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425 results on '"Briedis, Vitalis"'

1. In Vitro Study of Cyano-Phycocyanin Release from Hydrogels and Ex Vivo Study of Skin Penetration.

Author

Galinytė, Daiva, Bernatoniene, Jurga, Žilius, Modestas, Rysevaitė-Kyguolienė, Kristina, Savickas, Arūnas, Karosienė, Jūratė, Briedis, Vitalis, Pauža, Dainius Haroldas, and Savickienė, Nijolė

Subjects
PROPYLENE glycols, LASER microscopy, BIOPOLYMERS, HYDROGELS, IN vitro studies
Abstract

Background: This study explored the most suitable materials for incorporating cyano-phycocyanin (C-PC) into hydrogels, focusing on maintaining the C-PC's long-term structural integrity and stabilityNext, the release of C-PC from the hydrogels and its skin penetration were investigated. Methods: A series of 1% (w/w) C-PC hydrogels was prepared using various gelling agents and preservatives. Spectrophotometric measurements compared the amount of C-PC in the hydrogels to the initially added amount. After selecting the most suitable gelling agent and preservative, two C-PC hydrogels, with and without propylene glycol (PG) (Sigma-Aldrich, St. Louis, MO, USA), were produced for further testing. In vitro release studies utilized modified Franz-type diffusion cells, while ex vivo skin-permeation studies employed Bronaugh-type cells and human skin. Confocal laser scanning microscopy analyzed C-PC accumulation in the skin. Results: The findings demonstrated that sodium alginate (Sigma-Aldrich, St. Louis, MO, USA), hydroxyethyl cellulose (HEC) (Sigma-Aldrich, St. Louis, MO, USA), and SoligelTM (Givaudan, Vernier, Switzerland) are effective biopolymers for formulating hydrogels while maintaining C-PC stability. After 6 h, C-PC release from the hydrogel containing PG was approximately 10% or 728.07 (±19.35) μg/cm2, significantly higher than the nearly 7% or 531.44 (±26.81) μg/cm2 release from the hydrogel without PG (p < 0.05). The ex vivo qualitative skin-permeation study indicated that PG enhances C-PC penetration into the outermost skin layer. Conclusion: PG's ability to enhance the release of C-PC from the hydrogel, coupled with its capacity to modify the skin barrier ex vivo, facilitates the penetration of C-PC into the stratum corneum. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Clinical aspects of reimbursement policies for orphan drugs in Central and Eastern European countries

Author

Jakubowski, Szczepan, primary, Kawalec, Pawel, additional, Holko, Przemyslaw, additional, Kowalska-Bobko, Iwona, additional, Kamusheva, Maria, additional, Petrova, Guenka, additional, Draganić, Pero, additional, Fuksa, Leos, additional, Männik, Agnes, additional, Ispán, Fanni, additional, Briedis, Vitalis, additional, Bianchi, Ioana, additional, Paveliu, Marian Sorin, additional, and Tesar, Tomas, additional

Published
2024
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4. Topical antifungal bigels: Formulation, characterization and evaluation

Author

Mazurkeviciute Agne, Ramanauskiene Kristina, Ivaskiene Marija, Grigonis Aidas, and Briedis Vitalis

Subjects
bigel, ciclopirox olamine, terbinafine hydrochloride, poloxamer 407, antifungal, microsporum canis, Pharmaceutical industry, HD9665-9675
Abstract

Bigels with antifungal substances, ciclopirox olamine and terbinafine hydrochloride, were made of hydrogel (poloxamer 407 gel) and oleogel (polyethylene and liquid paraffin mixture). Prepared bigels were found physically stable at room temperature for six months and at least four months at 40 °C. Released amount of drug decreased when oleogel concentration in the formulation increased. Release test results depended on the insertion place of active substances. The amount of released substance was highest when ciclopirox olamine was incorporated in both phases in an equal quantity, and terbinafine hydrochloride in oleogel or in hydrogel. All formulations showed great inhibition of Microsporum canis. Thus, bigels with ciclopirox olamine and terbinafine hydrochloride are a promising dosage form for topical use.

Published
2018
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6. Testing of resveratrol microemulsion photostability and protective effect against UV induced oxidative stress

Author

Juškaitė Vaida, Ramanauskienė Kristina, and Briedis Vitalis

Subjects
microemulsion, resveratrol, photostability, ha-cat cells, uvb, oxidative stress, Pharmaceutical industry, HD9665-9675
Abstract

Resveratrol is well known for its antioxidant activity and susceptibility to ultraviolet radiation. Development of formulations providing improved stability and relevant drug delivery of resveratrol is still a challenging task. The aim of this study was to determine protective characteristics of formulated microemulsions by evaluating photoisomerization of resveratrol and to investigate the effects of resveratrol on human keratinocyte cells under oxidative stress caused by ultraviolet radiation. Incorporation of resveratrol into microemulsions resulted in increased photostability of active compounds and the results demonstrated that photodegradation of resveratrol was significantly delayed. Results of biopharmaceutical evaluation in vitro demonstrated that up to 60 % of resveratrol was released from microemulsions within 6 hours under a constant release rate profile. In vivo biological testing confirmed the ability of resveratrol to protect cells from oxidative stress and to increase cell viability. It was concluded that microemulsions might be considered in the development of UV light sensitive compounds.

Published
2017
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7. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

Author

Bousquet, J. Jean, Schünemann, Holger J., Togias, Alkis, Erhola, Marina, Hellings, Peter W., Zuberbier, Torsten, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bachert, Claus, Becker, Sven, Bedolla-Barajas, Martin, Bewick, Michael, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Boulet, Louis P., Bourrez, Jean Marc, Brusselle, Guy, Chavannes, Niels, Costa, Elisio, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Fokkens, Wytske J., Fonseca, Joao A., Gaga, Mina, Haahtela, Tari, Illario, Maddalena, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T. T., Larenas-Linnemann, Desiree, Laune, Daniel, Lourenço, Olga M., Menditto, Enrica, Mullol, Joaquin, Okamoto, Yashitaka, Papadopoulos, Nikos, Pham-Thi, Nhân, Picard, Robert, Pinnock, Hilary, Roche, Nicolas, Roller-Wirnsberger, Regina E., Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Vasankari, Tuula, Ventura, Maria-Teresa, Walker, Samantha, Williams, Sian, Akdis, Cezmi A., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, Bateman, Eric, Bedbrook, Anna, Bennoor, K. S., Benveniste, Samuel, Bergmann, Karl C., Bialek, Slawomir, Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Mateo, Bonniaud, Philippe, Bouchard, Jacques, Briedis, Vitalis, Brightling, Christofer E., Brozek, Jan, Buhl, Roland, Buonaiuto, Roland, Canonica, Giorgo W., Cardona, Victoria, Carriazo, Ana M., Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., Chkhartishvili, Eka, Chu, Derek K., Cingi, Cemal, Colgan, Elaine, de Sousa, Jaime Correia, Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, D’Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejand, Dauvilliers, Yves, Dedeu, Antoni, De Feo, Giulia, Devillier, Philippe, Di Capua, Stefania, Dykewickz, Marc, Dubakiene, Ruta, Ebisawa, Motohiro, El-Gamal, Yaya, Eller, Esben, Emuzyte, Regina, Farrell, John, Fink-Wagner, Antjie, Fiocchi, Alessandro, Fontaine, Jean F., Gemicioğlu, Bilun, Schmid-Grendelmeir, Peter, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gomez, Maximiliano, González Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria-Antonieta, Hajjam, Jawad, O’B Hourihane, John, Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Illario, Maddalena, Ivancevich, Juan C., Joos, Guy, Jung, Ki-Suck, Jutel, Marek, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Mussa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, Leonardini, Lisa, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Marien, Gert, Mahboub, Bassam, Malva, Joao, Manning, Patrick, De Manuel Keenoy, Esteban, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Mathieu-Dupas, Eve, Matricardi, Poalo M., Melén, Eric, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Moda, Giuliana, Mogica-Martinez, Maria-Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralf, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leila, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Novellino, Enrico, Nyembue, Dieudonné, O’Hehir, Robin, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle, Ouedraogo, Solange, Pali-Schöll, Isabella, Palkonen, Susanna, Panzner, Peter, Park, Hae-Sim, Pépin, Jean-Louis, Pereira, Ana-Maria, Pfaar, Oliver, Paulino, Ema, Phillips, Jim, Picard, Robert, Plavec, Davor, Popov, Ted A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Pugin, Benoit, Raciborski, Filip, Rajabian-Söderlund, Rojin, Reitsma, Sietze, Rodo, Xavier, Romano, Antonino, Rosario, Nelson, Rottem, Menahenm, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sisul, Juan-Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spranger, Otto, Stellato, Cristina, Stelmach, Rafael, Suppli Ulrik, Charlotte, Thibaudon, Michel, To, Teresa, Todo-Bom, Ana, Tomazic, Peter V., Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, van der Kleij, Rianne, Vandenplas, Olivier, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Y., Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yorgancioglu, Arzu, Yusuf, Osman M., Zar, Heahter J., Zeng, Stéphane, Zernotti, Mario, Zhang, Luo, Zhong, Nan S., Zidarn, Mihaela, the ARIA Study Group, and the MASK Study Group

Published
2019
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9. Release of rosmarinic acid from semisolid formulations and its penetration through human skin ex vivo

Author

Stelmakienė Ada, Ramanauskienė Kristina, and Briedis Vitalis

Subjects
human skin penetration, rosmarinic acid, rheology, release, Pharmaceutical industry, HD9665-9675
Abstract

The aim of this study was to evaluate the release of rosmarinic acid (RA) from the experimental topical formulations with the Melissa officinalis L. extract and to evaluate its penetration through undamaged human skin ex vivo. The results of the in vitro release study showed that higher amounts of RA were released from the emulsion vehicle when lemon balm extract was added in its dry form. An inverse correlation was detected between the released amount of RA and the consistency index of the formulation. Different penetration of RA into the skin may be influenced by the characteristics of the vehicle as well as by the form of the extract. The results of penetration assessment showed that the intensity of RA penetration was influenced by its lipophilic properties: RA was accumulating in the epidermis, while the dermis served as a barrier, impeding its deeper penetration.

Published
2015
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10. Management of allergic rhinitis symptoms in the pharmacy Pocket guide 2022

Author

Lourenço, Olga, Cvetkovski, Biljana, Kritikos, Vicky, House, Rachel, Scheire, Sophie, Costa, Elísio, Fonseca, Joao A, Menditto, Enrica, Bedbrook, Anna, Bialek, Slawomir, Briedis, Vitalis, Boussery, Koen, Canonica, G. Walter, Haahtela, Tari, Kuna, Piotr, Mullol, Joaquim, Orlando, Valentina, Samolinski, Boleslaw, Wallace, Dana, Duggan, Catherine, Paulino, Ema, Pinto, Gonçalo S., Söderlund, Lars‐Åke, Bousquet, Jean, Bosnic‐Anticevich, Sinthia, HUS Inflammation Center, Department of Dermatology, Allergology and Venereology, Helsinki University Hospital Area, Clinicum, University of Helsinki, uBibliorum, and Publica

Subjects
Pulmonary and Respiratory Medicine, allergic rhinitis, Allergy, IMPACT, pharmacist, Immunology, Biology and Life Sciences, QUALITY-OF-LIFE, 3121 General medicine, internal medicine and other clinical medicine, Medicine and Health Sciences, Immunology and Allergy, community pharmacy, ASTHMA, EPIDEMIOLOGY
Abstract

This research received no specific grant from any funding agency in the public, commercial, or not‐for‐profit sectors. Open access funding enabled and organized by Projekt DEAL, Background: Allergic rhinitis (AR) management requires a coordinated effort from healthcare providers and patients. Pharmacists are key members of these integrated care pathways resolving medication-related problems, optimizing regimens, improving adherence and recommending therapies while establishing liaisons between patients and physicians. Methods: Allergic Rhinitis and its Impact on Asthma (ARIA) first published a reference document on the pharmacist's role in allergic rhinitis management in 2004. Several guidelines were developed over the past 20 years improving the care of allergic rhinitis patients through an evidence-based, integrated care approach. Results: This ARIA/EAACI/FIP Position Paper is based on the latest ARIA in the Pharmacy guidelines and provides: (a) a structured approach to pharmacists identifying people with AR and/or allergic conjunctivitis as well as those at risk of poor disease control; (b) an evidence-based clinical decision support tool for optimising the management of allergic rhinitis in the community pharmacy; and (c) a framework of referral to the physician. Conclusion: This document is not intended to be a mandatory standard of care but is provided as a basis for pharmacists and their staff to develop relevant local standards of care for their patients, within their local practice environment. Pharmacy care varies between countries, and the guide should be adapted to the local situation.

Published
2022

14. ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice

Author

Bousquet, Jean Anto, Josep M. Bachert, Claus Haahtela, Tari and Zuberbier, Torsten Czarlewski, Wienczyslawa Bedbrook, Anna and Bosnic-Anticevich, Sinthia Walter Canonica, G. Cardona, Victoria Costa, Elisio Cruz, Alvaro A. Erhola, Marina and Fokkens, Wytske J. Fonseca, Joao A. Illario, Maddalena and Ivancevich, Juan-Carlos Jutel, Marek Klimek, Ludger Kuna, Piotr Kvedariene, Violeta Le, L. T. T. Larenas-Linnemann, Desiree E. Laune, Daniel Lourenco, Olga M. Melen, Erik and Mullol, Joaquim Niedoszytko, Marek Odemyr, Mikaela Okamoto, Yoshitaka Papadopoulos, Nikos G. Patella, Vincenzo Pfaar, Oliver Pham-Thi, Nhan Rolland, Christine Samolinski, Boleslaw Sheikh, Aziz Sofiev, Mikhail Suppli Ulrik, Charlotte Todo-Bom, Ana Tomazic, Peter-Valentin and Toppila-Salmi, Sanna Tsiligianni, Ioanna Valiulis, Arunas and Valovirta, Erkka Ventura, Maria-Teresa Walker, Samantha and Williams, Sian Yorgancioglu, Arzu Agache, Ioana Akdis, Cezmi A. Almeida, Rute Ansotegui, Ignacio J. Annesi-Maesano, Isabella Arnavielhe, Sylvie Basagana, Xavier D. Bateman, Eric Bedard, Annabelle Bedolla-Barajas, Martin Becker, Sven and Bennoor, Kazi S. Benveniste, Samuel Bergmann, Karl C. and Bewick, Michael Bialek, Slawomir E. Billo, Nils and Bindslev-Jensen, Carsten Bjermer, Leif Blain, Hubert Bonini, Matteo Bonniaud, Philippe Bosse, Isabelle Bouchard, Jacques and Boulet, Louis-Philippe Bourret, Rodolphe Boussery, Koen and Braido, Fluvio Briedis, Vitalis Briggs, Andrew Brightling, Christopher E. Brozek, Jan Brusselle, Guy Brussino, Luisa and Buhl, Roland Buonaiuto, Roland Calderon, Moises A. and Camargos, Paulo Camuzat, Thierry Caraballo, Luis Carriazo, Ana-Maria Carr, Warner Cartier, Christine Casale, Thomas and Cecchi, Lorenzo Cepeda Sarabia, Alfonso M. H. Chavannes, Niels and Chkhartishvili, Ekaterine Chu, Derek K. Cingi, Cemal and Correia de Sousa, Jaime Costa, David J. Courbis, Anne-Lise and Custovic, Adnan Cvetkosvki, Biljana D'Amato, Gennaro da Silva, Jane Dantas, Carina Dokic, Dejan Dauvilliers, Yves and De Feo, Giulia De Vries, Govert Devillier, Philippe Di Capua, Stefania Dray, Gerard Dubakiene, Ruta Durham, Stephen R. Dykewicz, Marc Ebisawa, Motohiro Gaga, Mina El-Gamal, Yehia Heffler, Enrico Emuzyte, Regina Farrell, John and Fauquert, Jean-Luc Fiocchi, Alessandro Fink-Wagner, Antje and Fontaine, Jean-Francois Fuentes Perez, Jose M. Gemicioglu, Bilun and Gamkrelidze, Amiran Garcia-Aymerich, Judith Gevaert, Philippe Gomez, Rene Maximiliano Gonzalez Diaz, Sandra and Gotua, Maia Guldemond, Nick A. Guzman, Maria-Antonieta and Hajjam, Jawad Huerta Villalobos, Yunuen R. Humbert, Marc and Iaccarino, Guido Ierodiakonou, Despo Iinuma, Tomohisa and Jassem, Ewa Joos, Guy Jung, Ki-Suck Kaidashev, Igor and Kalayci, Omer Kardas, Przemyslaw Keil, Thomas Khaitov, Musa and Khaltaev, Nikolai Kleine-Tebbe, Jorg Kouznetsov, Rostislav and Kowalski, Marek L. Kritikos, Vicky Kull, Inger La Grutta, Stefania Leonardini, Lisa Ljungberg, Henrik and Lieberman, Philip Lipworth, Brian Lodrup Carlsen, Karin C. and Lopes-Pereira, Catarina Loureiro, Claudia C. Louis, Renaud and Mair, Alpana Mahboub, Bassam Makris, Michael Malva, Joao and Manning, Patrick Marshall, Gailen D. Masjedi, Mohamed R. and Maspero, Jorge F. Carreiro-Martins, Pedro Makela, Mika and Mathieu-Dupas, Eve Maurer, Marcus De Manuel Keenoy, Esteban and Melo-Gomes, Elisabete Meltzer, Eli O. Menditto, Enrica and Mercier, Jacques Micheli, Yann Miculinic, Neven Mihaltan, Florin Milenkovic, Branislava Mitsias, Dimitirios I. Moda, Giuliana Mogica-Martinez, Maria-Dolores Mohammad, Yousser and Montefort, Steve Monti, Ricardo Morais-Almeida, Mario and Mosges, Ralph Munter, Lars Muraro, Antonella Murray, Ruth and Naclerio, Robert Napoli, Luigi Namazova-Baranova, Leyla and Neffen, Hugo Nekam, Kristoff Neou, Angelo Nordlund, Bjorn and Novellino, Ettore Nyembue, Dieudonne O'Hehir, Robyn and Ohta, Ken Okubo, Kimi Onorato, Gabrielle L. Orlando, Valentina Ouedraogo, Solange Palamarchuk, Julia Pali-Scholl, Isabella Panzner, Peter Park, Hae-Sim Passalacqua, Gianni and Pepin, Jean-Louis Paulino, Ema Pawankar, Ruby Phillips, Jim Picard, Robert Pinnock, Hilary Plavec, Davor Popov, Todor A. Portejoie, Fabienne Price, David Prokopakis, Emmanuel P. Psarros, Fotis Pugin, Benoit Puggioni, Francesca and Quinones-Delgado, Pablo Raciborski, Filip and Rajabian-Soderlund, Rojin Regateiro, Frederico S. Reitsma, Sietze Rivero-Yeverino, Daniela Roberts, Graham Roche, Nicolas Rodriguez-Zagal, Erendira Rolland, Christine and Roller-Wirnsberger, Regina E. Rosario, Nelson Romano, Antonino and Rottem, Menachem Ryan, Dermot Salimaki, Johanna and Sanchez-Borges, Mario M. Sastre, Joaquin Scadding, Glenis K. and Scheire, Sophie Schmid-Grendelmeier, Peter Schunemann, Holger J. and Sarquis Serpa, Faradiba Shamji, Mohamed Sisul, Juan-Carlos and Sofiev, Mikhail Sole, Dirceu Somekh, David Sooronbaev, Talant Sova, Milan Spertini Spranger, Otto Stellato, Cristiana Stelmach, Rafael Thibaudon, Michel To, Teresa and Toumi, Mondher Usmani, Omar Valero, Antonio A. Valenta, Rudolph Valentin-Rostan, Marylin Pereira, Marilyn Urrutia and van der Kleij, Rianne Van Eerd, Michiel Vandenplas, Olivier and Vasankari, Tuula Vaz Carneiro, Antonio Vezzani, Giorgio and Viart, Frederic Viegi, Giovanni Wallace, Dana Wagenmann, Martin Wang, De Yun Waserman, Susan Wickman, Magnus and Williams, Dennis M. Wong, Gary Wroczynski, Piotr Yiallouros, Panayiotis K. Yusuf, Osman M. Zar, Heather J. Zeng, Stephane and Zernotti, Mario E. Zhang, Luo Shan Zhong, Nan Zidarn, Mihaela

Abstract

Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.

Published
2021

15. Digital transformation of health and care in airway diseases from research to practice

Author

Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T.T., Larenas-Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga M., Melén, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaëla, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhân, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagaña, Xavier, D. Bateman, Eric, Bédard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean François, Fuentes Perez, José M., Gemicioğlu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, René Maximiliano, González Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michaël, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralph, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Björn, Novellino, Ettore, Nyembue, Dieudonné, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Schöll, Isabella, Panzner, Peter, Park, Hae Sim, Passalacqua, Gianni, Pépin, Jean Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Söderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schünemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, François, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stéphane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, Zidarn, Mihaela, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Subjects
ARIA, rhinitis, CARAT, MASK, Immunology, Immunology and Allergy, asthma, digital transformation of health and care
Abstract

Funding: MA reports personal fees from POCI-01-0145-FEDER-029130 mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases—generalization and evaluation of gamification, peer support and advanced image processing technologies from ERDF (European Regional Development Fund) funded by the COMPETE2020 and by National Funds through FCT (Fundação para a Ciência e a Tecnologia)… Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed. publishersversion published

Published
2021

16. ARIA digital anamorphosis : Digital transformation of health and care in airway diseases from research to practice

Author

Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan-Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T. T., Larenas-Linnemann, Desiree E., Laune, Daniel, Lourenco, Olga M., Melen, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhan, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter-Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria-Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, D. Bateman, Eric, Bedard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis-Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana-Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne-Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean-Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean-Francois, Fuentes Perez, Jose M., Gemicioglu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, Rene Maximiliano, Gonzalez Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzman, Maria-Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki-Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michael, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria-Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mosges, Ralph, Munter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Bjorn, Novellino, Ettore, Nyembue, Dieudonne, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Scholl, Isabella, Panzner, Peter, Park, Hae-Sim, Passalacqua, Gianni, Pepin, Jean-Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Soderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimaki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schunemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan-Carlos, Sole, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frederic, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stephane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, Zidarn, Mihaela, Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan-Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T. T., Larenas-Linnemann, Desiree E., Laune, Daniel, Lourenco, Olga M., Melen, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaela, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhan, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter-Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria-Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, D. Bateman, Eric, Bedard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis-Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana-Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne-Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean-Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean-Francois, Fuentes Perez, Jose M., Gemicioglu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, Rene Maximiliano, Gonzalez Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzman, Maria-Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki-Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michael, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria-Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mosges, Ralph, Munter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Bjorn, Novellino, Ettore, Nyembue, Dieudonne, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Scholl, Isabella, Panzner, Peter, Park, Hae-Sim, Passalacqua, Gianni, Pepin, Jean-Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Soderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimaki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schunemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan-Carlos, Sole, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frederic, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stephane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, and Zidarn, Mihaela

Abstract

Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.

Published
2021
Full Text
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17. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases: Review

Author

Schünemann, Holger J., Yiallouros, Panayiotis K., Bousquet, J. Jean, Togias, Alkis, Erhola, Marina, Hellings, Peter W., Zuberbier, Torsten, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bachert, Claus, Becker, Sven, Bedolla-Barajas, Martin, Bewick, Michael, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Boulet, Louis P., Bourrez, Jean Marc, Brusselle, Guy, Chavannes, Niels, Costa, Elisio, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Fokkens, Wytske J., Fonseca, Joao A., Gaga, Mina, Haahtela, Tari, Illario, Maddalena, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T. T., Larenas-Linnemann, Desiree, Laune, Daniel, Lourenço, Olga M., Menditto, Enrica, Mullol, Joaquin, Okamoto, Yashitaka, Papadopoulos, Nikos, Pham-Thi, Nhân, Picard, Robert, Pinnock, Hilary, Roche, Nicolas, Roller-Wirnsberger, Regina E., Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Vasankari, Tuula, Ventura, Maria-Teresa, Walker, Samantha, Williams, Sian, Akdis, Cezmi A., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, Bateman, Eric, Bedbrook, Anna, Bennoor, K. 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W., Aberer, W., Agache, I., Akdis, C. A., Akdis, M., Aliberti, M. R., Almeida, R., Amat, F., Angles, R., Annesi-Maesano, I., Ansotegui, I. J., Anto, J. M., Arnavielle, S., Asayag, E., Asarnoj, A., Arshad, H., Avolio, F., Bacci, E., Bachert, C., Baiardini, I., Barbara, C., Barbagallo, M., Baroni, I., Barreto, B. A., Basagana, X., Bateman, E. D., Bedolla-Barajas, M., Bedbrook, A., Bewick, M., Beghé, B., Bel, E. H., Bergmann, K. C., Benson, M., Bertorello, L., Białoszewski, A. Z., Bieber, T., Bialek, S., Bindslev-Jensen, C., Bjermer, L., Blain, H., Blasi, F., Blua, A., Bochenska Marciniak, M., Bogus-Buczynska, I., the ARIA Study Group, the MASK Study Group, Briedis, Vitalis, uBibliorum, Yiallouros, Panayiotis K. [0000-0002-8339-9285], Costa, Elisio [0000-0003-1158-1480], Kritikos, Vicky [0000-0003-3955-0002], Gaga, Mina [0000-0002-9949-6012], Prokopakis, Emmanuel P. [0000-0002-1208-1990], Togias, Alkis [0000-0001-9009-5717], Erhola, Marina [0000-0002-1364-9023], Bosnic-Anticevich, Sinthia [0000-0001-5077-8329], Lourenço, Olga M. [0000-0002-8401-5976], Ierodiakonou, Despo [0000-0002-7862-2016], Health Services Management & Organisation (HSMO), Obstetrics & Gynecology, Universidade do Minho, Laboratoire de Génie Informatique et Ingénierie de Production (LGI2P), IMT - MINES ALES (IMT - MINES ALES), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Bousquet, J. J., Schunemann, H. J., Togias, A., Erhola, M., Hellings, P. W., Zuberbier, T., Agache, I., Ansotegui, I. J., Anto, J. M., Bachert, C., Becker, S., Bedolla-Barajas, M., Bewick, M., Bosnic-Anticevich, S., Bosse, I., Boulet, L. P., Bourrez, J. M., Brusselle, G., Chavannes, N., Costa, E., Cruz, A. A., Czarlewski, W., Fokkens, W. J., Fonseca, J. A., Gaga, M., Haahtela, T., Illario, M., Klimek, L., Kuna, P., Kvedariene, V., Le, L. T. T., Larenas-Linnemann, D., Laune, D., Lourenco, O. M., Menditto, E., Mullol, J., Okamoto, Y., Papadopoulos, N., Pham-Thi, N., Picard, R., Pinnock, H., Roche, N., Roller-Wirnsberger, R. E., Rolland, C., Samolinski, B., Sheikh, A., Toppila-Salmi, S., Tsiligianni, I., Valiulis, A., Valovirta, E., Vasankari, T., Ventura, M. -T., Walker, S., Williams, S., Akdis, C. A., Annesi-Maesano, I., Arnavielhe, S., Basagana, X., Bateman, E., Bedbrook, A., Bennoor, K. S., Benveniste, S., Bergmann, K. C., Bialek, S., Billo, N., Bindslev-Jensen, C., Bjermer, L., Blain, H., Bonini, M., Bonniaud, P., Bouchard, J., Briedis, V., Brightling, C. E., Brozek, J., Buhl, R., Buonaiuto, R., Canonica, G. W., Cardona, V., Carriazo, A. M., Carr, W., Cartier, C., Casale, T., Cecchi, L., Cepeda Sarabia, A. M., Chkhartishvili, E., Chu, D. K., Cingi, C., Colgan, E., De Sousa, J. C., Courbis, A. L., Custovic, A., Cvetkosvki, B., Damato, G., Da Silva, J., Dantas, C., Dokic, D., Dauvilliers, Y., Dedeu, A., De Feo, G., Devillier, P., Di Capua, S., Dykewickz, M., Dubakiene, R., Ebisawa, M., El-Gamal, Y., Eller, E., Emuzyte, R., Farrell, J., Fink-Wagner, A., Fiocchi, A., Fontaine, J. F., Gemicioglu, B., Schmid-Grendelmeir, P., Gamkrelidze, A., Garcia-Aymerich, J., Gomez, M., Diaz, S. G., Gotua, M., Guldemond, N. A., Guzman, M. -A., Hajjam, J., O'Hourihane, J. B., Humbert, M., Iaccarino, G., Ierodiakonou, D., Ivancevich, J. C., Joos, G., Jung, K. -S., Jutel, M., Kaidashev, I., Kalayci, O., Kardas, P., Keil, T., Khaitov, M., Khaltaev, N., Kleine-Tebbe, J., Kowalski, M. L., Kritikos, V., Kull, I., Leonardini, L., Lieberman, P., Lipworth, B., Lodrup Carlsen, K. C., Loureiro, C. C., Louis, R., Mair, A., Marien, G., Mahboub, B., Malva, J., Manning, P., De Manuel Keenoy, E., Marshall, G. D., Masjedi, M. R., Maspero, J. F., Mathieu-Dupas, E., Matricardi, P. M., Melen, E., Melo-Gomes, E., Meltzer, E. O., Mercier, J., Miculinic, N., Mihaltan, F., Milenkovic, B., Moda, G., Mogica-Martinez, M. -D., Mohammad, Y., Montefort, S., Monti, R., Morais-Almeida, M., Mosges, R., Munter, L., Muraro, A., Murray, R., Naclerio, R., Napoli, L., Namazova-Baranova, L., Neffen, H., Nekam, K., Neou, A., Novellino, E., Nyembue, D., O'Hehir, R., Ohta, K., Okubo, K., Onorato, G., Ouedraogo, S., Pali-Scholl, I., Palkonen, S., Panzner, P., Park, H. -S., Pepin, J. -L., Pereira, A. -M., Pfaar, O., Paulino, E., Phillips, J., Plavec, D., Popov, T. A., Portejoie, F., Price, D., Prokopakis, E. P., Pugin, B., Raciborski, F., Rajabian-Soderlund, R., Reitsma, S., Rodo, X., Romano, A., Rosario, N., Rottem, M., Ryan, D., Salimaki, J., Sanchez-Borges, M. M., Sisul, J. -C., Sole, D., Somekh, D., Sooronbaev, T., Sova, M., Spranger, O., Stellato, C., Stelmach, R., Ulrik, C. S., Thibaudon, M., To, T., Todo-Bom, A., Tomazic, P. V., Valero, A. A., Valenta, R., Valentin-Rostan, M., Van Der Kleij, R., Vandenplas, O., Vezzani, G., Viart, F., Viegi, G., Wallace, D., Wagenmann, M., Wang, D. Y., Waserman, S., Wickman, M., Williams, D. M., Wong, G., Wroczynski, P., Yiallouros, P. K., Yorgancioglu, A., Yusuf, O. M., Zar, H. J., Zeng, S., Zernotti, M., Zhang, L., Zhong, N. S., Zidarn, M., UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, and UCL - (MGD) Service de pneumologie

Subjects
Allergy, IMPACT, Respiratory Medicine and Allergy, ARIA Study Group, Health care transformation, Care pathways, Rhinitis, ARIA, MASK, POLLAR, Review, GUIDELINES, Medical and Health Sciences, PATIENT-CARE, 0302 clinical medicine, immune system diseases, 11. Sustainability, Health care, Medicine and Health Sciences, Outras Ciências Médicas [Ciências Médicas], Immunology and Allergy, Medicine, 030212 general & internal medicine, mHealth, health care economics and organizations, Lungmedicin och allergi, Rhinitis, Self-management, 616.2 [udc], Environmental exposure, POLLAR, 3. Good health, CHRONIC RESPIRATORY-DISEASES, Care pathways, HEALTH, Life Sciences & Biomedicine, Pulmonary and Respiratory Medicine, SEASONAL ALLERGIC RHINITIS, medicine.medical_specialty, animal structures, MASK, Health care transformation, EUROPEAN INNOVATION PARTNERSHIP, ARIA, Immunology, Health literacy, 03 medical and health sciences, INTERMITTENT, BUDESONIDE-FORMOTEROL, As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement, Air pollutants, adverse effects, Air pollution, Asthma, physiopathology, physiopathology [In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body], Patient participation, SELF-MANAGEMENT, MASK Study Group, Ciências Médicas::Outras Ciências Médicas, udc:616.2, Care pathway, Science & Technology, business.industry, RC581-607, medicine.disease, respiratory tract diseases, Integrated care, 030228 respiratory system, 13. Climate action, Family medicine, Immunologic diseases. Allergy, Clinical Medicine, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted “patient activation”, (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement., Partly funded by POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), and ARIA.

Published
2019
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19. ARIA digital anamorphosis:Digital transformation of health and care in airway diseases from research to practice

Author

Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T.T., Larenas-Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga M., Melén, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaëla, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhân, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagaña, Xavier, D. Bateman, Eric, Bédard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean François, Fuentes Perez, José M., Gemicioğlu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, René Maximiliano, González Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michaël, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralph, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Björn, Novellino, Ettore, Nyembue, Dieudonné, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Schöll, Isabella, Panzner, Peter, Park, Hae Sim, Passalacqua, Gianni, Pépin, Jean Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Söderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schünemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, François, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stéphane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, Zidarn, Mihaela, Bousquet, Jean, Anto, Josep M., Bachert, Claus, Haahtela, Tari, Zuberbier, Torsten, Czarlewski, Wienczyslawa, Bedbrook, Anna, Bosnic-Anticevich, Sinthia, Walter Canonica, G., Cardona, Victoria, Costa, Elisio, Cruz, Alvaro A., Erhola, Marina, Fokkens, Wytske J., Fonseca, Joao A., Illario, Maddalena, Ivancevich, Juan Carlos, Jutel, Marek, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T.T., Larenas-Linnemann, Désirée E., Laune, Daniel, Lourenço, Olga M., Melén, Erik, Mullol, Joaquim, Niedoszytko, Marek, Odemyr, Mikaëla, Okamoto, Yoshitaka, Papadopoulos, Nikos G., Patella, Vincenzo, Pfaar, Oliver, Pham-Thi, Nhân, Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Sofiev, Mikhail, Suppli Ulrik, Charlotte, Todo-Bom, Ana, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Ventura, Maria Teresa, Walker, Samantha, Williams, Sian, Yorgancioglu, Arzu, Agache, Ioana, Akdis, Cezmi A., Almeida, Rute, Ansotegui, Ignacio J., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagaña, Xavier, D. Bateman, Eric, Bédard, Annabelle, Bedolla-Barajas, Martin, Becker, Sven, Bennoor, Kazi S., Benveniste, Samuel, Bergmann, Karl C., Bewick, Michael, Bialek, Slawomir, E. Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Matteo, Bonniaud, Philippe, Bosse, Isabelle, Bouchard, Jacques, Boulet, Louis Philippe, Bourret, Rodolphe, Boussery, Koen, Braido, Fluvio, Briedis, Vitalis, Briggs, Andrew, Brightling, Christopher E., Brozek, Jan, Brusselle, Guy, Brussino, Luisa, Buhl, Roland, Buonaiuto, Roland, Calderon, Moises A., Camargos, Paulo, Camuzat, Thierry, Caraballo, Luis, Carriazo, Ana Maria, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., H. Chavannes, Niels, Chkhartishvili, Ekaterine, Chu, Derek K., Cingi, Cemal, Correia de Sousa, Jaime, Costa, David J., Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, D'Amato, Gennaro, da Silva, Jane, Dantas, Carina, Dokic, Dejan, Dauvilliers, Yves, De Feo, Giulia, De Vries, Govert, Devillier, Philippe, Di Capua, Stefania, Dray, Gerard, Dubakiene, Ruta, Durham, Stephen R., Dykewicz, Marc, Ebisawa, Motohiro, Gaga, Mina, El-Gamal, Yehia, Heffler, Enrico, Emuzyte, Regina, Farrell, John, Fauquert, Jean Luc, Fiocchi, Alessandro, Fink-Wagner, Antje, Fontaine, Jean François, Fuentes Perez, José M., Gemicioğlu, Bilun, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gevaert, Philippe, Gomez, René Maximiliano, González Diaz, Sandra, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria Antonieta, Hajjam, Jawad, Huerta Villalobos, Yunuen R., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Iinuma, Tomohisa, Jassem, Ewa, Joos, Guy, Jung, Ki Suck, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Musa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kouznetsov, Rostislav, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, La Grutta, Stefania, Leonardini, Lisa, Ljungberg, Henrik, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Lopes-Pereira, Catarina, Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Mahboub, Bassam, Makris, Michaël, Malva, Joao, Manning, Patrick, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Carreiro-Martins, Pedro, Makela, Mika, Mathieu-Dupas, Eve, Maurer, Marcus, De Manuel Keenoy, Esteban, Melo-Gomes, Elisabete, Meltzer, Eli O., Menditto, Enrica, Mercier, Jacques, Micheli, Yann, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Mitsias, Dimitirios I., Moda, Giuliana, Mogica-Martinez, Maria Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralph, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leyla, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Nordlund, Björn, Novellino, Ettore, Nyembue, Dieudonné, O'Hehir, Robyn, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle L., Orlando, Valentina, Ouedraogo, Solange, Palamarchuk, Julia, Pali-Schöll, Isabella, Panzner, Peter, Park, Hae Sim, Passalacqua, Gianni, Pépin, Jean Louis, Paulino, Ema, Pawankar, Ruby, Phillips, Jim, Picard, Robert, Pinnock, Hilary, Plavec, Davor, Popov, Todor A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Psarros, Fotis, Pugin, Benoit, Puggioni, Francesca, Quinones-Delgado, Pablo, Raciborski, Filip, Rajabian-Söderlund, Rojin, Regateiro, Frederico S., Reitsma, Sietze, Rivero-Yeverino, Daniela, Roberts, Graham, Roche, Nicolas, Rodriguez-Zagal, Erendira, Roller-Wirnsberger, Regina E., Rosario, Nelson, Romano, Antonino, Rottem, Menachem, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sastre, Joaquin, Scadding, Glenis K., Scheire, Sophie, Schmid-Grendelmeier, Peter, Schünemann, Holger J., Sarquis Serpa, Faradiba, Shamji, Mohamed, Sisul, Juan Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spertini, François, Spranger, Otto, Stellato, Cristiana, Stelmach, Rafael, Thibaudon, Michel, To, Teresa, Toumi, Mondher, Usmani, Omar, Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Pereira, Marilyn Urrutia, van der Kleij, Rianne, Van Eerd, Michiel, Vandenplas, Olivier, Vasankari, Tuula, Vaz Carneiro, Antonio, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Yun, Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yusuf, Osman M., Zar, Heather J., Zeng, Stéphane, Zernotti, Mario E., Zhang, Luo, Shan Zhong, Nan, and Zidarn, Mihaela

Abstract

Digital anamorphosis is used to define a distorted image of health and care that may be viewed correctly using digital tools and strategies. MASK digital anamorphosis represents the process used by MASK to develop the digital transformation of health and care in rhinitis. It strengthens the ARIA change management strategy in the prevention and management of airway disease. The MASK strategy is based on validated digital tools. Using the MASK digital tool and the CARAT online enhanced clinical framework, solutions for practical steps of digital enhancement of care are proposed.

Published
2020

20. ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice

Author

Bousquet, Jean, primary, Anto, Josep M., additional, Bachert, Claus, additional, Haahtela, Tari, additional, Zuberbier, Torsten, additional, Czarlewski, Wienczyslawa, additional, Bedbrook, Anna, additional, Bosnic‐Anticevich, Sinthia, additional, Walter Canonica, G., additional, Cardona, Victoria, additional, Costa, Elisio, additional, Cruz, Alvaro A., additional, Erhola, Marina, additional, Fokkens, Wytske J., additional, Fonseca, Joao A., additional, Illario, Maddalena, additional, Ivancevich, Juan‐Carlos, additional, Jutel, Marek, additional, Klimek, Ludger, additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Le, LTT, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Lourenço, Olga M., additional, Melén, Erik, additional, Mullol, Joaquim, additional, Niedoszytko, Marek, additional, Odemyr, Mikaëla, additional, Okamoto, Yoshitaka, additional, Papadopoulos, Nikos G., additional, Patella, Vincenzo, additional, Pfaar, Oliver, additional, Pham‐Thi, Nhân, additional, Rolland, Christine, additional, Samolinski, Boleslaw, additional, Sheikh, Aziz, additional, Sofiev, Mikhail, additional, Suppli Ulrik, Charlotte, additional, Todo‐Bom, Ana, additional, Tomazic, Peter‐Valentin, additional, Toppila‐Salmi, Sanna, additional, Tsiligianni, Ioanna, additional, Valiulis, Arunas, additional, Valovirta, Erkka, additional, Ventura, Maria‐Teresa, additional, Walker, Samantha, additional, Williams, Sian, additional, Yorgancioglu, Arzu, additional, Agache, Ioana, additional, Akdis, Cezmi A., additional, Almeida, Rute, additional, Ansotegui, Ignacio J., additional, Annesi‐Maesano, Isabella, additional, Arnavielhe, Sylvie, additional, Basagaña, Xavier, additional, D. Bateman, Eric, additional, Bédard, Annabelle, additional, Bedolla‐Barajas, Martin, additional, Becker, Sven, additional, Bennoor, Kazi S., additional, Benveniste, Samuel, additional, Bergmann, Karl C., additional, Bewick, Michael, additional, Bialek, Slawomir, additional, E. Billo, Nils, additional, Bindslev‐Jensen, Carsten, additional, Bjermer, Leif, additional, Blain, Hubert, additional, Bonini, Matteo, additional, Bonniaud, Philippe, additional, Bosse, Isabelle, additional, Bouchard, Jacques, additional, Boulet, Louis‐Philippe, additional, Bourret, Rodolphe, additional, Boussery, Koen, additional, Braido, Fluvio, additional, Briedis, Vitalis, additional, Briggs, Andrew, additional, Brightling, Christopher E., additional, Brozek, Jan, additional, Brusselle, Guy, additional, Brussino, Luisa, additional, Buhl, Roland, additional, Buonaiuto, Roland, additional, Calderon, Moises A., additional, Camargos, Paulo, additional, Camuzat, Thierry, additional, Caraballo, Luis, additional, Carriazo, Ana‐Maria, additional, Carr, Warner, additional, Cartier, Christine, additional, Casale, Thomas, additional, Cecchi, Lorenzo, additional, Cepeda Sarabia, Alfonso M., additional, H. Chavannes, Niels, additional, Chkhartishvili, Ekaterine, additional, Chu, Derek K., additional, Cingi, Cemal, additional, Correia de Sousa, Jaime, additional, Costa, David J., additional, Courbis, Anne‐Lise, additional, Custovic, Adnan, additional, Cvetkosvki, Biljana, additional, D'Amato, Gennaro, additional, da Silva, Jane, additional, Dantas, Carina, additional, Dokic, Dejan, additional, Dauvilliers, Yves, additional, De Feo, Giulia, additional, De Vries, Govert, additional, Devillier, Philippe, additional, Di Capua, Stefania, additional, Dray, Gerard, additional, Dubakiene, Ruta, additional, Durham, Stephen R., additional, Dykewicz, Mark, additional, Ebisawa, Motohiro, additional, Gaga, Mina, additional, El‐Gamal, Yehia, additional, Heffler, Enrico, additional, Emuzyte, Regina, additional, Farrell, John, additional, Fauquert, Jean‐Luc, additional, Fiocchi, Alessandro, additional, Fink‐Wagner, Antje, additional, Fontaine, Jean‐François, additional, Fuentes Perez, José M., additional, Gemicioğlu, Bilun, additional, Gamkrelidze, Amiran, additional, Garcia‐Aymerich, Judith, additional, Gevaert, Philippe, additional, Gomez, René Maximiliano, additional, González Diaz, Sandra, additional, Gotua, Maia, additional, Guldemond, Nick A., additional, Guzmán, Maria‐Antonieta, additional, Hajjam, Jawad, additional, Huerta Villalobos, Yunuen R., additional, Humbert, Marc, additional, Iaccarino, Guido, additional, Ierodiakonou, Despo, additional, Iinuma, Tomohisa, additional, Jassem, Ewa, additional, Joos, Guy, additional, Jung, Ki‐Suck, additional, Kaidashev, Igor, additional, Kalayci, Omer, additional, Kardas, Przemyslaw, additional, Keil, Thomas, additional, Khaitov, Musa, additional, Khaltaev, Nikolai, additional, Kleine‐Tebbe, Jorg, additional, Kouznetsov, Rostislav, additional, Kowalski, Marek L., additional, Kritikos, Vicky, additional, Kull, Inger, additional, La Grutta, Stefania, additional, Leonardini, Lisa, additional, Ljungberg, Henrik, additional, Lieberman, Philip, additional, Lipworth, Brian, additional, Lodrup Carlsen, Karin C., additional, Lopes‐Pereira, Catarina, additional, Loureiro, Claudia C., additional, Louis, Renaud, additional, Mair, Alpana, additional, Mahboub, Bassam, additional, Makris, Michaël, additional, Malva, Joao, additional, Manning, Patrick, additional, Marshall, Gailen D., additional, Masjedi, Mohamed R., additional, Maspero, Jorge F., additional, Carreiro‐Martins, Pedro, additional, Makela, Mika, additional, Mathieu‐Dupas, Eve, additional, Maurer, Marcus, additional, De Manuel Keenoy, Esteban, additional, Melo‐Gomes, Elisabete, additional, Meltzer, Eli O., additional, Menditto, Enrica, additional, Mercier, Jacques, additional, Micheli, Yann, additional, Miculinic, Neven, additional, Mihaltan, Florin, additional, Milenkovic, Branislava, additional, Mitsias, Dimitirios I., additional, Moda, Giuliana, additional, Mogica‐Martinez, Maria‐Dolores, additional, Mohammad, Yousser, additional, Montefort, Steve, additional, Monti, Ricardo, additional, Morais‐Almeida, Mario, additional, Mösges, Ralph, additional, Münter, Lars, additional, Muraro, Antonella, additional, Murray, Ruth, additional, Naclerio, Robert, additional, Napoli, Luigi, additional, Namazova‐Baranova, Leyla, additional, Neffen, Hugo, additional, Nekam, Kristoff, additional, Neou, Angelo, additional, Nordlund, Björn, additional, Novellino, Ettore, additional, Nyembue, Dieudonné, additional, O'Hehir, Robyn, additional, Ohta, Ken, additional, Okubo, Kimi, additional, Onorato, Gabrielle L., additional, Orlando, Valentina, additional, Ouedraogo, Solange, additional, Palamarchuk, Julia, additional, Pali‐Schöll, Isabella, additional, Panzner, Peter, additional, Park, Hae‐Sim, additional, Passalacqua, Gianni, additional, Pépin, Jean‐Louis, additional, Paulino, Ema, additional, Pawankar, Ruby, additional, Phillips, Jim, additional, Picard, Robert, additional, Pinnock, Hilary, additional, Plavec, Davor, additional, Popov, Todor A., additional, Portejoie, Fabienne, additional, Price, David, additional, Prokopakis, Emmanuel P., additional, Psarros, Fotis, additional, Pugin, Benoit, additional, Puggioni, Francesca, additional, Quinones‐Delgado, Pablo, additional, Raciborski, Filip, additional, Rajabian‐Söderlund, Rojin, additional, Regateiro, Frederico S., additional, Reitsma, Sietze, additional, Rivero‐Yeverino, Daniela, additional, Roberts, Graham, additional, Roche, Nicolas, additional, Rodriguez‐Zagal, Erendira, additional, Roller‐Wirnsberger, Regina E., additional, Rosario, Nelson, additional, Romano, Antonino, additional, Rottem, Menachem, additional, Ryan, Dermot, additional, Salimäki, Johanna, additional, Sanchez‐Borges, Mario M., additional, Sastre, Joaquin, additional, Scadding, Glenis K., additional, Scheire, Sophie, additional, Schmid‐Grendelmeier, Peter, additional, Schünemann, Holger J., additional, Sarquis Serpa, Faradiba, additional, Shamji, Mohamed, additional, Sisul, Juan‐Carlos, additional, Solé, Dirceu, additional, Somekh, David, additional, Sooronbaev, Talant, additional, Sova, Milan, additional, Spertini, François, additional, Spranger, Otto, additional, Stellato, Cristiana, additional, Stelmach, Rafael, additional, Thibaudon, Michel, additional, To, Teresa, additional, Toumi, Mondher, additional, Usmani, Omar, additional, Valero, Antonio A., additional, Valenta, Rudolph, additional, Valentin‐Rostan, Marylin, additional, Pereira, Marilyn Urrutia, additional, van der Kleij, Rianne, additional, Van Eerd, Michiel, additional, Vandenplas, Olivier, additional, Vasankari, Tuula, additional, Vaz Carneiro, Antonio, additional, Vezzani, Giorgio, additional, Viart, Frédéric, additional, Viegi, Giovanni, additional, Wallace, Dana, additional, Wagenmann, Martin, additional, Wang, De Yun, additional, Waserman, Susan, additional, Wickman, Magnus, additional, Williams, Dennis M., additional, Wong, Gary, additional, Wroczynski, Piotr, additional, Yiallouros, Panayiotis K., additional, Yusuf, Osman M., additional, Zar, Heather J., additional, Zeng, Stéphane, additional, Zernotti, Mario E., additional, Zhang, Luo, additional, Shan Zhong, Nan, additional, and Zidarn, Mihaela, additional

Published
2020
Full Text
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22. Managing Allergic Rhinitis in the Pharmacy: An ARIA Guide for Implementation in Practice

Author

Lourenço, Olga, primary, Bosnic-Anticevich, Sinthia, additional, Costa, Elísio, additional, Fonseca, João A., additional, Menditto, Enrica, additional, Cvetkovski, Biljana, additional, Kritikos, Vicky, additional, Tan, Rachel, additional, Bedbrook, Anna, additional, Scheire, Sophie, additional, Bachert, Claus, additional, Białek, Sławomir, additional, Briedis, Vitalis, additional, Boussery, Koen, additional, Canonica, G. Walter, additional, Haahtela, Tari, additional, Kuna, Piotr, additional, Novellino, Ettore, additional, Samoliński, Bolesław, additional, Schünemann, Holger J., additional, Wallace, Dana, additional, and Bousquet, Jean, additional

Published
2020
Full Text
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24. Вплив факторів способу життя на закреп - чи повинен фармацевт враховувати їх?

Author

Minkutė, Rima, Andrijauskaitė, Indrė, and Briedis, Vitalis

Subjects
частота запоров, питание, физические нагрузки, индекс массы тела, UDC 615, constipation frequency, nutrition, physical activity, body mass index
Abstract

Aim of this study was to analyze the influence of lifestyle (nutrition and physical activity) on constipation and evaluate the respondents’ attitude to this disorder.Methods. Pharmacy visitors who agreed to answer questions were included in the study. Data from respondents based on age (18-45 years old; 46-65 years old; above 65 years old) and body mass index (“normal,” “overweight,” “obese”) was analyzed. Nutrition and physical activity were analyzed for the purpose of identifying risk factors for constipation. Descriptive and comparative statistics were used – the respondents’ responses are presented in frequencies and percentages, Chi-square test was executed to measure association with knowledge, responses and gender, age, BMI.Results. The study identified a 12.8 % constant constipation rate in the study group with no significant differences between genders, however more males had no constipation problem (50.5 % vs 39.9 %). The age and body mass index had association with constipation (p, Целью этого исследования был анализ влияния образа жизни (питание и физических нагрузок) на запор и оценка отношения респондентов к этому расстройству.Методы. Посетители аптеки, которые согласились ответить на вопрос, были включены в исследование. Проанализированы данные респондентов на основе возраста (18-45 лет 46-65 лет старше 65 лет) и индекса массы тела ("нормально", "избыточный вес", "ожирение"). Питание и физические нагрузки были проанализированы с целью выявления факторов риска появления запора. Была использована описательная и сравнительная статистика - ответы респондентов представлены частотами и процентами, Хи-квадратный тест был выполнен для измерения ассоциации со знаниями, ответами и полом, возрастом, ИМТ.Результаты. В ходе исследования было установлено 12.8 % постоянной частоты запоров в исследуемой группе, независимо от пола, однако большинство мужчин не имели проблем с запорами (50.5 % против 39.9 %). Индекс массы тела и возраст был связан с запорами (р, Метою цього дослідження був аналіз впливу способу життя (харчування та фізичних навантажень) на закреп та оцінка ставлення респондентів до цього розладу.Методи. Відвідувачі аптеки, які погодились відповісти на запитання, були включені у дослідження. Проаналізовано дані респондентів на основі віку (18-45 років; 46-65 років; старше 65 років) та індексу маси тіла ("нормально", "надмірна вага", "ожиріння"). Харчування та фізичні навантаження були проаналізовані з метою виявлення факторів ризику появи закрепу. Була використана описова та порівняльна статистика - відповіді респондентів представлені частотами та відсотками, Хі-квадратний тест був виконаний для вимірювання асоціації зі знаннями, відповідями та статтю, віком, ІМТ.Результати. У ході дослідження було встановлено 12.8 % постійної частоти закрепів в досліджуваній групі, незалежно від статі, проте більшість чоловіків не мали проблем із закрепами (50.5 % проти 39.9 %). Індекс маси тіла та вік був пов'язаний із закрепами (р

Published
2019

25. ARIA pharmacy 2018: Allergic rhinitis care pathways for community pharmacy

Author

Bosnic-Anticevich, Sinthia, Costa, Elísio, Menditto, Enrica, Lourenço, Olga, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Buonaiuto, Roland, Chrystyn, Henry, Cvetkovski, Biljana, Di Capua, Stefania, Sousa, Jaime Correia de, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Philippe, Dykewicz, Mark S, Gaga, Mina, El-Gamal, Yehia, Fonseca, João, Fokkens, Wytske J, Kuna, Piotr, Kowalski, Marek, Guzmán, Maria Antonieta, Haahtela, Tari, Hellings, Peter W, Illario, Maddalena, Ivancevich, Juan Carlos, Just, Jocelyne, Kaidashev, Igor, Khaitov, Musa, Khaltaev, Nikolai, Keil, Thomas, Larenas-Linnemann, Désirée, Kvedariene, Violeta, Klimek, Ludger, Laune, Daniel, Le, Lan T T, Lodrup Carlsen, Karin C, Mahboub, Bassam, Maier, Dieter, Malva, João, Manning, Patrick J, Okamoto, Yoshitaka, Ohta, Ken, Almeida, Mário Morais, Mösges, Ralph, Mullol, Joaquim, Münter, Lars, Murray, Ruth, Naclerio, Robert, Namazova-Baranova, Leyla, Nekam, Kristof, Nyembue, Tshipukane Dieudonné, Okubo, Kimi, Palkonen, Susanna, Onorato, Gabrielle L, O'Hehir, Robyn E, Panzner, Petr, Papadopoulos, Nikolaos G, Park, Hae-Sim, Pawankar, Ruby, Pfaar, Oliver, Phillips, Jim, Plavec, Davor, Stellato, Cristiana, Somekh, David, Popov, Todor A, Potter, Paul C, Prokopakis, Emmanuel P, Roller-Wirnsberger, Regina E, Rottem, Menachem, Ryan, Dermot, Samolinski, Boleslaw, Sanchez-Borges, Mario, Schunemann, Holger J, Sheikh, Aziz, Todo-Bom, Ana Maria, To, Teresa, Sisul, Juan Carlos, Tomazic, Peter Valentin, Toppila-Salmi, Sanna, Valero, Antonio, Valiulis, Arunas, Valovirta, Errka, Ventura, Maria Teresa, Wagenmann, Martin, Kritikos, Vicky, Bousquet, Jean, Wallace, Dana, Waserman, Susan, Wickman, Magnus, Yiallouros, Panayiotis K, Yorgancioglu, Arzu, Yusuf, Osman M, Zar, Heather J, Zernotti, Mario E, Zhang, Luo, Zidarn, Mihaela, Orlando, Valentina, Mair, Alpana, Zuberbier, Torsten, Paulino, Ema, Salimäki, Johanna, Söderlund, Rojin, Tan, Rachel, Williams, Dennis M, Wroczynski, Piotr, Agache, Ioana, Ansotegui, Ignacio J, Cruz, Alvaro A, Anto, Josep M, Bedbrook, Anna, Bachert, Claus, Bewick, Mike, Bindslev-Jensen, Carsten, Brozek, Jan L, Canonica, Giorgio Walter, Cardona, Victoria, Carr, Warner, Casale, Thomas, Czarlewski, Wienczyslawa, Chavannes, Niels H, and uBibliorum

Subjects
Care pathways, Pharmacist, Allergic Rhinitis and its Impact on Asthma, Asthma, Rhinitis
Abstract

Pharmacists are trusted health care professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis. The Allergic Rhinitis and its Impact on Asthma (ARIA)-pharmacy ICP includes a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease, a systematic Diagnosis Guide (including differential diagnoses), and a simple flowchart with proposed treatment for rhinitis and asthma multimorbidity. Key prompts for referral within the ICP are included. The use of technology is critical to enhance the management of allergic rhinitis. However, the ARIA-pharmacy ICP should be adapted to local healthcare environments/situations as regional (national) differences exist in pharmacy care.

Published
2019

26. ARIA pharmacy 2018 'Allergic rhinitis care pathways for community pharmacy'

Author

Yiallouros, Panayiotis K., Larenas‐Linnemann, Désirée E., Bosnic‐Anticevich, Sinthia, Costa, Elisio, Menditto, Enrica, Lourenço, Olga, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Buonaiuto, Roland, Chrystyn, Henry, Cvetkovski, Biljana, Capua, Stefania Di, Kritikos, Vicky, Mair, Alpana, Orlando, Valentina, Paulino, Ema, Salimäki, Johanna, Söderlund, Rojin, Tan, Rachel, Williams, Dennis M., Wroczynski, Piotr, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bedbrook, Anna, Bachert, Claus, Bewick, Mike, Bindslev‐Jensen, Carsten, Brozek, Jan L., Canonica, Giorgio Walter, Cardona, Victoria, Carr, Warner, Casale, Thomas B., Chavannes, Niels H., Sousa, Jaime Correia de, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Carlo, Giuseppe De, Demoly, Pascal, Devillier, Philippe, Dykewicz, Mark S., Gaga, Mina, El‐Gamal, Yehia, Fonseca, João, Fokkens, Wytske J., Guzmán, Maria Antonieta, Haahtela, Tari, Hellings, Peter W., Illario, Maddalena, Ivancevich, Juan Carlos, Just, Jocelyne, Kaidashev, Igor, Khaitov, Musa, Khaltaev, Nikolai, Keil, Thomas, Klimek, Ludger, Kowalski, Marek L., Kuna, Piotr, Kvedariene, Violeta, Laune, Daniel, Le, Lan T. T., Carlsen, Karin C. Lodrup, Mahboub, Bassam, Maier, Dieter, Malva, Joao, Manning, Patrick J., Morais‐Almeida, Mário, Mösges, Ralph, Mullol, Joaquim, Münter, Lars, Murray, Ruth, Naclerio, Robert, Namazova‐Baranova, Leyla, Nekam, Kristof, Nyembue, Tshipukane Dieudonné, Okubo, Kimi, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L., Palkonen, Susanna, Panzner, Petr, Papadopoulos, Nikolaos G., Park, Hae-Sim, Pawankar, Ruby, Pfaar, Oliver, Phillips, Jim, Plavec, Davor, Popov, Todor A., Potter, Paul C., Prokopakis, Emmanuel P., Roller‐Wirnsberger, Regina E., Rottem, Menachem, Ryan, Dermot, Samolinski, Bolesław, Sanchez‐Borges, Mario, Schunemann, Holger J., Sheikh, Aziz, Sisul, Juan Carlos, Somekh, David, Stellato, Cristiana, To, Teresa, Todo‐Bom, Ana Maria, Tomazic, Peter Valentin, Toppila‐Salmi, Sanna, Valero, Antonio, Valiulis, Arunas, Valovirta, Errka, Ventura, Maria Teresa, Wagenmann, Martin, Wallace, Dana, Waserman, Susan, Wickman, Magnus, Yorgancioglu, Arzu, Yusuf, Osman M., Zar, Heather J., Zernotti, Mario E., Zhang, Luo, Zidarn, Mihaela, Zuberbier, Torsten, Bousquet, Jean, Yiallouros, Panayiotis K. [0000-0002-8339-9285], Costa, Elisio [0000-0003-1158-1480], Kritikos, Vicky [0000-0003-3955-0002], Gaga, Mina [0000-0002-9949-6012], Papadopoulos, Nikolaos G. [0000-0002-4448-3468], and Prokopakis, Emmanuel P. [0000-0002-1208-1990]

Abstract

Pharmacists are trusted health care professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis. The Allergic Rhinitis and its Impact on Asthma (ARIA)-pharmacy ICP includes a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease, a systematic Diagnosis Guide (including differential diagnoses), and a simple flowchart with proposed treatment for rhinitis and asthma multimorbidity. Key prompts for referral within the ICP are included. The use of technology is critical to enhance the management of allergic rhinitis. However, the ARIA-pharmacy ICP should be adapted to local healthcare environments/situations as regional (national) differences exist in pharmacy care. 74 7 1219 1236

Published
2019
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27. MOESM1 of Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

Author

J. Bousquet, Schünemann, Holger, Togias, Alkis, Erhola, Marina, Hellings, Peter, Zuberbier, Torsten, Agache, Ioana, Ansotegui, Ignacio, Anto, Josep, Bachert, Claus, Becker, Sven, Bedolla-Barajas, Martin, Bewick, Michael, Sinthia Bosnic-Anticevich, Bosse, Isabelle, Boulet, Louis, Bourrez, Jean, Brusselle, Guy, Chavannes, Niels, Elisio Costa, Cruz, Alvaro, Wienczyslawa Czarlewski, Fokkens, Wytske, Joao Fonseca, Gaga, Mina, Tari Haahtela, Illario, Maddalena, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, L. Le, Larenas-Linnemann, Desiree, Laune, Daniel, LourençO, Olga, Menditto, Enrica, Joaquin Mullol, Yashitaka Okamoto, Papadopoulos, Nikos, NhâN Pham-Thi, Picard, Robert, Pinnock, Hilary, Roche, Nicolas, Roller-Wirnsberger, Regina, Rolland, Christine, Boleslaw Samolinski, Sheikh, Aziz, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Arunas Valiulis, Valovirta, Erkka, Vasankari, Tuula, Maria-Teresa Ventura, Walker, Samantha, Williams, Sian, Akdis, Cezmi, Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, Bateman, Eric, Bedbrook, Anna, K. Bennoor, Benveniste, Samuel, Bergmann, Karl, Slawomir Bialek, Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Mateo, Bonniaud, Philippe, Bouchard, Jacques, Briedis, Vitalis, Brightling, Christofer, Brozek, Jan, Buhl, Roland, Buonaiuto, Roland, Giorgo Canonica, Cardona, Victoria, Carriazo, Ana, Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Sarabia, Alfonso Cepeda, Chkhartishvili, Eka, Chu, Derek, Cingi, Cemal, Colgan, Elaine, Sousa, Jaime, Courbis, Anne, Custovic, Adnan, Cvetkosvki, Biljana, D’Amato, Gennaro, Silva, Jane, Dantas, Carina, Dejand Dokic, Dauvilliers, Yves, Dedeu, Antoni, Feo, Giulia, Devillier, Philippe, Capua, Stefania, Dykewickz, Marc, Dubakiene, Ruta, Ebisawa, Motohiro, Yaya El-Gamal, Eller, Esben, Emuzyte, Regina, Farrell, John, Antjie Fink-Wagner, Fiocchi, Alessandro, Fontaine, Jean, Bilun GemicioğLu, Schmid-Grendelmeir, Peter, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Guldemond, Nick, Maria-Antonieta Guzmán, Hajjam, Jawad, Hourihane, John O’B, Humbert, Marc, Iaccarino, Guido, Despo Ierodiakonou, Ivancevich, Juan, Joos, Guy, Ki-Suck Jung, Jutel, Marek, Kaidashev, Igor, Kalayci, Omer, Przemyslaw Kardas, Keil, Thomas, Mussa Khaitov, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kowalski, Marek, Kritikos, Vicky, Kull, Inger, Leonardini, Lisa, Lieberman, Philip, Lipworth, Brian, Carlsen, Karin Lodrup, Loureiro, Claudia, Louis, Renaud, Alpana Mair, Marien, Gert, Mahboub, Bassam, Joao Malva, Manning, Patrick, Keenoy, Esteban Manuel, Gailen Marshall, Masjedi, Mohamed, Maspero, Jorge, Mathieu-Dupas, Eve, Poalo Matricardi, Melén, Eric, Melo-Gomes, Elisabete, Meltzer, Eli, Mercier, Jacques, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Moda, Giuliana, Maria-Dolores Mogica-Martinez, Yousser Mohammad, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralf, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leila, Neffen, Hugo, Kristoff Nekam, Neou, Angelo, Novellino, Enrico, Dieudonné Nyembue, O’Hehir, Robin, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle, Ouedraogo, Solange, Pali-Schöll, Isabella, Palkonen, Susanna, Panzner, Peter, Hae-Sim Park, Jean-Louis Pépin, Ana-Maria Pereira, Pfaar, Oliver, Paulino, Ema, Phillips, Jim, Plavec, Davor, Popov, Ted, Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel, Benoit Pugin, Raciborski, Filip, Rojin Rajabian-Söderlund, Reitsma, Sietze, Rodo, Xavier, Romano, Antonino, Rosario, Nelson, Menahenm Rottem, Ryan, Dermot, SalimäKi, Johanna, Sanchez-Borges, Mario, Juan-Carlos Sisul, Dirceu Solé, Somekh, David, Talant Sooronbaev, Sova, Milan, Spranger, Otto, Stellato, Cristina, Stelmach, Rafael, Ulrik, Charlotte Suppli, Thibaudon, Michel, To, Teresa, Todo-Bom, Ana, Tomazic, Peter, Valero, Antonio, Valenta, Rudolph, Valentin-Rostan, Marylin, Kleij, Rianne, Vandenplas, Olivier, Vezzani, Giorgio, Frédéric Viart, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De, Waserman, Susan, Wickman, Magnus, Williams, Dennis, Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis, Yorgancioglu, Arzu, Yusuf, Osman, Heahter Zar, Stéphane Zeng, Zernotti, Mario, Zhang, Luo, Zhong, Nan, and Zidarn, Mihaela

Abstract

Additional file 1. The MASK Study Group.

Published
2019
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28. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

Author

Bousquet, J. Jean Schunemann, Holger J. Togias, Alkis and Erhola, Marina Hellings, Peter W. Zuberbier, Torsten Agache, Ioana Ansotegui, Ignacio J. Anto, Josep M. Bachert, Claus and Becker, Sven Bedolla-Barajas, Martin Bewick, Michael and Bosnic-Anticevich, Sinthia Bosse, Isabelle Boulet, Louis P. and Bourrez, Jean Marc Brusselle, Guy Chavannes, Niels Costa, Elisio Cruz, Alvaro A. Czarlewski, Wienczyslawa Fokkens, Wytske J. Fonseca, Joao A. Gaga, Mina Haahtela, Tari and Illario, Maddalena Klimek, Ludger Kuna, Piotr Kvedariene, Violeta Le, L. T. T. Larenas-Linnemann, Desiree Laune, Daniel Lourenco, Olga M. Menditto, Enrica Mullo, Joaquin and Okamoto, Yashitaka Papadopoulos, Nikos Nhan Pham-Thi Picard, Robert Pinnock, Hilary Roche, Nicolas Roller-Wirnsberger, Regina E. Rolland, Christine Samolinski, Boleslaw Sheikh, Aziz Toppila-Salmi, Sanna Tsiligianni, Ioanna Valiulis, Arunas Valovirta, Erkka Vasankari, Tuula Ventura, Maria-Teresa Walker, Samantha Williams, Sian Akdis, Cezmi A. and Annesi-Maesano, Isabella Arnavielhe, Sylvie Basagana, Xavier and Bateman, Eric Bedbrook, Anna Bennoor, K. S. Benveniste, Samuel Bergmann, Karl C. Bia, Slawomir Billo, Nils and Bindslev-Jensen, Carsten Bjermer, Leif Blain, Hubert Bonini, Mateo Bonniaud, Philippe Bouchard, Jacques Briedis, Vitalis and Brightling, Christofer E. Brozek, Jan Buhl, Roland and Buonaiuto, Roland Canonica, Giorgo W. Cardona, Victoria and Carriazo, Ana M. Carr, Warner Cartier, Christine Casale, Thomas Cecchi, Lorenzo Cepeda Sarabia, Alfonso M. and Chkhartishvili, Eka Chu, Derek K. Cingi, Cemal Colgan, Elaine de Sousa, Jaime Correia Courbis, Anne Lise Custovic, Adnan Cvetkosvki, Biljana D'Amato, Gennaro da Silva, Jane and Dantas, Carina Dokic, Dejand Dauvilliers, Yves Dedeu, Antoni De Feo, Giulia Devillier, Philippe Di Capua, Stefania and Dykewickz, Marc Dubakiene, Ruta Ebisawa, Motohiro and El-Gamal, Yaya Eller, Esben Emuzyte, Regina Farrell, John and Fink-Wagner, Antjie Fiocchi, Alessandro Fontaine, Jean F. and Gemicioglu, Bilun Schmid-Grendelmeir, Peter Gamkrelidze, Amiran Garcia-Aymerich, Judith Gomez, Maximiliano Gonzalez Diaz, Sandra Gotua, Maia Guldemond, Nick A. Guzman, Maria-Antonieta Hajjam, Jawad Hourihane, John O'B Humbert, Marc Iaccarino, Guido Ierodiakonou, Despo Ivancevich, Juan C. Joos, Guy Jung, Ki-Suck Jutel, Marek Kaidashev, Igor and Kalayci, Omer Kardas, Przemyslaw Keil, Thomas Khaitov, Mussa Khaltaev, Nikolai Kleine-Tebbe, Jorg Kowalski, Marek L. Kritikos, Vicky Kull, Inger Leonardini, Lisa and Lieberman, Philip Lipworth, Brian Carlsen, Karin C. Lodrup and Loureiro, Claudia C. Louis, Renaud Mair, Alpana Marien, Gert and Mahboub, Bassam Malva, Joao Manning, Patrick Keenoy, Esteban De Manuel Marshall, Gallen D. Masjedi, Mohamed R. and Maspero, Jorge F. Mathieu-Dupas, Eve Matricardi, Poalo M. and Melen, Eric Melo-Gomes, Elisabete Meltzer, Eli O. Mercier, Jacques Miculinic, Neven Mihaltan, Florin Milenkovic, Branislava Moda, Giuliana Mogica-Martinezl, Maria-Dolores and Mohammad, Yousser Montefort, Steve Monti, Ricardo and Morais-Almeida, Mario Moesges, Raft Munter, Lars Muraro, Antonella Murray, Ruth Naclerio, Robert Napoli, Luigi and Namazova-Baranova, Leila Neffen, Hugo Nekam, Kristoff Neou, Angelo Novellino, Enrico Nyembue, Dieudonne O'Hehir, Robin and Ohta, Ken Okubo, Kimi Onorato, Gabrielle Ouedraogo, Solange Pali-Schoell, Isabella Palkonen, Susanna Panzner, Peter Park, Hae-Sim Pepin, Jean-Louis Pereira, Ana-Maria and Pfaar, Oliver Paulino, Ema Phillips, Jim Plavec, Davor and Popov, Ted A. Portejoie, Fabienne Price, David Prokopakis, Emmanuel P. Pugin, Benoit Raciborski, Filip and Rajabian-Soderlund, Rojin Reitsma, Sietze Rodo, Xavier and Romano, Antonino Rosario, Nelson Rottem, Menahenm Ryan, Dermot Salimaki, Johanna Sanchez-Borges, Mario M. Sisul, Juan-Carlos Sole, Dirceu Somekh, David Sooronbaev, Talant and Sova, Milan Spranger, Otto Stellato, Cristina Stelmach, Rafael Ulrik, Charlotte Suppli Thibaudon, Michel To, Teresa and Todo-Bom, Ana Tomazic, V, Peter Valero, Antonio A. and Valenta, Rudolph Valentin-Rostan, Marylin van der Kleij, Rianne and Vandenplas, Olivier Vezzani, Giorgio Viart, Frederic and Vieg, Giovanni Wallace, Dana Wagenmann, Martin Wang, De Y. and Waserman, Susan Wickman, Magnus Williams, Dennis M. and Wong, Gary Wroczynski, Piotr Yiallouros, Panayiotis K. and Yorgancioglu, Arzu Yusuf, Osman M. Zar, Heahter J. Zeng, Stephane Zernotti, Mario Zhang, Luo Zhong, Nan S. and Zidarn, Mihaela ARIA Study Grp MASK Study Grp

Abstract

Background In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted “patient activation”, (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Sante as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.

Published
2019

29. Adherence to treatment in allergic rhinitis using mobile technology : the MASK Study

Author

Menditto, Enrica, Costa, Elisio, Midão, Luis, Bosnic-Anticevich, Sinthia, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Mair, Alpana, Rajabian-Soderlund, Rojin, Arnavielhe, Sylvie, Bedbrook, Anna, Czarlewski, Wienczyslawa, Annesi-Maesano, Isabella, Anto, Josep M., Devillier, Philippe, De Vries, Govert, Keil, Thomas, Sheikh, Aziz, Orlando, Valentina, Larenas-Linnemann, Désirée, Cecchi, Lorenzo, De Feo, Giulia, Illario, M., Stellato, Christiana, Fonseca, Joao, Malva, Joao, Morais-Almeida, Mario, Pereira, Ana Maria, Todo-Bom, Ana Maria, Kvedariene, Violeta, Valiulis, Arunas, Bergmann, Karl Christian, Klimek, Ludger, Mösges, Ralph, Pfaar, Oliver, Zuberbier, Torsten, Cardona, Vicky, Mullol, Joaquim, Papadopoulos, Nikos G., Prokopakis, Emmanuel P., Bewick, Mike, Ryan, Dermot, Roller-Wirnsberger, Regina E., Tomazic, Peter Valentin, Cruz, Alvaro A., Kuna, Piotr, Samolinski, Boleslaw, Fokkens, Wytske J., Reitsma, Sietze, Bosse, Isabelle, Fontaine, Jean-François, Laune, Daniel, Haahtela, Tari, Toppila-Salmi, Sanna, Bachert, Claus, Hellings, Peter W., Melén, Erik, Wickman, Magnus, Bindslev-Jensen, Carsten, Eller, Esben, O'Hehir, Robyn E., Cingi, Cemal, Gemicioğlu, Bilun, Kalayci, Omer, Ivancevich, Juan Carlos, Bousquet, Jean, Menditto, Enrica, Costa, Elisio, Midão, Luis, Bosnic-Anticevich, Sinthia, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Mair, Alpana, Rajabian-Soderlund, Rojin, Arnavielhe, Sylvie, Bedbrook, Anna, Czarlewski, Wienczyslawa, Annesi-Maesano, Isabella, Anto, Josep M., Devillier, Philippe, De Vries, Govert, Keil, Thomas, Sheikh, Aziz, Orlando, Valentina, Larenas-Linnemann, Désirée, Cecchi, Lorenzo, De Feo, Giulia, Illario, M., Stellato, Christiana, Fonseca, Joao, Malva, Joao, Morais-Almeida, Mario, Pereira, Ana Maria, Todo-Bom, Ana Maria, Kvedariene, Violeta, Valiulis, Arunas, Bergmann, Karl Christian, Klimek, Ludger, Mösges, Ralph, Pfaar, Oliver, Zuberbier, Torsten, Cardona, Vicky, Mullol, Joaquim, Papadopoulos, Nikos G., Prokopakis, Emmanuel P., Bewick, Mike, Ryan, Dermot, Roller-Wirnsberger, Regina E., Tomazic, Peter Valentin, Cruz, Alvaro A., Kuna, Piotr, Samolinski, Boleslaw, Fokkens, Wytske J., Reitsma, Sietze, Bosse, Isabelle, Fontaine, Jean-François, Laune, Daniel, Haahtela, Tari, Toppila-Salmi, Sanna, Bachert, Claus, Hellings, Peter W., Melén, Erik, Wickman, Magnus, Bindslev-Jensen, Carsten, Eller, Esben, O'Hehir, Robyn E., Cingi, Cemal, Gemicioğlu, Bilun, Kalayci, Omer, Ivancevich, Juan Carlos, and Bousquet, Jean

Abstract

BACKGROUND: Mobile technology may help to better understand the adherence to treatment MASK-rhinitis (Mobile Airways Sentinel NetworK for allergic rhinitis) is a patient-centered ICT system. A mobile phone app (the Allergy Diary) central to MASK is available in 22 countries. OBJECTIVES: To assess the adherence to treatment in allergic rhinitis patients using the Allergy Diary App. METHODS: An observational cross-sectional study was carried out on all users who filled in the Allergy Diary from January 1, 2016 to August 1, 2017. Secondary adherence was assessed by using the modified Medication Possession Ratio (MPR) and the Proportion of days covered (PDC) approach. RESULTS: 12,143 users were registered. 6,949 users reported at least one VAS data recording. Among them, 1,887 users reported ≥ 7 VAS data. 1,195 subjects were included in the analysis of adherence. 136 (11.28%) users were adherent (MPR ≥70% and PDC ≤ 1.25), 51 (4.23%) were partly adherent (MPR ≥70% and PDC =1.50) and 176 (14.60%) were switchers. On the other hand, 832 (69.05%) users were non-adherent to medications (MPR<70%). Of those, the largest group was non-adherent to medications and the time interval was increased in 442 (36.68%) users. CONCLUSION AND CLINICAL RELEVANCE: Adherence to treatment is low. The relative efficacy of continuous versus on-demand treatment for AR symptoms is still a matter of debate.This study shows an approach for measuring retrospective adherence based on a mobile app. This represent a novel approach also for analyzing medication taking behavior in a real-world setting. This article is protected by copyright. All rights reserved.

Published
2019
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30. The influence of lifestyle factors on constipation – should the pharmacist be aware of this?

Author

Minkutė, Rima, Andrijauskaitė, Indrė, Briedis, Vitalis, Minkutė, Rima, Andrijauskaitė, Indrė, and Briedis, Vitalis

Abstract

Aim of this study was to analyze the influence of lifestyle (nutrition and physical activity) on constipation and evaluate the respondents’ attitude to this disorder.Methods. Pharmacy visitors who agreed to answer questions were included in the study. Data from respondents based on age (18-45 years old; 46-65 years old; above 65 years old) and body mass index (“normal,” “overweight,” “obese”) was analyzed. Nutrition and physical activity were analyzed for the purpose of identifying risk factors for constipation. Descriptive and comparative statistics were used – the respondents’ responses are presented in frequencies and percentages, Chi-square test was executed to measure association with knowledge, responses and gender, age, BMI.Results. The study identified a 12.8 % constant constipation rate in the study group with no significant differences between genders, however more males had no constipation problem (50.5 % vs 39.9 %). The age and body mass index had association with constipation (p<0.05). The consumption of coffee and/or tea was not related to constipation in the study group, however, the respondents’ motionless lifestyle was related to constant and occasional constipation (75.0 % and 41.1 %, respectively) (p<0.05).Conclusions. The consumption of carbohydrates, inadequate intake of fluids and motionless lifestyle were identified as risk factors for constipation in this study. Lifestyle modification recommendations might be included in the pharmacists’ consultation, Целью этого исследования был анализ влияния образа жизни (питание и физических нагрузок) на запор и оценка отношения респондентов к этому расстройству.Методы. Посетители аптеки, которые согласились ответить на вопрос, были включены в исследование. Проанализированы данные респондентов на основе возраста (18-45 лет 46-65 лет старше 65 лет) и индекса массы тела ("нормально", "избыточный вес", "ожирение"). Питание и физические нагрузки были проанализированы с целью выявления факторов риска появления запора. Была использована описательная и сравнительная статистика - ответы респондентов представлены частотами и процентами, Хи-квадратный тест был выполнен для измерения ассоциации со знаниями, ответами и полом, возрастом, ИМТ.Результаты. В ходе исследования было установлено 12.8 % постоянной частоты запоров в исследуемой группе, независимо от пола, однако большинство мужчин не имели проблем с запорами (50.5 % против 39.9 %). Индекс массы тела и возраст был связан с запорами (р <0.05). Потребление кофе и / или чая не было связано с запорами в исследуемой группе, однако неподвижный образ жизни респондентов был связан с постоянными и случайными запорами (75.0 % и 41.1 %, соответственно) (р <0.05).Выводы. В этом исследовании были определены потребления углеводов, недостаточное потребление жидкости и неподвижный образ жизни как факторы риска развития запора. Рекомендации по изменению образа жизни могут быть включены в консультации провизоров., Метою цього дослідження був аналіз впливу способу життя (харчування та фізичних навантажень) на закреп та оцінка ставлення респондентів до цього розладу.Методи. Відвідувачі аптеки, які погодились відповісти на запитання, були включені у дослідження. Проаналізовано дані респондентів на основі віку (18-45 років; 46-65 років; старше 65 років) та індексу маси тіла ("нормально", "надмірна вага", "ожиріння"). Харчування та фізичні навантаження були проаналізовані з метою виявлення факторів ризику появи закрепу. Була використана описова та порівняльна статистика - відповіді респондентів представлені частотами та відсотками, Хі-квадратний тест був виконаний для вимірювання асоціації зі знаннями, відповідями та статтю, віком, ІМТ.Результати. У ході дослідження було встановлено 12.8 % постійної частоти закрепів в досліджуваній групі, незалежно від статі, проте більшість чоловіків не мали проблем із закрепами (50.5 % проти 39.9 %). Індекс маси тіла та вік був пов'язаний із закрепами (р <0.05). Споживання кави та / або чаю не було пов'язане із закрепами в досліджуваній групі, проте нерухомий спосіб життя респондентів був пов'язаний із постійними та випадковими закрепами (75.0 % та 41.1 %, відповідно) (р <0.05).Висновки. У цьому дослідженні були визначені споживання вуглеводів, недостатнє споживання рідини та нерухомий спосіб життя як фактори ризику розвитку закрепу. Рекомендації щодо зміни способу життя можуть бути включені до консультацій провізорів

Published
2019

31. Next-generation ARIA care pathways for rhinitis and asthma:a model for multimorbid chronic diseases

Author

Bousquet, J. Jean, Schünemann, Holger J., Togias, Alkis, Erhola, Marina, Hellings, Peter W., Zuberbier, Torsten, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bachert, Claus, Becker, Sven, Bedolla-Barajas, Martin, Bewick, Michael, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Boulet, Louis P., Bourrez, Jean Marc, Brusselle, Guy, Chavannes, Niels, Costa, Elisio, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Fokkens, Wytske J., Fonseca, Joao A., Gaga, Mina, Haahtela, Tari, Illario, Maddalena, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T.T., Larenas-Linnemann, Desiree, Laune, Daniel, Lourenço, Olga M., Menditto, Enrica, Mullol, Joaquin, Okamoto, Yashitaka, Papadopoulos, Nikos, Pham-Thi, Nhân, Picard, Robert, Pinnock, Hilary, Roche, Nicolas, Roller-Wirnsberger, Regina E., Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Vasankari, Tuula, Ventura, Maria Teresa, Walker, Samantha, Williams, Sian, Akdis, Cezmi A., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, Bateman, Eric, Bedbrook, Anna, Bennoor, K. S., Benveniste, Samuel, Bergmann, Karl C., Bialek, Slawomir, Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Mateo, Bonniaud, Philippe, Bouchard, Jacques, Briedis, Vitalis, Brightling, Christofer E., Brozek, Jan, Buhl, Roland, Buonaiuto, Roland, Canonica, Giorgo W., Cardona, Victoria, Carriazo, Ana M., Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., Chkhartishvili, Eka, Chu, Derek K., Cingi, Cemal, Colgan, Elaine, De Sousa, Jaime Correia, Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, Damato, Gennaro, Da Silva, Jane, Dantas, Carina, Dokic, Dejand, Dauvilliers, Yves, Dedeu, Antoni, De Feo, Giulia, Devillier, Philippe, Di Capua, Stefania, Dykewickz, Marc, Dubakiene, Ruta, Ebisawa, Motohiro, El-Gamal, Yaya, Eller, Esben, Emuzyte, Regina, Farrell, John, Fink-Wagner, Antjie, Fiocchi, Alessandro, Fontaine, Jean F., Gemicioǧlu, Bilun, Schmid-Grendelmeir, Peter, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria Antonieta, Hajjam, Jawad, O'Hourihane, John B., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Ivancevich, Juan C., Joos, Guy, Jung, Ki Suck, Jutel, Marek, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Mussa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, Leonardini, Lisa, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Marien, Gert, Mahboub, Bassam, Malva, Joao, Manning, Patrick, De Manuel Keenoy, Esteban, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Mathieu-Dupas, Eve, Matricardi, Poalo M., Melén, Eric, Melo-Gomes, Elisabete, Meltzer, Eli O., Mercier, Jacques, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Moda, Giuliana, Mogica-Martinez, Maria Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralf, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leila, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Novellino, Enrico, Nyembue, Dieudonné, O'Hehir, Robin, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle, Ouedraogo, Solange, Pali-Schöll, Isabella, Palkonen, Susanna, Panzner, Peter, Park, Hae Sim, Pépin, Jean Louis, Pereira, Ana Maria, Pfaar, Oliver, Paulino, Ema, Phillips, Jim, Plavec, Davor, Popov, Ted A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Pugin, Benoit, Raciborski, Filip, Rajabian-Söderlund, Rojin, Reitsma, Sietze, Rodo, Xavier, Romano, Antonino, Rosario, Nelson, Rottem, Menahenm, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sisul, Juan Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spranger, Otto, Stellato, Cristina, Stelmach, Rafael, Ulrik, Charlotte Suppli, Thibaudon, Michel, To, Teresa, Todo-Bom, Ana, Tomazic, Peter V., Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Van Der Kleij, Rianne, Vandenplas, Olivier, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Y., Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yorgancioglu, Arzu, Yusuf, Osman M., Zar, Heahter J., Zeng, Stéphane, Zernotti, Mario, Zhang, Luo, Zhong, Nan S., Zidarn, Mihaela, Bousquet, J. Jean, Schünemann, Holger J., Togias, Alkis, Erhola, Marina, Hellings, Peter W., Zuberbier, Torsten, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bachert, Claus, Becker, Sven, Bedolla-Barajas, Martin, Bewick, Michael, Bosnic-Anticevich, Sinthia, Bosse, Isabelle, Boulet, Louis P., Bourrez, Jean Marc, Brusselle, Guy, Chavannes, Niels, Costa, Elisio, Cruz, Alvaro A., Czarlewski, Wienczyslawa, Fokkens, Wytske J., Fonseca, Joao A., Gaga, Mina, Haahtela, Tari, Illario, Maddalena, Klimek, Ludger, Kuna, Piotr, Kvedariene, Violeta, Le, L. T.T., Larenas-Linnemann, Desiree, Laune, Daniel, Lourenço, Olga M., Menditto, Enrica, Mullol, Joaquin, Okamoto, Yashitaka, Papadopoulos, Nikos, Pham-Thi, Nhân, Picard, Robert, Pinnock, Hilary, Roche, Nicolas, Roller-Wirnsberger, Regina E., Rolland, Christine, Samolinski, Boleslaw, Sheikh, Aziz, Toppila-Salmi, Sanna, Tsiligianni, Ioanna, Valiulis, Arunas, Valovirta, Erkka, Vasankari, Tuula, Ventura, Maria Teresa, Walker, Samantha, Williams, Sian, Akdis, Cezmi A., Annesi-Maesano, Isabella, Arnavielhe, Sylvie, Basagana, Xavier, Bateman, Eric, Bedbrook, Anna, Bennoor, K. S., Benveniste, Samuel, Bergmann, Karl C., Bialek, Slawomir, Billo, Nils, Bindslev-Jensen, Carsten, Bjermer, Leif, Blain, Hubert, Bonini, Mateo, Bonniaud, Philippe, Bouchard, Jacques, Briedis, Vitalis, Brightling, Christofer E., Brozek, Jan, Buhl, Roland, Buonaiuto, Roland, Canonica, Giorgo W., Cardona, Victoria, Carriazo, Ana M., Carr, Warner, Cartier, Christine, Casale, Thomas, Cecchi, Lorenzo, Cepeda Sarabia, Alfonso M., Chkhartishvili, Eka, Chu, Derek K., Cingi, Cemal, Colgan, Elaine, De Sousa, Jaime Correia, Courbis, Anne Lise, Custovic, Adnan, Cvetkosvki, Biljana, Damato, Gennaro, Da Silva, Jane, Dantas, Carina, Dokic, Dejand, Dauvilliers, Yves, Dedeu, Antoni, De Feo, Giulia, Devillier, Philippe, Di Capua, Stefania, Dykewickz, Marc, Dubakiene, Ruta, Ebisawa, Motohiro, El-Gamal, Yaya, Eller, Esben, Emuzyte, Regina, Farrell, John, Fink-Wagner, Antjie, Fiocchi, Alessandro, Fontaine, Jean F., Gemicioǧlu, Bilun, Schmid-Grendelmeir, Peter, Gamkrelidze, Amiran, Garcia-Aymerich, Judith, Gomez, Maximiliano, Diaz, Sandra González, Gotua, Maia, Guldemond, Nick A., Guzmán, Maria Antonieta, Hajjam, Jawad, O'Hourihane, John B., Humbert, Marc, Iaccarino, Guido, Ierodiakonou, Despo, Ivancevich, Juan C., Joos, Guy, Jung, Ki Suck, Jutel, Marek, Kaidashev, Igor, Kalayci, Omer, Kardas, Przemyslaw, Keil, Thomas, Khaitov, Mussa, Khaltaev, Nikolai, Kleine-Tebbe, Jorg, Kowalski, Marek L., Kritikos, Vicky, Kull, Inger, Leonardini, Lisa, Lieberman, Philip, Lipworth, Brian, Lodrup Carlsen, Karin C., Loureiro, Claudia C., Louis, Renaud, Mair, Alpana, Marien, Gert, Mahboub, Bassam, Malva, Joao, Manning, Patrick, De Manuel Keenoy, Esteban, Marshall, Gailen D., Masjedi, Mohamed R., Maspero, Jorge F., Mathieu-Dupas, Eve, Matricardi, Poalo M., Melén, Eric, Melo-Gomes, Elisabete, Meltzer, Eli O., Mercier, Jacques, Miculinic, Neven, Mihaltan, Florin, Milenkovic, Branislava, Moda, Giuliana, Mogica-Martinez, Maria Dolores, Mohammad, Yousser, Montefort, Steve, Monti, Ricardo, Morais-Almeida, Mario, Mösges, Ralf, Münter, Lars, Muraro, Antonella, Murray, Ruth, Naclerio, Robert, Napoli, Luigi, Namazova-Baranova, Leila, Neffen, Hugo, Nekam, Kristoff, Neou, Angelo, Novellino, Enrico, Nyembue, Dieudonné, O'Hehir, Robin, Ohta, Ken, Okubo, Kimi, Onorato, Gabrielle, Ouedraogo, Solange, Pali-Schöll, Isabella, Palkonen, Susanna, Panzner, Peter, Park, Hae Sim, Pépin, Jean Louis, Pereira, Ana Maria, Pfaar, Oliver, Paulino, Ema, Phillips, Jim, Plavec, Davor, Popov, Ted A., Portejoie, Fabienne, Price, David, Prokopakis, Emmanuel P., Pugin, Benoit, Raciborski, Filip, Rajabian-Söderlund, Rojin, Reitsma, Sietze, Rodo, Xavier, Romano, Antonino, Rosario, Nelson, Rottem, Menahenm, Ryan, Dermot, Salimäki, Johanna, Sanchez-Borges, Mario M., Sisul, Juan Carlos, Solé, Dirceu, Somekh, David, Sooronbaev, Talant, Sova, Milan, Spranger, Otto, Stellato, Cristina, Stelmach, Rafael, Ulrik, Charlotte Suppli, Thibaudon, Michel, To, Teresa, Todo-Bom, Ana, Tomazic, Peter V., Valero, Antonio A., Valenta, Rudolph, Valentin-Rostan, Marylin, Van Der Kleij, Rianne, Vandenplas, Olivier, Vezzani, Giorgio, Viart, Frédéric, Viegi, Giovanni, Wallace, Dana, Wagenmann, Martin, Wang, De Y., Waserman, Susan, Wickman, Magnus, Williams, Dennis M., Wong, Gary, Wroczynski, Piotr, Yiallouros, Panayiotis K., Yorgancioglu, Arzu, Yusuf, Osman M., Zar, Heahter J., Zeng, Stéphane, Zernotti, Mario, Zhang, Luo, Zhong, Nan S., and Zidarn, Mihaela

Abstract

Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhi-nitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted "patient activation", (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement.

Published
2019

32. ARIA pharmacy 2018 Allergic rhinitis care pathways for community pharmacy AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Sante) \nPOLLAR (Impact of Air POLLution on Asthma and Rhinitis)\nGARD Demonstration project

Author

Bosnic-Anticevich, Sinthia, Costa, Elisio, Menditto, Enrica, Lourenco, Olga, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Buonaiuto, Roland, Chrystyn, Henry, Cvetkovski, Biljana, Di Capua, Stefania, Kritikos, Vicky, Mair, Alpana, Orlando, Valentina, Paulino, Ema, Salimaki, Johanna, Soderlund, Rojin, Tan, Rachel, Williams, Dennis M., Wroczynski, Piotr, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bedbrook, Anna, Bachert, Claus, Bewick, Mike, Bindslev-Jensen, Carsten, Brozek, Jan L., Canonica, Giorgio Walter, Cardona, Victoria, Carr, Warner, Casale, Thomas B., Chavannes, Niels H., de Sousa, Jaime Correia, Cruz, Alvaro A., Czarlewski, Wienczyslawa, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Philippe, Dykewicz, Mark S., Gaga, Mina, El-Gamal, Yehia, Fonseca, Joao, Fokkens, Wytske J., Antonieta Guzman, Maria, Haahtela, Tari, Hellings, Peter W., Illario, Maddalena, Carlos Ivancevich, Juan, Just, Jocelyne, Kaidashev, Igor, Khaitov, Musa, Khaltaev, Nikolai, Keil, Thomas, Klimek, Ludger, Kowalski, Marek L., Kuna, Piotr, Kvedariene, Violeta, Larenas-Linnemann, Desiree E., Laune, Daniel, Le, Lan T. T., Carlsen, Karin C. Lodrup, Mahboub, Bassam, Maier, Dieter, Malva, Joao, Manning, Patrick J., Morais-Almeida, Mario, Moesges, Ralph, Mullol, Joaquim, Munter, Lars, Murray, Ruth, Naclerio, Robert, Nannazova-Baranove, Leyla, Nekann, Kristof, Nyembue, Tshipukane Dieudonne, Okubo, Kimi, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L., Palkonen, Susanna, Panzner, Petr, Papadopoulos, Nikolaos G., Park, Hae-Sim, Pawankar, Ruby, Pfaar, Oliver, Phillips, Jim, Plavec, Davor, Popov, Todor A., Potter, Paul C., Prokopakis, Emmanuel P., Roller-Wirnsberger, Regina E., Rottenn, Menachem, Ryan, Dermot, Sannolinski, Bolesfaw, Sanchez-Borges, Mario, Schunemann, Holger J., Sheikh, Aziz, Sisul, Juan Carlos, Somekh, David, Stellato, Cristiana, To, Teresa, Todo-Bonn, Ana Maria, Tonnazic, Peter Valentin, Toppila-Salmi, Sanna, Valero, Antonio, Valiulis, Arunas, Valovirta, Errka, Ventura, Maria Teresa, Wagennnann, Martin, Wallace, Dana, Wasernnan, Susan, Wickman, Magnus, Yiallouros, Panayiotis K., Yorgancioglu, Arzu, Yusuf, Osman M., Zar, Heather J., Zernotti, Mario E., Zhang, Luo, Zidarn, Mihaela, Zuberbier, Torsten, Bousquet, Jean, Bosnic-Anticevich, Sinthia, Costa, Elisio, Menditto, Enrica, Lourenco, Olga, Novellino, Ettore, Bialek, Slawomir, Briedis, Vitalis, Buonaiuto, Roland, Chrystyn, Henry, Cvetkovski, Biljana, Di Capua, Stefania, Kritikos, Vicky, Mair, Alpana, Orlando, Valentina, Paulino, Ema, Salimaki, Johanna, Soderlund, Rojin, Tan, Rachel, Williams, Dennis M., Wroczynski, Piotr, Agache, Ioana, Ansotegui, Ignacio J., Anto, Josep M., Bedbrook, Anna, Bachert, Claus, Bewick, Mike, Bindslev-Jensen, Carsten, Brozek, Jan L., Canonica, Giorgio Walter, Cardona, Victoria, Carr, Warner, Casale, Thomas B., Chavannes, Niels H., de Sousa, Jaime Correia, Cruz, Alvaro A., Czarlewski, Wienczyslawa, De Carlo, Giuseppe, Demoly, Pascal, Devillier, Philippe, Dykewicz, Mark S., Gaga, Mina, El-Gamal, Yehia, Fonseca, Joao, Fokkens, Wytske J., Antonieta Guzman, Maria, Haahtela, Tari, Hellings, Peter W., Illario, Maddalena, Carlos Ivancevich, Juan, Just, Jocelyne, Kaidashev, Igor, Khaitov, Musa, Khaltaev, Nikolai, Keil, Thomas, Klimek, Ludger, Kowalski, Marek L., Kuna, Piotr, Kvedariene, Violeta, Larenas-Linnemann, Desiree E., Laune, Daniel, Le, Lan T. T., Carlsen, Karin C. Lodrup, Mahboub, Bassam, Maier, Dieter, Malva, Joao, Manning, Patrick J., Morais-Almeida, Mario, Moesges, Ralph, Mullol, Joaquim, Munter, Lars, Murray, Ruth, Naclerio, Robert, Nannazova-Baranove, Leyla, Nekann, Kristof, Nyembue, Tshipukane Dieudonne, Okubo, Kimi, O'Hehir, Robyn E., Ohta, Ken, Okamoto, Yoshitaka, Onorato, Gabrielle L., Palkonen, Susanna, Panzner, Petr, Papadopoulos, Nikolaos G., Park, Hae-Sim, Pawankar, Ruby, Pfaar, Oliver, Phillips, Jim, Plavec, Davor, Popov, Todor A., Potter, Paul C., Prokopakis, Emmanuel P., Roller-Wirnsberger, Regina E., Rottenn, Menachem, Ryan, Dermot, Sannolinski, Bolesfaw, Sanchez-Borges, Mario, Schunemann, Holger J., Sheikh, Aziz, Sisul, Juan Carlos, Somekh, David, Stellato, Cristiana, To, Teresa, Todo-Bonn, Ana Maria, Tonnazic, Peter Valentin, Toppila-Salmi, Sanna, Valero, Antonio, Valiulis, Arunas, Valovirta, Errka, Ventura, Maria Teresa, Wagennnann, Martin, Wallace, Dana, Wasernnan, Susan, Wickman, Magnus, Yiallouros, Panayiotis K., Yorgancioglu, Arzu, Yusuf, Osman M., Zar, Heather J., Zernotti, Mario E., Zhang, Luo, Zidarn, Mihaela, Zuberbier, Torsten, and Bousquet, Jean

Abstract

Pharmacists are trusted health care professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide optimal advice/interventions/strategies to patients with rhinitis. The Allergic Rhinitis and its Impact on Asthma (ARIA)-pharmacy ICP includes a diagnostic questionnaire specifically focusing attention on key symptoms and markers of the disease, a systematic Diagnosis Guide (including differential diagnoses), and a simple flowchart with proposed treatment for rhinitis and asthma multimorbidity. Key prompts for referral within the ICP are included. The use of technology is critical to enhance the management of allergic rhinitis. However, the ARIA-pharmacy ICP should be adapted to local healthcare environments/situations as regional (national) differences exist in pharmacy care.

Published
2019

34. ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”

Author

Bosnic‐Anticevich, Sinthia, primary, Costa, Elisio, additional, Menditto, Enrica, additional, Lourenço, Olga, additional, Novellino, Ettore, additional, Bialek, Slawomir, additional, Briedis, Vitalis, additional, Buonaiuto, Roland, additional, Chrystyn, Henry, additional, Cvetkovski, Biljana, additional, Di Capua, Stefania, additional, Kritikos, Vicky, additional, Mair, Alpana, additional, Orlando, Valentina, additional, Paulino, Ema, additional, Salimäki, Johanna, additional, Söderlund, Rojin, additional, Tan, Rachel, additional, Williams, Dennis M., additional, Wroczynski, Piotr, additional, Agache, Ioana, additional, Ansotegui, Ignacio J., additional, Anto, Josep M., additional, Bedbrook, Anna, additional, Bachert, Claus, additional, Bewick, Mike, additional, Bindslev‐Jensen, Carsten, additional, Brozek, Jan L., additional, Canonica, Giorgio Walter, additional, Cardona, Victoria, additional, Carr, Warner, additional, Casale, Thomas B., additional, Chavannes, Niels H., additional, Correia de Sousa, Jaime, additional, Cruz, Alvaro A., additional, Czarlewski, Wienczyslawa, additional, De Carlo, Giuseppe, additional, Demoly, Pascal, additional, Devillier, Philippe, additional, Dykewicz, Mark S., additional, Gaga, Mina, additional, El‐Gamal, Yehia, additional, Fonseca, João, additional, Fokkens, Wytske J., additional, Guzmán, Maria Antonieta, additional, Haahtela, Tari, additional, Hellings, Peter W., additional, Illario, Maddalena, additional, Ivancevich, Juan Carlos, additional, Just, Jocelyne, additional, Kaidashev, Igor, additional, Khaitov, Musa, additional, Khaltaev, Nikolai, additional, Keil, Thomas, additional, Klimek, Ludger, additional, Kowalski, Marek L., additional, Kuna, Piotr, additional, Kvedariene, Violeta, additional, Larenas‐Linnemann, Désirée E., additional, Laune, Daniel, additional, Le, Lan T. T., additional, Lodrup Carlsen, Karin C., additional, Mahboub, Bassam, additional, Maier, Dieter, additional, Malva, Joao, additional, Manning, Patrick J., additional, Morais‐Almeida, Mário, additional, Mösges, Ralph, additional, Mullol, Joaquim, additional, Münter, Lars, additional, Murray, Ruth, additional, Naclerio, Robert, additional, Namazova‐Baranova, Leyla, additional, Nekam, Kristof, additional, Nyembue, Tshipukane Dieudonné, additional, Okubo, Kimi, additional, O'Hehir, Robyn E., additional, Ohta, Ken, additional, Okamoto, Yoshitaka, additional, Onorato, Gabrielle L., additional, Palkonen, Susanna, additional, Panzner, Petr, additional, Papadopoulos, Nikolaos G., additional, Park, Hae‐Sim, additional, Pawankar, Ruby, additional, Pfaar, Oliver, additional, Phillips, Jim, additional, Plavec, Davor, additional, Popov, Todor A., additional, Potter, Paul C., additional, Prokopakis, Emmanuel P., additional, Roller‐Wirnsberger, Regina E., additional, Rottem, Menachem, additional, Ryan, Dermot, additional, Samolinski, Bolesław, additional, Sanchez‐Borges, Mario, additional, Schunemann, Holger J., additional, Sheikh, Aziz, additional, Sisul, Juan Carlos, additional, Somekh, David, additional, Stellato, Cristiana, additional, To, Teresa, additional, Todo‐Bom, Ana Maria, additional, Tomazic, Peter Valentin, additional, Toppila‐Salmi, Sanna, additional, Valero, Antonio, additional, Valiulis, Arunas, additional, Valovirta, Errka, additional, Ventura, Maria Teresa, additional, Wagenmann, Martin, additional, Wallace, Dana, additional, Waserman, Susan, additional, Wickman, Magnus, additional, Yiallouros, Panayiotis K., additional, Yorgancioglu, Arzu, additional, Yusuf, Osman M., additional, Zar, Heather J., additional, Zernotti, Mario E., additional, Zhang, Luo, additional, Zidarn, Mihaela, additional, Zuberbier, Torsten, additional, and Bousquet, Jean, additional

Published
2019
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36. Formation and investigation of electrospun PLA materials with propolis extracts and silver nanoparticles for biomedical applications

Author

Adomavičiūtė, Erika, Pupkevičiūtė, Solveiga, Juškaitė, Vaida, Žilius, Modestas, Stanys, Sigitas, Pavilonis, Alvydas, Briedis, Vitalis, and Hindawi Publishing Corporation

Subjects
Silver| pharmacology, Coated materials, biocompatible| pharmacology, Silver| chemistry, Anti-bacterial agents| chemistry, technology, industry, and agriculture, Propolis| chemistry, Anti-bacterial agents| pharmacology, Wound healing| drug effects, Propolis| pharmacology
Abstract

An electrospun hydrophilic non-water-soluble biocompatible polylactic acid (PLA) nonwoven material was used as a delivery system for propolis ethanolic extract (PEE) and silver nanoparticles (AgNPs) that are known for their established antiseptic and antimicrobial activity. Combination of PEE and AgNPs in a single product should provide efficient antimicrobial protection and improved wound healing. Evaluations of PEE and AgNPs on morphology of electrospun materials, release kinetics of AgNPs and phenolic compounds, antibacterial properties, and cytotoxicity of electrospun PLAmaterials were performed. The presence of PEE or/and AgNPs resulted in densermats formed by thicker PLA fibers.Theaverage diameter of PLA microfibers was 168±29 nm.The average diameter of microfibers increased to 318 ± 40 and 370 ± 30nm when 10 wt% and 20 wt% ethanol were added, respectively. Addition of 10wt% or 20wt% PEE increased the diameter to 282 ± 25 and 371 ± 25 nm, respectively. Suspension of AgNPs also caused the formation of thicker microfibers with 254±25nm diameter. Electrospun PLA microfibers with PEE maintained viability of HaCaT cells. Testing of antimicrobial activity confirmed the ability of AgNPs containing PLA electrospun materials to inhibit the growth of microorganisms.

Published
2017

37. Release of milk Thistle (Silybum Marianum L.) extract compounents from semisolid formulations and their penetration into human skin

Author

Politaitė, Aušrinė, Žilius, Modestas, and Briedis, Vitalis

Subjects
615.322 [udc], Milk Thistle, chemistry, Plant extracts, analysis, Skin absorption, physiology, Skin, metabolism
Abstract

The purposeful development of semisolid formulations should provide the efficient release of biologically active compounds and their transdermal delivery into human skin. Silymarin is the dry extract produced from the dried fruits of milk thistle (Silybum marianum L.) and containing flavonoid taxifolin and flavonolignans such as silychristin, silydianin, silybin (A and B) and isosilybin (A and B). This extract demonstrates antioxidant, anti-inflammatory activities [1]. The aim of this study was to evaluate the release of milk thistle extract active compounds (taxifolin, silychristin, silibin A and B) from experimental semisolid formulations and their penetration into the human skin layers ex vivo. Emulsion creams (w/o), poloxomer based gelified cream and hydrogel, each of them containing silymarin in 2-hydroxypropyl-β-cyclodextrin 4% aqueous solution, and poloxomer based gelified cream containing silymarin in labrasol 30% aqueous solution. All w/o creams and gelified creams contained 10% of oleic acid as penetration enhancer. Formulations were characterized by pH and viscosity. In vitro release studies were performed at 32±0.5°C using modified Franz type diffusion cells. Ex vivo skin permeation studies were conducted using Bronaugh type flow-through diffusion cells with full-thickness human skin. The samples were analysed by validated HPLC method. The pH of the semisolid formulations was within the range 4.67–6.65. The viscosity of formulations at 32°C temperature was within the range from 27.9±1.1 to 554.0±8.7 Pa·s. The release kinetics of silymarin compounds conformed to zero order model (r2=0.9713–0.9966). The highest amount of silymarin compounds (120.0±8.6 μg/cm²) in 5 hours was released from hydrogel containing 25% of poloxamer 407. The results of penetration study showed poor skin penetration of silymarin compounds. Only 0.80±0.46 μg/cm² of silychistin penetrated into derma after application

Published
2017

47. Formation and characterization of melt-spun polypropylene fibers with propolis for medical applications.

Author

Adomavičiūtė, Erika, Baltušnikaitė-Guzaitienė, Julija, Juškaitė, Vaida, Žilius, Modestas, Briedis, Vitalis, and Stanys, Sigitas

Subjects
SPUN yarns, POLYPROPYLENE, PROPOLIS, MEDICAL applications of composite materials, CELL-mediated cytotoxicity
Abstract

The search of possibilities to improve the functional properties of textile materials has been continuing for years with the aim to provide higher hygiene characteristics offer advanced therapeutic functionality. One of available approaches to provide new properties for textiles is the inclusion of natural ingredients. Propolis extracts are successfully used in practical therapeutics for accelerated wound healing and cell proliferation processes. In this study, pure multi-filament yarns and yarns saturated with propolis were developed and characterized. The effect of preparation and formulation parameters on the characteristics of yarns was evaluated; the release of propolis extract components from yarns and their possible cytotoxicity on cell formation was also determined. [ABSTRACT FROM PUBLISHER]

Published
2018
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48. Propolio ekstrakto komponentų atsipalaidavimo iš emulsinių dispersijų tyrimai

Author

Ramanauskienė, Kristina, Žilius, Modestas, and Briedis, Vitalis

Subjects
Propolis, Chemistry, Emulsions, Drug stability, Anti-infective agents, Delayed-action preparations, Drug carriers, food and beverages, 615.324:368.1 [udc]
Abstract

Background and Objective. Carrier development is one of the essential stages in the formulation of semisolid pharmaceutical dosage form for topical application. The stability of semisolid preparation during storage can be predicted from rheological testing. An adequate composition of semisolid preparation determines its stability and proper release of drug substance, and allows bypassing long-term heating and melting of the cream base components while incorporating complex extracts. Soft propolis extract, well known for its antimicrobial, antiviral, anti-infl ammatory, and antioxidant effects, was chosen as a complex biologically active ingredient for the development of emulsion dispersion system. The aim of this study was to evaluate the impact of physical-chemical characteristics of the carrier on the release rate of biologically active ingredients from the modeled dosage form in vitro, thus justifying the relevance of the carrier composition and applied technologies. Material and Methods. Soft propolis extract (1%–3%) was incorporated into water-in-oil type emulsion. The quality of the model systems was evaluated referring to their viscosity, quantity of polyphenols and their rate of release from the preparation by applying an in vitro model. Quantitative determination of polyphenols was performed by spectrophotometry using a standard calibration curve of ferulic acid. Results. The results showed that a stable homogeneous semisolid emulsion system containing soft propolis extract could be produced when the concentration of emulsifi er was in the range of 3%–12%. The quantity of emulsifi er had an impact on the viscosity of semisolid systems, but practically had no effect on the release rate of polyphenols from the cream matrix. The results also demonstrated that the added amount of soft propolis extract had a less signifi cant effect than temperature of the system.[...].

Published
2011

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