1. Efficacy of a randomized trial examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women
- Author
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Richard B. Kreider, Elfego Galvan, Chris Rasmussen, Ryan Dalton, Mike Greenwood, Majid Koozehchian, Sunday Simbo, Adriana M. Coletta, Brittanie Lockard, Andrew R. Jagim, Kyle Levers, Deepesh Khanna, Julie Y. Kresta, C Baetge, Michael J. Byrd, Jonathan M. Oliver, Brittany Sanchez, Conrad P. Earnest, and Y. Peter Jung
- Subjects
medicine.medical_specialty ,Diet, Reducing ,Physiology ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Overweight ,Body Mass Index ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Double-Blind Method ,Randomized controlled trial ,Risk Factors ,law ,Weight loss ,Physiology (medical) ,Internal medicine ,Weight Loss ,Prevalence ,medicine ,Chi-square test ,Humans ,Obesity ,030212 general & internal medicine ,Exercise ,Metabolic Syndrome ,Nutrition and Dietetics ,business.industry ,Resistance Training ,General Medicine ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Texas ,Confidence interval ,Cardiorespiratory Fitness ,Physical therapy ,Patient Compliance ,Female ,Insulin Resistance ,Sedentary Behavior ,medicine.symptom ,Metabolic syndrome ,Energy Intake ,business ,Body mass index ,Follow-Up Studies - Abstract
While commercial dietary weight-loss programs typically advise exercise, few provide actual programing. The goal of this study was to compare the Curves Complete 90-day Challenge (CC, n = 29), which incorporates exercising and diet, to programs advocating exercise (Weight Watchers Points Plus (WW, n = 29), Jenny Craig At Home (JC, n = 27), and Nutrisystem Advance Select (NS, n = 28)) or control (n = 20) on metabolic syndrome (MetS) and weight loss. We randomized 133 sedentary, overweight women (age, 47 ± 11 years; body mass, 86 ± 14 kg; body mass index, 35 ± 6 kg/m2) into respective treatment groups for 12 weeks. Data were analyzed using chi square and general linear models adjusted for age and respective baseline measures. Data are means ± SD or mean change ± 95% confidence intervals (CIs). We observed a significant trend for a reduction in energy intake for all treatment groups and significant weight loss for all groups except control: CC (−4.32 kg; 95% CI, −5.75, −2.88), WW (−4.31 kg; 95% CI, −5.82, −2.96), JC (−5.34 kg; 95% CI, −6.86, −3.90), NS (−5.03 kg; 95% CI, −6.49, −3.56), and control (0.16 kg, 95% CI, −1.56, 1.89). Reduced MetS prevalence was observed at follow-up for CC (35% vs. 14%, adjusted standardized residuals (adjres.) = 3.1), but not WW (31% vs. 28% adjres. = 0.5), JC (37% vs. 42%, adjres. = −0.7), NS (39% vs. 50% adjres. = −1.5), or control (45% vs. 55% adjres. = −1.7). While all groups improved relative fitness (mL·kg−1·min−1) because of weight loss, only the CC group improved absolute fitness (L/min). In conclusion, commercial programs offering concurrent diet and exercise programming appear to offer greater improvements in MetS prevalence and cardiovascular function after 12 weeks of intervention.
- Published
- 2017
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