Beverley J. Hunt, Radko Komadina, Timothy J Coats, Vladimir Cerny, Arthur Schultz, Yves Ozier, Enrique Fernández-Mondéjar, Jean Louis Vincent, Jacques Duranteau, Giuseppe Nardi, Daniela Filipescu, Louis Riddez, Rolf Rossaint, Donat R. Spahn, Edmund Neugebauer, Bertil Bouillon, University of Zurich, Spahn, Donat R, [Rossaint,R] Department of Anaesthesiology, University Hospital Aachen, RWTH Aachen University, Aachen, Germany. [Bouillon,B] Department of Trauma and Orthopaedic Surgery, Witten/Herdecke University, Cologne-Merheim Medical Centre, Cologne, Germany. [Cerny,V] Department of Anaesthesiology, Perioperative Medicine and Intensive Care, J.E. Purkinje University, Masaryk Hospital, Usti nad Labem, Czech Republic. Department of Research and Development, Charles University in Prague, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic. Department of Anaesthesiology and Intensive Care, Charles University in Prague, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic. Department of Anaesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, QE II Health Sciences Centre, Halifax, Canada. [Coats,TJ] Emergency Medicine Academic Group, University of Leicester, Leicester, UK. [Duranteau,J] Department of Anaesthesia and Intensive Care, Hôpitaux Universitaires Paris Sud, University of Paris, Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, Cedex, France. [Fernández-Mondéjar,E] Servicio de Medicina Intensiva, Complejo Hospitalario Universitario de Granada, Granada, Spain. [Filipescu,D] Department of Cardiac Anaesthesia and Intensive Care, C. C. Iliescu Emergency Institute of Cardiovascular Diseases, Bucharest, Romania. [Hunt,BJ] King’s College, Departments of Haematology, Pathology and Lupus, Guy’s and St Thomas’ NHS Foundation Trust,London, UK. [Komadina,R] Department of Traumatology, General and Teaching Hospital Celje, Celje, Slovenia. [Nardi,G] Shock and Trauma Centre, S. Camillo Hospital, Rome, Italy. [Neugebauer,EAM] Faculty of Health - School of Medicine, Witten/Herdecke University, Cologne, Germany. [Ozier,Y] Division of Anaesthesia, Intensive Care and Emergency Medicine, Brest University Hospital, Brest, France. [Riddez,L] Department of Surgery and Trauma, Karolinska University Hospital, Solna, Sweden. [Schultz,A] Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Lorenz Boehler Trauma Centre, Vienna, Austria. [Vincent,JL] Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium. [Spahn,DR] Institute of Anaesthesiology, University of Zurich and University Hospital Zurich, Zurich, Switzerland., and The development of this guideline was initiated and performed by the authors as members of the Task Force for Advanced Bleeding Care in Trauma. Members of the task force were compensated for their presence at one face-to-face meeting, but not for the time invested in developing and reviewing the recommendations or manuscript. Meeting organisation and medical writing support for literature searches and manuscript preparation were provided by Physicians World Europe GmbH (Mannheim, Germany). Costs incurred for medical writing support, travel, hotel accommodation, meeting facilities, honoraria and publication were supported by unrestricted grants from CSL Behring GmbH (Marburg, Germany) and LFB Biomédicaments (Courtaboeuf, France).