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21 results on '"Bunn, Diane K."'

10. Effectiveness of interventions to indirectly support food and drink intake in people with dementia: Eating and Drinking Well IN dementiA (EDWINA) systematic review

Author

Bunn, Diane K., primary, Abdelhamid, Asmaa, additional, Copley, Maddie, additional, Cowap, Vicky, additional, Dickinson, Angela, additional, Howe, Amanda, additional, Killett, Anne, additional, Poland, Fiona, additional, Potter, John F., additional, Richardson, Kate, additional, Smithard, David, additional, Fox, Chris, additional, and Hooper, Lee, additional

Published
2016
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11. Which Frail Older People Are Dehydrated? The UK DRIE Study

Author

Hooper, Lee, primary, Bunn, Diane K., additional, Downing, Alice, additional, Jimoh, Florence O., additional, Groves, Joyce, additional, Free, Carol, additional, Cowap, Vicky, additional, Potter, John F., additional, Hunter, Paul R., additional, and Shepstone, Lee, additional

Published
2015
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12. Diagnostic accuracy of calculated serum osmolarity to predict dehydration in older people: adding value to pathology laboratory reports

Author

Hooper, Lee, primary, Abdelhamid, Asmaa, additional, Ali, Adam, additional, Bunn, Diane K, additional, Jennings, Amy, additional, John, W Garry, additional, Kerry, Susan, additional, Lindner, Gregor, additional, Pfortmueller, Carmen A, additional, Sjöstrand, Fredrik, additional, Walsh, Neil P, additional, Fairweather-Tait, Susan J, additional, Potter, John F, additional, Hunter, Paul R, additional, and Shepstone, Lee, additional

Published
2015
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15. Reduction of long-term disability in inflammatory polyarthritis by early and persistent suppression of joint inflammation: Results from the norfolk arthritis register

Author

Scirè, C, Verstappen, S, Mirjafari, H, Bunn, D, Lunt, M, Montecucco, C, Bruce, I, Symmons, D, Scirè, Carlo A., Verstappen, Suzanne M. M., Mirjafari, Hoda, Bunn, Diane K., Lunt, Mark, Montecucco, Carlomaurizio, Bruce, Ian N., Symmons, Deborah P. M., Scirè, C, Verstappen, S, Mirjafari, H, Bunn, D, Lunt, M, Montecucco, C, Bruce, I, Symmons, D, Scirè, Carlo A., Verstappen, Suzanne M. M., Mirjafari, Hoda, Bunn, Diane K., Lunt, Mark, Montecucco, Carlomaurizio, Bruce, Ian N., and Symmons, Deborah P. M.

Abstract

Objective: To test the predictive ability of remission in terms of long-term disability in patients with recent-onset inflammatory polyarthritis (IP). Methods: Consecutive patients with early IP, recruited between 1990 and 1994 (first cohort) and 2000 and 2004 (second cohort), were included in this study. Remission was defined as the absence of clinically detectable joint inflammation on a 51-joint count. In additional analyses, less stringent definitions of remission were used based on the 40-and 28-joint counts. Remission was assessed at 1, 2, and 3 years after inclusion. A 5-year Health Assessment Questionnaire score ≥1 (moderate disability) was chosen as the primary outcome measure. Results: A total of 841 and 498 patients from the first and second cohorts, respectively, completed 5 years of followup. In the first cohort, patients with at least 1 episode of remission had lower odds of 5-year disability (odds ratio [OR] 0.26, 95% confidence interval [95% CI] 0.17-0.41). The number of times in remission correlated with the odds of disability, with a mean decrease in the probability of disability of ∼64% for each additional time point in remission (OR 0.38, 95% CI 0.28-0.52). The time until first remission was not associated with functional disability. Remission according to less stringent criteria showed a weaker protection against future disability. Similar results were found in the second cohort. Conclusion: Patients with IP achieving a state of sustained remission early are less likely to show long-term deterioration of function compared with patients who do not achieve remission. The most persistent remission under the most stringent definition of remission has the lowest probability of long-term disability. © 2011, American College of Rheumatology.

Published
2011

16. Which Frail Older People Are Dehydrated? The UK DRIE Study.

Author

Hooper, Lee, Bunn, Diane K., Downing, Alice, Jimoh, Florence O., Groves, Joyce, Free, Carol, Cowap, Vicky, Potter, John F., Hunter, Paul R., and Shepstone, Lee

Subjects
*DEHYDRATION, *OLDER people, *OSMOLAR concentration, *DEMENTIA, *DIABETES, *GERIATRIC assessment, *FRAIL elderly, *LONG-term health care, *RESEARCH funding, *DISEASE prevalence, *CROSS-sectional method
Abstract

Background: Water-loss dehydration in older people is associated with increased mortality and disability. We aimed to assess the prevalence of dehydration in older people living in UK long-term care and associated cognitive, functional, and health characteristics.Methods: The Dehydration Recognition In our Elders (DRIE) cohort study included people aged 65 or older living in long-term care without heart or renal failure. In a cross-sectional baseline analysis, we assessed serum osmolality, previously suggested dehydration risk factors, general health, markers of continence, cognitive and functional health, nutrition status, and medications. Univariate linear regression was used to assess relationships between participant characteristics and serum osmolality, then associated characteristics entered into stepwise backwards multivariate linear regression.Results: DRIE included 188 residents (mean age 86 years, 66% women) of whom 20% were dehydrated (serum osmolality >300 mOsm/kg). Linear and logistic regression suggested that renal, cognitive, and diabetic status were consistently associated with serum osmolality and odds of dehydration, while potassium-sparing diuretics, sex, number of recent health contacts, and bladder incontinence were sometimes associated. Thirst was not associated with hydration status.Conclusions: DRIE found high prevalence of dehydration in older people living in UK long-term care, reinforcing the proposed association between cognitive and renal function and hydration. Dehydration is associated with increased mortality and disability in older people, but trials to assess effects of interventions to support healthy fluid intakes in older people living in residential care are needed to enable us to formally assess causal direction and any health benefits of increasing fluid intakes. [ABSTRACT FROM AUTHOR]

Published
2016
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17. Using lifestyle factors to identify individuals at higher risk of inflammatory polyarthritis (results from the European Prospective Investigation of Cancer-Norfolk and the Norfolk Arthritis Register—the EPIC-2-NOAR Study)

Author

Lahiri, Manjari, primary, Luben, Robert N, additional, Morgan, Catharine, additional, Bunn, Diane K, additional, Marshall, Tarnya, additional, Lunt, Mark, additional, Verstappen, Suzanne M M, additional, Symmons, Deborah P M, additional, Khaw, Kay-Tee, additional, Wareham, Nick, additional, and Bruce, Ian N, additional

Published
2013
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21. Association of functional outcome with both personal and arealevel socioeconomic inequalities in patients with inflammatory polyarthritis

Author

Harrison, Mark J., Farragher, Tracey M., Clarke, Alexandra M., Manning, Stephanie C., Bunn, Diane K., and Symmons, Deborah P. M.

Abstract

ObjectiveTo describe the relationship between baseline area and personlevel social inequalities and functional disability at 3 years in patients with early inflammatory polyarthritis IP.MethodsA total of 1,393 patients with newonset IP were recruited and allocated an Index of Multiple Deprivation IMD 2004 score based on their area of residence, and a social class based on baseline selfreported occupation. Differences in the Health Assessment Questionnaire HAQ score at baseline and 3 years by IMD or social class were tested. The mean 3year change in HAQ score was compared by IMD and social class, and interactions between these measures examined.ResultsPatients from more deprived areas had poorer 3year HAQ outcome than those from less deprived areas P 0.019, adjusted for baseline HAQ score, age, sex, and symptom duration. The mean difference in HAQ change was most notable between the most deprived IMD4 and least deprived areas IMD1 0.22; 95 confidence interval 95 CI 0.11, 0.34. There was also a significant difference in HAQ score change between patients of the highest SCI and II and lowest social class SCIV and V 0.11; 95 CI 0.02, 0.20. For the mean 95 CI 3year change in HAQ score, a significant interaction exists between IMD score and social class and their association with HAQ scores P 0.001 to modify outcome: IMD1SC I and II −0.23 95 CI −0.40, −0.06 versus IMD 4SC IV and V 0.15 95 CI −0.05, 0.34.ConclusionPerson and arealevel inequalities combine to modify outcome for rheumatoid arthritis. A persons social circumstance and residential environment have independent effects on outcome and are not just alternative measures of the same exposure.

Published
2009
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