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2. Negative Emotions in End-Stage Renal Disease: Are Anxiety Symptoms Related to Levels of Circulating Catecholamines?

Author

Buemi, Michele, Bruno, Antonio, Cordova, Francesca, Currò, Veronica, Di Mauro, Eleonora, Santoro, Domenico, and Cernaro, Valeria

Subjects
Chronic kidney failure -- Diagnosis -- Care and treatment, Dopamine, Psychology and mental health
Abstract

The purpose of this study was to assess depression and anxiety levels and possible correlations with levels of circulating catecholamines in maintenance hemodialysis (MHD) and Conservative care (CC) ERSD patients. Eighty ESRD patients, forty treated by MHD and forty by CC, were included in the study. Circulating catecholamines concentrations were measured; all subjects were assessed by Hamilton Rating Scale for Depression, Hamilton Rating Scale for Anxiety, Self-Rating Depression Scale, and Self-Rating Anxiety Scale. Statistical analysis showed significant differences in Noradrenaline (p < 0.0001), higher in the CC group, and Dopamine (p = 0.002), higher in MHD subjects. Moreover, significant differences were documented regarding the anxiety variables (HRSA: p = 0.007; SAS: p = 0.007), all higher in CC group; no significant differences were documented on depression variables. Finally, linear regression analysis indicated that only noradrenaline was a strongest predictor of anxiety (HRSA: p = 0.003; SAS: p < 0.0001). ESRD patients showed a heightened vulnerability to anxiety. Given the concerns with pharmacologic treatment of emotional disturbances in patients with ESRD, the priority should be given to psychological interventions and preventive approaches aimed to address the early appearance of anxiety symptoms., Author(s): Michele Buemi [sup.1], Antonio Bruno [sup.2], Francesca Cordova [sup.2], Veronica Currò [sup.2], Eleonora Di Mauro [sup.1], Domenico Santoro [sup.1], Valeria Cernaro [sup.1], Gianluca Pandolfo [sup.2], Maria Rosaria Anna Muscatello [...]

Published
2020
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9. Management of dyslipidaemia in patients with chronic kidney disease: a position paper endorsed by the Italian Society of Nephrology

Author

Pontremoli, Roberto, Bellizzi, Vincenzo, Bianchi, Stefano, Bigazzi, Roberto, Cernaro, Valeria, Del Vecchio, Lucia, De Nicola, Luca, Leoncini, Giovanna, Mallamaci, Francesca, Zoccali, Carmine, and Buemi, Michele

Abstract

Chronic kidney disease (CKD) represents a major public health issue worldwide and entails a high burden of cardiovascular events and mortality. Dyslipidaemia is common in patients with CKD and it is characterized by a highly atherogenic profile with relatively low levels of HDL-cholesterol and high levels of triglyceride and oxidized LDL-cholesterol. Overall, current literature indicates that lowering LDL-cholesterol is beneficial for preventing major atherosclerotic events in patients with CKD and in kidney transplant recipients while the evidence is less clear in patients on dialysis. Lipid lowering treatment is recommended in all patients with stage 3 CKD or worse, independently of baseline LDL-cholesterol levels. Statin and ezetimibe are the cornerstones in the management of dyslipidaemia in patients with CKD, however alternative and emerging lipid-lowering therapies may acquire a central role in near future. This position paper endorsed by the Italian Society of Nephrology aims at providing useful information on the topic of dyslipidaemia in CKD and at assisting decision making in the management of these patients.

Published
2024
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32. MO139INDOLE-3-ACETIC ACID CORRELATES WITH MONOCYTE TO HIGH-DENSITY LIPOPROTEIN (HDL) RATIO (MHR) IN CHRONIC KIDNEY DISEASE (CKD) PATIENTS AND MAY BE EFFICIENTLY REMOVED BY ACETATE-FREE BIOFILTRATION

Author

Cernaro, Valeria, primary, Calabrese, Vincenzo, additional, Loddo, Saverio, additional, Corsaro, Roberta, additional, Macaione, Vincenzo, additional, Ferlazzo, Valentina Teresa, additional, Cigala, Rosalia Maria, additional, Crea, Francesco, additional, De Stefano, Concetta, additional, Gembillo, Guido, additional, Romeo, Adolfo, additional, Longhitano, Elisa, additional, Santoro, Domenico, additional, Buemi, Michele, additional, and Benvenga, Salvatore, additional

Published
2021
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37. EXPERIMENTAL ISCHEMIA

Author

Cernaro, Valeria, Sfacteria, Alessandra, Lucisano, Silvia, Lupica, Rosaria, Bruzzese, Anna Maria, Aloisi, Carmela, Montuori, Francesca, Lorenzano, Giuseppina, Visconti, Luca, and Buemi, Michele

Published
2014

49. Research update for articles published in EJCI in 2009

Author

Abed, Majed, Adlbrecht, Christopher, Amado Señarís, Jose Antonio, Amighi, Jasmin, Ankersmit, Hendrik J., de Berrazueta, Jose R., Bobbioni-Harsch, Elisabetta, Boyle, Kathryn, Buechler, Christa, Buemi, Michele, Cernaro, Valeria, Chang, Je-Ken, Chen, Chung-Hwan, Cheng, Wen-Ping, Cuocolo, Alberto, Dullaart, Robin P. F., Ghafourifar, Pedram, Guzik, Przemyslaw, Hoffmann, Michael M., Jurado, Jeroni, Kytö, Ville, Lang, Florian, Lichtenauer, Michael, Lin, Zu-Yau, Minami, Yoshitaka, Montero, David, Mookadam, Farouk, Nicolai, Emanuele, Pacher, Richard, Rahimian, Reza, Satoh, Mamoru, Saukko, Pekka, Selzer, Edgar, Shyu, Kou-Gi, Sztajzel, Juan, Vinet, Agnès, Walter, Martin A., Willmann, Michael, Winkler, Karl, Wykretowicz, Andrzej, Köker, Mustafa Y., and Ybarra, Juan

Published
2011
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