20 results on '"Burton, Louisa-Jane"'
Search Results
2. RECREATE: a study protocol for a multicentre pilot cluster randomised controlled trial (cRCT) in UK stroke services evaluating an intervention to reduce sedentary behaviour in stroke survivors (Get Set Go) with embedded process and economic evaluations
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Airlie, Jennifer, primary, Burton, Louisa-Jane, additional, Copsey, Bethan, additional, English, Coralie, additional, Farrin, Amanda, additional, Fitzsimons, Claire F, additional, Holloway, Ivana, additional, Horrocks, Judith, additional, Johansson, Jessica Faye, additional, Mead, Gillian, additional, Moreau, Lauren A, additional, Ozer, Seline, additional, Patel, Anita, additional, Yaziji, Nahel, additional, and Forster, Anne, additional
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- 2023
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3. An intervention to support stroke survivors and their carers in the longer term (LoTS2Care): study protocol for the process evaluation of a cluster randomised controlled feasibility trial
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Hardicre, Natasha K., Crocker, Thomas F, Wright, Alan, Burton, Louisa-Jane, Ozer, Seline, Atkinson, Ross, House, Allan, Hewison, Jenny, McKevitt, Christopher, Forster, Anne, Farrin, Amanda J., and on behalf of the LoTS2Care Programme Management Group
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- 2018
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4. A systematic review and meta-analysis of non-workplace interventions to reduce time spend in sedentary in adults
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Hall, Jessica Faye, Corepal, Rekesh, Crocker, Thomas F, Lam, Natalie, Burton, Louisa-Jane, Birch, Karen, Carter, Gill, Clarke, David J, English, Coralie, Farrin, Amanda J, Fitzsimons, Claire, Hall, Jennifer, Holloway, Ivana, Ozer, Seline, Lawton, Rebecca, Mead, Gillian, Morton, Sarah, Patel, Anita, and Forster, Anne
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Background Sedentary behaviour has been the focus of considerable clinical, policy and research interest due to its detrimental effects on health and wellbeing. This systematic review aims to (1) develop a more precise description of different categories of interventions that aim to reduce sedentary time in adults by identifying specific components that form an intervention; (2) explore the effect of different categories of interventions in reducing time spent sedentary in adults.Methods Ten electronic databases, websites of relevant organisations (e.g. the Sedentary Behaviour Research Network), and relevant reviews were searched. Inclusion criteria: Randomised controlled trials (RCTs), including cluster and randomised cross-over trials, in the adult population (clinical and non-clinical). Any study including a measure of sedentary behaviour was included even if reducing sedentary behaviour was not the primary aim. Exclusion criteria: Interventions delivered in schools, colleges, or workplaces; studies investigating the immediate effects of breaking up sitting time as part of a supervised (usually laboratory-based) intervention. Two review authors conducted data extraction and quality assessment (GRADE approach).Results Searches identified 39,223 records, of which 85 studies met the inclusion criteria and were included in the review. Interventions shown to significantly reduce time spent sedentary were those which incorporated the provision of information, education, or support (advice/recommendations), in conjunction with either counselling (mean difference: -52.24 minutes/day; 95% CI: -85.37 to -19.10) or a form of structured/prescribed physical activity (standardised mean difference: -0.15; 95% CI: -0.23 to -0.07). However, this positive effect was not maintained at follow-up. No interventions were shown to break up prolonged sitting.Conclusions This review presents a novel way of categorising interventions according to the types of components they comprised. There is evidence that interventions might be effective in reducing time spent sedentary immediately post-intervention. There were limited studies measuring sustained behaviour change.
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- 2021
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5. Service usersʼ views of the assessment process in stroke rehabilitation
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Tyson, Sarah F, Burton, Louisa-Jane, McGovern, Alison, and Sharifi, Sudi
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- 2014
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6. A systematic review and meta-analysis of non-workplace interventions to reduce time spent sedentary in adults
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Hall, Jessica Faye, primary, Corepal, Rekesh, additional, Crocker, Thomas F, additional, Lam, Natalie, additional, Burton, Louisa-Jane, additional, Birch, Karen, additional, Carter, Gill, additional, Clarke, David J, additional, English, Coralie, additional, Farrin, Amanda J, additional, Fitzsimons, Claire, additional, Hall, Jennifer, additional, Holloway, Ivana, additional, Ozer, Seline, additional, Lawton, Rebecca, additional, Mead, Gillian, additional, Morton, Sarah, additional, Patel, Anita, additional, and Forster, Anne, additional
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- 2021
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7. Experiences and views of receiving and delivering information about recovery in acquired neurological conditions: a systematic review of qualitative literature
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Burton, Louisa-Jane, primary, Forster, Anne, additional, Johnson, Judith, additional, Crocker, Thomas F., additional, Tyson, Sarah F., additional, Wray, Faye, additional, and Clarke, David J., additional
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- 2021
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8. Longer-term health and social care strategies for stroke survivors and their carers: the LoTS2Care research programme including cluster feasibility RCT
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Forster, Anne, primary, Ozer, Seline, additional, Crocker, Thomas F, additional, House, Allan, additional, Hewison, Jenny, additional, Roberts, Elaine, additional, Dickerson, Josie, additional, Carter, Gill, additional, Hulme, Claire, additional, Fay, Matthew, additional, Richardson, Gillian, additional, Wright, Alan, additional, McKevitt, Christopher, additional, McEachan, Rosemary, additional, Foy, Robbie, additional, Barnard, Lorna, additional, Moreau, Lauren, additional, Prashar, Arvin, additional, Clarke, David, additional, Hardicre, Natasha, additional, Holloway, Ivana, additional, Brindle, Richard, additional, Hall, Jessica, additional, Burton, Louisa-Jane, additional, Atkinson, Ross, additional, Hawkins, Rebecca J, additional, Brown, Lesley, additional, Cornwall, Nicola, additional, Dawkins, Bryony, additional, Meads, David, additional, Schmitt, Laetitia, additional, Fletcher, Marie, additional, Speed, Michael, additional, Grenfell, Katie, additional, Hartley, Suzanne, additional, Young, John, additional, and Farrin, Amanda, additional
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- 2021
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9. What influences provision of information about recovery on stroke units? A focused ethnographic case study.
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Burton, Louisa-Jane, Forster, Anne, Johnson, Judith, Crocker, Thomas F., Tyson, Sarah F., and Clarke, David J.
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MEDICAL logic , *STROKE units , *ETHNOLOGY , *STROKE patients , *SEMI-structured interviews , *INFORMATION needs - Abstract
Patients and carers frequently report dissatisfaction with post-stroke information provision. This study aimed to develop an in-depth understanding of the factors influencing provision of information about recovery in stroke units. Focused ethnographic case-studies in two UK stroke units, including non-participant observations and semi-structured interviews with professionals, patients and carers, and documentary analysis. A Framework approach to analysis was undertaken. Twenty patients, 17 carers and 47 professionals participated. The unpredictable recovery trajectory led professionals to present prognostic estimates as uncertain possibilities. The need to maintain patients' motivation limited sharing of negative predictions, and generic information over-emphasised the importance of therapy in recovery. A structured multidisciplinary team approach to delivering information improved consistency. Complex clinical reasoning was required to identify and meet patients' needs. Hospital environments and routines restricted opportunities for dialogue, particularly with carers. The process of providing information about post-stroke recovery is complex, requiring enhanced clinical reasoning and communication. The challenges faced by professionals are numerous and if not addressed can result in suboptimal provision. Practice implications: Professionals should develop a co-ordinated multidisciplinary approach to information provision; and engage in dialogue to ensure a tailored approach to identifying and meeting patients' and carers' information needs. • Stroke unit patients and carers report dissatisfaction with recovery information. • Ethnographic methods facilitated in-depth exploration of information provision. • A wide range of factors influence provision of recovery information. • A co-ordinated multidisciplinary approach can facilitate information provision. • Staff training is required to support effective delivery and improve confidence. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
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Clarke, David J, primary, Burton, Louisa-Jane, additional, Tyson, Sarah F, additional, Rodgers, Helen, additional, Drummond, Avril, additional, Palmer, Rebecca, additional, Hoffman, Alex, additional, Prescott, Matthew, additional, Tyrrell, Pippa, additional, Brkic, Lianne, additional, Grenfell, Katie, additional, and Forster, Anne, additional
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- 2018
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11. Staff perceptions of using outcome measures in stroke rehabilitation
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Burton, Louisa-Jane, primary, Tyson, Sarah, additional, and McGovern, Alison, additional
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- 2012
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12. Staff perceptions of using outcome measures in stroke rehabilitation.
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Burton, Louisa-Jane, Tyson, Sarah, and McGovern, Alison
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Purpose: The use of standardised outcome measures is an integral part of stroke rehabilitation and is widely recommended as good practice. However, little is known about how measures are actually used or their impact. This study aimed to identify current clinical practice; how healthcare professionals working in stroke rehabilitation use outcome measures and their perceptions of the benefits and barriers to use. Method: Eighty-four Health Care Professionals and 12 service managers and commissioners working in stroke services across a large UK county were surveyed by postal questionnaire. Results: Ninety-six percent of clinical respondents used at least one measure, however, less than half used measures regularly during a patient's stay. The mean number of tools used was 3.2 (SD = 1.9). Eighty-one different tools were identified; 16 of which were unpublished and unvalidated. Perceived barriers in using outcome measures in day-to-day clinical practice included lack of resources (time and training) and lack of knowledge of appropriate measures. Benefits identified were to demonstrate the effectiveness of rehabilitation interventions and monitor patients' progress. Conclusions: Although the use of outcome measures is prevalent in clinical practice, there is little consistency in the tools utilised. The term 'outcome measures' is used, but staff rarely used the measures at appropriate time points to formally assess and evaluate outcome. The term 'measurement tool' more accurately reflects the purposes to which they were put and potential benefits. Further research to overcome the barriers in using standardised measurement tools and evaluate the impact of implementation on clinical practice is needed. [ABSTRACT FROM AUTHOR]
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- 2013
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13. Service users’ views of the assessment process in stroke rehabilitation.
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Tyson, Sarah F, Burton, Louisa-Jane, McGovern, Alison, and Sharifi, Sudi
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- 2009
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14. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
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Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, Forster, Anne, Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, and Forster, Anne
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Objective: To identify why the National Clinical Guideline recommendation of 45 minutes of each appropriate therapy daily is not met in many English stroke units. Design: Mixed-methods case-study evaluation, including modified process mapping, non-participant observations of service organisation and therapy delivery, documentary analysis and semi-structured interviews. Setting: Eight stroke units in four English regions. Subjects: Seventy-seven patients with stroke, 53 carers and 197 stroke unit staff were observed; 49 patients, 50 carers and 131 staff participants were interviewed. Results: Over 1000 hours of non-participant observations and 433 patient-specific therapy observations were undertaken. The most significant factor influencing amount and frequency of therapy provided was the time therapists routinely spent, individually and collectively, in information exchange. Patient factors, including fatigue and tolerance influenced therapists’ decisions about frequency and intensity, typically resulting in adaptation of therapy rather than no provision. Limited use of individual patient therapy timetables was evident. Therapist staffing levels were associated with differences in therapy provision but were not the main determinant of intensity and frequency. Few therapists demonstrated understanding of the evidence underpinning recommendations for increased therapy frequency and intensity. Units delivering more therapy had undertaken patient-focused reorganisation of therapists’ working practices, enabling them to provide therapy consistent with guideline recommendations. Conclusion: Time spent in information exchange impacted on therapy provision in stroke units. Reorganisation of therapists’ work improved alignment with guidelines.
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15. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
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Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, Forster, Anne, Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, and Forster, Anne
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Objective: To identify why the National Clinical Guideline recommendation of 45 minutes of each appropriate therapy daily is not met in many English stroke units. Design: Mixed-methods case-study evaluation, including modified process mapping, non-participant observations of service organisation and therapy delivery, documentary analysis and semi-structured interviews. Setting: Eight stroke units in four English regions. Subjects: Seventy-seven patients with stroke, 53 carers and 197 stroke unit staff were observed; 49 patients, 50 carers and 131 staff participants were interviewed. Results: Over 1000 hours of non-participant observations and 433 patient-specific therapy observations were undertaken. The most significant factor influencing amount and frequency of therapy provided was the time therapists routinely spent, individually and collectively, in information exchange. Patient factors, including fatigue and tolerance influenced therapists’ decisions about frequency and intensity, typically resulting in adaptation of therapy rather than no provision. Limited use of individual patient therapy timetables was evident. Therapist staffing levels were associated with differences in therapy provision but were not the main determinant of intensity and frequency. Few therapists demonstrated understanding of the evidence underpinning recommendations for increased therapy frequency and intensity. Units delivering more therapy had undertaken patient-focused reorganisation of therapists’ working practices, enabling them to provide therapy consistent with guideline recommendations. Conclusion: Time spent in information exchange impacted on therapy provision in stroke units. Reorganisation of therapists’ work improved alignment with guidelines.
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16. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
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Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, Forster, Anne, Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, and Forster, Anne
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Objective: To identify why the National Clinical Guideline recommendation of 45 minutes of each appropriate therapy daily is not met in many English stroke units. Design: Mixed-methods case-study evaluation, including modified process mapping, non-participant observations of service organisation and therapy delivery, documentary analysis and semi-structured interviews. Setting: Eight stroke units in four English regions. Subjects: Seventy-seven patients with stroke, 53 carers and 197 stroke unit staff were observed; 49 patients, 50 carers and 131 staff participants were interviewed. Results: Over 1000 hours of non-participant observations and 433 patient-specific therapy observations were undertaken. The most significant factor influencing amount and frequency of therapy provided was the time therapists routinely spent, individually and collectively, in information exchange. Patient factors, including fatigue and tolerance influenced therapists’ decisions about frequency and intensity, typically resulting in adaptation of therapy rather than no provision. Limited use of individual patient therapy timetables was evident. Therapist staffing levels were associated with differences in therapy provision but were not the main determinant of intensity and frequency. Few therapists demonstrated understanding of the evidence underpinning recommendations for increased therapy frequency and intensity. Units delivering more therapy had undertaken patient-focused reorganisation of therapists’ working practices, enabling them to provide therapy consistent with guideline recommendations. Conclusion: Time spent in information exchange impacted on therapy provision in stroke units. Reorganisation of therapists’ work improved alignment with guidelines.
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17. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
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Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, Forster, Anne, Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, and Forster, Anne
- Abstract
Objective: To identify why the National Clinical Guideline recommendation of 45 minutes of each appropriate therapy daily is not met in many English stroke units. Design: Mixed-methods case-study evaluation, including modified process mapping, non-participant observations of service organisation and therapy delivery, documentary analysis and semi-structured interviews. Setting: Eight stroke units in four English regions. Subjects: Seventy-seven patients with stroke, 53 carers and 197 stroke unit staff were observed; 49 patients, 50 carers and 131 staff participants were interviewed. Results: Over 1000 hours of non-participant observations and 433 patient-specific therapy observations were undertaken. The most significant factor influencing amount and frequency of therapy provided was the time therapists routinely spent, individually and collectively, in information exchange. Patient factors, including fatigue and tolerance influenced therapists’ decisions about frequency and intensity, typically resulting in adaptation of therapy rather than no provision. Limited use of individual patient therapy timetables was evident. Therapist staffing levels were associated with differences in therapy provision but were not the main determinant of intensity and frequency. Few therapists demonstrated understanding of the evidence underpinning recommendations for increased therapy frequency and intensity. Units delivering more therapy had undertaken patient-focused reorganisation of therapists’ working practices, enabling them to provide therapy consistent with guideline recommendations. Conclusion: Time spent in information exchange impacted on therapy provision in stroke units. Reorganisation of therapists’ work improved alignment with guidelines.
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- View/download PDF
18. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units
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Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, Forster, Anne, Clarke, David, Burton, Louisa-Jane, Tyson, Sarah F., Rogers, Helen, Drummond, Avril E.R., Palmer, Rebecca, Hoffmann, Alex, Prescott, Matthew, Tyrrell, Pippa, Brkic, Lianne, and Forster, Anne
- Abstract
Objective: To identify why the National Clinical Guideline recommendation of 45 minutes of each appropriate therapy daily is not met in many English stroke units. Design: Mixed-methods case-study evaluation, including modified process mapping, non-participant observations of service organisation and therapy delivery, documentary analysis and semi-structured interviews. Setting: Eight stroke units in four English regions. Subjects: Seventy-seven patients with stroke, 53 carers and 197 stroke unit staff were observed; 49 patients, 50 carers and 131 staff participants were interviewed. Results: Over 1000 hours of non-participant observations and 433 patient-specific therapy observations were undertaken. The most significant factor influencing amount and frequency of therapy provided was the time therapists routinely spent, individually and collectively, in information exchange. Patient factors, including fatigue and tolerance influenced therapists’ decisions about frequency and intensity, typically resulting in adaptation of therapy rather than no provision. Limited use of individual patient therapy timetables was evident. Therapist staffing levels were associated with differences in therapy provision but were not the main determinant of intensity and frequency. Few therapists demonstrated understanding of the evidence underpinning recommendations for increased therapy frequency and intensity. Units delivering more therapy had undertaken patient-focused reorganisation of therapists’ working practices, enabling them to provide therapy consistent with guideline recommendations. Conclusion: Time spent in information exchange impacted on therapy provision in stroke units. Reorganisation of therapists’ work improved alignment with guidelines.
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19. An intervention to support stroke survivors and their carers in the longer term (LoTS2Care): study protocol for the process evaluation of a cluster randomised controlled feasibility trial.
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on behalf of the LoTS2Care Programme Management Group, Hardicre, Natasha K., Crocker, Thomas F, Wright, Alan, Burton, Louisa-Jane, Ozer, Seline, Atkinson, Ross, Forster, Anne, House, Allan, Hewison, Jenny, McKevitt, Christopher, Farrin, Amanda J., and LoTS2Care Programme Management Group
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HEALTH care intervention (Social services) ,STROKE patients ,HEALTH outcome assessment ,QUALITY of life ,CAREGIVER education ,RANDOMIZED controlled trials - Abstract
Background: Whilst pathways relating to the early stages of stroke care have become well established, strategies for longer-term care are less developed and longer-term outcomes remain poor for many stroke survivors. New Start, a complex intervention that includes needs identification, exploration of social networks and components of problem-solving and self-management, was designed to improve stroke survivors' quality of life by addressing unmet needs and increasing participation. It is delivered approximately 6 months post-stroke by trained staff (facilitators). We are currently undertaking a cluster randomised feasibility trial of the New Start intervention with an embedded process evaluation, which is an important component of the design and testing of complex interventions as it provides an understanding of how interventions are delivered and function in different settings.Methods/design: This mixed methods process evaluation will explore the degree to which New Start is implemented as intended, the impact of context on intervention delivery and the acceptability of the intervention for stroke survivors, their families and practitioners. It will include non-participant observation of facilitator training and intervention delivery. Interviews with stroke survivors, facilitators and other relevant staff (including administrators and managerial staff) will be undertaken. Qualitative data from interview transcripts, facilitator reflections and observational field notes will be analysed thematically alongside numerical data documenting intervention delivery collected as part of the trial.Discussion: This process evaluation will identify factors that aid and impede implementation of the New Start intervention and improve understanding of this novel approach to longer-term stroke care.Trial Registration: ISRCTN Registry, ISRCTN38920246 . Registered on 22 June 2016. [ABSTRACT FROM AUTHOR]- Published
- 2018
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20. Longer-term health and social care strategies for stroke survivors and their carers: the LoTS2Care research programme including cluster feasibility RCT
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Forster A, Ozer S, Crocker TF, House A, Hewison J, Roberts E, Dickerson J, Carter G, Hulme C, Fay M, Richardson G, Wright A, McKevitt C, McEachan R, Foy R, Barnard L, Moreau L, Prashar A, Clarke D, Hardicre N, Holloway I, Brindle R, Hall J, Burton LJ, Atkinson R, Hawkins RJ, Brown L, Cornwall N, Dawkins B, Meads D, Schmitt L, Fletcher M, Speed M, Grenfell K, Hartley S, Young J, and Farrin A
- Abstract
Background: It is reported that the longer-term outcomes for stroke survivors are poor, with a range of unmet needs identified., Objectives: The aims were to develop and test a longer-term stroke care strategy focused on improving the quality of life of stroke survivors and their carers by addressing unmet needs, and maintenance and enhancement of participation (i.e. involvement in life situations)., Design: Five overlapping workstreams were undertaken – (1) refinement of content by semistructured interviews with stroke survivors and their carers and by a review of the literature to inform content and delivery of the care strategy; (2) exploration of service models by national survey and focus groups with purposely selected services; (3) intervention development by interaction with a reference group of stroke survivors, carers, and health and social care professionals; (4) refinement and pilot implementation of the developed intervention in three stroke services (case studies); and (5) a cluster randomised controlled feasibility trial in 10 stroke services across England and Wales., Setting: The intervention development work and feasibility trial were in stroke services (inclusive of primary, secondary, community and social care provision) across England and Wales., Participants: Participants were stroke survivors resident in the community and their carers, and health and social care professionals in the included stroke services., Data Sources: Interviews with 28 stroke survivors and their carers at least 9 months post stroke ascertained their needs and the barriers to and facilitators of addressing those needs. Additional literature reviews identified 23 needs. No evidence-based interventions to address these needs were reported; self-management was highlighted as a possible delivery mechanism. In workstream 2, a national survey revealed that the most common model of stroke service provision was care up to 12 months post stroke, reported by 46 (40%) services. Thirty-five (30%) services provided care up to 6 months post stroke and 35 (30%) provided care beyond 12 months, thus identifying 6 months post stroke as an appropriate delivery point for a new intervention. Through focus groups in a range of services, stroke survivors’ perceived unmet needs and the barriers to and enablers of service provision were identified., Intervention: Using information obtained in workstreams 1 and 2 and working closely with a stakeholder reference group, we developed an intervention based on the unmet needs prioritised by stroke survivors and their carers (workstream 3). In workstream 4, action groups (clinicians, stroke survivors and researchers) were established in three stroke services that led implementation in their service and contributed to the iterative refinement of the intervention, associated training programme and implementation materials. The intervention (called New Start) was delivered at 6 months post stroke. Key components were problem-solving self-management with survivors and carers, help with obtaining usable information, and helping survivors and their carers build sustainable, flexible support networks., Results: A cluster randomised feasibility trial (workstream 5) was successfully implemented in 10 stroke services across England and Wales, with associated process and health economic evaluations. Five services were randomised to provide New Start, while five continued with usual care; 269 participants were recruited. Progression criteria – in terms of our pre-determined (red, amber, green) criteria for progress to a full trial: target stroke survivor recruitment rates were achieved, on average, across sites (24.1 per site over 6 months, green); 216 (80.3%) registered stroke survivors returned follow-up questionnaires at 9 months (84.1% in the intervention arm and 75.8% in the usual care arm, green); according to data reported by sites, overall, 95.2% of registered stroke survivors were offered at least one session of the intervention (green); all five intervention sites had at least two facilitators deemed competent, delivered the New Start intervention and provided it to stroke survivors (green). However, at some sites, there were concerns regarding the number of stroke survivors being offered, accepting and receiving the intervention. Only small differences in outcomes and costs were observed between the New Start and usual care groups, and considerable uncertainty around the cost-effectiveness remains., Conclusions: We report a complex programme of work that has described the longer-term needs of stroke survivors and highlighted evidence and service gaps. Working closely with stroke survivors, an intervention was developed that has been refined in three services and feasibility tested in a cluster randomised controlled trial. Further refinement of the target population and optimisation of the intervention materials is required prior to a full randomised controlled trial evaluation., Future Work: Optimisation of the intervention, and clearer specification of recipients, are required prior to a full trial evaluation., Trial Registration: Current Controlled Trials ISRCTN38920246., Funding: This project was funded by the National Institute for Health Research (NIHR) Programme Grants for Applied Research programme and will be published in full in Programme Grants for Applied Research ; Vol. 9, No. 3. See the NIHR Journals Library website for further project information., (Copyright © Queen’s Printer and Controller of HMSO 2021. This work was produced by Forster et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.)
- Published
- 2021
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