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298 results on '"Bucolo, Maide"'

9. Quantitative analysis of spatial irregularities in RBCs flows

Author

Cairone, Fabiana, Mirabella, Daniela, Cabrales, Pedro J, Intaglietta, Marcos, and Bucolo, Maide

Subjects
Two-phase microfluidics, DPIV analysis, Velocity gradients, Nonlinear indicators, Mathematical Sciences, Information and Computing Sciences, Engineering, Mathematical Physics
Published
2018

10. Multijump Resonance with Chua’s Circuit

Author

Bucolo, Maide, Buscarino, Arturo, Famoso, Carlo, Fortuna, Luigi, Frasca, Mattia, Lacarbonara, Walter, editor, Balachandran, Balakumar, editor, Ma, Jun, editor, Tenreiro Machado, J. A., editor, and Stepan, Gabor, editor

Published
2020
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29. 3D-Printed Micro-Optofluidic Slug Flow Detector

Author

Stella, Giovanna, Saitta, Lorena, Moscato, Samuele, Cicala, Gianluca, and Bucolo, Maide

Abstract

Non-Newtonian fluids analysis in microdevices is challenging both in biological and chemical applications. In this context, the flow velocity evaluation is crucial. This work presents a portable and disposable micro-optofluidic detector ( $\mu $ OFD), in which microoptical and microfluidic components are integrated and used for the real-time characterization of a sequenced flow generated by two immiscible fluids, called slug flow. The 3D-printed approach was chosen for the device fabrication, being simple, flexible, fast, and low-cost, and for the possibility of exploring wider channel geometries as compared to soft lithography. In the micro optofluidic detector, the light interacts with the flow in two observation points, 1 mm apart from each other, placed along the microchannel at 26 mm far from the T-junction. The optical signal variations, correlated with the fluids’ optical properties, were used for real-time tracking of slug frequency passage, velocity, and length by an ad hoc signal processing procedure. Two $\mu $ OFD prototypes were presented. One prototype was entirely made in poly-dimethyl-siloxane (PDMS), while in the second, the microoptical component was made of VeroClear and the microfluidic part in PDMS. Both prototypes were successfully characterized in different hydrodynamic conditions as proof of concept of their validity as flow velocity detectors. The advantage of realizing, by using a low-cost and easy-to-use fabrication process, a micro-optofluidic device that embeds the optical monitoring elements and the microchannels, without constraints on the localization of the observation point and microchannel height, opens the way to the design of a great variety of lab-on-a-chip (LOC) microdevices for complex fluids investigation.

Published
2024
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34. A Regression Approach to Model Refractive Index Measurements of Novel 3D Printable Photocurable Resins for Micro-Optofluidic Applications.

Author

Saitta, Lorena, Cutuli, Emanuela, Celano, Giovanni, Tosto, Claudio, Stella, Giovanna, Cicala, Gianluca, and Bucolo, Maide

Subjects
REFRACTIVE index, OPTICAL measurements, REGRESSION analysis, LIGHT transmission, MICROFLUIDIC devices
Abstract

In this work, a quadratic polynomial regression model was developed to aid practitioners in the determination of the refractive index value of transparent 3D printable photocurable resins usable for micro-optofluidic applications. The model was experimentally determined by correlating empirical optical transmission measurements (the dependent variable) to known refractive index values (the independent variable) of photocurable materials used in optics, thus obtaining a related regression equation. In detail, a novel, simple, and cost-effective experimental setup is proposed in this study for the first time for collecting the transmission measurements of smooth 3D printed samples (roughness ranging between 0.04 and 2 μm). The model was further used to determine the unknown refractive index value of novel photocurable resins applicable in vat photopolymerization (VP) 3D printing techniques for manufacturing micro-optofluidic (MoF) devices. In the end, this study proved how knowledge of this parameter allowed us to compare and interpret collected empirical optical data from microfluidic devices made of more traditional materials, i.e., Poly(dimethylsiloxane) (PDMS), up to novel 3D printable photocurable resins suitable for biological and biomedical applications. Thus, the developed model also provides a quick method to evaluate the suitability of novel 3D printable resins for MoF device fabrication within a well-defined range of refractive index values (1.56; 1.70). [ABSTRACT FROM AUTHOR]

Published
2023
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