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312 results on '"Brueckner, R."'

25. Earlier identification of children with autism spectrum disorder: An automatic vocalisation-based approach

Author

Pokorny, F., Schuller, B., Marschik, P., Brueckner, R., Nyström, P., Cummins, N., Bolte, Sven, Einspieler, C., Falck-Ytter, T., Pokorny, F., Schuller, B., Marschik, P., Brueckner, R., Nyström, P., Cummins, N., Bolte, Sven, Einspieler, C., and Falck-Ytter, T.

Abstract

Copyright © 2017 ISCA. Autism spectrum disorder (ASD) is a neurodevelopmental disorder usually diagnosed in or beyond toddlerhood. ASD is defined by repetitive and restricted behaviours, and deficits in social communication. The early speech-language development of individuals with ASD has been characterised as delayed. However, little is known about ASD-related characteristics of pre-linguistic vocalisations at the feature level. In this study, we examined pre-linguistic vocalisations of 10-month-old individuals later diagnosed with ASD and a matched control group of typically developing individuals (N = 20). We segmented 684 vocalisations from parent-child interaction recordings. All vocalisations were annotated and signal-analytically decomposed. We analysed ASD-related vocalisation specificities on the basis of a standardised set (eGeMAPS) of 88 acoustic features selected for clinical speech analysis applications. 54 features showed evidence for a differentiation between vocalisations of individuals later diagnosed with ASD and controls. In addition, we evaluated the feasibility of automated, vocalisation-based identification of individuals later diagnosed with ASD.We compared linear kernel support vector machines and a 1-layer bidirectional long short-term memory neural network. Both classification approaches achieved an accuracy of 75% for subject-wise identification in a subject-independent 3-fold cross-validation scheme. Our promising results may be an important contribution en-route to facilitate earlier identification of ASD.

Published
2017

26. Hämatologie/Onkologie

Author

Bodemann, H. H., Rieger, A., Schröter-Urban, H., Volk, B. A., Bross, K., Gerok, W., Löhr, G. W., Heilmann, E., Ridderskamp, P., Baumgart, P., Winkelmann, M., Schmitz, G., Aul, C., Scharf, R. E., Pfitzer, P., Schneider, W., Heisig, S., Hinterberger, W., Gadner, H., Höcker, P., Neumann, E., Schmidmeier, W., Bettelheim, P., Lechner, K., Deutsch, E., Arnold, R., Carbonell, F., Fliedner, T. M., Friedrich, W., Goldmann, S. F., Heimpel, H., Heit, W., Kleihauer, E., Kohne, E., Kubanek, B., Kurrle, E., Lohrmann, H. P., Pflieger, H., Schmeiser, T., Fritz, E., Radaszkiewicz, T., Dorda, W., Ludwig, H., Weh, H. J., Kuse, R., Hausmann, K., Hossfeld, D. K., Gerecke, D., Kreß, M., Gross, R., Heinz, R., Aiginger, P., Pont, J., Schüller, J., Walcher, G., Hanak, H., Sinn, E., Wirth, M., Dittrich, Ch., Schwarzmeier, J., Kühböck, J., Honetz, N., Alth, G., Stacher, A., Bartels, H., Lennert, K., Köttgen, E., Schölmerich, J., Rühle, K. H., Heim, M. E., Bojar, H., Saeger, H., Queißer, W., Schick, E., Frey, H. O., Holm, E., Luster, W., Gropp, C., Havemann, K., Hehlmann, R., Schreiber, A. M., Kreeb, G., Luz, A., Mesa-Tejada, R., Lohe, J. K., Prechtel, K., Schalhorn, A., Sauer, H., Wilmanns, W., Stupp-Poutot, G., Schuchhardt, C., Fiebig, H. H., Henß, H., Koch, H., Heinrich, E., Labedzki, L., Hartlapp, H. J., WeiBbach, L., von Heyden, H. W., Hansen, D., Nagel, G. A., Hoffmann, H., Schneider, B., Hinterberger, R., Fischer, J., Preiß, J., Weigand, H., Brückner, R., Schreml, W., Hügl, W., Koßmann, B., Manegold, C., Abel, U., Fritze, D., Herrmann, R., Niederle, N., Kurschel, E., Schmidt, C. G., Schnitzler, G., König, H. J., Katz, R., Trux, F. A., Bloch, R., Keymling, M., Wolkewitz, K. D., Fritsch, H., Hanisch, I., Brumen, L., Edler, L., Hartlapp, J. H., Schmidt, R. E., Illiger, J. H., Krieger, D., Hoelzer, D., and Schlegel, Bernhard, editor

Published
1983
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29. CLINICAL HETEROGENEITY AND ITS POTENTIAL THERAPEUTIC IMPLICATIONS IN CHILDREN WITH SCN2A-RELATED DISORDERS

Author

Ceulemans, B., Lederer, D., Dorn, T., Helbig, K. L., Hardies, K., Stamberger, H., de Jonghe, P., Weckhuysen, S., Lemke, J. R., Helbig, I, Kluger, G., Moller, R. S., Johannesen, K. M., Wolf, M., Masnada, S., Rubboli, G., Gardella, E., Milh, M., Villard, L., Mignot, C., Lardennois, C., Bourel-Ponchel, Emilie, Nava, C., Lesca, G., Gerard, M., Perrin, L., Doummar, D., Auvin, S., Miranda, M. J., Brilstra, E., Knoers, N., Doecker, M., Bast, T., Loddenkemper, T., Wong-Kisiel, L., Baumeister, F. M., Fazeli, W., Striano, P., Kurlemann, G., Klepper, J., Thoene, J. G., Arndt, D. H., Schmitt-Mechelke, T., Maier, O., Muhle, H., Wical, B., Finetti, C., Brueckner, R., Pietz, J., Golla, G., Jillella, D., Afenjar, A., Linnet, K. M., Charles, P., Oiglane-Slik, E., Mantovani, J. F., Deprez, M., Scalais, E., Lagae, L., Nikanorova, M., Hjalgrim, H., Depienne, C., Scheidecker, S., Kremer, V, Doray, B., Alembik, y., University of British Columbia (UBC), Pédiatrie spécialisée et médecine infantile (neurologie, pneumologie, maladies héréditaires du métabolisme) - Hôpital de la Timone, Ecole Polytechnique Fédérale de Lausanne (EPFL), Université de Strasbourg (UNISTRA), Centre National de la Recherche Scientifique (CNRS), Groupe de Recherche sur l'Analyse Multimodale de la Fonction Cérébrale - UMR INSERM_S 1105 (GRAMFC), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Insulaire du Vivant et de l'Environnement (LIVE), Université de la Nouvelle-Calédonie (UNC), Service de neuropédiatrie et maladies métaboliques [CHU Robert-Debré], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Robert Debré, Department of Child Neurology, Development and Rehabilitation [Hospital of Eastern Switzerland], Children's Hospital of Eastern Switzerland St.Gallen, Service de génétique et embryologie médicales [CHU Trousseau], CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de médecine interne et centre de référence des maladies rares [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], IMEC (IMEC), Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Statens seruminstitut, and Les Hôpitaux Universitaires de Strasbourg (HUS)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2016

36. Overview of ASDEX Upgrade Results

Author

Gruber, O., Bosch, H., Guenter, S., Herrmann, A., Kallenbach, A., Kaufmann, M., Krieger, K., Lackner, K., Mertens, V., Neu, R., Ryter, F., Schweinzer, J., Staebler, A., Suttrop, W., Wolf, R., Asmussen, K., Bard, A., Becker, G., Behler, K., Behringer, K., Bergmann, A., Bessenrodt-Weberpals, M., Borrass, K., Braams, B., Brambilla, M., Brandenburg, R., Braun, F., Brinkschulte, H., Brueckner, R., Bruesehaber, B., Buechl, K., Buhler, A., Callaghan, H., Carlson, A., Coster, D., Pena Hempel, S., Dorn, C., Drube, R., Dux, R., Egorov, S., Engelhardt, W., Fahrbach, H., Fantz, U., Feist, H., Franzen, P., Fuchs, J., Fussmann, G., Gafert, J., Gantenbein, G., Gehre, O., Geier, A., Gernhardt, J., Gubanka, E., Gude, A., Haas, G., Hallatschek, K., Hartmann, D., Heinemann, B., Herppich, G., Herrmann, W., Hofmeister, F., Holzhauer, E., Jacobi, D., Kakoulidis, M., Karakatsanis, N., Kardaun, O., Khutoretski, A., Kollotzek, H., Koetterl, S., Kraus, W., Kurzan, B., Kyriakakis, G., Lang, P., Lang, R., Laux, M., Lengyel, L., Leuterer, F., Lorenz, A., Maier, H., Manso, M., Maraschek, M., Markoulaki, M., Mast, K., McCarthy, P., Meisel, D., Meister, H., Merkel, R., Meskat, J., Mueller, H., Muenich, M., Murmann, H., Napiontek, B., Neu, G., Neuhauser, J., Niethammer, M., Noterdaeme, J., Pautasso, G., Peeters, A., Pereverzew, G., Pinches, S., Raupp, G., Reinmüller, K., Riedl, R., Rohde, V., Roehr, H., Roth, J., Salzmann, H., Sandmann, W., Schilling, H., Schloegl, D., Schmidtmann, K., Schneider, H., Schneider, R., Schneider, W., Schramm, G., Schweizer, S., Schwoerer, R., Scott, B., Seidel, U., Serra, F., Sesnic, S., Sihler, C., Silva, A., Speth, E., Steuer, K., Stober, J., Streibl, B., Thoma, A., Treutterer, W., Troppmann, M., Tsois, N., Ullrich, W., Ulrich, M., Varela, P., Verbeek, H., Vollmer, O., Wedler, H., Weinlich, M., Wenzel, U., Wesner, F., Wunderlich, R., Xantopoulosa, N., Yu, Q., and Zasche, D.

Published
1999

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