Search

This bachelor thesis discusses the effects of tolytoxin and its structural variant 7 O methylscytophycin B from the scytophycin family of macrolides on cancer and primary cell lines. The two main goals of this study was to compare the chemical structure and the effects of both toxins on cancer and primary cell lines and whether the cells treated by these agents go through regulated cell death, specifically the intrinsic pathway of apoptosis. In the last chapter, the potential use of these toxins in future cancer research and clinical use are discussed.

This Master thesis focuses mainly on the efficiency of supporting small and medium enterprises in the Czech Republic. Small and medium business promotion creates one of the main targets of the European Union policy. A lot of research has been conducted in the area of business support. This thesis will subsequently analyze practical aspects of the promotion and it captures both programme periods by the year 2013. Very interesting and to certain extent crucial for this work are changes in Union allowance of smaller firms. The aim of the study is to suggest possible measures and recommendations in the area of economic policy and business promotion system that could help solve the current situation.