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892 results on '"Bruzzese, Dario"'

3. Platelet Inhibition with Ticagrelor 60 mg Versus 90 mg Twice Daily in Elderly Patients with Acute Coronary Syndrome: Rationale and Design of the PLINY THE ELDER Trial

Author

Piccolo, Raffaele, Avvedimento, Marisa, Canonico, Mario Enrico, Gargiulo, Paola, Paolillo, Roberta, Conti, Valeria, Dal Piaz, Fabrizio, Filippelli, Amelia, Morisco, Carmine, Simonetti, Fiorenzo, Leone, Attilio, Marenna, Alessandra, Bruzzese, Dario, Gargiulo, Giuseppe, Stabile, Eugenio, Di Serafino, Luigi, Franzone, Anna, Cirillo, Plinio, and Esposito, Giovanni

Published
2023
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10. High levels of blood circulating immune checkpoint molecules in children with new-onset type 1 diabetes are associated with the risk of developing an additional autoimmune disease

Author

Bruzzaniti, Sara, Piemonte, Erica, Mozzillo, Enza, Bruzzese, Dario, Lepore, Maria Teresa, Carbone, Fortunata, de Candia, Paola, Strollo, Rocky, Porcellini, Antonio, Marigliano, Marco, Maffeis, Claudio, Bifulco, Maurizio, Ludvigsson, Johnny, Franzese, Adriana, Matarese, Giuseppe, and Galgani, Mario

Published
2022
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12. Progressive Depletion of B and T Lymphocytes in Patients with Ataxia Telangiectasia: Results of the Italian Primary Immunodeficiency Network

Author

Cirillo, Emilia, Polizzi, Agata, Soresina, Annarosa, Prencipe, Rosaria, Giardino, Giuliana, Cancrini, Caterina, Finocchi, Andrea, Rivalta, Beatrice, Dellepiane, Rosa M., Baselli, Lucia A., Montin, Davide, Trizzino, Antonino, Consolini, Rita, Azzari, Chiara, Ricci, Silvia, Lodi, Lorenzo, Quinti, Isabella, Milito, Cinzia, Leonardi, Lucia, Duse, Marzia, Carrabba, Maria, Fabio, Giovanna, Bertolini, Patrizia, Coccia, Paola, D’Alba, Irene, Pession, Andrea, Conti, Francesca, Zecca, Marco, Lunardi, Claudio, Bianco, Manuela Lo, Presti, Santiago, Sciuto, Laura, Micheli, Roberto, Bruzzese, Dario, Lougaris, Vassilios, Badolato, Raffaele, Plebani, Alessandro, Chessa, Luciana, and Pignata, Claudio

Published
2022
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17. Assessment of Total, PTEN–, and AR-V7+ Circulating Tumor Cell Count by Flow Cytometry in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Enzalutamide

Author

Di Lorenzo, Giuseppe, Zappavigna, Silvia, Crocetto, Felice, Giuliano, Mario, Ribera, Dario, Morra, Rocco, Scafuri, Luca, Verde, Antonio, Bruzzese, Dario, Iaccarino, Simona, Costabile, Ferdinando, Onofrio, Livia, Viggiani, Martina, Palmieri, Alessandro, De Placido, Pietro, Marretta, Antonella Lucia, Pietroluongo, Erica, Luce, Amalia, Abate, Marianna, Navaeiseddighi, Zahrasadat, Caputo, Vincenzo Francesco, Celentano, Giuseppe, Longo, Nicola, Ferro, Matteo, Morelli, Franco, Facchini, Gaetano, Caraglia, Michele, De Placido, Sabino, and Buonerba, Carlo

Published
2021
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21. Hepatobiliary scintigraphy and kinetic growth rate predict liver failure after ALPPS: a multi-institutional study

Author

Tomassini, Federico, D'Asseler, Yves, Linecker, Michael, Giglio, Mariano C., Castro-Benitez, Carlos, Truant, Stéphanie, Axelsson, Rimma, Olthof, Pim B., Montalti, Roberto, Serenari, Matteo, Chapelle, Thiery, Lucidi, Valerio, Sparrelid, Ernesto, Adam, René, Van Gulik, Thomas, Pruvot, François-René, Clavien, Pierre-Alain, Bruzzese, Dario, Geboes, Karen, and Troisi, Roberto I.

Published
2020
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23. Validation of the echocardiographic assessment of epicardial adipose tissue thickness at the Rindfleisch fold for the prediction of coronary artery disease

Author

Parisi, Valentina, Petraglia, Laura, Formisano, Roberto, Caruso, Aurelio, Grimaldi, Maria G., Bruzzese, Dario, Grieco, Fabrizio V., Conte, Maddalena, Paolillo, Stefania, Scatteia, Alessandra, Dellegrottaglie, Santo, Iavazzo, Annarita, Campana, Pasquale, Pilato, Emanuele, Lancellotti, Patrizio, Russo, Vincenzo, Attena, Emilio, Filardi, Pasquale P., and Leosco, Dario

Published
2020
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24. Laparoscopic gynecological surgery under minimally invasive anesthesia: a prospective cohort study.

Author

Giampaolino, Pierluigi, primary, Mercorio, Antonio, additional, Corte, Luigi Della, additional, Bruzzese, Dario, additional, Coviello, Antonio, additional, Grasso, Giovanna, additional, Piano, Anna Claudia Del, additional, Candice, Agostino, additional, Sardo, Attilio Di Spiezio, additional, Servillo, Giuseppe, additional, and Bifulco, Giuseppe, additional

Published
2024
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25. Isolated Valve Amyloid Deposition in Aortic Stenosis: Potential Clinical and Pathophysiological Relevance

Author

Conte, Maddalena, primary, Poggio, Paolo, additional, Monti, Maria, additional, Petraglia, Laura, additional, Cabaro, Serena, additional, Bruzzese, Dario, additional, Comentale, Giuseppe, additional, Caruso, Aurelio, additional, Grimaldi, Mariagabriella, additional, Zampella, Emilia, additional, Gencarelli, Annarita, additional, Cervasio, Maria Rosaria, additional, Cozzolino, Flora, additional, Monaco, Vittoria, additional, Myasoedova, Veronika, additional, Valerio, Vincenza, additional, Ferro, Adele, additional, Insabato, Luigi, additional, Bellino, Michele, additional, Galasso, Gennaro, additional, Graziani, Francesca, additional, Pucci, Pietro, additional, Formisano, Pietro, additional, Pilato, Emanuele, additional, Cuocolo, Alberto, additional, Perrone Filardi, Pasquale, additional, Leosco, Dario, additional, and Parisi, Valentina, additional

Published
2024
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35. Findings from the Use of Spinal Anesthesia in the Laparoscopic Treatment of Extrauterine Pregnancy: Could It Represent an Alternative to General Anesthesia?

Author

Della Corte, Luigi, primary, Guarino, Maria Chiara, additional, Dell'Aquila, Michela, additional, Ascione, Mario, additional, Guerra, Serena, additional, De Rosa, Rossella, additional, Del Piano, Annaclaudia, additional, Bruzzese, Dario, additional, Bifulco, Giuseppe, additional, and Giampaolino, Pierluigi, additional

Published
2023
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36. Impact of vasodilators on diuretic response in patients with congestive heart failure: a mechanistic trial of cimlanod (BMS‐986231)

Author

Pellicori, Pierpaolo, primary, Cleland, John G.F., additional, Borentain, Maria, additional, Taubel, Jorg, additional, Graham, Fraser, additional, Khan, Javed, additional, Bruzzese, Dario, additional, Kessler, Paul, additional, McMurray, John J.V., additional, Voors, Adriaan A., additional, O'Connor, Christopher M., additional, Teerlink, John R., additional, and Felker, G. Michael, additional

Published
2023
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37. Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents in the Mediterranean Region of Europe

Author

Kafritsa, Panayota, Brusa, Sandra, Campanozzi, Angelo, Romano, Claudio, Salvatore, Silvia, Kotzakioulafi, Evelina, Barrio, Josefa, Cilleruelo, Maria Luz, Juste, Mercedes, Gutiérrez-Junquera, Carolina, Trbojević, Tena, Ivković, Lana, Scarpato, Elena, Kolacek, Sanja, Jojkic-Pavkov, Danijela, Konjik, Vlatka, Živković, Nataša, Roman, Enriqueta, Kostovski, Aco, Zdraveska, Nikolina, Altamimi, Eyad, Papadopoulou, Alexandra, Karagiozoglou-Lampoudi, Thomai, Shamir, Raanan, Bar Lev, Michal Rozenfeld, Koleilat, Aziz, Mneimneh, Sirin, Bruzzese, Dario, Leis, Rosaura, and Staiano, Annamaria

Published
2018
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38. Lack of efficacy of Lactobacillus GG in reducing pulmonary exacerbations and hospital admissions in children with cystic fibrosis: A randomised placebo controlled trial

Author

Bruzzese, Eugenia, Raia, Valeria, Ruberto, Eliana, Scotto, Riccardo, Giannattasio, Antonietta, Bruzzese, Dario, Cavicchi, Maria Cristina, Francalanci, Michela, Colombo, Carla, Faelli, Nadia, Daccò, Valeria, Magazzù, Giuseppe, Costa, Stefano, Lucidi, Vincenzina, Majo, Fabio, and Guarino, Alfredo

Published
2018
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39. Human epidermal growth factor receptor 2 dual blockade with trastuzumab and pertuzumab in real life: Italian clinical practice versus the CLEOPATRA trial results

Author

De Placido, Sabino, Giuliano, Mario, Schettini, Francesco, Von Arx, Claudia, Buono, Giuseppe, Riccardi, Ferdinando, Cianniello, Daniela, Caputo, Roberta, Puglisi, Fabio, Bonotto, Marta, Fabi, Alessandra, Bilancia, Domenico, Ciccarese, Mariangela, Lorusso, Vito, Michelotti, Andrea, Bruzzese, Dario, Veneziani, Bianca Maria, Locci, Mariavittoria, De Laurentiis, Michelino, and Arpino, Grazia

Published
2018
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41. Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression

Author

Galgani, Mario, Nugnes, Rosa, Bruzzese, Dario, Perna, Francesco, De Rosa, Veronica, Procaccini, Claudio, Mozzillo, Enza, Cilio, Corrado M, Larsson, Helena Elding, Lernmark, Åke, La Cava, Antonio, Franzese, Adriana, and Matarese, Giuseppe

Subjects
Diabetes, Autoimmune Disease, Nutrition, Clinical Research, Pediatric, Detection, screening and diagnosis, 2.1 Biological and endogenous factors, 4.1 Discovery and preclinical testing of markers and technologies, Aetiology, Metabolic and endocrine, Autoimmunity, Biomarkers, Child, Diabetes Mellitus, Type 1, Disease Progression, Flow Cytometry, Humans, Insulin-Secreting Cells, Monitoring, Immunologic, Prognosis, T-Lymphocytes, Medical and Health Sciences, Endocrinology & Metabolism
Abstract

Type 1 diabetes is characterized by autoimmune destruction of pancreatic β-cells in genetically susceptible individuals. Triggers of islet autoimmunity, time course, and the precise mechanisms responsible for the progressive β-cell failure are not completely understood. The recent escalation of obesity in affluent countries has been suggested to contribute to the increased incidence of type 1 diabetes. Understanding the link between metabolism and immune tolerance could lead to the identification of new markers for the monitoring of disease onset and progression. We studied several immune cell subsets and factors with high metabolic impact as markers associated with disease progression in high-risk subjects and type 1 diabetic patients at onset and at 12 and 24 months after diagnosis. A multiple correlation matrix among different parameters was evaluated statistically and assessed visually on two-dimensional graphs. Markers to predict residual β-cell function up to 1 year after diagnosis were identified in multivariate logistic regression models. The meta-immunological profile changed significantly over time in patients, and a specific signature that was associated with worsening disease was identified. A multivariate logistic regression model measuring age, BMI, fasting C-peptide, number of circulating CD3(+)CD16(+)CD56(+) cells, and the percentage of CD1c(+)CD19(-)CD14(-)CD303(-) type 1 myeloid dendritic cells at disease onset had a significant predictive value. The identification of a specific meta-immunological profile associated with disease status may contribute to our understanding of the basis of diabetes progression.

Published
2013

43. Incidence of fatigue and low-dose corticosteroid use in prostate cancer patients receiving systemic treatment: a meta-analysis of randomized controlled trials

Author

Ferro, Matteo, Di Lorenzo, Giuseppe, de Cobelli, Ottavio, Bruzzese, Dario, Pignataro, Piero, Borghesi, Marco, Musi, Gennaro, Vartolomei, Mihai Dorin, Cosimato, Vincenzo, Serino, Alessandro, Ieluzzi, Vincenzo, Terracciano, Daniela, Damiano, Rocco, Cantiello, Francesco, Mistretta, Francesco Alessandro, Muto, Matteo, Lucarelli, Giuseppe, De Placido, Pietro, and Buonerba, Carlo

Published
2019
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48. Impact of vasodilators on diuretic response in patients with congestive heart failure: A mechanistic trial of cimlanod (BMS‐986231).

Author

Pellicori, Pierpaolo, Cleland, John G.F., Borentain, Maria, Taubel, Jorg, Graham, Fraser J., Khan, Javed, Bruzzese, Dario, Kessler, Paul, McMurray, John J.V., Voors, Adriaan A., O'Connor, Christopher M., Teerlink, John R., and Felker, G. Michael

Subjects
FUROSEMIDE, BRAIN natriuretic factor, CONGESTIVE heart failure, HEART failure patients, SYSTOLIC blood pressure, DIURETICS
Abstract

Aim: To investigate the effects of Cimlanod, a nitroxyl donor with vasodilator properties, on water and salt excretion after an administration of an intravenos bolus of furosemide. Methods and results: In this randomized, double‐blind, mechanistic, crossover trial, 21 patients with left ventricular ejection fraction <45%, increased plasma concentrations of N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) and receiving loop diuretics were given, on separate study days, either an 8 h intravenous (IV) infusion of cimlanod (12 μg/kg/min) or placebo. Furosemide was given as a 40 mg IV bolus four hours after the start of infusion. The primary endpoint was urine volume in the 4 h after the bolus of furosemide during infusion of cimlanod compared with placebo. Median NT‐proBNP at baseline was 1487 (interquartile range: 847–2665) ng/L. Infusion of cimlanod increased cardiac output and reduced blood pressure without affecting cardiac power index consistent with its vasodilator effects. Urine volume in the 4 h post‐furosemide was lower with cimlanod (1032 ± 393 ml) versus placebo (1481 ± 560 ml) (p = 0.002), as were total sodium excretion (p = 0.004), fractional sodium excretion (p = 0.016), systolic blood pressure (p < 0.001), estimated glomerular filtration rate (p = 0.012), and haemoglobin (p = 0.010), an index of plasma volume expansion. Conclusions: For patients with heart failure and congestion, vasodilatation with agents such as cimlanod reduces the response to diuretic agents, which may offset any benefit from acute reductions in cardiac preload and afterload. [ABSTRACT FROM AUTHOR]

Published
2024
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49. Findings from the Use of Spinal Anesthesia in the Laparoscopic Treatment of Extrauterine Pregnancy: Could It Represent an Alternative to General Anesthesia?

Author

Della Corte, Luigi, Guarino, Maria Chiara, Dell'Aquila, Michela, Ascione, Mario, Guerra, Serena, De Rosa, Rossella, Del Piano, Annaclaudia, Bruzzese, Dario, Bifulco, Giuseppe, and Giampaolino, Pierluigi

Subjects
ECTOPIC pregnancy, SALPINGECTOMY, SPINAL anesthesia, GENERAL anesthesia, MINIMALLY invasive procedures, LAPAROSCOPIC surgery
Abstract

Introduction: Minimally invasive procedures performed in laparoscopy, such as salpingectomy for ectopic pregnancy, can be combined with a minimally invasive anesthesia. The aim of this study was to assess the feasibility and the intraoperative and postoperative outcomes of laparoscopic surgery for ectopic pregnancy under spinal anesthesia (SA) compared to general anesthesia (GA) from the point of view of the surgeon, anesthesiologist, and patient. Methods: A retrospective cohort study was performed at DAI Materno Infantile of AOU Federico II of Naples, analyzing all medical records of women who met the inclusion criteria between April 2020 and April 2023. Eighty-two women (35 under SA in group A and 47 under GA in group B) undergone elective or emergency laparoscopic salpingectomy for ectopic tubal or ovarian pregnancy were included. Results: Patients in group A reported less pain at 0 h (adjusted mean difference: −1.5; 95% CI: −2.3 to −0.7; p < 0.001) and after 6 h (adjusted mean difference: −1.1; 95% CI: −2.0 to −0.3; p = 0.01) while no statistically significant differences between the two groups at 12 and 24 h after surgery. No differences were observed among the type of analgesic and during the postoperative observation time, except for paracetamol at 0 h in group B. A faster resumption of bowel motility, patient's mobilization, and a shorter hospital stay were observed in group A compared to group B. Also greater odds of returning faster to daily activities emerged in group A (adjusted OR: 5.39; 95% CI: 1.77–16.37). A greater number of patients in group A were satisfied with the entire procedure compared to those of group B (33 [94.3%] vs. 37 [78.7%]). The general surgeon satisfaction was always very good or excellent in group A. Finally, all surgical steps were well tolerated in group A. Conclusion: In specific settings, SA is a feasible and safe procedure for the laparoscopic treatment of ectopic pregnancy. [ABSTRACT FROM AUTHOR]

Published
2024
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50. Population Trends in Rates of Percutaneous Coronary Revascularization for Acute Coronary Syndromes Associated With the COVID-19 Outbreak

Author

Piccolo, Raffaele, Bruzzese, Dario, Mauro, Ciro, Aloia, Antonio, Baldi, Cesare, Boccalatte, Marco, Bottiglieri, Giuseppe, Briguori, Carlo, Caiazzo, Gianluca, Calabrò, Paolo, Cappelli-Bigazzi, Maurizio, De Simone, Ciro, Di Lorenzo, Emilio, Golino, Paolo, Monda, Vittorio, Perrotta, Rocco, Quaranta, Gaetano, Russolillo, Enrico, Scherillo, Marino, Tesorio, Tullio, Tuccillo, Bernardino, Valva, Giuseppe, Villari, Bruno, Tarantini, Giuseppe, Varricchio, Attilio, and Esposito, Giovanni

Published
2020
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