1. The physical maps for sequencing human chromosomes 1, 6, 9, 10, 13, 20 and X.
- Author
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Bentley, D.R., Deloukas, P., Dunham, A., French, L., Gregory, S.G., Humphray, S.J., Mungall, A.J., Ross, M.T., Carter, N.P., Dunham, I., Scott, C.E., Ashcroft, K.J., Atkinson, A.L., Aubin, K., Beare, D.M., Bethel, G., Brady, N., Brook, J.C., Burford, D.C., and Burrill, W. D.
- Subjects
GENE mapping ,GENETIC techniques ,CHROMOSOME analysis ,CLONING - Abstract
Reports the construction of maps for chromosomes 1, 6, 9, 10, 13, 20, and X, by building landmark maps, isolating bacterial clones and assembling contigs. Ability to establish the long-range organization of the maps early in the project using this approach; Simplification of contig extension, gap closure, and problem-solving with this method because of containment within local regions; Percentage of the euchromatic regions and chromosome-specific markers in the human gene map which these represent; Applications for assessing sequenced clones.
- Published
- 2001
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