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1. Aktualizace Doporučení ESC pro diagnostiku a léčbu akutního a chronického srdečního selhání 2021. Vypracovaná Pracovní skupinou pro diagnostiku a léčbu akutního a chronického srdečního selhání Evropské kardiologické společnosti (ESC). Se zvláštním přispěním Evropské asociace srdečního selhání ESC.

Author

TA, McDonagh, primary, Metra, M, additional, Adamo, M, additional, RS, Gardner, additional, Baumbach, A, additional, Böhm, M, additional, Burri, H, additional, Butler, J, additional, Čelutkienė, J, additional, Chioncel, O, additional, JGF, Cleland, additional, MG, Crespo-Leiro, additional, Farmakis, D, additional, Gilard, M, additional, Heymans, S, additional, AW, Hoes, additional, Jaarsma, T, additional, EA, Jankowska, additional, Lainscak, M, additional, CSP, Lam, additional, AR, Lyon, additional, JJV, McMurray, additional, Mebazaa, A, additional, Mindham, R, additional, Muneretto, C, additional, MF, Piepoli, additional, Price, S, additional, GMC, Rosano, additional, Ruschitzka, F, additional, AK, Skibelund, additional, TA, McDonagh, additional, Krejčí, Jan, additional, Špinarová, Lenka, additional, Pařenica, Jiří, additional, Chaloupka, Anna, additional, and Veselý, Jiří, additional

Published
2024
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2. 2023 ESC Guidelines for the management of endocarditis

Author

Delgado, V, Ajmone Marsan, N, de Waha, S, Bonaros, N, Brida, M, Burri, H, Caselli, S, Doenst, T, Ederhy, S, Erba, P, Foldager, D, Fosbøl, E, Kovac, J, Mestres, C, Miller, O, Miro, J, Pazdernik, M, Pizzi, M, Quintana, E, Rasmussen, T, Ristić, A, Rodés-Cabau, J, Sionis, A, Zühlke, L, Borger, M, Delgado, Victoria, Ajmone Marsan, Nina, de Waha, Suzanne, Bonaros, Nikolaos, Brida, Margarita, Burri, Haran, Caselli, Stefano, Doenst, Torsten, Ederhy, Stephane, Erba, Paola Anna, Foldager, Dan, Fosbøl, Emil L, Kovac, Jan, Mestres, Carlos A, Miller, Owen I, Miro, Jose M, Pazdernik, Michal, Pizzi, Maria Nazarena, Quintana, Eduard, Rasmussen, Trine Bernholdt, Ristić, Arsen D, Rodés-Cabau, Josep, Sionis, Alessandro, Zühlke, Liesl Joanna, Borger, Michael A, Delgado, V, Ajmone Marsan, N, de Waha, S, Bonaros, N, Brida, M, Burri, H, Caselli, S, Doenst, T, Ederhy, S, Erba, P, Foldager, D, Fosbøl, E, Kovac, J, Mestres, C, Miller, O, Miro, J, Pazdernik, M, Pizzi, M, Quintana, E, Rasmussen, T, Ristić, A, Rodés-Cabau, J, Sionis, A, Zühlke, L, Borger, M, Delgado, Victoria, Ajmone Marsan, Nina, de Waha, Suzanne, Bonaros, Nikolaos, Brida, Margarita, Burri, Haran, Caselli, Stefano, Doenst, Torsten, Ederhy, Stephane, Erba, Paola Anna, Foldager, Dan, Fosbøl, Emil L, Kovac, Jan, Mestres, Carlos A, Miller, Owen I, Miro, Jose M, Pazdernik, Michal, Pizzi, Maria Nazarena, Quintana, Eduard, Rasmussen, Trine Bernholdt, Ristić, Arsen D, Rodés-Cabau, Josep, Sionis, Alessandro, Zühlke, Liesl Joanna, and Borger, Michael A

Published
2023

4. European Heart Rhythm Association (EHRA) international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections-endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Blomstrom-Lundqvist, C, Traykov, V, Erba, P, Burri, H, Nielsen, J, Bongiorni, M, Poole, J, Boriani, G, Costa, R, Deharo, J, Epstein, L, Saghy, L, Snygg-Martin, U, Starck, C, Tascini, C, Strathmore, N, Blomstrom-Lundqvist C., Traykov V., Erba P. A., Burri H., Nielsen J. C., Bongiorni M. G., Poole J., Boriani G., Costa R., Deharo J. -C., Epstein L. M., Saghy L., Snygg-Martin U., Starck C., Tascini C., Strathmore N., Blomstrom-Lundqvist, C, Traykov, V, Erba, P, Burri, H, Nielsen, J, Bongiorni, M, Poole, J, Boriani, G, Costa, R, Deharo, J, Epstein, L, Saghy, L, Snygg-Martin, U, Starck, C, Tascini, C, Strathmore, N, Blomstrom-Lundqvist C., Traykov V., Erba P. A., Burri H., Nielsen J. C., Bongiorni M. G., Poole J., Boriani G., Costa R., Deharo J. -C., Epstein L. M., Saghy L., Snygg-Martin U., Starck C., Tascini C., and Strathmore N.

Abstract

Pacemakers, implantable cardiac defibrillators, and cardiac resynchronization therapy devices are potentially lifesaving treatments for a number of cardiac conditions but are not without risk. Most concerning is the risk of a cardiac implantable electronic device (CIED) infection, which is associated with significant morbidity, increased hospitalizations, reduced survival, and increased health care costs. Recommended preventive strategies such as administration of intravenous antibiotics before implantation are well-recognized. Uncertainties have remained about the role of various preventive, diagnostic, and treatment measures such as skin antiseptics, pocket antibiotic solutions, antibacterial envelopes, prolonged antibiotics post-implantation, and others. When compared with previous guidelines or consensus statements, the present consensus document gives guidance on the use of novel device alternatives, novel oral anticoagulants, antibacterial envelopes, prolonged antibiotics post-implantation, as well as definitions on minimum quality requirements for centres and operators and volumes. The recognition that an international consensus document focused on management of CIED infections is lacking, the dissemination of results from new important randomized trials focusing on prevention of CIED infections, and observed divergences in managing device-related infections as found in an European Heart Rhythm Association worldwide survey, provided a strong incentive for a Novel 2019 International State-of-the-art Consensus document on risk assessment, prevention, diagnosis, and treatment of CIED infections.

Published
2020

5. European Heart Rhythm Association (EHRA) international consensus document on how to prevent, diagnose, and treat cardiac implantable electronic device infections—endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), the Latin American Heart Rhythm Society (LAHRS), International Society for Cardiovascular Infectious Diseases (ISCVID) and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Blomstrom-Lundqvist, C., Traykov, V., Erba, P. A., Burri, H., Nielsen, J. C., Bongiorni, M. G., Poole, J., Boriani, G., Costa, R., Deharo, J. -C., Epstein, L. M., Saghy, L., Snygg-Martin, U., Starck, C., Tascini, C., Strathmore, N., Kalarus, Z., Boveda, S., Dagres, N., Rinaldi, C. A., Biffi, M., Geller, L., Sokal, A., Birgersdotter-Green, U., Lever, N., Tajstra, M., Kutarski, A., Rodriguez, D. A., Hasse, B., Zinkernagel, A., Mangoni, E., Uppsala Universitet [Uppsala], Tokuda Hospital Sofia, University of Pisa - Università di Pisa, University Medical Center Groningen [Groningen] (UMCG), Aarhus University Hospital, Biorobotics Lab (University of Washington), University of Washington [Seattle], Università degli Studi di Modena e Reggio Emilia, Universidade Paulista [São Paulo] (UNIP), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Département de Cardiologie [Hôpital de la Timone - APHM], Hôpital de la Timone [CHU - APHM] (TIMONE)-Assistance Publique - Hôpitaux de Marseille (APHM), Hofstra University [Hempstead], University of Szeged [Szeged], Department of Image Processing and Computer Graphics [Univ Szeged], University of Gothenburg (GU), West German Heart Center, Universität Duisburg-Essen [Essen], University Parthenope of Naples, The Royal Melbourne Hospital, Clinical sciences, Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Universität Duisburg-Essen = University of Duisburg-Essen [Essen], Università degli Studi di Napoli 'Parthenope' = University of Naples (PARTHENOPE), Blomstrom-Lundqvist, C, Traykov, V, Erba, P, Burri, H, Nielsen, J, Bongiorni, M, Poole, J, Boriani, G, Costa, R, Deharo, J, Epstein, L, Saghy, L, Snygg-Martin, U, Starck, C, Tascini, C, Strathmore, N, Kalarus, Z, Boveda, S, Dagres, N, Rinaldi, C, Biffi, M, Geller, L, Sokal, A, Birgersdotter-Green, U, Lever, N, Tajstra, M, Kutarski, A, Rodriguez, D, Hasse, B, Zinkernagel, A, and Mangoni, E

Subjects
Leads, [SDV]Life Sciences [q-bio], medicine.medical_treatment, Extraction, 030204 cardiovascular system & hematology, law.invention, Defibrillator, 0302 clinical medicine, Randomized controlled trial, law, Health care, Cardiac and Cardiovascular Systems, Endocarditi, 03.02. Klinikai orvostan, 030212 general & internal medicine, Antibiotic prophylaxis, Cardiac resynchronization therapy, Device, Pacemaker, Infection, Kardiologi, Re-implantation, Endocarditis, Latin America/epidemiology, Cardiac implantable electronic device, TRANSVENOUS LEAD EXTRACTION, Defibrillators, Implantable/adverse effects, Thoracic Surgery, General Medicine, STAPHYLOCOCCUS-AUREUS BACTEREMIA, F-18-FDG PET/CT, Defibrillators, Implantable, SINGLE-CENTER EXPERIENCE, 3. Good health, Cardiac implantable electronic devices, EHRA consensus document, Implantable cardioverter-defibrillators, Microbiology, Pacemakers, Cardiothoracic surgery, Risk assessment, Cardiology and Cardiovascular Medicine, EHRA Position Paper, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Asia, Consensus, PERMANENT PACEMAKER IMPLANTATION, CARDIOVERTER-DEFIBRILLATOR IMPLANTATION, Infections, Communicable Diseases, Implantable cardioverter-defibrillator, 03 medical and health sciences, LONG-TERM COMPLICATIONS, ANTIBIOTIC-PROPHYLAXIS, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Infections/diagnosis, Physiology (medical), medicine, Humans, Intensive care medicine, SURGICAL-SITE, business.industry, Cardiac Resynchronization Therapy Devices, Latin America, Lead, RISK-FACTORS, Artificial cardiac pacemaker, Surgery, Electronics, Implantable cardioverterdefibrillators, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

Pacemakers, implantable cardiac defibrillators, and cardiac resynchronization therapy devices are potentially life-saving treatments for a number of cardiac conditions, but are not without risk. Most concerning is the risk of a cardiac implantable electronic device (CIED) infection, which is associated with significant morbidity, increased hospitalizations, reduced survival, and increased healthcare costs. Recommended preventive strategies such as administration of intravenous antibiotics before implantation are well recognized. Uncertainties have remained about the role of various preventive, diagnostic, and treatment measures such as skin antiseptics, pocket antibiotic solutions, anti-bacterial envelopes, prolonged antibiotics post-implantation, and others. Guidance on whether to use novel device alternatives expected to be less prone to infections and novel oral anticoagulants is also limited, as are definitions on minimum quality requirements for centres and operators and volumes. Moreover, an international consensus document on management of CIED infections is lacking. The recognition of these issues, the dissemination of results from important randomized trials focusing on prevention of CIED infections, and observed divergences in managing device-related infections as found in an European Heart Rhythm Association worldwide survey, provided a strong incentive for a 2019 International State-of-the-art Consensus document on risk assessment, prevention, diagnosis, and treatment of CIED infections. This article is simultaneously published also in Eur J Cardiothorac Surg. (https://doi.org/10.1093/ejcts/ezz296) and European Heart Journal (https://doi.org/10.1093/eurheartj/ehaa010). Minor differences in style may appear in each publication, but the article is substantially the same in each journal.

Published
2019
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6. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy

Author

Glikson, M., Nielsen, J. C., Kronborg, M. B., Michowitz, Y., Auricchio, A., Barbash, I. M., Barrabes, J. A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A. J. S., Deharo, J. -C., Delgado, V., Diller, G. -P., Israel, C. W., Keren, A., Knops, R. E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Thylen, I., Tolosana, J. M., Leyva, F., Linde, C., Abdelhamid, M., Aboyans, V., Arbelo, E., Asteggiano, R., Baron-Esquivias, G., Bauersachs, J., Biffi, M., Birgersdotter-Green, U., Bongiorni, M. G., Borger, M. A., Celutkiene, J., Cikes, M., Daubert, J. -C., Drossart, I., Ellenbogen, K., Elliott, P. M., Fabritz, L., Falk, V., Fauchier, L., Fernandez-Aviles, F., Foldager, D., Gadler, F., De Vinuesa, P. G. G., Gorenek, B., Guerra, J. M., Hermann Haugaa, K., Hendriks, J., Kahan, T., Katus, H. A., Konradi, A., Koskinas, K. C., Law, H., Lewis, B. S., Linker, N. J., Lochen, M. -L., Lumens, J., Mascherbauer, J., Mullens, W., Nagy, K. V., Prescott, E., Raatikainen, P., Rakisheva, A., Reichlin, T., Ricci, R. P., Shlyakhto, E., Sitges, M., Sousa-Uva, M., Sutton, R., Suwalski, P., Svendsen, J. H., Touyz, R. M., Van Gelder, I. C., Vernooy, K., Waltenberger, J., Whinnett, Z., Witte, K. K., Qoriany, A., Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), and Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)

Subjects
Pacemaker, Artificial, Cardiac pacing, medicine.medical_treatment, [SDV]Life Sciences [q-bio], Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], cardiac resynchronization therapy, heart failure, temporary pacing, law.invention, law, atrial fibrillation, 610 Medicine & health, ComputingMilieux_MISCELLANEOUS, biology, Cardiac Pacing, Artificial, Syncope (genus), Atrial fibrillation, syncope, Cardiology, cardiovascular system, medicine.symptom, guidelines, cardiac pacing, pacemaker, conduction system pacing, pacing indications, alternate site pacing, complications, pacing in TAVI, bradycardia, Cardiology and Cardiovascular Medicine, Bradycardia, medicine.medical_specialty, Cardiac resynchronization therapy, Guidelines, Physiology (medical), Internal medicine, medicine, Humans, Task force, business.industry, Stroke Volume, 1103 Clinical Sciences, medicine.disease, biology.organism_classification, Heart Rhythm, Cardiovascular System & Hematology, Heart failure, Artificial cardiac pacemaker, business, Atrioventricular block
Abstract

These are the clinical practice guidelines of the European Society of Cardiology on cardiac pacing and cardiac resynchronization therapy, from 2021.

Published
2022
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7. Linee guida ESC 2021 per la diagnosi e il trattamento dello scompenso cardiaco acuto e cronico elaborate dalla Task Force per la diagnosi e il trattamento dello scompenso cardiaco acuto e cronico della Società Europea di Cardiologia (ESC) con il contributo straordinario della Heart Failure Association (HFA) dell’ESC = [2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). With the special contribution of the Heart Failure Association (HFA) of the ESC]

Author

Mcdonagh, T.A., Metra, M., Adamo, M., Gardner, R.S., Baumbach, A., Boehm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J.G.F., Coats, A.J.S., Crespo-Leiro, M.G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A.W., Jaarsma, T., Jankowska, E.A., Lainscak, M., Lam, C.S.P., Lyon, A.R., Mcmurray, John, J., V, Mebazaa, A., Mindham, R., Muneretto, C., Piepoli, M.F., Price, S., Rosano, G.M.C., Ruschitzka, F., and Skibelund, A.K.

Subjects
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Published
2022

9. Clinical practice and implementation of guidelines for the prevention, diagnosis and management of cardiac implantable electronic device infections: results of a worldwide survey under the auspices of the European Heart Rhythm Association

Author

Traykov, V, Bongiorni, M, Boriani, G, Burri, H, Costa, R, Dagres, N, Deharo, J, Epstein, L, Erba, P, Snygg-Martin, U, Nielsen, J, Poole, J, Saghy, L, Starck, C, Strathmore, N, Blomstrom-Lundqvist, C, Traykov V., Bongiorni M. G., Boriani G., Burri H., Costa R., Dagres N., Deharo J. -C., Epstein L. M., Erba P. A., Snygg-Martin U., Nielsen J. C., Poole J. E., Saghy L., Starck C., Strathmore N., Blomstrom-Lundqvist C., Traykov, V, Bongiorni, M, Boriani, G, Burri, H, Costa, R, Dagres, N, Deharo, J, Epstein, L, Erba, P, Snygg-Martin, U, Nielsen, J, Poole, J, Saghy, L, Starck, C, Strathmore, N, Blomstrom-Lundqvist, C, Traykov V., Bongiorni M. G., Boriani G., Burri H., Costa R., Dagres N., Deharo J. -C., Epstein L. M., Erba P. A., Snygg-Martin U., Nielsen J. C., Poole J. E., Saghy L., Starck C., Strathmore N., and Blomstrom-Lundqvist C.

Abstract

AIMS: Cardiac implantable electronic device (CIED) infection rates are increasing. Worldwide compliance and disparities to published guidelines for the prevention, diagnosis and management of these conditions are not well elucidated. The purpose of this survey, therefore, was to clarify these issues through an inquiry to arrhythmia-related associations and societies worldwide. METHODS AND RESULTS: A questionnaire comprising 15 questions related to CIED infections was distributed among members of seven arrhythmia societies worldwide. A total of 234 centres in 62 countries reported implantation rates of which 159 (68.0%) performed more than 200 device implantations per year and 14 (6.0%) performed fewer than 50 implantations per year. The reported rates of CIED infections for 2017 were ≤2% in 78.7% of the centres, while the infection rates exceeded 5% in 7.8% of the centres. Preventive measures for CIED infection differed from published recommendations and varied among different regions mainly in terms of pocket irrigation and administering post-operative antimicrobial therapy the use of which was reported by 39.9% and 44% of the respondents, respectively. Antibacterial envelopes were used by 37.7% of the respondents in selected circumstances. In terms of pocket infection management, 62% of the respondents applied complete system removal as an initial step. Diagnostic pocket needle aspiration and pocket surgical debridement were reported by 15.8% and 11.8% of centres, respectively. CONCLUSION: Clinical practices for prevention and management of CIED do not fully comply with current recommendations and demonstrate considerable regional disparities. Further education and programmes for improved implementation of guidelines are mandatory.

Published
2019

10. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)

Author

Glikson, M., Nielsen, J.C., Kronborg, M.B., Michowitz, Y., Auricchio, A., Barbash, I.M., Barrabes, J.A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A.J.S., Deharo, J.C., Delgado, V., Diller, G.P., Israel, C.W., Keren, A., Knops, R.E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Thylen, I., Tolosana, J.M., European Soc Cardiology ESC, European Heart Rhythm Assoc EHRA, and ESC Sci Document Grp

Subjects
complications, cardiac pacing, alternate site pacing, cardiac resynchronization therapy, heart failure, Guidelines, bradycardia, pacemaker, temporary pacing, pacing indications, syncope, conduction system pacing, atrial fibrillation, pacing in TAVI
Published
2021

12. Outcomes of novel pacing technologies with right ventricular pacing as a primary strategy for patient undergoing transvenous permanent pacing regardless of pacing indication

Author

Abdin, A, primary, Aktaa, S, additional, Vukadinovic, D, additional, Arbelo, E, additional, Boehm, M, additional, Burri, H, additional, Glikson, M, additional, Meyer, C, additional, Munyombwe, T, additional, Nielsen, N C, additional, Vernooy, K, additional, Ukena, C, additional, and Gale, C P, additional

Published
2021
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13. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy

Author

Glikson, M., Nielsen, J.C., Kronborg, M.B., Michowitz, Y., Auricchio, A., Barbash, I.M., Barrabés, J.A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A.J.S., Deharo, J.C., Delgado, V., Diller, G.P., Israel, C.W., Keren, A., Knops, R.E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Vernooy, K., Thylén, I., Tolosana, J.M., Glikson, M., Nielsen, J.C., Kronborg, M.B., Michowitz, Y., Auricchio, A., Barbash, I.M., Barrabés, J.A., Boriani, G., Braunschweig, F., Brignole, M., Burri, H., Coats, A.J.S., Deharo, J.C., Delgado, V., Diller, G.P., Israel, C.W., Keren, A., Knops, R.E., Kotecha, D., Leclercq, C., Merkely, B., Starck, C., Vernooy, K., Thylén, I., and Tolosana, J.M.

Abstract

Contains fulltext : 239015.pdf (Publisher’s version ) (Closed access)

Published
2021

14. EHRA expert consensus statement and practical guide on optimal implantation technique for conventional pacemakers and implantable cardioverter-defibrillators: endorsed by the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), and the Latin-American Heart Rhythm Society (LAHRS)

Author

Burri, H., Starck, C., Auricchio, A., Biffi, M., Burri, M., D'Avila, A., Deharo, J.C., Glikson, M., Israel, C., Lau, C.P., Leclercq, C., Love, C.J., Nielsen, J.C., Vernooy, K., Dagres, N., Boveda, S., Butter, C., Marijon, E., Braunschweig, F., Mairesse, G.H., Gleva, M., Defaye, P., Zanon, F., Lopez-Cabanillas, N., Guerra, J.M., Vassilikos, V.P., Martins Oliveira, M., Burri, H., Starck, C., Auricchio, A., Biffi, M., Burri, M., D'Avila, A., Deharo, J.C., Glikson, M., Israel, C., Lau, C.P., Leclercq, C., Love, C.J., Nielsen, J.C., Vernooy, K., Dagres, N., Boveda, S., Butter, C., Marijon, E., Braunschweig, F., Mairesse, G.H., Gleva, M., Defaye, P., Zanon, F., Lopez-Cabanillas, N., Guerra, J.M., Vassilikos, V.P., and Martins Oliveira, M.

Abstract

Contains fulltext : 238765.pdf (Publisher’s version ) (Closed access), With the global increase in device implantations, there is a growing need to train physicians to implant pacemakers and implantable cardioverter-defibrillators. Although there are international recommendations for device indications and programming, there is no consensus to date regarding implantation technique. This document is founded on a systematic literature search and review, and on consensus from an international task force. It aims to fill the gap by setting standards for device implantation.

Published
2021

17. Poster display I clinical general

Author

Gurgenyan, S. V. Svetlana, Vatinyan, S. K. H., Nicogosyan, K. G., Edilyan, L. B., Chobanyan, B. G., Graf, S., Beheshti, M., Kienast, O., Oezer, S., Angelberger, P., Dudczak, R., Li, S. Shuren, Azevedo, J. C. Jader, Félix, R. C., Corrêa, P. L., Barbirato, G. B., Mesquita, E. T., Volschan, A., Dohmann, H. F., Mesquita, C. T., Peix, A. Amalia, Hidalgo, J., Dorticos, E., Llerena, L., Paredes, A., Macias, C., Valle, L. Del, Cortinas, L., Torres, M., Ponce, F., Petersen, C. L. Claus Leth, Appel, J., Kjaer, A., Awadalla, H. Hany, Hamed, R., Jamal, M., Rayan, M., Mahmoodi, A., Awaad, O., Demerdash, S. El, Adel, A., Kader, M. Abdel, Sarda-Mantel, L. Laure, Michel, J. B., Rouzet, F., Martet, G., Louedec, L., Raguin, O., Vrigneaud, J. M., Saumon, G., Khaw, B. A., Guludec, D. Le, Delahaye, N. Nicolas, Dinanian, S., Slama, M. S., Sarda, L., Tamas, C., Samuel, D., Adams, D., Syrota, A., Moralidis, E. Efstratios, Spyridonidis, T., Arsos, G., Karatzas, N., Karakatsanis, K., Koutelou, M. Maria, Theodorakos, A., Kollaros, N., Manginas, A., Graphakos, S., Tsapaki, V., Kouzoumi, A., Cokkinos, D., Goussetis, E., Prassopoulos, V. Vassilios, Parthenakis, F., Patrianakos, A., Velidaki, A., Koukouraki, S., Papadimitriou, E., Diakakis, G., Maurakis, H., Karakavitsas, N., Vardas, P., Koszegi, Z. Zsolt, Jenei, C., Varga, J., Galuska, L., Edes, I., Ray, Soumendranath, Kundu Bijon, Sarma S K., Day N R., Skouse, D. Douglas, Florimonte, L., Maffioli, L., Piatti, L., Calegari, M., Mancini, R., Bossi, M., Carboni, G. P. Gian Piero, Toriyama, T., Takase, H. Hiroyuki, Okado, T, Tanaka, S., Dohi, Y., Yasuhi, W. Watanabe, Akihiro, S., Akio, Y., Yasunori, W., Kimio, T., Nariaki, E., Yasuhiko, T., Ryo, K., Kasama, S. Shu, Honjo, T., Ichikawa, S., Toyama, T., Kurabayashi, M., Furuhashi, T. Tatsuhiko, Moroi, M., Kunimasa, T., Fukuda, H., Sugi, K., Takeishi, Y. Yasuchika, Arimoto, T., Kubota, I., Kambara, N. Naoshige, Hosokawa, R., Ohba, M., Saito, K., Motomura, H., Kanoi, T., Kume, N., Saji, H., Kita, T., Nohara, R., Akashi, Y. J. Yoshihiro, Musha, H., Kida, K., Suzuki, K., Inoue, K., Kawasaki, K., Hashimoto, N., Miyake, F., Yokoyama, Y. Yasuhiro, Sato, A., Nozato, T., Takahashi, A., Isobe, M., Aonuma, K., Hiroe, M., Peovska, I. Irena, Bosevski, M., Pavlovic, J.Maksimovic, Vavlukis, M., Vallejo, E. Enrique, Rodriguez, G., Jimenez, L., Hernandez, S., Bialostozky, D., Orea, A. Arturo, Asensio, E., Castillo, L., Dorantes, J., Narvaez, R., Gonzalez, O., Zee, P. M. Marc Van der, Verberne, H. J., Straalen, J. P. Van, Fischer, J. C., Sanders, G. T. B., Eck-Smit, B. L. F. Van, Winter, R. J. De, Kostkiewicz, M. Magdalena, Szot, W., Mura, A., Lesniak-Sobelga, A., Olszowska, M., Tracz, W., Ferreira, M. J. Maria Joao, Ferrer-Antunes, A. I., Rodrigues, V., Santos, F., Lima, J., Cerqueira, M. D., Providencia, L. A., Rodrigues, V., Martins, E., Vasconcelos, M. Mariana, Faria, T., Oliveira, A., Garcia, M., Pereira, J., Rocha-Goncalves, F., Lourenço, C. Cândida, Ferrer-Antunes, A., Vieira, H., Martins, R., Franco, F., Providência, L. A., Flotats, A. Albert, Estorch, M., Estorch, M. Montserrat, Mena, E., Camacho, V., Fuertes, J., Rodriguez, A., Flotats, A., Hernandez, M. A., Kulisewsky, J., Carrio, I., Jose-Galcera, J., Caballero-Martínez, A., Jara-Perez, P., Villegas-Garcia, M., Iñigo-García, L., Rosa, J. A. Nuño de la, Florenciano-Sánchez, R., Castillo-Soria, J. F., Valentí-Aldeguer, J. A., Pico-Aracil, F., Martínez-Caballero, A., Villegas-García, M., Castillo-Soria, F., Sánchez-Villanueva, J. G., Rosa, J. A. Nuço de la, Içigo-García, L., Palop, R., Florenciano-Sanchez, R., Lopez-Martínez, I., Jara-Pñrez, P., Rosa, J. A. Nuno de la, Castillo-Soria, F. J., Jara-Pérez, P., Contreras, J., Villegas-Sánchez, M., Obrador, D., Puig, M., Serra-Grima, R., Santaló, M., Carrió, I., Sorensen, J. Jens, Frostfeldt, G., Lindahl, B., Valind, S., Wallentin, L., Somsen, G. A. Aernout, Burri, H., Zaza, S., Fleury, E., Righetti, A., Entok, E. Emre, Birdane, A., Cavusoglu, Y., Ak, I., Timuralp, B., Haworth, M. J., Mitchell, A. R. J. Andrew, Gardner, M. A., Ormerod, O. J. M., Clements, I. P. Ian, Mullan, B. P., MacGregor, C. G., Breen, J. F., Akinboboye, O. O., Nichols, K. J., Wang, Y., Dim, U. Uzodinma, Lachman, J., Nichols, K. J., Muratore, K. A., Aracely, N., Haag, E. S., Druz, R. S. Regina, Gopal, A. S., Borges, A., Ngai, K. C., Dim, U. R., Wiley, M., Freeman, J., Kitchen, S., Graham, D., Schindel, M., Clark, E., Speiser, D., Hackney, T., Feldkamp, M., and Rosamond, T. Thomas

Published
2005
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18. ESC Core Curriculum for the General Cardiologist (2013)

Author

Gillebert, Thierry C., Brooks, Nicholas, Fontes-Carvalho, Ricardo, Fras, Zlatko, Gueret, Pascal, Lopez-Sendon, Jose, Salvador, Maria Jesus, van den Brink, Renee B. A., Smiseth, Otto A., Griebenow, Reinhard, Kearney, Peter, Vahanian, Alec, Bauersachs, J., Bax, J., Burri, H., Caforio, A.L.P., Calvo, F., Charron, P., Ertl, G., Flachskampf, F., Giannuzzi, P., Gibbs, S., Gonçalves, L., González-Juanatey, J.R., Hall, J., Herpin, D., Iaccarino, G., Iung, B., Kitsiou, A., Lancellotti, P., McDonough, T., Monsuez, J.J., Nuñez, I.J., Plein, S., Porta-Sánchez, A., Priori, S., Price, S., Regitz-Zagrosek, V., Reiner, Z., Ruilope, L.M., Schmid, J.P., Sirnes, P. A., Sousa-Ouva, M., Stępińska, J., Szymanski, C., Taggart, D., Tendera, M., Tokgözog[Combining Caron]lu, L., Trindade, P., Zeppenfeld, K., Joubert, L., and Carrera, C.

Published
2013
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19. Low T/R ratio in inferolateral leads: A new ECG marker of sudden cardiac arrest in patients with a spontaneous type 1 Brugada pattern

Author

Delinière, A., primary, Baranchuk, A., additional, Bessiere, F., additional, Defaye, P., additional, Marijon, E., additional, Le Vavasseur, O., additional, Dobreanu, D., additional, Scridon, A., additional, Da Costa, A., additional, Delacrétaz, E., additional, Kouakam, C., additional, Eschalier, R., additional, Extramiana, F., additional, Leenhardt, A., additional, Burri, H., additional, Winum, P.F., additional, Taieb, J., additional, Bouet, J., additional, Rosianu, H., additional, and Chevalier, P., additional

Published
2020
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23. EHRA White Paper: knowledge gaps in arrhythmia management-status 2019

Author

Goette, A., Auricchio, A., Boriani, G., Braunschweig, F., Terradellas, J.B., Burri, H., Camm, A.J., Crijns, H., Dagres, N., Deharo, J.C., Dobrev, D., Hatala, R., Hindricks, G., Hohnloser, S.H., Leclercq, C., Lewalter, T., Lip, G.Y.H., Merino, J.L., Mont, L., Prinzen, F., Proclemer, A., Purerfellner, H., Savelieva, I., Schilling, R., Steffel, J., Gelder, I.C. van, Zeppenfeld, K., Zupan, I., Heidbuchel, H., Boveda, S., Defaye, P., Brignole, M., Chun, J., Ramos, J.M.G., Fauchier, L., Svendsen, J.H., Traykov, V.B., Heinzel, F.R., ESC Sci Document Grp, Otto-von-Guericke-Universität Magdeburg, Center for Computational Medicine in Cardiology [Lugano], Università della Svizzera italiana = University of Italian Switzerland (USI), Università degli Studi di Modena e Reggio Emilia, University of Geneva [Switzerland], Hôpital de la Timone [CHU - APHM] (TIMONE), Goethe-University Frankfurt am Main, Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Cardiology Department, Thorax Clinic Institute, Hospital Cliınic, Institut d'Investigacions Biomèdiques [Barcelona], Universitat de Barcelona (UB), Department of Physiology [Maastricht], Maastricht University [Maastricht], Universiteit Antwerpen [Antwerpen], RS: CARIM - R2.01 - Clinical atrial fibrillation, Cardiologie, MUMC+: MA Cardiologie (9), RS: Carim - H01 Clinical atrial fibrillation, Fysiologie, RS: CARIM - R2 - Cardiac function and failure, RS: Carim - H06 Electro mechanics, Clinical sciences, Otto-von-Guericke-Universität Magdeburg = Otto-von-Guericke University [Magdeburg] (OVGU), Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), Université de Genève = University of Geneva (UNIGE), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Universiteit Antwerpen = University of Antwerpen [Antwerpen], Cardiovascular Centre (CVC), and ESC Sci Document Grp

Subjects
Biomedical Research, IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR, medicine.medical_treatment, Medizin, Management of atrial fibrillation, RHYTHM SOCIETY HRS, White Paper, Heart failure, 030204 cardiovascular system & hematology, Sudden death, 03 medical and health sciences, 0302 clinical medicine, White paper, Ventricular tachycardia ablation, AIAC ITALIAN ASSOCIATION, Physiology (medical), PERSISTENT ATRIAL-FIBRILLATION, Tachycardia, medicine, Humans, Organizational Objectives, 030212 general & internal medicine, PULMONARY VEIN ISOLATION, Societies, Medical, EXPERT CONSENSUS STATEMENT, European Heart Rhythm Association, CATHETER ABLATION, ddc:616, Medical education, CARDIAC-RESYNCHRONIZATION THERAPY, VENTRICULAR-TACHYCARDIA ABLATION, business.industry, Arrhythmia, Fibrillation, Cardiac arrhythmia, Arrhythmias, Cardiac, Subject (documents), Implantable cardioverter-defibrillator, ATRIOVENTRICULAR NODE ABLATION, 3. Good health, Heart Rhythm, Europe, Arrhythmias, Cardiac/therapy, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Human medicine, business, Cardiology and Cardiovascular Medicine
Abstract

Clinicians accept that there are many unknowns when we make diagnostic and therapeutic decisions. Acceptance of uncertainty is essential for the pursuit of the profession: bedside decisions must often be made on the basis of incomplete evidence. Over the years, physicians sometimes even do not realize anymore which the fundamental gaps in our knowledge are. As clinical scientists, however, we have to halt and consider what we do not know yet, and how we can move forward addressing those unknowns. The European Heart Rhythm Association (EHRA) believes that scanning the field of arrhythmia / cardiac electrophysiology to identify knowledge gaps which are not yet the subject of organized research, should be undertaken on a regular basis. Such a review (White Paper) should concentrate on research which is feasible, realistic, and clinically relevant, and should not deal with futuristic aspirations. It fits with the EHRA mission that these White Papers should be shared on a global basis in order to foster collaborative and needed research which will ultimately lead to better care for our patients. The present EHRA White Paper summarizes knowledge gaps in the management of atrial fibrillation, ventricular tachycardia/sudden death and heart failure.

Published
2019
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31. Risk stratification of cardiovascular and heart failure hospitalizations using integrated device diagnostics in patients with a cardiac resynchronization therapy defibrillator

Author

Burri H, da Costa A, Quesada A, Ricci R, Favale S, Clementy N, Boscolo G, Segura Villalobos F, Stefano L, Sharma V, Boriani G, and MORE-CARE Investigators

Subjects
virus diseases
Abstract

Aims Cardiac resynchronization therapy defibrillators (CRT-D) are able to monitor various parameters that may be combined by an automatic algorithm to provide a heart failure risk status (HFRS). We sought to validate the HFRS for stratifying patient risk, evaluate its association with heart failure (HF) symptoms, and investigate its utility for triage of automatic alerts. Methods and results Data from 722 patients included in the MORE-CARE trial were analysed in a post hoc analysis. A high HFRS was associated with a significantly increased risk of admission over the next 30 days with a relative risk for cardiovascular hospitalization (CVH) of 4.5 (95% CI: 3.1-6.6, P < 0.001), of HF hospitalization of 6.3 (95% CI: 3.9-10.2, P < 0.001) and of non-HF related CVH of 3.5 (95% CI: 2.0-6.9, P < 0.001). The negative predictive value of low or medium HFRS for these admissions was >= 98%. A high HFRS was associated with an increased risk of HF symptoms. Of all the automatic remote monitoring alerts generated during the study, only 10% had a high HFRS. Conclusion The HFRS is able to risk-stratify CRT-D patients, which is potentially useful for managing automatic remote monitoring alerts, by focusing attention on the minority of high-risk patients.

Published
2018

32. Prognostic significance of a low T/R ratio in Brugada Syndrome

Author

Delinière, A., primary, Baranchuk, A., additional, Bessiere, F., additional, Defaye, P., additional, Marijon, E., additional, Le Vavasseur, O., additional, Dobreanu, D., additional, Scridon, A., additional, Da Costa, A., additional, Delacrétaz, E., additional, Kouakam, C., additional, Eschalier, R., additional, Burri, H., additional, Winum, P.F., additional, Taieb, J., additional, Bouet, J., additional, Rosianu, H., additional, and Chevalier, P., additional

Published
2019
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33. P3817Diagnostic yield of genetic testing in cardiac arrest survivors with or without clinical evidence of cardiac disease: A swiss experience

Author

Asatryan, B, primary, Seiler, J, additional, Servatius, H, additional, Noti, F, additional, Tanner, H, additional, Roten, L, additional, Dillier, R, additional, Saguner, A M, additional, Mueller, S A, additional, Duru, F, additional, Auricchio, A, additional, Ammann, P, additional, Reichlin, T, additional, Burri, H, additional, and Medeiros-Domingo, A, additional

Published
2018
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34. 2114Impact of contact force sensing technology on catheter ablation success of idiopathic premature ventricular contractions originating from the outflow tracts

Author

Reichlin, T, primary, Baldinger, S, additional, Seiler, J, additional, Pruvot, E, additional, Bisch, L, additional, Ammann, P, additional, Berte, B, additional, Haegeli, L, additional, Mueller, A, additional, Namdar, M, additional, Burri, H, additional, Auricchio, A, additional, Knecht, S, additional, Kuehne, M, additional, and Sticherling, C, additional

Published
2018
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35. P3816New electrocardiographic risk score for the prediction of ventricular fibrillation in Brugada type 1 ECG pattern

Author

Deliniere, A, primary, Baranchuk, A, additional, Giai, J, additional, Maucort-Boulch, D, additional, Defaye, P, additional, Marijon, E, additional, Le Vavasseur, O, additional, Dobreanu, D, additional, Dacosta, A, additional, Delacretaz, E, additional, Kouakam, C, additional, Eschalier, R, additional, Burri, H, additional, Winum, P, additional, and Chevalier, P, additional

Published
2018
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38. Anaesthesiemethoden

Author

Feurstein, V., Niederer, W., Hügin, W., Mayrhofer, O., Benad, G., Kern, F., Henschel, W. F., Kreuscher, H., Droh, R., Frey, R., Nolte, H., Oehmig, H., Chott, F., Bergmann, H., Baum, M., Zindler, M., Dudziak, R., Pulver, K. G., Kucher, R., Eisterer, H., Vogel, W., Holländer, L. P., Burri, H. P., Halmágyi, M., Lehmann, Ch., Frey, R., editor, Hügin, W., editor, and Mayrhofer, O., editor

Published
1972
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45. ESC core curriculum for the general cardiologist (2013)

Author

European Society of Cardiology, Committee for Education, Authors/Task Force Members, Gillebert, Tc, Brooks, N, Fontes-Carvalho, R, Fras, Z, Gueret, P, Lopez-Sendon, J, Salvador, Mj, van den Brink RB, Smiseth, Oa, Observer on behalf of the UEMS (Cardiology Section), Griebenow, R, Review, Coordinators, Kearney, P, Vahanian, A, Contributors and reviewers, Bauersachs, J, Bax, J, Burri, H, Caforio, A, Calvo, F, Charron, P, Ertl, G, Flachskampf, F, Giannuzzi, P, Gibbs, S, Gonçalves, L, González-Juanatey, Jr, Hall, J, Herpin, D, Iaccarino, G, Iung, B, Kitsiou, A, Lancellotti, P, Mcdonough, T, Monsuez, Jj, Nuñez, Ij, Plein, S, Porta-Sánchez, A, Priori, S, Price, S, Regitz-Zagrosek, V, Reiner, Z, Ruilope, Lm, Schmid, Jp, Sirnes, Pa, Sousa-Ouva, M, Stepinska, J, Szymanski, C, Taggart, D, Tendera, M, Tokgözoglu, L, Trindade, P, Zeppenfeld, K, Esc, Staff, Joubert, L, Carrera, C., Gillebert, T. C., Brooks, N., Fontes-Carvalho, R., Fras, Z., Gueret, P., Lopez-Sendon, J., Salvador, M. J., Van Den Brink, R. B. A., Smiseth, O. A., Griebenow, R., Kearney, P., Vahanian, A., Bauersachs, J., Bax, J., Burri, H., Caforio, A. L. P., Calvo, F., Charron, P., Ertl, G., Flachskampf, F., Giannuzzi, P., Gibbs, S., Goncalves, L., Gonzalez-Juanatey, J. R., Hall, J., Herpin, D., Iaccarino, G., Iung, B., Kitsiou, A., Lancellotti, P., Mcdonough, T., Monsuez, J. J., Nunez, I. J., Plein, S., Porta-Sanchez, A., Priori, S., Price, S., Regitz-Zagrosek, V., Reiner, Z., Ruilope, L. M., Schmid, J. P., Sirnes, P. A., Sousa-Ouva, M., Stepinska, J., Szymanski, C., Taggart, D., Tendera, M., Tokgozoglu, L., Trindade, P., Zeppenfeld, K., Joubert, L., and Carrera, C.

Subjects
health care facilities, manpower, and services, Teaching method, Behaviours, Certification, Sports Medicine, GUIDELINES, RECOMMENDATIONS, Electrocardiography, Pregnancy, Competence, CME, Medicine and Health Sciences, Heart Team, Medical History Taking, health care economics and organizations, Schools, Medical, Societies, Medical, Skills, Rehabilitation, VERSION 2009, ASSOCIATION, Objectives, EUROPEAN-SOCIETY, Europe, Obstetrics, Knowledge, CARDIOVASCULAR-DISEASE, Pharmacology, Clinical, Cardiology, HEART-FAILURE, Female, Clinical Competence, Curriculum, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Attitude of Health Personnel, Genetics, Medical, education, Heart Centre, Specialty, MEDLINE, Expertise, DIAGNOSIS, Core curriculum, Education, health services administration, Internal medicine, medicine, Internal Medicine, MANAGEMENT, Humans, Training, cardiovascular diseases, Competence (human resources), Physical Examination, Preventive healthcare, business.industry, Teaching, Subspecialties, Cardiopulmonary Resuscitation, Cardiac Imaging Techniques, Education, Medical, Graduate, Attitudes, Preventive Medicine, business, End-terms, TASK-FORCE
Abstract

The previous Core Curriculum for the General Cardiologist defined a model for cardiology training in Europe and it has been adopted as the standard for regulating training, for access to the specialty (certification), and for revalidation in several countries.1 During the last 5 years we have witnessed profound changes in cardiological practice. The work of both hospital and independent cardiologists has been better integrated with that of general practitioners. It has taken into account the requirements of national authorities, re-imbursement organizations, and hospital administrations. Cardiologists face changing patient expectations. General cardiologists, interventional …

Published
2013

46. Towards complete male individualization with rapidly mutating Y-chromosomal STRs

Author

Ballantyne, KN, Ralf, A, Aboukhalid, R, Achakzai, NM, Anjos, MJ, Ayub, Q, Balažic, J, Ballantyne, J, Ballard, DJ, Berger, B, Bobillo, C, Bouabdellah, M, Burri, H, Butler, J, Capal, T, Caratti, S, Carracedo, A, Cartault, F, Carvalho, EF, Cheng, B, Coble, MD, Comas, D, Corach, D, D'Amato, ME, Davison, S, de Carvalho, EF, de Knijff, Peter, de Ungria, M, Decorte, Ronny, Dobosz, T, Dupuy, BM, Elmrghni, S, Gliwinski, M, Gomes, SC, Grol, L, Haas, C, Hanson, E, Henke, J, Hill, CR, Holmlund, G, Honda, K, Immel, U, Inoue, S, Jobling, MA, Kaddura, M, Kim, JS, Kim, SH, Kim, W, King, TE, Klausriegler, E, Kling, D, Kovacevic, LL, Kovatsi, L, Krajewski, P, Kravchenko, S, Larmuseau, Maarten, Lee, EY, Lee, SH, Lessig, R, Livshits, LA, Marjanovic, D, Minarik, M, Mizuno, N, Moreira, H, Morling, N, Mukherjee, M, Nagaraju, J, Neuhuber, F, Nie, S, Nilasitsataporn, P, Nishi, T, Oh, HH, Olofsson, J, Onofri, V, Palo, JU, Pamjav, H, Parson, W, Payet, C, Petlach, M, Phillips, C, Ploski, R, Prasad, SPR, Primorac, D, Purnnomo, GA, Purps, J, Rangel, H, Rebala, K, Rerkamnuaychoke, B, Rey, D, Robino, C, Rodríguez, F, Roewer, L, Rosa, A, Sajantila, A, Sala, A, Salvador, J, Sanz, P, Schmitt, C, Sharma, AK, Silva, DA, Shin, KJ, Sijen, T, Sirker, M, Siváková, D, Skaro, V, Solano-Matamoros, C, Souto, L, Stenzl, V, Sudoyo, H, Syndercombe-Court, D, Tagliabracci, A, Taylor, D, Tillmar, A, Tsybovsky, IS, Tyler-Smith, C, van der Gaag, K, Vanek, D, Völgyi, A, Ward, D, Willemse, P, Winkler, C, Yap, EPH, Yong, RYY, Zupanic Pajnic, I, and Kayser, M

Subjects
haplotypes, paternal lineage, RM YSTRs, Y-STRs, forensic, Y-chromosome
Abstract

Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutating (RM) Y-STRs in 14,644 related and unrelated males from 111 worldwide populations. Strikingly, >99% of the 12,272 unrelated males were completely individualized. Haplotype diversity was extremely high (global: 0.9999985, regional: 0.99836–0.9999988). Haplotype sharing between populations was almost absent except for six (0.05%) of the 12,156 haplotypes. Haplotype sharing within populations was generally rare (0.8% nonunique haplotypes), significantly lower in urban (0.9%) than rural (2.1%) and highest in endogamous groups (14.3%). Analysis of molecular variance revealed 99.98% of variation within populations, 0.018% among populations within groups, and 0.002% among groups. Of the 2,372 newly and 156 previously typed male relative pairs, 29% were differentiated including 27% of the 2,378 father–son pairs. Relative to Yfiler, haplotype diversity was increased in 86% of the populations tested and overall male relative differentiation was raised by 23.5%. Our study demonstrates the value of RMY-STRs in identifying and separating unrelated and related males and provides a reference database. ispartof: Human Mutation vol:35 issue:8 pages:1021-1032 status: published

Published
2014

48. Toward Male Individualization with Rapidly Mutating Y-Chromosomal Short Tandem Repeats

Author

Ballantyne, K.N., Ralf, A., Aboukhalid, R., Achakzai, N.M., Anjos, M.J., Ayub, Q., Balazic, J., Ballantyne, J., Ballard, D.J., Berger, B., Bobillo, C., Bouabdellah, M., Burri, H., Capal, T., Caratti, S., Cardenas, J., Cartault, F., Carvalho, E.F., Carvalho, M., Cheng, B.W., Coble, M.D., Comas, D., Corach, D., D'Amato, M.E., Davison, S., Knijff, P. de, Ungria, M.C.A. de, Decorte, R., Dobosz, T., Dupuy, B.M., Elmrghni, S., Gliwinski, M., Gomes, S.C., Grol, L., Haas, C., Hanson, E., Henke, J., Henke, L., Herrera-Rodriguez, F., Hill, C.R., Holmlund, G., Honda, K., Immel, U.D., Inokuchi, S., Jobling, M.A., Kaddura, M., Kim, J.S., Kim, S.H., Kim, W., King, T.E., Klausriegler, E., Kling, D., Kovacevic, L., Kovatsi, L., Krajewski, P., Kravchenko, S., Larmuseau, M.H.D., Lee, E.Y., Lessig, R., Livshits, L.A., Marjanovic, D., Minarik, M., Mizuno, N., Moreira, H., Morling, N., Mukherjee, M., Munier, P., Nagaraju, J., Neuhuber, F., Nie, S.J., Nilasitsataporn, P., Nishi, T., Oh, H.H., Olofsson, J., Onofri, V., Palo, J.U., Pamjav, H., Parson, W., Petlach, M., Phillips, C., Ploski, R., Prasad, S.P.R., Primorac, D., Purnomo, G.A., Purps, J., Rangel-Villalobos, H., Rebala, K., Rerkamnuaychoke, B., Gonzalez, D.R., Robino, C., Roewer, L., Rosa, A., Sajantila, A., Sala, A., Salvador, J.M., Sanz, P., Schmitt, C., Sharma, A.K., Silva, D.A., Shin, K.J., Sijen, T., Sirker, M., Sivakova, D., Skaro, V., Solano-Matamoros, C., Souto, L., Stenzl, V., Sudoyo, H., Syndercombe-Court, D., Tagliabracci, A., Taylor, D., Tillmar, A., Tsybovsky, I.S., Tyler-Smith, C., Gaag, K.J. van der, Vanek, D., Volgyi, A., Ward, D., Willemse, P., Yap, E.P.H., Yong, R.Y.Y., Pajnic, I.Z., Kayser, M., Hjelt Institute (-2014), Forensic Medicine, PaleOmics Laboratory, and Genetic Identification

Subjects
Male, Rural Population, haplotypes, Y-chromosome, Y-STRs, RM Y-STRs, paternal lineage, forensic, Asia, Forensic Science, Urban Population, Cell- och molekylärbiologi, education, Paternity, Gene Frequency, Humans, Alleles, Chromosomes, Human, Y, 1184 Genetics, developmental biology, physiology, Genetic Variation, DNA Fingerprinting, RM Y-STRs, Y-STRs, Y-chromosome, forensic, haplotypes, paternal lineage, Pedigree, Europe, Genetics, Population, Africa, 3111 Biomedicine, Americas, Cell and Molecular Biology, Microsatellite Repeats, Rättsmedicin
Abstract

Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutating (RM) Y-STRs in 14,644 related and unrelated males from 111 worldwide populations. Strikingly, >99% of the 12,272 unrelated males were completely individualized. Haplotype diversity was extremely high (global: 0.9999985, regional: 0.99836-0.9999988). Haplotype sharing between populations was almost absent except for six (0.05%) of the 12,156 haplotypes. Haplotype sharing within populations was generally rare (0.8% nonunique haplotypes), significantly lower in urban (0.9%) than rural (2.1%) and highest in endogamous groups (14.3%). Analysis of molecular variance revealed 99.98% of variation within populations, 0.018% among populations within groups, and 0.002% among groups. Of the 2,372 newly and 156 previously typed male relative pairs, 29% were differentiated including 27% of the 2,378 father-son pairs. Relative to Yfiler, haplotype diversity was increased in 86% of the populations tested and overall male relative differentiation was raised by 23.5%. Our study demonstrates the value of RMY-STRs in identifying and separating unrelated and related males and provides a reference database. Published 2014 Wiley Periodicals, Inc.**

Published
2014

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