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3. Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial

Author

Fillitz, Michael, Knoebl, Paul, Meers, Stef, Amine, Ismail Mohamad, Gumulec, Jaromir, Hlusi, Antonin, Mayer, Jiri, Quittet, Philippe, Viallard, Jean-Francois, Betaneli, Magdana, Datikashvili-David, Irine, Iosava, Genadi, Makhaldiani, Levan, Rejto, Laszlo, Sharashenidze, Nino, Groepper, Stefanie, Röth, Alexander, Hamed, Aryan, Illes, Arpad, Carpenedo, Monica, Artoni, Andrea, Bocchia, Monica, Gamberi, Barbara, Borchiellini, Alessandra, Oliva, Esther Natalie, Patriarca, Andrea, Tomassetti, Simona, Miyakawa, Yoshitaka, Ando, Kiyoshi, Handa, Hiroshi, Katsutani, Shinya, Nishiwaki, Kaichi, Ito, Shoko, Ito, Tomoki, de Boer, Fransien, Jansen, A.J. Gerard, Ciepluch, Hanna, Fornagiel, Szymon, Grosicki, Sebastian, Soroka-Wojtaszko, Maria, Trelinski, Jacek, Bakirov, Bulat, Borisenkova, Elena, Volodicheva, Elena, Shatokhin, Yuri, Proydakov, Andrey, Alonso, Maria Aranzazu, Mingot-Castellano, María Eva, Sanchez-Gonzalez, Blanca, Valcarcel Ferreiras, David, Ayli, Meltem, Hacibekiroglu, Tuba, Demir, Ahmet Muzaffer, Nalçaci, Meliha, Sonmez, Mehmet, Tombak, Anil, Toprak, Selami Kocak, Turgut, Burhan, Vural, Filiz, Yagci, Munci, Altuntas, Fevzi, Turgut, Mehmet, Kaya, Emin, Romanyuk, Nataliya, McDonald, Vickie, Kazmi, Syed Rashid Saeed, Broome, Catherine, Cataland, Spero, Doshi, Ketan, Lentz, Steven R., Boxer, Michael, Rosenberg, Richard, Broome, Catherine M, Kuter, David J, Al-Samkari, Hanny, Bussel, James B, Godar, Marie, Ayguasanosa, Jaume, De Beuf, Kristof, Rodeghiero, Francesco, Michel, Marc, and Newland, Adrian

Published
2023
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4. The role of CD8+ T-cell clones in immune thrombocytopenia

Author

Malik, Amna, Sayed, Anwar A., Han, Panpan, Tan, Michelle M. H., Watt, Eleanor, Constantinescu-Bercu, Adela, Cocker, Alexander T. H., Khoder, Ahmad, Saputil, Rocel C., Thorley, Emma, Teklemichael, Ariam, Ding, Yunchuan, Hart, Alice C. J., Zhang, Haiyu, Mitchell, Wayne A., Imami, Nesrina, Crawley, James T. B., Salles-Crawley, Isabelle I., Bussel, James B., Zehnder, James L., Adams, Stuart, Zhang, Bing M., and Cooper, Nichola

Published
2023
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5. Longitudinal study of 2 patients with cyclic thrombocytopenia, STAT3 and MPL mutations

Author

Zhang, Haiyu, Chien, May, Hou, Yu, Shomali, William, Brar, Rondeep S., Ho, Chandler, Han, Panpan, Xu, Danfei, Zhang, Bing M., Guo, Xiangqian, Tolentino, Lorna L., Wu, Nancy C., Tsai, Albert G., Jin, Jing, Witteles, Wesley H., Chen, Zhenping, Abidi, Parveen, Jangam, Diwash, Krieger, Madison S., Craig, Morgan, Bussel, James B., Gotlib, Jason R., and Zehnder, James L.

Published
2023
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6. SARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP

Author

Lee, Eun-Ju, Beltrami-Moreira, Marina, Al-Samkari, Hanny, Cuker, Adam, DiRaimo, Jennifer, Gernsheimer, Terry, Kruse, Alexandra, Kessler, Craig, Kruse, Caroline, Leavitt, Andrew D., Lee, Alfred I., Liebman, Howard A., Newland, Adrian C., Ray, Ashley E., Tarantino, Michael D., Thachil, Jecko, Kuter, David J., Cines, Douglas B., and Bussel, James B.

Published
2022
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9. List of contributors

Author

Abdel-Azim, Hisham, primary, Acharya, Suchitra S., additional, Agrawal, Anurag K., additional, Al-Ghafry, Maha, additional, Allen, Carl E., additional, Amin, Seema, additional, Atlas, Mark P., additional, Bagatell, Rochelle, additional, Blanc, Lionel, additional, Blei, Francine, additional, Bussel, James B., additional, Carroll, William L., additional, Connelly, James A., additional, Dome, Jeffrey S., additional, Dulmovits, Brian M., additional, Eckstein, Olive S., additional, Elgarten, Caitlin W., additional, Elghetany, Mohamed Tarek, additional, Federman, Noah, additional, Fein Levy, Carolyn, additional, Feusner, James, additional, Fish, Jonathan D., additional, Fonseca, Adriana, additional, Freedman, Jason L., additional, Friedman, Debra L., additional, Hanson, Derek, additional, Hijiya, Nobuko, additional, Hofmann, Inga, additional, Huang, Mary S., additional, Iacobas, Ionela, additional, Josephson, Cassandra D., additional, Kessel, Rachel, additional, Khandros, Eugene, additional, Krystal, Julie, additional, Kwiatkowski, Janet L., additional, Lanzkowsky, Philip, additional, Leahey, Ann, additional, Lipton, Jeffrey M., additional, McGuinn, Catherine, additional, Mody, Rajen J., additional, Nadel, Amy, additional, Nash, Michelle, additional, Niss, Omar, additional, Olson, Thomas A., additional, Pillai, Pallavi M., additional, Powers, Jacquelyn M., additional, Prchal, Josef T., additional, Pulsipher, Michael A., additional, Quinn, Charles T., additional, Radinsky, Miriam, additional, Redner, Arlene, additional, Rheingold, Susan R., additional, Sarangi, Susmita N., additional, Shah, Amish, additional, Shavit, Jordan A., additional, Smith, Christine M., additional, Sokol, Elizabeth, additional, Sutton, Kathryn S., additional, Tashi, Tsewang, additional, Teachey, David T., additional, Vagrecha, Anshul, additional, Vlachos, Adrianna, additional, Walkovich, Kelly, additional, Warwick, Anne B., additional, Weinstein, Howard J., additional, Winsnes, Katrina, additional, and Wolfe, Lawrence C., additional

Published
2022
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20. Updated international consensus report on the investigation and management of primary immune thrombocytopenia

Author

Provan, Drew, Arnold, Donald M., Bussel, James B., Chong, Beng H., Cooper, Nichola, Gernsheimer, Terry, Ghanima, Waleed, Godeau, Bertrand, González-López, Tomás José, Grainger, John, Hou, Ming, Kruse, Caroline, McDonald, Vickie, Michel, Marc, Newland, Adrian C., Pavord, Sue, Rodeghiero, Francesco, Scully, Marie, Tomiyama, Yoshiaki, Wong, Raymond S., Zaja, Francesco, and Kuter, David J.

Published
2019
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23. The highs and lows of cyclic thrombocytopenia.

Author

Zhang, Haiyu, Villar‐Prados, Alejandro, Bussel, James B., and Zehnder, James L.

Subjects
PLATELET count, THROMBOCYTOPENIA, AUTOIMMUNE diseases, IDIOPATHIC thrombocytopenic purpura, THROMBOPOIETIN, THERAPEUTICS
Abstract

Summary: Cyclic thrombocytopenia (CTP) is characterized by periodic platelet oscillation with substantial amplitude. Most CTP cases have a thrombocytopenic background and are often misdiagnosed as immune thrombocytopenia with erratically effective treatment choices. CTP also occurs during hydroxyurea treatment in patients with myeloproliferative diseases. While the aetiology of CTP remains uncertain, here we evaluate historical, theoretical and clinical findings to provide a framework for understanding CTP pathophysiology. CTP retains the intrinsic oscillatory factors defined by the homeostatic regulation of platelet count, presenting as reciprocal platelet/thrombopoietin oscillations and stable oscillation periodicity. Moreover, CTP patients possess pathogenic factors destabilizing the platelet homeostatic system thereby creating opportunities for external perturbations to initiate and sustain the exaggerated platelet oscillations. Beyond humoral and cell‐mediated autoimmunity, we propose recently uncovered germline and somatic genetic variants, such as those of MPL, STAT3 or DNMT3A, as pathogenic factors in thrombocytopenia‐related CTP. Likewise, the JAK2 V617F or BCR::ABL1 translocation that drives underlying myeloproliferative diseases may also play a pathogenic role in hydroxyurea‐induced CTP, where hydroxyurea treatment can serve as both a trigger and a pathogenic factor of platelet oscillation. Elucidating the pathogenic landscape of CTP provides an opportunity for targeted therapeutic approaches in the future. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial

Author

Broome, Catherine M, primary, McDonald, Vickie, additional, Miyakawa, Yoshitaka, additional, Carpenedo, Monica, additional, Kuter, David J, additional, Al-Samkari, Hanny, additional, Bussel, James B, additional, Godar, Marie, additional, Ayguasanosa, Jaume, additional, De Beuf, Kristof, additional, Rodeghiero, Francesco, additional, Michel, Marc, additional, Newland, Adrian, additional, Fillitz, Michael, additional, Knoebl, Paul, additional, Meers, Stef, additional, Amine, Ismail Mohamad, additional, Gumulec, Jaromir, additional, Hlusi, Antonin, additional, Mayer, Jiri, additional, Quittet, Philippe, additional, Viallard, Jean-Francois, additional, Betaneli, Magdana, additional, Datikashvili-David, Irine, additional, Iosava, Genadi, additional, Makhaldiani, Levan, additional, Rejto, Laszlo, additional, Sharashenidze, Nino, additional, Groepper, Stefanie, additional, Röth, Alexander, additional, Hamed, Aryan, additional, Illes, Arpad, additional, Artoni, Andrea, additional, Bocchia, Monica, additional, Gamberi, Barbara, additional, Borchiellini, Alessandra, additional, Oliva, Esther Natalie, additional, Patriarca, Andrea, additional, Tomassetti, Simona, additional, Ando, Kiyoshi, additional, Handa, Hiroshi, additional, Katsutani, Shinya, additional, Nishiwaki, Kaichi, additional, Ito, Shoko, additional, Ito, Tomoki, additional, de Boer, Fransien, additional, Jansen, A.J. Gerard, additional, Ciepluch, Hanna, additional, Fornagiel, Szymon, additional, Grosicki, Sebastian, additional, Soroka-Wojtaszko, Maria, additional, Trelinski, Jacek, additional, Bakirov, Bulat, additional, Borisenkova, Elena, additional, Volodicheva, Elena, additional, Shatokhin, Yuri, additional, Proydakov, Andrey, additional, Alonso, Maria Aranzazu, additional, Mingot-Castellano, María Eva, additional, Sanchez-Gonzalez, Blanca, additional, Valcarcel Ferreiras, David, additional, Ayli, Meltem, additional, Hacibekiroglu, Tuba, additional, Demir, Ahmet Muzaffer, additional, Nalçaci, Meliha, additional, Sonmez, Mehmet, additional, Tombak, Anil, additional, Toprak, Selami Kocak, additional, Turgut, Burhan, additional, Vural, Filiz, additional, Yagci, Munci, additional, Altuntas, Fevzi, additional, Turgut, Mehmet, additional, Kaya, Emin, additional, Romanyuk, Nataliya, additional, Kazmi, Syed Rashid Saeed, additional, Broome, Catherine, additional, Cataland, Spero, additional, Doshi, Ketan, additional, Lentz, Steven R., additional, Boxer, Michael, additional, and Rosenberg, Richard, additional

Published
2023
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28. List of Contributors

Author

Abramson, Jakub, primary, Ahmed, S. Sohail, additional, Alba, Marco A., additional, Ali, Youssif M., additional, Ambrus, Julian L., additional, Andersson Svärd, Agnes, additional, Aringer, Martin, additional, Assassi, Shervin, additional, Aung, Thanda, additional, Ayzenberg, Ilya, additional, Barker, Robert N., additional, Baxter, Alan G., additional, Betterle, Corrado, additional, Birlea, Stanca A., additional, Björkström, Niklas K., additional, Blair, Paul A., additional, Blüml, Stephan, additional, Bosch, Xavier, additional, Brodsky, Robert A., additional, Bryceson, Yenan T., additional, Burkett, Patrick R., additional, Bussel, James B., additional, Caricchio, Roberto, additional, Casciola-Rosen, Livia, additional, Caturegli, Patrizio, additional, Chaigne-Delalande, Benjamin, additional, Chalan, Paulina, additional, Chatenoud, Lucienne, additional, Cohen, Philip L., additional, Cooper, Megan A., additional, Coppieters, Ken, additional, Crystal, Ronald G., additional, Culton, Donna A., additional, Damato, Valentina, additional, Davidson, Anne, additional, Delfino, Lorenzo, additional, Delves, Peter J., additional, Di Dalmazi, Giulia, additional, Diamond, Betty, additional, Diaz, Luis A., additional, Falk, Ronald J., additional, Fritzler, Marvin J., additional, Gallucci, Stefania, additional, Gangaputra, Sapna, additional, Gelbman, Brian, additional, Gershwin, M. Eric, additional, Gery, Igal, additional, Getts, Daniel R., additional, Gold, Ralf, additional, Goldfarb, Yael, additional, Gong, Jing, additional, Gordon, Siamon, additional, Goronzy, Jörg J., additional, Greer, Judith M., additional, Guazzone, Vanesa A., additional, Guilherme, Luiza, additional, Hafler, David A., additional, Hahn, Bevra H., additional, Hamad, Abdel Rahim A., additional, Hamano, Hideaki, additional, Harrison, Leonard C., additional, Homann, Dirk, additional, Husebye, Eystein S., additional, Jennette, J. Charles, additional, Jones, Richard J., additional, Jordan, Margaret A., additional, Kalil, Jorge, additional, Kawa, Shigeyuki, additional, Kaya, Ziya, additional, Keller, Christian W., additional, King, Nicholas J.C., additional, Kitcharoensakkul, Maleewan, additional, Kiyosawa, Kendo, additional, Königs, Christoph, additional, Kronenberg, Mitchell, additional, Kuchroo, Vijay K., additional, Laurence, Arian, additional, Lee, Eun-Ju, additional, Lehmann, Helmar C., additional, Lernmark, Åke, additional, Lindbladh, Ida, additional, Liu, Zhi, additional, Ljunggren, Hans-Gustaf, additional, Lunardi, Claudio, additional, Lundin, Knut E.A., additional, Lünemann, Jan D., additional, Lunn, Michael P.T., additional, Lustig, Livia, additional, Mackay, Charles R., additional, Mackay, Ian R., additional, Malattia, Clara, additional, Martinez-Pomares, Luisa, additional, Martini, Alberto, additional, Mauri, Claudia, additional, McCombe, Pamela A., additional, Melchers, Fritz, additional, Mieli-Vergani, Giorgina, additional, Miller, Frederick W., additional, Miller, Stephen D., additional, Mizui, Masayuki, additional, Mjösberg, Jenny, additional, Münz, Christian, additional, Nijjar, Jagtar Singh, additional, Norris, David A., additional, Oleinika, Kristine, additional, Oppenheim, Joost J., additional, Pawlak, Mathias, additional, Peligero-Cruz, Cristina, additional, Peters, Anneli, additional, Peterson, Pärt, additional, Pitarokoili, Kalliopi, additional, Presotto, Fabio, additional, Puccetti, Antonio, additional, Rabb, Hamid, additional, Raczek, Patricia, additional, Rahman, M. Jubayer, additional, Ramos-Casals, Manuel, additional, Rose, Noel R., additional, Rosen, Antony, additional, Sadasivam, Mohanraj, additional, Schiffenbauer, Adam, additional, Schwaeble, Wilhelm J., additional, Sen, H. Nida, additional, Serota, Marc, additional, Sheikh, Kazim A., additional, Shoenfeld, Yehuda, additional, Shovman, Ora, additional, Sieper, Joachim, additional, Silverstein, Arthur M., additional, Sim, Robert B., additional, Smith, Kenneth G C, additional, Smolen, Josef S., additional, Sollid, Ludvig M., additional, Spiteri, Alanna, additional, Steinman, Lawrence, additional, Stone, John H., additional, Syrbe, Uta, additional, Tamhaney, Ami, additional, Tanaka, Atsushi, additional, Taneja, Veena, additional, Tarbell, Kristin V., additional, Tinazzi, Elisa, additional, Tiong, Benedict K., additional, Toh, Ban-Hock, additional, Tsokos, George C., additional, Tung, Kenneth S.K., additional, Varga, John, additional, Vergani, Diego, additional, Vickers, Mark A., additional, Viegas, Stuart, additional, Vincent, Angela, additional, von Herrath, Matthias, additional, Weetman, Anthony P., additional, Weinstock, Joel V., additional, Wentworth, John M., additional, Wesley, Sarah, additional, Weyand, Cornelia M., additional, Wingender, Gerhard, additional, Winter, Michael W., additional, Zanchetta, Renato, additional, and Zouali, Moncef, additional

Published
2020
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37. Complement activation negatively affects the platelet response to thrombopoietin receptor agonists in patients with immune thrombocytopenia: a prospective cohort study.

Author

Åkesson, Alexander, Bussel, James B., Martin, Myriam, Blom, Anna M., Klintman, Jenny, Ghanima, Waleed, Zetterberg, Eva, and Garabet, Lamya

Subjects
*THROMBOPOIETIN receptor agonists, *IDIOPATHIC thrombocytopenic purpura, *COMPLEMENT activation, *BLOOD platelets, *PLATELET count
Abstract

Increased platelet destruction is central in the pathogenesis of immune thrombocytopenia. However, impaired platelet production is also relevant and its significance underlies the rationale for treatment with thrombopoietin receptor agonists (TPO-RAs). Previous studies have associated enhanced complement activation with increased disease severity. Additionally, treatment refractoriness has been demonstrated to resolve by the administration of complement-targeted therapeutics in a subset of patients. The association between complement activation and the platelet response to TPO-RA therapy has previously not been investigated. In this study, blood samples from patients with immune thrombocytopenia (n = 15) were prospectively collected before and two, six and 12 weeks after the initiation of TPORA therapy. Plasma levels of complement degradation product C4d and soluble terminal complement complexes were assessed. Patients with significantly elevated baseline levels of terminal complement complexes exhibited more often an inadequate platelet response (p = .04), were exclusively subjected to rescue therapy with intravenous immunoglobulin (p = .02), and did not respond with a significant platelet count increase during the study period. C4d showed a significant (p = .01) ability to distinguish samples with significant terminal complement activation, implying engagement of the classical complement pathway. In conclusion, elevated levels of complement biomarkers were associated with a worse TPO-RA treatment response. Larger studies are needed to confirm these results. Biomarkers of complement activation may prove valuable as a prognostic tool to predict which patients that potentially could benefit from complement-inhibiting therapy in the future. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Contributors

Author

Alsousou, Joseph, primary, Angiolillo, Dominick J., additional, Arachiche, Amal, additional, Aster, Richard H., additional, Barbui, Tiziano, additional, Basili, Stefania, additional, Battinelli, Elisabeth M., additional, Bavry, Anthony A., additional, Bergmeier, Wolfgang, additional, Bertrand, Gerald, additional, Bhatt, Deepak L., additional, Blair, Thomas A., additional, Bledzka, Kamila, additional, Borst, Oliver, additional, Bouck, Emma G., additional, Brass, Lawrence F., additional, Bray, Paul F., additional, Briggs, Carol, additional, Brzoska, Tomasz, additional, Bussel, James B., additional, Cattaneo, Marco, additional, Chakravorty, Subarna, additional, Chan, Noel C., additional, Chaturvedi, Shruti, additional, Chong, Beng H., additional, Clemetson, Kenneth J., additional, Clemetson, Jeannine M., additional, Coller, Barry S., additional, del Zoppo, Gregory J., additional, Despotovic, Jenny M., additional, Diamond, Scott L., additional, Easton, J. Donald, additional, Eto, Koji, additional, Falet, Hervé, additional, Ferrer-Marin, Francisca, additional, Finazzi, Guido, additional, Flaumenhaft, Robert, additional, Freedman, Jane E., additional, Frelinger, Andrew L., additional, Freson, Kathleen, additional, Gasecka, Aleksandra, additional, Gawaz, Meinrad, additional, Giannini, Silvia, additional, Greinacher, Andreas, additional, Gremmel, Thomas, additional, Gurbel, Paul A., additional, Haining, Elizabeth J., additional, Han, Xu, additional, Harrison, Paul, additional, Hayward, Catherine P.M., additional, Hoffmeister, Karin, additional, Hvas, Anne-Mette, additional, Israels, Sara J., additional, Italiano, Joseph E., additional, Jeong, Young-Hoon, additional, Johnson, Andrew D., additional, Kaplan, Cecile, additional, Karagiannis, Peter, additional, Kato, Gregory J., additional, Kemble, Samuel, additional, Kolandaivelu, Kumaran, additional, Koupenova, Milka, additional, Kuter, David J., additional, Lambert, Michele P., additional, Lee, Robert H., additional, Levin, Jack, additional, Li, Renhao, additional, Li, Zhenyu, additional, Li, Zihai, additional, Li, Anqi, additional, Liani, Rossella, additional, Lordkipanidzé, Marie, additional, Lorenz, Viola, additional, Machlus, Kellie R., additional, Mahtta, Dhruv, additional, Mannucci, Pier Mannuccio, additional, McCrae, Keith R., additional, Metelli, Alessandra, additional, Michelson, Alan D., additional, Moffat, Karen A., additional, Moon, Jae Youn, additional, Morrissey, James H., additional, Mutch, Nicola J., additional, Nagy, Zoltan, additional, Ni, Heyu, additional, Nicolson, Phillip L.R., additional, Nieman, Marvin T., additional, Nieuwland, Rienk, additional, Onselaer, Marie-Blanche, additional, Patrono, Carlo, additional, Plow, Edward F., additional, Poncz, Mortimer, additional, Poon, Man-Chiu, additional, Poulter, Natalie S., additional, Poventud-Fuentes, Izmarie, additional, Provost, Patrick, additional, Qin, Jun, additional, Rayes, Julie, additional, Reiner, Alexander P., additional, Riesenberg, Brian, additional, Roberts, Irene A.G., additional, Rondina, Matthew T., additional, Rowley, Jesse W., additional, Santilli, Francesca, additional, Scharf, Rüdiger E., additional, Senis, Yotis A., additional, Sharda, Anish, additional, Siddon, Alexa J., additional, Siljander, Pia R.-M., additional, Tricoci, Pierluigi, additional, Simeone, Paola, additional, Smith, Stephanie A., additional, Smyth, Susan S., additional, Snyder, Edward L., additional, Sola-Visner, Martha, additional, Stalker, Timothy J., additional, Stefanini, Lucia, additional, Sugimoto, Naoshi, additional, Sundd, Prithu, additional, Tantry, Udaya S., additional, Tefferi, Ayalew, additional, Thomas, Steven G., additional, Thomas, Mark R., additional, Tomaiuolo, Maurizio, additional, Tormey, Christopher A., additional, Tsai, Han-Mou, additional, Violi, Francesco, additional, Warkentin, Theodore E., additional, Watson, Steve P., additional, Weitz, Jeffrey I., additional, Welsh, John, additional, Weyrich, Andrew S., additional, Wilcox, David A., additional, Wu, Bill X., additional, Yeaman, Michael R., additional, Zhu, Li, additional, Zimmerman, Guy A., additional, and Zunica, Elizabeth R., additional

Published
2019
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40. List of Contributors

Author

Acharya, Suchitra S., primary, Aeschlimann, Judith, additional, Al-Huniti, Ahmad, additional, Antun, Ana G., additional, Arinsburg, Suzanne A., additional, Avecilla, Scott T., additional, Bahar, Burak, additional, Bailey, Debra Jo, additional, Batsuli, Glaivy, additional, Billett, Henny H., additional, Bloch, Evan M., additional, Briones, Michael A., additional, Bussel, James B., additional, Carden, Marcus A., additional, Chandler, Wayne L., additional, Chen, Dong, additional, Csete, Marie, additional, Cuker, Adam, additional, Cushing, Melissa M., additional, Davila, Jennifer, additional, DeSimone, Robert A., additional, Dodd, Roger Y., additional, Dunbar, Nancy M., additional, Dunn, Amy L., additional, Erdman, Patrick A., additional, Francischetti, Ivo M.B., additional, Francis, Richard O., additional, Ginzburg, Yelena Z., additional, Godbey, Elizabeth A., additional, Goel, Ruchika, additional, Gokhale, Amit, additional, Goldstein, Yitz, additional, Gorlin, Jed B., additional, Goss, Cheryl A., additional, Hamilton, Janis R., additional, Hendrickson, Jeanne E., additional, He, Rong, additional, Hillyer, Christopher D., additional, Hod, Eldad A., additional, Hsu, Yen-Michael S., additional, Hume, Heather A., additional, Jacob, Jack, additional, Jain, Shilpa, additional, Jalikis, Florencia G., additional, Jimenez, Alexandra, additional, Jobe, Shawn M., additional, Josephson, Cassandra D., additional, Karafin, Matthew S., additional, Katz, Louis M., additional, Kempton, Christine L., additional, Kessler, Debra A., additional, Kushnir, Margarita, additional, Lambert, Michele P., additional, Li, Marissa, additional, Manwani, Deepa, additional, Maramica, Irina, additional, Marschner, Susanne, additional, Frenet, Emeline Masson, additional, McGuinn, Catherine E., additional, Meeks, Shannon L., additional, Miller, Connie H., additional, Minniti, Caterina P., additional, Mitchell, William B., additional, Monis, Grace F., additional, Nester, Theresa, additional, Norris, Philip, additional, Novotny, Angela, additional, Paroder-Belenitsky, Monika, additional, Pati, Shibani, additional, Peck, Kim, additional, Pham, Huy P., additional, Pishko, Allyson, additional, Quinley, Eva D., additional, Racine-Brzostek, Sabrina, additional, Rahorst, Lynsi, additional, Rennert, Hanna, additional, Restivo, Joseph S.A., additional, Reyes Gil, Morayma, additional, Rosenbaum-Marinaro, Liz, additional, Roshal, Mikhail, additional, Rutter, Sara, additional, Sachais, Bruce S., additional, Saini, Surbhi, additional, Sarangi, Susmita N., additional, Savage, William J., additional, Scaradavou, Andromachi, additional, Schwartz, Joseph, additional, Seheult, Jansen N., additional, Senaldi, Eric, additional, Shaikh, Salima, additional, Sharathkumar, Anjali, additional, Shaz, Beth H., additional, Shi, Patricia A., additional, Simmons, Sierra C., additional, Staley, Elizabeth M., additional, Storch, Emily K., additional, Strauss, Donna, additional, Tanhehco, Yvette C., additional, Tobian, Aaron A.R., additional, Tormey, Christopher A., additional, Townsend, Mary, additional, Tran, Duc Q., additional, Van Buren, Nancy L., additional, Vege, Sunitha, additional, Velliquette, Randall, additional, Vinchi, Francesca, additional, Weinberg, Rona S., additional, Weisberg, Stuart P., additional, Westhoff, Connie M., additional, White, Michael, additional, Winkler, Anne M., additional, Wolgast, Lucia R., additional, Woods, Kalinda, additional, Dimberg, Lina Y., additional, Yazer, Mark H., additional, Young, Carolyn T., additional, Zerra, Patricia E., additional, and Zimowski, Karen L., additional

Published
2019
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43. A pilot feasibility trial of daily versus every other day oral iron supplementation in patients with iron deficiency anaemia

Author

Lin, Yulia, primary, Del Giudice, M. Elisabeth, additional, Kron, Amie, additional, Meirovich, Harley, additional, Sholzberg, Michelle, additional, Swarup, Vidushi, additional, Huang, Mary, additional, Distefano, Lanis, additional, Anani, Waseem Q., additional, Armali, Chantal, additional, Bussel, James B., additional, and Callum, Jeannie, additional

Published
2023
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44. Rilzabrutinib versus placebo in adults and adolescents with persistent or chronic immune thrombocytopenia: LUNA 3 phase III study

Author

Kuter, David J., primary, Bussel, James B., additional, Ghanima, Waleed, additional, Cooper, Nichola, additional, Gernsheimer, Terry, additional, Lambert, Michele P., additional, Liebman, Howard A., additional, Tarantino, Michael D., additional, Lee, Michelle, additional, Guo, Hailing, additional, and Daak, Ahmed, additional

Published
2023
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47. Eltrombopag for children with chronic immune thrombocytopenia (PETIT2): a randomised, multicentre, placebo-controlled trial

Author

Grainger, John D, Locatelli, Franco, Chotsampancharoen, Thirachit, Donyush, Elena, Pongtanakul, Bunchoo, Komvilaisak, Patcharee, Sosothikul, Darintr, Drelichman, Guillermo, Sirachainan, Nongnuch, Holzhauer, Susanne, Lebedev, Vladimir, Lemons, Richard, Pospisilova, Dagmar, Ramenghi, Ugo, Bussel, James B, Bakshi, Kalpana K, Iyengar, Malini, Chan, Geoffrey W, Chagin, Karen D, Theodore, Dickens, Marcello, Lisa M, and Bailey, Christine K

Published
2015
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50. Eltrombopag for the treatment of children with persistent and chronic immune thrombocytopenia (PETIT): a randomised, multicentre, placebo-controlled study

Author

Bussel, James B, de Miguel, Purificación Garcia, Despotovic, Jenny M, Grainger, John D, Sevilla, Julián, Blanchette, Victor S, Krishnamurti, Lakshmanan, Connor, Philip, David, Michèle, Boayue, Koh B, Matthews, Dana C, Lambert, Michele P, Marcello, Lisa M, Iyengar, Malini, Chan, Geoffrey W, Chagin, Karen D, Theodore, Dickens, Bailey, Christine K, and Bakshi, Kalpana K

Published
2015
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