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9 results on '"Burel, Emilie"'

4. SARS-CoV-2 quasi-species analysis from patients with persistent nasopharyngeal shedding: potential tool to finest genomic watch

Author

DUDOUET, Pierre, primary, COLSON, Philippe, additional, AHERFI, Sarah, additional, LEVASSEUR, Anthony, additional, BEYE, Mamadou, additional, DELERCE, Jeremy, additional, BUREL, Emilie, additional, LAVRARD, Philippe, additional, BADER, Wahiba, additional, LAGIER, Jean-Christophe, additional, FOURNIER, Pierre-Edouard, additional, SCOLA, Bernard LA, additional, and RAOULT, Didier, additional

Published
2022
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6. Analysis of SARS-CoV-2 Variants From 24,181 Patients Exemplifies the Role of Globalization and Zoonosis in Pandemics

Author

Colson, Philippe, Fournier, Pierre-Edouard, Chaudet, Hervé, Delerce, Jérémy, Giraud-Gatineau, Audrey, Houhamdi, Linda, Andrieu, Claudia, Brechard, Ludivine, Bedotto, Marielle, Prudent, Elsa, Gazin, Céline, Beye, Mamadou, Burel, Emilie, Dudouet, Pierre, Tissot-Dupont, Hervé, Gautret, Philippe, Lagier, Jean-Christophe, Million, Matthieu, Brouqui, Philippe, Parola, Philippe, Fenollar, Florence, Drancourt, Michel, La Scola, Bernard, Levasseur, Anthony, Raoult, Didier, Microbes évolution phylogénie et infections (MEPHI), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut Hospitalier Universitaire Méditerranée Infection (IHU Marseille), Vecteurs - Infections tropicales et méditerranéennes (VITROME), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), and ANR-10-IAHU-0003,Méditerranée Infection,I.H.U. Méditerranée Infection(2010)

Subjects
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, SARS-CoV-2, viruses, zoonosis, pandemics, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, epidemics, variant, classification, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology, mutant, travel
Abstract

International audience; After the end of the first epidemic episode of SARS-CoV-2 infections, as cases began to rise again during the summer of 2020, we at IHU Méditerranée Infection in Marseille, France, intensified the genomic surveillance of SARS-CoV-2, and described the first viral variants. In this study, we compared the incidence curves of SARS-CoV-2-associated deaths in different countries and reported the classification of SARS-CoV-2 variants detected in our institute, as well as the kinetics and sources of the infections. We used mortality collected from a COVID-19 data repository for 221 countries. Viral variants were defined based on ≥5 hallmark mutations along the whole genome shared by ≥30 genomes. SARS-CoV-2 genotype was determined for 24,181 patients using next-generation genome and gene sequencing (in 47 and 11% of cases, respectively) or variant-specific qPCR (in 42% of cases). Sixteen variants were identified by analyzing viral genomes from 9,788 SARS-CoV-2-diagnosed patients. Our data show that since the first SARS-CoV-2 epidemic episode in Marseille, importation through travel from abroad was documented for seven of the new variants. In addition, for the B.1.160 variant of Pangolin classification (a.k.a. Marseille-4), we suspect transmission from farm minks. In conclusion, we observed that the successive epidemic peaks of SARS-CoV-2 infections are not linked to rebounds of viral genotypes that are already present but to newly introduced variants. We thus suggest that border control is the best mean of combating this type of introduction, and that intensive control of mink farms is also necessary to prevent the emergence of new variants generated in this animal reservoir.

Published
2022

7. Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harbouring both substitutions N501Y and E484K in the spike protein

Author

Colson, Philippe, primary, Delerce, Jérémy, additional, Burel, Emilie, additional, Dahan, Jordan, additional, Jouffret, Agnès, additional, Fenollar, Florence, additional, Yahi, Nouara, additional, Fantini, Jacques, additional, La Scola, Bernard, additional, and Raoult, Didier, additional

Published
2021
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9. Analysis of SARS-CoV-2 variants from 24,181 patients exemplifies the role of globalisation and zoonosis in pandemics

Author

Colson, Philippe, primary, Fournier, Pierre-Edouard, additional, Chaudet, Hervé, additional, Delerce, Jérémy, additional, Giraud-Gatineau, Audrey, additional, Houhamdi, Linda, additional, Andrieu, Claudia, additional, Brechard, Ludivine, additional, Bedotto, Marielle, additional, Prudent, Elsa, additional, Gazin, Céline, additional, Beye, Mamadou, additional, Burel, Emilie, additional, Dudouet, Pierre, additional, Tissot-Dupont, Hervé, additional, Gautret, Philippe, additional, Lagier, Jean-Christophe, additional, Million, Matthieu, additional, Brouqui, Philippe, additional, Parola, Philippe, additional, Drancourt, Michel, additional, Scola, Bernard La, additional, Levasseur, Anthony, additional, and Raoult, Didier, additional

Published
2021
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