448 results on '"Buckner, Frederick S."'
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2. Leishmania donovani tyrosyl-tRNA synthetase structure in complex with a tyrosyl adenylate analog and comparisons with human and protozoan counterparts
3. Discovery of N-(2-aminoethyl)-N-benzyloxyphenyl benzamides: New potent Trypanosoma brucei inhibitors
4. Structure-Based Design of Submicromolar, Biologically Active Inhibitors of Trypanosomatid Glyceraldehyde-3-Phosphate Dehydrogenase
5. Structure-guided design of novel Trypanosoma brucei Methionyl-tRNA synthetase inhibitors
6. Windows into leishmaniasis epidemiology in the United States: September 2021 through August 2022
7. Identification of Potent Inhibitors of the Trypanosoma brucei Methionyl-tRNA Synthetase via High-Throughput Orthogonal Screening
8. Sterol 14-Demethylase Inhibitors for Trypanosoma cruzi Infections
9. Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
10. Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design
11. Protein Prenylation in Trypanosomatids : A New Piggy-Back Medicinal Chemistry Target for the Development of Agents Against Tropical Diseases
12. Recent highlights in anti-protozoan drug development and resistance research
13. Recent developments in sterol 14-demethylase inhibitors for Chagas disease
14. Chagas Disease
15. List of Contributors
16. Leishmaniasis
17. Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection
18. The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer
19. Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase
20. Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate
21. Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs
22. The Crystal Structure and Activity of a Putative Trypanosomal Nucleoside Phosphorylase Reveal It to be a Homodimeric Uridine Phosphorylase
23. Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica
24. Delusional parasitosis: six-year experience with 23 consecutive cases at an academic medical center
25. Prediction of protein crystallization outcome using a hybrid method
26. Buffer Optimization of Thermal Melt Assays of Plasmodium Proteins for Detection of Small-Molecule Ligands
27. Cytomegalovirus Disease of the Gastrointestinal Tract in Patients without AIDS
28. The Tryp and the Pendulum
29. Screening a fragment cocktail library using ultrafiltration
30. Protein geranylgeranyltransferase-I of Trypanosoma cruzi
31. Structures of Substrate- and Inhibitor-Bound Adenosine Deaminase from a Human Malaria Parasite Show a Dramatic Conformational Change and Shed Light on Drug Selectivity
32. Heterologous expression of L. major proteins in S. cerevisiae: a test of solubility, purity, and gene recoding
33. Case Report: Miltefosine Failure and Spontaneous Resolution of Cutaneous Leishmaniasis braziliensis
34. C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins
35. Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection
36. Early Stages of Drug Discovery in an Academic Institution and Involvement of Pharma for Advancing Promising Leads
37. A new chemotype with promise against Trypanosoma cruzi
38. Experimental Chemotherapy and Approaches to Drug Discovery for Trypanosoma cruzi Infection
39. Thematic review series: Lipid Posttranslational Modifications. Fighting parasitic disease by blocking protein farnesylation
40. Heterologous expression of proteins from Plasmodium falciparum: Results from 1000 genes
41. Immunological Aspects of Cardiac Disease
42. Structural Genomics of Pathogenic Protozoa: an Overview
43. Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases
44. Clinical Features and Outcomes of 105 Hospitalized Patients With COVID-19 in Seattle, Washington
45. Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone
46. Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors
47. Confirmation of Chagas' cardiomyopathy following heart transplantation
48. Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
49. Setting Our Sights on Infectious Diseases
50. Leishmania inactivation in human pheresis platelets by a psoralen (amotosalen HCl) and long-wavelength ultraviolet irradiation
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