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The article discusses the life and works of American artist Alexis Brown. Topics include her family background, her interests in theater and visual arts which persuaded her to take up art classes in different universities, the composition of her first operetta "Focacciatown" in 2015 and her first solo show in 2017.

The article discusses the ethical issues brought on by advances in human performance enhancement (HPE), focusing mainly on biotechnology. Ethical dilemmas likely will exist across the HPE spectrum like ethical implications in conducting psychological screening and training in Airmen. The article urged not to view HPE to be inherently unethical as it may be ethical in terms of beneficience. Recommendations are then presented on new science and technology advances with potential HPE applications.

Editorial. Talks about environmental planning and management in the Asia-Pacific region. Role of planners and planning in implementing sustainability; How to achieve sustainability.

Background: There is increasing evidence that a complex interplay of factors within environments in which children grows up, contributes to children's suboptimal mental health and cognitive development. The concept of the life-course exposome helps to study the impact of the physical and social environment, including social inequities, on cognitive development and mental health over time., Methods: Equal-Life develops and tests combined exposures and their effects on children's mental health and cognitive development. Data from eight birth-cohorts and three school studies (N = 240.000) linked to exposure data, will provide insights and policy guidance into aspects of physical and social exposures hitherto untapped, at different scale levels and timeframes, while accounting for social inequities. Reasoning from the outcome point of view, relevant stakeholders participate in the formulation and validation of research questions, and in the formulation of environmental hazards. Exposure assessment combines GIS-based environmental indicators with omics approaches and new data sources, forming the early-life exposome. Statistical tools integrate data at different spatial and temporal granularity and combine exploratory machine learning models with hypothesis-driven causal modeling., Conclusions: Equal-Life contributes to the development and utilization of the exposome concept by (1) integrating the internal, physical and social exposomes, (2) studying a distinct set of life-course effects on a child's development and mental health (3) characterizing the child's environment at different developmental stages and in different activity spaces, (4) looking at supportive environments for child development, rather than merely pollutants, and (5) combining physical, social indicators with novel effect markers and using new data sources describing child activity patterns and environments., Competing Interests: The authors declare that they have no conflicts of interest with regard to the content of this report., (Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The Environmental Epidemiology. All rights reserved.)

Introduction: Specific mechanisms leading to acute neck injury in flight as a result of +Gz exposure remain unclear. In this study, head positions adopted by aircrew in air combat have been quantified, and the associated levels of cervical muscle activation have been determined., Method: Six fast jet aircrew subjects were instrumented with surface electromyography (EMG) electrodes, and activation potentials from neck erector spinae (ES) and sternocleidomastoid (SC) muscles were logged on a data recorder. EMG signal was normalized to preflight maximum voluntary contraction (MVC). All subjects flew a one-on-one air combat sortie in a Hawk T1 aircraft comprising at least four air combat engagements. In-cockpit video and +Gz acceleration were recorded. Time-synchronized analysis of video, EMG, and acceleration were conducted for head position and normalized muscle activation (%MVC)., Results: During air combat, the head was away from neutral for 68% of the time, predominantly in extension, or rotation plus extension. During neck extension under G, 40-80% MVC occurred in the ES: this was reduced by half when the canopy was used as a support. Similar activation occurred in the SC in neck extension plus rotation. The ES was activated at over 40% MVC for 25% of the engagement duration. Postsortie, 35% reduction in neck muscle strength occurred., Conclusions: Extreme neck extension +/- rotation is very common in air combat and is associated with high levels of muscle activation and fatigue. This information can be used to help devise targeted neck conditioning and positioning strategies in order to reduce injury risk.