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5. T.07.10 PERFORMANCE OF A MULTI-COMPOUNDS NUTRACEUTICAL FORMULATION IN PATIENTS WITH SYMPTOMATIC UNCOMPLICATED DIVERTICULAR DISEASE

Author

Gravina, A.G., primary, Brandimarte, G., additional, Frajese, G.V., additional, Bargiggia, S., additional, Castellani, D., additional, Cocco, A., additional, Colucci, R., additional, Evangelista, E., additional, Napoletano, D., additional, Nardi, E., additional, Maisto, T., additional, Morabito, A., additional, Pianese, G., additional, Romano, A., additional, Sacco, R., additional, Sinnona, N., additional, Sediari, L., additional, Tifi, L., additional, Davino, A., additional, Elisei, W., additional, and Tursi, A., additional

Published
2022
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7. The DICA Endoscopic Classification for Diverticular Disease of the Colon Shows a Significant Interobserver Agreement among Community Endoscopists: an International Study

Author

Tursi A., Brandimarte G., Di Mario F., Lanas A., Scarpignato C., Bafutto M., Barbara G., Bassotti G., Binda G. A., Biondi A., Biondo S., Cassieri C., Crucitti A., Dumitrascu D. L., Elisei W., Escalante R., Herszenyi L., Kruis W., Kupcinskas J., Lahat A., Lecca P. G., Maconi G., Malfertheiner P., Mazzarri A., Mearin F., Milosavljevic T., Nardone G., de Oliveira E. C., Papa A., Papagrigoriadis S., Pera M., Persiani R., Picchio M., Regula J., Stimac D., Stollman N., Strate L. L., Walker M. M. D., Allegretta L., Altavilla N., Amaro P., Annunziata M. L., Barberio F., Basile G., Bedogni G., Belfiori V., Benvenuti S., Bertolami C., Bisello M., El Dammak M. B., Bozzi R., Buono M., Cambie G., Capezzuto E., Casamassima C., Chavoushian A., Ciofani R., Citarella C., Compare D., Cotruta B., D'amico F., Dulk M. D., Dyrda B. E., Festa V., Gallina S., Grasso R., Hanzel J., Taieb J. M., Lai M. A., Latella G., Lisi D., Lodi L., Marangi S., Mardegan A., Marlicz W., Maurano A., Milazzo G., Militaru V., Miraglia S., Monica F., Moskalev A., Natale A., Nicolas C., Pancetti A., Penna A., Pepe A. S., Pisano M., Pontone S., Prati M., Prisco A., Rando L., Hernandez E. R., Rosati O., Rossi G., Passoni G. R., Papa V., Nesme N. S., Schiffino L., Schillaci D., Selvaggi G., Taborchi F., Tornar A., Trebuna F., Triggiani C., Testai F. V., Vassallo R., Violi A., Tursi, A., Brandimarte, G., Di Mario, F., Lanas, A., Scarpignato, C., Bafutto, M., Barbara, G., Bassotti, G., Binda, G. A., Biondi, A., Biondo, S., Cassieri, C., Crucitti, A., Dumitrascu, D. L., Elisei, W., Escalante, R., Herszenyi, L., Kruis, W., Kupcinskas, J., Lahat, A., Lecca, P. G., Maconi, G., Malfertheiner, P., Mazzarri, A., Mearin, F., Milosavljevic, T., Nardone, G., de Oliveira, E. C., Papa, A., Papagrigoriadis, S., Pera, M., Persiani, R., Picchio, M., Regula, J., Stimac, D., Stollman, N., Strate, L. L., Walker, M. M. D., Allegretta, L., Altavilla, N., Amaro, P., Annunziata, M. L., Barberio, F., Basile, G., Bedogni, G., Belfiori, V., Benvenuti, S., Bertolami, C., Bisello, M., El Dammak, M. B., Bozzi, R., Buono, M., Cambie, G., Capezzuto, E., Casamassima, C., Chavoushian, A., Ciofani, R., Citarella, C., Compare, D., Cotruta, B., D'Amico, F., Dulk, M. D., Dyrda, B. E., Festa, V., Gallina, S., Grasso, R., Hanzel, J., Taieb, J. M., Lai, M. A., Latella, G., Lisi, D., Lodi, L., Marangi, S., Mardegan, A., Marlicz, W., Maurano, A., Milazzo, G., Militaru, V., Miraglia, S., Monica, F., Moskalev, A., Natale, A., Nicolas, C., Pancetti, A., Penna, A., Pepe, A. S., Pisano, M., Pontone, S., Prati, M., Prisco, A., Rando, L., Hernandez, E. R., Rosati, O., Rossi, G., Passoni, G. R., Papa, V., Nesme, N. S., Schiffino, L., Schillaci, D., Selvaggi, G., Taborchi, F., Tornar, A., Trebuna, F., Triggiani, C., Testai, F. V., Vassallo, R., Violi, A., Tursi A., Brandimarte G., Di Mario F., Lanas A., Scarpignato C., Bafutto M., Barbara G., Bassotti G., Binda G.A., Biondi A., Biondo S., Cassieri C., Crucitti A., Dumitrascu D.L., Elisei W., Escalante R., Herszenyi L., Kruis W., Kupcinskas J., Lahat A., Lecca P.G., Maconi G., Malfertheiner P., Mazzari A., Mearin F., Milosavljevic T., Nardone G., Chavez De Oliveira E., Papa A., Papagrigoriadis S., Pera M., Persiani R., Picchio M., Regula J., Stimac D., Stollman N., Strate L.L., and Walker M.M.

Subjects
BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences, Diverticular Disease, Endoscopic classification, Video Recording, Colonoscopy, Gastroenterology, Severity of Illness Index, endoscopic classification, Diverticulum, classification, complications, Diverticular diseases, Endoscopy, methods, Colonic Diseases, 0302 clinical medicine, Community Health Services, Community Health Service, Observer Variation, 0303 health sciences, medicine.diagnostic_test, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti, agreement − colonoscopy − community setting − diverticular disease of the colon− endoscopic classification, 3. Good health, Diverticulosis, Malalties del còlon, Diverticular disease of the colon, Diverticular disease, 616.344-007.64 [udc], Community setting, 030211 gastroenterology & hepatology, Human, medicine.medical_specialty, Scoring system, Colonic Disease, Settore MED/12 - GASTROENTEROLOGIA, Reproducibility of Result, agreement, colonoscopy, community setting, diverticular disease of the colon, Agreement, 03 medical and health sciences, Internal medicine, Severity of illness, medicine, Diverticulosis, Colonic, Humans, Colonic diseases, 030304 developmental biology, Diverticular Diseases, business.industry, Colonoscòpia, Reproducibility of Results, medicine.disease, Inter-rater reliability, business, Kappa
Abstract

Background and Aims: The Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification of diverticulosis and diverticular disease (DD) is currently available. It scores severity of the disease as DICA 1, DICA 2 and DICA 3. Our aim was to assess the agreement on this classification in an international endoscopists community setting. Methods: A total of 96 doctors (82.9% endoscopists) independently scored a set of DD endoscopic videos. The percentages of overall agreement on DICA score and a free-marginal multirater kappa (κ) coefficient were reported as statistical measures of interrater agreement. Results: Overall agreement in using DICA was 91.8% with a free-marginal kappa of 88% (95% CI 80-95). The overall agreement levels were: DICA 1, 85.2%; DICA 2, 96.5%; DICA 3, 99.5%. The free marginal κ was: DICA 1 = 0.753, DICA 2 = 0.958, DICA 3 = 0.919. The agreement about the main endoscopic items was 83.4% (k 67%) for diverticular extension, 62.6% (k 65%) for number of diverticula for each district, 86.8% (k 82%) for presence of inflammation, and 98.5 (k 98%) for presence of complications. Conclusions: The overall interrater agreement in this study ranges from good to very good. DICA score is a simple and reproducible endoscopic scoring system for diverticulosis and DD.

Published
2019

11. Predictive value of the “DICA” classification on the outcome of diverticular disease of the colon: an international study: 3.14

Author

Tursi, A., Brandimarte, G., Di Mario, F., Annunziata, M. L., Bafutto, M., Bianco, M. A., Colucci, R., Conigliaro, R., Danese, S., De Bastiani, R., Elisei, W., Escalante, R., Faggiani, R., Ferrini, L., Forti, G., Latella, G., Graziani, M. G., Oliveira, E., Papa, A., Penna, A., Søreide, K., Spadaccini, A., Usai, P., Zampaletta, C., Cassieri, C., Desserud, K. F., Fiorella, S., Landi, R., Goni, E., Lai, M. A., Pigò, F., Scarpignato, C., Picchio, M., Scaccianoce, G., and Portincasa, P.

Published
2016

12. Predictive value of the ‘DICA’ classification on the outcome of diverticular disease of the colon: 2.14

Author

Tursi, A., Brandimarte, G., Di Mario, F., Annunziata, M. L., Bianco, M. A., Conigliaro, R., Elisei, W., Faggiani, R., Forti, G., Lecca, P. G., Penna, A., Spadaccini, A., Zampaletta, C., Colucci, R., De Bastiani, R., Di Cesare, L., Di Fonzo, M., Goni, E., Ferrini, L., Graziani, M. G., Latella, G., Pigò, F., Rotondano, G., Schiaccianoce, G., Picchio, M., Scarpignato, C., and Portincasa, P.

Published
2015

17. Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease – a double-blind, randomised, placebo-controlled study

Author

Tursi, A., Brandimarte, G., Elisei, W., Picchio, M., Forti, G., Pianese, G., Rodino, S., DʼAmico, T., Sacca, N., Portincasa, P., Capezzuto, E., Lattanzio, R., Spadaccini, A., Fiorella, S., Polimeni, F., Polimeni, N., Stoppino, V., Stoppino, G., Giorgetti, G. M., Aiello, F., and Danese, S.

Published
2013
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19. T01.01.14 THE ROLE OF A NON-INVASIVE TEST IN THE MANAGEMENT OF UPPER-GI DISEASES: COMPARISON BETWEEN SEROLOGY AND ENDOSCOPIC FINDINGS IN A SAMPLE OF 3,795 PATIENTS

Author

Barchi, A., primary, Franceschi, M., additional, Russo, M., additional, Miraglia, C., additional, Crafa, P., additional, Franzoni, L., additional, Ferronato, A., additional, Rodriguez-Castro, K., additional, Baldassarre, G., additional, Panozzo, M.P., additional, Antico, A., additional, Rugge, M., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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20. OC.08.3 THE “DICA” ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE OF THE COLON SHOWS A SIGNIFICANT INTEROBSERVER AGREEMENT AMONG COMMUNITY ENDOSCOPISTS: AN INTERNATIONAL STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Lanas, A., additional, Scarpignato, C., additional, Bafutto, M., additional, Barbara, G., additional, Bassotti, G., additional, Binda, G.A., additional, Biondi, A., additional, Biondo, S., additional, Cambiè, G., additional, Cassieri, C., additional, Crucitti, A., additional, Dumitrascu, D., additional, Elisei, W., additional, Escalante, R., additional, Herszènyi, L., additional, Kruis, W., additional, Kupcinskas, J., additional, Lahat, A., additional, Lecca, P.G., additional, Maconi, G., additional, Malfertheiner, P., additional, Mazzari, A., additional, Mearìn, F., additional, Milosavljevic, T., additional, Nardone, G., additional, Chavez De Oliveira, E., additional, Papa, A., additional, Papagrigoriadis, S., additional, Pera, M., additional, Persiani, R., additional, Picchio, M., additional, Regula, J., additional, Štimac, D., additional, Stollman, N., additional, Strate, L., additional, Violi, A., additional, and Walker, M., additional

Published
2020
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21. T04.01.12 USEFULNESS OF FECAL CALPROTECTIN IN PRIMARY CARE SETTING: AN EXPERIENCE IN NORTH – EAST ITALY POPULATION

Author

Moccia, F., primary, Ferronato, A., additional, Barchi, A., additional, Miraglia, C., additional, Russo, M., additional, Franceschi, M., additional, Rodriguez-Castro, K., additional, Baldassarre, G., additional, Franzoni, L., additional, Crafa, P., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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24. T01.02.17 CLINICAL USEFULNESS OF SECOND-GENERATION BARRIER DRUGS IN GERD PATIENTS WITH ATYPICAL SYMPTOMS: A-6-MONTHS PROSPECTIVE STUDY

Author

Barchi, A., primary, Russo, M., additional, Miraglia, C., additional, Franzoni, L., additional, Crafa, P., additional, Franceschi, M., additional, Baldassarre, G., additional, Rodriguez-Castro, K., additional, Tursi, A., additional, Brandimarte, G., additional, Savarino, E., additional, De Bortoli, N., additional, and Di Mario, F., additional

Published
2020
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25. T01.02.23 ROLE OF ENVIRONMENTAL FACTORS ON THE OUTCOME OF GASTROESOPHAGEAL REFLUX DISEASE: 6 MONTHS PROSPECTIVE STUDY

Author

Russo, M., primary, Barchi, A., additional, Miraglia, C., additional, Franzoni, L., additional, Crafa, P., additional, Franceschi, M., additional, Baldassarre, G., additional, Rodriguez-Castro, K., additional, Tursi, A., additional, Brandimarte, G., additional, Savarino, E., additional, De Bortoli, N., additional, and Di Mario, F., additional

Published
2020
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27. OC.08.6 USEFULNESS OF FECAL CALPROTECTIN IN PRIMARY CARE: NON-INVASIVE APPROACH FOR THE FRAMING OF INTESTINAL DISEASES

Author

Moccia, F., primary, Ferronato, A., additional, Franceschi, M., additional, Baldassarre, G., additional, Panozzo, M.P., additional, Antico, A., additional, Barchi, A., additional, Russo, M., additional, Miraglia, C., additional, Franzoni, L., additional, Crafa, P., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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29. T01.01.16 CORRELATION BETWEEN SERUM GASTRIC BIOMARKERS AND HISTOLOGICAL PICTURES OF H. PYLORI INFECTION AND ATROPHIC GASTRITIS: A POPULATION STUDY ON 1,122 PATIENTS

Author

Barchi, A., primary, Franceschi, M., additional, Russo, M., additional, Miraglia, C., additional, Crafa, P., additional, Franzoni, L., additional, Ferronato, A., additional, Rodriguez-Castro, K., additional, Baldassarre, G., additional, Panozzo, M.P., additional, Antico, A., additional, Rugge, M., additional, Tursi, A., additional, Brandimarte, G., additional, and Di Mario, F., additional

Published
2020
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41. P.02.12 PREDICTIVE VALUE OF THE “DICA” ENDOSCOPIC CLASSIFICATION ON THE OUTCOME OF DIVERTICULAR DISEASE OF THE COLON: A 1-YEAR ANALYSIS FROM THE INTERNATIONAL, MULTICENTER, PROSPECTIVE STUDY

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Elisei, W., additional, Picchio, M., additional, Allegretta, L., additional, Annunziata, M.L., additional, Astegiano, M., additional, Bafutto, M., additional, Baldi, F., additional, Bassotti, G., additional, Bianco, M.A., additional, Colucci, R., additional, Conigliaro, R., additional, Danese, S., additional, Dumitrascu, D.L., additional, Escalante, R., additional, Faggiani, R., additional, Fiorella, S., additional, Forti, G., additional, Franceschi, M., additional, Giorgetti, G., additional, Grad, S., additional, Graziani, M.G., additional, Lai, M.A., additional, Lammert, F., additional, Latella, G., additional, Lisi, D., additional, Maconi, G., additional, Murphy, M.M., additional, Nardone, G., additional, De Oliveira, L. Camara, additional, De Oliveira, E. Chaves, additional, Papa, A., additional, Papagrigoriadis, S., additional, Penna, A., additional, Pietrzak, A., additional, Pontone, S., additional, Portincasa, P., additional, Poskus, T., additional, Pranzo, G., additional, Reichert, M., additional, Rizzo, G.L., additional, Rodinò, S., additional, Regula, J., additional, Scaccianoce, G., additional, Scaldaferri, F., additional, Schiffino, L., additional, Stundiene, I., additional, Vassallo, R., additional, Walker, M., additional, Zampaletta, C., additional, and Zullo, A., additional

Published
2019
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45. OC.05.6 THE PROGNOSTIC VALUE OF A NEW ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE: DICA (DIVERTICULAR INFLAMMATION AND COMPLICATION ASSESSMENT)

Author

Cambiè, G., primary, Violi, A., additional, Tursi, A., additional, Brandimarte, G., additional, Franceschi, M., additional, Franzoni, L., additional, Rodriguez-Castro, K.I., additional, Miraglia, C., additional, Baldassarre, G., additional, Nouvenne, A., additional, Crafa, P., additional, and Di Mario, F., additional

Published
2019
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46. OC.03.3 THE “DICA” ENDOSCOPIC CLASSIFICATION FOR DIVERTICULAR DISEASE OF THE COLON SHOWS A SIGNIFICANT INTEROBSERVER AGREEMENT AMONG COMMUNITY ENDOSCOPISTS

Author

Tursi, A., primary, Brandimarte, G., additional, Di Mario, F., additional, Nardone, G., additional, Scarpignato, C., additional, Picchio, M., additional, Elisei, W., additional, Allegretta, L., additional, Annunziata, M.L., additional, Astegiano, M., additional, Baldi, F., additional, Bassotti, G., additional, Bianco, M.A., additional, Cambiè, G., additional, Capezzuto, E., additional, Caroli, A., additional, Cassieri, C., additional, Cicu, A.S., additional, Ciliberto, E., additional, Colucci, R., additional, Conigliaro, R., additional, Damiani, A., additional, De Colibus, P., additional, De Medici, A., additional, De Pretis, G., additional, Favero, G. Del, additional, Valle, N. Della, additional, Di Cesare, L., additional, Faggiani, R., additional, Febbraro, S., additional, Ferrini, L., additional, Fiorella, S., additional, Forti, G., additional, Franceschi, M., additional, Frunzio, A., additional, Germanà, B., additional, Giorgetti, G., additional, Giovannone, M., additional, Graziani, M.G., additional, Lai, M.A., additional, Latella, G., additional, Lisi, D., additional, Lopetuso, L.R., additional, Maconi, G., additional, Mandelli, E.D., additional, Marmo, R., additional, Maurano, A., additional, Pallotta, L., additional, Papa, A., additional, Parmeggiani, F., additional, Penna, A., additional, Pigò, F., additional, Pontone, S., additional, Pranzo, G., additional, Ricciardelli, C., additional, Rizzo, G.L., additional, Rodinò, S., additional, Savarino, E., additional, Scaccianoce, G., additional, Scaldaferri, F., additional, Schiffino, L., additional, Semeraro, C., additional, Stroppa, I., additional, Urgesi, R., additional, Vassallo, R., additional, Violi, A., additional, Zampaletta, C., additional, Lecca, P.G., additional, Zilli, M., additional, and Zullo, A., additional

Published
2019
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48. Effectiveness and Safety of Pylera® in Patients Infected by Helicobacter Pylori: A Multicenter, Retrospective, Real Life Study

Author

Tursi, A., Franceschi, M., Allegretta, L., Savarino, E., De Bastiani, R., Elisei, W., Baldassarre, G., Ferronato, A., Scida, S., Miraglia, C., Penna, A., Licci, C., Rizzo, G. L., Pranzo, G., Cassieri, C., Brandimarte, G., Picchio, M., and Di Mario, F.

Subjects
Male, Helicobacter pylori, Antibiotics, Bismuth-containing therapy, Safety, Treatment, Anti-Bacterial Agents, Bismuth, Demography, Drug Therapy, Combination, Endoscopy, Female, Helicobacter Infections, Humans, Metronidazole, Middle Aged, Organometallic Compounds, Retrospective Studies, Tetracycline, Treatment Outcome, Drug Therapy, Combination
Abstract

Our aims were to assess the real life effectiveness and safety of the new bismuth-containing quadruple therapy in a large population of patients infected by Helicobacter pylori.Consecutive dyspeptic H. pylori-positive patients were enrolled, both naïve for treatment and already unsuccessfully treated. Patients were treated with Pylera® 3 capsules 4 times/daily plus omeprazole 20 mg or esomeprazole 40 mg 2 times/daily for 10 days. Eradication was confirmed using a urea-breath test (at least 30 days after the end of the treatment). Efficacy and safety were assessed.A total of 349 patients were treated. H. pylori eradication was achieved in 316 (90.5%, 95% CIs 80.8-1.0) patients in the intention-to-treat population, and in 93.5% (95% CIs 83.5-1.0) in the per-protocol population. No difference in the eradication rate was found between naïve and previously treated patients (91.3 vs. 90.0%, p = 0.901). Adverse events occurred in 55 patients (15.8%, 95% CIs 11.9-20.1). Five patients discontinued treatment: 2 patients suffered from severe abdominal pain, one patient from headache, one patient from diarrhea, and one patient from diffuse urticarial rush.Pylera® achieved a remarkable eradication rate in real life both as first treatment and as a rescue therapy, with a good safety profile.

Published
2017

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