Search

Your search keyword '"Brown, Angela L."' showing total 27 results
Start Over Author "Brown, Angela L."
27 results on '"Brown, Angela L."'

1. High rates of undiagnosed and uncontrolled hypertension upon a screening campaign in rural Rwanda: a cross-sectional study

Author

Ntaganda, Evariste, Mugeni, Regine, Harerimana, Emmanuel, Ngoga, Gedeon, Dusabeyezu, Symaque, Uwinkindi, Francois, Utumatwishima, Jean N., Mutimura, Eugene, Davila-Roman, Victor G., Schechtman, Kenneth, Nishimwe, Aurore, Twizeyimana, Laurence, Brown, Angela L., Cade, W. Todd, Bushaku, Marcus, de Las Fuentes, Lisa, Reeds, Dominic, and Twagirumukiza, Marc

Published
2022
Full Text
View/download PDF

2. Renal Denervation for the Treatment of Hypertension: A Scientific Statement From the American Heart Association.

Author

Cluett, Jennifer L., Blazek, Olivia, Brown, Angela L., East, Cara, Ferdinand, Keith C., Fisher, Naomi D. L., Ford, Cassandra D., Griffin, Karen A., Mena-Hurtado, Carlos I., Sarathy, Harini, Vongpatanasin, Wanpen, and Townsend, Raymond R.

Abstract

Hypertension is a leading risk factor for cardiovascular morbidity and mortality. Despite the widespread availability of both pharmacological and lifestyle therapeutic options, blood pressure control rates across the globe are worsening. In fact, only 23% of individuals with high blood pressure in the United States achieve treatment goals. In 2023, the US Food and Drug Administration approved renal denervation, a catheter-based procedure that ablates the renal sympathetic nerves, as an adjunctive treatment for patients in whom lifestyle modifications and antihypertensive medications do not adequately control blood pressure. This approval followed the publication of multiple randomized clinical studies using rigorous trial designs, all incorporating renal angiogram as the sham control. Most but not all of the new generation of trials reached their primary end point, demonstrating modest efficacy of renal denervation in lowering blood pressure across a spectrum of hypertension, from mild to truly resistant. Individual patient responses vary, and further research is needed to identify those who may benefit most. The initial safety profile appears favorable, and multiple ongoing studies are assessing longer-term efficacy and safety. Multidisciplinary teams that include hypertension specialists and adequately trained proceduralists are crucial to ensure that referrals are made appropriately with full consideration of the potential risks and benefits. Incorporating patient preferences and engaging in shared decision-making conversations will help patients make the best decisions given their individual circumstances. Although further research is clearly needed, renal denervation presents a novel treatment strategy for patients with uncontrolled blood pressure. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

3. Religiously Involved Black Male Engagement at Religiously Affiliated Predominately White Institutions

Author

Brown, Angela L.

Abstract

Research studies have indicated that Black male collegians have the lowest retention rates in the higher education setting in predominately White institutional (PWI) settings. Several factors, such as spirituality, involvement on campus, and other positive experiences are cited as contributing to a lower retention rate for Black males in the PWI higher education setting; however, research in the PWI religiously affiliated setting has been limited. The purpose of this basic qualitative study was to explore the campus engagement experiences of religiously involved Black males who attended religiously affiliated PWIs. Astin's student involvement theory and Astin, Astin, and Lindholm's findings on spiritual development in the higher education setting are used as a conceptual framework. The research questions explored how religiously involved Black males who were at religiously affiliated PWIs during college described their campus engagement experiences, how their religious belief influenced their campus engagement, and how other factors influenced their campus engagement and contributed to their graduation. Interviews with 8 Black male participants were analyzed for codes and themes using Merriam and Tisdell's coding method. The themes that emerged suggested that although participants perceived initial negative experiences, overall, they had positive campus experiences due to involvement experiences. The participants recalled that their religious engagement fostered more participation in religious involvement, developed their spiritual identity, and that family and community fostered engagement. This study may contribute to positive social change by providing administrators of religiously affiliated PWIs with approaches to increase the engagement and retention of Black male students. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]

Published
2018

5. Contributors

Author

Abel, E. Dale, primary, Adamo, Luigi, additional, Ali, Shah R., additional, Allen, Larry A., additional, Bakris, George L., additional, Bloomfield, Gerald S., additional, Bonow, Robert O., additional, Bozkurt, Biykem, additional, Bristow, Michael R., additional, Brown, Angela L., additional, Bugger, Heiko, additional, Burnett, John C., additional, Butler, Javed, additional, Carroll, John D., additional, Castaño, Adam, additional, Chang, Anna Marie, additional, Cohn, Jay N., additional, Colucci, Wilson S., additional, Dell’Italia, Louis J., additional, Deswal, Anita, additional, DeVore, Adam D., additional, Diwan, Abhinav, additional, DuBrock, Hilary M., additional, Dunlay, Shannon M., additional, Dzhoyashvili, Nina, additional, Ewald, Gregory A., additional, Ezekowitz, Justin A., additional, Fang, James C., additional, Fedson, Savitri, additional, Feinstein, Matthew J., additional, Felker, G. Michael, additional, Ferguson, John D., additional, Ferrari, Victor A., additional, Ferrario, Carlos M., additional, Flaherty, James D., additional, Floras, John S., additional, Florea, Viorel G., additional, Gaggin, Hanna K., additional, Greenberg, Barry, additional, Hare, Joshua M., additional, Hernandez, Adrian F., additional, Hill, Joseph A., additional, Ibrahim, Nasrien E., additional, Januzzi, James L., additional, Joseph, Susan M., additional, Judge, Daniel P., additional, Kahn, Andrew M., additional, Kalogeropoulos, Andreas P., additional, Kass, David A., additional, Keaney, John, additional, Khan, Ahsan A., additional, Kim, Paul J., additional, Kobashigawa, Jon A., additional, Kransdorf, Evan P., additional, Krieger, Eric V., additional, Lam, Nicholas T., additional, Lenihan, Daniel J., additional, Lip, Gregory Y.H., additional, Longenecker, Chris T., additional, MacLellan, W. Robb, additional, Mann, Douglas L., additional, Marian, Ali J., additional, Matlock, Daniel D., additional, Maurer, Mathew S., additional, McNamara, Dennis M., additional, Mentz, Robert J., additional, Metra, Marco, additional, Milano, Carmelo A., additional, Misra, Arunima, additional, Mitchell, Joshua D., additional, Morrison, Alan R., additional, Nabeebaccus, Adam, additional, Nakamura, Kenta, additional, Nativi-Nicolau, Jose, additional, Ngo, Doan T.M., additional, Oatmen, Kelsie E., additional, Pang, Peter S., additional, Papadimitriou, Lampros, additional, Paulus, Walter J., additional, Polonsky, Tamar S., additional, Port, J. David, additional, Rader, Florian, additional, Ragupathi, Loheetha, additional, Redfield, Margaret M., additional, Rich, Michael W., additional, Rogers, Joseph G., additional, Ryan, John J., additional, Sadek, Hesham A., additional, Sag, Can Martin, additional, Sapp, Ashley A., additional, Sawyer, Douglas B., additional, Schulze, P. Christian, additional, Shah, Ajay M., additional, Shantsila, Eduard, additional, Singh, Jagmeet P., additional, Sinusas, Albert J., additional, Sliwa, Karen, additional, Spinale, Francis G., additional, Stewart, Simon, additional, Sucharov, Carmen, additional, John Sutton, Martin St., additional, Sverdlov, Aaron L., additional, Toth, Michael J., additional, Valente, Anne Marie, additional, van Heerebeek, Loek, additional, Varagic, Jasmina, additional, Victor, Ronald G., additional, Webb, Ian, additional, Wende, Adam R., additional, Whellan, David, additional, and Wiktor, Dominik M., additional

Published
2020
Full Text
View/download PDF

7. The Effect of Interventions to Prevent Type 2 Diabetes on the Development of Diabetic Retinopathy: The DPP/DPPOS Experience

Author

White, Neil H., Pan, Qing, Knowler, William C., Schroeder, Emily B., Dabelea, Dana, Chew, Emily Y., Blodi, Barbara, Goldberg, Ronald B., Pi-Sunyer, Xavier, Darwin, Christine, Schlögl, Mathias, Nathan, David M., Goldstein, Barry J., Furlong, Kevin, Smith, Kellie A., Mendoza, Jewel, Wildman, Wendi, Simmons, Marsha, Jensen, Genine, Liberoni, Renee, Spandorfer, John, Pepe, Constance, Donahue, Richard P., Prineas, Ronald, Rowe, Patricia, Giannella, Anna, Calles, Jeanette, Sanguily, Juliet, Cassanova-Romero, Paul, Castillo-Florez, Sumaya, Florez, Hermes J., Garg, Rajesh, Kirby, Lascelles, Lara, Olga, Larreal, Carmen, McLymont, Valerie, Mendez, Jadell, Perry, Arlette, Saab, Patrice, Veciana, Bertha, Haffner, Steven M., Hazuda, Helen P., Montez, Maria G., Isaac, Juan, Hattaway, Kathy, Lorenzo, Carlos, Martinez, Arlene, Salazar, Monica, Walker, Tatiana, Hamman, Richard F., Nash, Patricia V., Steinke, Sheila C., Testaverde, Lisa, Truong, Jennifer, Anderson, Denise R., Ballonoff, Larry B., Bouffard, Alexis, Boxer, Rebecca S., Bucca, Brian, Calonge, B. Ned, Delve, Lynne, Farago, Martha, Hill, James O., Hoyer, Shelley R., Jenkins, Tonya, Jortberg, Bonnie T., Lenz, Dione, Miller, Marsha, Nilan, Thomas, Perreault, Leigh, Price, David W., Regensteiner, Judith G., Seagle, Helen, Smith, Carissa M., VanDorsten, Brent, Horton, Edward S., Munshi, Medha, Lawton, Kathleen E., Poirier, Catherine S., Swift, Kati, Jackson, Sharon D., Arky, Ronald A., Bryant, Marybeth, Burke, Jacqueline P., Caballero, Enrique, Callaphan, Karen M., Fargnoli, Barbara, Franklin, Therese, Ganda, Om P., Guidi, Ashley, Guido, Mathew, Jacobsen, Alan M., Kula, Lyn M., Kocal, Margaret, Lambert, Lori, Ledbury, Sarah, Malloy, Maureen A., Middelbeek, Roeland J.W., Nicosia, Maryanne, Oldmixon, Cathryn F., Pan, Jocelyn, Quitingon, Marizel, Rainville, Riley, Rubtchinsky, Stacy, Seely, Ellen W., Sansoucy, Jessica, Schweizer, Dana, Simonson, Donald, Smith, Fannie, Solomon, Caren G., Spellman, Jeanne, Warram, James, Kahn, Steven E., Montgomery, Brenda K., Fattaleh, Basma, Colegrove, Celeste, Fujimoto, Wilfred, Knopp, Robert H., Lipkin, Edward W., Marr, Michelle, Morgan-Taggart, Ivy, Murillo, Anne, O’Neal, Kayla, Trence, Dace, Taylor, Lonnese, Thomas, April, Tsai, Elaine C., Kitabchi, Abbas E., Dagogo-Jack, Samuel, Murphy, Mary E., Taylor, Laura, Dolgoff, Jennifer, Hampton, Ethel Faye, Applegate, William B., Bryer-Ash, Michael, Clark, Debra, Frieson, Sandra L., Ibebuogu, Uzoma, Imseis, Raed, Lambeth, Helen, Lichtermann, Lynne C., Oktaei, Hooman, Ricks, Harriet, Rutledge, Lily M.K., Sherman, Amy R., Smith, Clara M., Soberman, Judith E., Williamsleaves, Beverly, Patel, Avnisha, Nyenwe, Ebenezer A., Metzger, Boyd E., Molitch, Mark E., Wallia, Amisha, Johnson, Mariana K., VanderMolen, Sarah, Adelman, Daphne T., Behrends, Catherine, Cook, Michelle, Fitzgibbon, Marian, Giles, Mimi M., Hartmuller, Monica, Johnson, Cheryl K.H., Larsen, Diane, Lowe, Anne, Lyman, Megan, McPherson, David, Penn, Samsam C., Pitts, Thomas, Reinhart, Renee, Roston, Susan, Schinleber, Pamela A., McKitrick, Charles, Turgeon, Heather, Larkin, Mary, Mugford, Marielle, Thangthaeng, Nopporn, Leander, Fernelle, Abbott, Kathy, Anderson, Ellen, Bissett, Laurie, Bondi, Kristy, Cagliero, Enrico, Florez, Jose C., Delahanty, Linda, Goldman, Valerie, Grassa, Elaine, Gurry, Lindsey, D’Anna, Kali, Leandre, Fernelle, Lou, Peter, Poulos, Alexandra, Raymond, Elyse, Ripley, Valerie, Stevens, Christine, Tseng, Beverly, Olefsky, Jerrold M., Barrettonnor, Elizabeth, Mudaliar, Sunder, Rosario Araneta, Maria, Carrion-Petersen, Mary Lou, Vejvoda, Karen, Bassiouni, Sarah, Beltran, Madeline, Claravall, Lauren N., Dowden, Jonalle M., Edelman, Steven V., Garimella, Pranav, Henry, Robert R., Horne, Javiva, Lamkin, Marycie, Szerdi Janesch, Simona, Leos, Diana, Polonsky, William, Ruiz, Rosa, Smith, Jean, Torio-Hurley, Jennifer, Pi-Sunyer, F. Xavier, Laferrere, Blandine, Lee, Jane E., Hagamen, Susan, Kelly-Dinham, Kim, Allison, David B., Agharanya, Nnenna, Aronoff, Nancy J., Baldo, Maria, Crandall, Jill P., Foo, Sandra T., Luchsinger, Jose A., Pal, Carmen, Parkes, Kathy, Pena, Mary Beth, Roman, Julie, Rooney, Ellen S., VanWye, Gretchen E.H., Viscovich, Kristine A., Prince, Melvin J., Marrero, David G., Mather, Kieren J., De Groot, Mary, Kelly, Susie M., Jackson, Marcia A., McAtee, Gina, Putenney, Paula, Ackermann, Ronald T., Cantrell, Carolyn M., Dotson, Yolanda F., Fineberg, Edwin S., Fultz, Megan, Guare, John C., Hadden, Angela, Ignaut, James M., Kirkman, Marion S., O’Kelly Phillips, Erin, Pinner, Kisha L., Porter, Beverly D., Roach, Paris J., Rowland, Nancy D., Wheeler, Madelyn L., Ratner, Robert E., Aroda, Vanita, Magee, Michelle, Youssef, Gretchen, Shapiro, Sue, Andon, Natalie, Bavido-Arrage, Catherine, Boggs, Geraldine, Bronsord, Marjorie, Brown, Ernestine, Love Burkott, Holly, Cheatham, Wayman W., Cola, Susan, Evans, Cindy, Gibbs, Peggy, Kellum, Tracy, Leon, Lilia, Lagarda, Milvia, Levatan, Claresa, Lindsay, Milajurine, Nair, Asha K., Park, Jean, Passaro, Maureen, Silverman, Angela, Uwaifo, Gabriel, Wells-Thayer, Debra, Wiggins, Renee, Saad, Mohammed F., Watson, Karol, Budget, Maria, Jinagouda, Sujata, Botrous, Medhat, Sosa, Anthony, Tadros, Sameh, Akbar, Khan, Conzues, Claudia, Magpuri, Perpetua, Ngo, Kathy, Rassam, Amer, Waters, Debra, Xapthalamous, Kathy, Santiago, Julio V., Brown, Angela L., Santiago, Ana, Das, Samia, Khare-Ranade, Prajakta, Stich, Tamara, Fisher, Edwin, Hurt, Emma, Jones, Jackie, Jones, Tracy, Kerr, Michelle, McCowan, Sherri, Ryder, Lucy, Wernimont, Cormarie, Saudek, Christopher D., Hill Golden, Sherita, Bradley, Vanessa, Sullivan, Emily, Whittington, Tracy, Abbas, Caroline, Allen, Adrienne, Brancati, Frederick L., Cappelli, Sharon, Clark, Jeanne M., Charleston, Jeanne B., Freel, Janice, Horak, Katherine, Greene, Alicia, Jiggetts, Dawn, Johnson, Delois, Joseph, Hope, Kalyani, Rita, Loman, Kimberly, Mathioudakis, Nestoras, Maruthur, Nisa, Mosley, Henry, Reusing, John, Rubin, Richard R., Samuels, Alafia, Shields, Thomas, Stephens, Shawne, Stewart, Kerry J., Thomas, LeeLana, Utsey, Evonne, Williamson, Paula, Schade, David S., Adams, Karwyn S., Johannes, Carolyn, Hemphill, Claire, Hyde, Penny, Canady, Janene L., Atler, Leslie F., Boyle, Patrick J., Burge, Mark R., Chai, Lisa, Colleran, Kathleen, Fondino, Ateka, Gonzales, Ysela, Hernandez-McGinnis, Doris A., Katz, Patricia, King, Carolyn, Middendorf, Julia, Rubinchik, Sofya, Senter, Willette, Shamoon, Harry, Crandall, Jill, Brown, Janet O., Trandafirescu, Gilda, Powell, Danielle, Adorno, Elsie, Cox, Liane, Duffy, Helena, Engel, Samuel, Friedler, Allison, Goldstein, Angela, Howardentury, Crystal J., Lukin, Jennifer, Kloiber, Stacey, Longchamp, Nadege, Martinez, Helen, Pompi, Dorothy, Scheindlin, Jonathan, Tomuta, Norica, Violino, Elissa, Walker, Elizabeth A., Wylie-Rosett, Judith, Zimmerman, Elise, Zonszein, Joel, Wing, Rena R., Orchard, Trevor, Venditti, Elizabeth, Koenning, Gaye, Kramer, M. Kaye, Smith, Marie, Jeffries, Susan, Weinzierl, Valarie, Barr, Susan, Benchoff, Catherine, Boraz, Miriam, Clifford, Lisa, Culyba, Rebecca, Frazier, Marlene, Gilligan, Ryan, Guimond, Stephanie, Harrier, Susan, Harris, Louann, Kriska, Andrea, Manjoo, Qurashia, Mullen, Monica, Noel, Alicia, Otto, Amy, Pettigrew, Jessica, Rockette-Wagner, Bonny, Rubinstein, Debra, Semler, Linda, Smith, Cheryl F., Williams, Katherine V., Wilson, Tara, Arakaki, Richard F., Mau, Marjorie K., Latimer, Renee W., Isonaga, Mae K., Baker-Ladao, Narleen K., Bow, Ralph, Bermudez, Nina E., Dias, Lorna, Inouye, Jillian, Melish, John S., Mikami, Kathy, Mohideen, Pharis, Odom, Sharon K., Perry, Raynette U., Yamamoto, Robin E., Hanson, Robert L., Shah, Vallabh, Hoskin, Mary A., Percy, Carol A., Cooeyate, Norman, Natewa, Camille, Dodge, Charlotte, Enote, Alvera, Anderson, Harelda, Acton, Kelly J., Andre, Vickie L., Barber, Rosalyn, Begay, Shandiin, Bennett, Peter H., Benson, Mary Beth, Bird, Evelyn C., Broussard, Brenda A., Bucca, Brian C., Chavez, Marcella, Cook, Sherron, Curtis, Jeff, Dacawyma, Tara, Doughty, Matthew S., Duncan, Roberta, Edgerton, Cyndy, Ghahate, Jacqueline M., Glass, Justin, Glass, Martia, Gohdes, Dorothy, Grant, Wendy, Horse, Ellie, Ingraham, Louise E., Jackson, Merry, Jay, Priscilla, Kaskalla, Roylen S., Kavena, Karen, Kessler, David, Kobus, Kathleen M., Krakoff, Jonathan, Kurland, Jason, Manus, Catherine, McCabe, Cherie, Michaels, Sara, Morgan, Tina, Nashboo, Yolanda, Nelson, Julie A., Poirier, Steven, Polczynski, Evette, Piromalli, Christopher, Reidy, Mike, Roumain, Jeanine, Rowse, Debra, Roy, Robert J., Sangster, Sandra, Sewenemewa, Janet, Smart, Miranda, Spencer, Chelsea, Tonemah, Darryl, Williams, Rachel, Wilson, Charlton, Yazzie, Michelle, Bain, Raymond, Fowler, Sarah, Larsen, Michael D., Jablonski, Kathleen, Temprosa, Marinella, Brenneman, Tina, Edelstein, Sharon L., Abebe, Solome, Bamdad, Julie, Barkalow, Melanie, Bethepu, Joel, Bezabeh, Tsedenia, Bowers, Anna, Butler, Nicole, Callaghan, Jackie, Carter, Caitlin E., Christophi, Costas, Dwyer, Gregory M., Foulkes, Mary, Gao, Yuping, Gooding, Robert, Gottlieb, Adrienne, Grimes, Kristina L., Grover-Fairchild, Nisha, Haffner, Lori, Hoffman, Heather, Jones, Steve, Jones, Tara L., Katz, Richard, Kolinjivadi, Preethy, Lachin, John M., Ma, Yong, Mucik, Pamela, Orlosky, Robert, Reamer, Susan, Rochon, James, Sapozhnikova, Alla, Sherif, Hanna, Stimpson, Charlotte, Hogan Tjaden, Ashley, Walker-Murray, Fredricka, Venditti, Elizabeth M., Kriska, Andrea M., Weinzierl, Valerie, Marcovina, Santica, Aldrich, F. Alan, Harting, Jessica, Albers, John, Strylewicz, Greg, Killeen, Anthony, Gabrielson, Deanna, Eastman, R., Fradkin, Judith, Garfield, Sanford, Lee, Christine, Gregg, Edward, Zhang, Ping, O’Leary, Dan, Evans, Gregory, Budoff, Matthew, Dailing, Chris, Stamm, Elizabeth, Schwartz, Ann, Navy, Caroline, Palermo, Lisa, Rautaharju, Pentti, Prineas, Ronald J., Soliman, Elsayed Z., Alexander, Teresa, Campbell, Charles, Hall, Sharon, Li, Yabing, Mills, Margaret, Pemberton, Nancy, Rautaharju, Farida, Zhang, Zhuming, Hu, Julie, Hensley, Susan, Keasler, Lisa, Taylor, Tonya, Danis, Ronald, Davis, Matthew, Hubbard, Larry, Endres, Ryan, Elsas, Deborah, Johnson, Samantha, Myers, Dawn, Barrett, Nancy, Baumhauer, Heather, Benz, Wendy, Cohn, Holly, Corkery, Ellie, Dohm, Kristi, Domalpally, Amitha, Gama, Vonnie, Goulding, Anne, Ewen, Andy, Hurtenbach, Cynthia, Lawrence, Daniel, McDaniel, Kyle, Pak, Jeong, Reimers, James, Shaw, Ruth, Swift, Maria, Vargo, Pamela, Watson, Sheila, Manly, Jennifer, Mayer-Davis, Elizabeth, Moran, Robert R., Ganiats, Ted, David, Kristin, Sarkin, Andrew J., Groessl, Erik, Katzir, Naomi, Chong, Helen, Herman, William H., Brändle, Michael, Brown, Morton B., Altshuler, David, Billings, Liana K., Chen, Ling, Harden, Maegan, Pollin, Toni I., Shuldiner, Alan R., Franks, Paul W., and Hivert, Marie-France

Subjects
Advanced and Specialized Nursing, Endocrinology, Diabetes and Metabolism, Internal Medicine, Pathophysiology/Complications
Abstract

OBJECTIVE To determine whether interventions that slow or prevent the development of type 2 diabetes in those at risk reduce the subsequent prevalence of diabetic retinopathy. RESEARCH DESIGN AND METHODS The Diabetes Prevention Program (DPP) randomized subjects at risk for developing type 2 diabetes because of overweight/obesity and dysglycemia to metformin (MET), intensive lifestyle intervention (ILS), or placebo (PLB) to assess the prevention of diabetes. During the DPP and DPP Outcome Study (DPPOS), we performed fundus photography over time on study participants, regardless of their diabetes status. Fundus photographs were graded using the Early Treatment Diabetic Retinopathy Study grading system, with diabetic retinopathy defined as typical lesions of diabetic retinopathy (microaneurysms, exudates, or hemorrhage, or worse) in either eye. RESULTS Despite reduced progression to diabetes in the ILS and MET groups compared with PLB, there was no difference in the prevalence of diabetic retinopathy between treatment groups after 1, 5, 11, or 16 years of follow-up. No treatment group differences in retinopathy were found within prespecified subgroups (baseline age, sex, race/ethnicity, baseline BMI). In addition, there was no difference in the prevalence of diabetic retinopathy between those exposed to metformin and those not exposed to metformin, regardless of treatment group assignment. CONCLUSIONS Interventions that delay or prevent the onset of type 2 diabetes in overweight/obese subjects with dysglycemia who are at risk for diabetes do not reduce the development of diabetic retinopathy for up to 20 years.

Published
2022

8. High Rates of Undiagnosed and Uncontrolled Hypertension Upon a Screening Campaign in Rural Rwanda: a Cross-sectional Study

Author

Ntaganda, Evariste, primary, Mugeni, Regine, additional, Harerimana, Emmanuel, additional, Ngoga, Gedeon, additional, Dusabeyezu, Symaque, additional, Uwinkindi, Francois, additional, Utumatwishima, Jean Nepo A., additional, Mutimura, Eugene, additional, Davila-Roman, Victor G., additional, Schechtman, Kenneth, additional, Nishimwe, Aurore, additional, Twizeyimana, Laurence, additional, Brown, Angela L., additional, Cade, Todd W., additional, Bushaku, Marcus, additional, Fuentes, Lisa De Las, additional, Reeds, Dominic, additional, and Twagirumukiza, Marc, additional

Published
2021
Full Text
View/download PDF

9. Exploring contextual factors influencing the implementation of evidence-based care for hypertension in Rwanda: a cross-sectional study using the COACH questionnaire

Author

Baumann, Ana A, primary, Hooley, Cole, additional, Goss, Charles W, additional, Mutabazi, Vincent, additional, Brown, Angela L, additional, Schechtman, Kenneth B, additional, Twagirumukiza, Marc, additional, de las Fuentes, Lisa, additional, Reeds, Dominic, additional, Williams, Makeda, additional, Mutimura, Eugene, additional, Bergström, Anna, additional, Nishimwe, Aurore, additional, Ingabire, Cecile, additional, and Davila-Roman, Victor G, additional

Published
2021
Full Text
View/download PDF

11. Exploring contextual factors influencing the implementation of evidence-based care for hypertension in Rwanda : a cross-sectional study using the COACH questionnaire

Author

Baumann, Ana A., Hooley, Cole, Goss, Charles W., Mutabazi, Vincent, Brown, Angela L., Schechtman, Kenneth B., Twagirumukiza, Marc, de las Fuentes, Lisa, Reeds, Dominic, Williams, Makeda, Mutimura, Eugene, Bergström, Anna, Nishimwe, Aurore, Ingabire, Cecile, Davila-Roman, Victor G., Baumann, Ana A., Hooley, Cole, Goss, Charles W., Mutabazi, Vincent, Brown, Angela L., Schechtman, Kenneth B., Twagirumukiza, Marc, de las Fuentes, Lisa, Reeds, Dominic, Williams, Makeda, Mutimura, Eugene, Bergström, Anna, Nishimwe, Aurore, Ingabire, Cecile, and Davila-Roman, Victor G.

Abstract

Importance Hypertension is the largest contributor to the Global Burden of Disease. In Rwanda, as in most low-income and middle-income countries, an increasing prevalence of hypertension and its associated morbidity and mortality is causing major healthcare and economic impact. Understanding healthcare systems context in hypertension care is necessary. Objective To study the hypertension healthcare context as perceived by healthcare providers using the Context Assessment for Community Health (COACH) tool. Design A cross-sectional cohort responded to the COACH questionnaire and a survey about hypertension training. Setting Three tertiary care hospitals in Rwanda. Participants Healthcare professionals (n=223). Primary outcome(s) and measure(s) The COACH tool consists of 49 items with eight subscales: resources, community engagement, commitment to work, informal payment, leadership, work culture, monitoring services for action (5-point Likert Scale) and sources of knowledge (on a 0-1 scale). Four questions surveyed training on hypertension. Results Responders (n=223, 75% women; 56% aged 20-35 years) included nurses (n=142, 64%, midwives (n=42, 19%), primary care physicians (n=28, 13%) and physician specialists (n=11, 5%)). The subscales commitment to work, leadership, work culture and informal payment scored between 4.7 and 4.1 and the community engagement, monitoring services for action and organizational resources scored between 3.1 and 3.5. Sources of knowledge had a mean score of 0.6 +/- 0.3. While 73% reported having attended a didactic hypertension seminar in the past year, only 28% had received long-term training and 51% had <3-year experience working with hypertension care delivery. The majority (99%) indicated a need for additional training in hypertension care. Conclusions There is a need for increased and continuous training in Rwanda. Healthcare responders stated a commitment to work and reported supportive leadership, while acknowledging limited resourc

Published
2021
Full Text
View/download PDF

17. Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation

Author

Baumann, Ana A., primary, Mutabazi, Vincent, additional, Brown, Angela L., additional, Hooley, Cole, additional, Reeds, Dominic, additional, Ingabire, Cecile, additional, Ndahindwa, Vedaste, additional, Nishimwe, Aurore, additional, Cade, W. Todd, additional, De las Fuentes, Lisa, additional, Proctor, Enola K., additional, Karengera, Stephen, additional, Schecthman, Kenneth B., additional, Goss, Charles W., additional, Yarasheski, Kevin, additional, Newsome, Brad, additional, Mutimura, Eugene, additional, and Davila-Roman, Victor G., additional

Published
2019
Full Text
View/download PDF

18. High screen failure rate in patients with resistant hypertension: Findings from SYMPLICITY HTN-3

Author

Waksman, Ron, primary, Bakris, George L., additional, Steinvil, Arie, additional, Garcia-Garcia, Hector, additional, Brown, Angela L., additional, DiFilippo, William, additional, Scott, Thomas, additional, Singh, Jasvindar, additional, DeBruin, Vanessa, additional, Jones, Denise, additional, Jolivette, Dan, additional, and Bhatt, Deepak L., additional

Published
2017
Full Text
View/download PDF

19. Prostate Cancer Isn't Colorblind

Author

Hall, Lannis, Bullock, Arnold D., Brown, Angela L., and Colditz, Graham

Subjects
Cancer screening -- Methods, Prostate cancer -- Risk factors -- Patient outcomes -- Diagnosis, General interest, News, opinion and commentary
Abstract

St. Louis -- In 1966, the Rev. Dr. Martin Luther King Jr. said, ''Of all the forms of inequality, injustice in health care is the most shocking and inhuman.'' While [...]

Published
2016

20. Hypertension in African Americans Aged 60 to 79 Years: Statement From the International Society of Hypertension in Blacks

Author

Egan, Brent M., primary, Bland, Veita J., additional, Brown, Angela L., additional, Ferdinand, Keith C., additional, Hernandez, German T., additional, Jamerson, Kenneth A., additional, Johnson, Wallace R., additional, Kountz, David S., additional, Li, Jiexiang, additional, Osei, Kwame, additional, Reed, James W., additional, and Saunders, Elijah, additional

Published
2015
Full Text
View/download PDF

21. LA gateway chapter builds strong foundation for success

Author

Brown, Angela L.

Subjects
United States. Department of Defense -- Conferences, meetings and seminars, Educational programs -- Service introduction, Company service introduction, Business, Business, general, National Contract Management Association -- Licensing, certification and accreditation, National Contract Management Association -- Service introduction
Published
2006

22. Management of High Blood Pressure in Blacks

Author

Flack, John M., primary, Sica, Domenic A., additional, Bakris, George, additional, Brown, Angela L., additional, Ferdinand, Keith C., additional, Grimm, Richard H., additional, Hall, W. Dallas, additional, Jones, Wendell E., additional, Kountz, David S., additional, Lea, Janice P., additional, Nasser, Samar, additional, Nesbitt, Shawna D., additional, Saunders, Elijah, additional, Scisney-Matlock, Margaret, additional, and Jamerson, Kenneth A., additional

Published
2010
Full Text
View/download PDF

23. Management of Hypertension in Patients With Ventricular Assist Devices: A Scientific Statement From the American Heart Association.

Author

Eisen, Howard J., Flack, John M., Atluri, Pavan, Bansal, Neha, Breathett, Khadijah, Brown, Angela L., Hankins, Shelley R., Khazanie, Prateeti, Masri, Carolina, Pirlamarla, Preethi, and Rowe, Theresa

Abstract

Mechanical circulatory support with durable continuous-flow ventricular assist devices has become an important therapeutic management strategy for patients with advanced heart failure. As more patients have received these devices and the duration of support per patient has increased, the postimplantation complications have become more apparent, and the need for approaches to manage these complications has become more compelling. Continuous-flow ventricular assist devices, including axial-flow and centrifugal-flow pumps, are the most commonly used mechanical circulatory support devices. Continuous-flow ventricular assist devices and the native heart have a constant physiological interplay dependent on pump speed that affects pressure-flow relationships and patient hemodynamics. A major postimplantation complication is cerebrovascular vascular accidents. The causes of cerebrovascular vascular accidents in ventricular assist device recipients may be related to hypertension, thromboembolic events, bleeding from anticoagulation, or some combination of these. The most readily identifiable and preventable cause is hypertension. Hypertension management in these patients has been hampered by the fact that it is difficult to accurately measure blood pressure because these ventricular assist devices have continuous flow and are often not pulsatile. Mean arterial pressures have to be identified by Doppler or oscillometric cuff and treated. Although guidelines for hypertension management after ventricular assist device implantation are based largely on expert consensus and conventional wisdom, the mainstay of treatment for hypertension includes guideline-directed medical therapy for heart failure with reduced ejection fraction because this may reduce adverse effects associated with hypertension and increase the likelihood of favorable ventricular remodeling. The use of systemic anticoagulation in ventricular assist device recipients may at a given blood pressure increase the risk of stroke. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

24. 979-P: The Relationship between Physical Activity (PA) and Coronary Artery Calcification (CAC) by Sex in Adults with Impaired Glucose Tolerance (IGT) or Diabetes.

Author

ROCKETTE-WAGNER, BONNY, KRISKA, ANDREA, YOUNES, NAJI, EDELSTEIN, SHARON, ORCHARD, TREVOR J., ARMSTRONG, MARNI, BROWN, ANGELA L., DABELEA, DANA, GADDE, KISHORE M., HORTON, EDWARD, HOSKIN, MARY A., IBEBUOGU, UZOMA N., SCHLÖGL, MATHIAS, and GOLDBERG, RONALD B.

Abstract

Subclinical markers of atherosclerosis, including CAC, are less favorable in adults with IGT. In previous adult studies, higher PA has been associated with lower CAC with findings varying by age and sex. PA and CAC were examined by age and sex in the diverse Diabetes Prevention Program Outcomes Study (DPPOS) cohort with IGT who were randomized at baseline to lifestyle intervention, metformin, or placebo groups for a mean of 3.2 years, and subsequently observed in DPPOS for follow-up. PA was measured via questionnaire (annually); accelerometry once at 11-13yrs and CAC Agatston score (AS) using chest computed tomography at 13-15 yrs from randomization. The relationship between PA and CAC was examined using Tobit regression models in 1434 participants with valid PA and CAC data (mean age 63±9.5 yrs; 70% female; 54% with diabetes) adjusted for treatment group, age, sex, race/ethnicity, lipid medication use, diabetes status, and cumulative metformin exposure; pairwise and three-way interactions were examined. Accelerometry-assessed median (IQR) daily step counts and moderate+ PA (MVPA) minutes were 5302 (3576, 7104) and 21 (9, 41), respectively. Median (IQR) AS was 9 (0, 151). In fully adjusted models, each 1000 steps /day was associated with lower CAC (p=0.024). Results were examined by sex and age subgroups (<65 and ≥65 yrs) with significant inverse associations found in women (<65 and ≥65 yrs; both p<0.001) but not in men (<65 and ≥65 yrs; both p>0.05). Similarly, significant inverse associations between MVPA minutes and CAC AS were found in women (<65 yrs p=0.003; ≥65 yrs p=0.012) but not in men (<65 yrs p=0.91 and ≥65 yrs p=0.056). Questionnaire-measured PA and CAC associations showed similar trends. In contrast, minutes of sedentary and light PA were not significantly associated with CAC. Suggested sex differences in the PA-CAC association in adults with initial glucose intolerance was found and should be investigated in other studies. Disclosure: B. Rockette-wagner: None. E. Horton: None. M. A. Hoskin: None. U. N. Ibebuogu: None. M. Schlögl: None. R. B. Goldberg: None. D. Research group: None. A. Kriska: None. N. Younes: None. S. Edelstein: None. T. J. Orchard: None. M. Armstrong: None. A. L. Brown: Research Support; Self; Medtronic, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases. D. Dabelea: None. K. M. Gadde: Other Relationship; Self; AstraZeneca, Research Support; Self; BioKier, National Institute of Diabetes and Digestive and Kidney Diseases. Funding: National Institute of Diabetes and Digestive and Kidney Diseases (U01DK048489) [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

26. Pre-Endoscopic Rockall and Blatchford Scores to Identify Which Emergency Department Patients with Suspected Gastrointestinal Bleed Do Not Need Endoscopic Hemostasis.

Author

Meltzer, Andrew C., Burnett, Sarah, Pinchbeck, Carrie, Brown, Angela L., Choudhri, Tina, Yadav, Kabir, Fleischer, David E., and Pines, Jesse M.

Subjects
*GASTROINTESTINAL hemorrhage, *ENDOSCOPIC hemostasis, *EMERGENCY medical services, *ELECTRONIC health records, *HOSPITAL admission & discharge, *EMERGENCY medicine, *PATIENTS
Abstract

Abstract: Background: The pre-endoscopic Rockall Score (RS) and the Glasgow-Blatchford Scores (GBS) can help risk stratify patients with upper gastrointestinal bleed who are seen in the Emergency Department (ED). The RS and GBS have yet to be validated in a United States patient population for their ability to discriminate which ED patients with upper gastrointestinal bleed do not need endoscopic hemostasis. Objective: We sought to determine whether patients who received a score of zero on either score (the lowest risk) in the ED still required upper endoscopic hemostasis during hospitalization. Methods: Retrospective electronic medical record chart review was performed during a 3-year period (2007–2009) to identify patients with suspected upper gastrointestinal bleed by ED final diagnosis of gastrointestinal hemorrhage and related terms at a single urban academic ED. The RS and GBS were calculated from ED chart abstraction and the hospital records of admitted patients were queried for subsequent endoscopic hemostasis. Results: Six hundred and ninety patients with gastrointestinal bleed were identified and 86% were admitted to the hospital. One hundred and twenty-two patients had an RS equal to zero; 67 (55%; 95% confidence interval [CI] 46–63%) of these patients were admitted to the hospital and 11 (16%; 95% CI 9–27%) received endoscopic hemostasis. Sixty-three patients had a GBS equal to zero; 15 (24%; 95% CI 15–36%) were admitted to the hospital and 2 (13%; 95% CI 4–38%) received endoscopic hemostasis. Conclusions: Some patients who were identified as lowest risk by the GBS or RS still received endoscopic hemostasis during hospital admission. These clinical decision rules may be insufficiently sensitive to predict which patients do not require endoscopic hemostasis. [Copyright &y& Elsevier]

Published
2013
Full Text
View/download PDF

27. Metabolic syndrome is associated with abnormal left ventricular diastolic function independent of left ventricular mass.

Author

de las Fuentes L, Brown AL, Mathews SJ, Waggoner AD, Soto PF, Gropler RJ, and Dávila-Román VG

Subjects
Adult, Aged, Cross-Sectional Studies, Diastole, Female, Heart Ventricles pathology, Humans, Male, Metabolic Syndrome pathology, Middle Aged, Ultrasonography, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left pathology, Waist-Hip Ratio, Metabolic Syndrome complications, Ventricular Dysfunction, Left etiology
Abstract

Aim: To characterize the extent to which metabolic syndrome criteria predict left ventricular (LV) structure and function., Methods and Results: Metabolic syndrome criteria were assessed in 607 adults with normal LV function. The cohort was grouped according to the number of criteria satisfied: (1) Absent (0 criteria, n = 110); (2) Pre-Metabolic Syndrome (1-2 criteria, n = 311); and (3) Metabolic Syndrome (>or=3 criteria, n = 186). Echocardiography was used to assess LV structure (LV mass) and systolic (LVEF, Vs) and diastolic function, by pulse-wave Doppler (E/A ratio) and tissue Doppler imaging (Ve). LV volumes and LVEF were similar between groups. However, LV mass increased significantly and progressively (LVM/Ht(2.7), in g/m(2.7): 34.9 +/- 6.7, 41.0 +/- 9.5, 46.3 +/- 11.0, P < 0.001); LV relaxation decreased progressively (Ve(global'), in cm/s: 13.5 +/- 2.8, 12.1 +/- 3.0, 10.5 +/- 2.2, P < 0.001) from Absent to Pre-Metabolic Syndrome to Metabolic Syndrome groups, respectively. Multiple variable analyses showed that diastolic blood pressure, waist circumference, and triglyceride levels were independent predictors of Ve after adjustment for LV mass., Conclusion: Patients with metabolic syndrome have LV diastolic dysfunction independent of LV mass. These functional abnormalities may partially explain the increased cardiovascular morbidity and mortality associated with metabolic syndrome.

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results