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445 results on '"Buth, J"'

1. Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine Lung Cancer (nNGM)

Author

Simon, Ronald, Sauter, Guido, Volk, Alexander, Neumann, Jens, Klauschen, Frederick, Weichert, Wilko, Kalhori, Naser, Lüthen, Reinhard, Stöhr, Robert, Schubart, Chistoph, Wacker, Heidemarie, Fuchs, Florian, Hartmann, Nils, Graf, Stefanie, Brandts, Christian, Wild, Peter, Demes, Melanie, Reis, Henning, Rohde, Gernot, Janning, M., Süptitz, J., Albers-Leischner, C., Delpy, P., Tufman, A., Velthaus-Rusik, J.-L., Reck, M., Jung, A., Kauffmann-Guerrero, D., Bonzheim, I., Brändlein, S., Hummel, H.-D., Wiesweg, M., Schildhaus, H.-U., Stratmann, J.A., Sebastian, M., Alt, J., Buth, J., Esposito, I., Berger, J., Tögel, L., Saalfeld, F.C., Wermke, M., Merkelbach-Bruse, S., Hillmer, A.M., Klauschen, F., Bokemeyer, C., Buettner, R., Wolf, J., and Loges, S.

Published
2022
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2. Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years

Author

Powell, J. T., Sweeting, M. J., Ulug, P., Blankensteijn, J. D., Lederle, F. A., Becquemin, J.‐P., Greenhalgh, R. M., Greenhalgh, R. M., Beard, J. D., Buxton, M. J., Brown, L. C., Harris, P. L., Powell, J. T., Rose, J. D. G., Russell, I. T., Sculpher, M. J., Thompson, S. G., Lilford, R.J., Bell, P. R. F., Greenhalgh, R. M., Whitaker, S.C., Poole‐Wilson, the late P.A., Ruckley, C. V., Campbell, W. B., Dean, M. R. E., Ruttley, M. S. T., Coles, E. C., Powell, J. T., Halliday, A., Gibbs, S. J., Brown, L. C., Epstein, D., Sculpher, M. J., Thompson, S. G., Hannon, R. J., Johnston, L., Bradbury, A. W., Henderson, M. J., Parvin, S. D., Shepherd, D. F. C., Greenhalgh, R. M., Mitchell, A. W., Edwards, P. R., Abbott, G. T., Higman, D. J., Vohra, A., Ashley, S., Robottom, C., Wyatt, M. G., Rose, J. D. G., Byrne, D., Edwards, R., Leiberman, D. P., McCarter, D. H., Taylor, P. R., Reidy, J. F., Wilkinson, A. R., Ettles, D. F., Clason, A. E., Leen, G. L. S., Wilson, N. V., Downes, M., Walker, S. R., Lavelle, J. M., Gough, M. J., McPherson, S., Scott, D. J. A., Kessell, D. O., Naylor, R., Sayers, R., Fishwick, N. G., Harris, P. L., Gould, D. A., Walker, M. G., Chalmers, N. C., Garnham, A., Collins, M. A., Beard, J. D., Gaines, P. A., Ashour, M. Y., Uberoi, R., Braithwaite, B., Whitaker, S. C., Davies, J. N., Travis, S., Hamilton, G., Platts, A., Shandall, A., Sullivan, B. A., Sobeh, M., Matson, M., Fox, A. D., Orme, R., Yusef, W., Doyle, T., Horrocks, M., Hardman, J., Blair, P. H. B., Ellis, P. K., Morris, G., Odurny, A., Vohra, R., Duddy, M., Thompson, M., Loosemore, T. M. L., Belli, A. M., Morgan, R., Adiseshiah, M., Brookes, J. A. S., McCollum, C. N., Ashleigh, R., Aukett, M., Baker, S., Barbe, E., Batson, N., Bell, J., Blundell, J., Boardley, D., Boyes, S., Brown, O., Bryce, J., Carmichael, M., Chance, T., Coleman, J., Cosgrove, C., Curran, G., Dennison, T., Devine, C., Dewhirst, N., Errington, B., Farrell, H., Fisher, C., Fulford, P., Gough, M., Graham, C., Hooper, R., Horne, G., Horrocks, L., Hughes, B., Hutchings, T., Ireland, M., Judge, C., Kelly, L., Kemp, J., Kite, A., Kivela, M., Lapworth, M., Lee, C., Linekar, L., Mahmood, A., March, L., Martin, J., Matharu, N., McGuigen, K., Morris‐Vincent, P., Murray, S., Murtagh, A., Owen, G., Ramoutar, V., Rippin, C., Rowley, J., Sinclair, J., Spencer, S., Taylor, V., Tomlinson, C., Ward, S., Wealleans, V., West, J., White, K., Williams, J., Wilson, L., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A. A., Buth, J., Pattynama, P. M., Verhoeven, E. L. G., van Voorthuisen, A. E., Blankensteijn, J. D., Balm, R., Buth, J., Cuypers, P. W. M., Grobbee, D. E., Prinssen, M., van Sambeek, M. R. H. M., Verhoeven, E. L. G., Baas, A. F., Hunink, M. G., van Engelshoven, J. M., Jacobs, M. J. H. M., de Mol, B. A. J. M., van Bockel, J. H., Balm, R., Reekers, J., Tielbeek, X., Verhoeven, E. L. G., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., Prinssen, M., Balm, R., Blankensteijn, J. D., Buth, J., Cuypers, P. W. M., van Sambeek, M. R. H. M., Verhoeven, E. L. G., de Bruin, J. L., Baas, A. F., Blankensteijn, J. D., Prinssen, M., Buth, J., Tielbeek, A.V., Blankensteijn, J. D., Balm, R., Reekers, J. A., van Sambeek, M. R. H. M., Pattynama, P., Verhoeven, E. L. G., Prins, T., van der Ham, A. C., van der Velden, J. J. I. M., van Sterkenburg, S. M. M., ten Haken, G. B., Bruijninckx, C. M. A., van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A. W., Odink, H. F., de Smet, A. A. E. A., Vroegindeweij, D., van Loenhout, R. M. M., Rutten, M. J., Hamming, J. F., Lampmann, L. E. H., Bender, M. H. M., Pasmans, H., Vahl, A. C., de Vries, C., Mackaay, A. J. C., van Dortmont, L. M. C., van der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H. B., van Dop, H. R., de Mol van Otterloo, J. C. A., de Rooij, T. P. W., Smits, T. M., Yilmaz, E. N., Wisselink, W., van den Berg, F. G., Visser, M. J. T., van der Linden, E., Schurink, G. W. H., de Haan, M., Smeets, H. J., Stabel, P., van Elst, F., Poniewierski, J., Vermassen, F. E. G., Lederle, F. A., Freischlag, J. A., Kohler, T. R., Latts, E., Matsumura, J., Padberg, F. T., Jr, Kyriakides, T. C., Swanson, K. M., Guarino, P., Peduzzi, P., Antonelli, M., Cushing, C., Davis, E., Durant, L., Joyner, S., Kossack, the late A., Kyriakides, T. C., LeGwin, Mary, McBride, V., OʼConnor, T., Poulton, J., Stratton, the late S., Zellner, S., Snodgrass, A. J., Thornton, J., Swanson, K. M., Haakenson, C. M., Stroupe, K.T., Jonk, Y., Hallett, J. W., Hertzer, N., Towne, J., Katz, D. A., Karrison, T., Matts, J. P., Marottoli, R., Kasl, S., Mehta, R., Feldman, R., Farrell, W., Allore, H., Perry, E., Niederman, J., Randall, F., Zeman, M., Beckwith, the late D., OʼLeary, T. J., Huang, G. D., Latts, E., Bader, M., Ketteler, E. R., Kingsley, D. D., Marek, J. M., Massen, R. J., Matteson, B. D., Pitcher, J. D., Langsfeld, M., Corson, J. D., Goff, J. M., Jr, Kasirajan, K., Paap, C., Robertson, D. C., Salam, A., Veeraswamy, R., Milner, R., Kasirajan, K., Guidot, J., Lal, B. K., Busuttil, S. J., Lilly, M. P., Braganza, M., Ellis, K., Patterson, M. A., Jordan, W. D., Whitley, D., Taylor, S., Passman, M., Kerns, D., Inman, C., Poirier, J., Ebaugh, J., Raffetto, J., Chew, D., Lathi, S., Owens, C., Hickson, K., Dosluoglu, H. H., Eschberger, K., Kibbe, M. R., Baraniewski, H. M., Matsumura, J., Endo, M., Busman, A., Meadows, W., Evans, M., Giglia, J. S., El Sayed, H., Reed, A. B., Ruf, M., Ross, S., Jean‐Claude, J. M., Pinault, G., Kang, P., White, N., Eiseman, M., Jones, the late R., Timaran, C. H., Modrall, J. G., Welborn, M. B., III, Lopez, J., Nguyen, T., Chacko, J. K. Y., Granke, K., Vouyouka, A. G., Olgren, E., Chand, P., Allende, B., Ranella, M., Yales, C., Whitehill, T. A., Krupski, the late W. C., Nehler, M. R., Johnson, S. P., Jones, D. N., Strecker, P., Bhola, M. A., Shortell, C. K., Gray, J. L., Lawson, J. H., McCann, R., Sebastian, M.W., Kistler Tetterton, J., Blackwell, C., Prinzo, P. A., Lee, N., Padberg, F. T., Jr, Cerveira, J. J., Lal, B. K., Zickler, R. W., Hauck, K. A., Berceli, S. A., Lee, W. A., Ozaki, C. K., Nelson, P. R., Irwin, A. S., Baum, R., Aulivola, B., Rodriguez, H., Littooy, F. N., Greisler, H., OʼSullivan, M. T., Kougias, P., Lin, P. H., Bush, R. L., Guinn, G., Bechara, C., Cagiannos, C., Pisimisis, G., Barshes, N., Pillack, S., Guillory, B., Cikrit, D., Lalka, S. G., Lemmon, G., Nachreiner, R., Rusomaroff, M., OʼBrien, E., Cullen, J. J., Hoballah, J., Sharp, W. J., McCandless, J. L., Beach, V., Minion, D., Schwarcz, T. H., Kimbrough, J., Ashe, L., Rockich, A., Warner‐Carpenter, J., Moursi, M., Eidt, J. F., Brock, S., Bianchi, C., Bishop, V., Gordon, I. L., Fujitani, R., Kubaska, S. M., III, Behdad, M., Azadegan, R., Ma Agas, C., Zalecki, K., Hoch, J. R., Carr, S. C., Acher, C., Schwarze, M., Tefera, G., Mell, M., Dunlap, B., Rieder, J., Stuart, J. M., Weiman, D. S., Abul‐Khoudoud, O., Garrett, H. E., Walsh, S. M., Wilson, K. L., Seabrook, G. R., Cambria, R. A., Brown, K. R., Lewis, B. D., Framberg, S., Kallio, C., Barke, R. A., Santilli, S. M., dʼAudiffret, A. C., Oberle, N., Proebstle, C., Johnson, L. L., Jacobowitz, G. R., Cayne, N., Rockman, C., Adelman, M., Gagne, P., Nalbandian, M., Caropolo, L. J., Pipinos, I. I., Johanning, J., Lynch, T., DeSpiegelaere, H., Purviance, G., Zhou, W., Dalman, R., Lee, J. T., Safadi, B., Coogan, S. M., Wren, S. M., Bahmani, D. D., Maples, D., Thunen, S., Golden, M. A., Mitchell, M. E., Fairman, R., Reinhardt, S., Wilson, M. A., Tzeng, E., Muluk, S., Peterson, N. M., Foster, M., Edwards, J., Moneta, G. L., Landry, G., Taylor, L., Yeager, R., Cannady, E., Treiman, G., Hatton‐Ward, S., Salabsky, the late B., Kansal, N., Owens, E., Estes, M., Forbes, B. A., Sobotta, C., Rapp, J. H., Reilly, L. M., Perez, S. L., Yan, K., Sarkar, R., Dwyer, S. S., Perez, S., Chong, K., Kohler, T. R., Hatsukami, T. S., Glickerman, D. G., Sobel, M., Burdick, T. S., Pedersen, K., Cleary, P., Back, M., Bandyk, D., Johnson, B., Shames, M., Reinhard, R. L., Thomas, S. C., Hunter, G. C., Leon, L. R., Jr, Westerband, A., Guerra, R. J., Riveros, M., Mills, J. L., Sr, Hughes, J. D., Escalante, A. M., Psalms, S. B., Day, N. N., Macsata, R., Sidawy, A., Weiswasser, J., Arora, S., Jasper, B. J., Dardik, A., Gahtan, V., Muhs, B. E., Sumpio, B. E., Gusberg, R. J., Spector, M., Pollak, J., Aruny, J., Kelly, E. L., Wong, J., Vasilas, P., Joncas, C., Gelabert, H. A., DeVirgillio, C., Rigberg, D. A., Cole, L., Becquemin, J.‐P., Marzelle, J., Becquemin, J.‐P., Sapoval, M., Becquemin, J.‐P., Favre, J.‐P., Watelet, J., Lermusiaux, P., Sapoval, M., Lepage, E., Hemery, F., Dolbeau, G., Hawajry, N., Cunin, P., Harris, P., Stockx, L., Chatellier, G., Mialhe, C., Fiessinger, J.‐N., Pagny, L., Kobeiter, H., Boissier, C., Lacroix, P., Ledru, F., Pinot, J.‐J., Deux, J.‐F., Tzvetkov, B., Duvaldestin, P., Watelet, J., Jourdain, C., David, V., Enouf, D., Ady, N., Krimi, A., Boudjema, N., Jousset, Y., Enon, B., Blin, V., Picquet, J., LʼHoste, P., Thouveny, F., Borie, H., Kowarski, S., Pernes, J.‐M., Auguste, M., Becquemin, J.‐P., Desgranges, P., Allaire, E., Marzelle, J., Kobeiter, H., Meaulle, P.‐Y., Chaix, D., Juliae, P., Fabiani, J. N., Chevalier, P., Combes, M., Seguin, A., Belhomme, D., Sapoval, M., Baque, J., Pellerin, O., Favre, J. P., Barral, X., Veyret, C., Watelet, J., Peillon, C., Plissonier, D., Thomas, P., Clavier, E., Lermusiaux, P., Martinez, R., Bleuet, F., C, Dupreix, Verhoye, J. P., Langanay, T., Heautot, J. F., Koussa, M., Haulon, S., Halna, P., Destrieux, L., Lions, C., Wiloteaux, S., Beregi, J. P., Bergeron, P., Pinot, J.‐J., Patra, P., Costargent, A., Chaillou, P., DʼAlicourt, A., Goueffic, Y., Cheysson, E., Parrot, A., Garance, P., Demon, A., Tyazi, A., Pillet, J.‐C., Lescalie, F., Tilly, G., Steinmetz, E., Favier, C., Brenot, R., Krause, D., Cercueil, J. P., Vahdat, O., Sauer, M., Soula, P., Querian, A., Garcia, O., Levade, M., Colombier, D., Cardon, J.‐M., Joyeux, A., Borrelly, P., Dogas, G., Magnan, P.‐É., Branchereau, A., Bartoli, J.‐M., Hassen‐Khodja, R., Batt, M., Planchard, P.‐F., Bouillanne, P.‐J., Haudebourg, P., Bayne, J., Gouny, P., Badra, A., Braesco, J., Nonent, M., Lucas, A., Cardon, A., Kerdiles, Y., Rolland, Y., Kassab, M., Brillu, C., Goubault, F., Tailboux, L., Darrieux, H., Briand, O., Maillard, J.‐C., Varty, K., and Cousins, C.

Published
2017
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3. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms

Author

van Schaik, Theodorus G., Yeung, Kak K., Verhagen, Hence J., de Bruin, Jorg L., van Sambeek, Marc R.H.M., Balm, Ron, Zeebregts, Clark J., van Herwaarden, Joost A., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A.A., Buth, J., Pattynama, P. M., Verhoeven, E. L.G., van Voorthuisen, A. E., Balm, R., Cuypers, P. W.M., Prinssen, M., van Sambeek, M. R.H.M., Baas, A. F., Hunink, M. G., van Engelshoven, J. M., Jacobs, M. J.H.M., de Mol, B. A.J.M., van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., de Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., van der Ham, A. C., van der Velden, J. J.I.M., van Sterkenburg, S. M.M., ten Haken, G. B., Bruijninckx, C. M.A., van Overhagen, H., Nolthenius, Tutein R.P., Hendriksz, T. R., Teijink, J. A.W., Odink, H. F., de Smet, A. A.E.A., Vroegindeweij, D., van Loenhout, R. M.M., Rutten, M. J., Hamming, J. F., Lampmann, L. E.H., Bender, M. H.M., Pasmans, H., Vahl, A. C., de Vries, C., Mackaay, A. J.C., van Dortmont, L. M.C., van der Vliet, A. J., Kool, Schultze L.J., Boomsma, J. H.B., van Dop, H. R., de Mol van Otterloo, J. C.A., de Rooij, T. P.W., Smits, T. M., Yilmaz, E. N., van den Berg, F. G., Visser, M. J.T., van der Linden, E., Schurink, G. W.H., de Haan, M., Smeets, H. J., Stabel, P., van Elst, F., Poniewierski, J., and Vermassen, F. E.G.

Published
2017
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4. Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine Lung Cancer (nNGM)

Author

Janning, M., primary, Süptitz, J., additional, Albers-Leischner, C., additional, Delpy, P., additional, Tufman, A., additional, Velthaus-Rusik, J.-L., additional, Reck, M., additional, Jung, A., additional, Kauffmann-Guerrero, D., additional, Bonzheim, I., additional, Brändlein, S., additional, Hummel, H.-D., additional, Wiesweg, M., additional, Schildhaus, H.-U., additional, Stratmann, J.A., additional, Sebastian, M., additional, Alt, J., additional, Buth, J., additional, Esposito, I., additional, Berger, J., additional, Tögel, L., additional, Saalfeld, F.C., additional, Wermke, M., additional, Merkelbach-Bruse, S., additional, Hillmer, A.M., additional, Klauschen, F., additional, Bokemeyer, C., additional, Buettner, R., additional, Wolf, J., additional, Loges, S., additional, Simon, Ronald, additional, Sauter, Guido, additional, Volk, Alexander, additional, Neumann, Jens, additional, Klauschen, Frederick, additional, Weichert, Wilko, additional, Kalhori, Naser, additional, Lüthen, Reinhard, additional, Stöhr, Robert, additional, Schubart, Chistoph, additional, Wacker, Heidemarie, additional, Fuchs, Florian, additional, Hartmann, Nils, additional, Graf, Stefanie, additional, Brandts, Christian, additional, Wild, Peter, additional, Demes, Melanie, additional, Reis, Henning, additional, and Rohde, Gernot, additional

Published
2022
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5. Treatment outcome of atypical EGFR mutations in the German National Network Genomic Medicine Lung Cancer (nNuM)

Author

Janning, M., Sueptitz, J., Albers-Leischner, C., Delpy, P., Tufman, A., Velthaus-Rusik, J-L, Reck, M., Jung, A., Kauffmann-Guerrero, D., Bonzheim, I, Braendlein, S., Hummel, H-D, Wiesweg, M., Schildhaus, H-U, Stratmann, J. A., Sebastian, M., Alt, J., Buth, J., Esposito, I, Berger, J., Toegel, L., Saalfeld, F. C., Wermke, M., Merkelbach-Bruse, S., Hillmer, A. M., Klauschen, F., Bokemeyer, C., Buettner, R., Wolf, J., Loges, S., Janning, M., Sueptitz, J., Albers-Leischner, C., Delpy, P., Tufman, A., Velthaus-Rusik, J-L, Reck, M., Jung, A., Kauffmann-Guerrero, D., Bonzheim, I, Braendlein, S., Hummel, H-D, Wiesweg, M., Schildhaus, H-U, Stratmann, J. A., Sebastian, M., Alt, J., Buth, J., Esposito, I, Berger, J., Toegel, L., Saalfeld, F. C., Wermke, M., Merkelbach-Bruse, S., Hillmer, A. M., Klauschen, F., Bokemeyer, C., Buettner, R., Wolf, J., and Loges, S.

Abstract

Background: Atypical EGFR mutations occur in 10%-30% of non-small-cell lung cancer (NSCLC) patients with EGFR mutations and their sensitivity to classical epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKI) is highly heterogeneous. Patients harboring one group of uncommon, recurrent EGFR mutations (G719X, 57681, L861Q) respond to EGFR-TKI. Exon 20 insertions are mostly insensitive to EGFR-TKI but display sensitivity to exon 20 inhibitors. Clinical outcome data of patients with very rare point and compound mutations upon systemic treatments are still sparse to date. Patients and methods: In this retrospective, multicenter study of the national Network Genomic Medicine (nNGM) in Germany, 856 NSCLC cases with atypical EGFR mutations including co-occurring mutations were reported from 12 centers. Clinical follow-up data after treatment with different EGFR-TKIs, chemotherapy and immune checkpoint inhibitors were available from 260 patients. Response to treatment was analyzed in three major groups: (i) uncommon mutations (G719X, 57681, L861Q and combinations), (ii) exon 20 insertions and (iii) very rare EGFR mutations (very rare single point mutations, compound mutations, exon 18 deletions, exon 19 insertions). Results: Our study comprises the largest thus far reported real-world cohort of very rare EGFR single point and compound mutations treated with different systemic treatments. We validated higher efficacy of EGFR-TKI in comparison to chemotherapy in group 1 (uncommon), while most exon 20 insertions (group 2) were not EGFR-TKI responsive. In addition, we found TKI sensitivity of very rare point mutations (group 3) and of complex EGFR mutations containing exon 19 deletions or L858R mutations independent of the combination partner. Notably, treatment responses in group 3 (very rare) were highly heterogeneous. Co-occurring TP53 mutations exerted a non-significant trend for a detrimental effect on outcome in EGFR-TKI-treated patients in groups 2 and

Published
2022

37. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Author

Halliday, A, Harrison, M, Hayter, E, Kong, X, Mansfield, A, Marro, J, Pan, H, Peto, R, Potter, J, Rahimi, K, Rau, A, Robertson, S, Streifler, J, Thomas, D, Fraedrich G, Asymptomatic Carotid Surgery Trial Collaborative G. r. o. u. p., Schmidauer, C, Hölzenbein, Th, Huk, I, Haumer, M, Kretschmer, G, Metz, V, Polterauer, P, Teufelsbauer, H, Cras, P, Hendriks, J, Lauwers, P, Van Schil, P, de Souza EB, Dourado, Me, Gurgel, G, Rocha, Gm, Petrov, V, Slabakov, G, Cooper, Me, Gubitz, G, Holness, R, Howes, W, Langille, R, Legg, K, Nearing, S, Mackean, G, Mackay, M, Phillips, Sj, Sullivan, J, Wood, J, Erdelez, L, Sosa, T, Angelides, Ns, Christopoulos, G, Malikidou, A, Pesta, A, Ambler, Z, Mracek, J, Polivka, J, Rohan, V, Sevcik, P, Simaná, J, Benes, V, Kramár, F, Kaste, M, Lepäntalo, M, Soinne, L, Cardon, Jm, Legalou, A, Gengenbach, B, Pfadenhauer, K, Wölfl, Kd, Flessenkämper, I, Klumpp, Bf, Marsch, J, Kolvenbach, R, Pfeiff, T, Sandmann, W, Beyersdorf, F, Hetzel, A, Sarai, K, Schöllhorn, J, Spillner, G, Lutz, Hj, Böckler, D, Maeder, N, Busse, O, Grönniger, J, Haukamp, F, Balzer, K, Knoob, Hg, Roedig, G, Virreira, L, Franke, S, Moll, R, Schneider, J, Dayantas, J, Sechas, Mn, Tsiaza, S, Kiskinis, D, Apor, A, Dzinich, C, Entz, L, Hüttl, K, Jàrànyi, Z, Mogan, I, Nagy, Z, Szabo, A, Varga, D, Juhász, G, Mátyás, L, Hutchinson, M, Mehigan, D, Aladjem, Z, Harah, E, Elmakias, S, Gurvich, D, Yoffe, B, Ben Meir, H, Dagan, L, Karmeli, R, Keren, G, Shimony, A, Weller, B, Avrahami, R, Koren, R, Streifler, Jy, Tabachnik, S, Zelikovski, A, Angiletta, D, Federico, F, Impedovo, G, Marotta, V, Pascazio, L, Regina, G, Andreoli, A, Pozzati, E, Bonardelli, S, Giulini, Sm, Guarneri, B, Caiazzo, P, Mascoli, F, Becchi, G, Masini, R, Santoro, E, Simoni, G, Ventura, M, Scarpelli, P, Spartera, C, Arena, O, Collice, M, Puttini, M, Romani, F, Santilli, I, Segramora, V, Sterzi, R, Deriu, G, Verlato, F, Cao, Pg, Cieri, Enrico, De Rango, P, Moggi, L, Ricci, S, Antico, A, Spigonardo, F, Malferrari, G, Tusini, N, Vecchiati, E, Cavallaro, A, Kasemi, H, Marino, M, Sbarigia, E, Speziale, F, Zinicola, N, Alò, Fp, Bartolini, M, Carbonari, L, Caporelli, S, Grili Cicilioni, C, Lagalla, G, Ioannidis, G, Pagliariccio, G, Silvestrini, M, Palombo, D, Peinetti, F, Adovasio, R, Chiodo Grandi, F, Mase, G, Zamolo, F, Fregonese, V, Gonano, N, Mozzon, L, Blair, R, Chuen, J, Ferrar, D, Garbowski, M, Hamilton, Mj, Holdaway, C, Muthu, S, Shakibaie, F, Vasudevan, Tm, Kroese, A, Slagsvold, Ce, Dahl, T, Johnsen, Hj, Lange, C, Myhre, Ho, Gniadek, J, Andziak, P, Elwertowski, M, Leszczynski, J, Malek, Ak, Mieszkowski, J, Noszczyk, W, Szostek, M, Toutounchi, S, Correia, C, Pereira, Mc, Akchurin, Rs, Flis, V, Miksic, K, Stirn, B, Tetickovic, E, Cairols, M, Capdevila, Jm, Iborra Ortega, E, Obach, V, Riambau, V, Vidal Barraquer, F, Vila Coll, R, Diaz Vidal, E, Iglesias Negreia JI, Tovar Pardo, A, Iglesias, Rj, Alfageme, Af, Barba Velez, A, Estallo Laliena, L, Garcia Monco JC, Gonzalez, Lr, Corominas, C, Julia, J, Lozano, P, Marti Masso JF, Porta, Rm, Carrera, Ar, Gomez, J, Blomstrand, C, Gelin, J, Holm, J, Karlström, L, Mattsson, E, Bornhov, S, Dahlstrom, J, De Pedis, G, Jensen, Sm, Pärsson, H, Plate, G, Qvarfordt, P, Arvidsson, B, Brattström, L, Forssell, C, Potemkowski, A, Skiöldebrand, C, Stoor, P, Blomqvist, M, Calander, M, Lundgren, F, Almqvist, H, Norgren, L, Norrving, B, Ribbe, E, Thörne, J, Gottsäter, A, Mätzsch, T, Nilsson, Me, Lonsson, M, Stahre, B, Stenberg, B, Konrad, P, Jarl, L, Lundqvist, L, Olofsson, P, Rosfors, S, Swedenborg, J, Takolander, R, Bergqvist, D, Ljungman, C, Kniemeyer, Hw, Widmer, Mk, Kuster, R, Kaiser, R, Nagel, W, Sege, D, Weder, B, De Nie, J, Doelman, J, Yilmaz, N, Buth, J, Stultiens, G, Boiten, J, Boon, A, van der Linden, F, Busman, Dc, Sinnige, Ha, Yo, Ti, de Borst GJ, Eikelboom, Bc, Kappelle, Lj, Moll, F, Dortland, Rw, Westra, Te, Jaber, H, Manaa, J, Meftah, Rb, Nabil, Br, Sraieb, T, Bateman, D, Budd, J, Horrocks, M, Kivela, M, Shaw, L, Walker, R, D'Sa, Aa, Fullerton, K, Hannon, R, Hood, Jm, Lee, B, Mcguigan, K, Morrow, J, Reid, J, Soong, Cv, Simms, M, Baird, R, Campbell, M, Cole, S, Ferguson, It, Lamont, P, Mitchell, D, Sassano, A, Smith, Fc, Blake, K, Kirkpatrick, Pj, Martin, P, Turner, C, Clegg, Jf, Crosley, M, Hall, J, De Cossart, L, Edwards, P, Fletcher, D, Rosser, S, Mccollum, Pt, Davidson, D, Levison, R, Bradbury, Aw, Chalmers, Rt, Dennis, M, Murie, J, Ruckley, Cv, Sandercock, P, Campbell, Wb, Frankel, T, Gardner Thorpe, C, Gutowski, N, Hardie, R, Honan, W, Niblett, P, Peters, A, Ridler, B, Thompson, Jf, Bone, I, Welch, G, Grocott, Ec, Overstall, P, Aldoori, Mi, Dafalla, Be, Bryce, J, Clarke, C, Ming, A, Wilkinson, Ar, Bamford, J, Berridge, D, Scott, J, Abbott, Rj, Naylor, R, Harris, P, Humphrey, P, Adiseshiah, M, Aukett, M, Baker, D, Bishop, Cc, Boutin, A, Brown, M, Burke, P, Burnand, Kg, Colchester, A, Coward, L, Davies, Ah, Espasandin, M, Giddings, Ae, Hamilton, G, Judge, C, Kakkos, S, Mcguiness, C, Morris Vincent, P, Nicolaides, A, Padayachee, Ts, Riordan, H, Sullivan, E, Taylor, P, Thompson, M, Wolfe, Jh, Mccollum, Cn, O'Neill, Pa, Welsh, S, Barnes, J, Cleland, P, Davis, M, Gholkar, A, Jones, R, Jaykishnam, V, Mendelow, Ad, O'Connell, Je, Siddique, Ms, Stansby, G, Vivar, R, Ashley, S, Cosgrove, C, Gibson, J, Wilkins, Dc, Chant, Ad, Frankel, J, Shearman, Cp, Williams, J, Hall, G, Holdsworth, R, Davies, Jn, Mclean, B, Woodburn, Kr, Brown, G, Curley, P, Loizou, L, Chaturvedi, S, Diaz, F, Radak, D, Todorovic, Pr, Kamugasha, D, Baxter, A, Berry, C, Burrett, J, Collins, R, Crowther, J, Davies, C, Farrell, B, Godwin, J, Gray, R, Harwood, C, Hirt, L, Hope, C, Knight, S, Lay, M, Munday, A, Murawska, A, Peto, Cg, Radley, A, Richards, S., Cras, Patrick, van Schil, Paul, et al., Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group, Halliday, A, Harrison, M, Hayter, E, Kong, X, Mansfield, A, Marro, J, Pan, H, Peto, R, Potter, J, Rahimi, K, Rau, A, Robertson, S, Streifler, J, Thomas, D, Adovasio, Roberto, and Asymptomatic Carotid Surgery Trial Collaborative, Group

Subjects
Male, Time Factors, medicine.medical_treatment, Kaplan-Meier Estimate, Carotid endarterectomy, Aged, 80 and over, Carotid Stenosis, Endarterectomy, Carotid, Female, Humans, Incidence, Middle Aged, Primary Prevention, Stroke, Treatment Outcome, Stroke/epidemiology, law.invention, Randomized controlled trial, law, Aged, 80 and over, Endarterectomy, Carotid, endarterectomy, Carotid Stenosis/mortality, Incidence (epidemiology), Carotid*/mortality, General Medicine, Carotid Stenosis | Internal Carotid Artery | Endarterectomy, medicine.symptom, medicine.medical_specialty, Asymptomatic, Internal medicine, asymptomatic carotid artery stenosi, medicine, asymptomatic carotid artery stenosis, business.industry, Carotid Stenosis/complications, Stroke/prevention & control, Perioperative, medicine.disease, Surgery, Stenosis, Human medicine, business
Abstract

SummaryBackgroundIf carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.MethodsBetween 1993 and 2003, 3120 asymptomatic patients from 126 centres in 30 countries were allocated equally, by blinded minimised randomisation, to immediate CEA (median delay 1 month, IQR 0·3–2·5) or to indefinite deferral of any carotid procedure, and were followed up until death or for a median among survivors of 9 years (IQR 6–11). The primary outcomes were perioperative mortality and morbidity (death or stroke within 30 days) and non-perioperative stroke. Kaplan-Meier percentages and logrank p values are from intention-to-treat analyses. This study is registered, number ISRCTN26156392.Findings1560 patients were allocated immediate CEA versus 1560 allocated deferral of any carotid procedure. The proportions operated on while still asymptomatic were 89·7% versus 4·8% at 1 year (and 92·1% vs 16·5% at 5 years). Perioperative risk of stroke or death within 30 days was 3·0% (95% CI 2·4–3·9; 26 non-disabling strokes plus 34 disabling or fatal perioperative events in 1979 CEAs). Excluding perioperative events and non-stroke mortality, stroke risks (immediate vs deferred CEA) were 4·1% versus 10·0% at 5 years (gain 5·9%, 95% CI 4·0–7·8) and 10·8% versus 16·9% at 10 years (gain 6·1%, 2·7–9·4); ratio of stroke incidence rates 0·54, 95% CI 0·43–0·68, p

Published
2010
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38. Procedure-related mortality of endovascular abdominal aortic aneurysm repair using revised reporting standards

Author

Konig, G.G., Vallabhneni, S.R., Marrewijk, C.J. van, Leurs, L.J., Laheij, R.J.F., and Buth, J.

Subjects
Genomic disorders and inherited multi-system disorders [IGMD 3], Genetic defects of metabolism [UMCN 5.1], Nutrition and Health [UMCN 5.5]
Abstract

Contains fulltext : 53262.pdf (Publisher’s version ) (Open Access) OBJECTIVE: The aim of this study was to evaluate the definition of Procedure-related mortality after endovascular aneurysm repair (EVAR) as defined by the Committee for Standardized Reporting Practices in Vascular Surgery. METHODS: Data on patients with an AAA were taken from the EUROSTAR database. The patients underwent EVAR between June 1996 and February 2004 and were analyzed retrospectively. Explicit probability of cause of death was recorded. The time interval from operation, hospital discharge or second interventions till death was recorded. RESULTS: A total of 589 out of 5612 patients (10.5%) died after EVAR in total follow up and all causes of death were included. 141 (2.5%) patients died due to aneurysms reported after the EVAR procedure of which 28 (4.8%) were ruptures, 25 (4.2%) graft-infections and 88 (14.9%) patients who died within 30 days after the initial procedure (present definition, also known as short term clinical outcome). In addition 25 patients died after 30 days, but were then (at moment of death) still in the hospital, or were transferred to a nursing home for further re-evaluation, or needed second interventions. Taking into account the duration of hospitalization and mortality immediately after procedure-related second interventions, 49 delayed deaths might also be regarded as being EVAR procedure-related. CONCLUSION: Delayed deaths are a considerable proportion of procedure-related deaths after EVAR within the revised time frame.

Published
2007

39. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms

Author

Schaik, T.G (Theo) van, Yeung, K.K. (Kak), Verhagen, H.J.M. (Hence), Bruin, J.L. (J.) de, Sambeek, M.R.H.M. (Marc) van, Balm, R. (Ron), Zeebregts, C.J. (Clark), Herwaarden, J.A. (Joost) van, Blankensteijn, J.D. (Jan), Grobbee, D.E. (Diederick), Bak, A.A.A. (A. A.A.), Buth, J. (Jaap), Pattynama, P.M.T. (Peter M.T.), van Voorthuisen, A.E. (A. E.), Cuypers, P.M.W. (Philippe), Prinssen, M. (M.), Verhoeven, E.L.G. (Eric), Baas, A.F. (Annette), Hunink, M.G.M. (Myriam), Engelshoven, J.M. (Jos), Jacobs, M. (Michael), Mol, B.A.J.M. de, Bockel, J.H. van, Reekers, J.A. (Jim), Tielbeek, X., Wisselink, W. (W.), Boekema, N., Heuveling, L.M. (L. M.), Sikking, I., Prinssen, M. (Monique), Bruin, J.L. (Jorg) de, Tielbeek, A.V. (Alexander), Schaik, T.G (Theo) van, Yeung, K.K. (Kak), Verhagen, H.J.M. (Hence), Bruin, J.L. (J.) de, Sambeek, M.R.H.M. (Marc) van, Balm, R. (Ron), Zeebregts, C.J. (Clark), Herwaarden, J.A. (Joost) van, Blankensteijn, J.D. (Jan), Grobbee, D.E. (Diederick), Bak, A.A.A. (A. A.A.), Buth, J. (Jaap), Pattynama, P.M.T. (Peter M.T.), van Voorthuisen, A.E. (A. E.), Cuypers, P.M.W. (Philippe), Prinssen, M. (M.), Verhoeven, E.L.G. (Eric), Baas, A.F. (Annette), Hunink, M.G.M. (Myriam), Engelshoven, J.M. (Jos), Jacobs, M. (Michael), Mol, B.A.J.M. de, Bockel, J.H. van, Reekers, J.A. (Jim), Tielbeek, X., Wisselink, W. (W.), Boekema, N., Heuveling, L.M. (L. M.), Sikking, I., Prinssen, M. (Monique), Bruin, J.L. (Jorg) de, and Tielbeek, A.V. (Alexander)

Abstract

Objective Randomized trials have shown an initial survival benefit of endovascular over conventional open abdominal aortic aneurysm repair but no long-term difference up to 6 years after repair. Longer follow-up may be required to demonstrate the cumulative negative impact on survival of higher reintervention rates associated with endovascular repair. Methods We updated the results of the Dutch Randomized Endovascular Aneurysm Management (DREAM) trial, a multicenter, randomized controlled trial comparing open with endovascular aneurysm repair, up to 15 years of follow-up. Survival and reinterventions were analyzed on an intention-to-treat basis. Causes of death and secondary interventions were compared by use of an events per person-year analysis. Results There were 178 patients randomized to open and 173 to endovascular repair. Twelve years after randomization, the cumulative overall survival rates were 42.2% for open and 38.5% for endovascular repair, for a difference of 3.7 percentage points (95% confidence interval, −6.7 to 14.1; P =.48). The cumulative rates of freedom from reintervention were 78.9% for open repair and 62.2% for endovascular repair, for a difference of 16.7 percentage points (95% confidence interval, 5.8-27.6; P =.01). No differences were observed in causes of death. Cardiovascular and malignant disease account for the majority of deaths after prolonged follow-up. Conclusions During 12 years of follow-up, there was no survival difference between patients who underwent open or endovascular abdominal aortic aneurysm

Published
2017
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40. Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms

Author

Zorgeenheid Vaatchirurgie Medisch, UMC Utrecht, Circulatory Health, Cardiovasculaire Epi Team 9, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts-assistenten Radiotherapie, Arts-assistenten Radiologie, Onderzoek CTC, Other research (not in main researchprogram), Psychiatrie_Medisch, ZL Algemene Neurologie Medisch, Pathologie Pathologen staf, Arts-Assistenten Onderwijs Radiologie, HAG Netwerken, van Schaik, Theodorus G., Yeung, Kak K., Verhagen, Hence J., De Bruin, Jorg Lucas, van Sambeek, Marc R.H.M., Balm, Ron, Zeebregts, Clark J., van Herwaarden, Joost A., Blankensteijn, Jan D., Grobbee, D. E., Bak, Annette A A, Buth, J., Pattynama, Peter M., Verhoeven, E.L.G., Van Voorthuisen, A. E., Balm, R., Cuypers, P.W.M., Prinssen, M., van Sambeek, M.R.H.M., Baas, A. F., Hunink, M. G. Myriam, van Engelshoven, J.M., Jacobs, M. J.H.M., de Mol, Bas A J M, van Bockel, J.H., Reekers, J.A., Tielbeek, X., Wisselink, W., Boekema-Bakker, N., Heuveling, L. M., Sikking, I., van der Velden, J. J.I.M., van Loenhout, R. M.M., Rutten, M. J., Bender, M. H.M., Boomsma, J. H.B., Visser, M. J.T., de Haan, M., Smeets, H. J., DREAM trial participants, Zorgeenheid Vaatchirurgie Medisch, UMC Utrecht, Circulatory Health, Cardiovasculaire Epi Team 9, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts-assistenten Radiotherapie, Arts-assistenten Radiologie, Onderzoek CTC, Other research (not in main researchprogram), Psychiatrie_Medisch, ZL Algemene Neurologie Medisch, Pathologie Pathologen staf, Arts-Assistenten Onderwijs Radiologie, HAG Netwerken, van Schaik, Theodorus G., Yeung, Kak K., Verhagen, Hence J., De Bruin, Jorg Lucas, van Sambeek, Marc R.H.M., Balm, Ron, Zeebregts, Clark J., van Herwaarden, Joost A., Blankensteijn, Jan D., Grobbee, D. E., Bak, Annette A A, Buth, J., Pattynama, Peter M., Verhoeven, E.L.G., Van Voorthuisen, A. E., Balm, R., Cuypers, P.W.M., Prinssen, M., van Sambeek, M.R.H.M., Baas, A. F., Hunink, M. G. Myriam, van Engelshoven, J.M., Jacobs, M. J.H.M., de Mol, Bas A J M, van Bockel, J.H., Reekers, J.A., Tielbeek, X., Wisselink, W., Boekema-Bakker, N., Heuveling, L. M., Sikking, I., van der Velden, J. J.I.M., van Loenhout, R. M.M., Rutten, M. J., Bender, M. H.M., Boomsma, J. H.B., Visser, M. J.T., de Haan, M., Smeets, H. J., and DREAM trial participants

Published
2017

41. Quality of Life after Endovascular and Open AAA Repair. Results of a Randomised Triala

Author

Prinssen, M., Buskens, E., Blankensteijn, Jan D., Buth, J., Tielbeek, A. V., Verhoeven, E. L.G., Prins, T., Hamming, J. F., Lampmann, L. E.H., Schurink, G. W.H., de Haan, M., Balm, R., Reekers, J. A., Bender, M. H.M., Pasmans, H., Visser, M. J.T., van der Linden, E., Blankensteijn, J. D., de Smet, A. A.E.A., Vroegindeweij, D., van Sterkenburg, S. M.M., ten Haken, G. B., Boomsma, J. B.B., van Dop, H. R., de Mol van Otterloo, J. C.A., de Rooij, T. P.W., van Sambreek, M. R.H.M., Pattynama, P., Bruijninckx, C. M.A., van Overhagen, H., van der Ham, A. C., van der Velden, J. J.I.M., Wisselink, W., van den Berg, F. G., Tutein Nolthenius, R. P., Hendriksz, T. R., Vahl, A. C., de Vries, C., Mackaay, A. J.C., Smeets, H. J., van Dortmont, L. M.C., Elsman, B. H.P., Smits, T. M., van Loenhout, R. M.M., Rutten, M. J., Teijink, J. A.W., Odink, H. F., Yilmaz, E. N., den Butter, G., Poniewierski, J., Vermassen, F. E.G., Stabel, P., van Elst, F., Epidemiology and Data Science, Pathology, Surgery, ACS - Atherosclerosis & ischemic syndromes, and Radiology and nuclear medicine

Subjects
Male, Quality of life, medicine.medical_specialty, Time Factors, Health Status, Population, law.invention, Aortic aneurysm, Aneurysm, Randomized controlled trial, law, Surveys and Questionnaires, medicine, Humans, EVAR, Postoperative Period, education, Heart, lung and circulation [UMCN 2.1], Aged, Medicine(all), education.field_of_study, business.industry, Open AAA repair, Recovery of Function, medicine.disease, Abdominal aortic aneurysm, humanities, Surgery, Clinical trial, Randomised trail, Female, Cardiology and Cardiovascular Medicine, business, Vascular Surgical Procedures, Abdominal surgery, Aortic Aneurysm, Abdominal, DREAM-trial
Abstract

Contains fulltext : 57956.pdf (Publisher’s version ) (Closed access) AIM: To compare the quality of life (QoL) in the first postoperative year after elective endovascular abdominal aortic aneurysm repair (EVAR) and open repair (OR) in a randomised study. METHODS: In the Dutch Randomised Endovascular Aneurysm Management (DREAM) trial, patients are randomly allocated to EVAR or OR. QoL questionnaires (SF-36 and EuroQoL-5D) were sent to all patients preoperatively (PREOP) and at five time points in the first postoperative year (3W, 6W, 3M, 6M and 12M). Between November 1999 and August 2002, 153 patients (141 male; 12 female) were randomised (78 EVAR and 75 OR; one crossover from OR to EVAR). The EuroQoL-5D scores and the eight domains of the SF-36 for the two groups were compared using the Mann-Whitney test. Changes over time were analysed using the Wilcoxon sign test. RESULTS: There were no statistically significant differences in baseline characteristics (age, gender and SVS risk factors). The preoperative QoL scores of the study group were similar to the QoL scores of the general population of the same age. After 3W the OR group showed a significant decrease on the EuroQol-5D (p=0.022) and in six of the eight SF-36 domains. The EVAR group also showed a significant decrease on the EuroQol-5D (p=0.004) and in 5 of the 8 domains of the SF-36. At 6W the EuroQol-5D had recovered to baseline in the OR group and the decreased domains of the SF-36 had partially recovered. In the EVAR group the EuroQol-5D and three of the five decreased SF-36 domains, had returned to baseline. From 6M on, the OR group reported a significantly higher score on the EuroQoL-5D than the EVAR group (p=0.045 (6M) and p=0.001 (12M)). CONCLUSION: In the early postoperative period there is a small, yet significant QoL advantage for EVAR compared to OR. At 6 months and beyond, patients reported better QoL after OR than after EVAR.

Published
2004
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42. Collected world and single center experience with endovascular treatment of ruptured abdominal aortic aneurysms

Author

Veith, F. J, Lachat, M, Mayer, D, Malina, M, Holst, J, Mehta, M, Verhoeven, E. L. G, Larzon, T, Gennai, S, Coppi, G, Lipsitz, E. C, Gargiulo, N. J, van der Vliet, J. A, Blankensteijn, J, Buth, J, Lee, W. A, Deleo, G, Kasirajan, K, Moore, R, Soong, C. V, Cayne, NS, Farber, MA, Raithel, D, Greenberg, RK, van Sambeek, MRHM, Brunkwall, JS, Rockman, CB, Hinchliffe, RJ, RAAA Investigators: Adiseshiah, M, Alimi, Y, Bekkema, F, Bell, P, Becquemin, JP, Benatti, C, Braithwaite, B, Camesasca, W, Cao, P, Casali, R, Castellani, L, Chester, J, Criado, F, Cuypers, P, Dake, M, Darling, RC, Eliasson, K, Fillinger, M, Gloviczki, P, Goode, S, Gruber, G, Hopkinson, B, Hodgson, K, Ivancev, K, Kapma, M, Koskas, F, Liapis, C, Long, J, Loan, W, MacSweeney, S, Makaroun, M, Matsumura, J, Matyas, L, May, J, Moore, W, Pamler, R, Parodi, J, Paty, P, Sunder Plassmann, L, Pfammatter, T, Peppelenbosch, N, Piglionica, M, Ross, J, Resch, T, Roddy, S, Rubin, B, Saitta, G, Sales, C, Sanchez, L, Silingardi, R, Sonesson, B, Taggert, J, Sternbach, Y, Toivola, A, van den Berg, J, van Dijk, L, Vermassen, F, Villa, V, White, R, Zipfel, B., BIASI, GIORGIO MARIA, FROIO, ALBERTO, University of Zurich, Faculteit Medische Wetenschappen/UMCG, Veith, F, Lachat, M, Mayer, D, Malina, M, Holst, J, Mehta, M, Verhoeven, E, Larzon, T, Gennai, S, Coppi, G, Lipsitz, E, Gargiulo, N, van der Vliet, J, Blankensteijn, J, Buth, J, Lee, W, Biasi, G, Deleo, G, Kasirajan, K, Moore, R, Soong, C, Cayne, N, Farber, M, Raithel, D, Greenberg, R, van Sambeek, M, Brunkwall, J, Rockman, C, Hinchliffe, R, RAAA Investigators: Adiseshiah, M, Alimi, Y, Bekkema, F, Bell, P, Becquemin, J, Benatti, C, Braithwaite, B, Camesasca, W, Cao, P, Casali, R, Castellani, L, Chester, J, Criado, F, Cuypers, P, Dake, M, Darling, R, Eliasson, K, Fillinger, M, Froio, A, Gloviczki, P, Goode, S, Gruber, G, Hopkinson, B, Hodgson, K, Ivancev, K, Kapma, M, Koskas, F, Liapis, C, Long, J, Loan, W, Macsweeney, S, Makaroun, M, Matsumura, J, Matyas, L, May, J, Moore, W, Pamler, R, Parodi, J, Paty, P, Sunder Plassmann, L, Pfammatter, T, Peppelenbosch, N, Piglionica, M, Ross, J, Resch, T, Roddy, S, Rubin, B, Saitta, G, Sales, C, Sanchez, L, Silingardi, R, Sonesson, B, Taggert, J, Sternbach, Y, Toivola, A, van den Berg, J, van Dijk, L, Vermassen, F, Villa, V, White, R, and Zipfel, B

Subjects
medicine.medical_specialty, collected international experience, Abdominal compartment syndrome, Decompression, medicine.medical_treatment, Aortic Rupture, 610 Medicine & health, Balloon, Single Center, Endovascular aneurysm repair, Aortic aneurysm, Blood Vessel Prosthesis Implantation, abdominal aortic aneurysm rupture, medicine.artery, Surveys and Questionnaires, medicine, MED/22 - CHIRURGIA VASCOLARE, Humans, Endovascular treatment, endovascualr treatment, Cardiovascular diseases [NCEBP 14], business.industry, 10042 Clinic for Diagnostic and Interventional Radiology, Data Collection, Abdominal aorta, medicine.disease, Surgery, 10020 Clinic for Cardiac Surgery, 2746 Surgery, Aneurysm, endovascular repair, rupture, open repair, endograft, Radiology, business, Aortic Aneurysm, Abdominal
Abstract

Contains fulltext : 81133.pdf (Publisher’s version ) (Closed access) BACKGROUND: Case and single center reports have documented the feasibility and suggested the effectiveness of endovascular aneurysm repair (EVAR) of ruptured abdominal aortic aneurysms (RAAAs), but the role and value of such treatment remain controversial. OBJECTIVE: To clarify these we examined a collected experience with use of EVAR for RAAA treatment from 49 centers. METHODS: Data were obtained by questionnaires from these centers, updated from 13 centers committed to EVAR treatment whenever possible and included treatment details from a single center and information on 1037 patients treated by EVAR and 763 patients treated by open repair (OR). RESULTS: Overall 30-day mortality after EVAR in 1037 patients was 21.2%. Centers performing EVAR for RAAAs whenever possible did so in 28% to 79% (mean 49.1%) of their patients, had a 30-day mortality of 19.7% (range: 0%-32%) for 680 EVAR patients and 36.3% (range: 8%-53%) for 763 OR patients (P < 0.0001). Supraceliac aortic balloon control was obtained in 19.1% +/- 12.0% (+/-SD) of 680 EVAR patients. Abdominal compartment syndrome was treated by some form of decompression in 12.2% +/- 8.3% (+/-SD) of these EVAR patients. CONCLUSION: These results indicate that EVAR has a lower procedural mortality at 30 days than OR in at least some patients and that EVAR is better than OR for treating RAAA patients provided they have favorable anatomy; adequate skills, facilities, and protocols are available; and optimal strategies, techniques, and adjuncts are employed.

Published
2009

43. Predicting reinterventions after open and endovascular aneurysm repair using the St George's Vascular Institute score

Author

De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., Vermassen, F. E G, De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., and Vermassen, F. E G

Published
2016

44. Predicting reinterventions after open and endovascular aneurysm repair using the St George's Vascular Institute score

Author

Cardiovasculaire Epi Team 9, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts Assistenten CTC, Psychiatrie_Medisch, Pathologie Pathologen staf, Arts-assistenten Radiologie, PCR MN, Other research (not in main researchprogram), JC Overig onderzoek, De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., Vermassen, F. E G, Cardiovasculaire Epi Team 9, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Genetica Klinische Genetica, Arts Assistenten CTC, Psychiatrie_Medisch, Pathologie Pathologen staf, Arts-assistenten Radiologie, PCR MN, Other research (not in main researchprogram), JC Overig onderzoek, De Bruin, Jorg Lucas, Karthikesalingam, Alan, Holt, Peter J., Prinssen, Monique, Thompson, Matt M., Blankensteijn, Jan D., Grobbee, D. E., Blankensteijn, J. D., Bak, A. A A, Buth, J., Pattynama, P. M., Verhoeven, E. L G, Van Voorthuisen, A. E., Balm, R., Cuypers, P. W M, Prinssen, M., Van Sambeek, M. R H M, Baas, A. F., Hunink, M. G., Van Engelshoven, J. M., Jacobs, M. J H M, De Mol, B. A J M, Van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., De Bruin, J. L., Tielbeek, A. V., Reekers, J. A., Pattynama, P., Prins, T., Van Der Ham, A. C., Van Der Velden, J. J I M, Van Sterkenburg, S. M M, Ten Haken, G. B., Bruijninckx, C. M A, Van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A W, Odink, H. F., De Smet, A. A E A, Vroegindeweij, D., Van Loenhout, R. M M, Rutten, M. J., Hamming, J. F., Lampmann, L. E H, Bender, M. H M, Pasmans, H., Vahl, A. C., De Vries, C., MacKaay, A. J C, Van Dortmont, L. M C, Van Der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H B, Van, H. R., De Mol Van Otterloo, J. C A, De Rooij, T. P W, Smits, T. M., Yilmaz, E. N., Van Den Berg, F. G., Visser, M. J T, Van Der Linden, E., Schurink, G. W H, De Haan, M., Smeets, H. J., Stabel, P., Van Elst, F., Poniewierski, J., and Vermassen, F. E G

Published
2016

45. Predicting reinterventions after open and endovascular aneurysm repair using the St George's Vascular Institute score

Author

de Bruin, Jorg Lucas, primary, Karthikesalingam, Alan, additional, Holt, Peter J., additional, Prinssen, Monique, additional, Thompson, Matt M., additional, Blankensteijn, Jan D., additional, Grobbee, D.E., additional, Blankensteijn, J.D., additional, Bak, A.A.A., additional, Buth, J., additional, Pattynama, P.M., additional, Verhoeven, E.L.G., additional, van Voorthuisen, A.E., additional, Balm, R., additional, Cuypers, P.W.M., additional, Prinssen, M., additional, van Sambeek, M.R.H.M., additional, Baas, A.F., additional, Hunink, M.G., additional, van Engelshoven, J.M., additional, Jacobs, M.J.H.M., additional, de Mol, B.A.J.M., additional, van Bockel, J.H., additional, Reekers, J., additional, Tielbeek, X., additional, Wisselink, W., additional, Boekema, N., additional, Heuveling, L.M., additional, Sikking, I., additional, de Bruin, J.L., additional, Tielbeek, A.V., additional, Reekers, J.A., additional, Pattynama, P., additional, Prins, T., additional, van der Ham, A.C., additional, van der Velden, J.J.I.M., additional, van Sterkenburg, S.M.M., additional, ten Haken, G.B., additional, Bruijninckx, C.M.A., additional, van Overhagen, H., additional, Tutein Nolthenius, R.P., additional, Hendriksz, T.R., additional, Teijink, J.A.W., additional, Odink, H.F., additional, de Smet, A.A.E.A., additional, Vroegindeweij, D., additional, van Loenhout, R.M.M., additional, Rutten, M.J., additional, Hamming, J.F., additional, Lampmann, L.E.H., additional, Bender, M.H.M., additional, Pasmans, H., additional, Vahl, A.C., additional, de Vries, C., additional, Mackaay, A.J.C., additional, van Dortmont, L.M.C., additional, van der Vliet, A.J., additional, Schultze Kool, L.J., additional, Boomsma, J.H.B., additional, van, H.R., additional, de Mol van Otterloo, J.C.A., additional, de Rooij, T.P.W., additional, Smits, T.M., additional, Yilmaz, E.N., additional, van den Berg, F.G., additional, Visser, M.J.T., additional, van der Linden, E., additional, Schurink, G.W.H., additional, de Haan, M., additional, Smeets, H.J., additional, Stabel, P., additional, van Elst, F., additional, Poniewierski, J., additional, and Vermassen, F.E.G., additional

Published
2016
Full Text
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46. Abdominal aneurysm repair

Author

Sambeek, Marc, Cuypers, Judith, Hendriks, Joke, Buth, J, Hallet, Mills, Earnshaw, Reekers, Rooke, Anesthesiology, Cardiology, and Surgery

Published
2009

47. A prognostic model for amputation in critical lower limb ischemia

Author

Klomp, H. M., Steyerberg, E. W., Wittens, C. H.A., van Urk, H., Habbema, J. D.F., van den Dungen, J. J.A.M., Staal, M. J., van Det, R. J., van de Aa, H. E., Kole, E. A., Moll, F. L., Liem, A. L., van Dijk, H. A., Theuvenet, P. J., Sier, J. C., Lambooy, N., Yo, T. I., Kazemier, G., duBois, N. A.J.J., Veeger, A. I., Buth, J., Bollen, E. C.M., Lens, J., Spincemaille, G. H., Hollander, W., Hoofwijk, A. G.M., Tordoir, J. H.M., Bikkers, T. H.A., van Lent, D., van Elk, P. J., Jacobs, M. J.H.M., Ubbink, D. Th, van der Ham, A. C., Surgery, ACS - Atherosclerosis & ischemic syndromes, APH - Quality of Care, APH - Personalized Medicine, and Public Health

Subjects
Male, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Critical Illness, Arterial Occlusive Diseases, Electric Stimulation Therapy, Constriction, Pathologic, Kaplan-Meier Estimate, Risk Assessment, Severity of Illness Index, Amputation, Surgical, Ischemia, Risk Factors, Peripheral arterial disease, Medicine, Humans, Predictive value of tests, Treatment Failure, Risk factor, Amputation, Aged, Netherlands, Proportional Hazards Models, Gangrene, Aged, 80 and over, business.industry, Proportional hazards model, Vascular disease, Hazard ratio, Leg Ulcer, Cardiovascular Agents, Critical limb ischemia, Middle Aged, medicine.disease, Prognosis, Surgery, Radiography, Spinal Nerves, Lower Extremity, Randomized controlled trials, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

Abstract In a (negative) multicenter randomized trial on management for inoperable critical lower limb ischemia, comparing spinal cord stimulation and best medical treatment, a number of pre-defined factors were analyzed for prognostic value. We included a radiological arterial disease score, modified from the SVS/ISCVS runoff score. The purpose of this analysis was to evaluate clinical factors and commonly used circulatory measurements for prognostic modeling in patients with critical lower limb ischemia. We determined the incidence of amputation and its relation to various pre-defined risk factors. A total of 120 patients with critical limb ischemia were included in the study. The integrity of circulation in the affected limb was evaluated on five levels: suprainguinal, infrainguinal, popliteal, infrapopliteal and pedal. A total radiological arterial disease score was calculated from 1 (full integrity of circulation) to 20 (maximally compromised state). We used Cox regression analysis to quantify prognostic effects and differential treatment (predictive) effects. Major amputation occurred in 33% of the patients at 6 months and in 51% at 2 years. The presence of ischemic skin lesions and the radiological arterial disease score were independent prognostic factors for amputation. Patients with ulcerations or gangrene had a higher amputation risk (hazard ratio 2.38, p = 0.018 and 2.30, p = 0.036 respectively) as well as patients with a higher radiological arterial disease score (hazard ratio 1.17 per increment, p = 0.003). We did not observe significant interactions between prognostic factors and the effect of spinal cord stimulation. In conclusion, in patients with critical lower limb ischemia, the presence of ischemic skin lesions and the described radiological arterial disease score can be used to estimate amputation risk.

Published
2009

50. Determination of linear viscoelastic behavior of abdominal aortic aneurysm thrombus

Author

Dam, van, E.A., Dams, S.D., Peters, G.W.M., Rutten, M.C.M., Schurink, G.W.H., Buth, J., Vosse, van de, F.N., Cardiovascular Biomechanics, Soft Tissue Biomech. & Tissue Eng., and Processing and Performance

Subjects
cardiovascular system, cardiovascular diseases, circulatory and respiratory physiology
Abstract

The objective of this study is to determine whether the linear viscoelastic properties of an abdominal aortic aneurysm thrombus can be determined by rheometry.Although large strains occur in the in vivo situation, in this work only linear behavior is studied to show the applicability of the described methods. A thrombusexists of several layers that vary in composition, structure and mechanical properties.Two types of thrombus are described. In discrete transition thrombi the layers are not or at most weakly attached to each other and the structure of each layer is different. Continuous transition thrombi consist of strongly attached layers whose structure changes gradually throughout the thickness of the thrombus.Shear experiments are performed on samples from both types of thrombus on a rotational rheometer using a parallel plate geometry. In the discrete type the storage modulus G0 cannot be assumed equal for the different layers. In the continuous thrombus, G0, changes gradually throughout the layered structure. In both types the loss modulus, G00, does not vary throughout the thrombus. Furthermore, it was found that Time Temperature Superposition is applicable to thrombus tissue. Since results were reproducible it can be concluded that the method we used to determine the viscoelastic properties is applicable to thrombus tissue.

Published
2006

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