1. HIV risk behavior profiles among men who have sex with men interested in donating blood: Findings from the Assessing Donor Variability and New Concepts in Eligibility study.
- Author
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Custer, Brian, Whitaker, Barbee, Pollack, Lance, Buccheri, Renata, Bruhn, Roberta, Crowder, Lauren, Stramer, Susan, Reik, Rita, Pandey, Suchitra, Stone, Mars, Di Germanio, Clara, Buchacz, Kate, Eder, Anne, Lu, Yun, Forshee, Richard, Anderson, Steven, and Marks, Peter
- Subjects
donors ,regulatory and QA ,transfusion-transmitted disease - HIV ,Humans ,Male ,Adult ,HIV Infections ,Blood Donors ,Homosexuality ,Male ,Cross-Sectional Studies ,Adolescent ,Risk-Taking ,Young Adult ,Pre-Exposure Prophylaxis ,Sexual Behavior ,Surveys and Questionnaires - Abstract
BACKGROUND: Individual risk assessment allows donors to be evaluated based on their own behaviors. Study objectives were to assess human immunodeficiency virus (HIV) risk behaviors in men who have sex with men (MSM) and estimate the proportion of the study population who would not be deferred for higher risk HIV sexual behaviors. STUDY DESIGN AND METHODS: Cross-sectional survey and biomarker assessment were conducted in eight U.S. cities. Participants were sexually active MSM interested in blood donation aged 18-39 years, assigned male sex at birth. Participants completed surveys during two study visits to define eligibility, and self-reported sexual and HIV prevention behaviors. Blood was drawn at study visit 1 and tested for HIV and the presence of tenofovir, one of the drugs in oral HIV pre-exposure prophylaxis (PrEP). Associations were assessed between HIV infection status or HIV PrEP use and behaviors, including sex partners, new partners, and anal sex. RESULTS: A total of 1566 MSM completed the visit 1 questionnaire and blood draw and 1197 completed the visit 2 questionnaire. Among 1562 persons without HIV, 789 (50.4%) were not taking PrEP. Of those not taking PrEP, 66.2% reported one sexual partner or no anal sex and 69% reported no new sexual partners or no anal sex with a new partner in the past 3 months. CONCLUSION: The study found that questions were able to identify sexually active, HIV-negative MSM who report lower risk sexual behaviors. About a quarter of enrolled study participants would be potentially eligible blood donors using individual risk assessment questions.
- Published
- 2023