Cardiovasculaire Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Brain, Regenerative Medicine and Stem Cells, Poorthuis, Michiel H.F., Brand, Eelco C., Halliday, Alison, Bulbulia, Richard, Bots, Michiel L., and de Borst, Gert J. more...

Published
2021

25. Healthy cotwins share gut microbiome signatures with their inflammatory bowel disease twins and unrelated patients

Author

MS MDL 1, MMB Research line 2, Infection & Immunity, CTI Van Wijk, Child Health, Brand, Eelco C, Klaassen, Marjolein A Y, Gacesa, Ranko, Vila, Arnau Vich, Ghosh, Hiren, de Zoete, Marcel R, Boomsma, Dorret I, Hoentjen, Frank, Horjus Talabur Horje, Carmen S, van de Meeberg, Paul C, Willemsen, Gonneke, Fu, Jingyuan, Wijmenga, Cisca, van Wijk, Femke, Zhernakova, Alexandra, Oldenburg, Bas, Weersma, Rinse K, Dutch TWIN-IBD consortium and the Dutch Initiative on Crohn and Colitis, MS MDL 1, MMB Research line 2, Infection & Immunity, CTI Van Wijk, Child Health, Brand, Eelco C, Klaassen, Marjolein A Y, Gacesa, Ranko, Vila, Arnau Vich, Ghosh, Hiren, de Zoete, Marcel R, Boomsma, Dorret I, Hoentjen, Frank, Horjus Talabur Horje, Carmen S, van de Meeberg, Paul C, Willemsen, Gonneke, Fu, Jingyuan, Wijmenga, Cisca, van Wijk, Femke, Zhernakova, Alexandra, Oldenburg, Bas, Weersma, Rinse K, and Dutch TWIN-IBD consortium and the Dutch Initiative on Crohn and Colitis more...

Published
2021

26. Su510 HEALTHY COTWINS SHARE GUT MICROBIOME SIGNATURES WITH THEIR INFLAMMATORY BOWEL DISEASE TWINS AND UNRELATED PATIENTS

Author

Brand, Eelco C., primary, Klaassen, Marjolein A., additional, Gacesa, Ranko, additional, Vila, Arnau Vich, additional, Ghosh, Hiren, additional, De Zoete, Marcel R., additional, Boomsma, Dorret I., additional, Hoentjen, Frank, additional, Horje, Carmen S. Horjus Talabur, additional, Van De Meeberg, Paul C., additional, Willemsen, A.H., additional, Fu, Jingyuan, additional, Wijmenga, Cisca, additional, Van Wijk, Femke, additional, Zhernakova, Alexandra, additional, Oldenburg, Bas, additional, and Weersma, Rinse K., additional more...

Published
2021
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30. Development of Mucosal PNAd+ and MAdCAM-1+ Venules during Disease Course in Ulcerative Colitis

Author

Roosenboom, Britt, primary, van Lochem, Ellen G., additional, Meijer, Jos, additional, Smids, Carolijn, additional, Nierkens, Stefan, additional, Brand, Eelco C., additional, van Erp, Liselot W., additional, Kemperman, Larissa G.J.M., additional, Groenen, Marcel J.M., additional, Horjus Talabur Horje, Carmen S., additional, and Wahab, Peter J., additional more...

Published
2020
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31. Anti-tumor necrosis factor therapy in patients with inflammatory bowel disease; comorbidity, not patient age, is a predictor of severe adverse events

Author

Zorgeenheid Traumatologie, MS MDL 1, Infection & Immunity, Cancer, Asscher, Vera E R, van der Vliet, Quirine, van der Aalst, Karen, van der Aalst, Anniek, Brand, Eelco C, van der Meulen-de Jong, Andrea E, Oldenburg, Bas, Pierik, Marieke J, van Tuyl, Bas, Mahmmod, Nofel, Maljaars, P W Jeroen, Fidder, Herma H, Dutch ICC, Zorgeenheid Traumatologie, MS MDL 1, Infection & Immunity, Cancer, Asscher, Vera E R, van der Vliet, Quirine, van der Aalst, Karen, van der Aalst, Anniek, Brand, Eelco C, van der Meulen-de Jong, Andrea E, Oldenburg, Bas, Pierik, Marieke J, van Tuyl, Bas, Mahmmod, Nofel, Maljaars, P W Jeroen, Fidder, Herma H, and Dutch ICC more...

Published
2020

32. Development of Mucosal PNAd+ and MAdCAM-1+ Venules during Disease Course in Ulcerative Colitis

Author

CTI Research, CDL Patiëntenzorg MI, Cancer, Infection & Immunity, MS MDL 1, Roosenboom, Britt, Lochem, Ellen G van, Meijer, Jos, Smids, Carolijn, Nierkens, Stefan, Brand, Eelco C, Erp, Liselot W van, Kemperman, Larissa G J M, Groenen, Marcel J M, Horje, Carmen S Horjus Talabur, Wahab, Peter J, CTI Research, CDL Patiëntenzorg MI, Cancer, Infection & Immunity, MS MDL 1, Roosenboom, Britt, Lochem, Ellen G van, Meijer, Jos, Smids, Carolijn, Nierkens, Stefan, Brand, Eelco C, Erp, Liselot W van, Kemperman, Larissa G J M, Groenen, Marcel J M, Horje, Carmen S Horjus Talabur, and Wahab, Peter J more...

Published
2020

33. A systematic review and meta-analysis of complication rates after carotid procedures performed by different specialties

Author

Zorgeenheid Vaatchirurgie Medisch, Verpleegafd Vaatchirurgie D4 Oost, MS MDL 1, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Regenerative Medicine and Stem Cells, Brain, Poorthuis, Michiel H.F., Brand, Eelco C., Halliday, Alison, Bulbulia, Richard, Schermerhorn, Marc L., Bots, Michiel L., de Borst, Gert J., Zorgeenheid Vaatchirurgie Medisch, Verpleegafd Vaatchirurgie D4 Oost, MS MDL 1, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Regenerative Medicine and Stem Cells, Brain, Poorthuis, Michiel H.F., Brand, Eelco C., Halliday, Alison, Bulbulia, Richard, Schermerhorn, Marc L., Bots, Michiel L., and de Borst, Gert J. more...

Published
2020

37. Mo1816 – Prediction of Endoscopic Activity in Patients with Crohn’s Disease – Systematic Review and External Validation of Published Prediction Models

Author

Brand, Eelco C., primary, Elias, Sjoerd G., additional, Minderhoud, Itta M., additional, van der Veen, Julius J., additional, Baert, Filip J., additional, Laharie, David, additional, Bossuyt, Peter, additional, Bouhnik, Yoram, additional, Buisson, Anthony, additional, Lambrecht, Guy, additional, Louis, Edouard, additional, Pariente, Benjamin, additional, Pierik, Marie, additional, Van Der Woude, Christien Janneke, additional, D’Haens, Geert R., additional, Vermeire, Severine, additional, and Oldenburg, Bas, additional more...

Published
2019
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38. This title is unavailable for guests, please login to see more information.

Author

MS MDL 1, Infection & Immunity, Cancer, Schultheiss, Johannes P D, Brand, Eelco C, Lamers, Evert, van den Berg, Willemijn C M, van Schaik, Fiona D M, Oldenburg, Bas, Fidder, Herma H, MS MDL 1, Infection & Immunity, Cancer, Schultheiss, Johannes P D, Brand, Eelco C, Lamers, Evert, van den Berg, Willemijn C M, van Schaik, Fiona D M, Oldenburg, Bas, and Fidder, Herma H more...

Published
2019

42. High Operator and Hospital Volume Are Associated With a Decreased Risk of Death and Stroke After Carotid Revascularization: A Systematic Review and Meta-analysis

Author

Zorgeenheid Vaatchirurgie Medisch, MS MDL 1, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Brain, Poorthuis, Michiel H F, Brand, Eelco C, Halliday, Alison, Bulbulia, Richard, Bots, Michiel L, de Borst, Gert J, Zorgeenheid Vaatchirurgie Medisch, MS MDL 1, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Brain, Poorthuis, Michiel H F, Brand, Eelco C, Halliday, Alison, Bulbulia, Richard, Bots, Michiel L, and de Borst, Gert J more...

Published
2019

43. Response to Comment on 'High Operator and Hospital Volume are Associated With a Decreased Risk of Death and Stroke Following Carotid Revascularization A Systematic Review and Meta-analysis: Authors' Reply'

Author

Zorgeenheid Vaatchirurgie Medisch, MS MDL 1, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Brain, Poorthuis, Michiel H F, Brand, Eelco C, Halliday, Alison, Bulbulia, Richard, Bots, Michiel L, de Borst, Gert J, Zorgeenheid Vaatchirurgie Medisch, MS MDL 1, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Brain, Poorthuis, Michiel H F, Brand, Eelco C, Halliday, Alison, Bulbulia, Richard, Bots, Michiel L, and de Borst, Gert J more...

Published
2019

44. Right-Sided Location Not Associated With Missed Colorectal Adenomas in an Individual-Level Reanalysis of Tandem Colonoscopy Studies

Author

MS MDL 1, Zimmermann-Fraedrich, Katharina, Sehner, Susanne, Rex, Douglas K., Kaltenbach, Tonya, Soetikno, Roy, Wallace, Michael, Leung, Wai K., Guo, Chuanguo, Gralnek, Ian M., Brand, Eelco C., Groth, Stefan, Schachschal, Guido, Ikematsu, Hiroaki, Siersema, Peter D., Roesch, Thomas, MS MDL 1, Zimmermann-Fraedrich, Katharina, Sehner, Susanne, Rex, Douglas K., Kaltenbach, Tonya, Soetikno, Roy, Wallace, Michael, Leung, Wai K., Guo, Chuanguo, Gralnek, Ian M., Brand, Eelco C., Groth, Stefan, Schachschal, Guido, Ikematsu, Hiroaki, Siersema, Peter D., and Roesch, Thomas more...

Published
2019

45. Anti-tumor necrosis factor therapy in patients with inflammatory bowel disease; comorbidity, not patient age, is a predictor of severe adverse events.

Author

Asscher, Vera E. R., van der Vliet, Quirine, van der Aalst, Karen, van der Aalst, Anniek, Brand, Eelco C., van der Meulen-de Jong, Andrea E., Oldenburg, Bas, Pierik, Marieke J., van Tuyl, Bas, Mahmmod, Nofel, Maljaars, P. W. Jeroen, and Fidder, Herma H. more...

Subjects
INFLAMMATORY bowel diseases, OLDER patients, CROHN'S disease, NECROSIS, COMORBIDITY
Abstract

Purpose: To assess safety and effectiveness of anti-tumor necrosis factor (anti-TNF) therapy in IBD patients ≥ 60 years. Methods: Ninety IBD patients ≥ 60 years at initiation of anti-TNF therapy, 145 IBD patients ≥ 60 years without anti-TNF therapy and 257 IBD patients < 60 years at initiation of anti-TNF therapy were retrospectively included in this multicentre study. Primary outcome was the occurrence of severe adverse events (SAEs), serious infections and malignancies. Secondary outcome was effectiveness of therapy. Cox regression analyses were used to assess differences in safety and effectiveness. In safety analyses, first older patients with and without anti-TNF therapy and then older and younger patients with anti-TNF therapy were assessed. Results: In older IBD patients, the use of anti-TNF therapy was associated with serious infections (aHR 3.920, 95% CI 1.185–12.973, p =.025). In anti-TNF-exposed patients, cardiovascular disease associated with serious infections (aHR 3.279, 95% CI 1.098–9.790, p =.033) and the presence of multiple comorbidities (aHR 9.138 (1.248–66.935), p =.029) with malignancies, while patient age did not associate with safety outcomes. Effectiveness of therapy was not affected by age or comorbidity. Conclusion: Older patients receiving anti-TNF therapy have a higher risk of serious infections compared with older IBD patients without anti-TNF therapy, but not compared with younger patients receiving anti-TNF therapy. However, in anti-TNF-exposed patients, comorbidity was found to be an indicator with regards to SAEs. Effectiveness was comparable between older and younger patients. [ABSTRACT FROM AUTHOR] more...

Published
2020
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49. 119 OPTICAL DETECTION OF COLORECTAL NEOPLASIA AFTER ENDOSCOPIC MUCOSAL RESECTION: COMPARISION OF HIGH DEFINITION WHITE LIGHT, NARROW BAND IMAGING AND NEAR FOCUS: FINAL ANALYSIS OF A PROSPECTIVE DOUBLE BLIND CLINICAL TRIAL

Author

Kandel, Pujan, primary, Brand, Eelco C., additional, Pelt, Joe, additional, Bouras, Ernest P., additional, Gomez, Victoria, additional, Raimondo, Massimo, additional, Woodward, Timothy A., additional, and Wallace, Michael B., additional more...

Published
2018
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50. 120 DIAGNOSTIC ACCURACY OF HIGH DEFINITION WHITE LIGHT, NARROW BAND IMAGING WITH OR WITHOUT NEAR FOCUS FOR ASSESSMENT OF COLORECTAL ENDOSCOPIC MUCOSAL RESECTION SCARS: ESCART TRIAL (EMR SCAR ASSESSMENT TRIAL), MULTICENTER IMAGE EVALUATION STUDY

Author

Kandel, Pujan, primary, Brand, Eelco C., additional, Pelt, Joe, additional, Raju, Gottumukkala S., additional, Rex, Douglas K., additional, Yang, Dennis, additional, Al-Haddad, Mohammad A., additional, Draganov, Peter, additional, Gill, Jeffrey, additional, Hassan, Cesare, additional, Grimm, Ian S., additional, Gordon, Stuart R., additional, Elmunzer, B. Joseph, additional, Dekker, Evelien, additional, Fockens, Paul, additional, Kahi, Charles J., additional, Levenick, John M., additional, Repici, Alessandro, additional, Tytgat, Kristien, additional, van der Vlugt, Manon, additional, Crockett, Seth, additional, Roberta, Marselli, additional, Tutticci, Nicholas J., additional, Kheir, Ammar O., additional, Rastogi, Amit, additional, Bansal, Ajay, additional, Ross, William A., additional, Burgess, Nicholas G., additional, Bourke, Michael J., additional, and Wallace, Michael B., additional more...

Published
2018
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