18 results on '"Bruno Mipinda"'
Search Results
2. Blood pressure-lowering medicines implemented in 12 African countries: the cross-sectional multination EIGHT study
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Xavier Jouven, Bamba Gaye, Marie Antignac, Ibrahima Bara Diop, Marie Cécile Perier, Jean Laurent Takombe, Dadhi Balde, Roland N'Guetta, Anastase Dzudie, Liliane Mfeukeu Kuate, Charles Kouam Kouam, Samuel Kingue, Adama Kane, Pauline Cavagna, Jean Marie Damorou, Stephane Méo Ikama, Kouadio Euloge Kramoh, Ibrahim Ali Toure, Beatriz Ferreira, Martin Houenassi, Suzy Gisele Kimbally-kaki, Emmanuel Limbole, Jean Bruno Mipinda, Carol Nhavoto, Abdallahi Sidy Ali, Gabriel S Tajeu, Diane Macquart De Terline, and Michel Azizi
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Medicine - Published
- 2021
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3. Factors associated with poor adherence to medication among hypertensive patients in twelve low and middle income Sub-Saharan countries.
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Diane Macquart de Terline, Adama Kane, Kouadio Euloge Kramoh, Ibrahim Ali Toure, Jean Bruno Mipinda, Ibrahima Bara Diop, Carol Nhavoto, Dadhi M Balde, Beatriz Ferreira, Martin Dèdonougbo Houenassi, Méo Stéphane Ikama, Samuel Kingue, Charles Kouam Kouam, Jean Laurent Takombe, Emmanuel Limbole, Liliane Mfeukeu Kuate, Roland N'guetta, Jean Marc Damorou, Zouwera Sesso, Abdallahi Sidy Ali, Marie-Cécile Perier, Michel Azizi, Jean Philippe Empana, Xavier Jouven, and Marie Antignac
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Medicine ,Science - Abstract
IntroductionOver the past few decades, the prevalence of hypertension has dramatically increased in Sub-Saharan Africa. Poor adherence has been identified as a major cause of failure to control hypertension. Scarce data are available in Africa.AimsWe assessed adherence to medication and identified socioeconomics, clinical and treatment factors associated with low adherence among hypertensive patients in 12 sub-Saharan African countries.MethodWe conducted a cross-sectional survey in urban clinics of both low and middle income countries. Data were collected by physicians on demographics, treatment and clinical data among hypertensive patients attending the clinics. Adherence was assessed by questionnaires completed by the patients. Factors associated with low adherence were investigated using logistic regression with a random effect on countries.ResultsThere were 2198 individuals from 12 countries enrolled in the study. Overall, 678 (30.8%), 738 (33.6%), 782 (35.6%) participants had respectively low, medium and high adherence to antihypertensive medication. Multivariate analysis showed that the use of traditional medicine (OR: 2.28, 95%CI [1.79-2.90]) and individual wealth index (low vs. high wealth: OR: 1.86, 95%CI [1.35-2.56] and middle vs. high wealth: OR: 1.42, 95%CI [1.11-1.81]) were significantly and independently associated with poor adherence to medication. In stratified analysis, these differences in adherence to medication according to individual wealth index were observed in low-income countries (pConclusionThis study revealed the high frequency of poor adherence in African patients and the associated factors. These findings should be useful for tailoring future programs to tackle hypertension in low income countries that are better adapted to patients, with a potential associated enhancement of their effectiveness.
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- 2019
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4. Létalité de l'insuffisance cardiaque au Centre Hospitalier Universitaire de Libreville (CHUL) et facteurs associés
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Elsa Ayo Bivigou, Mahutondji Christian Allognon, Francis Ndoume, Jean Bruno Mipinda, and Emmanuel Ecke Nzengue
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insuffisance cardiaque ,létalité ,facteurs associés ,libreville ,Medicine - Abstract
INTRODUCTION: L'insuffisance cardiaque (IC) est une cause fréquente de décès en Afrique. La présente étude a pour but de déterminer le taux de létalité de l'IC et de rechercher les facteurs associés. METHODES: il s'agissait d'une étude rétrospective transversale réalisée dans le service de cardiologie du CHUL. Elle portait sur l'analyse de dossiers de patients hospitalisés pour IC gauche ou globale colligés de Janvier 2014 à Décembre 2016. RESULTATS: la létalité était de 10,3%. L'âge moyen des patients décédés (n=64) était de 57,4 ,17 ans. Le délai moyen de prise en charge était de 15,18 jours et la décompensation faisait suite à un écart de traitement chez 51,4% des patients décédés. L'association hypertension artérielle et diabète augmentait significativement le risque de décès (OR= 2,2 (1,2-6,6)). Les facteurs associés à la létalité étaient essentiellement: l'hypotension artérielle (OR=6,8(3,2-14,1)), l'insuffisance rénale sévère (OR=3,5(1,7-7,2)), un index cardio-thoracique supérieur à 0,7 (OR= 54,4 (15,3-193,1)), une altération sévère de la fraction d'éjection ventriculaire gauche (OR= 3,0(1,5-5,9)) et un taux élevé de NT-proBNP (OR=3,5(1,2-10,5)). La mortalité augmentait significativement avec le nombre de comorbidités. Les décès étaient dus dans 28,4% des cas à une complication extracardiaque. CONCLUSION: la létalité de l'IC est liée à la sévérité et à la précocité des lésions. Le retard de prise en charge et les comorbidités aggravent cette létalité. Le dépistage des facteurs de risque et l'éducation thérapeutique pourraient diminuer cette mortalité qui concerne des sujets relativement jeunes.
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- 2018
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5. Development of the certificate course in the management of hypertension in Africa (CCMH-Africa): proceedings of the first continental faculty meeting, Nairobi, Kenya, 25–26 February 2018
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Albertino Damasceno, Brian Rayner, Francesco P. Cappuccio, Abdoul Kane, Jean Baptiste Anzouan Kacou, Michael A. Weber, Dorairaj Prabhakaran, Bertrand Fikahem Ellenga Mbolla, BC Anisiuba, Hamadou Ba, Bongani M. Mayosi, Andre Pascal Kengne, Neil R Poulter, Christian Delles, George Nel, Arun Jose, Frederick Bukachi, Habib Gamra, Bhalla Sandeep, Bernard Gitura, Amha Weldehana, Mohamed Awad, Dike B. Ojji, Euloge Kramoh, Ana Olga Mocumbi, Elijah Ogola, Calypse Ngwasiri, Brice Kitio, Aletta E Shutte, Anastase Dzudie, Bruno Mipinda, Mahmoud U Sani, Samuel Kingue, Ali Ibrahim Toure, Harun Otieno, and Saad Subhani
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medicine.medical_specialty ,business.industry ,Public health ,General Medicine ,Monitoring and evaluation ,Certification ,030204 cardiovascular system & hematology ,Certificate ,language.human_language ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Irish ,Action plan ,General partnership ,medicine ,language ,030212 general & internal medicine ,Cardiology and Cardiovascular Medicine ,business ,Curriculum - Abstract
BACKGROUND In response to the call by the World Health Organisation to reduce premature deaths from non-communicable diseases by 25% by the year 2025 (25×25), the Pan-African Society of Cardiology (PASCAR), in partnership with several organisations, including the World Heart Federation, have developed an urgent 10-point action plan to improve detection, treatment and control of hypertension in Africa. Priority six of this action plan is to promote a task-shifting/task-sharing approach in the management of hypertension. AIM This capacity-building initiative aims to enhance the knowledge, skills and core competences of primary healthcare physicians in the management of hypertension and related complications. METHODS In a collaborative approach with the International Society of Hypertension, the British and Irish Hypertension Society, the Public Health Foundation of India and the Centre for Chronic Disease Control, the PASCAR hypertension taskforce held a continental faculty meeting in Kenya on 25 and 26 February 2018 to review and discuss a process of effective contextualisation and implementation of the Indian hypertension management course on the African continent. RESULTS A tailored African course in terms of evidence-based learning, up-to-date curriculum and on-the-job training was developed with a robust monitoring and evaluation strategy. The course will be offered on a modular basis with a judicious mix of case studies, group discussions and contact sessions, with great flexibility to accommodate participants' queries. CONCLUSIONS Hypertension affects millions of people in Africa and if left untreated is a major cause of heart disease, kidney disease and stroke. CCMH-Africa will train in the next 10 years, 25 000 certified general physicians and 50 000 nurses, capable of adequately managing uncomplicated hypertension, thereby freeing the few available specialists to focus on severe or complicated cases.
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- 2018
6. Poor adherence to medication and salt restriction as a barrier to reaching blood pressure control in patients with hypertension: Cross-sectional study from 12 sub-Saharan countries
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Marie Antignac, Marie Cécile Perier, Liliane Mfeukeu Kuate, Carol Nhavoto, Dadhi M. Balde, Martin Dèdonougbo Houenassi, Yves N’da Kouakou N’goran, Adama Kane, Charles Kouam Kouam, Abdallahi Sidi Aly, Dominique Hounsou, Beatriz dos Santos Ferreira, Xavier Jouven, Florent Koffi, Michel Azizi, Emmanuel Limbole, Méo Stéphane Ikama, Ibrahim Ali Toure, Suzy Gisèle Kimbally-Kaki, Diane Macquart de Terline, Zouwera Sesso, Jean Philippe Empana, Kouadio Euloge Kramoh, Pierre-François Plouin, Jean Bruno Mipinda, Ibrahima Bara Diop, Kumar Narayanan, Samuel Kingue, Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), and Université de Paris (UP)
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Male ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Cross-sectional study ,[SDV]Life Sciences [q-bio] ,Black People ,Blood Pressure ,030204 cardiovascular system & hematology ,Medication Adherence ,Poor adherence ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Epidemiology ,medicine ,Humans ,In patient ,030212 general & internal medicine ,Africa South of the Sahara ,Antihypertensive Agents ,Aged ,2. Zero hunger ,business.industry ,General Medicine ,Odds ratio ,Diet, Sodium-Restricted ,Middle Aged ,Confidence interval ,3. Good health ,Cross-Sectional Studies ,Treatment Outcome ,Blood pressure ,Health Care Surveys ,Hypertension ,Salt restriction ,Female ,Cardiology and Cardiovascular Medicine ,business ,Risk Reduction Behavior - Abstract
Summary Background Sub-Saharan Africa is experiencing a rising burden of hypertension. Antihypertensive medications and diet are the cornerstone of effective hypertension control. Aims To assess adherence to medication and salt restriction in 12 sub-Saharan countries, and to study the relationship between adherence and blood pressure control in patients with hypertension. Methods We conducted a cross-sectional survey in urban clinics in twelve sub-Saharan countries. Data were collected on demographics, treatment and adequacy of blood pressure control in patients with hypertension attending the clinics. Adherence was assessed by questionnaires completed by the patients. Hypertension grades were defined according to European Society of Cardiology guidelines. Association between adherence and blood pressure control was investigated using multilevel logistic regression analysis, adjusting for age, sex and country. Results Among the 2198 patients, 77.4% had uncontrolled blood pressure, 34.0% were poorly adherent to salt restriction, 64.4% were poorly adherent to medication and 24.6% were poorly adherent to both. Poor adherence to salt restriction (odds ratio [OR] 1.33, 95% confidence interval [CI] 1.03–1.72), medication (OR 1.56, 95% CI 1.25–1.93) or both (OR 1.91 1.39–2.66) was related to uncontrolled blood pressure. Moreover, poor adherence to both medication and salt restriction was related to a 1.52-fold (95% CI 1.04–2.22), 1.8-fold (95% CI 1.22–2.65) and 3.08-fold (95% CI 2.02–4.69) increased likelihood of hypertension grade 1, 2 and 3, respectively. Conclusions High levels of poor adherence to salt restriction and medication were noted in this urban sub-Saharan study; both were significantly associated with uncontrolled blood pressure, representing major opportunities for intervention to improve hypertension control in sub-Saharan Africa.
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- 2020
7. Antihypertensive strategies and hypertension control in Sub-Saharan Africa
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Abdallahi Sidy Ali, Méo Stéphane Ikama, Murielle Hounkponou, Anastase Dzudie, Gabriel S. Tajeu, Jean Marie F. Damorou, Jean Laurent Takombe, Emmanuel Limbole, Ibrahim Ali Toure, Suzy Gisèle Kimbally-Kaki, Adama Kane, Xavier Jouven, Michel Azizi, Carol Nhavoto, Liliane Mfeukeu Kuate, Kouadio Euloge Kramoh, Samuel Kingue, Dadhi M. Balde, Martin Dèdonougbo Houenassi, Charles Kouam Kouam, Marie Antignac, Jean Bruno Mipinda, Beatriz Ferreira, Roland N'Guetta, Bamba Gaye, Ibrahima Bara Diop, Marie Cécile Perier, Diane Macquart de Terline, Pauline Cavagna, Pôle de Pharmacie - Santé Publique - Information médicale [CHU Saint-Antoine], CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), University Marien Ngouabi of Brazzaville (umng), Institute of Cardiology of Abidjan [Abidjan, Côte d’Ivoire], Ngaliema Hospital [Kinshasa, Democratic Republic of the Congo], University Hospital of Fann [Dakar, Senegal], University Hospital of Lamorde [Niamey, Niger], Department of Cardiology [Conakry, Guinea], University Hospital of Conakry [Conakry, Guinea], Douala General Hospital, Internal Medicine Department, Douala, Cameroun, Instituto do Coração [Maputo, Mozambique] (ICOR), National University hospital of Hubert K. MAGA [Cotonou, Bénin] (CNHU-HKM), Hôpital Aristide-Le-Dantec, University of Yaoundé [Cameroun], Régional Hospital [Bafoussam, Cameroon], University of Kinshasa (UNIKIN), University hospital of Libreville [Libreville, Gabon], Université de Lomé [Togo], Faculté des Sciences et Techniques [Nouakchott, Mauritania], Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), HAL-SU, Gestionnaire, Pôle de Pharmacie - Santé Publique - Information médicale [Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), and Faculty of Medicine, University of Kinshasa
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Sub saharan ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,Hypertension control ,Epidemiology ,business.industry ,MEDLINE ,developing countries ,030204 cardiovascular system & hematology ,Article ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Environmental health ,cardiology ,Hypertension ,Humans ,Medicine ,030212 general & internal medicine ,Cardiology and Cardiovascular Medicine ,business ,Africa South of the Sahara ,Antihypertensive Agents ,ComputingMilieux_MISCELLANEOUS ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,antihypertensive medications - Abstract
International audience
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- 2020
8. Cardiac Pacing in Sub-Saharan Africa JACC International
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Xavier, Jouven, Bara I, Diop, Kumar, Narayanan, Anicet, Adoubi, Serigne Abdou, Ba, Dahdi, Balde, Jean-Marie, Damorou, Mamadou Bacary, Diarra, Anastase, Dzudie, Beatriz, Ferreira, Sedonougbo Martin, Houenassi, Meo-Stephane, Ikama, Abdoul, Kane, Adama, Kane, Samuel, Kingue, Jean-Bruno, Mipinda, Ana-Olga, Mocumbi, Ali, Niakara, Merimee, Ouankou, Abdallahi, Aly Sidi, Jean-Laurent, Takombe, Ibrahim Ali, Toure, Patrice, Zabsonré, David S, Celermajer, Antoine, Lafont, Bernard, Dodinot, Pascal, Sagnol, Eloi, Marijon, Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)
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Pacemaker, Artificial ,[SDV]Life Sciences [q-bio] ,Cardiac Pacing, Artificial ,Humans ,Medical Missions ,Africa South of the Sahara - Abstract
Many parts of the developing world, especially Sub-Saharan Africa, completely lack access to cardiac pacing. The authors initiated a multinational program to implement cardiac pacing in 14 countries in Sub-Saharan Africa (1996 to 2018), aiming to eventually build self-sustainable capacity in each country. This was based on an "on-site training" approach of performing procedures locally and educating local health care teams to work within resource-limited settings, with prospective evaluation of the program. In 64 missions, a total of 542 permanent pacemakers were implanted. In 11 of these countries, the first pacemaker implant in the country was through the mission. More than one-half of those initially listed as suitable died before the mission(s) arrived. The proportion of implantations that were completely handled by local teams increased from 3% in 1996 to 98% in 2018. These findings demonstrate the feasibility and effectiveness of a proctorship-based approach to the development of local cardiac pacing capabilities in Sub-Saharan African nations.
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- 2019
9. Antihypertensive strategies and hypertension control in Sub-Saharan Africa
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Cavagna, Pauline, primary, Stéphane Ikama, Méo, additional, Euloge Kramoh, Kouadio, additional, Laurent Takombe, Jean, additional, Bara Diop, Ibrahima, additional, Ali Toure, Ibrahim, additional, Balde, Dadhi M, additional, Dzudie, Anastase, additional, Ferreira, Beatriz, additional, Houenassi, Martin D, additional, Hounkponou, Murielle, additional, Kane, Adama, additional, Kimbally-Kaki, Suzy G, additional, Kingue, Samuel, additional, Kouam Kouam, Charles, additional, Limbole, Emmanuel, additional, Mfeukeu Kuate, Liliane, additional, Bruno Mipinda, Jean, additional, N’guetta, Roland, additional, Nhavoto, Carol, additional, Marie Damorou, Jean, additional, Sidy Ali, Abdallahi, additional, Gaye, Bamba, additional, Tajeu, Gabriel S, additional, Macquart de Terline, Diane, additional, Cécile Perier, Marie, additional, Azizi, Michel, additional, Jouven, Xavier, additional, and Antignac, Marie, additional
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- 2020
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10. Abstract P137: Socioeconomic Status And Hypertension Control In Sub-saharan Africa: The Multination Eight Study
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Liliane Mfeukeu Kuate, Charles Kouam Kouam, Martin Dèdonougbo Houenassi, Yves N’da Kouakou N’goran, Anastase Dzudie, Pierre-François Plouin, Ibrahim Ali Toure, Kumar Narayanan, Jean Bruno Mipinda, Ibrahima Bara Diop, Abdallahi Sidy Ali, Beatriz Ferreira, Zouwera Sesso, Diane Macquart de Terline, Xavier Jouven, Jean Philippe Empana, Kouadio Euloge Kramoh, Marie Antignac, Suzy Gisèle Kimbally-Kaki, Marie Cécile Perier, Emmanuel Limbole, Méo Stéphane Ikama, Adama Kane, Carol Nhavoto, and Dadhi M. Balde
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Blood pressure ,Sub saharan ,Hypertension control ,business.industry ,Physiology (medical) ,Environmental health ,Medicine ,Social determinants of health ,Cardiology and Cardiovascular Medicine ,business ,Socioeconomic status - Abstract
Introduction: Systemic hypertension is a rapidly growing epidemic in Sub-Saharan Africa. Adequacy of blood pressure(BP) control and the factors influencing it, especially the role of socio-economic status(SES) have not been well studied in this part of the world. Hypothesis: We therefore aimed to quantify the association of SES both at the individual and at the country level with BP control in Sub-Saharan Africa. Methods: We conducted a cross-sectional survey in urban clinics of twelve countries, both low-income and middle-income, in Sub-Saharan Africa. Data were collected on demographics, treatment and standardized BP measures were made among the hypertensive patients attending the clinics. BP control was defined as BP Results: A total of 2198 hypertensive patients (58.4±11.8years; 39.9% male) were included, of whom 1017(46.3%) were from low-income and 1181(53.7%) from middle-income countries. Individual wealth level was low, mid and high in 376(17.6%), 1053(49.2%) and 713(33.3%) patients respectively. Uncontrolled hypertension was present in 1692 patients(77.4%) including 1044(47.7%) with ≥grade 2 hypertension. The proportion of uncontrolled hypertension progressively increased with decreasing level of patient individual wealth, respectively 72.8%, 79.3% and 81.8%(p for trend Conclusions: Low individual wealth was significantly associated with poor hypertension control, especially in low-income countries. Strategies for hypertension control in Sub-Saharan Africa should especially focus on people in the lowest individual wealth groups who also reside in low-income countries.
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- 2018
11. Létalité de l’insuffisance cardiaque au Centre Hospitalier Universitaire de Libreville (CHUL) et facteurs associés
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Mahutondji Christian Allognon, Jean Bruno Mipinda, Francis Ndoume, Emmanuel Ecke Nzengue, and Elsa Ayo Bivigou
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associated factors ,Adult ,Male ,medicine.medical_specialty ,Severity of Illness Index ,Time-to-Treatment ,facteurs associés ,Hospitals, University ,létalité ,Risk Factors ,Diabetes Mellitus ,medicine ,Humans ,Gabon ,Libreville ,Aged ,Retrospective Studies ,Heart Failure ,Gynecology ,business.industry ,Research ,General Medicine ,Middle Aged ,mortality ,Insuffisance cardiaque ,Hospitalization ,Cross-Sectional Studies ,Hypertension ,Female ,business - Abstract
Introduction: l'insuffisance cardiaque (IC) est une cause frequente de deces en Afrique. La presente etude a pour but de determiner le taux de letalite de l'IC et de rechercher les facteurs associes. Methodes: il s'agissait d'une etude retrospective transversale realisee dans le service de cardiologie du CHUL. Elle portait sur l'analyse de dossiers de patients hospitalises pour IC gauche ou globale colliges de Janvier 2014 a Decembre 2016. Resultats: la letalite etait de 10,3%. L'âge moyen des patients decedes (n=64) etait de 57,4 ± 17 ans. Le delai moyen de prise en charge etait de 15± 18 jours et la decompensation faisait suite a un ecart de traitement chez 51,4% des patients decedes. L'association hypertension arterielle et diabete augmentait significativement le risque de deces (OR= 2,2 (1,2-6,6)). Les facteurs associes a la letalite etaient essentiellement: l'hypotension arterielle (OR=6,8(3,2-14,1)), l'insuffisance renale severe (OR=3,5(1,7-7,2)), un index cardio-thoracique superieur a 0,7 (OR= 54,4 (15,3-193,1)), une alteration severe de la fraction d'ejection ventriculaire gauche (OR= 3,0(1,5-5,9)) et un taux eleve de NT-proBNP (OR=3,5(1,2-10,5)). La mortalite augmentait significativement avec le nombre de comorbidites. Les deces etaient dus dans 28,4% des cas a une complication extracardiaque. Conclusion: la letalite de l'IC est liee a la severite et a la precocite des lesions. Le retard de prise en charge et les comorbidites aggravent cette letalite. Le depistage des facteurs de risque et l'education therapeutique pourraient diminuer cette mortalite qui concerne des sujets relativement jeunes.
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- 2018
12. Socioeconomic Status and Hypertension Control in Sub-Saharan Africa: The Multination EIGHT Study (Evaluation of Hypertension in Sub-Saharan Africa)
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Samuel Kingue, Beatriz Ferreira, Roland N'Guetta, Marie Antignac, Ibrahim Ali Toure, Méo Stéphane Ikama, Charles Kouam Kouam, Marie Cécile Perier, Martin Dèdonougbo Houenassi, Suzy Gisèle Kimbally-Kaki, Diane Macquart de Terline, Zouwera Sesso, Pierre-François Plouin, Carol Nhavoto, Adama Kane, Dadhi M. Balde, Dominique Hounsou, Liliane Mfeukeu Kuate, Xavier Jouven, Jean Bruno Mipinda, Anastase Dzudie, Emmanuel Limbole, Jean Philippe Empana, Abdallahi Sidy Ali, Kouadio Euloge Kramoh, Ibrahima Bara Diop, and Kumar Narayanan
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Male ,Sub saharan ,Developing country ,030204 cardiovascular system & hematology ,Odds ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal Medicine ,Prevalence ,Medicine ,Humans ,030212 general & internal medicine ,Socioeconomic status ,Developing Countries ,Poverty ,Africa South of the Sahara ,Aged ,Hypertension control ,business.industry ,Urban Health ,Blood Pressure Determination ,Middle income ,Odds ratio ,Middle Aged ,Blood pressure ,Cross-Sectional Studies ,Socioeconomic Factors ,Hypertension ,Female ,business ,Demography - Abstract
Systemic hypertension is a rapidly growing epidemic in Africa. The role of socioeconomic status on blood pressure control has not been well studied in this part of the world. We, therefore, aimed to quantify the association of socioeconomic status both at the individual and at the country level with blood pressure control in Sub-Saharan Africa. We conducted a cross-sectional survey in urban clinics of 12 countries, both low income and middle income, in Sub-Saharan Africa. Standardized blood pressure measures were made among the hypertensive patients attending the clinics. Blood pressure control was defined as blood pressure P for trend, P for trend, 0.03) and not in middle-income countries ( P for trend, 0.26). In low-income countries, the odds of uncontrolled hypertension increased 1.37-fold (odds ratio, 1.37 [0.99–1.90]) and 1.88-fold (odds ratio, 1.88 [1.10–3.21]) in patients with middle and low individual wealth as compared with high individual wealth. Similarly, the grade of hypertension increased progressively with decreasing level of individual patient wealth ( P for trend
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- 2017
13. Antihypertensive strategies and hypertension control in Sub-Saharan Africa
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Cavagna, Pauline, Stéphane Ikama, Méo, Euloge Kramoh, Kouadio, Laurent Takombe, Jean, Bara Diop, Ibrahima, Ali Toure, Ibrahim, Balde, Dadhi M, Dzudie, Anastase, Ferreira, Beatriz, Houenassi, Martin D, Hounkponou, Murielle, Kane, Adama, Kimbally-Kaki, Suzy G, Kingue, Samuel, Kouam Kouam, Charles, Limbole, Emmanuel, Mfeukeu Kuate, Liliane, Bruno Mipinda, Jean, N’guetta, Roland, Nhavoto, Carol, Marie Damorou, Jean, Sidy Ali, Abdallahi, Gaye, Bamba, Tajeu, Gabriel S, Macquart de Terline, Diane, Cécile Perier, Marie, Azizi, Michel, Jouven, Xavier, and Antignac, Marie
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- 2021
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14. Antihypertensive strategies and hypertension control in Sub-Saharan Africa
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Cavagna, Pauline, Stéphane Ikama, Méo, Euloge Kramoh, Kouadio, Laurent Takombe, Jean, Bara Diop, Ibrahima, Ali Toure, Ibrahim, Balde, Dadhi M, Dzudie, Anastase, Ferreira, Beatriz, Houenassi, Martin D, Hounkponou, Murielle, Kane, Adama, Kimbally-Kaki, Suzy G, Kingue, Samuel, Kouam Kouam, Charles, Limbole, Emmanuel, Mfeukeu Kuate, Liliane, Bruno Mipinda, Jean, N’guetta, Roland, Nhavoto, Carol, Marie Damorou, Jean, Sidy Ali, Abdallahi, Gaye, Bamba, Tajeu, Gabriel S, Macquart de Terline, Diane, Cécile Perier, Marie, Azizi, Michel, Jouven, Xavier, and Antignac, Marie
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- 2024
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15. Electrocardiographic changes during dobutamine stress testing in patients with recent myocardial infarction
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Jean Bruno Mipinda, Patrizio Lancellotti, and Luc Pierard
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,ST elevation ,General Medicine ,Revascularization ,medicine.disease ,Chest pain ,Stenosis ,Internal medicine ,Angioplasty ,medicine ,Cardiology ,Dobutamine ,cardiovascular diseases ,Myocardial infarction ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Electrocardiography ,medicine.drug - Abstract
Objective -The identification of viable but jeopardized myocardium after acute myocardial infarction (AMI) is of great importance for selecting patients who could benefit from a revascularization procedure. The aim of thestudy was to determine the accuracy of the dobutamine stress electrocardiogram (ECG) I) for detecting significant stenosis of the infarct-related artery and 2) for predicting the occurrence of contractile recovery. Methods and results - Ninety-four patients underwent dobutamine stress ECG and quantitative angiography within the first week after AMI. A follow-up resting echocardiogram was obtained in all patients at I month. Significant stenosis of the infarct-related artery was detected in 76 patients and functional recovery occurred in 56 patients. Dobutamine stress induced ST-segment elevation in 44 patients, ST-segment depression in 17 and T-wave normalization in 34. Increase in QT dispersion and dobutamine ST elevation were more sensitive than chest pain and ST-segment depression (79% and 53% vs. 24% and 17%, respectively; p
- Published
- 2004
16. Electrocardiographic changes during dobutamine stress testing in patients with recent myocardial infarction: relation with residual infarct artery stenosis and contractile recovery
- Author
-
Patrizio, Lancellotti, Jean Bruno, Mipinda, and Luc A, Pierard
- Subjects
Male ,Electrocardiography ,Coronary Stenosis ,Electrocardiography, Ambulatory ,Myocardial Infarction ,Humans ,Reproducibility of Results ,Female ,Middle Aged ,Coronary Angiography ,Myocardial Contraction ,Echocardiography, Stress - Abstract
The identification of viable but jeopardized myocardium after acute myocardial infarction (AMI) is of great importance for selecting patients who could benefit from a revascularization procedure. The aim of the study was to determine the accuracy of the dobutamine stress electrocardiogram (ECG) 1) for detecting significant stenosis of the infarct-related artery and 2) for predicting the occurrence of contractile recovery.Ninety-four patients underwent dobutamine stress ECG and quantitative angiography within the first week after AMI. A follow-up resting echocardiogram was obtained in all patients at 1 month. Significant stenosis of the infarct-related artery was detected in 76 patients and functional recovery occurred in 56 patients. Dobutamine stress induced ST-segment elevation in 44 patients, ST-segment depression in 17 and T-wave normalization in 34. Increase in QT dispersion and dobutamine ST elevation were more sensitive than chest pain and ST-segment depression (79% and 53% vs. 24% and 17%, respectively; p0.05) for detecting significant infarct-related artery stenosis. Four independent variables were selected for predicting contractile recovery:or = 20 ms increase in QT dispersion from baseline to low-dose dobutamine (p = 0.00016), dobutamine-induced ST-segment elevation (p = 0.0009), elective angioplasty of the infarct-related artery (p = 0.001) and T-wave normalization (p = 0.005).The analysis of predischarge dobutamine stress ECG is useful for predicting residual stenosis of the infarct-related artery and contractile recovery in the affected area. QT dispersion changes during the test are the most accurate parameter.
- Published
- 2004
17. Significance of dobutamine-induced changes in QT dispersion early after acute myocardial infarction
- Author
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Patrizio Lancellotti, Jean-Bruno Mipinda, A. Bilge, and Luc Pierard
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cell Survival ,Ischemia ,Myocardial Infarction ,QT interval ,Heart Conduction System ,Internal medicine ,Dobutamine ,medicine ,Stress Echocardiography ,Humans ,Myocardial infarction ,Aged ,medicine.diagnostic_test ,business.industry ,Myocardium ,Adrenergic beta-Agonists ,Middle Aged ,medicine.disease ,Pathophysiology ,Atropine ,Anesthesia ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,business ,Electrocardiography ,medicine.drug ,Echocardiography, Stress - Abstract
This study sought to examine the effects of graded dobutamine infusion on QT dispersion early after acute myocardial infarction (AMI) and to investigate the relation of dobutamine-induced changes in QT dispersion to wall motion responses. Seventy-eight patients with a first AMI underwent dobutamine-atropine stress echocardiography 5 +/- 2 days after admission. Contractile reserve was identified in 45 patients and ischemic myocardium in 40. Sixteen patients had persistent akinesia. The best cut-off value of QT dispersion on the baseline electrocardiogram for predicting myocardial viability was 65 ms (sensitivity and specificity of 68%). Dobutamine infusion increased QT dispersion only in patients with viable myocardium (61 +/- 18 to 83 +/- 19 ms, p = 0.003) and/or ischemia (72 +/- 16 to 112 +/- 25 ms, p0.0001). No change was observed in patients with persistent akinesia (84 +/- 10 to 87 +/- 15 ms, p = NS). QT dispersion increased by 22 +/- 12 ms with administration of low-dose dobutamine in patients who had viable myocardium and by 47 +/- 21 ms with administration of low- to high-dose dobutamine in patients with ischemic myocardium. An increase in QT dispersion ofor = 20 ms from at rest to low-dose dobutamine infusion was associated with myocardial viability with a sensitivity of 78% and a specificity of 79%, whereas an increase in QT dispersion ofor = 10 ms from low- to high-dose dobutamine infusion predicted ischemic myocardium with a sensitivity of 85% and a specificity of 82%. In conclusion, (1) low QT dispersion on the baseline electrocardiogram is determined by the presence of viable myocardium, (2) a dobutamine-induced increase in QT dispersion is associated with viable and jeopardized myocardium, and (3) unchanged QT dispersion during dobutamine stress is a simple marker of extensive necrosis.
- Published
- 2001
18. Torsades de pointes au cours d’une anesthésie générale pour césarienne d’urgence dans un contexte de pré-éclampsie
- Author
-
Jean Bruno Mipinda and Adrien Sima Zue
- Subjects
medicine.medical_specialty ,Anesthesiology and Pain Medicine ,business.industry ,Anesthesiology ,Anesthesia ,Pain medicine ,medicine ,General Medicine ,Cesarean delivery ,business ,Fentanyl ,medicine.drug - Published
- 2009
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